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Assadian Ojan - - 2010
The physical capacity of negative pressure wound therapy (NPWT) dressing on the bacterial growth in an in vitro wound model was investigated. Standardised wounds were contaminated with a clinical Staphylococcus aureus strain and incubated at 35 degrees C for 6 hours. Four wounds were treated with continuous negative pressure (125 ...
Scimeca Christy L - - 2010
Negative-pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. The authors present a description of real-time streaming therapy of a variety of wound chemotherapeutic agents through NPWT. Doxycycline, which acts as a competitive inhibitor of matrix metalloproteinases and tumor necrosis factor alpha and further decreases inflammation ...
Takase Maki - - 2010
We present a case of low-pressure injection injury of the left index finger caused by puncture of the nozzle of a spray can. It resulted in symptoms as severe as those from a high-pressure injection injury. Several debridements meant that the finger did not have to be amputated. The raw ...
Borgquist Ola - - 2010
Negative pressure wound therapy (NPWT) results in 2 types of tissue deformation, macrodeformation (ie, wound contraction) and microdeformation (ie, the interaction of tissue and dressing on a microscopic level). These effects have been delineated for one type of wound filler, foam, but not for gauze. The mechanical deformation initiates a ...
Collinge Cory - - 2010
OBJECTIVES: To compare three commonly used methods and devices developed for measurement of intracompartmental pressure in injured limbs. SETTING: Level II regional trauma center. PATIENTS/PARTICIPANTS: Consecutive patients treated for extremity trauma suspected to have compartment syndrome. INTERVENTION: Analysis of compartment pressure data collected using 1) a solid-state transducer intracompartmental catheter; ...
Oshino Satoru - - 2010
BACKGROUND: To examine the strength and tolerance of the fibrin glue sealant in a situation of extended transsphenoidal surgery. The withstand pressure of fibrin glue sealant was measured using a simple sellar reconstruction model. METHODS: A 15-mm diameter hole at the bottom of a 51-cm high cylinder was covered with ...
Ousey Karen - - 2010
Effective communication to ensure maintenance of a seamless quality service for patients being transferred to the community from the acute sector with negative pressure wound therapy (NPWT) is essential. This paper reports the findings of a focus group convened to explore the decision making process; controversy or conflict surrounding the ...
Wyffels Jennifer T - - 2010
The incidence rate of pressure ulcers in the USA ranges from 0.4% to 38% in acute care settings and from 2.2% to 23.9% in long-term care settings, and their treatment costs are in the billions of dollars yearly. The proteome of wound fluid may contain early indicators or biomarkers associated ...
Hsu Chih-Chin - - 2010
Negative-pressure wound therapy has recently gained popularity in chronic wound care. This study attempted to explore effects of different negative pressures on epithelial migration in the wound-healing process. The electric cell-substrate impedance sensing (ECIS) technique was used to create a 5 x 10(-4) cm(2) wound in the Madin-Darby canine kidney ...
Durai R - - 2010
Active drains, which work by negative pressure, require a closed space for retaining the vacuum. Here the authors describe their novel technique of combining a J-Vac drain and the sponge of a vacuum assisted closure dressing pack to drain a rectal wound. This modification may be useful for rectal wounds ...
Fong Kenton D KD Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford University, Stanford, CA, - - 2010
Negative-pressure wound therapy is traditionally achieved by attaching an electrically powered pump to a sealed wound bed and applying subatmospheric pressure by means of gauze or foam. The Smart Negative Pressure (SNaP) System (Spiracur, Inc., Sunnyvale, Calif.) is a novel ultraportable negative-pressure wound therapy system that does not require an ...
Nakayama Mitsuyuki - - 2010
Negative pressure therapy was applied to 39 deep pressure ulcers covered by soft necrotic tissue. All of the wounds were so deep that there were bones or ligaments just beneath the soft necrotic tissue. They had already received several types of conservative therapy including a necrotomy for periods ranging from ...
