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Muller Majon M From the Laboratory of Epidemiology and Population Sciences (M.M., T.B.H., L.J.L.), Intramural Research Program, National Institute on Aging, Bethesda, MD; the Departments of Gerontology and Geriatrics (M.M.) and Radiology (M.v.B.), Leiden University Medical Center; Icelandic Heart Association (S.S., O.K., T.A., V.G.), Kopovagur; the Departments of Neurology & Radiology (O.K.) and Geriatrics (P.V.J.), Landspitali National University Hospital, Reykjavik, Iceland; the Department of Neurology (O.L.L.), University of Pittsburgh, PA; and the Faculty of Medicine (P.V.J.), University of Iceland, - - 2014
We hypothesized that in participants with a history of hypertension, lower late-life blood pressure (BP) will be associated with more brain pathology.METHODS: Participants are 4,057 older men and women without dementia with midlife (mean age 50 ± 6 years) and late-life (mean age 76 ± 5 years) vascular screening, cognitive ...
Dhaun Neeraj N From the BHF Centre of Research Excellence, University of Edinburgh, The Queen's Medical Research Institute, British Heart Foundation Centre of Research Excellence, Queen's Medical Research Institute, University of Edinburgh, Little France Crescent, Edinburgh, United Kingdom (I.M.M., V.M., W.O., R.A.K., K.E.B., E.D.K., D.J.W.); and Department of Renal Medicine, Royal Infirmary of Edinburgh, United Kingdom (N.D., J.G.). - - 2014
Hypertension and arterial stiffness are important independent cardiovascular risk factors in chronic kidney disease (CKD) to which endothelin-1 (ET-1) contributes. Loss of nocturnal blood pressure (BP) dipping is associated with CKD progression, but there are no data on 24-hour arterial stiffness variation. We examined the 24-hour variation of BP, arterial ...
Rosa Neto Nilton Salles NS From the Division of Rheumatology and the Hypertension Unit, the Heart Institute, Faculdade de Medicina da Universidade de São Paulo; and Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. N.S. Rosa Neto, MD, PhD; M. Levy-Neto, MD, PhD, Division of Rheumatology; E.C. Tolezani, MD, PhD, Hypertension Unit, the Heart Institute; E. Bonfá, MD, PhD, Division of Rheumatology; L.A. Bortolotto, MD, PhD, Hypertension Unit, the Heart Institute; R.M.R. Pereira, MD, PhD, Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo. Address correspondence to Dr. Pereira, Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455, 3º andar, sala 3105, São Paulo, SP, Brazil 01246-903. E-mail: rosamariarp@yahoo.com. Accepted for publication March 12, - - 2014
The assessment of pulse wave velocity (PWV) in Takayasu arteritis (TA) is complex because of many confounding factors. We evaluated PWV in female patients with TA and controls with comparable anthropometric and clinical variables and assessed a possible association of TA with disease variables. We evaluated 27 patients with TA ...
Sneed Rodlescia S RS Department of Psychology, Carnegie Mellon - - 2014
Objective: To determine if negative social interactions are prospectively associated with hypertension among older adults. Method: This is a secondary analysis of data from the 2006 and 2010 waves of the Health and Retirement Study, a survey of community-dwelling older adults (age > 50 years). Total average negative social interactions ...
Kızılırmak Pınar P Novartis Pharmaceuticals, İstanbul, Turkey. - - 2014
Objectives: This study evaluated the efficacy as well as the safety and tolerability profile of low-dose valsartan/amlodipine (Val/Amlo) single-pill combination (SPC) (160/5 mg) in patients with essential hypertension in Turkey. Study design: Adult patients with essential hypertension [systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) >90 mmHg], ...
Watson Hannah H Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow G12 8QQ, - - 2014
While negative effects of human disturbance on animals living above the ground have been widely reported, few studies have considered effects on animals occupying cavities or burrows underground. It is generally assumed that, in the absence of direct visual contact, such species are less vulnerable to disturbance. Seabird colonies can ...
