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Stergiou George S GS Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, 152 Mesogion Avenue, Athens, 11527, Greece, - - 2014
In the last two decades, considerable evidence on home blood pressure monitoring has accumulated and current guidelines recommend its wide application in clinical practice. First, several outcome studies have shown that the ability of home blood pressure measurements in predicting preclinical target organ damage and cardiovascular events is superior to ...
Ni Xiaoying X Department of Nephrology, People's Hospital of Yinzhou, College of Medicine, Ningbo University, Ningbo, - - 2014
The purpose of this study was to evaluate the effects of spironolactone on dialysis patients with refractory hypertension and possible adverse effects. This was a 12-week prospective, randomized, double-blind trial of 82 patients randomly assigned to 12-week treatment with 25 mg/d spironolactone or placebo as add-on therapy. Visits were scheduled at ...
Djami-Tchatchou Arnaud T AT Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South - - 2014
An inability to show consistent relationships between gene variants and blood pressure (BP) may be confounded by the use of office BP measurement. Whether the difference between office BP and day BP (office-day) is genetically predetermined is unknown. We therefore aimed to determine the intrafamilial aggregation and heritability of office-day ...
Arrieta Alejandro A From the Department of Health Policy and Management, Florida International University, Miami (A.A.); Indiana University Health Methodist Research Institute (J.R.W.), Indiana University School of Medicine (S.J.J.), and Indiana University Richard M. Fairbanks School of Public Health (J.R.W., S.J.J.), Indianapolis; and Department of Economics, Indiana University-Purdue University Indianapolis (N.Q.). - - 2014
Home blood pressure (BP) monitoring has been shown to be more effective than clinic BP monitoring for diagnosing and treating hypertension. However, reimbursement of home BP monitoring is uncommon in the United States because of a lack of evidence that it is cost beneficial for insurers. We develop a decision-analytic ...
Luzardo Leonella L aHypertension Unit, Pathophysiology Department, School of Medicine, Division of Nephrology bLaboratory of Clinical Pathology, School of Medicine, Hospital de Clínicas Dr Manuel Quintela, Universidad de la República, Montevideo, Uruguay cResearch Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, Studies Coordinating Centre, University of Leuven, Leuven, Belgium dDepartment of Epidemiology, Maastricht University, Maastricht, The - - 2014
In the ongoing GEnotipo, Fenotipo y Ambiente de la HiperTensión Arterial en UruguaY (GEFA-HT-UY) study, we applied standardized epidemiological methods to determine complex phenotypes including blood pressure (BP). In this report, we present the quality control of the conventionally measured BP. Three trained observers measured BP five times consecutively in ...
Hermida Ramón C RC Bioengineering & Chronobiology Laboratories, Atlantic Research Center for Information and Communication Technologies (AtlantTIC), University of Vigo, Vigo, Spain, - - 2014
Diagnosis of resistant hypertension (RH) is currently based upon awake-time office blood pressure (BP). An increasing number of studies have documented abnormally elevated sleep-time BP in most RH patients, indicating that diagnosis of true RH cannot be determined solely by comparison of office BP with either patient awake-time BP self-measurements ...
Breaux-Shropshire Tonya Lynn - - 2014
Blood pressure control remains a serious public health issue because hypertension is the most common risk factor for cardiovascular disease. Effective management of hypertension often requires lifestyle modification and medication adherence. The objective of this study was to identify the prevalence of blood pressure control, medication adherence, self-monitoring of blood ...
Najlah Mohammad M School of Pharmacy, Faculty of Science and Engineering, University of Wolverhampton , Wolverhampton , - - 2014
Abstract In this study, a niosome nanodispersion was manufactured using high-pressure homogenization following the hydration of proniosomes. Using beclometasone dipropionate (BDP) as a model drug, the characteristics of the homogenized niosomes were compared with vesicles prepared via the conventional approach of probe-sonication. Particle size, zeta potential, and the drug entrapment ...
Trimarco Valentina V Hypertension Research Center, Federico II University Hospital, via S. Pansini 5, bld. 2, 80131, Naples, - - 2014
The recommendation to start antihypertensive therapy with diuretics (D) might produce delay in blood pressure (BP) control and, possibly, increase cost/benefit ratio. We evaluate the effects of D in relation to the administration of other anti-hypertensive medications, in clinical practice. General practitioners recruited 2,409 hypertensive patients with indication to antihypertensive ...
Simon J Palfreyman P Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield University, Sheffield, UK. Electronic address: - - 2014
Pressure ulcers have an adverse impact on patients and can also result in additional costs and workload for healthcare providers. Interventions to prevent pressure ulcers are focused on identifying at risk patients and using systems such as mattresses and turning to relieve pressure. Treatments for pressure ulcers are directed towards ...
