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Results 251 - 300 of 852
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Fox Ervin R ER Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA. - - 2011
The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. It is unknown if these variants ...
Azevedo Bruna Fernandes - - 2011
The present studies were conducted to changes arising from mercury poisoning in the central nervous system (CNS), with a focus on determining the receptors and neurotransmitters involved. Currently, little is known regarding the neurological basis of the cardiopulmonary effects of mercury poisoning. We evaluated changes in systolic arterial pressure (SAP), ...
Arora A K - - 2011
Zirconium tungstate turns amorphous above 2 GPa. Amorphous-Zr(WO(4))(2) is studied in situ using synchrotron x-ray diffraction and Raman spectroscopy at high pressure. The height and the position of the first peak of the structure factor as a function of pressure exhibit discontinuous changes suggesting an amorphous to amorphous transformation around 19 GPa. The ...
Potekhin Sergey A - - 2011
The bilayer phase transitions from the ripple gel phase (P'(β)) to the liquid crystal phase (L(α)) of a series of 1,2-diacylphosphatidylcholines containing a linear saturated acyl chain (C=14 - 19) have been studied by high pressure scanning microcalorimetry. It has been shown that at ambient pressure, the transition temperature increases ...
Girard Olivier - - 2011
This study aimed to determine changes in spring-mass model (SMM) characteristics, plantar pressures, and muscle activity induced by the repetition of sprints in soccer-specific conditions; i.e., on natural grass with soccer shoes. Thirteen soccer players performed 6 × 20 m sprints interspersed with 20 s of passive recovery. Plantar pressure distribution was recorded via ...
Hanfland Michael - - 2011
By compressing elemental silicon and hydrogen in a diamond anvil cell, we have synthesized polymeric silicon tetrahydride (SiH_{4}) at 124 GPa and 300 K. In situ synchrotron x-ray diffraction reveals that the compound forms the insulating I4_{1}/a structure previously proposed from ab initio calculations for the high-pressure phase of silane. From a series of ...
Harrison-Bernard Lisa M - - 2011
The renin angiotensin system (RAS) acts as a dual endocrine and local tissue paracrine system (1; 6). There is increasing evidence that angiotensin (ANG) II may also function as an autocrine or intracrine peptide which exerts biological effects from within the cell without stimulating plasma membrane bound ANG II type ...
Kyriakou Zoe - - 2011
The present study is motivated by the fact that there are no published studies quantifying cavitation activity and heating induced by ultrasound in adipose tissue and that there are currently no reliable techniques for monitoring successful deposition of ultrasound energy in fat in real time. High-intensity focused ultrasound (HIFU) exposures ...
Zhang Aihua - - 2011
We assessed the relative contribution of the mitochondrial respiratory chain and NADPH (nicotinamide adenine dinucleotide phosphate) oxidase to deoxycorticosterone acetate (DOCA)-salt hypertension in mice. The daily mean arterial pressure was monitored by radiotelemetry in DOCA-salt-treated mice given vehicle or the mitochondrial respiratory chain complex I inhibitor rotenone. This treatment produced ...
Heikkilä H P - - 2011
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease primarily affecting West Highland White Terriers (WHWTs). Objective: To describe the clinicopathological and diagnostic imaging features in WHWTs with IPF. Animals: Twelve WHWTs with IPF and 14 healthy control WHWTs. Method: Prospective study. Clinical signs and findings of physical ...
Marques Marisa - - 2011
The root cause of capsular contracture (CC) associated with breast implants is unknown. Recent evidence points to the possible role of fibrin and bacteria in CC formation. The authors sought to determine whether fibrin, thrombin, and blood modulated the histological and microbiological outcomes of breast implant capsule formation in a ...
Dehestru Guillaume - - 2011
This article discusses a microfluidic vibrating wire viscometer with an internal volume of a few microliters. Accuracy of order ±10% for viscosities ranging from 0.1 to 100 cP is demonstrated for temperatures (10 °C-175 °C) and pressures (10-24 000 psi) suitable for oilfield use by prior calibration in air and toluene. ...
Kamran Haroon - - 2011
The objective of this study was to evaluate the vascular effects of heart rate (HR) reduction with BB therapy in African Americans (AA). Beta-blockers (BB) offer less cardiovascular protection than other hypertensive drugs. Studies of Caucasian subjects suggest this may be due to an adverse effect of HR lowering on ...