Sobiczewski Wojciech W I Department of Cardiology, Medical University of Gdansk, Gdańsk, - - 2014
The goal of our study was to assess the influence of hypertension chronopharmacotherapy on diurnal blood pressure (BP) profile and mortality. Subjects with established coronary heart disease (CHD) (n=1345, mean age 63.2±9.2 years) were included. Non-dipping status was related to a lack of nighttime hypertensive drug administration (OR 3.87, 95% ...
Askari Sahar S Research Center for Development of Medical Studies, Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
There is no comprehensive report on seasonal variations in individuals' blood pressure (BP) in Iranian subjects. The aim of this study is to evaluate individuals' BP during the four seasons of the year in a large number of adults in Tehran. In a population-based study in Tehran, over a period ...
Anthony David D Memorial Hospital of Rhode Island, 111 Brewster St, Pawtucket, RI 02903, - - 2014
The 2013 American College of Cardiology/American Heart Association cholesterol guidelines depart from low-density lipoprotein (LDL) treatment targets and recommend treating four specific patient groups with statins. Statins are the only cholesterol-lowering drugs with randomized trial evidence of benefit for preventing atherosclerotic cardiovascular disease (ASCVD). The groups are patients with clinical ...
Edwards Elizabeth W EW Department of Medicine, University of South Carolina School of Medicine, Columbia, SC, - - 2014
The field of hypertension has evolved considerably over the last 70 years, from a belief that elevated blood pressure was an inevitable consequence of aging and beneficial, to maintaining perfusion to overwhelming proof of the cardiovascular morbidity and mortality associated with elevated blood pressure. The authors reviewed the literature on hypertension ...
Luo Jiewei - - 2014
To explore the relationship between Renying pulse (carotid) augmentation index (AI) and Cunkou pulse condition in different blood pressure groups, and the clinical significance of Renying and Cunkou pulse parameters to reflect vascular function. Eighty-six patients with essential hypertension (EH) and 52 individuals with normal blood pressure (control group) between ...
Souza Clarita Silva de CS Programa de Pós-Graduação em Ciências da Saúde: Cardiologia, Instituto de Cardiologia, Fundação Universitária de Cardiologia, Porto Alegre, RS, - - 2014
Background: Systemic hypertension is highly prevalent and an important risk factor for cardiovascular events. Blood pressure control in hypertensive patients enrolled in the Hiperdia Program, a program of the Single Health System for the follow-up and monitoring of hypertensive patients, is still far below the desired level. Objective: To describe ...
Rotenberg Lucia L Oswaldo Cruz Foundation, Rio de Janeiro, - - 2014
Night and shift work are suggested risk factors for hypertension. Considering the relationship between sleep deprivation and blood pressure, this study focuses on self-reported hypertension and napping during night shift. Our aims are (1) to analyse the prevalence of hypertension among day and night workers and (2) to test the ...
Nathan Hl H Women's Health Academic Centre, King's College London, London, - - 2014
Early recognition of haemodynamic instability following PPH is necessary to instigate interventions to prevent maternal morbidity and mortality. Conventional markers of haemodynamic compromise are relatively insensitive. To evaluate SI, the ratio of heart rate (HR) to systolic blood pressure (SBP), as a predictor of adverse clinical outcome following PPH, compared ...
Jones C C Barts and the London School of Medicine and Dentistry, London, - - 2014
The adverse effects of hypotension in neonates are well discussed, yet there is a limited understanding of the trends and consequences of slow blood pressure variability (BPV).(1,2) We hypothesised there would be different profiles of BPV and blood pressure (BP) in the first 72 hrs of life. Infants born < ...
Falaschetti Emanuela E Imperial Clinical Trials Unit, School of Public Health, Imperial College London, London, UK. Electronic address: - - 2014
Hypertension is the leading risk factor contributing to the global burden of disease. We aimed to assess the change in blood pressure management between 1994 and 2011 in England with a series of annual surveys. We did a serial cross-sectional study of five Health Survey for England surveys based on ...
