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Bruera Sebastian S Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, - - 2014
Few studies have examined variation in vital signs in the last days of life. We determined the variation of vital signs in the final two weeks of life in patients with advanced cancer and examined their association with impending death in three days. In this prospective, longitudinal, observational study, we ...
Carson Valerie V Faculty of Physical Education and Recreation, University of Alberta, Edmonton, AB, Canada; Healthy Active Living and Obesity Research Group, CHEO Research Institute, Ottawa, ON, Canada. Electronic address: - - 2014
To examine the associations of total sedentary time and patterns of sedentary time with cardiometabolic biomarkers in a large representative sample of Canadian adults. The study is based on 4,935 adults aged 20-79 years, from the 2007/09 and 2009/11 Canadian Health Measures Survey. Total sedentary time, patterns of sedentary time ...
Inal Salih S Department of Nephrology, Faculty of Medicine, Gazi University, Ankara, Turkey, - - 2014
Chronic volume overload, hypertension and left ventricular hypertrophy are major risk factors contributing to the high mortality rate in peritoneal dialysis (PD) patients. In this study, we aimed to determine the impact of blood pressure measurements and volume status determined by bioelectrical impedance analysis (BIA) measurements over left ventricular hypertrophy ...
Song Y Y Department of Anaesthesiology and Pain Medicine - - 2014
/st>We studied respirophasic variation in carotid artery blood flow peak velocity (ΔVpeak-CA) measured by pulsed wave Doppler ultrasound as a predictor of fluid responsiveness in mechanically ventilated patients with coronary artery disease. /st>Forty patients undergoing elective coronary artery bypass surgery were enrolled. Subjects were classified as responders if stroke volume ...
Zhang Ya-Ping YP Department of Cardiology, Central South University, Changsha, China - - 2014
Background/Aims: Intensive blood pressure (BP) target decreases blood perfusion of kidneys that attenuates the benefits of BP treatment in elderly hypertensive individuals. The optimal BP goal for renal function in the hypertensive elderly has been unclear. We investigated the impact of BP on renal function to define the appropriate BP ...
Tsukinoki Rumi R Department of Public Health Nursing, Osaka Medical College, Takatsuki, Osaka, - - 2014
Blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) are risk factors for coronary artery disease (CAD) and ischemic stroke. However, the hazards of their coexistence are not fully understood in Asian populations. We investigated whether the relationship between BP and cardiovascular disease (CVD) outcomes are modified by LDL-C level in ...
Muxfeldt Elizabeth S ES Hypertension Program, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro, - - 2014
Obstructive sleep apnea (OSA) syndromes are strongly associated with resistant hypertension, although this has not been systematically examined. The aim of our study was to investigate the prevalence of OSA and its associated factors in a large cohort of resistant hypertensive patients. A cross-sectional analysis with 422 resistant hypertensive patients ...
Campbell Katrina L - - 2014
Dietary sodium restriction is a key management strategy in chronic kidney disease (CKD). Recent evidence has demonstrated short-term reduction in blood pressure (BP) and proteinuria with sodium restriction, however the effect on other cardiovascular-related risk factors requires investigation in CKD. The LowSALT CKD study involved 20 hypertensive Stage III-IV CKD ...
Rock Wasseem W Department of Internal Medicine D and Hypertension Unit, The Chaim Sheba Medical Center, Tel-Hashomer, - - 2014
Recent guidelines recommend a target clinic systolic blood pressure (BP) of <140 mm Hg. These recommendations are based on the relationship of office BP measurements and cardiovascular (CV) events. We evaluated the association between 24-hour ambulatory BP measurements (24H ABPM) and CV events in a selected population with intensive control of ...
Derosa Giuseppe G Department of Internal Medicine and Therapeutics, University of Pavia and Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy; Center for the Study of Endocrine-Metabolic Pathophysiology and Clinical Research, University of Pavia, Pavia, Italy. Electronic address: - - 2014
The aim of this study was to evaluate enalapril/lercanidipine combination effects on markers of cardiovascular risk stratification in hypertensive patients. A total of 359 patients were randomized to enalapril 20 mg, lercanidipine 10 mg, or enalapril/lercanidipine 20/10 mg fixed combination. We evaluated blood pressure (BP), fasting plasma glucose (FPG), lipid profile, lipoprotein(a) (Lp[a]), ...