Salamonsen Robert F - - 2011
Responses of four rotary blood pumps (Incor, Heartmate II, Heartware, and Duraheart) at a single speed setting to changes in preload and afterload were assessed using the human left ventricle as a benchmark for comparison. Data for the rotary pumps were derived from pressure flow relations reported in the literature ...
Janssen Christof - - 2011
Preparation of high purity ozone as well as precise and accurate measurement of its pressure are metrological requirements that are difficult to meet due to ozone decomposition occurring in pressure sensors. The most stable and precise transducer heads are heated and, therefore, prone to accelerated ozone decomposition, limiting measurement accuracy ...
Peyton Philip J - - 2011
Rapid elimination of nitrous oxide from the lungs at the end of inhalational anesthesia dilutes alveolar oxygen, producing "diffusion hypoxia." A similar dilutional effect on accompanying volatile anesthetic agent has not been evaluated and may impact the speed of emergence. Twenty patients undergoing surgery were randomly assigned to receive an ...
Haxton Thomas K - - 2011
We present a new formulation of the jamming phase diagram for a class of glass-forming fluids consisting of spheres interacting via finite-ranged repulsions at temperature T, packing fraction ϕ or pressure p, and applied shear stress Σ. We argue that the natural choice of axes for the phase diagram are ...
Ren Ruojin - - 2011
To assess the lumbar cerebrospinal fluid pressure (CSF-P) in ocular hypertensive subjects with elevated intraocular pressure (IOP) but without development of glaucomatous optic nerve damage. The prospective interventional study included 17 patients with ocular hypertension and 71 subjects of a nonglaucomatous control group. All patients underwent a standardized ophthalmologic and ...
Kazi Raisa N - - 2011
α(1D)-Adrenoceptors are involved in the genesis/maintenance of hypertension in spontaneously hypertensive rats (SHR). This study aims to investigate the role of α(1D)-adrenoceptors in the antinatriuretic and antidiuretic responses in SHR subjected to high sodium (SHRHNa) and normal sodium (SHRNNa) intake for six weeks. Renal inulin clearance study was performed in ...
Menni Cristina - - 2011
Objective: To see whether there is interaction between single nucleotide polymorphisms (SNPs) belonging to candidate genes for hypertension and job strain and its components (job demand and job control) in an accurately phenotyped Italian cohort (Pressioni Arteriose Monitorate E Loro Associazioni). Methods: From the Pressioni Arteriose Monitorate E Loro Associazioni ...
Nissim N - - 2011
High pressure ellipsometry (HPE) method was developed for determining the index of refraction of opaque materials in a diamond anvil cell (DAC). A main difficulty in DAC-based HPE, namely, the pressure-induced birefringence developed in the diamond, was overcome enabling the extraction of the ellipsometric parameters of the sample. The method ...
Hattrick-Simpers Jason R - - 2011
An optical cell is described for high-throughput backscattering Raman spectroscopic measurements of hydrogen storage materials at pressures up to 10 MPa and temperatures up to 823 K. High throughput is obtained by employing a 60 mm diameter × 9 mm thick sapphire window, with a corresponding 50 mm diameter unobstructed ...
Klemenc Matjaž - - 2011
Hypoxia decreases baroreflex sensitivity (BRS) and can be a sufficient cause for syncope in healthy individuals. Carbohydrate loading enhances efferent sympathetic activity, which affects cardiac contractility, heart rate and vascular resistance, the main determinants of blood pressure. Thus, in both normoxia and hypoxia, carbohydrate loading may be more than simply ...
Masè Michela - - 2011
We validated a prototype cuff-free device for noninvasive estimation of blood pressure (BP). The system assumed a linear relation between BP values and the inverse of arterial blood pulse transit time, measured as time interval between the R wave on the electrocardiograph and the onset of the peripheral pulse wave ...
Zhang Min - - 2011
To investigate the role of mechanical pressure on cartilage thickness and type II collagen synthesis, and the role of G protein in that process, in vitro organ culture of mandibular cartilage was adopted in this study. A hydraulic pressure-controlled cellular strain unit was used to apply hydrostatic pressurization to explant ...