Rapsomaniki Eleni E The Farr Institute of Health Informatics Research, London, UK; Epidemiology and Public Health, University College London, London, UK. Electronic address: - - 2014
The associations of blood pressure with the different manifestations of incident cardiovascular disease in a contemporary population have not been compared. In this study, we aimed to analyse the associations of blood pressure with 12 different presentations of cardiovascular disease. We used linked electronic health records from 1997 to 2010 ...
Strickland Amanda L - - 2014
Elevated urinary albumin to creatinine ratio (ACR) and white matter hyperintensity (WMH) volume seen on brain MRI are measures of microvascular disease which may have shared susceptibility to metabolic and vascular insults. We hypothesized that elevated ACR may be useful as inexpensive biomarker to predict presence of cerebral microvascular disease. ...
Kucukdurmaz Zekeriya Z Department of Cardiology, Medical School, Cumhuriyet University , Sivas , Turkey - - 2014
Abstract Non-dipper blood pressure (NDP) as an indicator of autonomic dysfunction could be associated with hypertensive response to exercise (HRE) in diabetic patients. HRE was determined as a predictor of development of unborn hypertension. We aimed to investigate if any correlation among NDP and HRE in normotensive type 2 diabetic ...
Zhang Dong-Hong DH Department of Clinical Laboratory, Peking Union Medical College Hospital and Peking Union Medical - - 2014
Background:Elevated homocysteine (Hcy) levels might play a role in the development of essential hypertension (EH). Telomere dynamics provide valuable insight into the pathogenesis of age-related diseases. The contribution of Hcy to leukocyte telomere length (LTL) shortening in EH and the underlying mechanism was examined.Methods and Results:LTL (ratio of the copy number of ...
Verwoert Germaine C GC aDepartment of Epidemiology bDepartment of Internal Medicine, Erasmus Medical Center, Rotterdam cDepartment of Biomedical Engineering dDepartment of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The - - 2014
We studied whether arterial stiffness measured as aortic pulse wave velocity (aPWV) and carotid distensibility was associated with different subtypes of hypertension in a large population of untreated middle-aged and elderly men and women. The study was conducted within the framework of the population-based Rotterdam Study. We included 4088 individuals ...
Grossman Alon A Department of Internal Medicine E, Rabin Medical Center, Beilinson Campus, Pethach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, - - 2014
Inter-arm blood pressure difference (IAD) is recognized as a risk factor for cardiovascular mortality. Its reproducibility in the elderly is unknown. The authors determined the prevalence and reproducibility of IAD in hospitalized elderly patients. Blood pressure was measured simultaneously in both arms on two different days in elderly individuals hospitalized ...
Musini Vijaya M VM Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, 2176 Health Science Mall, Vancouver, BC, Canada, V6T - - 2014
Hypertension is a modifiable cardiovascular risk factor. Although it is established that low-dose thiazides reduce mortality as well as cardiovascular morbidity, the dose-related effect of thiazides in decreasing blood pressure has not been subject to a rigorous systematic review. It is not known whether individual drugs within the thiazide diuretic ...
Liebeskind David S DS From the UCLA Stroke Center (D.S.L., R.J., J.L.S.); Emory University School of Medicine, Atlanta, GA (R.G.N.); and Medical College of Wisconsin, Froedtert Hospital, Milwaukee (O.O.Z.). - - 2014
Collaterals at angiography before endovascular therapy were analyzed to ascertain the effect on a novel end point of successful revascularization without symptomatic hemorrhage in the Solitaire FR With the Intention for Thrombectomy (SWIFT) study. Collateral grade (American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology) on baseline angiography was ...
