Search Results
Results 351 - 400 of 1678
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Guazzi Marco - - 2013
Echo-derived pulmonary artery systolic pressure (PASP) and right ventricular (RV) tricuspid systolic excursion (TAPSE) are of relevance in the clinical follow-up of heart failure (HF), carrying 2 to 3 fold increase in cardiac risk when altered. We hypothesized that the relationship between TAPSE (longitudinal RV fiber shortening) and PASP (force ...
Hensel Kendi L - - 2013
The physiological changes that occur during pregnancy, including increased blood volume and cardiac output, can affect hemodynamic control, most profoundly with positional changes that affect venous return to the heart. By using Osteopathic Manipulative Treatment (OMT), a body-based modality theorized to affect somatic structures related to nervous and circulatory systems, ...
Hummel Scott L SL Department of Internal - - 2013
Heart failure with preserved ejection fraction (HFPEF) involves failure of cardiovascular reserve in multiple domains. In HFPEF animal models, dietary sodium restriction improves ventricular and vascular stiffness and function. We hypothesized that the sodium-restricted dietary approaches to stop hypertension diet (DASH/SRD) would improve left ventricular diastolic function, arterial elastance, and ...
Howorka Kinga - - 2013
Our aim was to investigate medium-term effects of device-guided breathing on blood pressure (BP) and its capacity to improve the cardiovascular autonomic balance in hypertensive diabetic patients. This feasibility study was conceived as a proof-of-concept trial under real life conditions for justification of further investigations. A randomized, controlled study (RCT) ...
Davenport Andrew - - 2013
To evaluate the non-invasive assessments of volume status in patients with cirrhosis. Echocardiography and multifrequency bioimpedance analysis measurements and short synacthen tests were made in 20 stable and 25 acutely decompensated patients with cirrhosis. Both groups had similar clinical assessments, cortisol response and total body water (TBW), however the ratio ...
Christofidis Melany J - - 2013
To investigate whether overlapping blood pressure and heart rate graphs improve chart-users' ability to recognize derangements in these vital signs on hospital observation charts. Many health professionals prefer blood pressure and heart rate graphs to overlap. One justification is the use of a visual cue called the 'Seagull Sign' to ...
Quinaglia Thiago - - 2013
Failure to control blood pressure (BP) despite the use of three or more drugs characterizes resistant hypertension (RHTN). Impaired endothelial function is associated with this condition and phosphodiesterase-5 inhibitors (PDE5i)-inhibiting cGMP breakdown-reduce BP in RHTN patients. We hypothesized that acute administration of PDE5i could ameliorate hemodynamic, endothelial parameters and left ...
Niemirska Anna - - 2013
Primary hypertension is associated with disturbed activity of the sympathetic nervous system and altered blood pressure rhythmicity. We analyzed changes in cardiovascular rhythmicity and its relation with target organ damage during 12 months of antihypertensive treatment in 50 boys with hypertension (median, 15.0 years). The following parameters were obtained before ...
Linz Dominik - - 2013
Obstructive sleep apnea is characterized by repetitive collapses of the upper airway, negative thoracic pressure periods, and intermittent hypoxia, stimulating the autonomic nervous system. The increased sympathetic drive during obstructive sleep apnea results in postapneic blood pressure rises and neurohumoral activation potentially involved in the initiation and progression to permanent ...
Diaper Alison - - 2013
It is generally thought that venlafaxine raises blood pressure at higher doses; however, some studies have found no effect or a decrease in blood pressure. The aim of this study was to evaluate the cardiovascular (CV) effects of 3 weeks of dosing with venlafaxine, pregabalin and placebo on young healthy adults. ...
Grieshammer Steffen - - 2013
We calculate entropies of formation for fully charged point defects, including the small polaron , in undoped fluorite-structured ceria by means of density functional theory in the GGA + U approximation. We discuss the behaviour of the entropy for the constant volume and the constant pressure case. Our results for ...
Baumert Mathias - - 2013
The dynamics of cardiovascular variables are modulated by respiration. The aim of this study was to assess baroreflex function in normal subjects based on the joint symbolic dynamics of heart rate, blood pressure and respiration. ECG, continuous blood pressure and respiration were recorded in ten healthy subjects during rest in ...
Korkmaz Sevil - - 2013
Both advanced donor age and prolonged ischemic time are significant risk factors for the 1-year mortality. However, its functional consequences have not been fully evaluated in the early-phase after transplantation; even early graft dysfunction is the main determinant of long-term outcome following transplantation. We evaluated in vivo left-ventricular (LV) cardiac ...