Rhodes H L - - 2011
Systemic arterial pressure rises on acute exposure to high altitude and changes in blood pressure (BP) and endothelial function may be important in the pathogenesis of clinical syndromes occurring at high altitude. Arterial BP, stiffness (SI) and tone (RI) were studied over 11 days in 17 subjects (three having mild ...
Li Kai-Cheng - - 2011
Prolonged hyperbaric oxygen exposure causes pulmonary and nervous system toxicity, although hyperbaric oxygen treatment has been used to treat a broad spectrum of ailments. In the current study, animals have been exposed to 100% oxygen at a pressure of 2.3 atmospheres absolute (ATA) for two, six and 10 hours or ...
Clayton Hilary M - - 2011
We compared anteroposterior and mediolateral range of motion and velocity of the center of pressure (COP) on the horse's back between riders without disabilities and riders with cerebral palsy. An electronic pressure mat was used to track COP movements beneath the saddle in 4 riders without disabilities and 4 riders ...
Song Yan - - 2011
ABSTRACT?Tubular scaffolds (internal diameter approximately 3 mm and wall thickness approximately 0.8 mm) with a porosity of approximately 83% and an average pore size of 116 µm were prepared from flexible poly(trimethylene carbonate) (PTMC) polymer by dip-coating and particulate leaching methods. PTMC is a flexible and biocompatible polymer that crosslinks ...
Gu Y D - - 2011
The primary objective of this paper is to study the use of medical image-based finite element (FE) modelling in subject-specific midsole design and optimisation for heel pressure reduction using a midsole plug under the calcaneus area (UCA). Plugs with different relative dimensions to the size of the calcaneus of the ...
Lewis N C S - - 2011
Moving rapidly from a supine to a standing posture is a common daily activity, yet a significant physiological challenge. Syncope can result from the development of initial orthostatic hypotension (IOH) involving a transient fall in systolic/diastolic blood pressure (BP) of >40/20 mm Hg within the first 15 s, and/or a ...
Akrawinthawong Krittapoom - - 2011
Beta-thalassemia/HbE (beta-thal/HbE) is a thalassemia intermedia (TI) which encompasses a broad spectrum of severity. Here, we used deferiprone (DFP) as an iron chelating agent in TI patients receiving intermittent blood transfusion who are asymptomatic for cardiovascular disease in order to evaluate the effectiveness in iron overload and reduce the possibility ...
Fulcher Lewis P - - 2011
Pressure distributions for the uniform glottis were obtained with a static physical model (M5). Glottal diameters of d=0.005, 0.0075, 0.01, 0.02, 0.04, 0.08, 0.16, and 0.32 cm were used with a range of phonatory transglottal pressures. At each pressure and diameter, entrance loss and exit coefficients were determined. In general, ...
Rybka J - - 2011
The purpose of this study was to analyze glutathione antioxidant defense system in elderly patients treated for hypertension. Studies were carried out in the blood collected from 18 hypertensive and 15 age- and sex-matched controls, all subjects age over 60. Hypertensives were on their usual antihypertensive treatment at the time ...
Tribst Alline Artigiani Lima - - 2011
This work aimed to evaluate the effect of high-pressure homogenization (HPH) with heat shock on Aspergillus niger, vitamin C, and color of mango nectar. The nectar was processed at 200 MPa followed by heat shock, which was optimized by response surface methodology by using mango nectar ratio (45 to 70), ...
Wang Jian J Center for Cardiovascular Health, Tulane University, New Orleans, LA, - - 2011
Hypertension and left ventricular (LV) hypertrophy are both more common in blacks than in whites. The aim of the present study was to test the hypothesis that blood pressure (BP) has a differential effect on the LV geometry types in black versus white asymptomatic young adults. As a part of ...
Goncharov Alexey A Department of Environmental Health Sciences, School of Public Health, University at Albany, Rensselaer, New York, - - 2011
Residents of Anniston, Alabama, live near a Monsanto plant that manufactured polychlorinated biphenyls (PCBs) from 1929 to 1971 and are relatively heavily exposed. The goal of this study was to determine the relationship, if any, between blood pressure and levels of total serum PCBs, several PCB groups with common actions ...
Baumann Marcus - - 2011
Baseline blood pressure (BP) is the strongest known determinant of progression to hypertension, but for an individualized prediction of the incidence of hypertension, the identification of additional biomarkers is crucial. In animal models of hypertension, renal nitric oxide (NO) handling modifies the systemic BP responses prior to the development of ...
