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Huntington-Moskos Luz L College of Nursing, Clean Indoor Air Partnership, University of Kentucky, 751 Rose Street, 447 College of Nursing Building, Lexington, KY, 40536-0232, USA, - - 2014
The pathogenesis of hypertension begins in youth. An estimated 4 % of US adolescents have diagnosed hypertension and 17 % have elevated blood pressures, predisposing them to hypertension and cardiovascular disease (CVD) later in life. There is limited research on the clustering of CVD risk factors such as tobacco exposure and weight ...
Welsh Tomas J - - 2014
Hypertension is very common in older people and a number of trials of antihypertensives have demonstrated benefit from treatment in even the oldest old. However, people with dementia were significantly under-represented in these studies and as a population are more likely to be physically frail, to suffer orthostatic hypotension and ...
Malik Aaqib Habib AH Department of Internal and Preventive Medicine, Griffin Hospital, Derby, Connecticut; Yale-Griffin Prevention Research Center, Derby, Connecticut. Electronic address: - - 2014
The impact of sugar-sweetened beverages (SSBs) on blood pressure (BP) has been debated, with some evidence suggesting that their increased intake is related to higher risk of developing hypertension. We conducted a systematic review exploring the relation between consumption of SSB and BP. A comprehensive search in 5 electronic databases ...
Zuo Xiao-Cong XC Center of Clinical Pharmacology and Pharmacy Department, The Third Xiangya Hospital, Central South - - 2014
Summary: The effects of genetic polymorphisms of ABCB1 C3435T, POR*28, CYP3A4*1G and CYP3A5*3 variants and gender relating to metabolism on the exposure and response of amlodipine in Chinese hypertensive patients were determined. Population pharmacokinetic analyses were performed on data which were collected prospectively from 60 Chinese patients with mild to ...
Agarwal Rajiv R Indiana University School of Medicine and Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, Ind., - - 2014
To test the hypothesis that thiazide-type diuretics effectively lower blood pressure (BP) in moderate to advanced chronic kidney disease (CKD; estimated GFR 20-45 ml/min/ 1.73 m(2)), after confirming poorly controlled hypertension with 24-hour ambulatory BP monitoring, chlorthalidone was added to existing medications in a dose of 25 mg/day, and the ...
Xu Jianwei - - 2014
High levels of dietary sodium are associated with raised blood pressure and adverse cardiovascular health. To determine baseline salt intake, we investigated the average dietary salt intake from 24-hour urinary sodium excretion with a small sample of Yantai adults in the Shandong province of China. One hundred ninety one adults ...
Ushigome E E Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, - - 2014
Recent studies have shown that variability in home blood pressure has an important role in the progression of organ damage. The objective of this study was to investigate the factors that affect variability in home blood pressure in patients with type 2 diabetes. We assessed the relationship between home blood ...
Hermida R C RC Bioengineering and Chronobiology Laboratories, Atlantic Research Center for Information and Communication Technologies, University of Vigo, E.I. Telecomunicación, Campus Universitario, Vigo, - - 2014
Diagnosis of hypertension and clinical decisions regarding its treatment are typically based upon daytime clinic blood pressure (BP) measurements, occasionally supplemented by wake-time patient self-assessment. Yet, correlation between BP level and target organ damage, cardiovascular disease (CVD) risk, and long-term prognosis is higher for ambulatory BP monitoring (ABPM) measurements. Numerous ...
Kris-Etherton Penny M PM Department of Nutritional Sciences, Pennsylvania State University, University Park, - - 2014
Given the pressing need to reduce cardiovascular disease (CVD) morbidity and mortality, there has been a focus on optimizing dietary patterns to reduce the many contributing risk factors. Over the past 2 decades, many studies have been conducted that have evaluated the effects of walnut consumption on CVD risk factors. ...
Causland Finnian R Mc FR aRenal Division, Department of Medicine, Brigham and Women's Hospital bHarvard Medical School cDepartment of Medicine, Brigham and Women's Hospital dDepartment of Nutrition, Harvard School of Public Health eChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, - - 2014
Blood pressure normally declines during the night ('dipping'); a blunted nocturnal decline is an important cardiovascular risk factor. Marriage may be associated with lower ambulatory blood pressure, although this may be confounded by socio-economic and dietary factors. We examined the association of marital status with nocturnal dipping and night-time SBP ...
