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Gulec Sadi S Department of Cardiology, Ankara University School of Medicine , Ankara, - - 2013
It is estimated that one out of three adults has hypertension and that more than 50% of them are unaware of this condition. Blood pressure screening can facilitate early diagnosis and reduce the risk of further complications associated with hypertension. However, disagreement between credible guidelines on major topics like diagnosis ...
Sengul Sule S Department of Nephrology, Ankara University School of Medicine , Ankara, - - 2013
Despite major progress in prevention, diagnosis, and treatment during the recent decades, hypertension remains the leading risk factor for cardiovascular disease and mortality throughout the world. The prevalence of hypertension in developing countries continues to rise reaching alarming rates. Several risk factors of hypertension appear to be more common in ...
Cappuccio Francesco P FP World Health Organization Collaborating Centre for Nutrition, University of Warwick, Warwick Medical School , Coventry, - - 2013
Salt is one of the most important determinants of high blood pressure and increased cardiovascular risk worldwide. However, a high salt intake has other adverse effects beyond those involving the cardiovascular system, so that there is renewed interest in the relationships between high salt intake and other diseases.
Sengul Sule S Department of Nephrology, Ankara University School of Medicine , Ankara, - - 2013
Worldwide, both hypertension and chronic kidney disease are major public health problems, due to their epidemic proportions and their association with high cardiovascular mortality. In 2003, the first Prevalence, awareness, treatment, and control of hypertension in Turkey (the PatenT) study was conducted in a nationally representative population (n=4910) by the ...
Ruilope Luis - - 2013
Central blood pressure (BP), an important measure of cardiovascular risk, has been shown to be effectively reduced by calcium channel blockade with amlodipine (AML) plus renin-angiotensin system blockade by the angiotensin-converting enzyme inhibitor, perindopril (PER). The aim of the SEVITENSION study was to compare the central effects of PER/AML against ...
Pagonas N - - 2013
There is increasing evidence that blood pressure variability (BPV, variation of blood pressure over time) constitutes a strong and independent marker of cardiovascular risk. The all-cause mortality is >50% greater in subjects with a standard deviation of inter-visit blood pressure >5 mm Hg. Regular aerobic exercise reduces blood pressure and is recommended ...
Dolan Eamon - - 2013
The term masked hypertension phenomenon was first described by the late Professor Thomas Pickering and is commonly defined as having a normal clinic blood pressure (BP) but an elevated "out of office" reading. In the main these elevated readings have been provided through ambulatory blood pressure monitoring (ABPM) but sometimes ...
Nelissen Heleen E - - 2013
To study the prevalence of target organ damage (TOD) in hypertensive adults in a general population in rural Nigeria, to assess determinants of TOD and the contribution of TOD screening to assess eligibility for antihypertensive treatment. All adults diagnosed with hypertension (nā€Š=ā€Š387) and a random sample (nā€Š=ā€Š540) out of all ...
McCarty Catherine A - - 2013
There have been numerous studies assessing the association of diet and blood pressure but little is known about the association between less commonly used nutritional supplements and blood pressured. The purpose of this study was to quantify the use of dietary supplements and their potential association with blood pressure in ...
Dahlberg Jonas - - 2013
We have previously shown that genetic variance in NEDD4L, a regulating protein of a sodium channel in the distal nephron, has been associated with marginally higher blood pressure and enhanced salt sensitivity. Here, we tested if the genetic NEDD4L variation previously associated with salt sensitivity is related to population blood ...
Wojnarowska Z Z Institute of Physics, University of Silesia, Uniwersytecka 4, 40-007 Katowice, - - 2013
In this Letter we report the relation between ionic conductivity and structural relaxation in supercooled protic ionic liquids (PILs) under high pressure. The results of high-pressure dielectric and volumetric measurements, combined with rheological and temperature-modulated differential scanning calorimetry experiments, have revealed a fundamental difference between the conducting properties under isothermal ...
Alici Hayri - - 2013
Nondipper pattern of blood pressure (BP) is associated with cardiovascular risk. In this study, we compared dipper versus nondipper patterns between normotensive patients with panic disorder (PD) and a control group. A total of 25 normotensive patients with PD and 25 controls were enrolled. Twenty-four-hour ambulatory BP monitoring was performed ...