Bunker Jill J Peart-Rose Clinic, Imperial College Healthcare NHS Trust, - - 2014
Hypertension is a serious and common condition, the prevalence of which is set to rise given the increase in the ageing population, sedentary lifestyles and obesity. This article reviews the management of primary hypertension in adults, with reference to the National Institute for Health and Care Excellence guidelines. Diagnosis using ...
Biswas Olivia S OS California Medical Institute, Beverly Hills, CA, - - 2014
Nitric oxide (NO) is an integral molecule especially important in the regulation of the cardiovascular system. Literature indicates that the number of studies continues to grow with regard to the effects of NO on cardiovascular disease and hypertension. "Prehypertension" is the clinical stage leading to hypertension. Diet and lifestyle modifications ...
Caligiuri Stephanie Pb - - 2014
In 2013 the World Health Organization deemed hypertension as a global crisis as it is the leading risk factor attributed to global mortality. Therefore, there is a great need for effective alternative treatment strategies to combat a condition that affects 40% of adults worldwide. Recently, the FlaxPAD Trial observed a ...
Bernocchi Palmira - - 2014
Control of blood pressure is frequently inadequate in spite of availability of several classes of well tolerated and effective antihypertensive drugs. Several factors, including the use of suboptimal doses of drugs, inadequate or ineffective treatments and poor drug compliance may be the reason for this phenomenon. The aim of the ...
Cagnacci Angelo A Department of Medical and Surgical Sciences of the Mother, Child and Adult, Institute of Obstetrics and Gynaecology, University of Modena and Reggio Emilia, Modena, Italy, - - 2014
The purpose of this study was to evaluate whether folate exerts antioxidant effects in postmenopausal women and whether this effect is related to folate-induced modification of 24-h ambulatory blood pressure (BP). Double-blind placebo-controlled study performed in 30 apparently healthy postmenopausal women recruited at the outpatient service of University Hospital. Women, ...
Viera Anthony J AJ Department of Family Medicine, University of North Carolina School of Medicine, Chapel Hill, North Carolina; Hypertension Research Program, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; - - 2014
Masked hypertension (MH)-nonelevated office blood pressure (BP) with elevated out-of-office BP average-conveys cardiovascular risk similar to or approaching sustained hypertension, making its detection of potential clinical importance. However, it may not be feasible or cost-effective to perform ambulatory BP monitoring (ABPM) on all patients with a nonelevated office BP. There ...
Digiglio Philip P Micro-Nano Innovations (MiNI) Laboratory, Department of Biomedical Engineering, Department of Electrical and Computer Engineering, The University of California, Davis, CA, 95616, - - 2014
Personalized mobile medicine will continue to advance through the development of wearable sensors that can wirelessly provide pertinent health information while remaining unobtrusive, comfortable, low cost, and easy to operate and interpret. It is the intention that the sensor presented hereafter can contribute to such innovation. By applying a combination ...
Davis Marguerite L ML University of Massachusetts Medical School, Worcester, MA, - - 2014
Elevated blood pressure (BP) is rising in children. Significant proportions of children have reactive hypertension or masked hypertension, making ambulatory BP monitoring (ABPM) a valuable tool, although with potential economic implications. In youth referred for elevated BP, we sought clinic BP combinations that obviated the need for ABPM and to ...
Hall Eleanor E Thomas University Division of Nursing, Thomasville, GA, USA - - 2014
This study explored Latino migrant/seasonal farmworkers' (MSFWs') adherence to hypertension treatment. A cross-sectional correlational study was conducted. Forty-five Latino MSFWs from two farmworker health clinics completed Spanish versions of the Morisky Medication Adherence Scale, the Blood Pressure Knowledge Scale and Blood Pressure Self-Care Scale, the Perceived Stress Scale, the Acculturation ...
Vinyoles Ernest E aLa Mina Primary Care Center, University of Barcelona bBarcelona Research Support Unit, Catalan Health Institute, Barcelona, - - 2014
It is recommended to wait at least 1 min between blood pressure (BP) readings. However, there is insufficient evidence on the utility of this recommendation using a validated automatic device. The aim was to assess differences in BP according to the waiting time between BP readings. The study was designed as ...
Aquilante Christina C Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado. Electronic address: - - 2014
The purpose of this study was to prospectively evaluate the relationship between office, home, and ambulatory blood pressure (BP) in heart transplant recipients. The study enrolled N=30 adults ≥ 6 months following heart transplantation. Morning seated office BP was measured using an automatic device at three outpatient visits. Seated home ...
