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Franceschini Nora N Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, 137 E. Franklin St., Suite 306, Chapel Hill, NC, USA, - - 2014
Hypertension is the most common chronic condition seen by physicians in ambulatory care and a condition for which life-long medications are commonly prescribed. There is evidence for genetic factors influencing blood pressure variation in populations and response to medications. This review summarizes recent genetic discoveries that surround blood pressure, hypertension, ...
Balfour Pelbreton C PC Jr Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, - - 2014
Despite remarkable declines in US cardiovascular disease morbidity and mortality over the last several decades, the prevalence of risk factors such as type 2 diabetes and hypertension remains high, associated with increasing obesity rates. Although optimal glycemic control remains a primary focus to decrease the disease burden, the FDA has ...
Whelton Paul K PK Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 440 Walnut Street, New Orleans, LA, 70118, USA, - - 2014
The scientific underpinning for recommended levels of dietary sodium and potassium intake is of great importance to healthcare providers and policy decision-makers. Recent clinical trials and meta-analyses confirm the capacity of dietary sodium reduction and potassium supplementation to reduce blood pressure with no harmful effects on blood lipid levels in ...
Bangsbo J J Copenhagen Centre for Team Sport and Health, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, - - 2014
This supplement contains 16 original articles describing how football conducted as small sided games affects fitness and health of untrained individuals across the lifespan. The intermittent nature of football and high exercise intensity result in a broad range of effects. The heart changes its structure and improves its function. Blood ...
McCloskey K K 1Child Health Research Unit,Barwon - - 2014
Childhood cardiovascular risk factors affect vascular function long before overt cardiovascular disease. Twin studies provide a unique opportunity to examine the influence of shared genetic and environmental influences on childhood cardiovascular function. We examined the relationship between birth parameters, markers of adiposity, insulin resistance, lipid profile and blood pressure and ...
Mazza A A Department of Internal Medicine, Santa Maria della Misericordia Hospital, Rovigo, Italy - - - 2014
Glomerular filtration rate (GFR) is commonly calculated using the modification of diet in renal disease (MDRD) and Cockroft-Gault (CG) formulas and recently by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) algorithm and not directly measured, so that the real impact of antihypertensive therapy on GFR could not be well defined. ...
Krakoff Lawrence R LR Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: - - 2014
A report from panel members appointed to the Eighth Joint National Committee titled "2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults" has garnered much attention due to its major change in recommendations for hypertension treatment for patients ≥60 years of age and for their treatment goal. In response, ...
Barbaro Natália Ruggeri NR Laboratory of Cardiovascular Pharmacology, Faculty of Medical Sciences, University of Campinas (Unicamp) , Campinas , - - 2014
Background. Increased levels of inflammatory biomarkers such as interleukin-6 (IL-6), 10 (IL-10), 1β (IL-1β), tumor necrosis factor-α (TNF-α) high-sensitivity C-reactive protein (hs-CRP) are associated with arterial stiffness in hypertension. Indeed, resistant hypertension (RHTN) leads to unfavorable prognosis attributed to poor blood pressure (BP) control and target organ damage. This study ...
Tyrovolas Stefanos S Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, - - 2014
The aim of this work was to evaluate factors associated with arterial blood pressure in a sample of older Mediterranean people without known cardiovascular disease. During 2005 to 2011, 2813 older (aged 65-100 years) individuals from 22 Mediterranean islands and the rural Mani region (Peloponnesus) voluntarily enrolled. Standard procedures were used ...
Chirinos Julio A JA University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Philadelphia VA Medical Center, Philadelphia, PA - - 2014
-Chronic kidney disease (CKD) is associated with an increased risk of heart failure (HF). We aimed to evaluate the role of large artery stiffness, brachial and central blood pressure as predictors of incident hospitalized HF in the Chronic Renal Insufficiency Cohort (CRIC), a multi-ethnic multi-center prospective observational study of patients ...
Zhao Leilei L Department of Cardiovascular-Internal Medicine, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang, - - 2014
This study aimed to quantitatively evaluate the predictive value of brachial pulse pressure and cardiovascular or all-cause mortality in the general population based on prospective observational studies by conducting a meta-analysis. Only prospective observational studies investigating baseline brachial pulse pressure and cardiovascular or all-cause mortality risk were selected from PubMed ...
