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Alex-Hart, Balafama - - 2011
Problem statement: Hand washing with soap is an important means of preventing hospital acquired infections .However the rate of hand washing with soap and water is unacceptably low amongst health workers. Few studies on this subject have been done amongst health workers in Nigeria. The aims of this study were ...
Jahromi, Abdolreza - - 2011
Problem statement: Recurrent abortion is a difficult medical problem happening in about 1-2% of fertile women. Rubella is of high public health importance owing to teratogenic effects that can lead to fetal death, miscarriage, stillbirth, or infants during the first 16 weeks of gestation. As there were not data about ...
Japoni, Aziz - - 2011
Problem statement: Due to continuous changes in the frequencies and antibacterial susceptibility patterns of nosocomial pathogens, periodical surveillance of these fluctuations could help the clinicians to treat hospitalized patients more efficiently whenever empirical therapies need to be considered. This study was conducted to compare the prevalence of the bacteria recovered ...
Arjunan, Maripandi - - 2010
Problem statement: Urinary Tract Infections (UTIs) in human, rural environment cause significant morbidity due to insanitary condition, lack of knowledge of personal hygiene, lack of patient's compliance and economic burden. In our study, the bacterial etiologies and the resistance patterns found in human with serious UTIs and selecting optimal antimicrobial ...
Bandyopadhyay, Bhaswati - - 2010
Problem statement: No specific antiviral therapy is currently available despite an emergence and resurgence of Japanese encephalitis in South-East Asian Countries. There are only few recent studies, which were aimed to treat Japanese encephalitis with newer drugs. There is thus a real need for study on antiviral agents that can ...
Solhjoo, Kavous - - 2010
Problem statement: In situations of immunodeficiency, Toxoplasma gondii emerges as a life-threatening infection. Toxoplasma gondii is transmitted parenterally, flourish in immunocompromised subjects and, most toxoplasma infections are asymptomatic. Studies have shown that there is a immunodeficiency in renal failure patient such as hemodialysis patients and these patients have a high ...
Jahromi, Abdolreza - - 2010
Problem statement: Fetal loss and abortion are responsible for significant emotional distress for couples desiring children. There are many documents which support the role of some certain asymptomatic infections such as Cytomegalovirus (CMV) in spontaneous abortion. This study was aimed to evaluate the prevalence of seropositivity for CMV IgG and ...
Amsterdam, Daniel - - 2010
Problem statement: The Tigecycline Evaluation and Surveillance Trial (TEST) commenced in 2004 to monitor the activity of tigecycline, a new glycylcycline and numerous comparators against major hospital-and community-associated pathogens. In this report we examine the efficacy of tigecycline and comparators against isolates of Staphylococcus aureus collected from blood. Approach: Almost ...
Alvarenga, Christiane - - 2009
Problem statement: The principal aim was to evaluate the effects of dengue virus infection by dengue during pregnancy and analyze the histopathology of the placenta. Approach: A retrospective study was conducted with 13 pregnant women with dengue confirmed in the period from January-December 2002, during a widespread dengue type 3 ...
Kofteridis, Diamantis - - 2009
Problem statement: Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain ...
Wan Norhasima, - - 2009
Problem statements: Fumonisin was a mycotoxin produced mainly by fungi belonging to the genus Fusarium in various foods and feeds. They occurred worldwide and were found predominantly in corn and in corn-based animal feeds and also can be found in other crops. Contamination of food and feed with fumonisins has ...
Irish, Bryan - - 2009
Problem statement: Infection with retroviruses such as human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type 1 (HTLV-1) have been shown to lead to neurodegenerative diseases such as HIV-associated dementia (HAD) or neuroAIDS and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP), respectively. Approach: HIV-1-induced neurologic disease is associated ...
Parekh, Bharat - - 2009
Problem statement: A large number of people in the world have been suffering from gout for centuries. Gout is the term given to a metabolic condition in which the signs and symptoms results from the deposition of crystals of Monosodium Urate Monohydrate (MSUM) in various connective tissues. Approach: It was ...
