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Carja Oana O Department of Biology, Stanford University, Stanford, CA, USA ocarja@stanford.edu - - 2014
Stochastic switching is an example of phenotypic bet hedging, where an individual can switch between different phenotypic states in a fluctuating environment. Although the evolution of stochastic switching has been studied when the environment varies temporally, there has been little theoretical work on the evolution of phenotypic switching under both ...
Wininger Michael M Department of Veterans Affairs, Cooperative Studies Program , West Haven, CT , USA - - 2014
Abstract Purpose: The common responses to pressure sensor saturation are extreme: either discarding of data, or wholesale alteration of experimental protocol. Here, we test four simplistic strategies for restoring missing data due to sensor saturation, avoiding such drastic measures. Methods: We tested these algorithms on 62 pressure maps collected from ...
Rihar Andra - - 2014
Existing motor pattern assessment methods, such as digital cameras and optoelectronic systems, suffer from object obstruction and require complex setups. To overcome these drawbacks, this paper presents a novel approach for biomechanical evaluation of newborn motor skills development. Multi-sensor measurement system comprising pressure mattress and IMUs fixed on trunk and ...
Chappell Daniel D Department of Anaesthesiology, University Hospital Munich, Nussbaumstrasse 20, 80336 Munich, - - 2014
Intravenous fluid therapy and perception of volume effects are often misunderstood. The pharmacokinetical difference between colloids and crystalloids depends on the condition of the vascular permeability barrier. Its functioning is still largely based on Starling's principle from 1896, realising that transport of fluid to and from the interstitial space follows ...
Nikoletou Dimitra D Division of Asthma, Allergy and Lung Biology, King's College London, London, - - 2014
Background: Sniff nasal inspiratory pressure (SNIP) is a non-invasive measure of inspiratory muscle function often used as an outcome measure in clinical studies. An initial period of familiarisation with the test is recommended to minimise the learning effect. The repeatability of SNIP in patients with chronic obstructive pulmonary disease (COPD) ...
Selwood Katherine E KE School of Biological Sciences, Monash University, Clayton, Victoria, 3800, - - 2014
Understanding the processes that lead to species extinctions is vital for lessening pressures on biodiversity. While species diversity, presence and abundance are most commonly used to measure the effects of human pressures, demographic responses give a more proximal indication of how pressures affect population viability and contribute to extinction risk. ...
Schuster Alexander Karl-Georg AK Medical Faculty Mannheim, Mannheim Institute of Public Health, Social and Preventive Medicine, Heidelberg University, Mannheim, - - 2014
Evaluation of retinal vessels in cardiovascular disease traditionally relies upon funduscopy, but more recently digital photo analysis has expanded the spectrum. As spectral domain optical coherence tomography (OCT) allows an in-vivo assessment of retinal tissue and its vessels on a histological scale, our study aimed at using this tool for ...
Xu David D Cleveland Clinic Foundation, 9500 Euclid Ave, NA-21, Cleveland, OH, 44195, United - - 2014
Purpose: To demonstrate a novel automated algorithm for segmentation of intraoperative optical coherence tomography (iOCT) imaging of fluid interface gap in Descemet stripping automated endothelial keratoplasty (DSAEK) and to evaluate the effect of intraoperative maneuvers to promote graft apposition on interface dimensions. Methods: 30 eyes of 29 patients from the ...
Harazny Joanna M JM aDepartment of Nephrology and Hypertension, University of Erlangen-Nuremberg, Erlangen-Nuremberg, Germany bDepartment of Pathophysiology cDepartment of Nephrology and Hypertension, University of Warmia and Masury, Olsztyn, Poland dDepartment of Ophthalmology, University of Erlangen-Nuremberg, Erlangen-Nuremberg, - - 2014
Increased pulsatile pressure induces as well as aggravates microvascular damage. Scanning laser Doppler flowmetry allows the noninvasive assessment of both retinal capillary flow (RCF) and arteriolar structural parameters of the retinal circulation. Moreover, pulsatile characteristics of the retinal arterioles can be assessed. In study 1, reliability of pulsatile RCF and ...
Hsu Chih-Chien CC Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan, - - 2014
In the population-based Shihpai Eye Study, patients aged >65 years with myopic maculopathy were found to have higher systolic blood pressure. This finding deserved further exploration because this is the only correctable factor for preventing maculopathy in patients with high myopia. Therefore, we investigated the association between myopic maculopathy and ...
