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Results 401 - 450 of 3939
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Chen Jinfeng J Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 210029, - - 2014
Fibrillin-1 (FBN1) was reported to have impact on the physiological arterial stiffness and vascular remodeling with hypertension of recent years. In the previous study we reported the association of four functional single nucleotide polymorphisms (SNPs) of FBN1 gene and hypertension. Here, we further investigate the association of four tagging SNPs ...
Shimoji Keigo K Department of Radiology, National Center of Neurology and Psychiatry Hospital, Kodaira, Tokyo, 187-8551, Japan, - - 2014
Hypertension is associated with substantial morbidity in Japan. The aim of this work was to evaluate whether hypertension is associated with white matter microstructural changes by using diffusional kurtosis imaging (DKI). We explored the regional patterns of white matter alteration in 15 hypertensive middle-aged male participants and 11 normotensive controls ...
Lind P Monica PM Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Ulleråkersvägen 40, 751 85 Uppsala, Sweden. Electronic address: - - 2014
Polychlorinated biphenyls (PCBs) and dioxin given to experimental animals increase the blood pressure. We therefore investigated if circulating levels of persistent organic pollutants (POPs) were related to hypertension in a population-based sample of men and women. One thousand and sixteen subjects aged 70 years were investigated in the Prospective Investigation ...
Choi Suk-Won SW Division of Cardiology, Hallym University, Dongtan Sacred Heart Hospital, Hwaseong, Republic of - - 2014
There are limited data about characteristics of hypertension subtypes in Asian hypertensive patients and their impacts on treatment of hypertension. This prospective, multi-center, observational study evaluated 2439 hypertensive patients. (≥60 years) Inadequately controlled and drug-naïve patients were categorized into three hypertension subtypes (isolated systolic hypertension [ISH], combined systolic/diastolic hypertension [SDH], and ...
Rebellato Andrea A Department of Medicine-DIMED, Clinica Medica 3, University of Padova, Via Giustiniani 2, 35128, Padua, - - 2014
Cushing's syndrome is associated with high cardiovascular morbility and mortality. Blood pressure (BP) variability within a 24-h period is increasingly recognized as an independent predictor of cardiovascular risk. The aim of our study was to investigate the short-term BP variability indices in Cushing's syndrome. Twenty-five patients with Cushing's syndrome (mean ...
Regnault Nolwenn N Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, MRC Epidemiology Unit, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, USA and Department of Nutrition, Harvard School of Public Health, Boston, MA, - - 2014
In children being taller is associated with higher blood pressure (BP), but few studies have divided height into its components: trunk and leg length. We examined the associations of total height, trunk length and leg length with systolic BP (SBP), diastolic BP (DBP) and pulse pressure (PP) at early childhood ...
de la Sierra A A Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, - - 2014
Sympathetic nervous system has an important role in resistant hypertension. Heart rate (HR) is a marker of sympathetic activity, but its association with resistant hypertension has not been assessed. We aimed to evaluate differences in HR values and variability between resistant and controlled patients and between true and white-coat resistant ...
Kobalava Zhanna Z Peoples' Friendship University of Russia, Moscow, Russian - - 2014
Abstract Objectives: The primary objective of this study was to establish the proportion of patients with stable angina and arterial hypertension on beta-blocker (BB) treatment reaching target resting heart rates (RHR) of 55-60 beats per min in clinical cardiology and general practice in Russia. Secondary objectives included the association between ...
Alsaleh Aseel A Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, - - 2014
Blood pressure is a heritable determinant of cardiovascular disease (CVD) risk. Recent genome-wide association studies have identified several single-nucleotide polymorphisms (SNPs) associated with blood pressure, including rs1378942 in the c-Src tyrosine kinase (CSK) gene. Fish oil supplementation provides inconsistent protection from CVD, which may reflect genetic variation. We investigated the ...
Rodrigues Sérgio Lamêgo SL Department of Physiological Sciences, Federal University of Espírito Santo, 29042-755 Vitória, Brazil. Electronic address: - - 2014
The purpose of this study was to investigate the influence of dietary potassium on the sodium effect on blood pressure (BP) in the general population and the adherence of current recommendations for sodium and potassium intake. An overnight (12-hour) urine sample was collected in a population-based study to investigate cardiovascular ...
