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Results 451 - 500 of 858
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Zhai Yong - - 2011
Pressure perturbation calorimetry (PPC) is a relatively new and efficient technique, to study the volumetric properties of biomolecules in solution. In PPC, the coefficient of thermal expansion of the partial volume of the biomolecule is deduced from the heat consumed or produced after small isothermal pressure jumps (typically±5bar). This strongly ...
Huang Chin-Ming - - 2011
Diagnosis by radial arterial pulse is very important in Traditional Chinese Medicine (TCM). The objective of this study is to evaluate the effects of detection time and position on the parameters of time- and frequency-domain of radial pulse wave and to differentiate between Dyspepsia and Rhinitis by the statistical analysis ...
Nishyama Michiko - - 2011
We describe respiration monitoring in sleep using hetero-core fiber optic pressure sensors. The proposed hetero-core fiber optic sensor is highly sensitive to macrobending as a result of the core diameter difference due to stable single-mode transmission. Pressure sensors based on hetero-core fiber optics were fabricated to have a high sensitivity ...
Benetti Thaís Helena - - 2011
Intestinal constipation--a common symptom among the general population--is more frequent in women. It may be secondary to an improper diet or organic or functional disturbances, such as dyskinesia of the pelvic floor. This is basically characterized by the absence of relaxation or paradoxical contraction of the pelvic floor and anal ...
Andersson Kennet - - 2011
A lumbar infusion test is commonly used as a predictive test for patients with normal pressure hydrocephalus and for evaluation of cerebrospinal fluid (CSF) shunt function. Different infusion protocols can be used to estimate the outflow conductance (Cout) or its reciprocal the outflow resistance (Rout), with or without using the ...
Schiffl Helmut - - 2011
Primary hyperparathyroidism (PHPT) may be associated with arterial hypertension. The underlying mechanisms are not fully understood and reversibility by parathyroid surgery is controversial. This study aimed to characterize pressor hormones, vascular reactivity to norepinephrine, and cytosolic-free calcium in platelets in 15 hypertensive patients with hypercalcaemic PHPT before and after successful ...
Gupta Vibhanshu - - 2011
The objective of this study was to assess the various factors affecting endothelial function in essential hypertensives and to establish a relation between them in a regression model. Also, the micro-inflammatory state that is known to exist in essential hypertension was evaluated. Sixty newly detected patients of essential hypertension not ...
Bell M - - 2011
Low arterial oxygen saturation (SaO(2)) will result in a reduced rate of arterial oxygen delivery to the tissues (DO(2)), unless there is a compensatory increase in cardiac output (CO) or haemoglobin concentration (Hb). An adequate DO(2) can therefore be maintained by increasing ventilation, CO, or both. Sustaining a tissue specific ...
Shih Chih-Hsin - - 2011
This study presents a novel approach to decant supernatant on a centrifugal platform. By manipulating the centrifugally induced pressure and the elastic deformation of the plastic lids in the decanting chamber, fixed amounts of the supernatant can be decanted into the detection chamber at lower rotational speeds. The experimental results ...
Golzan S Mojtaba - - 2011
Purpose: The amplitude of spontaneous retinal venous pulsations (SRVP) is known to be affected by intraocular pressure (IOP), retinal venous pressure, and intracranial pressure (ICP). This study characterized SRVPs adjacent to the disc and quantified changes in the amplitude of these pulsations during IOP manipulation in normal subjects. Methods: The ...
Valenti V E - - 2011
In this study the baroreflex sensitivity of conscious, juvenile, spontaneously hypertensive rats (SHRs) was compared. The study population consisted of 19 eight-week-old male SHRs. The baroreflex sensitivity was quantified as the derivative of the variation in heart rate (HR) and the variation of mean arterial pressure (baroreflex sensitivity = ΔHR/ΔMAP). ...
Minegishi Sachito - - 2011
Although pressure-overload right ventricular hypertrophy is a long-term risk in some congenital heart diseases such as tetralogy of Fallot, how it develops is unclear. The aim of this study was to investigate the mechanism of development of this right ventricular heart failure.Pulmonary artery banding in 10-day-old rabbits induced pressure-overload right ...
