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Bellapart Judith - - 2011
The insertion of Ventricular Assist Devices is a common strategy for cardiovascular support in patients with refractory cardiogenic shock. This study sought to determine the impact of ventricular assist devices on the dynamic relationship between arterial blood pressure and cerebral blood flow velocity. A sample of 5 patients supported with ...
Kwon S T - - 2011
In this paper, we review existing clinical research data on post-endovascular repair (EVAR) intrasac pressure and relation with abdominal aortic aneurysm (AAA) size changes. Based on the review, we hypothesize that intrasac pressure has a significant impact on post-EVAR AAA size changes, and post-EVAR remodeling depends also on how the ...
Schultz David M - - 2011
Several animal and clinical studies have shown that thoracic spinal cord stimulation (SCS) may decrease mean arterial pressure (MAP). A previous study in normotensive participants demonstrated a small reduction in MAP during SCS at the T5-T6 spinal level. It has also been demonstrated that chronic SCS at the subthreshold stimulation ...
Yamada Akihiro - - 2011
An experimental setup for high-pressure liquid structure studies with synchrotron x-ray diffraction using the Paris-Edinburgh press has been installed at station 16-BM-B (HPCAT) of the Advanced Photon Source, Argonne National Laboratory. By collecting energy-dispersive data with a synchrotron white beam at various 2θ angles, the present device allows us to ...
Lin Rong - - 2011
Many studies have suggested that heme oxygenase-1 (HMOX1) might be implicated in blood pressure (BP) regulation. We hypothesized that this gene might be responsible for the variation of susceptibility to essential hypertension (EH) and BP and investigated three polymorphisms in HMOX1 (i.e., the (GT)n repeat in the HMOX1 promoter and ...
Wang Zhigang - - 2011
A broadband spectroscopy method is proposed to measure the ultrasonic wave phase velocity of Z-cut quartz under high pressure up to 4.7 GPa. The sample is in a hydrostatic circumstance under high pressure, and we can get longitudinal wave and shear wave signals simultaneously in our work. By fast Fourier ...
He Chunyuan - - 2011
A microcircuit was designed and fabricated on a diamond anvil cell for alternating current impedance spectroscopy measurement under high pressure. Sputtered molybdenum film on a diamond anvil was used as an electrode, maintained the contact between the sample and the electrode stable, and reduced the electrode effect on the impedance ...
Moret Karin E - - 2011
In this study, variations in plasma conductivity (PC), as a surrogate marker of plasma sodium, as well as its relation with intradialytic ionic mass balance (IMB) and blood pressure were assessed in 73 patients. Plasma conductivity and IMB were retrieved on a treatment to treatment basis during a 6-month period. ...
Heffernan Kevin S - - 2011
We evaluated the effect of atenolol vs metoprolol succinate on vascular function in patients with essential hypertension. Given intrinsic differences between these agents, we hypothesized that atenolol and metoprolol succinate would have disparate effects on vascular function. This study included 24 patients with hypertension (age 56 ± 2 years, 8 ...
Abolghasmi Rozita - - 2011
To determine the antihypertensive benefit of adding low dose sprinolactone to multi-drug regimens that included a diuretic, a calcium channel blocker and angiotensin-converting enzyme inhibitor or angiotensin receptor blocker in patients with moderately severe chronic kidney disease (CKD) [glomerular filtration rate (GFR) 25-50 mL/min] and resistant hyper-tension, we studied 41 ...
Norii Tatsuya - - 2011
Splenic infarction in individuals harboring the sickle cell trait can occur in the setting of exposure to low oxygen tension at high altitudes. While this is a concern in unpressurized aircraft flight, it has not been well documented in pressurized flight. What has not been addressed is whether this relative ...
McGill Robert - - 2011
Recent wartime contingencies have demanded frequent aeromedical evacuation of polytrauma patients, all with risk factors for the development of compartment syndrome. This study investigated the effect of altitude on the pressure in uninjured myofascial compartments of 10 pigs as part of a program with the ultimate goal of determining the ...
Tycinska A M - - 2011
Clinical relevance of relations among blood pressure (BP), inflammation, endothelial dysfunction and sympathetic activation is unknown. Study aimed, whether in patients with diagnosed and treated essential arterial hypertension (HTN) biomarkers of inflammation (hs-C-reactive protein, hs-CRP), endothelial dysfunction (endothelin-1, ET-1), and sympathetic nervous system modulation (epinephrine, E and norepinephrine, NE) could ...