Coutinho Thais T Department of Medicine, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, - - 2014
Arterial stiffness is associated with incident hypertension. We hypothesized that measures of arterial stiffness would predict increases in systolic (SBP), mean (MAP), and pulse pressure (PP) over time in treated hypertensives. Blood pressure (BP) was measured a mean of 8.5 ± 0.9 years apart in 414 non-Hispanic white hypertensives (mean age, 60 ± 8 years; 55% ...
Martínez-Orozco M J MJ 1] Miguel Martínez Community Pharmacy, Benimantell, Spain [2] Department of Clinical Medicine, Miguel Hernández University, San Juan de Alicante, - - 2014
Antiplatelet therapy (AT) is indicated in hypertensive patients with increased cardiovascular risk. The literature about the adequate or inadequate prescription of AT is scarce. We conducted a prospective descriptive study to quantify therapeutic inertia and non-guideline-recommended prescription (NGRP) of AT (aspirinor clopidogrel or both), and to assess associated factors, calculating ...
Coulson J M JM All Wales Therapeutics and Toxicology Centre, Cardiff and Vale University Health Board, Cardiff, - - 2014
Ambulatory blood pressure variability (ABPV) is a predictor of cardiovascular risk in hypertensives. Factors that contribute to ABPV are not well described. This pilot study aimed to investigate the relationship between ABPV and urine catecholamine metabolites in order to rationalise further therapeutic intervention in the management of hypertension. Twenty individuals ...
Ueda H H 0000000324017416 Department of Cardiology, Sumitomo Hospital, Osaka, - - 2014
Whether high-normal blood pressure (BP) is a predictor of new-onset electrocardiographic (ECG)-left ventricular hypertrophy (LVH) is not known. A total of 4112 subjects who underwent physical examinations were enrolled in this study. BP was measured on entry. Standard 12-lead ECG was recorded at initial evaluation and 3 years later. BP ...
Wang Jinwei J Renal Division, Department of Medicine, Peking University First Hospital, Beijing, - - 2014
Hypertension is one of the major risk factor for cardiovascular disease worldwide. The objective of this study was to investigate the prevalence, awareness, treatment, and control of hypertension in China. A multistage, stratified sampling method was used to obtain a representative sample of persons aged 18 years or older in ...
Rizos Christos V CV University of Ioannina, School of Medicine, Department of Internal Medicine , Ioannina , - - 2014
Blood pressure plays an important role in the development and progression of cardiovascular disease. Among hypertensive patients, those with African ancestry present with distinctive metabolic characteristics and cardiovascular profile. As a result, the need for individualized antihypertensive treatment strategy is of great importance. Lifestyle modifications as well as low sodium ...
Foulds Heather J A HJ aExperimental Medicine Program, Faculty of Medicine, University of British Columbia bCardiovascular Physiology and Rehabilitation Laboratory, Physical Activity Promotion and Chronic Disease Prevention Unit, University of British Columbia, Vancouver, - - 2014
Hypertension is becoming increasingly prevalent among western societies. However, different ethnic groups appear to be affected unequally. This systematic review sought to evaluate blood pressure and hypertension among North American Indigenous populations. Electronic databases (e.g. MEDLINE and EMBASE) were searched and citations cross-referenced. Articles including blood pressure or hypertension among ...
Reddy Arun K AK aMount Sinai Heart, Icahn School of Medicine at Mount Sinai bJames J. Peters VA Medical Center, New York, New York, - - 2014
As the population above 60 years of age is the fastest growing and hypertension is highly prevalent in this group, accurate blood pressure (BP) measurement in the elderly is a very important and widely applicable subject. As with any other population, an accurate measurement of BP is essential to plan ...
Stawicki Stanislaw P A SP From the Division of Trauma, Critical Care, and Burn (S.P.A.S., D.S.E., D.C.E., C.N., D.E.L., C.H.C.), Department of Surgery, Department of Emergency Medicine (E.J.A.,CTB., D.P.B.), and Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine (N.A.A.), Department of Internal Medicine, The Ohio State University College of Medicine; Department of Anesthesiology (A.N.S.), The Ohio State College of Medicine; and OPUS 12 Foundation Multi-Center Trials Group (S.P.A.S., D.C.E., D.E.L., C.H.C., S.C.G., D.P.B.), Columbus, Ohio; Department of Anaesthesiology and Critical Care (J.M.B., S.V.), Jubilee Mission Medical College and Research Institute, Thrissur, Kerala; and Department of Emergency Medicine (S.C.G.), Global Hospital Group, Mumbai, - - 2014
In search of a standardized noninvasive assessment of intravascular volume status, we prospectively compared the sonographic inferior vena cava collapsibility index (IVC-CI) and central venous pressures (CVPs). Our goals included the determination of CVP behavior across clinically relevant IVC-CI ranges, examination of unitary behavior of IVC-CI with changes in CVP, ...
