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Results 301 - 350 of 1706
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Soliman Mona M Dr. Mona Soliman, Associate Professor, Department of Physiology, College of Medicine, King Saud University, P.O. Box. 2925 (29), Riyadh 1146, Saudi - - 2013
Myocardial contractile dysfunction plays a major role in the outcome of trauma patients. Nitric oxide (NO) has been shown to increase following haemorrhagic shock. Peroxynitrite which is produced by the reaction of NO with reactive oxygen species leads to nitrosative stress mediated organ injury and myocardial contractile dysfunction. Aminoguanidine is ...
Yotti Raquel - - 2013
-Noninvasive indices based on Doppler-echocardiography are increasingly used in clinical cardiovascular research to evaluate LV global systolic chamber function. Our objectives were 1) to clinically validate ultrasound-based methods of global systolic chamber function to account for differences between patients in conditions of abnormal load, and 2) to assess their sensitivity ...
Groh Georgeann K - - 2013
Doppler echocardiography (DE) is widely used as a surrogate for right heart catheterization (RHC), the gold standard, to assess and monitor elevated right heart pressure in children. However, its accuracy has not been prospectively validated in children. The objectives of this study were to evaluate the accuracy of DE in ...
Onishi Noriyuki - - 2013
Three-dimensional speckle tracking echocardiography (3D-STE) has a major advantage in the improvement of accuracy in the evaluation of cardiac chamber volume without any geometrical assumption. Thus, the aim of this study was to use 3D-STE to elucidate the features of left atrial (LA) volume and function that are altered by ...
Posina Kanna - - 2013
Left atrial volume (LAV) and emptying fraction (LAEF) are phasic during cardiac cycle. Their relationships to left ventricular end diastolic pressure (LVEDP) have not been fully defined. Forty one patients undergoing clinically indicated left heart catheterization were recruited for same day cardiovascular magnetic resonance (CMR). LAV and LAEF were assessed ...
Sarıkaya Savas - - 2013
Abstract Introduction: A relationship between atrial conduction time and hypertension was shown in previous studies. Increased atrial electromechanical intervals used to predict atrial fibrillation by measured tissue Doppler imaging (TDI). So we aimed to search if there was any association between the non-dipping status and atrial electromechanical intervals in pre-hypertensive ...
Molcan L - - 2013
Cardiovascular parameters, such as blood pressure and heart rate, exhibit both circadian and ultradian rhythms which are important for the adequate functioning of the system. For a better understanding of possible negative effects of chronodisruption on the cardiovascular system we studied circadian and ultradian rhythms of blood pressure and heart ...
Mugabo Pierre - - 2013
Asystasia gangentica (A. gangetica) belongs to the family Acanthaceae. It is used to treat hypertension, rheumatism, asthma, diabetes mellitus, and as an anthelmintic in South Africa, India, Cameroun, Nigeria, and Kenya respectively. It has also been reported to inhibit the angiotensin I converting enzyme (ACE) in-vitro. Therefore, the aim of ...
Valdovinos John - - 2013
While Fontan palliation in the form of the total cavopulmonary connection has improved the management of congenital single ventricle physiology, long-term outcomes for patients with this disease are suboptimal due to the lack of two functional ventricles. Researchers have shown that ventricular assist devices (VADs) can normalize Fontan hemodynamics. To ...
Dunn James S - - 2013
Reduced cardiovagal baroreflex sensitivity and a peak in the incidence of cardiovascular events in the hours immediately after waking from nocturnal sleep suggest that cardiovascular control is impaired in the morning compared with other times of day. Previous research indicates that diurnal variation exists in acute blood pressure (BP) responses ...
Lee Sang-Rok - - 2013
Higenamine, also known as norcoclaurine, is an herbal constituent thought to act as a beta-2 adrenergic receptor agonist---possibly stimulating lipolysis. It was the purpose of this study to determine the impact of a higenamine-based dietary supplement on plasma free fatty acids and energy expenditure following acute oral ingestion. Sixteen healthy ...
Ambrosi Pierre - - 2013
How reliable is home blood pressure monitoring (HBPM) in heart transplant recipients is not known. Possibly, it may underestimate hypertensive burden, because blood pressure (BP) nondipper profile is frequent among these patients. This prospective study has been designed to determine whether HBPM adequately identifies hypertension in heart transplant recipients. We ...
