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Hobbs D A DA 1] Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading, Berkshire, UK [2] Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, Whiteknights, Reading, Berkshire, - - 2014
Our objective was to investigate whether the presence of Glu298Asp polymorphism in the endothelial NO synthase (eNOS) gene differentially affects the postprandial blood pressure response to dietary nitrate-rich beetroot bread. A randomised, single-blind, controlled, crossover acute pilot study was performed in 14 healthy men (mean age: 34±9 years) who were ...
Patel Anushka A The George Institute for Global Health, University of Sydney, - - 2014
Most individuals at high cardiovascular disease (CVD) risk worldwide do not receive any or optimal preventive drugs. We aimed to determine whether fixed dose combinations of generic drugs ('polypills') would promote use of such medications. We conducted a randomized, open-label trial involving 623 participants from Australian general practices. Participants had ...
Lammertyn Leandi L Hypertension in Africa Research Team (HART), North-West University (Potchefstroom Campus), Potchefstroom, South - - 2014
Hypertension is highly prevalent in black South Africans in which morbidity and mortality from stroke are on the increase. Elevated blood pressure and haemostatic markers can induce changes in blood rheology and endothelial function which could result in a procoagulant state that increases the risk for cerebrovascular disease. Information about ...
Afsar Baris B Konya Numune State Hospital, Department of Nephrology, Turkey. Electronic address: - - 2014
The current study aimed to investigate the relationship between morning blood pressure surge (MBPS), hemodynamic parameters, glycemic control and 24-h urinary sodium excretion (USE) in patients with type 2 diabetes mellitus (T2DM). MBPS and central hemodynamic parameters were assessed from ambulatory blood pressure measurements. In addition to routine biochemistry, 24h ...
Farias Serafin S Emergency Medicine, Baylor College of Medicine, Houston, TX. Electronic address: - - 2014
The effect profile of differing antihypertensive agents is well studied, but minimal data regarding the interaction between hemodynamic response and presenting blood pressure (BP) exist. Achievement of target BP is less likely in patients with higher initial BPs. This is a substudy of the multicenter safety and efficacy Evaluation of ...
Morley John E JE Divisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine, 1402 S. Grand Blvd., M238, St. Louis, MO, 63104, USA, - - 2014
Evidence for treatment of hypertension in older people is limited to placebo-controlled studies that reduced blood pressure in persons over 60 years who had systolic blood pressure >160 mmHg. Generally, physicians measure blood pressure poorly, failing to look for white coat or masked hypertension, orthostasis, postprandial hypotension, or pseudohypertension. There is evidence ...
Polonia Jorge J aFaculdade Medicina da Universidade do Porto, Porto, Portugal & Unidade Hipertensão, ULS Matosinhos bFaculdade Ciências Saúde, Universidade Fernando Pessoa & CHEDV, Epe, Feira cCHEDV, Epe, Feira dHospital Egas Moniz, Lisboa eSociedade Portuguesa de Hipertensão (Portuguese Society of Hypertension), - - 2014
To determine prevalence, awareness, treatment and control of hypertension and the 24-h sodium excretion (24h-UNa) in the Portuguese adult population and to examine their changes from a similar study done in 2003. A population-based cross-sectional survey conducted in 2011-2012. A multistage-stratified (by age and sex) sampling method was used to ...
Grübler Martin R MR Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Graz, Austria; Department of Cardiology, Medical University of Graz, Graz, - - 2014
High aldosterone levels are considered to play a key role in arterial hypertension. Data on the relationship between the aldosterone to active renin ratio (AARR), a quantity of aldosterone excess, and ambulatory blood pressure (BP) monitoring (ABPM) during the night are, however, sparse. Hypertensive patients were recruited from local outpatient ...
Diedler Jennifer - - 2014
Current guidelines for spontaneous intracerebral hemorrhage (ICH) recommend maintaining cerebral perfusion pressure (CPP) between 50-70 mmHg, depending on the state of autoregulation. We continuously assessed dynamic cerebral autoregulation and the possibility of determination of an optimal CPP (CPPopt) in ICH patients. Assocations between autoregulation, CPPopt and functional outcome were explored. ...
Kawasaki Isao I Department of Metabolism and Endocrinology, Osaka City General Hospital, Osaka, - - 2014
We investigated the change in the urine albumin-to-creatinine ratio (ACR) to examine the effect of sitagliptin on diabetic nephropathy. Sitagliptin at a dose of 50 mg was administered to 247 outpatients with type 2 diabetes. Data was collected on the patients' laboratory results (including the ACR), blood pressure, and body ...
