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Results 101 - 150 of 855
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Poeze Martijn - - 2011
Sepsis is accompanied by an increased need for and a decreased supply of arginine, reflecting a condition of arginine deficiency. The objective was to evaluate the effects of l-arginine pretreatment on arginine-nitric oxide (NO) production and hepatosplanchnic perfusion during subsequent endotoxemia. In a randomized controlled trial, pigs (20-25 kg) received ...
Yared Kibar - - 2011
BACKGROUND: Transthoracic echocardiographic estimates of peak systolic pulmonary artery pressure are conventionally calculated from the maximal velocity of the tricuspid regurgitation (TR) jet. Unfortunately, there is insufficient TR to determine estimated peak systolic pulmonary artery pressure (EPSPAP) in a significant number of patients. To date, in the absence of TR, ...
Vo Kevin H - - 2011
OBJECTIVE: To report an incident of rapid development of profound hypotension, differing from the time described in previous reports, during the infusion of rituximab chemotherapy in a patient without prior exposure to the drug. CASE SUMMARY: An 84-year-old white male with Rai stage IV chronic lymphocytic leukemia was prescribed rituximab ...
Møller Søren - - 2011
Background Patients with advanced cirrhosis often develop a hyperdynamic circulation with central hypovolaemia. The events that initiate the systemic haemodynamic abnormalities and the coupling of these factors to splanchnic haemodynamics are still unclear. Objective On the basis of a large population of patients with cirrhosis to identify splanchnic and clinical ...
Wu Yu - - 2011
Cytotoxic T-lymphocyte (CTL) escape mutation is associated with long-term behaviors of human immunodeficiency virus type 1 (HIV-1). Recent studies indicate heterogeneous behaviors of reversible and conservative mutants while the selection pressure changes. The purpose of this study is to optimize the selection pressure to minimize the long-term virus load. The ...
Chen C L - - 2011
Background  Secondary peristalsis is important for the clearance of refluxate or retained food bolus from the esophagus. Mosapride is a prokinetic agent that enhances GI motility by stimulating 5-hydroxytrypatamine(4) (5-HT(4) ) receptors, but its effects on secondary peristalsis are yet unclear in humans. We aimed to investigate the effect of ...
Lambert Elisabeth - - 2011
Ghrelin is a growth hormone-releasing peptide secreted by the stomach with potent effects on appetite. Experimental and clinical studies indicate that ghrelin also influences cardiovascular regulation and metabolic function and mediates behavioral responses to stress. We investigated the effects of ghrelin on blood pressure (BP), sympathetic nervous system activity, and ...
Allen Stephen - - 2011
Introduction and objectives:  There is a need for a measure of airways status that is easier for patients to use. If airflow is briefly occluded at the onset of inspiration the maximum rate of pressure fall, dP/dtmax can be measured. After the occlusion is released, the maximum rate of change ...
Wiesenthal Joshua D - - 2011
OBJECTIVES: To determine the correlation between the renal blood flow (RBF) and tissue oxygenation (PO(2)) at varying intra-abdominal pressures (IAPs) and to compare the effects on renal blood flow from carbon dioxide-induced pneumoperitoneum. METHODS: Carbon dioxide pneumoperitoneum was established in Sprague-Dawley rats (n = 6). Licox oxygen/temperature tissue probes were ...
Bogte A - - 2011
Background  Esophageal high-resolution manometry (HRM) is a novel method for esophageal function testing that has prompted the development of new parameters for quantitative analysis of esophageal function. Until now, the reproducibility of these parameters has not been investigated. Methods  Twenty healthy volunteers underwent HRM on two separate days. Standard HRM ...
Mu ShengYu - - 2011
How high salt intake increases blood pressure is a key question in the study of hypertension. Salt intake induces increased renal sympathetic activity resulting in sodium retention. However, the mechanisms underlying the sympathetic control of renal sodium excretion remain unclear. In this study, we found that β(2)-adrenergic receptor (β(2)AR) stimulation ...
Grøntved Anders - - 2011
OBJECTIVES: In this study we examined the association between leptin and blood pressure in a population-based study of Danish and Norwegian children and adolescents. Because of the putative bidirectional relationship between leptin and adiposity we formally tested (i) the mediating effect of body mass index in the association between leptin ...
May William N - - 2011
To determine the effectiveness of a single radial suture placement in 2 clear corneal incision (CCI) configurations in preventing inflow of bacterial-sized particles. Wilmer Eye Institute, Baltimore, Maryland, USA. Experimental study. Ten human globes were used. Two 25-gauge needles connected to a saline solution bag and to a digital manometer ...