Clark Christopher E CE Primary Care Research Group, Institute of Health Services Research, University of Exeter Medical School, Exeter, - - 2014
The magnitude of the 'white coat effect', the alerting rise in blood pressure, is greater for doctors than nurses. This could bias interpretation of studies on nurse-led care in hypertension, and risks overestimating or overtreating high blood pressure by doctors in clinical practice. To quantify differences between blood pressure measurements ...
Ouatou Sanaa - - 2014
The goal of the study is to investigate the association between the APOA5 polymorphisms and haplotypes with Arterial Hypertension (AHT) in Moroccan patients. The study was performed in 283 subjects, 149 patients with AHT and 134 controls. All subjects were genotyped for the APOA5 -1131 T > C (rs662799), 56C ...
Castañón-Rodríguez J F - - 2014
High-pressure processing (HPP) combined with heat or cold has been proposed as an alternative quarantine process for Mexican fruit fly Anastrepha ludens Loew (Diptera: Tephritidae). HPP conditions at levels higher than 100 MPa applied to destroy eggs and larvae can also affect the postharvest physiology of the fruits. HPP at ...
Ivanovic Branislava - - 2014
The J-shaped relationship between blood pressure lowering and cardiovascular morbidity and mortality has been the topic of debates in the last three decades, especially because it has been shown that this relationship is not the same in different populations of hypertensive patients. This phenomenon is very important from a clinical ...
Patil Rohan Raosaheb RR Assistant Professor, Department of Community Medicine, Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur, Kancheepuram, Tamil Nadu, - - 2014
Objective: To study the prevalence of hypertension and variation in blood pressure (BP) level among school children in rural India. Design: A cross-sectional study was conducted during the period from April 2010 to March 2012. Setting: Participants comprised of 958 school children (in the age group of 6-16 years) from ...
- - 2014
According to a systematic review of four randomised trials in 8912 patients, antihypertensive therapy has not been shown to have a positive harm-benefit balance in people with blood pressure between 140/90 mmHg and 159/99 mmHg, but with no other cardiovascular risk factors.
Brankovic Suada S Faculty of Health Sciences, University of Sarajevo, Bosnia and - - 2014
Hypertension (high blood pressure) is one of the most widely spread diseases of our time and one of the leading risk factors for heart and vascular diseases, particularly stroke and coronary heart disease. According to the World Health Organization (WHO) cardiovascular diseases are the leading cause of death in the ...
Qiu Mingfeng M Department of Mechanical Engineering, University of Utah, Salt Lake City, UT 84112, - - 2014
The validity of the compressible Reynolds equation to predict the local pressure in a gas-lubricated, textured parallel slider bearing is investigated. The local bearing pressure is numerically simulated using the Reynolds equation and the Navier-Stokes equations for different texture geometries and operating conditions. The respective results are compared and the ...
Baradaran Azar A Department of Pathology, Isfahan University of Medical Sciences, Isfahan, - - 2014
Hypertension is a major risk factor for myocardial infarction, heart failure, stroke, peripheral arterial disease, and aortic aneurysm, and is a cause of chronic kidney disease. Hypertension is often associated with metabolic abnormalities such as diabetes and dyslipidemia, and the rate of these diseases is increasing nowadays. Recently it has ...
Matsumoto Akihiro A Department of Clinical Pharmacology and - - 2014
Although an association between high blood pressure and cognitive decline has been reported, no studies have investigated the association between home blood pressure and cognitive decline. Home blood pressure measurements can also provide day-to-day blood pressure variability calculated as the within-participant SD. The objectives of this prospective study were to ...
Chen Jinfeng J Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, - - 2014
An animal study reported that TGF-β1 maturation was linked to the homeostasis of blood pressure and elastogenesis of essential hypertension (EH). Recent advances require further research of TGF-β1 receptor in EH. A case-control study comprised of 2,012 adult hypertension case patients and 2,210 adult control subjects was conducted, and the ...
Liu Yanxia Y The Second Cadres Ward, General Hospital of Shenyang Military Area Command, Shenyang City, Liaoning Province 110840, - - 2014
The results of human clinical trials that have investigated the effects of resveratrol on blood pressure are inconsistent. We aimed to quantitatively evaluate the effects of resveratrol on systolic blood pressure (SBP) and diastolic blood pressure (DBP). We conducted a strategic literature search of PubMed, EMBASE, MEDLINE, and the Cochrane ...