Negosanti Luca - - 2010
We report the case of a newborn with acute myeloid leukaemia, who developed perineal necrotizing fasciitis due to Pseudomonas Aeruginosa, after twenty days of life. Following surgical debridement, she was effectively treated with topical negative pressure therapy (V.A.C.(R) device) with silver foam dressings, this achieved complete closure in thirteen days. ...
Gegel Brian T - - 2010
The purpose of this study was to compare the effectiveness of 2 hemostatic agents, chitosan-based Celox and the biopolymeric, microporous particles TraumaDEX, with a control group in a porcine model of hemorrhage. The animals were randomly assigned to 1 of 3 groups: Celox (n = 5), TraumaDEX (n = 5), ...
Shuler Michael S - - 2010
BACKGROUND: Near-infrared spectroscopy estimates soft-tissue oxygenation approximately 2 to 3 cm below the skin. The purpose of the present study was to evaluate muscle oxygenation in the setting of an acute compartment syndrome of the leg and to determine if near-infrared spectroscopy is capable of detecting perfusion deficits. METHODS: Fourteen ...
Borgquist Ola - - 2010
Negative pressure wound therapy (NPWT) alters wound edge microvascular blood flow. Some preclinical data suggest that cycling between low and high negative pressure may be more beneficial than continuous NPWT. The purpose of this in vivo study was to compare the effect of intermittent negative pressure (cycled either from 0 ...
Lohi J - - 2010
A vast range of dressings can be used on pressure ulcers, but despite this and the high expense often involved, there is no gold standard for the local treatment of these wounds. This literature review therefore set out to examine the evidence.
Tschan Christoph A - - 2010
OBJECT: Waterjet dissection has been shown to separate tissues of different resistance, with preservation of blood vessels. In cranioplasty, separation of subcutaneous tissue and dura mater is often difficult to achieve because the various tissue layers strongly adhere to each other after decompressive craniotomy. In the present study, the potential ...
Chaiken J - - 2010
We present instrumentation for probing of volar side fingertip capillary beds with free space coupled near infrared light while collecting Raman, Rayleigh, and Mie scattered light as well as fluorescence. Fingertip skin capillary beds are highly vascularized relative to other tissues and present a desirable target for noninvasive probing of ...
Engelke Wilfried - - 2011
Oral posture is considered to have a major influence on the development and reoccurrence of malocclusion. A biofunctional model was tested with the null hypotheses that (1) there are no significant differences between pressures during different oral functions and (2) between pressure measurements in different oral compartments in order to ...
Kolkman I - - 2010
This article describes a study of the behaviour of double muscled Belgian Blue (BB) cows during the peri partum period to assess the differences in pain perception in cows calving per vaginam vs cows delivering by caesarean section (CS). In one herd, a total of 30 multiparous cows, of which ...
Shuler Franklin D - - 2010
BACKGROUND: Serial physical examination is recommended for patients for whom there is a high index of suspicion for compartment syndrome. This examination is more difficult when performed on an obtunded patient and relies on the sensitivity of manual palpation to detect compartment firmness-a direct manifestation of increased intracompartmental pressure. This ...
Durai Rajaraman - - 2010
High- and low-pressure vacuum drains are commonly used after surgical procedures. High-pressure vacuum drains (ie, sealed, closed-circuit systems) are efficient and allow for easy monitoring and safe disposal of the drainage. Low-pressure vacuum drains use gentle pressure to evacuate excess fluid and air, and are easy for patients to manage ...
Hon Janice - - 2010
Monitoring wound progress is essential for evaluating and documenting treatment outcomes. The Pressure Ulcer Scale for Healing (PUSH) was developed to track pressure ulcer (PU) progress but information about its utility for other types of chronic wounds is limited. A 10-month, descriptive, multicenter study was conducted to examine the responsiveness ...
Bitsch Rudi G - - 2011
Cementing irregularities have been associated with femoral failures of resurfacing arthroplasties in retrieval studies. We used an in vitro model to measure pressure, temperatures, and cement penetration as a function of 6 different cementing techniques. Filling the component with cement can lead to overpenetration or increase the resistance to component ...
Milic Dragan J - - 2010
Venous leg ulcers (VLU) have a huge social and economic impact. An estimated 1.5% of European adults will suffer a venous ulcer at some point in their lives. Despite the widespread use of bandaging with high pressure in the treatment of this condition, recurrence rates range between 25% to 70%. ...