Niiranen Teemu J TJ From the Population Studies Unit, National Institute for Health and Welfare, Turku, Finland (T.J.N., J.M., P.P., H.K., A.M.J.); and Department of Medicine, Turku University Hospital, Turku, Finland (T.J.N.). - - 2014
Ambulatory blood pressure (BP) is considered as the gold standard of BP measurement although it has not been shown to be more strongly associated with cardiovascular risk than is home BP. Our objective was to compare the prognostic value of office, home, and ambulatory BP for cardiovascular risk in 502 ...
Preston Richard A RA From the Clinical Pharmacology Research Unit, Division of Clinical Pharmacology, Department of Medicine, Miller School of Medicine, University of Miami, FL (R.A.P., D.A., B.J.M., R.R., A.B.A.); Jackson Memorial Hospital, Miami, FL (R.A.P.); Department of Cellular Biology and Pharmacology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL (R.A.P.); Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN (D.A.); and Department of Analytics, Affinnova, Waltham, MA (D.A.). - - 2014
Several consistent lines of evidence indicate an association between sodium sensitivity and impaired nitric oxide bioactivity. Nevertheless, whether restoring nitric oxide in humans by pharmacological means can ameliorate sodium sensitivity has not been investigated. Because nebivolol has been demonstrated to increase nitric oxide bioactivity in both laboratory and clinical investigations, ...
Bakris George L GL The University of Chicago Medicine, Chicago, IL. Electronic address: - - 2014
Prior studies of catheter-based renal artery denervation have not systematically performed ambulatory blood pressure monitoring (ABPM) to assess the efficacy of the procedure. SYMPLICITY HTN-3 was a prospective, blinded, randomized, sham-controlled trial. The current analysis details the effect of renal denervation or a sham procedure on ABPM measurements 6 months ...
Viera Anthony J AJ Departments of aFamily Medicine bMedicine- Division of Cardiology cPsychiatry, University of North Carolina School of Medicine dHypertension Research Program, University of North Carolina at Chapel Hill eDepartment of Biostatistics, University of North Carolina Gillings School of Global Public Health, Chapel Hill, North Carolina, - - 2014
Masked hypertension (MH) refers to nonelevated office blood pressure (BP) with elevated out-of-office BP, but its reproducibility has not been conclusively established. We examined 1-week reproducibility of MH by home BP monitoring (HBPM) and ambulatory BP monitoring (ABPM). We recruited 420 adults not on BP-lowering medication, with recent clinic BP ...
Kwon Eilhann E EE Department of Environment and Energy, Sejong University, Seoul, South - - 2014
Transformation of coconut oil into biodiesel by using dimethyl carbonate (DMC) via a non-catalytic transesterification reaction under ambient pressure was investigated in this study. The non-catalytic transformation to biodiesel was achieved by means of a heterogeneous reaction between liquid triglycerides and gas phase DMC. The reaction was enhanced in the ...
Sesták Jozef J Institute of Analytical Chemistry of the ASCR, v. v. i., Veveří 97, 602 00 Brno, Czech Republic; Faculty of Chemistry, Brno University of Technology, Purkyňova 464/118, 612 00 Brno, Czech - - 2014
Performing gradient liquid chromatography at constant pressure instead of constant flow rate has serious potential for shortening the analysis time and increasing the productivity of HPLC instruments that use gradient methods. However, in the constant pressure mode the decreasing column permeability during a long period of time negatively affects the ...
Sheth Poonam P College of Pharmacy, The University of Arizona, Tucson, Arizona. Electronic address: - - 2014
The selection of accessory devices for pressurized metered-dose inhalers (pMDIs) by health care professionals is typically cost driven without consideration of how the device modifies clinical outcomes. To evaluate nonconventional accessory devices and the open-mouth technique with and without ideal coordination of actuation and inhalation to identify and understand the ...
Männistö Tuija T Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, - - 2014
Chronic air pollution exposure increases risk for hypertensive disorders of pregnancy, but the effect of acute air pollution exposure on blood pressure during pregnancy is less well known. We studied 151,276 singleton term deliveries from the Consortium on Safe Labor (2002-2008) with clinical blood pressure measured at admission to labor/delivery ...
Lavieri Nicolas A NA Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, - - 2014
Sodium nitrite exerts an inhibitory effect on the growth of Listeria monocytogenes. The objective of this study was to investigate the effects of various nitrite concentrations from a vegetable source with and without high hydrostatic pressure (HHP) on the recovery and growth of L. monocytogenes on ready-to-eat restructured ham. A ...