Weinert Letícia S LS Graduate Program in Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, - - 2014
Vitamin D deficiency in pregnancy has been associated with an increased risk of preeclampsia. However, the association between serum vitamin D and blood pressure in pregnant women has been scarcely evaluated, particularly in women with a high risk of developing hypertensive disorders of pregnancy. We sought to evaluate the association ...
Arguelles William W Department of Psychology, University of Miami, United States. Electronic address: - - 2014
Data describing relationships between change in risk factors and coronary artery calcification (CAC) are lacking and could inform optimal cardiovascular disease prevention and treatment strategies. This study aimed to examine how change in traditional cardiometabolic risk factors related to change in CAC among individuals with detectable subclinical atherosclerosis. Latent growth ...
Song SuJin S Department of Food and Nutrition, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Republic of - - 2014
Dietary factors are not consistently associated with metabolic syndrome abnormalities. In this cross-sectional study, we hypothesized that distinct clustering patterns exist in metabolic syndrome abnormalities and that those patterns are differentially associated with dietary factors. To test this hypothesis, we examined distinct clustering patterns of metabolic syndrome abnormalities and their ...
Mori Hiromi H Department of Public Health, Ehime University Graduate School of Medicine, Ehime, - - 2014
Heart rate variability (HRV) is associated with blood pressure levels; however, very few studies have correlated HRV to lifestyle in the general population. We investigated 1418 men and 2040 women aged 40-74 years and measured the HRV indices in the time and frequency domains using a 5-min R-R interval recording. ...
Hecking Manfred M Department of Internal Medicine III-Nephrology, Medical University of Vienna, Vienna, - - 2014
Diffusive sodium removal has been recommended to control hypertension in hemodialysis patients. Recent evidence on hospitalizations and mortality, however, challenged the benefit of lower dialysate sodium prescriptions and ignited a debate in the dialysis community. We therefore studied the relationship between dialysate sodium and blood pressure over the longer term. ...
Yamaguchi Yoshitaka Y Department of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology, Yamagata University Faculty of Medicine, Yamagata, - - 2014
Recent epidemiological studies reported a relationship between 24-hour ambulatory blood pressure (ABP) variability and cardiovascular events. However, the impact of ABP variability on small vessel disease (SVD) progression or cognitive decline in the elderly has seldom been investigated in community-based longitudinal studies. Subjects (n = 210) underwent ABP monitoring, brain ...
Oliveras Anna A Hypertension Unit, Nephrology Department, Hospital Universitari del Mar, Barcelona, - - 2014
Although elevated urinary albumin excretion (UAE) is associated with cardiovascular prognosis and high blood pressure (BP), it is unknown whether differences in BP control could also exist between patients with different grades of UAE, even in the normal range. We sought to explore the association between different levels of UAE ...
Xu Hong H Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, - - 2014
Both increased albuminuria and reduced kidney function may predict blood pressure (BP) progression in the community, while they exacerbate each other's effects. We investigated associations and interactions between these two risk factors, BP changes and hypertension incidence in community-dwelling elderly men. Observational study from the Uppsala Longitudinal Study of Adult ...
Saerens Lien L Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Ghent, Belgium. Electronic address: - - 2014
The aim of this research was to use Raman spectroscopy for the in-line monitoring of the solid state of materials during pharmaceutical hot-melt extrusion in the die head of a 12mm (development scale) twin-screw extruder during formulation development. A full factorial (mixed) design was generated to determine the influence of ...
Asfar Pierre P The authors' affiliations are listed in the - - 2014
The Surviving Sepsis Campaign recommends targeting a mean arterial pressure of at least 65 mm Hg during initial resuscitation of patients with septic shock. However, whether this blood-pressure target is more or less effective than a higher target is unknown. In a multicenter, open-label trial, we randomly assigned 776 patients ...
Kiselev Vladimir D - - 2014
We collected and analyzed the density and permittivity of 57 nonpolar and dipolar molecular liquids at different temperatures (143 sets) and pressures (555 sets). No equation was found that could accurately predict the change to polar liquid permittivity by the change of its density in the range of the pressures ...
Piotrowicz Karolina - - 2014
This paper summarizes the evidence supporting the pharmacological treatment of hypertension in the elderly as well as some the remaining controversies. The world is becoming progressively older and with that, the prevalence of hypertension is increasing. A peculiar form of hypertension, most prevalent among the elderly, is isolated systolic hypertension ...