Mitchell Ryan T M - - 2011
The purpose of this study is to determine the lowest concentration of subcutaneous phenylephrine (neosynephrine) required for effective vasoconstriction in skin graft donor sites. Surgery for burn injury is associated with blood loss. Tourniquet use and tumescence with epinephrine have decreased blood loss. However, absorption of epinephrine has been reported ...
Kim Hye Young - - 2011
Reparixin, an inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation, has been shown to attenuate inflammatory responses in various injury models. In the present study, the hypertension-related functional roles of reparixin were examined in hypertensive animals. Spontaneously hypertensive rats (SHR) at the age of 18 weeks were administered a subcutaneous ...
Yamashita K - - 2011
Sperm are affected by physical conditions, such as centrifugation and temperature. The objective of this study was to examine the effect of a low atmospheric pressure on viability and capacitation status of boar sperm during semen preservation at room temperature. Sperm-rich fraction from Berkshire boars was diluted at cellsmL(-1) with ...
Diaz Keith M - - 2011
We investigated the relationship between renal function, blood pressure variability (BPV), and nitric oxide (NO) in a group of African Americans with normal or mildly impaired renal function. 24-hour ambulatory blood pressure monitoring was performed, NO measured, and glomerular filtration rate (GFR) calculated in 38 African Americans. Participants were categorized ...
Cohen Benjamin - - 2011
Diagnosis and treatment of hydrocephalus is hindered by a lack of systemic understanding of the interrelationships between pressures and flow of cerebrospinal fluid in the brain. Control volume analysis provides a fluid physics approach to quantify and relate pressure and flow information. The objective of this study was to use ...
Huo Ming-Ming - - 2011
The Raman spectra of all-trans-lycopene in n-hexane were measured under high pressure, and the results compared with those of β-carotene. The different pressure effects on Raman spectra are analyzed taking into account the different structures of lycopene and β-carotene molecules. It is concluded that: (a) the vibronic coupling between the ...
Rattan S - - 2011
Maintenance of the basal tone in the internal anal sphincter (IAS) is critical for rectoanal continence. Effective evacuation requires a fully functional rectoanal inhibitory reflex (RAIR)-mediated relaxation of the IAS via inhibitory neurotransmission (INT). Systematic studies examining the nature of the INT in different species have identified nitric oxide (NO) ...
Pang M - - 2011
A polarization controller was built by pressurizing laterally three segments of a commercial hollow-core photonic bandgap fiber. By varying the magnitudes of the applied pressures, the output state of polarization showed a good coverage of all the possible polarization states on the surface of the Poincaré sphere.
Hlebowicz Joanna - - 2011
The digestion of food is known to alter the hemodynamics of the body significantly. The purpose of this study was to study the postprandial changes in stroke volume (SV), cardiac output (CO) and left ventricular (LV) longitudinal systolic and diastolic functions measured with tissue Doppler imaging, in relation to gastric ...
Gabutti Luca - - 2011
A rapid decrease of serum potassium concentrations during haemodialysis produces a significant increase in blood pressure parameters at the end of the session, even if effects on intra-dialysis pressure are not seen. Paradoxically, in animal models potassium is a vasodilator and decreases myocardial contractility. The purpose of this trial is ...
Payen Didier - - 2011
Fluid resuscitation is a cornerstone of intensive care unit patient care, but prediction of the cardiovascular response remains difficult, despite many efforts in clinical research. The concept of responders and nonresponders illustrates such a difficulty. Many techniques have been tested, from strictly non-invasive to invasive, delivering various parameters related to ...
Kent Shia T - - 2011
Evidence is mounting regarding the clinically significant effect of temperature on blood pressure. In this cross-sectional study the authors obtained minimum and maximum temperatures and their respective previous week variances at the geographic locations of the self-reported residences of 26,018 participants from a national cohort of blacks and whites, aged ...
Tank Jens - - 2011
Ozone concentrations in ambient air are related to cardiopulmonary perturbations in the aging population. Increased central sympathetic nerve activity induced by local airway inflammation may be one possible mechanism. To elucidate this issue further, we performed a randomized, double-blind, cross-over study, including 14 healthy subjects (3 females, age 22-47 years), ...