Müller Alexander A Department of Chemistry, University of Cologne, Luxemburger Straße 116, 50939 Cologne, - - 2014
CO2-microemulsions show strong pressure dependent properties. Using time-resolved SANS to investigate the kinetics of structural changes upon periodic pressure jumps of adjustable amplitude, we found that the compression-induced formation of cylinders occurs on a timescale of one second, whereas the expansion-induced disintegration into CO2 swollen spherical micelles is much faster.
Kiełczyński Piotr P Institute of Fundamental Technological Research, Polish Academy of Sciences, ul. Pawińskiego 5B, 02-106 Warsaw, Poland. Electronic address: - - 2014
The purpose of the paper is to address, using ultrasonic methods, the impact of temperature and pressure on the physicochemical properties of liquids on the example of diacylglycerol (DAG) oil. The paper presents measurements of sound velocity, density and volume of DAG oil sample in the pressure range from atmospheric ...
He Lin L University of Houston College of Optometry, Houston, TX - - 2014
This study was undertaken to understand the role of anterior chamber pressure (ACP) during pharmacological and Edinger-Westphal (EW) stimulated accommodation in anesthetized monkeys. Experiments were performed on one iridectomized eye each of 7 anesthetized adolescent rhesus monkeys. Accommodation was induced by EW stimulation (n=2) and intravenous administration of 0.25-4.0 mg/kg ...
Cao Yingchun - - 2014
The response of the commercial HC-1550-02 hollow-core photonic bandgap fiber (HC-PBF) to gas pressure applied internally to the hollow-core was experimentally investigated. The transmission spectrum of the HC-PBF was hardly affected by the pressure, while the accumulated phase of the fundamental optical mode showed a normalized pressure sensitivity of 1.044 ...
Guidoboni Giovanna G Department of Mathematical Sciences, Indiana University - Purdue University at Indianapolis, Indianapolis, IN, United States. - - 2014
Retinal hemodynamics plays a crucial role in the pathophysiology of several ocular diseases. There are clear evidences that the hemodynamics of the central retinal artery (CRA) is strongly affected by the level of intraocular pressure (IOP), which is the pressure inside the eye globe. However, the mechanisms through which this ...
Triantafyllou Areti A 3rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, - - 2014
Although impairment of the micro- and macrocirculation is considered inherent to sustained hypertension, there is a substantial lack of studies investigating whether an association exists between micro- and macrovascular damage, especially in early-stage hypertension. We studied a meticulously selected population, free of diabetes and cardiovascular disease, of 223 individuals: 137 ...
Scott Ronald G RG The Wound Care Center, The Medical Center of Plano , Plano, Texas - - 2014
Objective: To evaluate the effectiveness of a new bedside pressure mapping technology for patient repositioning in a long-term acute care hospital. Approach: Bedside caregivers repositioned patients to the best of their abilities, using pillows and positioning aids without the visual feedback from a continuous bedside pressure mapping (CBPM) system. Once ...
Norton C G CG Experimental Thermodynamics, Ruhr-University Bochum, Bochum 44780, - - 2014
A new optical flow cell with a new optical arrangement adapted for high pressures and temperatures using glass fibres to connect light source, cell, and spectrometer has been developed, as part of a larger project comprising new methods for in situ analysis of bio and hydrogen gas mixtures in high ...
Kim Yong Joon YJ Department of Ophthalmology, Soonchunhyang University College of Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of - - 2014
To comprehend the mechanism of focal chorioretinal damage by analysis of the pressure distribution and dynamic pressure induced by infused air during fluid-air exchange. A precise simulation featuring a model eye and a fluid circuit was designed to analyze fluid-air exchange. The pressure distribution, flow velocity, and dynamic pressure induced ...
Villalba-Pinto Luis L Department of Ophthalmology, Hospital Punta Europa, Algeciras, University and Polytechnic Hospital La Fe, Valencia, - - 2014
Systemic high blood pressure is related to a variety of retinal manifestations. We present an atypical case of hypertensive chorioretinopathy with massive bilateral serous retinal detachment. A 26-year-old male with a genitourinary malformation and secondary grade IV chronic kidney failure as well as high blood pressure complained of acute vision ...
