| 0.75% and 0.5% ropivacaine for axillary brachial plexus block: a clinical comparison with 0.5% bupivacaine. | |
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MedLine Citation:
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PMID: 10588554 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND OBJECTIVES: Although ropivacaine has been extensively studied for epidural anesthesia, very few reports exist on brachial plexus block. We therefore decided to investigate the clinical features of axillary brachial plexus anesthesia with two different concentrations of ropivacaine (0.5% and 0.75%) and to compare the results with those obtained with 0.5% bupivacaine. METHODS: Three groups of patients were randomized and prospectively studied. They received, in a double-blind fashion, 32 mL of the local anesthetic solution into the midaxilla, by a nerve-stimulator technique. Onset time in each of the stimulated nerves was recorded both for the sensory and motor block. Peak time (ready to surgery), rate of supplemental blocks, need for intraoperative opioids, duration of sensory and motor block, postoperative analgesic requirements, and patient satisfaction were also recorded. RESULTS: The rate of complete sensory and motor block observed with both ropivacaine groups was higher at 10, 15, and 20 minutes postinjection (P < .001). The mean peak time was shorter with ropivacaine than with bupivacaine (R50 = 16.37 minutes, R75 = 14.7 minutes, B = 22.3 minutes, P < .05). The quality of the anesthesia was higher with ropivacaine, as measured by the intraoperative needs for opioids and the overall patient's satisfaction (P < .05). No significant differences were noted with all the other studied parameters. CONCLUSION: Ropivacaine showed advantages over bupivacaine for axillary brachial plexus block. Because no statistical differences were found between the two ropivacaine groups, we therefore conclude that 0.75% does not add benefit and that 0.5% ropivacaine should be used to perform axillary brachial plexus blocks. |
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Authors:
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L Bertini; V Tagariello; S Mancini; A Ciaschi; C M Posteraro; P Di Benedetto; O Martini |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Regional anesthesia and pain medicine Volume: 24 ISSN: 1098-7339 ISO Abbreviation: Reg Anesth Pain Med Publication Date: 1999 Nov-Dec |
Date Detail:
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Created Date: 1999-12-17 Completed Date: 1999-12-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9804508 Medline TA: Reg Anesth Pain Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 514-8 Citation Subset: IM |
Affiliation:
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Department of Anesthesia, Centro Traumatologico Ortopedico, Rome, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Amides / administration & dosage* Anesthetics, Local / administration & dosage* Brachial Plexus / drug effects*, physiology Bupivacaine / administration & dosage* Dose-Response Relationship, Drug Double-Blind Method Humans Middle Aged Nerve Block* Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Amides; 0/Anesthetics, Local; 2180-92-9/Bupivacaine; 84057-95-4/ropivacaine |
| Comments/Corrections | |
Comment In:
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Reg Anesth Pain Med. 2000 Nov-Dec;25(6):659
[PMID:
11097681
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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