Pinto Thiago Lorentz - - 2013
The increase in the number of studies has led to greater security in the application of this method and the determination of its effectiveness in adults.. The purpose of the present study was to evaluate heart rate variability in healthy individuals submitted to different levels of positive expiratory pressure using ...
Midoh Naoki - - 2013
The repeated once-daily oral administration of a hot-water extract of porcini, Boletus aestivalis, mushrooms (WEP) to spontaneously hypertensive rats (SHR) for 18 weeks decreased the systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate. The WEP administration also decreased blood urea nitrogen (BUN), creatinine (Cre), and triglyceride (TG), ...
Janssen Wiebke - - 2013
Pulmonary arterial hypertension (PAH) is a progressive disease that is associated with a poor prognosis and results in right heart dysfunction. While pulmonary vascular disease is the obvious primary pathological focus, right ventricular hypertrophy (RVH) and right ventricular (RV) dysfunction are major determinants of prognosis in PAH. Our knowledge about ...
Zhang Siyuan - - 2013
The acoustic pressure distribution, thermal ablation, and sonochemiluminescence (SCL) generated by cavitation near the surface of an ex vivo bovine femur were investigated at normal and oblique incidences of high intensity focused ultrasound (HIFU), as were the characteristics of bone surface vibrations. The acoustic pressure at the HIFU focus, the ...
Pejović Janko - - 2013
Identification of patients with arterial hypertension and a possible onset of heart failure by determining the concentration of N-terminal pro-B-type natriuretic peptide (NT-proBNP) enables timely intensification of treatment and allows clinicians to prescribe and implement optimal and appropriate care. The aim of this study was to evaluate NT-proBNP in patients ...
De Meester Pieter - - 2013
Although closure of an atrial septal defect type secundum often normalizes right heart dimensions and pressures, mild tricuspid insufficiency might persist. This study aimed at (1) identification of determinants explaining the persistence of tricuspid insufficiency after atrial septal defect closure, and (2) evaluation of functional capacity of patients with persistent ...
Ghosh Erina E Cardiovascular Biophysics Laboratory, Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine St. Louis, Missouri ; Department of Biomedical Engineering, School of Engineering and Applied Science, Washington University in St. Louis St. Louis, - - 2013
The pressure phase plane (PPP), defined by dP(t)/dt versus P(t) coordinates has revealed novel physiologic relationships not readily obtainable from conventional, time domain analysis of left ventricular pressure (LVP). We extend the methodology by introducing the normalized pressure phase plane (nPPP), defined by 0 ≤ P ≤ 1 and -1 ...
Tang Hong H Department of Biomedical Engineering, Dalian University of Technology Dalian, - - 2013
The relationships between the amplitude of the first heart sound (S1) and the rising rate of left ventricular pressure (LVP) concluded in previous studies were not consistent. Some researchers believed the relationship was positively linear; others stated the relationship was only positively correlated. To further investigate this relationship, this study ...
Weiner Rory B - - 2013
Hypertension, a strong determinant of cardiovascular disease risk, has been documented among elite, professional American-style football (ASF) players. The risk of increased blood pressure (BP) and early adulthood hypertension among the substantially larger population of collegiate ASF athletes is not known. We conducted a prospective, longitudinal study to examine BP, ...
Grabowski Katja - - 2013
An abnormal increase in left ventricular (LV) mass, i.e. LV hypertrophy (LVH), represents an important target organ damage in arterial hypertension and has been associated with poor clinical outcome. Genetic factors are contributing to variation in LV mass in addition to blood pressure and other factors such as dietary salt ...
Kutty Shelby - - 2013
The aim of this study was to investigate the left ventricular (LV) myocardial contractility index-Emax using transesophageal real time three-dimensional echocardiography (RT3DE) combined with catheterization. Transesophageal RT3DE (single beat, X7-2 × matrix, iE33, Philips) was used to obtain real time LV volumes in pigs. Volumes were integrated with LV pressures from conductance ...
Pagonas Nikolaos N Department of Nephrology, Charité-Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, - - 2013
The introduction of automated oscillometric blood pressure monitors was the basis for today's widespread use of blood pressure self-measurement. However, in atrial fibrillation, there is a controversial debate on the use of oscillometry because there is a high variability of heart rate and stroke volume. To date, the accuracy of ...