Tanaka Yoshifumi - - 2011
The 1st purpose of this study was to examine multiple electromyography (EMG) during voluntary hand movements. A secondary purpose was to investigate possible effects of pressure on intracortical inhibition (ICI) and intracortical facilitation (ICF) functions of the motor cortex, using paired-pulse transcranial magnetic stimulation. Twelve participants traced a 15-cm diameter ...
Baruch Martin C - - 2011
Markers of temporal changes in central blood volume are required to non-invasively detect hemorrhage and the onset of hemorrhagic shock. Recent work suggests that pulse pressure may be such a marker. A new approach to tracking blood pressure, and pulse pressure specifically is presented that is based on a new ...
Bellapart Judith - - 2011
The insertion of Ventricular Assist Devices is a common strategy for cardiovascular support in patients with refractory cardiogenic shock. This study sought to determine the impact of ventricular assist devices on the dynamic relationship between arterial blood pressure and cerebral blood flow velocity. A sample of 5 patients supported with ...
Kwon S T - - 2011
In this paper, we review existing clinical research data on post-endovascular repair (EVAR) intrasac pressure and relation with abdominal aortic aneurysm (AAA) size changes. Based on the review, we hypothesize that intrasac pressure has a significant impact on post-EVAR AAA size changes, and post-EVAR remodeling depends also on how the ...
Schultz David M - - 2011
Several animal and clinical studies have shown that thoracic spinal cord stimulation (SCS) may decrease mean arterial pressure (MAP). A previous study in normotensive participants demonstrated a small reduction in MAP during SCS at the T5-T6 spinal level. It has also been demonstrated that chronic SCS at the subthreshold stimulation ...
Yamada Akihiro - - 2011
An experimental setup for high-pressure liquid structure studies with synchrotron x-ray diffraction using the Paris-Edinburgh press has been installed at station 16-BM-B (HPCAT) of the Advanced Photon Source, Argonne National Laboratory. By collecting energy-dispersive data with a synchrotron white beam at various 2θ angles, the present device allows us to ...
Lin Rong - - 2011
Many studies have suggested that heme oxygenase-1 (HMOX1) might be implicated in blood pressure (BP) regulation. We hypothesized that this gene might be responsible for the variation of susceptibility to essential hypertension (EH) and BP and investigated three polymorphisms in HMOX1 (i.e., the (GT)n repeat in the HMOX1 promoter and ...
Wang Zhigang - - 2011
A broadband spectroscopy method is proposed to measure the ultrasonic wave phase velocity of Z-cut quartz under high pressure up to 4.7 GPa. The sample is in a hydrostatic circumstance under high pressure, and we can get longitudinal wave and shear wave signals simultaneously in our work. By fast Fourier ...
He Chunyuan - - 2011
A microcircuit was designed and fabricated on a diamond anvil cell for alternating current impedance spectroscopy measurement under high pressure. Sputtered molybdenum film on a diamond anvil was used as an electrode, maintained the contact between the sample and the electrode stable, and reduced the electrode effect on the impedance ...
Moret Karin E - - 2011
In this study, variations in plasma conductivity (PC), as a surrogate marker of plasma sodium, as well as its relation with intradialytic ionic mass balance (IMB) and blood pressure were assessed in 73 patients. Plasma conductivity and IMB were retrieved on a treatment to treatment basis during a 6-month period. ...
Heffernan Kevin S - - 2011
We evaluated the effect of atenolol vs metoprolol succinate on vascular function in patients with essential hypertension. Given intrinsic differences between these agents, we hypothesized that atenolol and metoprolol succinate would have disparate effects on vascular function. This study included 24 patients with hypertension (age 56 ± 2 years, 8 ...
Abolghasmi Rozita - - 2011
To determine the antihypertensive benefit of adding low dose sprinolactone to multi-drug regimens that included a diuretic, a calcium channel blocker and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in patients with moderately severe chronic kidney disease (CKD) [glomerular filtration rate (GFR) 25-50 mL/min] and resistant hyper-tension, we studied 41 ...
Norii Tatsuya - - 2011
Splenic infarction in individuals harboring the sickle cell trait can occur in the setting of exposure to low oxygen tension at high altitudes. While this is a concern in unpressurized aircraft flight, it has not been well documented in pressurized flight. What has not been addressed is whether this relative ...
