Search Results
Results 451 - 500 of 1702
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Giordano Ugo - - 2013
Hypertension and reduced HRV are frequent in heart-transplanted recipients. We studied 26 young recipients to investigate the relationship between BP and HRV during simultaneous 24-h monitoring. Presence of CAV was considered. All HRV measures were significantly lower than normal values. Significant correlations were found between mean daytime systolic BP and ...
Wong Yeun Ying - - 2013
Idiopathic pulmonary arterial hypertension (IPAH) results in increased right ventricular (RV) workload and oxygen demand. It has been shown that myocardial oxygen consumption (MVO2) of the hypertrophied right ventricle of IPAH patients can be measured using PET and (15)O-labeled tracers. This method is, however, not very suitable for routine clinical ...
Collins Helen E - - 2013
: Excitation-contraction coupling of the normotensive rat heart exhibits a time-of-day variation in its response to isoproterenol (ISO), with a decrease during the animal's active period. Pressure-induced hypertrophy is known to adversely affect the circadian clock in the heart and this study sets out to determine whether this alters the ...
Altunkan Sekip - - 2013
Impaired diastolic function and increased left ventricular mass are common findings in hypertensive patients and may occur early in the natural history of essential hypertension. In this study, we aimed to investigate the relationship between diastolic function parameters and coronary artery calcification (CAC) in hypertensive patients. The study was carried ...
Cave G - - 2013
Context. The use of intravenous lipid emulsion (ILE) as an antidote in non-local, anaesthetic drug toxicity has generated considerable interest. Flecainide is a lipophilic anti-arrhythmic with a significant cardiotoxic profile, with blockade of sodium and potassium channels causing arrhythmias and shock in severe toxicity. ILE has been proposed as a ...
Dupanović Mirsad - - 2013
The utility of dexmedetomidine (DEX) as an adjunct to conventional procedural sedation using midazolam and fentanyl was evaluated in 11 adult patients undergoing radiofrequency catheter ablation (RFCA) of atrial fibrillation. In a subsequent comparison to 11 demographically matched controls (n = 22) that previously received only midazolam- and fentanyl-based sedation, no significant ...
Chávez Elibet - - 2013
Introduction. The study of arterial hypertension risk factors in children guarantees the establishment of health policies to avoid complications associated with this illness in the future. The highest values of P-wave dispersion during sinus rhythm are pointed as predictors of atrial fibrillation in adulthood since there is an association between ...
Ruiz Paula - - 2013
This article presents a new device designed to simulate in vitro flow rates, pressures, and other parameters representing normal and diseased conditions of the human cardiovascular system. Such devices are sometimes called bioreactors or "mock" simulator of cardiovascular loops (SCVLs) in literature. Most SCVLs simulate the systemic circulation only and ...
Liu Ran - - 2013
Catestatin, a chromogranin A-derived peptide, is a potent antagonist of nicotine-evoked catecholamine release. We know that catecholamine plays an important role in cardiovascular remodeling induced by hypertension, therefore we hypothesized that catestatin would affect target-organ structure during hypertension. Twelve spontaneously hypertensive rats (SHRs) were randomized to SHR control group and ...
Cho Jung Sun - - 2013
This study was to investigate the feasibility of real-time 3-dimensional echocardiography (RT3DE) for the analysis of biventricular ejection fractions and volume measurements in patients with cor pulmonale and the correlations of RT3DE results with 64-slice multi-detector cardiac computed tomography (64-MDCT) results. This study included a total of 22 patients (59.3 ...
Chillo Pilly - - 2013
Aim. To assess prevalence, type and covariates of abnormal left ventricular (LV) geometry in untreated native Tanzanian patients with hypertension in relation to normotensive controls. Methods. Echocardiography was performed in 161 untreated hypertensive outpatients and 80 normotensive controls at a tertiary hospital in Tanzania. Hypertensive heart disease was defined as ...
Kurtz Abigail M - - 2013
STUDY OBJECTIVE: To evaluate the effects of a caffeinated 5-hour Energy shot compared with a decaffeinated 5-hour Energy shot as assessed by changes in blood pressure and heart rate in healthy, nonhypertensive volunteers. DESIGN: Randomized, double-blind, controlled, crossover study. SETTING: University campus. SUBJECTS: Twenty healthy volunteers. INTERVENTION: Subjects were randomized ...