Amer Muhammad M Department of Medicine, Johns Hopkins University, Baltimore, Maryland, - - 2014
Inverse association between lower level of 25-hydroxyvitamin D [25(OH)D] and higher prevalence of peripheral arterial disease (PAD) among individuals with cardiovascular diseases (CVD) is known. Less is known about the relationship between 25(OH)D and ankle-brachial blood pressure index (ABPI) in asymptomatic adults. We hypothesized a nonlinear relationship between 25(OH)D and ...
Santiago Luiz Miguel LM Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal; USF Topázio, ACES Baixo Mondego, ARS do Centro IP, Coimbra, Portugal. Electronic address: - - 2014
To study the differences between controlled and uncontrolled hypertensive patients. This was a cross-sectional observational study of the hypertensive population on the lists of three general practitioners in the district of Coimbra in central Portugal in 2013, with a margin of error of 6% and 95% confidence interval in each ...
Gać Paweł - - 2014
INTRODUCTION A relationship between environmental exposure to cigarette smoke and blood pressure remains to be insufficiently recognised. OBJECTIVES The study aimed at evaluation of effects exerted by environmental exposure to cigarette smoke on blood pressure in patients with essential hypertension (ET). PATIENTS AND METHODS The study was conducted on 39 patients with ET ...
Wei Shubo S State Key Laboratory of Superhard Materials, Jilin University, Changchun 130012, China. - - 2014
The high-symmetry cubic cesium chloride (CsCl) structure with a space group of Pm3[combining macron]m (Z = 1) is one of the prototypical AB-type compounds, which is shared with cesium halides and many binary metallic alloys. The study of high-pressure evolution of the CsCl phase is of fundamental importance in helping ...
Anderson Robert J RJ Endocrinology, Veterans Affairs Medical Center, Omaha, NE - - 2014
Blood pressure (BP) control for renal protection is essential for patients with type 2 diabetes. Our objective in this analysis of Veterans Affairs Diabetes Trial (VADT) data was to learn whether on-study systolic BP (SBP), diastolic BP (DBP), and pulse pressure (PP) affected renal outcomes measured as albumin-to-creatinine ratio (ACR) ...
Kieneker Lyanne M LM From the Top Institute Food and Nutrition, Wageningen, The Netherlands (L.M.K., S.J.L.B., M.M.J.); Departments of Internal Medicine (L.M.K., R.T.G., G.N., S.J.L.B., M.M.J.) and Cardiology (R.A.d.B.), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Health Sciences, VU University Amsterdam, Amsterdam, The Netherlands (L.M.K.); and Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA - - 2014
Previous prospective cohort studies on the association between potassium intake and risk of hypertension have almost exclusively relied on self-reported dietary data, whereas repeated 24-hour urine excretions, as estimate of dietary uptake, may provide a more objective and quantitative estimate of this association. Risk of hypertension (defined as blood pressure ...
Khalesi Saman S From the Griffith Health Institute (S.K., J.S., N.B.) and School of Medicine (S.K., J.S., R.J.), Griffith University, Australia; and Australia and Cardiac Services/Cardiology, Gold Coast Health, Australia - - 2014
Previous human clinical trials have shown that probiotic consumption may improve blood pressure (BP) control. The aim of the present systematic review was to clarify the effects of probiotics on BP using a meta-analysis of randomized, controlled trials. PubMed, Scopus, Cochrane Library (Central), Physiotherapy Evidence Database, and Clinicaltrial.gov databases were ...
Kimmoun Antoine - - 2014
To the Editor: As noted by Asfar et al. (April 24 issue),(1) a major concern related to targeting a relatively low mean arterial blood pressure in patients with septic shock is that the brain is at risk for ischemia in this condition. The risk of potential brain ischemia is particularly ...
Kirkpatrick Andrew W - - 2014
To the Editor: As noted by Asfar et al. (April 24 issue),(1) a major concern related to targeting a relatively low mean arterial blood pressure in patients with septic shock is that the brain is at risk for ischemia in this condition. The risk of potential brain ischemia is particularly ...
Berg Ronan M G - - 2014
To the Editor: As noted by Asfar et al. (April 24 issue),(1) a major concern related to targeting a relatively low mean arterial blood pressure in patients with septic shock is that the brain is at risk for ischemia in this condition. The risk of potential brain ischemia is particularly ...