Gijón-Conde Teresa T Centro de Salud Universitario Cerro del Aire, Dirección Asistencial Noroeste, Majadahonda, Madrid, Spain; Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid/IdiPaz, CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. Electronic address: - - 2014
The prevalence of resistant hypertension has recently been reported, but there are no studies on its demography. This study aimed to examine the demography and clinical characteristics of resistant hypertension in a large sample of primary care patients. A cross-sectional study was performed of all computerized medical records of hypertensive ...
He Jiang J Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China2Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana3Department of Medicine, Tulane - - 2014
Although the benefit of reducing blood pressure for primary and secondary prevention of stroke has been established, the effect of antihypertensive treatment in patients with acute ischemic stroke is uncertain. To evaluate whether immediate blood pressure reduction in patients with acute ischemic stroke would reduce death and major disability at ...
James Paul A PA University of Iowa, Iowa - - 2014
Hypertension is the most common condition seen in primary care and leads to myocardial infarction, stroke, renal failure, and death if not detected early and treated appropriately. Patients want to be assured that blood pressure (BP) treatment will reduce their disease burden, while clinicians want guidance on hypertension management using ...
Bays Harold H Louisville Metabolic and Atherosclerosis Research Center Inc. (L-MARC), Louisville, KY, USA, - - 2014
Lowering blood pressure (BP) in patients with high blood pressure reduces cardiovascular risk. Studies support health benefits when BP goals are achieved earlier in the course of treatment. Many patients require combination therapy to achieve BP goals; initial use of combination therapy may improve earlier BP goal attainment. This analysis ...
Sung Joo-Wook JW Division of Cardiology, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of - - 2014
An association has been described between high sensitivity C-reactive protein (hs-CRP) and cardiovascular disease (CVD) in some studies but not in others. This finding may be explained by a differential impact of inflammation according to the absence or presence of certain co-existing risk factors. Because hypertension may be an effect ...
Gijón-Conde Teresa T Centro de Salud Universitario Cerro del Aire, Dirección Asistencial Noroeste, Majadahonda, Madrid, España; Departamento de Medicina Preventiva y Salud Pública, Universidad Autónoma de Madrid/IdiPaz, CIBER de Epidemiología y Salud Pública (CIBEResp), Madrid, España. Electronic address: - - 2014
The prevalence of resistant hypertension has recently been reported, but there are no studies on its demography. This study aimed to examine the demography and clinical characteristics of resistant hypertension in a large sample of primary care patients. A cross-sectional study was performed of all computerized medical records of hypertensive ...
Park Chang G CG Department of Internal Medicine, Korea University College of Medicine , Seoul , - - 2014
Abstract Lipocalin families including lipocalin-2 and adipocyte fatty acid binding protein (A-FABP) were recently identified as novel adipokines to be associated with the cardiovascular risk variables of the metabolic syndrome. We evaluated the lipocalin-2 and A-FABP levels in 62 patients with essential hypertension (EHT) and 16 age-, gender- and body ...
Pandey Arti S AS Department of Biochemistry, Xxx Medical College Basic Sciences Block, Xxx, Xxx, - - 2014
Tobacco consumption is high amongst the people of Xxx. This study was carried out in 2011 in a rural community of Xxx, to compare pathological parameters associated with tobacco use in relation to nicotine metabolism between smokers, chewers, and a control group. A total of 216 volunteers provided blood and ...
Komori Takahiro T Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine , Shimotsuke, Tochigi , - - 2014
Abstract Background: Masked uncontrolled hypertension (MUH), defined as controlled office blood pressure (BP) but uncontrolled out-of-office BP in treated hypertensives, is a risk factor for cardiovascular disease. We tested the hypothesis that MUH is associated with a greater degree of diastolic dysfunction than controlled hypertension (CH) or uncontrolled hypertension (UH). ...
Banegas José R JR Department of Preventive Medicine and Public Health, Universidad Autónoma de Madrid/IdiPAZ - CIBER in Epidemiology and Public Health (CIBERESP), AvdaArzobispoMorcillo 2, 28029 Madrid, - - 2014
There are limited data on the quality of treated blood pressure (BP) control during normal daily life, and in particular, the prevalence of 'masked uncontrolled hypertension' (MUCH) in people with treated and seemingly well-controlled BP is unknown. This is important because masked hypertension in 'treatment naïve' patients is associated with ...