Seifert John G - - 2011
Confusion and controversy exist regarding the cardiovascular effects of dietary supplements containing caffeine and Citrus aurantium (bitter orange) extract. The primary protoalkaloidal ingredient in bitter orange extract is p-synephrine which has some structural similarities to ephedrine and nor-epinephrine, but exhibits markedly different pharmacokinetic and receptor binding properties. The goal of ...
Albinsson Sebastian - - 2011
Phenotypic modulation of smooth muscle cells (SMCs) plays a key role in vascular disease, including atherosclerosis. Several transcription factors have been suggested to regulate phenotypic modulation of SMCs but the decisive mechanisms remain unknown. Recent reports suggest that specific microRNAs (miRNAs) are involved in SMC differentiation and vascular disease but ...
Bertram C D - - 2011
The aim of this investigation was to achieve the first step toward a comprehensive model of the lymphatic system. A numerical model has been constructed of a lymphatic vessel, consisting of a short series chain of contractile segments (lymphangions) and of intersegmental valves. The changing diameter of a segment governs ...
Humphreys Michael H - - 2011
Melanocortins (MSH's) are three structurally related peptides derived from proopiomelanocortin. They regulate several physiologic functions including energy metabolism, appetite, and inflammation. Recent work in rodents has also identified important effects of MSH's, particularly γ-MSH, on sodium metabolism and blood pressure regulation. Normal rats and mice respond to a high sodium ...
Kanbay Mehmet - - 2011
Investigation into the underlying mechanisms of salt sensitivity has made important advances in recent years. This review examines in particular the effects of sodium and potassium on vascular function. Sodium chloride (salt) intake promotes cutaneous lymphangiogenesis mediated through tissue macrophages and directly alters endothelial cell function, promoting increased production of ...
Torrentino-Madamet Marylin - - 2011
Over its life cycle, the Plasmodium falciparum parasite is exposed to different environmental conditions, particularly to variations in O2 pressure. For example, the parasite circulates in human venous blood at 5% O2 pressure and in arterial blood, particularly in the lungs, at 13% O2 pressure. Moreover, the parasite is exposed ...
Lobmeyer Maximilian T - - 2011
The G-protein-coupled receptor kinases (GRKs) GRK2 and GRK5 are important regulators of β-adrenergic signaling. This study characterized single-nucleotide polymorphisms (SNPs) in the GRK2 gene (ADRBK1) and determined if these and a GRK5 Gln41Leu polymorphism affect the blood pressure (BP) response to atenolol or hydrochlorothiazide or adverse cardiovascular outcomes in hypertensives. ...
Zacharopoulou Ioanna - - 2011
The ratio of early diastolic transmitral velocity to early mitral annular diastolic velocity (E/Ea) can be used to group patients according to filling pressures. However this relationship has not been validated in the intermediate group (E/Ea = 8-15). The time difference between the onset of E and Ea also correlates ...
Thadhani Ravi R Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, USA. - - 2011
In chronic kidney disease (CKD), left ventricular hypertrophy (LVH) is prevalent and is associated with increased cardiovascular morbidity and mortality. Vitamin D receptor (VDR) activation attenuates LVH progression in animal models. PRIMO is a multinational, randomized, double-blinded trial with oral paricalcitol in subjects with stages 3-4 CKD, mild-to-moderate LVH and ...
Chang Gordon Y GY Bryn Mawr Hospital, Bryn Mawr, PA, USA. - - 2011
Delivery of warm, humidified, supplemental oxygen via high-flow nasal cannula has several potential benefits; however, the high-flow range may not maintain humidification and temperature and in some cases may cause excessive expiratory pressure loading. To compare the effect of flow on temperature, humidity, pressure, and resistance in nasal cannula (NC), ...
Suslick Kenneth S - - 2010
We review recent work on the use of sonoluminescence (SL) to probe spectroscopically the conditions created during cavitation, both in clouds of collapsing bubbles (multibubble sonoluminescence, (MBSL)) and in single bubble events. The effective MBSL temperature can be controlled by the vapor pressure of the liquid or the thermal conductivity ...