- - 2014
To the Editor: As noted by Asfar et al. (April 24 issue),(1) a major concern related to targeting a relatively low mean arterial blood pressure in patients with septic shock is that the brain is at risk for ischemia in this condition. The risk of potential brain ischemia is particularly ...
Montero-Perez-Barquero Manuel M Department of Internal Medicine, IMIBIC/Hospital Reina Sofia de Córdoba, University of Córdoba, - - 2014
There is limited information about the effects of beta-blockers in heart failure (HF) stratified by blood pressure, especially in the elderly and those with preserved EF. We evaluate the effects of nebivolol on outcomes in elderly patients with HF stratified by baseline systolic blood pressure (SBP) and EF. The SENIORS ...
Sohn Min-Woong MW Center of Innovation for Complex Chronic Healthcare, Hines VA Hospital, Hines, IL; Feinberg School of Medicine, Northwestern University, Chicago, IL. Electronic address: - - 2014
To examine the association between sedentary behavior and BP among Osteoarthritis Initiative (OAI) participants. We conducted a cross-sectional analysis of the OAI 48-month visit participants whose physical activity was measured using accelerometers. Participants were classified into four quartiles according to the percentage of wear time that was sedentary (<100 activity ...
Langefeld Carl D CD 1] Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA [2] Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, North Carolina, - - 2014
Apolipoprotein L1 gene (APOL1) G1 and G2 coding variants are strongly associated with chronic kidney disease (CKD) in African Americans (AAs). Here APOL1 association was tested with baseline estimated glomerular filtration rate (eGFR), urine albumin:creatinine ratio (UACR), and prevalent cardiovascular disease (CVD) in 2571 AAs from the Systolic Blood Pressure ...
Aribas Alpay A Department of Cardiology, Necmettin Erbakan University Meram School of Medicine , Meram, Konya , - - 2014
Background. Endothelial dysfunction plays a major role in erectile dysfunction (ED). Uric acid (UA) is a marker of endothelial dysfunction. We hypothesized that increased UA levels may be associated with ED and aimed to investigate whether there is a relationship between, UA and ED in hypertensive patients. Methods. A total ...
Bushnik Tracey T Health Analysis Division, Statistics Canada, Ottawa, Ontario - - 2014
Hypertension is the leading risk factor for cardiovascular disease, but its cause is not always known. Interest is increasing in the potential role of environmental chemicals, including lead. Data are from the first two cycles of the Canadian Health Measures Survey. Lead in whole blood (PbB), and systolic (SBP) and ...
Terracciano Antonio A aFlorida State University College of Medicine, Tallahassee, Florida bNational Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA cHospital San Raffaele Pisana IRCCS, Rome dIstituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche eUnità Operativa Complessa Cardiologia, Presidio Ospedaliero A. Businco, Cagliari, - - 2014
Anxiety and other psychological dispositions are thought to be associated with blood pressure. This study tests whether personality traits have long-term associations with masked and white-coat effects. A community-based sample of 2838 adults from Sardinia (Italy) completed the Revised NEO Personality Inventory, and 7 years later, blood pressure was assessed ...
Akça Omer Faruk OF Assistant Professor, Necmettin Erbakan University, Meram School of Medicine, Department of Child and Adolescent Psychiatry, Konya, - - 2014
Anxiety sensitivity (AS) is a relatively stable dispositional variable that may increase the risk for anxiety-related symptoms, particularly panic attacks, among individuals of all age groups. However, changes in AS during adolescence in healthy individuals has not been previously investigated. We aimed to investigate the relationship of AS levels with ...
Tatsumi Kazuhiro K Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, 650-0017, - - 2014
Early diastolic mitral inflow and annulus velocities ratio (E/e') is the parameter used to estimate left ventricular (LV) filling pressure, but their use for patients with reduced ejection fraction (EF) (<50 %) is controversial. LV endocardial area change rate with 3-dimensional (3-D) speckle-tracking can be used to evaluate the entire LV ...
