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Dursun Nurcan - - 2011
Adriamycin (ADR) causes morphological and functional alterations in mitochondrial structure in the heart. The study's aim was to determine whether there is a protective effect of selenium (Se) on ADR-induced cardiac damage. Rats were divided into four groups: The first group was injected saline intraperitoneally (i.p.) for 21 days; the ...
Kakimi Kazuyuki - - 2011
An eccentric-type tablet machine fitted with 8-mm-diameter flat-faced punches was used to measure the forces of upper and lower punches, die-wall pressure, tablet ejection force, and scraper pressure (SCR), a type of shear stress, to evaluate sticking behavior. The shear stress between the surfaces of the tablet and lower punch ...
Nagabukuro Hiroshi - - 2011
Both the physiological role of muscarinic receptors for bladder function and the therapeutic efficacy of antimuscarinic agents for overactive bladder syndrome are well documented. We investigated the effect of antimuscarinic agents with different subtype selectivity on urodynamic parameters in non-human primates and rodents, and compared plasma levels of these agents ...
Arroyo C - - 2011
The effect of High Hydrostatic Pressure (HHP) on the survival of Cronobacter sakazakii was investigated. Deviations from linearity were found on the survival curves and the Mafart equation accurately described the kinetics of inactivation. Comparisons between strains and treatments were made based on the time needed for a 5-log(10) reduction ...
Wu Christine H - - 2011
To compare values of urodynamic measurements of cats with idiopathic cystitis (IC) with previously published data for healthy female cats. 11 female cats with IC. 2 sequential cystometrograms and 2 urethral pressure profiles were obtained for each cat. All tracings were evaluated for evidence of overactive urinary bladder (OAB). Maximum ...
Yang Jie - - 2011
In this paper, a W-Ta thin-film thermocouple has been integrated on a diamond anvil cell by thin-film deposition and photolithography methods. The thermocouple was calibrated and its thermal electromotive force was studied under high pressure. The results indicate that the thermal electromotive force of the thermocouple exhibits a linear relationship ...
Ng Manwa L - - 2011
The present study investigated the aerodynamic differences between standard oesophageal (SE) and tracheoesophageal (TE) speech. Airflow and air pressure values below the pharyngoesophageal segment were obtained from 10 SE and 12 TE superior speakers of Cantonese. Airflow data were directly measured from sustained vowels, and sub-pharyngoesophageal segment pressure was estimated ...
Wang Lin - - 2011
In this report, we demonstrate the feasibility of applying a 250-nm focused x-ray beam to study a single crystalline NbSe(3) nanobelt under high-pressure conditions in a diamond anvil cell. With such a small probe, we not only resolved the distribution and morphology of each individual nanobelt in the x-ray fluorescence ...
Abdel-Hamid Sameh - - 2011
Context: In tablet manufacturing, less attention is paid to the measurement of die-wall pressure than to force-displacement diagrams. Objective: Therefore, the aim of this study was to investigate radial stress change during pharmaceutical compaction. Materials and Methods: The Presster(TM), a tablet-press replicator was used to characterize compaction behavior of microcrystalline ...
Horn Gavin P - - 2011
Abstract Objectives. The primary objective of this study was to document the timeline of physiologic recovery from firefighting activities in order to inform emergency medical services (EMS) of vital sign values that might be expected during incident rehabilitation and in developing rehabilitation protocols to make decisions about when to return ...
Katiyar Amit - - 2011
Variation of subharmonic response from contrast microbubbles with ambient pressure is numerically investigated for non-invasive monitoring of organ-level blood pressure. Previously, several contrast microbubbles both in vitro and in vivo registered approximately linear (5-15 dB) subharmonic response reduction with 188 mm Hg change in ambient pressure. In contrast, simulated subharmonic ...
Nikitina Elena R - - 2011
Marinobufagenin (MBG), a bufadienolide cardiotonic steroid, induces cardiovascular fibrosis. Because levels of MBG in preeclampsia are increased, and anti-MBG monoclonal antibody reduces blood pressure (BP) in a rat model of preeclampsia, we hypothesized that in preeclampsia, elevated MBG levels would be associated with the development of fibrosis in feto-placental circulation ...
Ely Daniel - - 2011
Sex-determining region Y (Sry) is a transcription factor. Our research group has shown that there are multiple copies of Sry in Wistar-Kyoto (WKY) and spontaneous hypertensive (SHR) rats, and that they have novel functions separate from testes determination. We hypothesized that exogenously delivered Sry3 to the normotensive WKY male kidney ...