Turak Osman - - 2013
Left ventricular (LV) synchronous contraction is impaired in patients with hypertension (HT). The deleterious effects of HT on cardiovascular system are more evident in patients with nondipper HT than dippers. In this study, we aimed to investigate the effect of nondipping HT on LV systolic synchronicity compared with dippers and ...
Reil Jan-Christian - - 2013
The study aimed to determine whether isolated heart rate reduction with ivabradine reduces afterload of patients with systolic heart failure. The effective arterial elastance (Ea) represents resistive and pulsatile afterload of the heart derived from the pressure volume relation. Heart rate modulates Ea, and, therefore, afterload burden. Among the patients ...
Kikuchi Shohei - - 2013
Background: The pathophysiology of abnormal relaxation pattern in the transmitral flow (TMF) velocity waveform has not been fully elucidated. Methods and Results: A total of 173 patients who underwent comprehensive Doppler echocardiography and diagnostic cardiac catheterization for coronary artery disease were enrolled in the study. Peak early and late diastolic TMF velocities ...
Espinoza Andreas A The Intervention Center, Rikshospitalet, Oslo University Hospital, Oslo, Norway; University of Oslo, Oslo, Norway. Electronic address: - - 2013
Therapeutic hypothermia is used after cardiac arrest. The aim of this study was to investigate the effects of therapeutic hypothermia on left ventricular (LV) function assessed by ultrasonic imaging. In 10 pigs, LV volumes, ejection fractions, and longitudinal strain were measured using two-dimensional echocardiography. Midwall fractional shortening and end-systolic wall ...
Esteves William A M - - 2013
We aimed to explore the relationship between brain natriuretic peptide (BNP) levels and right ventricular (RV) function in patients with mitral stenosis (MS), and to investigate the hemodynamic parameters that predict reduction of BNP levels after percutaneous mitral valvuloplasty (PMV). Few studies have evaluated BNP in the context of MS, ...
Goldring Natalie - - 2013
Abstract The isometric wall squat could be utilised in home-based training aimed at reducing resting blood pressure, but first its suitability must be established. The aim of this study was to determine a method of adjusting wall squat intensity and explore the cardiovascular responses. Twenty-three participants performed one 2 minute ...
Mahdiabadi J J Belarusian State University of Physical Culture, Minsk, - - 2013
Exercise plays an important role to improve cardiovascular performance. The aim of this study was to compare the effect of aerobic continuous and interval training on the left ventricular structure and function. Twenty untrained healthy male students (aged 18-22 years) were randomly divided into two groups: continuous (C; n = ...
Giles Thomas D - - 2013
Nebivolol, a vasodilatory β1 -blocker, may be well suited for the hemodynamics of the younger hypertensive patient. In this 8-week trial, 18- to 54-year-olds with a diastolic blood pressure (DBP) of 95 mm Hg to 109 mm Hg who completed a 4-week placebo-only phase were randomized to receive nebivolol (5 mg/d, titrated to ...
Drynan Eleanor A - - 2013
To determine the agreement between blood pressure obtained with a noninvasive technique and direct technique using the Surgivet V9203 at varying blood pressure levels created using a canine hemorrhage model. Experimental study. University Teaching Hospital. Twenty-nine greyhounds with an average weight of 30 kg. Approval from the Murdoch University Animal ...
Seker Taner - - 2013
Vitamin D regulates the renin-angiotensin system, suppresses proliferation of vascular smooth muscle and improves endothelial cell dependent vasodilatation. These mechanisms may play a role on pathogenesis of arterial and left ventricular stiffness. We aimed to investigate the association between serum 25-hydroxyvitamin D with arterial and left ventricular stiffness in healthy ...
Marwan Norbert - - 2013
The asymmetry of coupling between complex systems can be studied by conditional probabilities of recurrence, which can be estimated by joint recurrence plots. This approach is applied for the first time on experimental data: time series of the human cardiorespiratory system in order to investigate the couplings between heart rate, ...
Beigel Roy - - 2013
In current practice, right atrial pressure (RAP) is an essential component in the hemodynamic assessment of patients and a requisite for the noninvasive estimation of the pulmonary artery pressures. RAP provides an estimation of intravascular volume, which is a critical component for optimal patient care and management. Increased RAP is ...
Millar Philip J - - 2013
Atrial mechanoreceptors, stimulated by increased pressure or volume, elicit in healthy humans a net sympathoinhibitory response. The co-existence of an atrial reflex eliciting muscle sympathoexcitation has been postulated but undetected by conventional multi-unit muscle sympathetic nerve activity (MSNA). We hypothesized that in response to a selective increase in atrial pressure, ...
