Document Detail


1-Amino-1-deoxy-D-fructose ("fructosamine") and its derivatives.
MedLine Citation:
PMID:  20837201     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fructosamine has long been considered as a key intermediate of the Maillard reaction, which to a large extent is responsible for specific aroma, taste, and color formation in thermally processed or dehydrated foods. Since the 1980s, however, as a product of the Amadori rearrangement reaction between glucose and biologically significant amines such as proteins, fructosamine has experienced a boom in biomedical research, mainly due to its relevance to pathologies in diabetes and aging. In this chapter, we assess the scope of the knowledge on and applications of fructosamine-related molecules in chemistry, food, and health sciences, as reflected mostly in publications within the past decade. Methods of fructosamine synthesis and analysis, its chemical, and biological properties, and degradation reactions, together with fructosamine-modifying and -recognizing proteins are surveyed.
Authors:
Valeri V Mossine; Thomas P Mawhinney
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in carbohydrate chemistry and biochemistry     Volume:  64     ISSN:  0065-2318     ISO Abbreviation:  Adv Carbohydr Chem Biochem     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-14     Completed Date:  2011-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0240537     Medline TA:  Adv Carbohydr Chem Biochem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-402     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Biochemistry, University of Missouri, Columbia, Missouri 65211, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Enzymes / metabolism
Food
Fructosamine / analogs & derivatives*,  chemistry,  metabolism,  pharmacology
Glycoconjugates / chemistry,  metabolism
Humans
Maillard Reaction
Plants / chemistry,  metabolism
Chemical
Reg. No./Substance:
0/Enzymes; 0/Glycoconjugates; 4429-04-3/Fructosamine

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