Kung Ethan O - - 2011
The purpose of this study is to validate numerical simulations of flow and pressure in an abdominal aortic aneurysm (AAA) using phase-contrast magnetic resonance imaging (PCMRI) and an in vitro phantom under physiological flow and pressure conditions. We constructed a two-outlet physical flow phantom based on patient imaging data of ...
Tam Tam Kiran B KB Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS 39216, - - 2011
We sought to determine the effect of an endothelin type A receptor antagonist (ETA) on uterine artery resistive index (UARI) and mean arterial pressure (MAP) in a placental ischemia rat model of preeclampsia produced by reduction in uterine perfusion pressure (RUPP). UARI was assessed by Doppler velocimetry in RUPP and ...
Davis Michael J MJ Dept. of Medical Pharmacology & Physiology, Univ. of Missouri School of Medicine, 1 Hospital Dr., Rm. M451, Columbia, MO 65212, USA. - - 2011
Secondary lymphatic valves are essential for minimizing backflow of lymph and are presumed to gate passively according to the instantaneous trans-valve pressure gradient. We hypothesized that valve gating is also modulated by vessel distention, which could alter leaflet stiffness and coaptation. To test this hypothesis, we devised protocols to measure ...
Fischbach Michel - - 2011
It is well known that the efficiency of peritoneal dialysis (PD) varies with the duration of the dwell and with the prescribed fill volume. Automated PD (APD) is classically given as a series of recurrent exchanges, each having the same dwell time and fill volume-that is, conventional APD (APD-C). We ...
Shimizu Kazuaki - - 2011
Hypertension promotes and escalates kidney injury, including kidney fibrosis. Fractalkine/CX3CL1 is a unique chemokine that works as a leukocyte chemoattractant and an adhesion molecule. Recently, fractalkine/CX3CL1 has been reported to promote tissue fibrosis via its cognate receptor, CX3CR1. However, the involvement of the fractalkine-CX3CR1 axis in the pathogenesis of hypertensive ...
Ortega Luis M - - 2011
Hypertension is prevalent in an estimated 29% to 80% of patients treated with peritoneal dialysis (PD). Cardiovascular disease represents the most common cause of mortality in this population, and hypertension (HTN) plays an important role. Volume overload is prevalent in PD patients because of liberal intake of fluids and loss ...
Tank Jens - - 2011
OBJECTIVES: Previous association studies suggested that common polymorphisms of the beta-2 adrenoreceptor gene leading to glycine for arginine substitution at position 16 or glutamic acid for glutamine substitution at position 27 affect blood pressure. We reasoned that measurements of resting sympathetic nerve traffic could increase the sensitivity of defining a ...
Jones Helen - - 2011
Early morning reduction in endothelium-dependent flow-mediated dilation (FMD) may contribute to the high incidence of sudden cardiac death at this time of day. The mechanisms underpinning diurnal variation in FMD are unclear, but potentially relate to a circadian rhythm in sympathetic nerve activity (SNA). We hypothesized that blockade of α(1)- ...
Morris Daniel A - - 2011
BACKGROUND: The authors hypothesized that in patients with heart failure with normal left ventricular (LV) ejection fraction (HFNEF), the same fibrotic processes that affect the subendocardial layer of the left ventricle could also alter the subendocardial fibers of the left atrium. Consequently, these fibrotic alterations, together with chronically elevated LV ...
Kenawey Mohamed - - 2011
PURPOSE: The effect of the rotational alignment of lower extremities on the tibiofemoral contact mechanics is not known. This study was designed to measure the contact area and pressure within medial and lateral tibiofemoral compartments following controlled serial rotational deformities through femoral and tibial shafts. METHODS: Eight lower extremities of ...
Steinback Craig D - - 2011
We investigated the effects of hypocapnia in normal subjects on airway tone while controlling airway cooling and drying. We hypothesized that airway tone is positively related to the degree of hypocapnia. Participants (8; 2 women) underwent 3 protocols consisting of 20min of hyperpnea (breathing frequency=20 breaths min(-1); tidal volume=2.5L) and ...
Leal Viviane O - - 2011
OBJECTIVE: To evaluate muscle function (MF) of patients on hemodialysis (HD) and to investigate the dialysis determinants of maximal voluntary handgrip strength (HGS). METHODS: Forty-three patients on HD (25 men, six diabetics, 54.5 ± 12.2 y of age, 62.2 ± 51.4 mo on dialysis) were studied. HGS was measured three ...