Lee Sunghee S aInstitute of Human Genomic Study, School of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea bDepartment of Medicine, Division of Pulmonary, Critical care & Sleep, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA cDepartment of Radiology, School of Medicine, Korea University, Ansan Hospital, Ansan dDepartment of Foods and Nutrition, College of Natural Sciences, Kookmin University, Seoul eDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam fDivision of Pulmonary, Sleep and Critical Care Medicine, Department of Internal Medicine, Korea University, Ansan Hospital, Ansan, Republic of - - 2014
A reverse dipping pattern, characterized by higher night-time blood pressure (BP) than daytime BP, is associated with the increased risk for cerebrovascular disease, cardiovascular events and all-cause mortality. However, little has known about the association between white matter change (WMC) and reverse dipping pattern, particularly in normotensive adults. We aimed ...
Khader A A United Nations Relief and Works Agency for Palestine Refugees in the Near East, Amman, - - 2014
In six United Nations Relief and Works Agency (UNRWA) primary health care clinics in Jordan serving Palestine refugees diagnosed with hypertension, to determine the number, characteristics, programme outcomes and measures of disease control for those registered up to 30 June, 2013, and in those who attended clinic in the second ...
Matsumoto Yuuki - - 2014
Thermodynamic stability boundary in the structure-H methane+bromocyclopentane mixed hydrate system was measured at pressures from 20 MPa to 100 MPa. The thermodynamic stability boundary of the methane+bromocyclopentane mixed hydrate exhibits anomalous behavior under conditions at high pressures and high temperatures. This phenomenon is due to the elimination and substitution reactions ...
Kalish Brian T BT Harvard Medical School, Boston, MA, United States. Electronic address: - - 2014
Childhood blood pressure (BP) is an important determinant of adult cardiovascular disease. Prenatal exposure to methylmercury through maternal fish consumption has been reported to increase the BP of children years later. Mother-child pairs were enrolled from Project Viva, a prospective cohort study in Massachusetts. From second trimester maternal blood samples, ...
Cao Zhongqiang Z aMOE Key Lab of Environment and Health bDepartment of Maternal and Child Health cDepartment of Social Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan dDongfeng General Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan, - - 2014
Evidence from epidemiological studies suggested that shorter and longer duration of nocturnal sleeping may increase the risk of hypertension for older adults. Little is known about the duration of midday nap on the variability of blood pressure among older adults. In this study, we examined whether duration of habitual midday ...
Hirayama Atsushi A Department of Cardiology, Pulmonology and Nephrology, Yamagata University School of Medicine, Yamagata, - - 2014
Recent studies have suggested that urine albumin excretion in the high normal range predicts hypertension. However, the relationship between urinary albumin excretion in spot urine and incident hypertension remains unclear in the general Japanese population. To clarify this relationship, we conducted a cohort study in a community-based population of 412 ...
Strandberg Arto Y AY aDepartment of Medicine, Geriatric Clinic, University of Helsinki, and Helsinki University Central Hospital bInstitute of Health Sciences/Geriatrics, University of Oulu, and Oulu University Hospital, Oulu cDepartment of Public Health, University of Turku, Turku dTHL-National Institute for Health and Welfare eUnit of General Practice, Helsinki University Central Hospital fDepartment of General Practice, University of Helsinki, Helsinki, - - 2014
The aim of the present study was to examine the long-term impact of midlife blood pressure (BP) on mortality, comorbidity, and health-related quality of life (HRQoL) in old age. These are longitudinal analyses of the Helsinki Businessmen Study, a cohort of business executives, born in 1919-1934, whose BP was measured ...
Foraster Maria M Centre for Research in Environmental Epidemiology (CREAL); CIBER Epidemiología y Salud Pública (CIBERESP); Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut (UPF), Barcelona, - - 2014
Traffic noise has been associated with prevalence of hypertension, but reports are inconsistent for blood pressure (BP). People's noise exposure indoors might be essential to ascertain effects and disentangle them from those suspected for traffic-related air pollution. We analyzed associations of long-term exposure to indoor traffic noise at bedrooms with ...
Higgins Timothy P TP School of Biosciences, Cardiff University, Cardiff, United - - 2014
Hypertension, decreased glucose tolerance, adverse lipid profiles and low physical activity levels are associated with increased type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk. High intensity interval training (HIIT), a low volume, reduced time, high intensity programme, may be a useful alternative to current government guidelines which specify ...
Villela Patrícia Teixeira Meirelles PT Division of General Internal Medicine and Geriatrics, Ribeirão Preto Medical School, University of São Paulo-FMRP-USP, Ribeirão Preto, SP, - - 2014
The aim of this study was to evaluate the preference for salt in hypertensive and normotensive older individuals. Hypertensive (group 1: n=32, aged 73.7±6.3 years) or normotensive patients (group 2: n=26, aged 71.5±8.0 years) were submitted to a test to determine their preference for bread samples with different salt concentrations: 1.5%, 2.0% ...