Weinberg Ido I Institute for Heart Vascular and Stroke Care, Massachusetts General Hospital, Boston, - - 2014
An increased interarm systolic blood pressure difference is an easily determined physical examination finding. The relationship between interarm systolic blood pressure difference and risk of future cardiovascular disease is uncertain. We described the prevalence and risk factor correlates of interarm systolic blood pressure difference in the Framingham Heart Study (FHS) ...
Ojeda Norma B - - 2013
Experimental models of developmental programming provide proof of concept and support Barker's original findings that link birth weight and blood pressure. Many experimental models of developmental insult demonstrate a sex difference with male offspring exhibiting a higher blood pressure in young adulthood relative to their age-matched female counterparts. It is ...
Khosravi Ahmad - - 2013
To determine the prevalence of hypertension and pre-hypertension and its determinants in the 40-64 year old population of Shahroud in the north of Iran. The blood pressure of 5,190 of the 40-64 year old people participating in the first phase of Shahroud Eye Cohort Study was measured using the standard method. Sampling ...
Julius Stevo - - 2013
Previous studies reported increased white blood cell counts (WBCCs), an inflammatory marker, in hypertension, prehypertension and metabolic syndrome. Evidence suggests that inflammation precedes blood pressure (BP) elevation and may contribute to incident hypertension. Angiotensin receptor blockers (ARBs) may reduce inflammation. We analyzed WBCC trends in TRial Of Preventing HYpertension (TROPHY) ...
Hametner Bernhard - - 2013
Analysis of the arterial pressure curve plays an increasing role in cardiovascular risk stratification. Measures of wave reflection and aortic stiffness have been identified as independent predictors of risk. Their determination is usually based on wave propagation models of the circulation. Another modeling approach relies on modified Windkessel models, where ...
Avet John J Service de radiologie, CHU Nord, 42055 Saint-Étienne, France; Service de médecine nucléaire, CHU Nord, 42055 Saint-Étienne, - - 2013
Old age and hypertension are consistently reported to be the main risk factors of leukoaraiosis. The association between white matter lesions (WMLs) and other cardiovascular risk factors (CVRF) remains controversial. We evaluated the association between CVRF and WMLs in a cohort study and determined the blood pressure variables that could ...
Gillespie Cathleen D - - 2013
Hypertension is a major risk factor for heart disease and stroke. As the first and fourth leading causes of death in the United States, heart disease and stroke occur in approximately 30% of adults aged ≥18 years in the United States. Disparities in the prevalence of hypertension among racial/ethnic groups ...
Park Jae-Hyeong - - 2013
Reverse dipper, blood pressure (BP) rises during night-time, is a risk factor of increased cardiovascular events in hypertensive patients. However, we have little information whether reverse dipper in acute stage of cerebral infarction (CI) affects on the recurrence and mortality. We studied to assess the relationship between reverse dipper and ...
Chan Q - - 2013
Inverse associations have been reported of overall vegetable intake to blood pressure (BP); whether such relations prevail for both raw and cooked vegetables has not been examined. Here we report cross-sectional associations of vegetable intakes with BP for 2195 Americans ages 40-59 in the International Study of Macro/Micronutrients and Blood ...
Shaw Brett H - - 2013
Falls are devastating events and are the largest contributor towards injury-related hospitalization of older adults. Orthostatic hypotension (OH) represents an intrinsic risk factor for falls in older adults. OH refers to a significant decrease in blood pressure upon assuming an upright posture. Declines in blood pressure can reduce cerebral perfusion; ...
Delgado Luis Carlos - - 2013
This study analyzes differences in blood pressure (BP) and baroreflex sensitivity (BRS) in relation to trait worry. Thirty-six high worry and 21 low worry females were selected from scores on the Penn State Worry Questionnaire. Cardiovascular parameters were obtained during rest, a self-induced worry period, and defense reflex to intense ...
O'Flynn Claire C CC Department of Meat Technology, Teagasc Food Research Centre, Ashtown, Dublin 15, - - 2013
This study investigated the effects of high pressure (HP) treatment of pork meat before manufacturing sausages with reduced salt levels and compared them to sausages manufactured with untreated meat (control sausages). A 2×5 factorial design was set up incorporating two pressure levels (0 or 150MPa) and five salt levels (0.5, ...
Shu Wang W The Cardiovascular Medical Department of the General Hospital of Chinese People of Liberation Army, Fu Xin Road Number 28, Beijing 100853, - - 2014
In our previous study, we had shown that high diastolic blood pressure (DBP) was positively related to well-developed coronary collateral circulation (CCC). This study sought to find out the more precise relationship between DBP and CCC. To investigate this, we conducted a study of 671 patients with single chronic total ...