De Meester Pieter - - 2013
The value of the right heart morphology is not well established for the evaluation of elevated pulmonary artery pressure (PAP). We aimed (1) to assess the relationship between right heart morphology and PAP and (2) to evaluate whether morphology can help to exclude elevated PAP. From 11-2010 until 01-2011, 1640 ...
Munte Claudia Elisabeth - - 2013
Folding under pressure: High-pressure NMR spectroscopy detects three different conformational states of the Aβ-peptide in solution: a compactly folded state 1, a partially folded state 2', and a random-coil like state 2'' (see plot, p=population). At ambient pressure the folded state 1 dominates which probably has a high affinity to ...
Roush George C - - 2013
How chlorthalidone (CTDN) reduces risk for cardiovascular events (CVEs) can be considered in light of its ability to lower blood pressure (BP) and its non-BP related, pleiotropic effects. The mechanism by which CTDN lowers BP is unclear but may include alterations in whole body regulation and vasodilatory actions on vasculature, ...
Figueroa-Valverde L - - 2013
Experimental studies indicate that some steroid derivatives have inotropic activity; nevertheless, there is scarce information about the effects of the dehydroisoandrosterone and its derivatives at cardiovascular level. In addition, to date the cellular site and mechanism of action of dehydroisoandrosterone at cardiovascular level is very confusing. In order, to clarify ...
Andrikou Ioannis - - 2013
Left ventricular hypertrophy (LVH) conveys an increased risk of cardiovascular morbidity and mortality. We aimed to compare the prognostic value of daytime and nighttime blood pressure (BP) on the changes in LVH status in newly diagnosed hypertensive subjects. Three hundred and five hypertensive, nondiabetic subjects (mean age 51.1±10.2 years, 190 ...
de Solis Cristobal Navas - - 2013
Objective-To describe the prognosis and clinical, echocardiographic, and pathological features of hypertensive cardiomyopathy in horses. Design-Retrospective case series. Animals-5 horses with cardiac hypertrophy and systemic hypertension. Procedures-Demographics, history, physical and cardiological examination findings, diagnosis, clinical progression, prognosis, and pathological findings were obtained from medical records. Results-The primary diagnosis was chronic ...
Lange S A - - 2013
Closure of atrial septal defects (ASD) prevents pulmonary hypertension, right heart failure and thromboembolic stroke. The exact timing for ASD closure is controversial. In a prospective study to address the question whether unapparent pulmonary hypertension can be revealed prior to right ventricular (RV) remodelling, patients were investigated before and 6, ...
Wu Sheng-Yuan - - 2013
The present control method used in our helical flow total artificial heart (HFTAH) would only need four parameters. Nowadays, gauge pressure sensors are being used to obtain the pressure needed for control parameters. Nevertheless, there are also many following problems such as calibration, maintenance, offset drift and infection due to ...
Shiga Takuya - - 2013
Hemodynamic effects of atrial contraction with centrifugal pump type total artificial heart is unknown. In this study, we simulated an atrial contraction in a mock model. By the driving condition with higher pressure in the mock atrial model, the load during atrial contraction increased. Based on these findings, we examined ...
Leonardi Robert A RA Medical University of South Carolina, Charleston, SC, - - 2013
Fractional flow reserve (FFR), the hyperemic ratio of distal (Pd) to proximal (Pa) coronary pressure, is used to identify the need for coronary revascularization. Changes in left ventricular end-diastolic pressure (LVEDP) might affect measurements of FFR. LVEDP was recorded simultaneously with Pd and Pa during conventional FFR measurement as well ...
Soergel David G - - 2013
TRV027 is a novel β-arrestin biased peptide ligand of the angiotensin II type 1 receptor (AT1R). The compound antagonizes G protein coupling while simultaneously stimulating β-arrestin-mediated signaling. In preclinical studies, TRV027 reversibly reduced blood pressure while preserving renal function in a dog tachypaced heart failure model and stimulating cardiomyocyte contractility ...
Ziemssen Tjalf - - 2013
Biological rhythms, describing the temporal variation of biological processes, are a characteristic feature of complex systems. The analysis of biological rhythms can provide important insights into the pathophysiology of different diseases, especially, in cardiovascular medicine. In the field of the autonomic nervous system, heart rate variability (HRV) and baroreflex sensitivity ...
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