Deftereos Spyridon - - 2013
There is substantial evidence that the autonomic system plays an important part in the pathogenesis of atrial fibrillation (AF). It appears that, although some patients have a preponderantly sympathetic or vagal overactivation leading to AF, a combined sympathovagal drive is most commonly responsible for AF triggering. The purpose of this ...
Vieira Fabiana Cavalcanti - - 2013
BACKGROUND AND PURPOSE: Patients with heart failure disease develop respiratory and functional limitations and suffer from the negative influence on their quality of life. This study was designed to evaluate respiratory muscle strength and its relationship to functional capacity, quality of life and rate of perceived exertion in patients with ...
Loukas Marios - - 2013
A double-chambered right ventricle is a rare heart defect in which the right ventricle is separated into a high-pressure proximal and low-pressure distal chamber. This defect is considered to be congenital and typically presents in infancy or childhood but has been reported to present rarely in adults. It can be ...
Sztrymf Benjamin - - 2013
The Complior device (Alam Medical, France) has contributed to the rise of arterial stiffness as a measure of cardiovascular risk. In its latest version (Complior Analyse) the sensor records pressure instead of distension waveforms thus allowing the measurement of central pressure and pulse wave analysis. The aim of our study ...
Lucas Samuel J E - - 2013
Endogenous oscillations in blood pressure and cerebral blood flow have been associated with improved orthostatic tolerance. Although slow breathing induces such responses, it has not been tested as a therapeutic strategy to improve orthostatic tolerance. Utilising a randomized crossover, sham-controlled design, we tested the hypothesis that breathing at 6 breaths⋅min(-1) ...
Guihaire Julien - - 2013
AIMS: To investigate the physiological correlates of indices of RV function in a model of chronic pressure overload. METHODS AND RESULTS: Chronic pulmonary hypertension (PH) was induced in piglets by ligation of the left pulmonary artery (PA) followed by weekly embolization of right lower lobe arteries for 5 weeks (the ...
Perry Blake G - - 2013
Lower body positive pressure (LBPP) has been used in the treatment of haemorrhagic shock and in offsetting g-force induced fluid shifts. However, the middle cerebral artery blood flow velocity (MCAv) response to supine LBPP is unknown. Fifteen healthy volunteers (mean ± SD: age, 26 ± 5 year; body mass, 79 ± 10 kg; height, 174 ± 9 cm) completed 5 minutes of ...
Grossman Alon A Israeli Air Force Aero Medical Center, Tel Hashomer, Israel. - - 2013
The prevalence and magnitude of inter-arm BP difference (IAD) in young healthy patients is not well characterized. Flight academy applicants and designated aviators undergo annual evaluation that includes blood pressure (BP) measurement on both arms. All BP measurements performed from January 1, 2012, to April 30, 2012, were recorded and ...
Blanton Robert M RM Tufts Medical Center, Molecular Cardiology Research Institute, 800 Washington Street, Box 80, Boston, MA 02111. - - 2013
Hypertensive heart disease causes significant mortality in older patients, yet there is an incomplete understanding of molecular mechanisms that regulate age-dependent hypertensive left ventricular hypertrophy (LVH). Therefore, we tested the hypothesis that the cGMP-dependent protein kinase G I alpha (PKGIα) attenuates hypertensive LVH by evaluating the cardiac phenotype in mice ...
Marketou Maria E - - 2013
BACKGROUND: Hypertensive populations suffer from an increased susceptibility to ventricular arrhythmias and sudden cardiac death. A high-salt diet appears to be a major factor involved in cardiovascular complications in hypertension. We examined the relationship between dietary salt and potassium, as indicated by urinary sodium (UNa), urinary potassium (UK), and urinary ...
Palatini Paolo - - 2013
Resting heart rate is a well recognized marker of autonomic nervous system tone, and in many population studies has been found to be a significant correlate of blood pressure, increased body mass index, and metabolic disturbances. This association is particularly striking in patients with hypertension or diabetes, and cardiovascular morbidity ...
Kollias Anastasios - - 2013
Hypertension and atrial fibrillation (AF) often coexist and are strong risk factors for stroke. Current guidelines for blood pressure (BP) measurement in AF recommend repeated measurements using the auscultatory method, whereas the accuracy of the automated devices is regarded as questionable. This review presents the current evidence on the feasibility ...
Saponaro V - - 2013
The aim of this study was to compare the cardiovascular effects of medetomidine, acepromazine and their combination administered intravenously in healthy dogs. Ten dogs were included in this study and randomly assigned to the three different sedative protocols: medetomidine (2μg/kg, protocol M), acepromazine (20μg/kg, protocol A) and acepromazine followed by ...