Ramos Rodrigo A RA Postgraduate Program of Rehabilitation Science, Centro Universitário Augusto Motta/UNISUAM, Rio de Janeiro, - - 2014
This study investigated the association between hemodynamic variables and the 6-minute walk distance (6MWD) in adults with and without hypertension and explored the role of hemodynamic variables as predictors of 6MWD. Patients undergoing antihypertensive medication therapy (n=41) and sex-matched healthy subjects (n=41) were evaluated for their clinical status and cardiovascular ...
Balijepalli Chakrapani C 1] Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany [2] Providence Health Care Research Institute, University of British Columbia, Vancouver, British Columbia, - - 2014
Contemporary epidemiological data on blood pressure readings, hypertension prevalence and control in unselected patient populations covering a broad age range are scarce. The aim here is to report the prevalence of high blood pressure and to identify factors associated with blood pressure control in a large German primary care sample. ...
Aydın Gökçen G Department of Surgery Nursing, Health School, Bozok University, Yozgat, - - 2014
This study was conducted to assess daily living activities, pressure sores and risk factors. This was a descriptive study. The study was conducted at a rehabilitation center with 188 individuals participating in the study. Data were collected with a questionnaire form, Activities of Daily Living Scale (ADLS), Instrumental Activities of ...
Basu Biswanath B Department of Pediatrics, NRS Medical College & Hospital, Kolkata, - - 2014
Prediction of mortality among newborns on mechanical ventilation is difficult. Our aim was to develop a scoring system for predicting mortality among such neonates. This multi centre prospective study was performed to develop and validate a scoring system among two equal cohorts of ventilated newborns in India. Mechanical ventilator was ...
Bromfield Samantha G SG University of Alabama at Birmingham, Birmingham, - - 2014
The authors examined trends in systolic blood pressure (SBP) and diastolic blood pressure (DBP) and the prevalence, awareness, treatment, and control of hypertension in 1988-1994 (n=1164), 1999-2004 (n=1,026), and 2005-2010 (n=1048) among US adults 80 years and older in serial National Health and Nutrition Examination Surveys. Hypertension was defined as SBP ...
Outdili Zaïneb Z aInstitute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne bUniversity Children's Hospital, Inselspital and University of Bern, Bern cService of Nephrology, Lausanne University Hospital, Lausanne, Switzerland dDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, - - 2014
The diagnosis of hypertension in children is difficult because of the multiple sex-, age-, and height-specific thresholds to define elevated blood pressure (BP). Blood pressure-to-height ratio (BPHR) has been proposed to facilitate the identification of elevated BP in children. We assessed the performance of BPHR at a single screening visit ...
Merino Jordi J Vascular Medicine and Metabolism Unit and Research Unit on Lipids and Atherosclerosis, Sant Joan University Hospital, IISPV, Rovira i Virgili University, 43201 Reus, Spain; Spanish Biomedical Research Network in Diabetes and Associated Metabolic Disorders (CIBERDEM), 08017 Barcelona, Spain. Electronic address: - - 2014
Dietary long-chain n-3 polyunsaturated fatty acids (LCn-3PUFA) improve endothelial function in medium-large-sized arteries, but effects on small peripheral arteries, responsible for most arterial resistance, are little known. We investigated the effects of increasing LCn-3PUFA intake with the usual diet on small artery reactive hyperemia index (saRHI). Within a clinical trial ...
Li Tiegang - - 2014
Scrub typhus is becoming the most common vector born disease in Guangzhou, southern China. In this study, we aimed to examine the effect of weather patterns on the incidence of Scrub typhus in the subtropical city of Guangzhou for the period 2006-2012, and assist public health prevention and control measures. ...
Bleho Barbara I BI Golder Associates Ltd, 102, 2535 - 3rd Avenue SE, Calgary, AB, T2A 7W5, - - 2014
Effects of grazing on grassland birds are generally thought to be indirect, through alteration of vegetation structure; however, livestock can also affect nest survival directly through trampling and other disturbances (e.g., livestock-induced abandonment). We extracted data on nest fates from 18 grazing studies conducted in Canada. We used these data ...
Mousa Moataz Bellah M - - 2014
High throughput spatial atomic layer deposition (ALD) often uses higher reactor pressure than typical batch processes, but the specific effects of pressure on species transport and reaction rates are not fully understood. For aluminum oxide (Al2O3) ALD, water or ozone can be used as oxygen sources, but how reaction pressure ...