Iimuro Satoshi S Clinical Research Support Center, The University of Tokyo Hospital, Tokyo, Japan, - - 2014
High prevalence of masked hypertension as well as persistent hypertension was observed in the Chronic Kidney Disease Japan Cohort (CKD-JAC) study. We proposed a novel indicator of blood pressure (BP) load, hyperbaric area index (HBI), calculated from ambulatory blood pressure monitoring (ABPM) data. The characteristic of this index and its ...
Balla Siham Ahmed SA University of Khartoum. - - 2014
Hypertension is emerging as an alarming public-health problem causes organ damage. To identify prevalence of hypertension and predictor factors among rural population in four states in Sudan. A community based cross-sectional study was conducted in sixteen rural areas in Sudan during April 2012. A total of 3020 adult were interviewed ...
Grossman Alon A Internal Medicine E Rabin Medical Center, Tel-Aviv, - - 2014
The association between exaggerated blood pressure (BP) response to exercise (ExBPR) and "masked hypertension" is unclear. Medical records of patients with high-normal BP who were evaluated in the Chaim Sheba Screening Institute Ramat Gan, Israel, during the years 2002-2007 and referred for 24-hour ambulatory BP monitoring (ABPM) and exercise test ...
Cho Jung Sun JS Department of Cardiology, Daejeon St. Mary's Hospital , Daejeon , Korea - - 2014
Abstract Morning blood pressure (BP) surge (MS) has been known to be a predictor of cardiovascular events. Currently, few studies have evaluated the underlying mechanism underlying MS, which may include neurohormonal factors and the renin-angiotensin-aldosterone system (RAAS). This study aimed to examine plasma aldosterone concentration (PAC) and plasma renin activity ...
Song Hongbin H Cardio-Cerebrovascular Control and Research Center, Institute of Basic Medicine, Shandong Academy of Medical Sciences , Jinan, Shandong , - - 2014
Abstract Background: Visit-to-visit variability in blood pressure (BP) was demonstrated to correlate with cardiovascular events independent of mean BP. The goal of the present study was to investigate the correlation of visit-to-visit BP variability with artery stiffness and myocardial perfusion in on-treated hypertensive patients. Methods: BP was measured in 271 ...
Hao Zilong Z Stroke Clinical Research Unit, Department of Neurology, West China Hospital, Sichuan University, Chengdu, - - 2014
Intracranial atherosclerotic stenosis is common in Asian, black, and Hispanic individuals. However, the management of blood pressure (BP) in the setting of acute stage in these patients is controversial. The present study aims to explore the relationship between BP on admission and outcomes in acute ischemic stroke patients with intracranial ...
Levi-Marpillat Natacha N 1] Department of Clinical Pharmacology, AP-HP, H.Mondor-A.Chenevier hospital, Créteil, France [2] Paris-Est University, Faculté de Médecine, Créteil, France [3] Neuropsychologie Interventionnelle, INSERM U955, Créteil, - - 2014
Increased blood pressure variability (BPV) contributes to end-organ damage, cardiovascular events and mortality associated with hypertension. In a cohort of 2780 hypertensive patients treated by either calcium channel blockers (CCBs), diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs) or β-blockers alone or in combination, we compared indices of short-term ...
Iritani Osamu O Department of Geriatric Medicine, Kanazawa Medical University, Ishikawa, - - 2014
A reduction of elevated blood pressure (BP) is an important treatment goal in elderly hypertensive patients. However, excessive reduction of systolic BP (SBP) and/or diastolic BP (DBP) might be harmful in such patients. We investigated whether this was the case with regard to risk of incident disability or death in ...
Shlomai Gadi G Department of Internal Medicine D and Hypertension Unit, The Chaim Sheba Medical Center, Tel-Hashomer Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, - - 2014
The objective of this study was to identify factors associated with the blood pressure (BP) response to spironolactone-aldosterone receptor antagonist as an add-on therapy in patients with resistant hypertension (HTN). We retrospectively reviewed the data of subjects with resistant HTN who were treated with add-on spironolactone in a large HTN ...