Kerfoot B Price BP From the Veterans Affairs Boston Healthcare System, Boston, MA (B.P.K., D.G., P.R.C.); Harvard Medical School, Boston, MA (B.P.K., A.T., P.R.C.); Brigham and Women's Hospital, Boston, MA (A.T., E.B., P.R.C.); Partners HealthCare, Boston, MA (A.T.); Pharmacoepidemiology Research Group Massachusetts Veterans Epidemiology Research and Information Center, Boston (D.G.); and Boston University School of Public Health, MA (D.G.). - - 2014
Many patients with high blood pressure (BP) do not have antihypertensive medications appropriately intensified at clinician visits. We investigated whether an online spaced-education (SE) game among primary care clinicians can decrease time to BP target among their hypertensive patients. A 2-arm randomized trial was conducted over 52 weeks among primary ...
Athanasakis Kostas K Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, - - 2014
Hypertension represents one of the major contributors to the disease burden and to healthcare expenditure internationally. The objective of this paper was to conduct a short term cost-effectiveness analysis of hypertension treatment vs. a hypothetical "no-treatment" strategy in Greece. Health-resource use data and clinical outcomes for a cohort of 1453 ...
Baynouna Latifa M LM Ambulatory Health Care Services, SEHA, Al Ain, Abu Dhabi, P.O. Box 1663, United Arab - - 2014
This study aims to study determinants for the control of diabetes and hypertension in Al Ain Ambulatory Healthcare patients. This is a cross sectional observational study of patients attending ambulatory healthcare centers in Al Ain, United Arab Emirates in 2009. From a yearly audit evaluating the care of patients with ...
Mas-Heredia Minerva M Centro de Salud Les Corts, Consorci d'Atenció Primària de Salut Eixample (CAPSE), Barcelona, - - 2014
Blood pressure measurement methods and conditions are determinants of hypertension diagnosis. A recent British guideline recommends systematic 24-h ambulatory blood pressure monitoring. However, these devices are not available at all health centers and they can only be used by 1 patient per day. The aim of this study was to ...
Schwerg Marius M Department of Cardiology and Angiology, Campus Mitte Charité - Universitätsmedizin, Berlin, - - 2014
Although guidelines recommend ambulatory blood pressure (BP) monitoring (ABPM), few data are available regarding the effects of renal denervation (RDN) on 24-hour ABPM values. A total of 44 patients with mean systolic BP ≥135 mm Hg on ABPM despite adequate therapy were included. Basal systolic BP (SBP) and diastolic BP (DBP) ...
Hosseininasab Masumeh M Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, - - 2014
Self-monitoring is reported to have limited efficacy for hypertension management in high-income countries. In this study, we aimed to evaluate the effect of self-monitoring on blood pressure (BP) control in an Iranian population. A randomized controlled trial was conducted on 196 mild to moderate hypertensive patients in an outpatient cardiovascular ...
Kario Kazuomi K Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, School of Medicine, Tochigi, - - 2014
The authors examined the effects of olmesartan-based treatment on clinic systolic blood pressure (CSBP) and morning home systolic blood pressure (HSBP) in 21,340 patients with masked hypertension (MH), white-coat hypertension (WCH), poorly controlled hypertension (PCH), and well-controlled hypertension (CH) using data from the Home Blood Pressure Measurement With Olmesartan Naive ...
Daga Subhashchandra S Department of Pediatrics, Maharashtra Institute of Medical Education and Research (MIMER) Medical College, Talegaon Dabhade, Pune 410507, - - 2014
Objective: To study the effectiveness of locally assembled low-cost version for continuous positive airway pressure (CPAP) delivery.Patients: Babies with respiratory distress from two contiguous periods, one with CPAP therapy and the other without, were compared for following parameters: birth weight, gestational age, severity of respiratory distress, as assessed by Silverman-Anderson ...
Sponton Carlos G CG - - 2014
The number of studies that have evaluated exercise training and NOS3 gene polymorphisms is scarce. The present study was designed to evaluate the relationship between exercise training (ET) and NOS3 polymorphisms at -786T>C, 894G>T and Intron 4 b/a on blood pressure, using 24 h ambulatory blood pressure monitoring (ABPM), nitrate/nitrite ...
Zheng Ya-Li - - 2014
24-hour blood pressure (BP) has significant prognostic value for cardiovascular risk screening, but the present BP devices are mainly cuff-based, which are unsuitable for long-term BP measurement, especially during nighttime. In this paper, we developed an armband wearable pulse transit time (PTT) system for 24-hour cuff-less BP measurement and evaluated ...