Altinkaynak Hasan H Department of Ophthalmology, Ankara Atatürk Education and Research Hospital , Ankara , Turkey - - 2014
Abstract Purpose: To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in eyes of chronic heart failure (CHF) patients. Methods: Fifty-six patients with CHF and 56 age- and gender-matched healthy individuals were enrolled. The SFCT was measured by EDI-OCT. The ejection fraction of ...
Chen Chunyan C College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China; College of Chemical Engineering, Sichuan University, Chengdu 610065, - - 2014
Two rounds of acetone-butanol-ethanol (ABE) fermentation under slight pressure were carried out in the continuous and closed-circulating fermentation (CCCF) system. Spores of the clostridium were observed and counted, with the maximum number of 2.1×10(8) and 2.3×10(8)ml(-1) separately. The fermentation profiles were comparable with that at atmospheric pressure, showing an average ...
Pekel G G Ophthalmology Department, Pamukkale University, Denizli, - - 2014
Choroid, which is the vascular tissue responsible for blood supply to the outer parts of the retina, might be affected by hemodynamic events. We aimed to reveal choroidal thickness and ocular pulse amplitude changes after cardiopulmonary bypass in which gross hemodynamic alterations occur. Forty-two eyes of 42 patients who underwent ...
Freitas Daniele C DC Institut Néel, Centre National de la Recherche Scientifique (CNRS) & Université Joseph Fourier (UJF), 25 Avenue des Martyrs, BP166, F-38042 Grenoble Cedex 9, - - 2014
We determine the pressure phase diagram of the 1111 compounds CaFeAsF and SrFeAsF, up to 20 GPa and down to 4 K by electrical resistivity measurements and the change of structure up to 40 GPa at room temperature. The antiferromagnetic transition temperature, as determined by the derivative peak, shows a minimum at ~5 GPa ...
Bian Kaifu K School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA. - - 2014
We investigated pressure-dependent changes in the optical properties of PbS nanocrystal quantum dots (NQD) by combining X-ray scattering and optical absorption spectroscopy in a diamond anvil cell. We discovered that the excitonic absorption peak vanishes as the NQD crystal structure reversibly undergoes the pressure-induced phase transition from rock-salt to orthorhombic ...
Emeterio Nateras Oscar San OS Research Imaging Institute, University of Texas Health Science Center , San Antonio, TX , USA - - 2014
Abstract Purpose: To verify that a visual fixation protocol with cued eye blinks achieves sufficient stability for magnetic resonance imaging (MRI) blood-flow measurements and to determine if choroidal blood flow (ChBF) changes with age in humans. Methods: The visual fixation stability achievable during an MRI scan was measured in five ...
Ertl M M Department of Neurology, Bezirksklinikum Regensburg, University of - - 2014
Ocular color-coded duplex sonography (OCCS), when performed within the safety limits of diagnostic ultrasonography, is an easy noninvasive technique with high potential for diagnosis and therapy in diseases with raised intracranial pressure and vascular diseases affecting the eye. Despite the capabilities of modern ultrasound systems and its scientific validation, OCCS ...
Sonnentag Sabine - - 2014
Lack of psychological detachment from work during off-job time contributes to the increase in employee exhaustion over time. This study examines the reverse causal path from exhaustion to lack of psychological detachment, suggesting that this reverse process may operate within a relatively short time frame. Specifically, we examine if exhaustion ...
Islam Muhammad M aClinical Epidemiology Unit, Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan bHealth Services & Systems Research, Duke-NUS Graduate Medical School, Singapore, Singapore cDivision of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA dNational Heart and Lung Institute, Imperial College London, London, UK *N.C. and A.D.H. contributed equally to the writing of the - - 2014
Microcirculatory abnormalities precede the onset of hypertension and may explain its familial nature. We examined the relationship between parental blood pressure (BP) and offspring retinal microvasculature in Pakistani trios [father, mother, and child (aged 9-14 years)]. This is a substudy of a population-based trial of BP reduction. Data were available ...
Lee Byeungleul - - 2014
The authors developed a cantilever-arrayed blood pressure sensor array fabricated by (111) silicon bulk-micromachining for the non-invasive and continuous measurement of blood pressure. The blood pressure sensor measures the blood pressure based on the change in the resistance of the piezoresistor on a 5-microm-thick-arrayed perforated membrane and 20-microm-thick metal pads. ...