Huang Huan - - 2013
Pulsatile left ventricular assist devices (LVADs) driven by electric motors have been widely accepted as a treatment of heart failure. Performance enhancement with computer assistance for this kind of LVAD has seldom been reported. In this article, a numerical method is proposed to assist the design of a cam-type pump. ...
Hu Y - - 2013
The purpose of this study was to explore the relationship between left ventricular (LV) dysfunction and arterial wall stiffening. A total of 218 patients over the age of 45 diagnosed with hypertension in Jinan City and hospitalised between 2010 and 2011 were included in this study. LV function was evaluated ...
Barrios Vivencio - - 2013
Hypertension is the most frequent condition associated with atrial fibrillation (AF) and stroke, the most terrible complication of AF. Achieving blood pressure (BP) goals as well as an adequate antithrombotic treatment are critical to reduce the incidence of stroke. But are interactions between anticoagulants and antihypertensive agents relevant for achieving ...
Ptak Judy A - - 2013
We describe a case of a 46-yr-old female who developed hypertension, tachycardia, dysarthria, and leg weakness provoked by pressure changes associated with flying. Typically during the landing phase of flight, she would feel dizzy and note that she had difficulty with speech and leg weakness. After the flight the leg ...
Chemla Denis - - 2013
The mean pulmonary artery pressure (mPAP) replaces mean systolic ejection pressure (msePAP) in the classic formula of right ventricular stroke work (RVSW) = (mPAP - RAP) × stroke volume, where RAP is mean right atrial pressure. Only the steady work is thus taken into account, not the pulsatile work, whereas ...
Al Bannay Rashed - - 2013
OBJECTIVE: To study the clinical significance of presenting blood pressure parameters and heart rate in patients with hypertensive crisis. METHODS: In patients admitted with hypertensive crisis between January 2011 and May 2011, demography, mode of presentation, co-morbidities, blood pressure readings, and heart rate at presentation were documented. Further clustering of ...
Lu Zhibing - - 2013
BACKGROUND: The underlying mechanism of atrial fibrillation (AF) in association with hypoxia remains unclear. This study aimed to investigate the AF vulnerability in an acute intermittent hypoxia model and ascertained the mechanism. METHODS AND RESULTS: In 15 anesthetized open-chest dogs (10 experimental and 5 control), multiple-electrode catheters were sutured to ...
Campbell Tavis S - - 2013
BACKGROUND: The experience of low socioeconomic position in childhood may increase risk for adult cardiovascular disease above and beyond the effects of current socioeconomic position. One limitation of most previous research is that childhood socioeconomic position was assessed retrospectively. METHODS: Measures of ambulatory blood pressure, heart rate, and heart rate ...
Muiesan Maria Lorenza - - 2013
Cardiovascular (CV) complications such as myocardial infarction, heart failure, stroke and renal failure are related to both the degree and the duration of blood pressure (BP) increase. Resistant hypertension (RH) is associated with a higher risk of CV complications and a higher prevalence of target organ damage (TOD). The relationship ...
Schmeisser Alexander - - 2013
Pulmonary hypertension (PH) due to left heart disease is classified as group II according to the Dana Point classification, which includes left ventricular systolic and/or diastolic left heart failure, and left-sided valvular disease. PH due to left heart disease is the most common cause and when present, especially with right ...
Brown Daniel K - - 2013
A randomized cross-over study explored whether viewing different scenes prior to a stressor altered autonomic function during the recovery from the stressor. The two scenes were a) nature (composed of trees, grass, fields) or b) built (composed of man-made, urban scenes lacking natural characteristics) environments. Autonomic function was assessed using ...
Alam Mahboob - - 2013
The acute impact of hypertensive crisis, and changes after treatment, on left ventricular (LV) systolic and diastolic function using comprehensive echocardiography, including speckle tracking, has not been well characterized. Thirty consecutive patients admitted to the hospital from the emergency room with hypertensive crisis underwent Doppler echocardiography at baseline and after ...
Linz Dominik - - 2013
INTRODUCTION: This study was designed to compare the effect of electrical baroreflex stimulation (BRS) at an intensity used in hypertensive patients and renal denervation (RDN) on atrial electrophysiology. BRS and RDN reduce blood pressure and global sympathetic drive in patients with resistant hypertension. Whereas RDN decreases sympathetic renal afferent nerve ...