Aoqui Cristiane - - 2014
Metabolic syndrome (MetS) is associated with increased risk of cardiovascular disease (CVD). One important feature underlying the pathophysiology of many types of CVD is microvascular dysfunction. Although components of MetS are themselves CVD risk factors, the risk is increased when the syndrome is considered as one entity. We aimed to ...
Alsmadi Osama O Dasman Genome Centre, Dasman Diabetes Institute, - - 2014
Recent research illustrates the role of central melanocortin signaling and leptin in the regulation of arterial blood pressure in animal models. Unraveling the genetic basis of interactions between melanocortin and leptin in humans will provide new insight into the regulation of arterial pressure. Our study population consisted of 332 Kuwaiti ...
Spinasse Lizania Borges LB Laboratory of Molecular Biology Applied to Mycobacteria - Oswaldo Cruz Institute - Fiocruz, Av. Brazil 4365, CEP: 21040-360, Manguinhos, Rio de Janeiro, - - 2014
Aim: Hydralazine, a vasodilator used in resistant hypertension (RH) treatment is metabolized by an acetylation reaction mediated by N-acetyltransferase 2, the activity of which depends on NAT2 polymorphisms. Our aim was to evaluate whether different acetylation phenotypes influenced the antihypertensive effect of hydralazine in patients with RH. Patients & methods: ...
Chaturvedi Swasti S Department of Paediatrics, Christian Medical College, Ida Scudder Road, Vellore, Tamil Nadu, India, - - 2014
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence of end organ damage and are at risk of ...
Elperin Dina T DT Kaiser Permanente Woodland Hills Medical Center, Woodland Hills, - - 2014
Hypertension is the most common primary diagnosis in the United States. Risks for long-term consequences such as myocardial infarction, heart failure, stroke, and kidney disease continue to significantly increase as long as hypertension remains uncontrolled. This retrospective cohort study of 661,075 patients identified with uncontrolled hypertension, defined as systolic blood ...
Senan Mahavir M National Institute of Govt, Kolkata, India; Yerevan State Medical University after M. Heratsi, - - 2014
The aim of the article was to study the relation between socioeconomic factors and mortality from CVS diseases. The study was performed among 346 native Indians (260 males and 86 females), aged 41-54 years and employed by the Civil Service. The study was carried out during 7 years. At 24 ...
Ringoir L L Department of Medical and Clinical Psychology, Centre of Research on Psychology in Somatic Diseases (CoRPS), Tilburg University, PO Box: 90153, 5000 LE, Tilburg, the - - 2014
Recent guidelines on cardiovascular disease prevention advocate the importance of psychological risk factors, as they contribute to the risk of developing cardiovascular disease. However, most previous research on psychological distress and cardiovascular factors has focused on selected populations with cardiovascular disease. The primary aim was to determine the prevalence of ...
Ko Seung-Hyun SH Division of Endocrinology and Metabolism, Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, - - 2014
We investigated the prevalence, awareness, treatment, and control rate of hypertension in Korean adults with diabetes using nationally representative data. Using data of 5,105 adults from the fifth Korea National Health and Nutrition Examination Survey in 2011 (4,389 nondiabetes mellitus [non-DM]), 242 newly diagnosed with DM (new-DM), and 474 previously ...
Onakpoya I I Department of Primary Care Health Sciences, University of Oxford, United Kingdom. Electronic address: - - 2014
Many different dietary supplements are currently marketed for the management of hypertension, but the evidence for effectiveness is mixed. The aim of this systematic review was to evaluate the evidence for or against the effectiveness of green tea (Camellia sinensis) on blood pressure and lipid parameters. Electronic searches were conducted ...
Hoshide Satoshi S Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, - - 2014
Several guidelines recommend that home blood pressure (HBP) be measured both in the morning and in the evening. However, there have been fewer reports about the clinical significance of morning HBP than about the clinical significance of evening HBP. Our study included 4,310 patients recruited for the Japan Morning Surge ...
Cheng Hao-Min HM Department of Medical Education, Taipei Veterans General Hospital, Taipei, - - 2014
Oscillometric central blood pressure (CBP) monitors have emerged as a new technology for blood pressure (BP) measurements. With a newly proposed diagnostic threshold for CBP, we investigated the diagnostic performance of a novel CBP monitor. We recruited a consecutive series of 138 subjects (aged 30-93 years) without previous use of ...
