| 1-Amino-1-deoxy-D-fructose ("fructosamine") and its derivatives. | |
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MedLine Citation:
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PMID: 20837201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fructosamine has long been considered as a key intermediate of the Maillard reaction, which to a large extent is responsible for specific aroma, taste, and color formation in thermally processed or dehydrated foods. Since the 1980s, however, as a product of the Amadori rearrangement reaction between glucose and biologically significant amines such as proteins, fructosamine has experienced a boom in biomedical research, mainly due to its relevance to pathologies in diabetes and aging. In this chapter, we assess the scope of the knowledge on and applications of fructosamine-related molecules in chemistry, food, and health sciences, as reflected mostly in publications within the past decade. Methods of fructosamine synthesis and analysis, its chemical, and biological properties, and degradation reactions, together with fructosamine-modifying and -recognizing proteins are surveyed. |
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Authors:
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Valeri V Mossine; Thomas P Mawhinney |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Advances in carbohydrate chemistry and biochemistry Volume: 64 ISSN: 0065-2318 ISO Abbreviation: Adv Carbohydr Chem Biochem Publication Date: 2010 |
Date Detail:
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Created Date: 2010-09-14 Completed Date: 2011-01-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0240537 Medline TA: Adv Carbohydr Chem Biochem Country: United States |
Other Details:
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Languages: eng Pagination: 291-402 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Biochemistry, University of Missouri, Columbia, Missouri 65211, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Enzymes / metabolism Food Fructosamine / analogs & derivatives*, chemistry, metabolism, pharmacology Glycoconjugates / chemistry, metabolism Humans Maillard Reaction Plants / chemistry, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Enzymes; 0/Glycoconjugates; 4429-04-3/Fructosamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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