Persu Alexandre A 1] Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université Catholique de Louvain, Brussels, Belgium [2] Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, - - 2014
Resistant hypertension as defined by the European Society of Hypertension and American Heart Association is a blood pressure that remains uncontrolled despite concomitant intake of at least three antihypertensive drugs (one of them preferably being a diuretic) at full doses. This definition is still based on office rather than out-of-office ...
Jin Yu Y Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, Department of Cardiovascular Sciences, University of Leuven , Leuven , - - 2014
The SYMPLICITY studies showed that renal denervation (RDN) is feasible as novel treatment for resistant hypertension. However, RDN is a costly and invasive procedure, the long-term efficacy and safety of which has not yet been proven. Therefore, we designed the INSPiRED trial to compare the blood pressure lowering efficacy and ...
O'Neill Jessica L JL Department of Ambulatory Care, Veterans Affairs (VA) Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI, 48105, USA, - - 2014
Clinical Pharmacy Specialists (CPSs) and Registered Nurses (RNs) are integrally involved in the Patient Aligned Care Teams (PACT) model, especially as physician extenders in the management of chronic disease states. CPSs may be an alternative to physicians as a supporting prescriber for RN case management (RNCM) of poorly controlled hypertension. ...
Norcliffe-Kaufmann Lucy L Department of Neurology, Dysautonomia Research Center, New York University, New York, NY, 10016, USA, - - 2014
Management of blood pressure (BP) abnormalities in patients with autonomic failure is usually based on office BP readings. It is uncertain, whether office readings reflect actual BPs during a typical day. Therefore, in 45 patients with autonomic failure, we compared office BP values during a tilt test with those captured ...
Rakugi Hiromi H aDepartment of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine bDrug Development Division, Pharmaceutical Development Division, Takeda Pharmaceutical Company Limited, Osaka cDepartment of Medicine, Division of Cardiovascular Medicine, Jichi Medical University School of Medicine, Tochigi-ken, - - 2014
Morning blood pressure (BP) surge is reported as a risk factor for cardiovascular events and end-organ damage independent of the 24-h BP level. Controlling morning BP surge is therefore important to help prevent onset of cardiovascular disease. We compared the efficacy of azilsartan and candesartan in controlling morning systolic BP ...
Gillespie Brigid M BM NHMRC Centre of Research Excellence in Nursing, Griffith University, Brisbane, Queensland, - - 2014
A pressure ulcer (PU), also referred to as a 'pressure injury', 'pressure sore', or 'bedsore' is defined as an area of localised tissue damage that is caused by unrelieved pressure, friction or shearing forces on any part of the body. PUs commonly occur in patients who are elderly and less ...
Lambert Thomas T Cardiovascular Division, Linz General Hospital, Linz, - - 2014
The sympathetic nervous system is an important factor in hypertension. In patients suffering from resistant hypertension, transfemoral renal sympathetic denervation (RDN) reduces office blood pressure (BP) values. Ambulatory BP measurement (ABPM) is a better predictor than office BP of cardiovascular morbidity and mortality. We thus believe that ABPM should be ...
Angeli Fabio F Division of Cardiology and Cardiovascular Pathophysiology, University Hospital "S.M. della Misericordia", Perugia, - - 2014
Accurate blood pressure (BP) measurement is essential for the diagnosis, monitoring and management of hypertension. However, conventional office-based BP readings have several limitations that include a low reproducibility, the white-coat effect and the existence of masked hypertension. These limitations can be addressed through the use of ambulatory BP monitoring. Because ...
Santoro Carlo C Department of Civil and Environmental Engineering, University of Connecticut, Storrs, CT 06269, USA; C2E2 - Center for Clean Energy Engineering, University of Connecticut, Storrs, CT 06269, USA; Department of Chemical & Nuclear Engineering, Center for Emerging Energy Technologies, University of New Mexico, Albuquerque, NM 87131, - - 2014
Activated carbon (AC) is employed as a cost-effective catalyst for cathodic oxygen reduction in microbial fuel cells (MFC). The fabrication protocols of AC-based cathodes are conducted at different applied pressures (175-3500psi) and treatment temperatures (25-343°C). The effects of those parameters along with changes in the surface morphology and chemistry on ...
Bernabe-Ortiz Antonio - - 2014
Controlling hypertension rates and maintaining normal blood pressure, particularly in resource-constrained settings, represent ongoing challenges of effective and affordable implementation in health care. One of the strategies being largely advocated to improve high blood pressure calls for salt reduction strategies. This study aims to estimate the impact of a population-level ...
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