Aribisala Benjamin S BS Division of Neuroimaging Sciences, Brain Research Imaging - - 2014
White matter hyperintensities (WMH) are associated with hypertension. We examined interactions among blood pressure (BP), internal carotid artery (ICA) flow velocity parameters, and WMH. We obtained BP measurements from 694 community-dwelling subjects at mean ages 69.6 (±0.8) years and again at 72.6 (±0.7) years, plus brain MRI and ICA ultrasound ...
Lopes Liane M LM Laboratory of Neuromechanics, Center for Health Sciences, Federal University of Pampa, Uruguaiana, RS, - - 2014
Previous studies suggested that skin stimulation by using medical tape glued to the skin over the Achilles tendon can improve postural control in young adults. Such strategy can be valuable if helping to improve postural control in the elderly. Here we tested the effects of skin stimulation on the postural ...
Frontoni S S Department of Systems Medicine, University of Rome Tor Vergata - AFAR, Fatebenefratelli Hospital, Rome, Italy. Electronic address: - - 2014
Type 2 diabetes mellitus (T2DM) and essential hypertension are often associated, and retrospective data analyses suggest an association between lower blood pressure (BP) values and lower cardiovascular (CV) risk in patients with T2DM. However, the most recent intervention trials fail to demonstrate a further CV risk reduction, for BP levels ...
Fonseca Vivian A VA Tulane University, New Orleans, LA, USA. Electronic address: - - 2014
To quantify the effect of liraglutide on systolic blood pressure (SBP) and pulse in patients with type 2 diabetes (T2D), and assess the influence of covariates on observed SBP reductions. A patient-level pooled analysis of six phase 3, randomized trials was conducted. The analysis included 2792 randomized patients. In the ...
Annweiler Cédric C Department of Geriatric Medicine, Angers University Hospital; UPRES EA4638, University of Angers, UNAM, France; Robarts Research Institute, the University of Western Ontario, London, ON, - - 2014
Orthostatic hypotension, a condition that mostly affects 'oldest-old' (i.e. ≥80 years) adults, is primarily explained by age-related dysfunction of blood pressure control. Vitamin D may contribute to blood pressure control. The aim of this study was to determine whether vitamin D deficiency is associated with orthostatic hypotension in oldest-old adults. ...
Jaleta Gari Negeri - - 2014
Left ventricular hypertrophy (LVH) is an independent cardiovascular risk factor in patients with essential hypertension. The main objective of this study was to assess the echocardiographic prevalence of left ventricular hypertrophy in patients with hypertension, its risk factors and effect of antihypertensive drugs on its prevalence. A hospital based cross ...
Salles Gil F GF Internal Medicine Department, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, - - 2014
A blunted nocturnal blood pressure (BP) fall is a marker of worse cardiovascular outcomes, and autonomic imbalance may be involved. The objective was to evaluate the associations between the nocturnal BP fall and heart rate variability (HRV) parameters in resistant hypertension. In a cross-sectional analysis, 424 resistant hypertensive patients performed ...
Omboni Stefano S Italian Institute of Telemedicine, Via Colombera 29, 21048, Solbiate Arno (Varese), Italy, - - 2014
Hypertension is a frequent condition among individuals over 65 years of age worldwide and is one of the most important risk factors for cardiovascular (CV) disease. Effective drug treatment of elderly hypertensives is usually associated with a marked reduction in CV morbidity and mortality. Among the different classes of antihypertensive agents, ...
Takase H H Department of Internal Medicine, Enshu Hospital, Hamamatsu, - - 2014
We tested the hypothesis that uric acid levels predict new-onset hypertension in the Japanese general population. Normotensive individuals who visited our hospital for a yearly health checkup (n=8157, men=61.0% and age=50.7±12.2 years) were enrolled in the present study. After baseline evaluation, participants were followed up for a median of 48.3 ...
Duboz P P UMR 7268 ADèS, Aix-Marseille Université/EFS/CNRS, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, Marseille, - - 2014
The prediction of risk profile trends associated with non-communicable diseases in developing countries is among the greatest global health challenges. The aim of this study is to estimate prevalence, awareness, treatment and control of hypertension in Dakar (Senegal). This study was carried out between January and June 2009 on a ...