Chia Yook Chin - - 2014
Patients with resistant hypertension are subjected to a higher risk of getting stroke, myocardial infarction, congestive heart failure and renal failure. However, the exact prevalence of resistant hypertension in treated hypertensive patients in Malaysia is not known. This paper examines the prevalence and determinants of resistant hypertension in a sample ...
Manios Efstathios E Department of Clinical Therapeutics, Medical School of Athens, Alexandra Hospital, Athens, - - 2014
Several studies have shown that blood pressure (BP) variability derived from ambulatory blood pressure monitoring (ABPM) is associated with target organ damage development. However, the use of discontinuous ABPM to assess rapid BP changes is unavoidably limited by the long frequency at which automated measures are scheduled. The aim of ...
Lu N N The Pediatric Cardiology, The First Hospital of Jilin University, Changchun, - - 2014
To explore the association between the dopamine β-hydroxylase (DBH) gene C-1021T polymorphism and the occurrence of orthostatic hypotension (OH) in Chinese patients, the DBH C-1021T polymorphism was genotyped in 317 patients with OH and 664 age- and sex-matched controls with orthostatic normotension. All subjects underwent an upright posture study for ...
Bizzarro Matthew M Department of Pediatrics, Yale University School of Medicine, 333 Cedar Street WP493, P.O. Box 208064, New Haven, CT, USA, - - 2014
Nitric oxide (NO) is a prevalent molecule in humans that is responsible for many physiologic activities including pulmonary vasodilation. An exogenous, inhaled form (iNO) exists that mimics this action without affecting systemic blood pressure. This therapy has been implemented in the treatment of pulmonary hypertension. This review examines the efficacy ...
Smith L P LP Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, - - 2014
Hispanics comprise the most rapidly growing demographic in the US, but little is known about the cardiometabolic risk factors in Hispanic children. This study examined the association of high waist circumference (WC) and elevated blood pressure by race/ethnicity in a cohort of 9 to 13 year olds in New Haven, ...
Juraschek Stephen P SP School of Medicine, John Hopkins University, Baltimore, Maryland; Johns Hopkins Bloomberg School of Public Health and Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland; Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, - - 2014
Recent evidence suggests that insufficient oxidative capacity or mitochondrial dysfunction may play a causal role in the development of high blood pressure. However, this hypothesis has not been tested in the general population. We hypothesized that lactate, a measure of oxidative capacity, would be positively associated with incident hypertension even ...
Bang Casper N CN Department of Medicine, Weill Cornell Medical College, NY, USA; Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen Denmark. Electronic address: - - 2014
Cornell product criteria, Sokolow-Lyon voltage criteria and electrocardiographic (ECG) strain (secondary ST-T abnormalities) are markers for left ventricular hypertrophy (LVH) and adverse prognosis in population studies. However, the relationship of regression of ECG LVH and strain during antihypertensive therapy to cardiovascular (CV) risk was unclear before the Losartan Intervention for ...
Hu Dayi D Department of Cardiology, Peking University People's Hospital, Beijing, 100044, China, - - 2014
Single-pill combination (SPC) therapy of two drugs is recommended by international guidelines, including the Chinese guidelines (2010), for the treatment of hypertension in high-risk patients who require marked blood pressure (BP) reductions. Real-world data on the efficacy and safety of valsartan/amlodipine (Val/Aml) SPC are scarce. The present study is the ...
Masugata Hisashi H Department of Integrated Medicine, Kagawa University, Miki, Kagawa 761-0793, - - 2014
The present study aimed to investigate the association between plasma brain natriuretic peptide (BNP) levels and systolic blood pressure (SBP) variability over a one-year period. Blood pressure was measured in 44 patients treated for hypertension (73±9 years old) at an outpatient clinic every one to two months over a one-year ...
Li Yongling - - 2014
Background: Workers coming from lowland regions are at risk of developing acute mountain sickness (AMS) when working in low oxygen high-altitude areas. Objectives: The aim of this study was to improve the conditions that lead to hypoxia and ensure the safety of the high-altitude workers. We analyzed the influence of ...
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