Wei Fang-Fei FF Center for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Lab of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
Whether target organ damage is associated with blood pressure (BP) variability independent of level remains debated. We assessed these associations from 10-minute beat-to-beat, 24-hour ambulatory, and 7-day home BP recordings in 256 untreated subjects referred to a hypertension clinic. BP variability indices were variability independent of the mean, maximum-minimum difference, ...
Shouk Reem R Department of Biology, Faculty of Science, United Arab Emirates University, Al-Ain, United Arab - - 2014
Cardiovascular disease remains the leading cause of death worldwide with hypertension being a major contributing factor to cardiovascular disease-associated mortality. On a population level, non-pharmacological approaches, such as alternative/complementary medicine, including phytochemicals, have the potential to ameliorate cardiovascular risk factors, including high blood pressure. Several epidemiological studies suggest an antihypertensive ...
Stoner Lee L School of Sport and Exercise, Massey University, Wellington, New - - 2014
Pulse wave analysis (PWA) has emerged as a noninvasive, valid, reliable, and widely used technique to investigate central blood pressures and systemic arterial wave reflection (augmentation index). The gold-standard technique is tonometry, but this technique can be challenging, especially when used on children. The purpose of this study was to ...
Salazar Martin R MR Hospital Universitario San Martín, La Plata, Buenos Aires, - - 2014
The significance in terms of the cardiovascular outcome of different patterns of blood pressure (BP) response to community-based activities has not been previously studied. The aim of our study was to evaluate the relationship between changes of BP observed during a community-based program and long-term rate of cardiovascular disease (CVD) ...
Colussi Gianluca G Clinica Medica, Hypertension Unit, Department of Experimental and Clinical Medical Science, University of Udine, Udine, - - 2014
Studies on fish oil effects on ambulatory blood pressure (ABP) are inconclusive. We evaluated fish effects on fatty acid composition of red blood cell (RBC) membrane and ABP values and tested the hypothesis that the starting membrane fatty acid composition affects the ability to incorporate additional polyunsaturated fatty acids (PUFA) ...
Rosenwasser Rebecca F RF Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA. Electronic address: - - 2014
Elevated central systolic blood pressure (BP) increases the risk of cardiovascular events and appears superior to peripheral BP for long term risk prediction. The objective of this study was to identify demographic and clinical factors associated with central pressures in patients with uncomplicated hypertension. We prospectively examined peripheral BP, central ...
Lim Wai-Yee WY aSaw Swee Hock School of Public Health, National University of Singapore and National University Health System bKK Women's and Children's Hospital cYong Loo Lin School of Medicine, National University of Singapore and National University Health System dDepartment of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System eDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System fSingapore Institute for Clinical Sciences, Agency for Science and Technology Research (A'STAR) gMedicine Dean's Office, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore hMedical Research Council Lifecourse Epidemiology Unit, University of Southampton iNIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK jLiggins Institute, University of Auckland, Auckland, New Zealand *Seang-Mei Saw and An Pan contributed equally to the writing of this - - 2014
Greater maternal adiposity is a potentially modifiable risk factor for elevated blood pressure during pregnancy; however, the association has been little studied in Asian populations, and no study has evaluated potential differences in the adiposity-blood pressure relation between ethnic groups or interaction with gestational diabetes. We performed a cross-sectional evaluation ...
Arbique Debbie D UT Southwestern Medical Center at Dallas, Internal Medicine, Cardiology Division: Hypertension Section, Dallas, - - 2014
The burden of orthostatic hypotension (OH) on public health is a universally recognized enigmatic clinical condition that is associated with significant increases on morbidity and mortality rates, and can take a major toll on one's quality of life. Orthostatic hypotension is predictive of vascular deaths from acute myocardial infarction, strokes ...
Hänninen M-Ra MR Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, - - 2014
The association between masked hypertension and metabolic syndrome (MS) or insulin resistance is unclear. We investigated an untreated nationwide population sample (n=1582, age 44-74 years). Duplicate office blood pressure (BP) measurements were taken on one visit and duplicate morning and evening home measurements were taken for 7 days. Masked hypertension ...