McGill Robert - - 2011
Recent wartime contingencies have demanded frequent aeromedical evacuation of polytrauma patients, all with risk factors for the development of compartment syndrome. This study investigated the effect of altitude on the pressure in uninjured myofascial compartments of 10 pigs as part of a program with the ultimate goal of determining the ...
Tycinska A M - - 2011
Clinical relevance of relations among blood pressure (BP), inflammation, endothelial dysfunction and sympathetic activation is unknown. Study aimed, whether in patients with diagnosed and treated essential arterial hypertension (HTN) biomarkers of inflammation (hs-C-reactive protein, hs-CRP), endothelial dysfunction (endothelin-1, ET-1), and sympathetic nervous system modulation (epinephrine, E and norepinephrine, NE) could ...
Mitchell Ryan T M - - 2011
The purpose of this study is to determine the lowest concentration of subcutaneous phenylephrine (neosynephrine) required for effective vasoconstriction in skin graft donor sites. Surgery for burn injury is associated with blood loss. Tourniquet use and tumescence with epinephrine have decreased blood loss. However, absorption of epinephrine has been reported ...
Kim Hye Young - - 2011
Reparixin, an inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation, has been shown to attenuate inflammatory responses in various injury models. In the present study, the hypertension-related functional roles of reparixin were examined in hypertensive animals. Spontaneously hypertensive rats (SHR) at the age of 18 weeks were administered a subcutaneous ...
Yamashita K - - 2011
Sperm are affected by physical conditions, such as centrifugation and temperature. The objective of this study was to examine the effect of a low atmospheric pressure on viability and capacitation status of boar sperm during semen preservation at room temperature. Sperm-rich fraction from Berkshire boars was diluted at cellsmL(-1) with ...
Cohen Benjamin - - 2011
Diagnosis and treatment of hydrocephalus is hindered by a lack of systemic understanding of the interrelationships between pressures and flow of cerebrospinal fluid in the brain. Control volume analysis provides a fluid physics approach to quantify and relate pressure and flow information. The objective of this study was to use ...
Huo Ming-Ming - - 2011
The Raman spectra of all-trans-lycopene in n-hexane were measured under high pressure, and the results compared with those of β-carotene. The different pressure effects on Raman spectra are analyzed taking into account the different structures of lycopene and β-carotene molecules. It is concluded that: (a) the vibronic coupling between the ...
Rattan S - - 2011
Maintenance of the basal tone in the internal anal sphincter (IAS) is critical for rectoanal continence. Effective evacuation requires a fully functional rectoanal inhibitory reflex (RAIR)-mediated relaxation of the IAS via inhibitory neurotransmission (INT). Systematic studies examining the nature of the INT in different species have identified nitric oxide (NO) ...
Pang M - - 2011
A polarization controller was built by pressurizing laterally three segments of a commercial hollow-core photonic bandgap fiber. By varying the magnitudes of the applied pressures, the output state of polarization showed a good coverage of all the possible polarization states on the surface of the Poincaré sphere.
Hlebowicz Joanna - - 2011
The digestion of food is known to alter the hemodynamics of the body significantly. The purpose of this study was to study the postprandial changes in stroke volume (SV), cardiac output (CO) and left ventricular (LV) longitudinal systolic and diastolic functions measured with tissue Doppler imaging, in relation to gastric ...
Gabutti Luca - - 2011
A rapid decrease of serum potassium concentrations during haemodialysis produces a significant increase in blood pressure parameters at the end of the session, even if effects on intra-dialysis pressure are not seen. Paradoxically, in animal models potassium is a vasodilator and decreases myocardial contractility. The purpose of this trial is ...
Payen Didier - - 2011
Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive to invasive, delivering various parameters related to ...
Kent Shia T - - 2011
Evidence is mounting regarding the clinically significant effect of temperature on blood pressure. In this cross-sectional study the authors obtained minimum and maximum temperatures and their respective previous week variances at the geographic locations of the self-reported residences of 26,018 participants from a national cohort of blacks and whites, aged ...
Tank Jens - - 2011
Ozone concentrations in ambient air are related to cardiopulmonary perturbations in the aging population. Increased central sympathetic nerve activity induced by local airway inflammation may be one possible mechanism. To elucidate this issue further, we performed a randomized, double-blind, cross-over study, including 14 healthy subjects (3 females, age 22-47 years), ...