Lamy Sébastien S aINSERM, UMR 1027, Maladies Chroniques, Pratiques de Soins et Facteurs Socio-économiques bUniversité Paul Sabatier, UMR 1027, Toulouse cCNRS, UMR 5525, Laboratoire TIMC-IMAG, Equipe Environnement et Prédiction de la Santé des Populations dUniversité Joseph Fourier, UMR 5525, Grenoble eCHRU Lille, Clinique de Santé Publique, Médecine du Travail et Pathologies Professionnelles fUniversité Lille 2, Lille gCNRS, UMR 5194, Laboratoire PACTE (Politiques Publiques, Action Publique, Territoires), hUniversité Joseph Fourier, UMR 5194, Grenoble, - - 2014
Many studies have supported the role of organizational work factors (OWFs) on the risk of cardiovascular diseases (CVDs) and CVD risk factors, including arterial hypertension. However, a little information is available concerning the role of collective stressors deriving from work organization on nurse's risk of hypertension. This study aimed to ...
Bots Michiel L ML Julius Center for Health Sciences and Primary - - 2014
Carotid intima-media thickness (CIMT) is a marker of cardiovascular risk. It is unclear whether measurement of mean common CIMT improves 10-year risk prediction of first-time myocardial infarction or stroke in individuals with elevated blood pressure. We performed an analysis among individuals with elevated blood pressure (ie, a systolic blood pressure ...
Teo Koon K KK Population Health Research Institute, McMaster-University-Hamilton Health Sciences, Hamilton, ON, - - 2014
We studied the unclear question whether blood pressure (BP) lowering reduces cardiovascular disease (CVD) in elderly individuals with systolic BP <160 mm Hg. We initiated a randomized placebo-controlled stratified 2 × 2 factorial clinical trial evaluating the effects of BP lowering in 11 000 elderly individuals with systolic blood pressure ...
Cuspidi Cesare C Department of Health Science, University of Milano-Bicocca, Milan, - - 2014
Data on the prognostic value of echocardiographic left ventricular (LV) hypertrophy (LVH) as defined by LV wall thickness rather than LV mass estimate are scarce and not univocal. Thus, we investigated the value of LV mass index, wall thickness, and relative wall thickness (RWT) in predicting cardiovascular events in the ...
van Dooren Miesje M Department of Neurology, Maastricht University Medical Centre, Maastricht, The - - 2014
Brain microbleeds (BMBs) are common in hypertensive patients and are associated with higher blood pressure (BP) levels. Little is known about risk factors for progression of BMBs, in particular the contribution of ambulatory BP levels. We aimed to determine BMB progression and the association with BP levels in a cohort ...
Terracciano Antonio A Florida State University College of Medicine (A.T., A.R.S.), Tallahassee, Florida; National Institute on Aging, National Institutes of Health (A.T., J.S., O.M., A.R.S., K.T., J.D., E.L., D.S.), Baltimore, Maryland; Istituto di Neurogenetica e Neurofarmacologia (M.M., M.G.P., F.C.), Consiglio Nazionale delle Ricerche, Cagliari, Italy; Hospital San Raffaele Pisana IRCCS (A.S.), Rome, Italy; and Unità Operativa Complessa Cardiologia (M.O.), Presidio Ospedaliero A. Businco, Cagliari, - - 2014
ObjectiveA nighttime dip in blood pressure is associated with decreased risk of cardiovascular morbidity and mortality. We examined whether personality traits predict nighttime dipping blood pressure.MethodsA community-based sample of 2848 adults from Sardinia (Italy) completed the Revised NEO Personality Inventory and 7 years later were examined with 24-hour ambulatory blood ...
Wada Naoki - - 2014
The baroreflex plays a key role in human blood pressure (BP) regulation. Its efferent limb consists of a vagal and a sympathetic component. The Valsalva maneuver is widely used to quantify vagal baroreflex function (vagal baroreflex sensitivity, BRS_vagal), but most studies have focused on the R-R interval response to BP ...
Matsui Kunihiko K Department of General Medicine, Yamaguchi University Hospital, Yamaguchi, - - 2014
The OlmeSartan Calcium Antagonists Randomized (OSCAR) study is a multicenter, prospective, randomized, open-label, blinded, end point study of elderly hypertensive Japanese patients that compared the efficacy of a high-dose angiotensin II receptor blocker (ARB) treatment to an ARB plus calcium channel blocker (CCB) combination. In this pre-specified subgroup analysis, we ...