Subramanian Natarajan - - 2011
Raman spectroscopy in laser-heated diamond anvil cells has been employed to probe the bonding state and phase diagram of dense hydrogen up to 140 GPa and 1,500 K. The measurements were made possible as a result of the development of new techniques for containing and probing the hot, dense fluid, ...
Linz Dominik - - 2011
BACKGROUND: Obstructive sleep apnea (OSA) causes negative tracheal pressure (NTP) and is associated with atrial fibrillation (AF). OBJECTIVE: This study aimed to determine the mechanism of atrial electrophysiological changes during tracheal occlusion with or without applied NTP and to evaluate the role of vagal activation, Na(+)/H(+)-exchanger (NHE) and ATP-dependent potassium ...
Leitch Alicea A - - 2011
The bromo-substituted bisdiselenazolyl radical 4b (R(1) = Et, R(2) = Br) is isostructural with the corresponding chloro-derivative 4a (R(1) = Et, R(2) = Cl), both belonging to the tetragonal space group P4̅2(1)m and consisting of slipped π-stack arrays of undimerized radicals. Variable temperature, ambient pressure conductivity measurements indicate a similar ...
Asakura Keisuke - - 2011
Objective: Cutting the intersegmental plane by using a stapler during segmentectomy might interfere with the expansion of the preserved lung due to visceral pleura caught in a staple line, especially in a large regional segmentectomy, such as left upper division or basal segmentectomy. We compared the preserved lung volume after ...
Miyahara Masaaki - - 2011
We report evidence for the natural dissociation of olivine in a shergottite at high-pressure and high-temperature conditions induced by a dynamic event on Mars. Olivine (Fa(34-41)) adjacent to or entrained in the shock melt vein and melt pockets of Martian meteorite olivine-phyric shergottite Dar al Gani 735 dissociated into (Mg,Fe)SiO(3) ...
Shen Guoyin - - 2011
The behavior of volatiles is crucial for understanding the evolution of the Earth's interior, hydrosphere, and atmosphere. Noble gases as neutral species can serve as probes and be used for examining gas solubility in silicate melts and structural responses to any gas inclusion. Here, we report experimental results that reveal ...
Ahart Muhtar - - 2011
The sound velocity in polycrystalline ice was measured as a function of pressure at room temperature to 100 GPa, through the phase field of ice VII and crossing the ice X transition, by Brillouin scattering in order to examine the elasticity, compression mechanism, and structural transitions in this pressure range. ...
Johnson Andrew D AD Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA 01702, - - 2011
We previously conducted genome-wide association meta-analysis of systolic blood pressure, diastolic blood pressure, and hypertension in 29,136 people from 6 cohort studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. Here we examine associations of these traits with 30 gene regions encoding known antihypertensive drug targets. ...
Pizzetti Marianna - - 2011
The microwave-assisted aminocarbonylation of ynamides at low pressures of CO is reported. A new class of (E)-acrylamides that are potentially suitable for several applications has been regioselectively synthesized after microwave irradiation for only 20 min by using eco-friendly [Fe(3) (CO)(12) ] as the catalyst precursor and triethylamine as the ligand. This ...
Wolf Jan Lennard - - 2011
The gas-phase ozonolysis of cyclic-alkenes (1-methyl-cyclohexene, methylene-cyclohexane, α-pinene, β-pinene) is studied with respect to the pressure dependent formation of secondary organic aerosol (SOA). We find that SOA formation is substantially suppressed at lower pressures for all alkenes under study. The suppression coincides with the formation of ketene (α-pinene, 1-methyl-cyclohexene), ethene ...
Kurzydłowski Dominik - - 2011
Recent high-pressure experiments conducted on xenon difluoride (XeF(2)) suggested that this compound undergoes several phase transitions up to 100 GPa, becoming metallic above 70 GPa. In this theoretical study, in contrast to experiment, we find that the ambient pressure molecular structure of xenon difluoride, of I4/mmm symmetry, remains the most ...
Agostoni Piergiuseppe - - 2011
Background. High altitude adaptation leads to progressive increase in arterial PaO(2). In addition to increased ventilation, better arterial oxygenation may reflect improvements in lung gas exchange. Previous investigations reveal alterations at the alveolar-capillary barrier indicative of decreased resistance to gas exchange with prolonged hypoxia adaptation, but how quickly this occurs ...
Bock Jelena - - 2011
In this work, we present a systematic phantom comparison and clinical application of noninvasive pressure difference mapping in the human aorta based on time-resolved 3D phase contrast data. Relative pressure differences were calculated based on integration and iterative refinement of pressure gradients derived from MR-based three-directional velocity vector fields (flow-sensitive ...