Wang Anxin A aDepartment of Epidemiology and Health Statistics, School of Public Health bBeijing Municipal Key Laboratory of Clinical Epidemiology, Beijing cHebei United University dDepartment of Cardiology, Tangshan People's Hospital eDepartment of Cardiology, Kailuan Hospital, Hebei United University, Tangshan, China fDepartment of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany *Anxin Wang and Xiaoxue Liu contributed to this work and share the first authorship. Jost B. Jonas and Shouling Wu share the last - - 2014
Resting heart rate (RHR) is a predictive risk factor of the development of cardiovascular diseases, but its association with arterial hypertension has remained unclear. This study investigated the relationship between RHR and new-onset hypertension (NOH) in an Asian population. The Kailuan study is a prospective longitudinal cohort study on cardiovascular ...
Witham Miles D MD aAgeing and Health bDepartment of Clinical Pharmacology cEpidemiology and Biostatistics Unit dRobertson Centre for Biostatistics, University of Dundee, Dundee, - - 2014
Orthostatic hypotension commonly accompanies supine hypertension, and is associated with low 25-hydroxyvitamin D levels. We tested whether high-dose intermittent oral vitamin D therapy could ameliorate orthostatic hypotension in older patients with isolated systolic hypertension. We conducted a subgroup analysis of data from a parallel-group, double-blind, randomized, placebo-controlled trial. Patients aged ...
Makarov Alexey A AA Merck Sharp & Dohme Corp./Merck Research Laboratories, 126 East Lincoln Av., Rahway, NJ 07065, USA. Electronic address: - - 2014
Commercially available ultra high pressure liquid chromatography (UHPLC) equipment offers the ability to explore the influence of backpressure on chromatographic separations. However, the influence of pressure on the chromatographic separation of enantiomers on chiral stationary phases remains largely unexplored. In this investigation we surveyed the effects of pressure on the ...
Khalesi Saman S Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia, - - 2014
Although previous literature has reported that regular green tea consumption may improve blood pressure, the evidence from these studies is not consistent. The present study systematically reviewed randomised controlled trials and examined the effect of green tea consumption on blood pressure using meta-analysis. Search of ProQuest, PubMed, Scopus and Cochrane ...
Benavente Oscar R OR Department of Medicine, Division of Neurology, Brain Research Center, University of British Columbia, Vancouver, - - 2014
Neuroimaging manifestations of small vessel disease are heterogeneous, and correlation with patient features has not been adequately characterized. Our goal was to correlate magnetic resonance imaging findings with clinical features in a large multiethnic cohort with recent lacunar stroke. Patient characteristics were correlated with neuroimaging results in the Secondary Prevention ...
Kuppusamy Saranya S Department of Physiology - - 2014
Abstract Polycystic ovary syndrome (PCOS) is associated with cardiovascular risks like obesity, insulin resistance, dyslipidemia that can lead to sympathovagal imbalance (SVI). The study was designed to assess the cardiovascular risk in PCOS and link of metabolic derangements to SVI. Thirty-five newly diagnosed PCOS patients and 32 age-matched controls were ...
Surgit Ozgur O Cardiology Department, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital , Istanbul , Turkey - - 2014
Abstract Objective: Patients with a lack of nocturnal decline in blood pressure (BP) are at an increased risk for cardiovascular events. Mean platelet volume (MPV) and soluble CD40 ligand (sCD40L) are accepted biomarkers of platelet activation and considered as a risk factor for cardiovascular disease. The aim of this study ...
Amodeo Celso C Dante Pazzanese Institute, São Paulo, - - 2014
Morning blood pressure surge (MS), defined as the difference between the mean blood pressure (BP) 2 h after waking up and the mean of the three lowest BP values during sleep, has been correlated with increased cardiovascular risk. We sought to evaluate its association with cardiovascular events and death. We retrospectively ...
Do Ha T P HT Department of Community Nutrition, National Institute of Nutrition, Hanoi, Vietnam; Division of Human Nutrition; Wageningen University, Wageningen, The Netherlands. - - 2014
Hypertension has recently been identified as the leading risk factor for global mortality. This study aims to present the national prevalence of hypertension and prehypertension and, their determinants in Vietnamese adults. Nationally representative data were obtained from the National Adult Overweight Survey 2005. This one visit survey included 17,199 subjects ...