Okada Masahiro M Department of Food and Dietetics, Hiroshima Bunka Gakuen Two-Year College, 3-5-1 Nagatsukanishi, Asaminami-ku, Hiroshima, 731-0136, Japan, - - 2014
Previous studies of autonomic nervous system responses before and after eating when controlling patient conditions and room temperature have provided inconsistent results. We hypothesized that several physiological parameters reflecting autonomic activity are affected by outdoor temperature before and after a meal. We measured the following physiological variables before and after ...
Kollias Anastasios A Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, University of Athens, Sotiria Hospital, Athens, - - 2014
White-coat hypertension is defined by elevated office and normal out-of-office blood pressure (home or ambulatory) in untreated subjects. This condition is common in clinical practice and requires appropriate work-up for detection and management. Many studies have examined the relationship between white-coat hypertension and cardiovascular risk but with marked heterogeneity in ...
Miller Paige E PE Center for Epidemiology, Biostatistics, and Computational Biology, Exponent, Inc, Chicago, - - 2014
Although a large body of literature has been devoted to examining the relationship between eicosapentaenoic and docosahexaenoic acids (EPA+DHA) and blood pressure, past systematic reviews have been hampered by narrow inclusion criteria and a limited scope of analytical subgroups. In addition, no meta-analysis to date has captured the substantial volume ...
Babisch Wolfgang W Department of Environmental Hygiene, Federal Environment Agency, Berlin, - - 2014
Studies on the association between traffic noise and cardiovascular diseases rarely considered air pollution as a covariate in the analyses. Isolated systolic hypertension has not yet been in the focus of epidemiological noise research. The association between traffic noise (road and rail) and the prevalence of hypertension was assessed in ...
Okusa Kensuke K GL Sciences Inc., Iruma, Saitama 358-0032, - - 2014
A high-density, polymeric C18 stationary phase (Inertsil ODS-P) or a polymeric C30 phase (Inertsil C30) provided improved resolution of the isomeric fatty acids (FAs), FA methyl esters (FAMEs), triacylglycerols (TAGs), and tocopherols with an increase in pressure of 20-70MPa in reversed-phase HPLC. With respect to isomeric C18 FAMEs with one ...
Mengistu Mekoya D - - 2014
Hypertension is the 3rd cause of death accounting for one in eight deaths worldwide. Hypertension was thought to be rare in Africa, but it is now recognized as one of the most important cerebrovascular diseases contributing to about 40% of these diseases in the continent.The aims of this study were ...
Tóth Kálmán K 1st Department of Medicine, University of Pécs, Medical School, Ifjúság St. 13, Pecs, 7624, Hungary, - - 2014
Our objective was to evaluate a triple-drug antihypertensive strategy for blood pressure control in patients with difficult-to-treat hypertension. The Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients (PIANIST) trial was an observational, 4-month, open-label study. A total of 4,731 patients at high or very high cardiovascular risk with hypertension that ...
Guinot P-G PG Anaesthesiology and Critical Care Department, Amiens University Hospital, Place Victor Pauchet, Amiens 80054, - - 2014
/st>The objective of this study was to determine whether assessment of stroke volume (SV) and measurement of exhaled end-tidal carbon dioxide $({\small{\rm E}}{^{\prime}_{{\rm C}{{\rm O}_2}}})$ during an end-expiratory occlusion (EEO) test can predict fluid responsiveness in the operating theatre. /st>Forty-two subjects monitored by oesophageal Doppler who required i.v. fluids during ...
Konno Satoshi S Preventive Medical Center and Division of Hypertension, Tohoku Rosai - - 2014
Objectives: The aim of this study was to investigate the association between skill underutilization, a psychological job stressor proposed in the NIOSH (National Institute for Occupational Safety and Health) job stress model, and the prevalence of hypertension. Methods: We studied sitting blood pressure and fasting blood laboratory parameters in 3,429 ...
Shema-Didi Lilach - - 2014
Atherosclerotic cardiovascular disease (CVD) is the most common cause of morbidity and mortality among hemodialysis (HD) patients. It has been attributed, among other causes, to hypertension and dyslipidemia. The aim of the present study was to investigate the effect of a year-long consumption of Pomegranate juice (PJ), on two traditional ...
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