Seifert John G - - 2011
Confusion and controversy exist regarding the cardiovascular effects of dietary supplements containing caffeine and Citrus aurantium (bitter orange) extract. The primary protoalkaloidal ingredient in bitter orange extract is p-synephrine which has some structural similarities to ephedrine and nor-epinephrine, but exhibits markedly different pharmacokinetic and receptor binding properties. The goal of ...
Bertram C D - - 2011
The aim of this investigation was to achieve the first step toward a comprehensive model of the lymphatic system. A numerical model has been constructed of a lymphatic vessel, consisting of a short series chain of contractile segments (lymphangions) and of intersegmental valves. The changing diameter of a segment governs ...
Torrentino-Madamet Marylin - - 2011
Over its life cycle, the Plasmodium falciparum parasite is exposed to different environmental conditions, particularly to variations in O2 pressure. For example, the parasite circulates in human venous blood at 5% O2 pressure and in arterial blood, particularly in the lungs, at 13% O2 pressure. Moreover, the parasite is exposed ...
Zacharopoulou Ioanna - - 2011
The ratio of early diastolic transmitral velocity to early mitral annular diastolic velocity (E/Ea) can be used to group patients according to filling pressures. However this relationship has not been validated in the intermediate group (E/Ea = 8-15). The time difference between the onset of E and Ea also correlates ...
Thadhani Ravi R Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, USA. - - 2011
In chronic kidney disease (CKD), left ventricular hypertrophy (LVH) is prevalent and is associated with increased cardiovascular morbidity and mortality. Vitamin D receptor (VDR) activation attenuates LVH progression in animal models. PRIMO is a multinational, randomized, double-blinded trial with oral paricalcitol in subjects with stages 3-4 CKD, mild-to-moderate LVH and ...
Chang Gordon Y GY Bryn Mawr Hospital, Bryn Mawr, PA, USA. - - 2011
Delivery of warm, humidified, supplemental oxygen via high-flow nasal cannula has several potential benefits; however, the high-flow range may not maintain humidification and temperature and in some cases may cause excessive expiratory pressure loading. To compare the effect of flow on temperature, humidity, pressure, and resistance in nasal cannula (NC), ...
Lobmeyer Maximilian T MT Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, Florida 32610, - - 2011
The G-protein-coupled receptor kinases (GRKs) GRK2 and GRK5 are important regulators of β-adrenergic signaling. This study characterized single-nucleotide polymorphisms (SNPs) in the GRK2 gene (ADRBK1) and determined if these and a GRK5 Gln41Leu polymorphism affect the blood pressure (BP) response to atenolol or hydrochlorothiazide or adverse cardiovascular outcomes in hypertensives. ...
Kanbay Mehmet M Division of Nephrology, Department of Internal Medicine, Fatih University School of Medicine, Ankara, - - 2011
Investigation into the underlying mechanisms of salt sensitivity has made important advances in recent years. This review examines in particular the effects of sodium and potassium on vascular function. Sodium chloride (salt) intake promotes cutaneous lymphangiogenesis mediated through tissue macrophages and directly alters endothelial cell function, promoting increased production of ...
Humphreys Michael H MH Division of Nephrology, San Francisco General Hospital and Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA. - - 2011
Melanocortins (MSH's) are three structurally related peptides derived from proopiomelanocortin. They regulate several physiologic functions including energy metabolism, appetite, and inflammation. Recent work in rodents has also identified important effects of MSH's, particularly γ-MSH, on sodium metabolism and blood pressure regulation. Normal rats and mice respond to a high sodium ...
Diaz Keith M KM Hypertension, Molecular and Applied Physiology Laboratory, Department of Kinesiology, College of Health Professions, Temple University, Philadelphia, PA 19122, - - 2011
We investigated the relationship between renal function, blood pressure variability (BPV), and nitric oxide (NO) in a group of African Americans with normal or mildly impaired renal function. 24-hour ambulatory blood pressure monitoring was performed, NO measured, and glomerular filtration rate (GFR) calculated in 38 African Americans. Participants were categorized ...
Albinsson Sebastian S Department of Pharmacology, Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, Connecticut, United States of - - 2011
Phenotypic modulation of smooth muscle cells (SMCs) plays a key role in vascular disease, including atherosclerosis. Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown. Recent reports suggest that specific microRNAs (miRNAs) are involved in SMC differentiation and vascular disease but ...
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