Charlson Mary E ME Center for Integrative Medicine, Weill Cornell Medical College, New York, New York. Electronic address: - - 2014
The objective of this prospective, longitudinal study of patients with normal-tension glaucoma (NTG) was to determine whether patients with nocturnal hypotension are at greater risk for visual field (VF) loss over 12 months than those without nocturnal hypotension. Prospective, longitudinal study. Consecutive patients with NTG with at least 5 prior ...
Rodríguez-Velamazán José Alberto JA Instituto de Ciencia de Materiales de Aragón, CSIC-Universidad de Zaragoza, C/Pedro Cerbuna 12, E-50009 Zaragoza, - - 2014
The effect of pressure (up to 0.17 GPa) on the spin-crossover compound {Fe(pmd)2[Ag(CN)2]2}n [orthorhombic isomer (II), pmd = pyrimidine] has been investigated by temperature- and pressure-dependent neutron Laue diffraction and magnetometry. The cooperative high-spin ↔ low-spin transition, centred at ca 180 K at ambient pressure, is shifted to higher temperatures as pressure ...
Robertson Andrew Donald AD Schlegel-University of Waterloo Research Institute for Aging - - 2014
Static cerebral autoregulation (sCA) is believed to be resistant to aging and hypertensive pathology. However, methods to characterize autoregulation commonly rely on beat-by-beat mean hemodynamic measures, and do not consider within-beat pulse wave characteristics that are impacted by arterial stiffening. We examined the role of critical closing pressure (CrCP) and ...
Obayashi Kenji K Department of Community Health and Epidemiology, Nara Medical University School of Medicine, Nara, - - 2014
Circadian blood pressure variability and melatonin secretion are both regulated by the biological clock. Several clinical trials have suggested that oral administration of exogenous melatonin lowers blood pressure at night, although it remains unclear whether melatonin secretion, which is considerably lower than pharmacological melatonin levels, is associated with nighttime blood ...
Imaizumi Yuki Y Munakata Oshima Clinic, Fukuoka, Japan; Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, - - 2014
Chronic hypoxia is a risk factor for cardiovascular disease, but its association with blood pressure (BP) remains unclear. We performed this study to clarify the hypothesis that chronic hypoxia is associated with abnormal BP variability in patients with pneumoconiosis. We recruited 19 patients with pneumoconiosis and 30 age- and BP ...
Horswill Catharine C British Antarctic Survey, High Cross, Cambridge, CB3 0ET, UK; Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow, G12 8QQ, - - 2014
Understanding the demographic response of free-living animal populations to different drivers is the first step towards reliable prediction of population trends. Penguins have exhibited dramatic declines in population size, and many studies have linked this to bottom-up processes altering the abundance of prey species. The effects of individual traits have ...
Merrill Ray M RM From the Department of Health Science, College of Life Sciences, Brigham Young University, Provo, - - 2014
To evaluate the effectiveness of a worksite wellness program in decreasing health risk. Analyses were based on 2411 employees from a school district in the western United States that participated in the WellSteps wellness program for 12 months. The numbers of high-risk employees at baseline were 683 for body mass ...
Chang Chiz-Tzung CT Division of Nephrology, China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, - - 2014
A decrease of systolic blood pressure in excess of 20 mmHg during hemodialysis treatment (IDD) is common for hemodialysis patients. Intradialysis hypotension (IDH) is symptomatic IDD by definition. Overproduction of nitric oxide (NO) is a possible cause of IDD. Dialysate nitrate and nitrite amount can be used as an indicator ...