Cohenca Nestor - - 2010
OBJECTIVE: The aim of this study was to compare in vivo the efficacy of 2 root canal disinfection techniques (apical negative pressure irrigation versus apical positive pressure irrigation plus triantibiotic intracanal dressing) in immature dog teeth with apical periodontitis. STUDY DESIGN: Two groups of root canals with pulp necrosis and ...
Moghimi Sahar - - 2010
Abstract-This article focuses on the development of a method to quantitatively assess the healing process of artificially induced pressure sores using high-frequency (20 MHz) ultrasound images. We induced sores in guinea pigs and monitored predefined regions on days 3, 7, 14, and 21 after sore generation. We extracted relevant parameters ...
Giovinco Nicholas A - - 2010
INTRODUCTION: Although the use of negative pressure wound therapy (NPWT) is broadly efficacious, it may foster some potentially adverse complications. This is particularly true in patients with diabetes who have a wound colonized with aerobic organisms. Traditional antiseptics have been proven useful to combat such bacteria but require removal of ...
Meggs William Joel - - 2010
STUDY OBJECTIVE: Pressure-immobilization bandages sequester venom in extremities and are recommended for snakebites without local toxicity. Pilot studies were performed to determine the time of onset of toxicity and efficacy of pressure-immobilizations bandages in a porcine model of rattlesnake envenomation. METHODS: After IACUC approval, anesthetized pigs were injected subcutaneously in ...
Smith B N - - 2010
The Rim Cutter (Stryker Orthopedics, Mahwah, New Jersey) is a tool designed to cut a ledge inside the rim of the acetabulum, onto which a precisely trimmed, cemented, flanged cup can be fitted. The aim was to investigate the effect of the Rim Cutter on the intra-acetabular cement mantle pressure ...
Ganeshanantham G - - 2010
Abdominal compartment syndrome is a lethal yet under appreciated complication of vascular surgery. The World Society of Abdominal Compartment Syndrome conference in 2004 culminated recent research to formulate the internationally accepted definitions and promote education, in an attempt to reduce a quoted 82% mortality. The syndrome has a broad aetiology, ...
Weston C - - 2010
Topical negative pressure therapy (TNP) is an established part of modern wound healing. With an increasing choice in TNP providers, understanding the differing modes of action, the biochemical and biophysical effects on the wound at a microscopic and macroscopic level, plus the role of the interface dressings, will aid the ...
Wetton Lara - - 2010
BACKGROUND: Successful skin grafting requires multiple factors for success. An even distribution of constant pressure exerted upon the graft is necessary for successful graft take. It is well known that excessive pressure on a graft causes ischemia and may result in the failure of graft take. The aim of this ...
- - 2010
Open fractures frequently result in serious complications for patients, including infections, wound healing problems, and failure of fracture healing, many of which necessitate subsequent operations. One of the most important steps in the initial management of open fractures is a thorough wound irrigation and debridement to remove any contaminants. There ...
Aziz Zoriah - - 2010
Pressure ulcers are defined as areas "of localized damage to the skin and underlying tissue caused by pressure, shear, friction and/or the combination of these". Electromagnetic therapy (EMT), in which electrodes produce an electromagnetic field across the wound, may improve healing of chronic wounds such as pressure ulcers. To assess ...
Torbrand Christian - - 2010
Negative pressure wound therapy (NPWT) is believed to initiate granulation tissue formation via macro-deformation of the wound edge. However, only few studies have been performed to evaluate this hypothesis. The present study was performed to investigate the effects of NPWT on wound contraction and wound edge tissue deformation. Six pigs ...
Chesnick Ingrid E IE 1. Department of Biophysics, Armed Forces Institute of Pathology, Rockville, Maryland, - - 2010
Formaldehyde fixation and paraffin-embedding remains the most widely used technique for processing cancer tissue specimens for pathologic examination, the study of tissue morphology, and archival preservation. However, formaldehyde penetration and fixation is a slow process, requiring a minimum of 15 hr for routine processing of pathology samples. Routinely fixed samples ...