Lackner Helmut K - - 2013
Since there are several popular beliefs about putative health benefits of amusement which are empirically substantiated poorly about putative health benefits of amusement, the immediate cardiovascular effects of amusement were studied in detail. Cardiovascular activity was studied while participants were viewing humorous films, relative to a control condition involving no ...
Cools Frank - - 2013
Regarding evaluation of drug-induced changes in left ventricular contractility in safety pharmacology there is still a gap in knowledge between preclinically and clinically used measurements. As a step towards translation of preclinical to clinical outcomes, this study in telemetered dogs was initiated to compare indexes of contractility, such as LV ...
Masutani Satoshi - - 2013
This study was undertaken to test the hypothesis that noninvasive echocardiographic indexes obtained using early diastolic mitral annular and inflow velocities reflect diastolic function in children. We included in this study 61 consecutive pediatric patients (age 0.4-13 years) who underwent cardiac catheterization for various heart diseases with biventricular circulation. Left ...
Lalan Shwetal S Division of Pediatric Nephrology, Children's Mercy Hospitals and Clinics, University of Missouri-Kansas City, Kansas City, MO, USA. Electronic address: - - 2014
Conflicting data exist regarding the accuracy of the oscillometric method of blood pressure (BP) measurement in neonates. There is limited data regarding intra-arterial BP trends in neonates. We aimed to determine the accuracy of oscillometric BP measurements and to evaluate the BP distributions in ill neonates. A total of 1492 ...
Stehlin Ellyce - - 2013
Measurements of left ventricular pressure (LVP) in conscious freely moving animals are uncommon yet could offer considerable opportunity for understanding cardiovascular disease progression and treatment. The aim of this study was to develop surgical methods and validate the measurements of a new high-fidelity solid-state pressure sensor telemetry device for chronically ...
Rama Chandran Suresh - - 2013
A 43-year-old man with history of rheumatic heart disease presented with a 2-month history of palpitations and breathlessness. On examination, the pulse was regular at 110 beats per minute, and the blood pressure was 180/40 mm Hg. He had a bounding carotid pulse (Corrigan's sign), a collapsing brachial pulse, pistol-shot ...
Wieser Martin - - 2013
Cardiovascular deconditioning has long been recognized as a characteristic of the physiological adaptation to long-term bed rest in patients. The process is thought to contribute to orthostatic intolerance and enhance secondary complications in a significant way. Mobilization is a cost-effective and simple method to maintain the cardiovascular parameters (i.e., blood ...
- - 2013
The Framingham Heart Study (FHS) has long been a beacon of biomedical research, yielding landmark findings on everything from the links between elevated blood pressure and stroke to the genetic risk factors underlying cardiac arrhythmias. Now, the fabled 65-year-long study of cardiovascular disease is the beacon of a more modern ...
Raj Rishi - - 2013
To determine the performance characteristics of gait speed measurements and the physiological cost index (PCI; heart rate change/gait speed) in working adults. Gait speeds, heart rate changes, andnon-steady state PCIs were calculated in 61 volunteers who worked in our health sciences center. These subjects completed 9 separate 100-foot walk tests ...
Gökdeniz Tayyar - - 2013
We aimed to evaluate the effects of non-dipper BP pattern on left ventricular (LV) rotational mechanics in hypertensive patients with type 2 diabetes mellitus (T2DM) with the utility of two-dimensional speckle tracking echocardiography (2D-STE). Eighty-six hypertensive patients with T2DM were enrolled. All patients underwent 2D-echocardiography and 24-h-ambulatory blood pressure monitoring. ...
Kishi Takuya - - 2013
Angiotensin II type 1 receptor (AT1R) blockers have various benefits on hypertension and/or heart failure. We demonstrated that telmisartan (TLM), an AT1R blocker, causes sympathoinhibition by reduction of reactive oxygen species (ROS) in the rostral ventrolateral medulla (RVLM) of stroke-prone spontaneously hypertensive rats (SHRSPs). The aim of this study was ...
Gupta Samir - - 2013
Controversy surrounds the assessment of perfusion and the methods currently utilised to define hypotension, especially blood pressure. There is growing agreement to assess heart function when selecting inotropic therapy and use bedside tools such as echocardiography for assessing at-risk infants. Both dopamine and dobutamine have comparative efficacy, and in certain ...