Mandal Dipankar - - 2011
A single stage electrospinning process can give rise to preferentially oriented induced dipoles in poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] nanofibers. The piezoelectricity of as-electrospun P(VDF-TrFE) nanofiber webs opens up new possibilities for their use as a flexible nanogenerators and nano-pressure sensors. In this work, the origin of the piezoelectricity has been spotlighted ...
Liu Rong - - 2011
AIM: The goal of this study was to investigate the association between omentin-1 and carotid atherosclerosis in patients with metabolic syndrome (MetS). METHOD: We enrolled randomly 60 MetS patients, evaluated their carotid atherosclerosis employing ultrasonography and then divided them into two subgroups, MetS with atherosclerosis (MetS+AS) and MetS without atherosclerosis ...
Tousoulis Dimitris - - 2011
BackgroundNitric oxide synthase (NOS) inhibitor asymmetrical dimethylarginine (ADMA) is synthesized by the methylation of arginine as part of the methionine/homocysteine cycle. However, the mechanisms regulating ADMA synthesis in hypertension are unclear.MethodsWe investigated the role of ADMA and antioxidants in endothelial dysfunction during methionine-induced homocysteinemia in hypertensives. Thirty-nine hypertensives and forty-nine ...
Gupta Somesh - - 2011
The authors have indicated no significant interest with commercial supporters.
Odaira Mari - - 2011
BackgroundInteractions among age, arterial stiffness, and pressure wave reflection affect the central blood pressure (CBP). We evaluated our hypothesis that the contribution of the wave reflection to the CBP indexes is reduced at higher levels of arterial stiffness, independent of the effect of age.MethodsIn 2,691 Japanese men aged <60 years ...
Abdel-Hamid Sameh - - 2011
Investigating particle properties such as shape and size is important in understanding the deformation behavior of powder under compression during tableting. Particle shape and size control the pattern of powder rearrangement and interaction in the die and so the final properties of the compact. The aim of this study was ...
Björck Hanna M - - 2011
BackgroundThe functional plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism has previously been associated with hypertension. In recent years, central blood pressure, rather than brachial has been argued a better measure of cardiovascular damage and clinical outcome. The aim of this study was to investigate the possible influence of the 4G/5G polymorphism ...
Urata Jungo - - 2011
Negatively charged low-density lipoprotein (LDL), generated via multiple processes such as oxidation, acetylation, or glycosylation, plays a key role in the initiation and progression of atherosclerosis and related diseases. Anion-exchange high-performance liquid chromatography (AE-HPLC) can subfractionate LDL into LDL-1, LDL-2, and LDL-3 based on LDL particle charge, but the clinical ...
Bharucha Adil E - - 2011
The mechanisms of increased rectal stiffness in women with fecal incontinence (FI) and rectal urgency are not understood. Our hypothesis was that distention-induced activation of mechanosensitive L-type calcium channels in smooth muscle contributes to increased rectal stiffness in FI. Anal pressures, rectal distensibility (compliance, capacity, and contractile response to sinusoidal ...
Cates Matthew J MJ School of Physiology and Pharmacology, Bristol Heart Institute, Medical Sciences Bldg., University of Bristol, Bristol BS8 1TD, - - 2011
There is a strong correlation between increased vertebral artery resistance and arterial blood pressure in humans. The reasons for this increased resistance at high systemic pressure remain unknown, but may include raised sympathetic activity. With the recent finding that prehypertensive spontaneously hypertensive (PHSH) rats, which have raised sympathetic nerve activity, ...
Xue Z Z Department of Pediatrics, H. B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, - - 2011
Previous studies have demonstrated that chronic mechanical strain produced by continuous positive airway pressure (CPAP) reduces in vivo airway reactivity in rabbits and ferrets. For CPAP to potentially have a therapeutic benefit for asthmatic subjects, the reduction in airway responsiveness would need to persist for 12-24 h after its discontinuation, ...
Solozhenko Vladimir L - - 2011
Kinetics of the wurtzite-to-rock-salt transformation in ZnO has been studied in the 5-7 GPa pressure range at temperatures below the activation of diffusion processes. The detailed analysis of non-isothermal experimental data using the general evolution equation describing the kinetics of direct phase transformations in solids allowed us to study the ...