Hobbs D A DA 1] Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Whiteknights, Reading, Berkshire, UK [2] Institute for Cardiovascular and Metabolic Research (ICMR), University of Reading, Whiteknights, Reading, Berkshire, - - 2014
Our objective was to investigate whether the presence of Glu298Asp polymorphism in the endothelial NO synthase (eNOS) gene differentially affects the postprandial blood pressure response to dietary nitrate-rich beetroot bread. A randomised, single-blind, controlled, crossover acute pilot study was performed in 14 healthy men (mean age: 34±9 years) who were ...
Patel Anushka A The George Institute for Global Health, University of Sydney, - - 2014
Most individuals at high cardiovascular disease (CVD) risk worldwide do not receive any or optimal preventive drugs. We aimed to determine whether fixed dose combinations of generic drugs ('polypills') would promote use of such medications. We conducted a randomized, open-label trial involving 623 participants from Australian general practices. Participants had ...
Lammertyn Leandi L Hypertension in Africa Research Team (HART), North-West University (Potchefstroom Campus), Potchefstroom, South - - 2014
Hypertension is highly prevalent in black South Africans in which morbidity and mortality from stroke are on the increase. Elevated blood pressure and haemostatic markers can induce changes in blood rheology and endothelial function which could result in a procoagulant state that increases the risk for cerebrovascular disease. Information about ...
Afsar Baris B Konya Numune State Hospital, Department of Nephrology, Turkey. Electronic address: - - 2014
The current study aimed to investigate the relationship between morning blood pressure surge (MBPS), hemodynamic parameters, glycemic control and 24-h urinary sodium excretion (USE) in patients with type 2 diabetes mellitus (T2DM). MBPS and central hemodynamic parameters were assessed from ambulatory blood pressure measurements. In addition to routine biochemistry, 24h ...
Farias Serafin S Emergency Medicine, Baylor College of Medicine, Houston, TX. Electronic address: - - 2014
The effect profile of differing antihypertensive agents is well studied, but minimal data regarding the interaction between hemodynamic response and presenting blood pressure (BP) exist. Achievement of target BP is less likely in patients with higher initial BPs. This is a substudy of the multicenter safety and efficacy Evaluation of ...
Morley John E JE Divisions of Geriatric Medicine and Endocrinology, Saint Louis University School of Medicine, 1402 S. Grand Blvd., M238, St. Louis, MO, 63104, USA, - - 2014
Evidence for treatment of hypertension in older people is limited to placebo-controlled studies that reduced blood pressure in persons over 60 years who had systolic blood pressure >160 mmHg. Generally, physicians measure blood pressure poorly, failing to look for white coat or masked hypertension, orthostasis, postprandial hypotension, or pseudohypertension. There is evidence ...
Polonia Jorge J aFaculdade Medicina da Universidade do Porto, Porto, Portugal & Unidade Hipertensão, ULS Matosinhos bFaculdade Ciências Saúde, Universidade Fernando Pessoa & CHEDV, Epe, Feira cCHEDV, Epe, Feira dHospital Egas Moniz, Lisboa eSociedade Portuguesa de Hipertensão (Portuguese Society of Hypertension), - - 2014
To determine prevalence, awareness, treatment and control of hypertension and the 24-h sodium excretion (24h-UNa) in the Portuguese adult population and to examine their changes from a similar study done in 2003. A population-based cross-sectional survey conducted in 2011-2012. A multistage-stratified (by age and sex) sampling method was used to ...
Grübler Martin R MR Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical University of Graz, Graz, Austria; Department of Cardiology, Medical University of Graz, Graz, - - 2014
High aldosterone levels are considered to play a key role in arterial hypertension. Data on the relationship between the aldosterone to active renin ratio (AARR), a quantity of aldosterone excess, and ambulatory blood pressure (BP) monitoring (ABPM) during the night are, however, sparse. Hypertensive patients were recruited from local outpatient ...
Diedler Jennifer - - 2014
Current guidelines for spontaneous intracerebral hemorrhage (ICH) recommend maintaining cerebral perfusion pressure (CPP) between 50-70 mmHg, depending on the state of autoregulation. We continuously assessed dynamic cerebral autoregulation and the possibility of determination of an optimal CPP (CPPopt) in ICH patients. Assocations between autoregulation, CPPopt and functional outcome were explored. ...
Kawasaki Isao I Department of Metabolism and Endocrinology, Osaka City General Hospital, Osaka, - - 2014
We investigated the change in the urine albumin-to-creatinine ratio (ACR) to examine the effect of sitagliptin on diabetic nephropathy. Sitagliptin at a dose of 50 mg was administered to 247 outpatients with type 2 diabetes. Data was collected on the patients' laboratory results (including the ACR), blood pressure, and body ...
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