Yücel Kamile K Center of Blood Konya Education and Research Hospital; Konya-Turkey. - - 2014
Masked hypertension is a clinical condition, the importance of which is agreed in recent years and which is characterized by increased cardiovascular mortality and morbidity and is thought to be important endothelial dysfunction in the pathophysiology. Plasma total homocysteine levels are accepted as a major independent biomarker for endothelial dysfunction ...
Flack John M JM Division of Translational Research and Clinical Epidemiology, Department of Medicine, Wayne State University, Detroit, MI, USA, - - 2014
African Americans have a higher burden of hypertension, more severe blood pressure (BP) elevations, more concurrent risk-enhancing co-morbidities (e.g., diabetes), sub-clinical vascular injury at lower non-hypertensive BP levels, lower BP control rates, and significantly greater risk for adverse pressure-related clinical complications (e.g., stroke, heart failure) than whites. Randomized prospective data ...
Hart E C J EC School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom; - - 2014
Sex and age have important influences on sympathetic neural control of blood pressure in humans. Young women are relatively protected against risk of hypertension due to greater peripheral vasodilator influences compared with young men and older people. This protective effect is lost at menopause. Older men and women have higher ...
Anderson James W JW Professor Emeritus, Medicine and Clinical Nutrition, University of Kentucky, Lexington, KY. - - 2014
Objective: To compare effects of raisin snacks with conventional snacks on glycemia and cardiovascular risk factors. Materials and Methods: A 12-week, randomized, controlled trial compared 3-times-a-day consumption of raisins with intake of processed snacks on glycemia and cardiovascular risk factors. Men and women were randomized to snacks (n = 15) ...
Streby Henry M HM Minnesota Cooperative Fish and Wildlife Research Unit, Department of Fisheries, Wildlife and Conservation Biology, University of Minnesota, , 200 Hodson Hall, St Paul, MN 55108, USA, US Geological Survey, Minnesota Cooperative Fish and Wildlife Research Unit, University of Minnesota, , 200 Hodson Hall, St Paul, MN 55108, USA, Department of Environmental Science Policy and Management, University of California, Berkeley, , 130 Mulford Hall, Berkeley, CA 94720, - - 2014
When opposing evolutionary selection pressures act on a behavioural trait, the result is often stabilizing selection for an intermediate optimal phenotype, with deviations from the predicted optimum attributed to tracking a moving target, development of behavioural syndromes or shifts in riskiness over an individual's lifetime. We investigated nest-site choice by ...
Dolezsar Cynthia M CM Department of Psychology, Concordia - - 2014
Objective: Discrimination is posited to underlie racial disparities in hypertension. Extant literature suggests a possible association between racial discrimination and blood pressure, although inconsistent findings have been reported. The aim of this comprehensive systematic review was to quantitatively evaluate the association between perceived racial discrimination with hypertensive status and systolic, ...
Murai Shunsuke S Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Nagoya, - - 2014
Kidney function and cardiovascular disease are closely connected and albuminuria is a proven marker of cardiovascular risk. The present study investigated the prevalence and characteristics of albuminuria in patients with hypertension. Outpatients with essential hypertension under medical treatment were enrolled in this study (n = 350, 70.0 ± 11.4 years ...
Asayama Kei K Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium ; Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, - - 2014
The Global Burden of Diseases Study 2010 reported that hypertension is worldwide the leading risk factor for cardiovascular disease, causing 9.4 million deaths annually. We examined to what extent self-measurement of home blood pressure (HBP) refines risk stratification across increasing categories of conventional blood pressure (CBP). This meta-analysis included 5,008 ...
Nascimento Dahan da Cunha Dda C Postgraduate Program in Physical Education, Catholic University of Brasilia, Brasilia, Brazil ; Department of Physical Education, University Center Euro American University Center, Brasilia, Brazil ; Strength Training and Health Research Group (GEPEEFS), Brasilia, - - 2014
Hypertension is the most prevalent modifiable risk factor with a high prevalence among older adults. Exercise is a nonpharmacological treatment shown to benefit all patients with hypertension. This study examined the effects of a 14-week moderate intensity resistance training program (RT) on the maintenance of blood pressure and hand grip ...