Brown Ian J IJ Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London W2 1PG, United Kingdom. - - 2011
The obesity epidemic has focused attention on relationships of sugars and sugar-sweetened beverages (SSBs) to cardiovascular risk factors. Here we report cross-sectional associations of SSBs, diet beverages, and sugars with blood pressure (BP) for United Kingdom and US participants of the International Study of Macro/Micronutrients and Blood Pressure. Data collected ...
El Moustaine Driss - - 2011
Prion proteins (PrP) can aggregate into toxic and possibly infectious amyloid fibrils. This particular macrostructure confers on them an extreme and still unexplained stability. To provide mechanistic insights into this self-assembly process, we used high pressure as a thermodynamic tool for perturbing the structure of mature amyloid fibrils that were ...
Trinity Joel D JD Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah, USA. - - 2011
This study used alterations in body position to identify differences in hemodynamic responses to passive exercise. Central and peripheral hemodynamics were noninvasively measured during 2 min of passive knee extension in 14 subjects, whereas perfusion pressure (PP) was directly measured in a subset of 6 subjects. Movement-induced increases in leg ...
Schlaich Markus P - - 2011
OBJECTIVE: Polycystic ovary syndrome (PCOS) is associated with sympathetic nervous system activation, insulin resistance, and blood pressure elevation. Renal nerve ablation has been demonstrated to reduce sympathetic outflow and improve blood pressure control. Here we report on the effects of renal denervation on hemodynamic, metabolic, and renal parameters in two ...
Skilton Michael R - - 2011
OBJECTIVE: To determine which metabolic and cardiovascular risk factors are associated with the change in ankle brachial pressure index and incident peripheral arterial disease over 9 years, and whether these associations differ between healthy weight and overweight & obese individuals. METHODS: Metabolic factors, change in ankle brachial pressure index and ...
Liu H - - 2011
We found that very strong negative optical pressure can be induced in plasmonic cavities by LC resonance. This interesting effect could be described qualitatively by a Lagrangian model which shows that the negative optical pressure is driven by the internal inductance and the kinetic energy of the conduction electrons. If ...
Lähde Tero - - 2011
The effects of the fuel injection pressure on a heavy-duty diesel engine exhaust particle emissions were studied. Nonvolatile particle size distributions and gaseous emissions were measured at steady-state engine conditions while the fuel injection pressure was changed. An increase in the injection pressure resulted in an increase in the nonvolatile ...
Demirci Serafettin - - 2011
Increased oxidative stress is a well-known phenomenon in dialysis patients. However, the contribution of hypertension to the oxidative stress in peritoneal dialysis patients has not yet been assessed. The present study aimed to investigate if hypertension had an additional effect on oxidative stress in peritoneal dialysis patients. A total of ...
Nasimi Ali - - 2011
The bed nucleus of the stria terminalis (BST) is a limbic structure involved in cardiovascular regulation and modulation of responses to stress. The BST contains high levels of muscarinic receptors. This study was performed to find the effects of cholinergic system of the BST on the cardiovascular regulation and the ...
Thayer Patrick - - 2011
Aortic valve interstitial cells (VIC) can exhibit phenotypic characteristics of fibroblasts, myofibroblasts, and smooth muscle cells. Others have proposed that valve cells become activated and exhibit myofibroblast or fibroblast characteristics during disease initiation and progression; however, the cues that modulate this phenotypic change remain unclear. We hypothesize that the mechanical ...
Appavou Marie-Sousai - - 2011
Pressure is a ubiquitous physical parameter in life and is commonly used in the life sciences to study new protein folding pathways or association-dissociation phenomena. In this paper, an investigation of the influence of pressure on hemoglobin, a multimeric protein, at the picosecond time scale is presented using time-of-flight neutron ...
Gao Yulong - - 2011
The elimination of spores from low-acid foods presents food-processing and food-safety challenges to high-pressure processing (HPP) developers as bacterial spores are extremely resistant to pressure. Therefore, the effects of pressure (400-800 MPa), temperature (35-95°C), and nisin (0-496 IU/mL) on the inactivation of Clostridium perfringens AS 64701 spores at various pressure-holding times ...
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