Euteneuer Frank - - 2013
Objective: Living in adverse neighborhood conditions has been linked with greater prevalence of cardiovascular disease (CVD). We aimed to learn whether perceived neighborhood problems are related to attenuated nocturnal blood pressure (BP) dipping, a risk factor for CVD morbidity. Method: A sample of 133 adults (71 male, 62 female; 80 ...
Lerch Michael T MT Jules Stein Eye Institute and Department of Chemistry and Biochemistry, University of California, Los Angeles, CA - - 2013
Excited states of proteins may play important roles in function, yet are difficult to study spectroscopically because of their sparse population. High hydrostatic pressure increases the equilibrium population of excited states, enabling their characterization [Akasaka K (2003) Biochemistry 42:10875-85]. High-pressure site-directed spin-labeling EPR (SDSL-EPR) was developed recently to map the ...
Glasser Stephen P - - 2013
Alterations in cardiovascular structure and function have been shown to precede the finding of elevated blood pressure. This study is part of the Hypertension Genetic Epidemiologic Network (HyperGEN) in which genetic and environmental determinants of hypertension were investigated in 5 geographical field centers. All nonhypertensive offspring (n = 1,035) were ...
Johansson Jouni K - - 2013
The objective of this study was to elucidate the usefulness of both the oscillometric blood pressure (OBP) and auscultatory blood pressure (ABP) measurement technique in the assessment of blood pressure (BP) and target organ damage in the general population. We studied a sample of the Finnish adult population aged 25-74 ...
Agrawal Ritesh - - 2013
Prospective studies comparing the efficacy of selective versus nonselective alpha blockers for preoperative preparation of pheochromocytoma (PCC) are lacking. In this prospective nonrandomized study, we compared the outcome of preoperative preparation with phenoxybenzamine (PBZ) and prazosin (PRZ) in terms of perioperative hemodynamic alterations. The study was conducted at a tertiary ...
Tsioufis Costas - - 2013
Little is known regarding the clinical course and prognosis of resistant hypertension (RHT). We evaluated predictors of persistent RHT and the associated cardiovascular risk. We studied 1911 treated hypertensive patients (aged 59±11 years, 49% men) for a mean period of 3.9 years. At baseline, clinical data were collected and patients ...
Nuwaha Fred - - 2013
Persons with a systolic blood pressure (BP) of 120 to < 140 or diastolic BP of 80 to < 90 mm hg are classified as having pre-hypertension. Pre-hypertension is associated with cardiovascular disease (CVD) risk factors, incident CVD and CVD mortality. Understanding determinants of pre-hypertension especially in low income countries ...
Abad-Pérez Daniel - - 2013
Isolated systolic hypertension is a highly prevalent disease among the elderly. The little available evidence on the efficacy of nitrates for treating the disease is based on small experimental studies.Methods/design: We performed a multicenter, randomized, double-blind, phase III, placebo-controlled trial in 154 patients aged over 65 years with refractory isolated ...
van Middendorp Deborah - - 2013
Globally, about 350.000 women die every year from pregnancy related causes and more than half of these deaths occur in sub-Saharan Africa (SSA). Approximately 12% of the maternal deaths are associated with hypertensive disorders in pregnancy such as pregnancy induced hypertension (PIH). However, very little is known about PIH and ...
Mehta Amar J - - 2013
We investigated associations between short-term exposure to air pollution and central augmentation index and augmentation pressure, correlates of arterial stiffness, in a cohort of elderly men in the Boston, Massachusetts, metropolitan area. This longitudinal analysis included 370 participants from the Veterans Affairs Normative Aging Study with up to 2 visits ...
Karpinos Ashley Rowatt - - 2013
<0.001) and final (19.2% versus 10.2%; P=0.001) years of athletic participation. In adjusted analyses, the odds of hypertension were higher among football athletes in the initial year (adjusted odds ratio, 2.28; 95% confidence interval, 1.21-4.30) but not in the final year (adjusted odds ratio, 1.25; 95% confidence interval, 0.69-2.28). Over ...
Harrell John W - - 2013
Poor cerebrovascular function in metabolic syndrome (MetSyn) likely contributes to elevated risk of cerebrovascular disease in this growing clinical population. Younger MetSyn adults without clinical evidence of cerebrovascular disease exhibit preserved hypercapnic vasodilation yet markedly impaired hypoxic vasodilation, but the mechanisms behind reduced hypoxic vasodilation are unknown. Based on data ...