Xiao Wenkai W Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, - - 2014
Elevated plasma total homocysteine (tHcy) acts synergistically with hypertension to exert a multiplicative effect on cardiovascular diseases risk. The aim of this study was to determine the relationship between tHcy concentration and blood pressure, and to evaluate the role of plasma tHcy in arterial stiffness and wave reflection in hypertension. ...
Selvarajah Viknesh V Clinical Pharmacology Unit, Department of Medicine, University of Cambridge, Cambridge, United Kingdom ; Department of Nephrology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United - - 2014
Systolic blood pressure variability is an independent risk factor for mortality and cardiovascular events. Standard measures of blood pressure predict outcome poorly in haemodialysis patients. We investigated whether systolic blood pressure variability was associated with mortality in incident haemodialysis patients. We performed a longitudinal observational study of patients commencing haemodialysis ...
Sun Zhaoqing Z Division of Cardiology, Shengjing Hospital of China Medical University, Shenyang, P.R. - - 2014
This study was conducted to examine the differences in the incidence of hypertension and associated risk factors between Mongolian and Han populations in northeast China. A population-based sample of 4753 Mongolian subjects and 20,247 Han subjects aged ≥35 years and free from hypertension at baseline were followed from 2004-2006 to ...
Petrella Robert J RJ Department of Family Medicine and Cardiology, Lawson Health Research Institute, University of Western Ontario, ON, - - 2014
The Canadian Hypertension Education Program (CHEP) has identified blood pressure (BP) control as a key target for an overall reduction in cardiovascular disease risk. The POWER survey (Physicians' Observational Work on Patient Education According to their Vascular Risk) used Framingham methodology to investigate the impact of an angiotensin-receptor-blocker-based regimen on ...
Slade Alexander N AN a University of Illinois at - - 2014
Dietary modification has been shown to substantially reduce blood pressure among people with hypertension. This article uses data from the 2007-2008 and 2009-2010 cross-sections of the National Health and Nutrition Examination Survey (NHANES) to examine the extent to which a hypertension diagnosis can influence individuals' dietary choices. Several models were ...
Geiger Sarah Dee SD Department of Public Health, Northern Illinois University, School of Nursing and Health Studies, DeKalb, - - 2014
Hypertension is a leading cause of cardiovascular disease worldwide. Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are perfluoroalkyl chemicals (PFCs) used in the manufacture of common consumer products and detected in the blood of the majority of Americans. Emerging biological data suggest that PFC exposure may have a role in ...
Liang J Q JQ Department of Cell Biology, Capital Medical University, Beijing, - - 2014
Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). We therefore investigated the association between a CYP4A11 polymorphism (rs9333025) with hypertension in the Mongolian and Han ethnic groups. We studied 514 Mongolians in a pastoral ...
Bonsa Feyie F Department of Internal Medicine, Jimma University, - - 2014
Hypertension is the leading cause of death in the world and is the commonest cause for outpatient visits to physicians. The objective of this study was to assess the prevalence of hypertension and its risk factors among adults in Bedele Town, South-west Ethiopia. A community-based cross-sectional survey was conducted by ...
Joyner JaNae - - 2014
This study evaluates patient inertia (PtInert) factors including hopelessness in African Americans participating in church cardiovascular screening programs in low income areas in Forsyth County, North Carolina. Patient inertia is defined as an inability to assume adequate hypertension self-management behaviors, leading to poorly controlled hypertension. Previous findings revealed hopelessness related ...
Satoh Michihiro M Department of Pharmacy, Tohoku University Hospital , Sendai , Japan - - 2014
Abstract Based on ambulatory blood pressure (BP) monitoring, the aldosterone-to-renin ratio (ARR) has been reported to be associated with a diminished nocturnal decline in BP, generally referred to as a "non-dipping" pattern. The objective of this cross-sectional study was to investigate the association between ARR and the non-dipping pattern based ...
Sakaki Minako M Division of Hypertension - - 2014
Abstract Although salt restriction is very important for the management of blood pressure (BP), it is difficult to maintain low salt intake in hypertensive patients. The purpose of the present study is to investigate comparatively the characteristics of hypertensive patients with good or poor compliance to long-term salt restriction. Subjects ...