Rajagopalan, Nirmala - - 2009
Problem statement: Despite massive national efforts to scale up Antiretroviral Therapy (ART) access in India since 2004, the AIDS death rate was 17.2 per 100,000 persons during 2003-2005. In the era of HAART in resource poor settings, it is imperative to understand and address the causes of AIDS related mortality. ...
Suthindhiran, K. - - 2009
Problem statement: Although the diversity of marine Actinobacteria have been studied and biotechnologically exploited throughout the world, the studies on marine actinobacteria in Indian peninsula are largely unexplored. Of 9 maritime states in India, only 4 states have been extensively studied for the diversity of actinobacteria. Further, the studies on ...
Ravada, Suryachandra - - 2009
Problem statement: Co[Q.sub.10] is a key compound in ATP synthesis having wide number of health application especially for treating humans suffering from pathophysiological condition. The Co[Q.sub.10] presently available in the market is solely derived from fermentation process. A commercially viable synthetic process is yet to be realized. Approach: The researchers ...
Kamatchi, C. - - 2009
Problem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and spread of plasmid encoded extended spectrum beta lactamases and other genes conferring cross-resistance to other antibiotics. This is of concern due to the increasing ...
Krishnaraju, Alluri - - 2009
Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and cardiac abnormalities. A safe and effective intervention is essential for the treatment of inflammatory disorders. Approach: Abstract Vitex leucoxylon L., a medicinal plant of the verbenaceae family, used ...
Krishnaraju, Alluri - - 2009
Problem statement: Free radical stress leads to tissue injury and progression of disease conditions such as arthritis, hemorrhagic shock, atherosclerosis, diabetes, hepatic injury, aging and ischemia, reperfusion injury of many tissues, gastritis, tumor promotion, neurodegenerative diseases and carcinogenesis. Safer antioxidants suitable for long term use are needed to prevent or ...
Himabindu, M. - - 2009
Problem statement: To investigate coagulase gene variants through Restriction Fragment Length Polymorphism (RFLP) amongst clinical isolates of Methicillin-Resistant Staphylococcus Aureus (MRSA) collected from Chennai based hospitals. Approach: A total of 85 MRSA clinical isolates collected from various clinical sources were studied for the molecular typing purpose. To perform coagulase gene ...
Raja, Subramaniya - - 2009
Problem statement: Enteropathogenic Escherichia Coli (EPEC) continue to be a major health problem, leading to death due to diarrhea, predominantly in children below the age of five. Due to evolution of multi drug resistance in EPEC and side effects caused to host by antibiotics necessitated a search for alternative medicines ...
Acharya, Hari - - 2009
Problem statement: The medicinal value of opium poppy (2n = 22, Papaver somniferum L.) is due to presence of more than two dozen alkaloids. The genetic origin and diversity of cultivars used in the breeding collection is not fully known. To evaluate the genetic diversity of the 24 germplasm currently ...
Sharma, Ruchi - - 2009
Problem statement: Recombinant-based approaches are mostly focused on genetic modification of allergens to produce molecules with reduced allergenic activity and conserved antigenicity, such as hypoallergens. Recombinant allergens represent promising tools for diagnosis and therapy of type I allergy. This approach was probably feasible with every allergen with known amino acid ...
Nair, Madhavan - - 2009
Problem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NF[kappa]B and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin ...
Salma, Pathan - - 2009
Problem statement: The function of a protein is dependent on its three-dimensional structure. However, numerous proteins lacking intrinsic globular 3D structure under physiological conditions had been recognized. These proteins are frequently involved in some of the most critical cellular control mechanisms and it appears that their rapid turnover, aided by ...
Umathe, Sudhir - - 2009
Problem statement: Quercetin-a common bioflavonoid, is present in herbal preparations consumed by diabetic patients along with routine anti-diabetic agents. We recently showed that quercetin increases the bioavailability of pioglitazone in non-diabetic rats. Thus, present study investigated whether this pharmacokinetic interaction is also evident in diabetic animals, especially because diabetic subjects ...