Beigel Roy - - 2013
When the right atrial pressure (RAP) exceeds the left atrial pressure, right-to-left shunting can occur. Normally, the Valsalva maneuver is used to facilitate elevation of RAP. However, performing the Valsalva maneuver can be problematic in certain situations. The aim of this study was to test the hypothesis that the application ...
Guazzi M - - 2013
Cardiorenal syndrome (CRS) is defined as an interaction of cardiac disease with renal dysfunction that leads to diuretic resistance and renal function worsening, mainly with heart failure (HF) exacerbation. Hemodynamic variables linking heart and kidney are renal blood flow (cardiac output) and perfusion pressure, i.e., the aortic - renal venous ...
Studinger Péter - - 2013
In this prospective, open-label, randomized, controlled clinical trial the effects of low-dose carvedilol, nebivolol, and metoprolol on central arterial pressure and augmentation index (AIx) and its heart rate-corrected value (AIx@75) were assessed. The authors randomized 75 hypertensive patients (18-70 years) to carvedilol 12.5/25 mg, metoprolol 50/100 mg, or nebivolol 2.5/5 mg daily and followed ...
Barst Robyn J - - 2013
Uncorrected congenital heart disease (CHD) frequently leads to pulmonary arterial hypertension (PAH), the most severe form of which is Eisenmenger syndrome (ES). We compared patients with idiopathic or heritable PAH (IPAH or HPAH; n = 1,626) against those with CHD-associated PAH (n = 353) who were enrolled in the Registry to Evaluate ...
Ennezat Pierre Vladimir - - 2013
Pulmonary hypertension (PH) is prevalent in decompensated heart failure with preserved ejection fraction (HFpEF). We investigated the effect of a return to a compensated state on pulmonary artery systolic pressure (PASP) and functional mitral regurgitation (FMR). Two-dimensional Doppler echocardiography was prospectively performed before initiation of standard therapy and 48 hours ...
Wang Yong-Ping - - 2013
Paced breathing is a frequently performed technique for cardiovascular autonomic studies. The relative timing of inspiration and expiration during paced breathing, however, is not consistent. We therefore examined whether indexes of heart rate variability and spontaneous baroreflex sensitivity would be affected by the respiratory time ratio that is set. We ...
Monroe Vanessa D - - 2013
Blood pressure lability is a phenomenon in which there is a wide range of extreme highs and lows in blood pressure measurements. These highs and lows occur at irregular intervals, and it is difficult for health care providers to isolate when this phenomenon occurs. Hypertension and hypotension occurring within minutes ...
Nicoara Alina - - 2013
Left ventricular diastolic dysfunction (LVDD) has only recently been recognized as an important determinant of perioperative morbidity. Intraoperative echocardiographers have been slow to adopt assessment of LVDD into clinical practice. This has been partly attributable to the complex measurements required to characterize LVDD, which are in turn related to how ...
Gopal Divya - - 2013
Aims and Objectives: Left internal mammary artery (LIMA) is the preferred arterial conduit for coronary artery bypass grafting. Various pharmacological agents are known to increase LIMA blood flow. Sympathetic blockade mediated by stellate ganglion block (SGB) has been used to provide vasodilatation in the upper extremities and in the treatment ...
Uzun H - - 2013
This study was designed to analyze the characteristics of adult patients with mad honey intoxication, with special emphasis on its effects on vital signs and blood glucose levels. Patients admitted to the Emergency Department of urban hospital in the Black Sea region of Turkey over the 16-months study period due ...
Kamalov German - - 2013
Cardinal pathologic features of hypertensive heart disease (HHD) include not only hypertrophied cardiomyocytes and foci of scattered microscopic scarring, a footprint of prior necrosis, but also small myocytes ensnared by fibrillar collagen where disuse atrophy with protein degradation would be predicted. Whether atrophic signaling is concordant with the appearance of ...
Huang Cheng-Hsiung - - 2013
Brief pressure overload of the left ventricle reduced myocardial infarct (MI) size in rabbits has been previously reported. Its effects in other species are not known. This study investigates effects of pressure overload and the role of adenosine in rats in this study. MI was induced by 40-minute occlusion of ...
Fujimoto Naoki - - 2013
Hypertension is associated with cardiovascular stiffening and left ventricular diastolic dysfunction, leading to comorbidities such as heart failure with preserved ejection fraction (HFpEF). It is unknown whether sex and hypertension subtype affect haemodynamics and left ventricular function in older individuals. Ninety-five older patients with Stage 1 hypertension (ambulatory awake SBP135-159 mmHg) ...