Sankri-Tarbichi Abdul Ghani - - 2011
We hypothesized that hypocapnia is responsible for increased expiratory resistance during NREM sleep. Hypocapnia was induced by hypoxic hyperventilation in 21 subjects (aged 29.4 ± 7.8 yrs, 10 women, BMI 24.4 ± 4.3 kg/m(2)). Isocapnic hypoxia was induced in 12 subjects of whom, 6 underwent hypocapnic hypoxia in the same ...
Sun Bei B Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115 , - - 2011
The renin gene has been previously reported to be associated with essential hypertension in a variety of ethnic groups. However, no studies have systematically evaluated the relationship between single nucleotide polymorphisms (SNPs) representing coverage of the entire renin gene and hypertension risk. To evaluate the association between renin gene variation ...
Ramesh Babu K - - 2011
The structural, electronic, optical, and vibrational properties of LiN(3) under high pressure have been studied using plane wave pseudopotentials within the generalized gradient approximation for the exchange and correlation functional. The calculated lattice parameters agree quite well with experiments. The calculated bulk modulus value is found to be 23.23 GPa, ...
Lee Sung Keun - - 2011
Pressure-induced changes in properties of multicomponent silicate melts in magma oceans controlled chemical differentiation of the silicate earth and the composition of partial melts that might have formed hidden reservoirs. Although melt properties show complex pressure dependences, the melt structures at high pressure and the atomistic origins of these changes ...
Brestak Miroslav - - 2011
OBJECTIVES: This study was designed to compare the first trimester shortening fraction of the right ventricle (SFRV) values between euploid fetuses and fetuses with trisomy 21. METHODS: SFRV was measured in 58 first trimester fetuses between September 2008 and February 2010. The stored M-mode images were used to obtain the ...
Razus D - - 2011
The maximum rates of pressure rise during closed vessel explosions of propane-air mixtures are reported, for systems with various initial concentrations, pressures and temperatures ([C(3)H(8)]=2.50-6.20vol.%, p(0)=0.3-1.3bar; T(0)=298-423K). Experiments were performed in a spherical vessel (Φ=10cm) with central ignition. The deflagration (severity) index K(G), calculated from experimental values of maximum rates ...
Harzali H - - 2011
Power ultrasound is known to enhance crystals nucleation, and nucleation times can be reduced by one up to three orders of magnitude for several organic or inorganic crystals. The precise physics involved in this phenomenon still remains unclear, and various mechanisms involving the action of inertial cavitation bubbles have been ...
Castro Michele M - - 2011
Hypertension is associated with well known structural and functional alterations in both resistance and conduit arteries, which may be the result from long-lasting high blood pressure and may also be the cause of maintained hypertension and its complications. Therefore, in addition to lowering blood pressure, therapeutic strategies targeting the structural ...
Drozd Greg T - - 2011
Ozonolysis is a key reaction in atmospheric chemistry, although important details of the behavior of the ozonolysis intermediates are not known. The key intermediate in ozonolysis, the Criegee intermeiate (CI), is known to quickly isomerize, with the favored unimolecular pathway depending on the relative barriers to isomerization. Stabilized Criegee intermediates ...
Abdel-Hamid Sameh - - 2011
The effect of moisture as a function of water activity (Aw) on the compaction process is important to understand particle/water interaction and deformation. Studying powder/moisture interaction under pressure with radial die-wall pressure (RDWP) tool was never done. The aim of our study was to use this tool to study this ...
Cabadak Hulya - - 2011
Hypertension is a multifactorial disorder that constitutes a major risk factor for the cardiovascular system. Heterotrimeric G-proteins, which couple receptors for diverse extracellular enzymes or ion channels, are correlated with disease mechanisms. Several studies have demonstrated an association between G protein polymorphisms and essential hypertension in some populations, although contradictive ...
Schiller Robert - - 2011
White noise is expected to show up in both pressure and temperature at the nanoscale if linear transport equations prevail. This prediction is based on the thermodynamic fluctuation theory in analogy to a new derivation of the Johnson-Nyquist voltage noise. The pressure noise in liquid filled nanotubes, and temperature noise ...
Goulopoulou S - - 2011
This study tested the hypothesis that limb venous responses to baroreceptor unloading are altered in individuals with high blood pressure (HBP) compared with normotensive (NT) controls. Calf venous compliance was assessed in 20 subjects with prehypertension and stage-1 hypertension (mean arterial pressure, MAP: 104±1 mm Hg) and 13 NT controls (MAP: 86±2 mm Hg) ...