Başar Cengiz C aDepartment of Cardiology, Düzce Atatürk State Hospital, Turkey Düzce State Hospital Departments of bCardiology cPathology, Düzce University Faculty of Medicine Hospital, Düzce dDepartment of Cardiology, Anatolia Hospital, Kastamonu eDepartment of Cardiology, Medeniyet University Faculty of Medicine Hospital, İstanbul, - - 2014
The aim of this study was to evaluate the relationship between left ventricular (LV) myocardial performance index (MPI) and nondipper pattern in hypertensive patients. Between June 2012 and November 2012, patients admitted to the Cardiology Department of Düzce University Faculty of Medicine and diagnosed previously with essential hypertension were included ...
Bi Mingda M Formulation Group, Pharmaceutical R&D, Amgen Inc, Thousand Oaks, California, - - 2014
The purpose of this study is to investigate if Johanson's rolling theory can correctly predict the maximum roll surface pressure during the roll compaction. Three model pharmaceutical formulations were roller compacted using the Gerteis Mini Pactor at multiple combinations of roll forces and roll gaps. The resultant ribbon density at ...
Lau Kui-Kai KK Division of Neurology, Department of Medicine, University of Hong Kong, Hong Kong, - - 2014
Blood pressure (BP) variability (BPV) is a novel risk factor for the development of atherosclerotic diseases. High BPV has recently been shown to predict all-cause and cardiovascular mortality in patients with lacunar infarct. Whether BPV has prognostic implications in patients with ischemic stroke subtypes, other than those due to small-vessel ...
Woodhead K K Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ, UK. - - 2014
The high pressure behavior of TaON was studied using a combination of Raman scattering, synchrotron X-ray diffraction, and X-ray absorption spectroscopy in diamond anvil cells to 70 GPa at ambient temperature. A Birch-Murnaghan equation of state fit for baddeleyite structured β-TaON indicates a high bulk modulus value Ko = 328 ...
Fuks Kateryna B KB IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, - - 2014
Long-term exposure to air pollution is hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country-specific. We investigated the cross-sectional association of long-term traffic-related air pollution with BP and prevalent hypertension in European populations. Fifteen population-based cohorts, participating in the European Study of Cohorts for Air ...
Maldonado João J Instituto de Investigação e Formação Cardiovascular/Clínica da Aveleira, Quinta da Portela, Rua Princesa Sindazunda Lote 9.3/Loja 94, 3030-503, Coimbra, - - 2014
Fixed-dose combinations of hypertensive drugs have been advocated as a suitable option for hypertensive patients who require two or more drugs to achieve blood pressure (BP) targets. Our objective was to assess the efficacy and safety of lercanidipine/enalapril in clinical practice. This observational study collected data for patients with hypertension ...
Mc Carthy Vera Jc VJ School of Nursing and Midwifery, Room 3.32 Brookfield Health Sciences Complex, University College Cork, Cork, Ireland. - - 2014
The effect of work on blood pressure (BP) in a general population with appropriate adjustment for confounders is not well defined. High job control has been found to be associated with lower BP and with nocturnal BP dipping. However, with older workers this may be compromised and has not been ...
Ismail Abdul Hamid AH *Philips Chair for Medical Information Technology, RWTH Aachen University, Pauwelsstrasse 20, 52074 Aachen, Germany §Department of Nephrology (Medical Clinic II), RWTH Aachen University Hospital, Pauwelsstrasse 30, 52074 Aachen, - - 2014
Using statistical methods, this study investigates whether bioimpedance spectroscopy (BIS) and plasma electrolytes can be used to identify risk of intradialytic hypotension (IDH) based on information obtained during the first half of the dialysis treatment only. Data obtained from 40 patients included information on blood pressure, parameters defined from BIS, ...
Gupta Punkaj P Division of Pediatric Critical Care, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Division of Pediatric Cardiology, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas. Electronic address: - - 2014
Little is known about the relation between center volume and outcomes in children requiring intensive care unit (ICU) admission for acute asthma. To evaluate the association of center volume with the odds of receiving positive pressure ventilation and length of ICU stay. Patients 2 to 18 years of age with ...
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