Hiscox Rachel J RJ *PhD †FRCP, PhD School of Optometry and Vision Sciences (RJH, CP, RVN, KSEE), Cardiff University, Cardiff, Wales, United Kingdom; and All Wales Adult Cystic Fibrosis Centre (IK), University Hospital, Llandough, Cardiff, Wales, United - - 2014
This article aims to describe a case of asymptomatic branch retinal vein occlusion (BRVO) in a patient with cystic fibrosis (CF) and discuss the possible link between the two. A young adult (aged 35 years) with CF who presented for routine ocular examination was found to have a superior temporal ...
Dupas Bénédicte B Ophthalmology Department, Lariboisière Hospital, University Paris Diderot - Sorbonne Paris Cité, AP-HP, Paris, - - 2014
To study spontaneous variations of central macular thickness (CMT) and its relation to blood pressure (BP) in patients with diabetic macular oedema (DME). 23 diabetic patients presenting with DME with a CMT ≥ 260 μm on optical coherence tomography (OCT-3, Carl Zeiss Meditec, CA) were followed every 2 weeks for 3 months. At ...
Lin Hongjun H College of Geography and Environmental Sciences, Zhejiang Normal University, Jinhua 321004, PR China. Electronic address: - - 2014
A lab-scale membrane bioreactor (MBR) was continuously operated to investigate the membrane fouling. A new membrane fouling mechanism: osmotic pressure mechanism in cake layer filtration process was identified. Osmotic pressure was proposed to stem from the retention of counter-ions in the matrix of biopolymers in cake layer. Through Fourier transform ...
Touboul David D Centre de Reference National pour le Keratocone (CRNK), Centre Hospitalo-Universitaire de Bordeaux, Place Amélie Raba-Léon, Bordeaux, 33000, - - 2014
Purpose: To assess corneal stiffening with Supersonic Shear wave Imaging (SSI) technology in an experimental model of iontophoresis-assisted trans-epithelial corneal collagen cross-linking (I-CXL). Methods: 6 rabbits underwent full central I-CXL in one eye. The contralateral eye served as control. In vivo iontophoresis was used for 10 minutes to perform trans-epithelial ...
Salvetti Massimo M Clinica Medica, Department of Clinical and Experimental Sciences, and Ophthalmology, University of Brescia, Brescia, - - 2014
Wall-to-lumen ratio of retinal arterioles might serve as an in vivo parameter of vascular damage. We analyzed the impact of brachial clinic blood pressure (BP), of central BP, and of 24-hour BP on wall-to-lumen ratio (WLR) of retinal arterioles. In 295 subjects (147 men; age range, 22-72 years; mean age, ...
Jonas Jost B JB Department of Ophthalmology, Heidelberg University, Universitatsmedizin Mannheim, Medical Faculty Mannheim, Mannheim, 68167, - - 2014
Purpose: The venous choroidal blood drains through the superior orbital vein into the intracranial cavernous sinus. The cerebrospinal fluid pressure (CSFP) may thus influence the choroidal venous blood pressure. Since volume and thickness of the choroid depend on its pressure, we tested the hypothesis whether the subfoveal choroidal thickness (SFCT) ...
Tran M K MK Département de la Matière Condensée, University of Geneva, CH-1211 Geneva 4, - - 2014
BiTeI is a giant Rashba spin splitting system, in which a noncentrosymmetric topological phase has recently been suggested to appear under high pressure. We investigated the optical properties of this compound, reflectivity and transmission, under pressures up to 15 GPa. The gap feature in the optical conductivity vanishes above p∼9  GPa and ...
Liu Yijin Y Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025, - - 2014
Colossal negative thermal expansion was recently discovered in BiNiO3 associated with a low density to high density phase transition under high pressure. The varying proportion of co-existing phases plays a key role in the macroscopic behavior of this material. Here, we utilize a recently developed X-ray Absorption Near Edge Spectroscopy ...
Ott Christian - - 2014
Patients with diabetes mellitus are at increased risk for microvascular complications. Early changes in microcirculation are characterized by hyperperfusion (e.g. in the retina and kidney) and increased pulse wave reflection leading to increased aortic pressure. We investigated the effects of the DPP-4-inhibitor saxagliptin on early retinal microvascular changes. In this ...
Gramlich Oliver W OW Department of Ophthalmology, University Medical Center Mainz, Experimental Ophthalmology, University Medical Center, Langenbeckstr.1, Mainz, 55101, - - 2014
Purpose:An important, yet not exclusive aspect of primary open angle glaucoma is elevated intraocular pressure (IOP) profiles within fluctuations and pressure peaks. The study aimed at establishing minimal-invasive methods for recurring IOP elevation in rats to investigate the impact of IOP dynamics and pathomorphological retinal alterations during and after IOP ...