Beulen Bart W A M M - - 2011
A new method has been developed to measure local pressure waveforms in large arteries by using ultrasound. The method is based on a simultaneous estimation of distension waveforms and velocity profiles from a single noninvasive perpendicular ultrasound B-mode measurement. Velocity vectors were measured by applying a cross-correlation based technique to ...
Desai Mital - - 2011
BACKGROUND: The aim of this study was to manufacture a new aortic model with physiological properties, which could be used for long-term durability testing of endovascular stent-grafts, as per the recommendations of the Food and Drug Administration. METHODS: Porcine abdominal aortas were acquired to establish values for compliance. The aortic ...
Schmidt J Michael JM Neurological Intensive Care Unit, Department of Neurology, Columbia University Medical Center, and Milstein Hospital, 177 Fort Washington, 8-300, New York, NY 10032, USA. - - 2011
To identify a minimally acceptable cerebral perfusion pressure threshold above which the risks of brain tissue hypoxia (BTH) and oxidative metabolic crisis are reduced for patients with subarachnoid hemorrhage (SAH). We studied 30 poor-grade SAH patients who underwent brain multimodality monitoring (3042 hours). Physiological measures were averaged over 60 minutes ...
Larché J-F - - 2011
The thermoporosimetry method was adapted to determine the mesh size distribution of an acrylate thermoset clearcoat. This goal was achieved by increasing the solvent rate transfer by increasing the pressure and temperature. A comparison of the results obtained using this approach with those obtained by DMA (dynamic mechanical analysis) underlined ...
Khachadorian Sevak - - 2011
We study the high pressure response, up to 8 GPa, of silicon nanowires (SiNWs) with ∼ 15 nm diameter, by Raman spectroscopy. The first order Raman peak shows a superlinear trend, more pronounced compared to bulk Si. Combining transmission electron microscopy and Raman measurements we estimate the SiNWs' bulk modulus and the ...
Ha Kee Soo - - 2011
Obesity during childhood increases the risk of cardiac disease, hypertension, and other complications in adulthood. We investigated the cellular and renin-angiotensin system changes of the heart in obese young rats. We used Sprague-Dawley rats and early obesity was induced by overfeeding through adjusting the number of male pups per dam ...
Yaguchi Toshie - - 2011
An environmental cell for high-temperature, high-resolution transmission electron microscopy of nanomaterials in near atmospheric pressures is developed. The developed environmental cell is a side-entry type with built-in specimen-heating element and micropressure gauge. The relationship between the cell condition and the quality of the transmission electron microscopic (TEM) image and the ...
Yoshimura Yukihiro - - 2011
The high-pressure behavior of H(2)O ice at temperatures below 100 K has been investigated to 20 GPa by Raman spectroscopy. Between 10 and 80 K, high density amorphous (hda) ice formed from ice I(h) undergoes a phase transition near 5 GPa to ice VII' and a transition at 14 GPa ...
Zheng Dingchang - - 2011
A new arterial distensibility measurement technique was assessed in 100 healthy normotensive subjects. Arterial transmural pressures on the whole right arm were reduced with a 50 cm long cuff inflated to 10, 20, 30 and 40 mmHg. The electrocardiogram, and finger and ear photoplethysmograms were recorded simultaneously. Arm pulse propagation ...
Lacy B E - - 2011
Background  Fats cause reflux symptoms in many patients and cholecystokinin (CCK) may play a role. This study was designed to evaluate the effects of intraduodenal nutrient infusion on serum CCK levels, lower esophageal sphincter (LES) pressure, and gastroesophageal reflux (GER). Methods  Twenty-four asymptomatic volunteers were studied. A Dent sleeve catheter ...
Reineke Kai - - 2011
High-pressure thermal sterilization (HPTS) is an emerging technology to produce shelf stable low acid foods. Pressures below 300 MPa can induce spore germination by triggering germination receptors. Pressures above 500 MPa could directly induce a Ca+2-dipicolinic acid (DPA) release, which triggers the cortex-lytic enzymes (CLEs). It has been argued that ...
Desir Gary - - 2011
Renalase is an amine oxidase expressed in kidney, heart, liver, and brain that metabolizes catecholamines. Tissue and plasma levels are decreased in models of hypertension and chronic kidney disease. Its expression is modulated by salt intake, and urinary renalase may regulate catecholamines levels and effect renal sodium and phosphate transport. ...
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