Bardell E West D EW School of Veterinary Science, Leahurst Campus, University of Liverpool, Neston, CH64 - - 2014
A prospective study to evaluate agreement and precision of a new point-of-care portable analyser, the EPOC analyser, compared with the i-STAT analyser in canine blood. Blood samples (68 venous and 32 arterial) were obtained from 63 client-owned dogs for clinical reasons and surplus blood was used to analyse agreement between ...
Gür Mustafa M Department of Cardiology, Adana Numune Training and Research Hospital , Adana , Turkey - - 2014
Abstract Even a slight decrease in the glomerular filtration rate (GFR) is an independent risk factor for cardiovascular disease. Arterial stiffness, left ventricular hypertrophy and N-terminal pro-brain natriuretic peptide (NT-proBNP) are independent risk factors for cardiovascular disease, which are particularly common in end-stage renal disease. We aimed to evaluate the ...
Angell Sonia Y SY At the time of the study, Sonia Y. Angell, Stella Yi, Christine J. Curtis, and Lynn D. Silver were with the Bureau of Chronic Disease Prevention; Donna Eisenhower, Bonnie D. Kerker, and Katherine Bartley were with the Bureau of Epidemiology Services; and Thomas A. Farley was with the New York City Department of Health and Mental Hygiene, New York, - - 2014
Objectives. We estimated sodium intake, which is associated with elevated blood pressure, a major risk factor for cardiovascular disease, and assessed its association with related variables among New York City adults. Methods. In 2010 we conducted a cross-sectional, population-based survey of 1656 adults, the Heart Follow-Up Study, that collected self-reported ...
Rifkin Dena E DE Division of Nephrology, Department of Medicine, University of California-San Diego, San Diego, - - 2014
Although variations in plasma renin activity (PRA) and aldosterone have been examined in whites and blacks, the association of these hormones with blood pressure in multiethnic populations has not been described. We measured PRA and aldosterone in 1,021 participants in the Multi-Ethnic Study of Atherosclerosis not taking antihypertensives and examined ...
Lambert Elisabeth A EA Human Neurotransmitters Laboratory, Baker IDI Heart & Diabetes Institute, Melbourne, Victoria, - - 2014
An exaggerated morning surge in blood pressure (BP) closely relates to target organ damage and cardiovascular risk, but whether the causative mechanism involves greater reactivity of the sympathetic nervous system (SNS) is unknown. We determined whether the response of the SNS to a cold pressor test predicted the BP morning ...
Dang Stefan S Research Group Bioinformatics, Center of Medical Biotechnology and Faculty of Biology, University of Duisburg-Essen, Essen, 45117, - - 2014
HIV-1 evolves strongly and undergoes geographic differentiation as it spreads in diverse host populations around the world. For instance, distinct genomic backgrounds can be observed between the pandemic subtype B, prevalent in Europe and North-America, and its offspring clade B' in East Asia. Here we ask whether this differentiation affects ...
Stergiou George S GS Hypertension Center, Third University Department of Medicine, Sotiria Hospital, Athens, - - 2014
Home blood pressure monitoring is useful in detecting white-coat and masked hypertension and is recommended for patients with suspected or treated hypertension. The prognostic significance of white-coat and masked hypertension detected by home measurement was investigated in 6458 participants from 5 populations enrolled in the International Database of HOme blood ...
Chen Jinfeng J Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, 210029, - - 2014
Fibrillin-1 (FBN1) was reported to have impact on the physiological arterial stiffness and vascular remodeling with hypertension of recent years. In the previous study we reported the association of four functional single nucleotide polymorphisms (SNPs) of FBN1 gene and hypertension. Here, we further investigate the association of four tagging SNPs ...
Shimoji Keigo K Department of Radiology, National Center of Neurology and Psychiatry Hospital, Kodaira, Tokyo, 187-8551, Japan, - - 2014
Hypertension is associated with substantial morbidity in Japan. The aim of this work was to evaluate whether hypertension is associated with white matter microstructural changes by using diffusional kurtosis imaging (DKI). We explored the regional patterns of white matter alteration in 15 hypertensive middle-aged male participants and 11 normotensive controls ...
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