Ravi Pasupala - - 2011
We have explored the geometric and electronic structures, band gap, thermodynamic properties, density, detonation velocity and detonation pressure of aminopolynitropyrazoles using the density functional theory (DFT) at the B3LYP/aug-cc-pVDZ level. The calculated detonation velocity and detonation pressure, stability and sensitivity of model compounds appear to be promising compared to the ...
Chen Rong - - 2011
Enhanced hydrostatic pressure can induce phase transitions in hydrated lipid bilayers especially those composed of saturated phospholipids. In this work, the phase behavior of fully hydrated DPPC (1,2-dipalmitoyl-sn-glycero-3-phosphocholine) and POPC (2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine) bilayers as a function of pressure up to 3000 atm has been examined in atomic detail on time scales ...
Yang Lei - - 2010
In situ observations of evaporation-induced colloidal self-assembly and in situ measurement of mass transfer process were carried out under a temperature and pressure controlling system. The growth processes of colloidal crystals in different cuvettes recorded by direct video observations revealed that solvent flow around the pore space of the crystal ...
Dinning Philip G - - 2010
Background: Intraluminal manometry is a tool commonly used to record motility in the human digestive tract. The recorded signal results from a combination of factors including the hydrodynamic pressure transmitted through the intestinal contents due to the contraction of the gut wall and the force of the gut wall acting ...
Jiang Jyh-Chiang - - 2011
We have investigated the effect of pressure on imidazolium C-H---O interactions in 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide (EMI(+)TFSA(-))/L64 and EMI(+)TFSA(-)/1,4-dioxane mixtures. The addition of Pluronic L64 to EMI(+)TFSA(-) leads to appreciable changes in band frequencies and shapes of the imidazolium C-H stretching bands. A possible explanation is the formation of C-H---O interactions between ...
Janssen P - - 2010
Background  Serotonin is believed to be involved in the regulation of the gastric accommodation reflex in man however which receptor subtype(s) are involved remains to be elucidated. Methods  Eleven healthy subjects (nine men, age 19-30) underwent a gastric barostat and a drinking test after treatment with either placebo or ondansetron ...
Chen Jing J Department of Mathematics, Duke University, Durham, North Carolina; and State University of New York, Stony Brook, New York, - - 2011
Elevations in systolic blood pressure are believed to be closely linked to the pathogenesis and progression of renal diseases. It has been hypothesized that the afferent arteriole (AA) protects the glomerulus from the damaging effects of hypertension by sensing increases in systolic blood pressure and responding with a compensatory vasoconstriction ...
Verstraeten M - - 2011
We report on a first series of experiments comparing the selectivity and the kinetic performance of constant flow rate and constant pressure mode gradient elution separations. Both water-methanol and water-acetonitrile mobile phase mixtures have been considered, as well as different samples and gradient programs. Instrument pressures up to 1200bar have ...
Keenan Derek F - - 2011
The aim of the present study was the evaluation of high hydrostatic pressure (HHP) processing on the levels of polyphenolic compounds and selected quality attributes of fruit smoothies compared to fresh and mild conventional pasteurization processing. Fruit smoothie samples were thermally (P(70) > 10 min) or HHP processed (450 MPa/1, ...
Broeckhoven K - - 2011
We report on a general theoretical assessment of the potential kinetic advantages of running LC gradient elution separations in the constant-pressure mode instead of in the customarily used constant-flow rate mode. Analytical calculations as well as numerical simulation results are presented. It is shown that, provided both modes are run ...
Jones Travis E - - 2010
We predict a quantum phase transition in fcc Ca under hydrostatic pressure. Using density functional theory, we find, at pressures below 80 kbar, the topology of the electron charge density is characterized by nearest neighbor atoms connected through bifurcated bond paths and deep minima in the octahedral holes. At pressures ...
Lei Jilin - - 2011
In order to investigate the effects ethanol-diesel blends and altitude on the performance and emissions of diesel engine, the comparative experiments were carried out on the bench of turbo-charged diesel engine fueled with pure diesel (as prototype) and ethanol-diesel blends (E10, E15, E20 and E30) under different atmospheric pressures (81 ...
Rausch M K - - 2011
We introduce a novel constitutive model for growing soft biological tissue and study its performance in two characteristic cases of mechanically induced wall thickening of the heart. We adopt the concept of an incompatible growth configuration introducing the multiplicative decomposition of the deformation gradient into an elastic and a growth ...
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