Noordin Shahryar - - 2009
Higher levels of tourniquet pressure and higher pressure gradients beneath tourniquet cuffs are associated with a higher risk of nerve-related injury. Measurement of limb occlusion pressure can help to minimize tourniquet pressure levels and pressure gradients for individual patients and individual surgical procedures. Selective use of pneumatic, wider, and contoured ...
Psoinos Charles M - - 2009
Negative pressure wound therapy (NPWT) is described as it is used in the treatment of an infant burn victim. This case highlights the ability and techniques used to maintain an airtight dressing seal in the perirectal region. Use of this dressing type post-skin grafting allowed for 100% graft adhesion and ...
Kopec Michael - - 2009
BACKGROUND: Gun pressurization in total knee arthroplasty (TKA) may result in better cement penetration than hand packing, leading to fewer tibial plate failures. We compared cement intrusion characteristics between vacuum mixing and gun pressurization versus hand mixing and packing in the proximal tibia among patients undergoing TKA. METHODS: We analyzed ...
Durai R - - 2009
Active drains, which work from negative pressure effect, are commonly used to drain closed airtight wounds. Higher negative pressure is used in vacuum assisted wound closure (VAC) (usually -125 mmHg) dressings and in Redivac system (usually -300 mmHg). As far as we know, combinations of Redivac and VAC have not ...
Voermans R P - - 2009
BACKGROUND AND STUDY AIMS: Secure transluminal closure remains a fundamental barrier to clinical introduction of natural orifice transluminal endoscopic surgery (NOTES). Current NOTES closure modalities either do not provide secure closure or are too challenging to apply in vivo. The aims of this study were to evaluate gastric closure using ...
Marquardt C - - 2009
Today, the biomechanical fundamentals of skin expansion are based on viscoelastic models of the skin. Although many studies have been conducted in vitro, analyses performed in vivo are rare. Here, we present in vivo measurements of the expansion at the skin surface as well as measurement of the corresponding intracutaneous ...
Ellinger Sabine - - 2009
PURPOSE OF REVIEW: This review evaluates the efficacy of vitamin supplementations for prevention and treatment of pressure ulcer and surgical wounds on the basis of recent clinical intervention studies. RECENT FINDINGS: Intervention studies show that an energy and protein-rich oral nutritional supplement providing high doses of vitamin C and zinc ...
Chakraborty P D - - 2009
The healing properties of placental extract are well established in various skin conditions, including chronic wounds, pressure ulcers and burns. However, its biochemical composition and mechanisms of action are still largely unknown.
Wong S Lindsey - - 2009
Brown recluse spider (Loxosceles sp) bites continue to be a significant challenge to manage clinically. Sequelae from these lesions range from chronic necrotic ulcers that persist for months to an acute life-threatening course of sepsis. Negative pressure wound therapy using vacuum-assisted closure (VAC) has been described for use in both ...
J??nger M - - 2009
OBJECTIVE: To compare changes in interface pressures of three compression systems (four layer, two layer and short stretch) recorded over seven days in healthy volunteers in different positions: supine, sitting, active standing and working pressure during exercise. METHOD: Twenty-four volunteers were bandaged with one of the three compression systems on ...
Makhsous Mohsen M Departments of Physical Therapy and Human Movement Sciences, Physical Medicine and Rehabilitation, Orthopaedic Surgery, Northwestern University, Chicago, Illinois, - - 2009
To evaluate whether an individualized cyclic pressure-relief protocol accelerates wound healing in wheelchair users with established pressure ulcers (PrUs). Randomized controlled study. Spinal cord injury clinics. Forty-four subjects, aged 18-79 years, with a Stage II or Stage III PrU, were randomly assigned to the control (n = 22) or treatment ...
Kim Tae Hyung - - 2009
Unfavorable relationships between the residual edentulous ridge, pontic, and gingival papilla may compromise the definitive result of a restoration. Different procedures have been described and developed to improve the relationship between esthetics and functionally acceptable fixed partial dentures. This article describes a unique pontic design as well as the application ...
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