Koch Edouard E aClinical Investigation Center 503, Centre Hospitalier National des Quinze-Vingts, INSERM and Université Pierre et Marie Curie-Paris6 bPreventive Cardiovascular Unit, Institute of Cardiometabolism and Nutrition, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris cUniversité Paris-Sud, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, dInstitut Supérieur d'Electronique de Paris, Paris, - - 2014
The wall-to-lumen ratio (WLR) of retinal arteries is a recognized surrogate of end-organ damage due to aging and/or arterial hypertension. However, parietal morphometry remains difficult to assess in vivo. Recently, it was shown that adaptive optics retinal imaging can resolve parietal structures of retinal arterioles in humans in vivo. Here, ...
Smedskjaer Morten M MM Section of Chemistry, Aalborg University, DK-9000 Aalborg, - - 2014
It is known that the coordination number (CN) of atoms or ions in many materials increases through application of sufficiently high pressure. This also applies to glassy materials. In boron-containing glasses, trigonal BO3 units can be transformed into tetrahedral BO4 under pressure. However, one of the key questions is whether ...
Boyer S A E SA MINES ParisTech, CEMEF UMR CNRS 7635, Sophia Antipolis, - - 2014
An original optical high-pressure cell, named CRISTAPRESS, has been especially designed to investigate phase transitions of complex liquids, i.e., polymers, polymer blends, nano-composites, etc. The design of the cell is based on the optical properties of morphological entities through in situ light depolarizing microscopic observations. Pressure up to 200 MPa ...
Fernández José A JA Centre for Experimental Medicine, The Queen's University of Belfast, Belfast, United - - 2014
Pressure myography studies have played a crucial role in our understanding of vascular physiology and pathophysiology. Such studies depend upon the reliable measurement of changes in the diameter of isolated vessel segments over time. Although several software packages are available to carry out such measurements on small arteries and veins, ...
Sun Jiyu J Key Laboratory of Bionic Engineering (Ministry of Education), Jilin University, Changchun 130025, China. - - 2014
In most beetles, the hind wings are thin and fragile; when at rest, they are held over the back of the beetle. When the hind wing unfolds, it provides the necessary aerodynamic forces for flight. In this paper, we investigate the hydraulic mechanism of the unfolding process of the hind ...
Aihara Makoto M Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, - - 2014
To investigate the effect of hyperbaric pressure on purified retinal ganglion cells (RGCs) and the additive effect of hyperbaric pressure on glutamate-induced RGC death. An RGC primary culture from 8-day-old Wistar rats was prepared and cultured in a hyperbaric chamber. The RGC survival rate under various pressure conditions and with ...
Kida Teruyo T Department of Ophthalmology, Osaka Medical College, Osaka, - - 2014
We report our findings in three cases of unilateral macular edema associated with retinal vein occlusion (RVO) that improved after successful treatment of systemic hypertension alone. All three cases had systemic hypertension but no diabetes mellitus or other ocular diseases associated with macular edema. All patients were treated only with ...
Jonas Jost B JB Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, China; Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Mannheim, - - 2014
To examine characteristics of ocular hypertensive subjects and potential associations with estimated cerebrospinal fluid pressure (estCSFP). The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years. Ocular hypertension was defined as intraocular pressure (IOP) >21 mmHg, normal optic nerve head appearance and normal retinal ...
Contreras-Martin Y Y Servicio de Neurología, Hospital Universitario Ntra. Sra. de Candelaria, Santa Cruz de Tenerife, España. Electronic address: - - 2013
Idiopathic intracranial hypertension is a disorder characterised by increased intracranial pressure without evidence of an expansive intracranial process or cerebrospinal fluid cytochemical alterations. We reviewed the medical records of patients with idiopathic intracranial hypertension admitted to our hospital between 1999 and 2009 and who met the modified Dandy criteria. We ...
Li Neng - - 2013
We have investigated the mechanism of densification of a nearly perfect continuous random network (CRN) model of amorphous SiO2 (a-SiO2) glass with 1296 atoms and periodic boundary conditions. The model has no under- or over-coordinated atoms and small bond length and bond angle distributions. This near-perfect model is systematically densified ...
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