Shea Steven A SA Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA. - - 2011
Blood pressure (BP) usually decreases during nocturnal sleep and increases during daytime activities. Whether the endogenous circadian control system contributes to this daily BP variation has not been determined under appropriately controlled conditions. To determine whether there exists an endogenous circadian rhythm of BP in humans. In 28 normotensive adults ...
Xiaoli Chai - - 2011
Mercury (Hg) distribution and migration in different landfill stabilization processes were evaluated in this study. Wide ranges of Hg concentrations were observed because of the heterogeneity and variability of landfill refuse. In addition, temporally variable conditions, including pH, organic matter, and vegetation cover, which influence Hg migration in landfills, may ...
Yanes Licy L - - 2011
Blood pressure (BP) increases after menopause. However, the mechanisms responsible have not been elucidated. In this study we tested the hypothesis that 20-hydroxyeicosatetraenoic acids (20-HETE), produced by cytochrome P-450 (CYP450) ω-hydroxylase, contributes to the hypertension in a model of postmenopausal hypertension, aged female spontaneously hypertensive rats (PMR). 1-Aminobenzotriazole, a nonselective ...
Kim Jae Hun JH Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA. - - 2011
The pleural surfaces of the lung and chest wall slide against each other with low friction. Normal load support can be effected either by a combination of quasi-static fluid pressure and solid-solid contacts of relatively stiff asperities, or by shear-induced hydrodynamic pressures in the pleural fluid layer. To distinguish between ...
Elfwing Magnus - - 2011
The baroreflex is the main short term compensatory mechanism to buffer blood pressure changes and maintain circulatory homeostasis. Its ontogeny and importance during prenatal life is not fully understood so we used broiler chickens to investigate the maturation of the baroreflex in late incubation using a novel method that measured ...
Vlachos Fotios F Department of Biomedical Engineering, Columbia University, New York 10027, - - 2011
Blood-brain barrier opening using focused ultrasound and microbubbles has been experimentally established as a noninvasive and localized brain drug delivery technique. In this study, the permeability of the opening is assessed in the murine hippocampus after the application of focused ultrasound at three different acoustic pressures and microbubble sizes. Using ...
Wallace Kedra K Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Center for Excellence in Cardiovascular-Renal Research, University of Mississippi Medical Center, 2500 North State St, Jackson, MS 39216-4505, - - 2011
We have shown that hypertension in response to chronic placental ischemia is associated with elevated inflammatory cytokines and CD4(+) T cells. However, it is unknown whether these cells play an important role in mediating hypertension in response to placental ischemia. Therefore, we hypothesize that reduced uterine perfusion pressure (RUPP)-induced CD4(+) ...
Kölegård Roger - - 2011
The objectives were to investigate the effects of repeated increments in local intravascular pressure (pressure training; PT) on (1) distensibility in two arm veins, and (2) pain in the arm induced by markedly increased intravascular pressure. Elevation of venous distending pressure (DP) in an arm was induced by placing the ...
Fahs Christopher A - - 2011
Sudden cardiac events are responsible for 40-50% of line-of-duty firefighter fatalities, yet the exact cause of these events is unknown. Likely, combinations of thermal, physical, and mental factors impair cardiovascular function and trigger such events. Therefore, the purpose of this study was to examine the impact of firefighting activities on ...
Montgomery Jeffrey M - - 2011
We have performed image plate x-ray diffraction studies on a heavy rare earth metal, thulium (Tm), in a diamond anvil cell to a pressure of 195 GPa and volume compression V/V(o) = 0.38 at room temperature. The rare earth crystal structure sequence, [Formula: see text] distorted fcc, is observed in Tm ...
Sudhakar Balasubramanian - - 2011
To determine the effect of combination of edible oils on blood pressure, anthropometric parameters, lipid profile, lipid peroxidative markers, antioxidant status and electrolytes in drug (nifedipine) taking patients with hypertension. In this study, patients were separated into 4 groups. Normal (n=14), hypertensive patients (n=38), 38 patients under medication with nifedipine ...
Lea A S - - 2011
A high-pressure atomic force microscope (AFM) that enables in situ, atomic scale measurements of topography of solid surfaces in contact with supercritical CO(2) (scCO(2)) fluids has been developed. This apparatus overcomes the pressure limitations of the hydrothermal AFM and is designed to handle pressures up to 100 atm at temperatures ...
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