Manolis Athanasios - - 2013
Atrial fibrillation and arterial hypertension represent two common clinical conditions that frequently coexist, especially in older individuals, and are associated with increased risk of stroke. Antihypertensive therapy reduces the risk of stroke by approximately 40%. It has been observed that stroke rates were reduced by 10% for every 2-mmHg reduction ...
van den Hooven Edith H - - 2013
Early-life nutrition may influence cardiovascular development. Not much is known about the associations between dietary composition and cardiovascular risk factors in childhood. We examined the associations of infant macronutrient intake with cardiovascular structures and function in 2882 children participating in a prospective, population-based cohort study. Information on macronutrient intake at ...
Lampert Brent C - - 2013
Continuous flow (CF) left ventricular assist devices (LVAD) are afterload sensitive and therefore pump performance is affected by hypertension. In addition, poorly controlled hypertension may increase the risk of aortic insufficiency (AI) and stroke. Blood pressure regimens after CF LVAD have not been studied and their impact on rates of ...
Ke Youfu - - 2013
To evaluate the efficacy and safety of wuling powder and modified tianma gouteng decoction as an open add-on therapy for treating essential hypertension (EH). 72 cases of EH patients took wuling powder and modified tianma gouteng decoction for 2 weeks to treat EH without changing their former medication. New York ...
Spießhöfer Jens - - 2013
Using pulse transit time (PTT) and an ECG appears to be a promising alternative for invasive or noninvasive monitoring of blood pressure (BP). This study assessed the validity of PTT for BP monitoring in clinical practice. Twenty-nine patients with chronic heart failure (HF; 27 male, 70.5 ± 9.9 years) and nocturnal Cheyne-Stokes respiration ...
Arbo John E - - 2013
Right atrial pressure (RAP) is considered a surrogate for right ventricular filling pressure or cardiac preload. It is an important parameter for fluid management in patients with septic shock. It is commonly approximated by the central venous pressure (CVP) either invasively using a catheter placed in the superior vena cava ...
Masaki Mitsuru - - 2013
Plasma aldosterone concentration (PAC) is related to cardiac remodeling in patients with hypertension. However, we do not know the detailed relationship between changes in PAC and regression of left atrial (LA) volume following long-term treatment with angiotensin II receptor blocker (ARB) or calcium-channel blocker (CCB). The aim of this study ...
Eliasdottir Sigridur B - - 2013
Limited data exist on the comparison of blood pressure (BP) measurements using aneroid and oscillometric devices. The purpose of the study was to investigate the difference in BP obtained using oscillometric and aneroid BP monitors in 9- to 10-year-old children. A total of 979 children were divided into group O, ...
Fadel Bahaa M - - 2013
Careful analysis of the right-sided Doppler signals provides important data regarding right heart hemodynamics. Here, we illustrate the value of the combined analysis of flow across the hepatic vein, tricuspid valve, and pulmonary valve for the diagnosis of elevated right ventricular end-diastolic pressure.
Schroll Stephan - - 2013
Continuous positive airway pressure (CPAP) has been used to treat patients with chronic heart failure (CHF) and sleep-disordered breathing (SDB). CPAP treatment in severe CHF with concomitant SDB and atrial fibrillation has been linked to impairment of cardiac output (CO) as a potential cause for adverse outcome. The aim of ...
Welch Terrence D - - 2013
The surgical maze procedure is highly effective in treating symptomatic atrial fibrillation but may have detrimental effects on left atrial contractile function and compliance. We describe a series of patients presenting with symptomatic pulmonary hypertension due in part to left atrial dysfunction after surgical maze procedures. This report describes nine ...
Verma Anjali A Demonstrator, Department of Physiology, TMMC & RC , Moradabad, Uttar Pradesh, India - - 2013
Stress-induced increase in heart-rate and blood pressure is termed cardiovascular reactivity (CVR). Various studies are designed to monitor the CVR and use different types of experimental stressors. We have compared the CVR to three different stressors used in CVR based studies (cold pressor task, hand grip test, and video game) ...
Kunig H - - 2013
Ejection fractions, derived from ventricular volumes, and double product, related to myocardial oxygen consumption, are important diagnostic parameters, as they describe the efficiency with which oxygen is consumed. Present technology often allows only intermittent determination of physiological status. This deficiency may be overcome if ejection fractions and myocardial oxygen consumption ...
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