Qvist Ina I Department of Medicine, Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, - - 2014
In general, it is assumed that patient education, by increasing knowledge, may change behavior and lifestyle and promote health. In this context, it is a surprise that knowledge and awareness about blood pressure and hypertension among elderly people is poor. We hypothesized that knowledge about blood pressure and hypertension would ...
Isobe Takehito T Research Division, Chugai Pharmaceutical Co., - - 2014
Anti-angiogenic drugs that target Vascular Endothelial Growth Factor (VEGF) signaling pathways caused hypertension as an adverse effect in clinical studies. Since the hypertension may limit the benefit provided for patients, the demand for non-clinical research that predicts the clinical risk of the hypertension has risen greatly. To clarify whether non-clinical ...
Therrien J F - - 2014
Predation has been suggested to be especially important in simple food webs and less productive ecosystems such as the arctic tundra, but very few data are available to evaluate this hypothesis. We examined the hypothesis that avian predators could drive the population dynamics of two cyclic lemming species in the ...
Clark Cari Jo CJ Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, United States of America; Program in Health Disparities Research, University of Minnesota, Minneapolis, Minnesota, United States of - - 2014
Intimate partner violence has adverse health consequences, but little is known about its association with hypertension. This study investigates sex differences in the relationship between intimate partner violence and blood pressure outcomes. Data included 9,699 participants from waves 3 (2001-02) and 4 (2008-09) of the National Longitudinal Study of Adolescent ...
Liang Xiaohua X Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital, Chongqing Medical University, Chongqing, People's Republic of China; Centers for Disease Control and Prevention of Jiulongpo District, Chongqing, People's Republic of - - 2014
Non-communicable diseases are leading causes of disease burden in middle income countries. Little evidence exists to determine if the primary healthcare system can effectively manage non-communicable diseases. The purpose of this study was to examine the effectiveness of hypertension and diabetes management by the primary healthcare system. We used individual ...
Ng Khai P KP Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, United - - 2014
Arterial stiffness is increased in patients with CKD and is a powerful predictor of cardiovascular morbidity and mortality. Use of the xanthine oxidase inhibitor allopurinol has been shown to improve endothelial function, reduce left ventricular hypertrophy and possibly improve cardiovascular outcome. We explored the relationship between use of allopurinol and ...
Car Halina H Zakład Farmakologii Doświadczalnej, Uniwersytet Medyczny w - - 2014
Whey is a rich natural source of peptides and amino acids. It has been reported in numerous studies that biological active peptides isolated from cow's milk whey may affect blood pressure regulation. Studies on animals and humans have shown that α-lactalbumin and β-lactoglobulin obtained from enzymatically hydrolysed whey inhibit angiotensin ...
Ghosh Rajeshwary R 0000-0002-6576-4242 Sinha Institute of Medical Science and Technology, 288 Kendua Main Road, Garia 700 084, - - 2014
The effect of dermcidin isoform 2 (dermcidin), an environmentally induced stress protein, was investigated on the genesis of diabetes mellitus and hypertension, the two major atherosclerotic risk factors. The role of dermcidin as an atherosclerotic risk factor related to the impaired systemic insulin level was investigated. Dermcidin was prepared by ...
Kimura Shin-Ichiro S Department of Pharmacy Practice and Science, School of Pharmaceutical Sciences, University of - - 2014
Multiple regression analysis (MRA) and principal component analysis (PCA) have been used in the present study to examine the relationships between the operational conditions of a unique multi-functional rotor processor, material attributes such as water content during granulation, and a series of associated micromeritics, including the flowability, granule mean size ...
Panhwar Abdul Haleem - - 2014
The abnormal metabolism of metal ions plays an important role in health and disease conditions, and studies about them have been attracting significant interest. The aim of our study was to assess the essential minerals (calcium (Ca), magnesium (Mg), potassium (K), and sodium (Na)) in biological samples (scalp hair, blood, ...
Head Geoffrey A GA Baker IDI Heart and Diabetes Institute, Melbourne and Department of Cardiovascular Medicine, Alfred Hospital, Melbourne, - - 2014
We determined clinical predictors of the rate of rise (RoR) in blood pressure in the morning as well as a novel measure of the power of the BP surge (BPpower) derived from ambulatory blood pressure recordings. BPpower and RoR were calculated from 409 ambulatory blood pressure (ABP) recordings from subjects ...
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