Kumar, Prasant - - 2009
Problem statement: Gastrointestinal disorders mainly diarrhea is the most common cause of morbidity and mortality among infants and children in the developing countries occurs due to infection by enteropathogens. Ccontrol of these pathogens could be achieved by nonpathogenic Escherichia coli producing bacteriocins. Approach: Primary aim of this study was to ...
Choudhary, Parul - - 2009
Problem statement: Population studies indicate that individuals who regularly consume nuts have reduced risk for cardiovascular diseases and diabetes. The beneficial role of almonds has been established with respect to serum lipid profile however, its beneficial effects on glycemia is still to be established. Aim of the study was to ...
Mahapatra, B. - - 2009
Problem statement: Researchers have demonstrated that epistaxis is more often encountered in patients having blood group O probably due to lower expression of von Willebrand factor. We had taken up this study to find out if there is any definite relationship between the blood groups with the bleeding time and ...
Bhatt, Niraj - - 2009
Problem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the protective effects of Enicostemma littorale Blume (EL) (2.5 g [kg.sup.-1]), a hypoglycemic and antioxidant herbal medicine in alloxan-induced diabetic neuropathy in male ...
Shehabi, A.A. - - 2009
Problem statement: Both M. genitalium and T. vaginalis were recognized as important cause of sexually transmitted infections in developed countries. This study investigated the prevalence of M. genitalium and T. vaginalis in general Jordanian patients and their role of causing genitourinary tract diseases. Approach: A cross sectional study of 383 ...
Malow, Robert - - 2009
The article reports our intervention work with Alcohol and Other Drug Abusing (AOD) People Living With HIV (PLWH). Present research has involved adapting Cognitive Behavioral Stress Management (CBSM) and other strategies to improve quality of life and health outcomes for PLWH. Historically, CBSM has used relaxation and coping skills training ...
Suzita, R. - - 2009
Problem statement: Food borne illness occurs all over the world. Vibrio cholerae is the etiological agent of cholera which is spread by contaminated food, water or direct fecal contact with food handlers. There are also examples of sporadic outbreaks of illness attributed to raw products eaten unprocessed. Consequently, there was ...
Devieux, Jessy - - 2009
Problem statement: Incarcerated youth with borderline symptomatology represent a particularly at risk-population due to their enggement in risky behaviors. Five hundred twenty two adolescents were assessed for borderline symptomatology (MACI), engagement in risky behaviors and attitudes/knowledge. Approach: Adolescents were divided into two groups: low borderline (below the 60 scale score ...
Yao, Honghong - - 2009
Problem statement: It has been well documented that drugs of abuse such as cocaine can cause enhanced progression of HIV-Associated Neuropathological Disorders (HAND), the underlying mechanisms mediating these effects remain poorly understood. Approach: In present study, we explored the impact of cocaine exposure (I and 10 [micro]M) on the dendritic ...
Malekpour-Afshar, Reza - - 2009
Abstract: Problem statement: Post-Traumatic Meningitis (PTM) is a serious complication followed trauma. It sounds to have different pattern and characteristics. The aim of the current study was to determine the characteristics and outcome of PTM in referral neurosurgery department in Iran.
Okesola, A.O. - - 2009
Problem statement: The emergence and spread of resistance to third-generation cephalosporins are threatening to create species resistant to all currently available agents. The most common cause of bacterial resistance to beta-lactam antibiotics is the production of beta-lactamases and many of the 2nd and 3rd-generation penicillins and cephalosporins were specifically designed ...
Salmani, Ali - - 2009
Problem statement: Brucellosis is a globally found infectious disease and there is no licensed vaccine against human brucellosis. The present study carried-out to evaluate the potency of our modified extracted lipopolysaccharide (LPS) of B. abortus to elicit specific anti-Brucella antibodies in animal model (Rabbit) as a part of a candidate ...
Masaadeh, Hani - - 2009
The primary aim of this study was to determine the incidents of pseudomonas aeruginosa in post-operative wound infection and its sensitivity pattern to commonly used antibiotics. During a period of six months between February to December, 2005, 115 specimens were collected from King Abdullah University Hospital, Princess Basma Hospital, Princess ...
Oliveira, L.R. - - 2008
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