Larsson Gunilla - - 2013
The aim of this study was to investigate orthostatic reactions in females with Rett syndrome (RTT), and also whether the severity of the syndrome had an impact on autonomic reactions. Based on signs of impaired function of the central autonomic system found in RTT, it could be suspected that orthostatic ...
Pu Min - - 2013
BACKGROUND: -Mitral regurgitation (MR) produces sympathetic nervous system activation which is detrimental in other causes of heart failure. However, whether β-blockade is beneficial in MR has not been determined. METHODS AND RESULTS: -Eighty-seven rats with significant organic MR were randomized to the β-blockade group (n=43) or the control group (n=44). ...
Andersen Asger - - 2013
BACKGROUND:: We investigated if soluble guanylate cyclase stimulation either alone or in combination with PDE5 inhibition could prevent pressure overload induced right ventricular hypertrophy and failure. METHODS AND RESULTS:: The soluble guanylate cyclase stimulator BAY 41-2272 (BAY, 10 mg/kg/day) either alone or in combination (BAY+SIL) with a PDE5 inhibitor sildenafil ...
Kako Hiromi - - 2013
BACKGROUND: During perioperative care, the continuous measurement of blood pressure (BP) provides superior physiologic monitoring to intermittent techniques. However, such monitoring requires placement of an intraarterial catheter, which may be time-consuming or associated with adverse events and technical difficulty. A noninvasive, continuous BP monitoring device has been studied in the ...
Joffe Samuel W - - 2013
Hypertension is a major risk factor in the development of heart failure (HF), yet current guidelines do not specify a target blood pressure (BP) for patients with established systolic or diastolic left ventricular (LV) dysfunction. While no randomized controlled trial (RCT) has been conducted to specify the optimal blood pressure ...
Możdżan Monika - - 2013
Long-lasting arterial hypertension causes left ventricular hypertrophy (LVH) and impairs left ventricular diastolic function. Our aim was to compare echocardiographic parameters between hypertensive patients defined as dippers and non-dippers during ambulatory blood pressure (BP) monitoring. We analysed 61 consecutive subjects with treated hypertension undergoing 24-h BP monitoring and transthoracic echocardiographic ...
Kallem Radhakrishna R - - 2013
There are limited data in the literature comparing two simultaneously worn ambulatory blood pressure (BP) monitoring (ABPM) devices. The authors compared BPs from two monitors (Mobil-O-Graph [I.E.M., Stolberg, Germany] and Spacelabs 90207 [Spacelabs Medical, Issequah, WA]). In the nonrandomized component of the study, simultaneous 8-hour BP and heart rate data ...
Toischer Karl K Abt. Kardiologie und Pneumologie/Herzzentrum, Georg-August-Universität Göttingen, - - 2013
The aim of the study was to determine the characteristics of the late Na current (INaL) and its arrhythmogenic potential in the progression of pressure-induced heart disease. Transverse aortic constriction (TAC) was used to induce pressure overload in mice. After one week the hearts developed isolated hypertrophy with preserved systolic ...
Murphy Olive H - - 2013
In this paper, the development of a fully implantable wireless sensor able to provide continuous real-time accurate pressure measurements is presented. Surface Acoustic Wave (SAW) technology was used to deposit resonators on crystalline quartz wafers; the wafers were then assembled to produce a pressure sensitive device. Excitation and reading via ...
Watanabe Takatomo - - 2013
We assessed the hypothesis that blood pressure (BP)-lowering therapy has a beneficial effect on left atrial (LA) structure and function and may decrease the incidence of new-onset atrial fibrillation (AF) in elderly patients with hypertension (HTN). We divided 234 subjects 65 years old into four groups based on mean office ...
Patel Vaibhav B - - 2013
Rationale: The classical phagocyte NADPH oxidase (gp91(phox) or Nox2) is expressed in the heart. Nox2 activation requires membrane translocation of the p47(phox) subunit and is linked to heart failure. We hypothesized that loss of p47(phox) subunit will result in decreased ROS production and resistance to heart failure. Objective: To define ...
Yamauchi Hiroyuki - - 2013
The occurrence of heart failure (HF) and its clinical features after a great disaster have not been rigorously examined. We retrospectively examined the effect of the Great East Japan Earthquake on the occurrence of decompensated HF. The number of patients admitted for treatment of decompensated HF and their clinical features ...
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