Qi Yue - - 2013
The replication of genome-wide significant association signals in independent populations is a practical approach for characterizing gene-disease relationships. Therefore, we sought to explore the top 10 polymorphisms from a large blood pressure genome-wide association study of northeastern Han Chinese East Asians. This was a hospital-based study involving 1009 patients with ...
Shao Li - - 2013
Obestatin, encoded by the same gene as ghrelin, was first described as a physiological opponent of ghrelin. The association between circulating obestatin levels and blood pressure remains unclear. Furthermore, adequate information is non-existent regarding the older male population with hypertension. For this purpose, we enrolled 185 unrelated hypertensive male patients ...
Pal Gopal Krushna - - 2013
Abstract Purpose . Assessment of short-term practice of relaxation therapy on autonomic and cardiovascular functions in first-year medical students. Design . Case-control, interventional study. Setting . Medical college laboratory. Subjects . Sixty-seven medical students, divided into two groups: study group (n = 35) and control group (n = 32). Intervention ...
Wenk H-R - - 2013
Transition metals Ti, Zr, and Hf have a hexagonal close-packed structure (α) at ambient conditions, but undergo phase transformations with increasing temperature and pressure. Of particular significance is the high-pressure hexagonal ω phase which is brittle compared to the α phase. There has been a long debate about transformation mechanisms ...
Malard Lucile - - 2013
The Angiotensin-Converting Enzyme-2 (ACE2) gene, located on chromosome X, is believed to be implicated in blood pressure regulation. However the few studies that have examined this association have yielded mixed results. The objective of this study was to assess the association between tag single nucleotide polymorphisms (SNPs) in the angiotensin-converting ...
Becker Amy M AM Division of Nephrology, Dallas, - - 2014
Kidney disease is an important cause of morbidity and mortality in patients with sickle cell anemia (SCA). The factors that affect progression of renal disease are unknown, especially in children and adolescents. Alterations in blood pressure, including hypertension and lack of the normal nocturnal dip in blood pressure, are important ...
Rahimi Kazem - - 2013
The development of effective pharmacological strategies for lowering blood pressure was one of medical science's major success stories of the 20(th) century. Blood pressure was proven beyond doubt to be causally and continuously related to future risk of cardiovascular events,(1) and lowering blood pressure was proven to reduce that risk.(2-4) ...
Yi Stella - - 2013
Characterization of health conditions in recent immigrant subgroups, including foreign-born whites and Asians, is limited but important for identifying emerging health disparities. Hypertension, a major modifiable risk factor for cardiovascular disease, has been shown to be associated with acculturation, but the acculturative experience varies for different racial/ethnic groups. Assessing the ...
Trudu Matteo M Dulbecco Telethon Institute, Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, - - 2013
Hypertension and chronic kidney disease (CKD) are complex traits representing major global health problems. Multiple genome-wide association studies have identified common variants in the promoter of the UMOD gene, which encodes uromodulin, the major protein secreted in normal urine, that cause independent susceptibility to CKD and hypertension. Despite compelling genetic ...
Ujunwa Fortune A - - 2013
Hypertension is a prevalent cardiovascular disease risk factor among blacks and adolescent hypertension can progress into adulthood. To determine the prevalence of hypertension and prehypertension among secondary school adolescents in Enugu South East Nigeria.Methodology: A study of 2694 adolescents aged 10-18 years in Enugu metropolis was carried out . Socio-demographic ...
Dluholucký Svetozár S The Slovak Medical University in Bratislava, Faculty of Health, Banská Bystrica, Slovakia. - - 2013
The broad spectrum of extraosseal functions of vitamin D has recently been investigated. Although majority of recent studies have documented its hypotensive effect, some older studies warrant the risk of development the juvenile hypertension namely after pulse-fortified D vitamin supplementation during infancy. The aim of this study was to compare ...
Turchi F F Division of Endocrinology, Università Politecnica delle Marche, Ospedali Riuniti "Umberto I-G.M. Lancisi-G.Salesi", Via Conca 71, Ancona 60126, Italy; Department of Diabetology and Endocrinology, Asur Marche Area Vasta 1, S. Maria della Misericordia Hospital, Urbino, - - 2013
Primary aldosteronism (PA), the most frequent form of secondary hypertension, is characterized by a higher rate of cardiovascular (CV) events than essential hypertension (EH). Aim of the study was to evaluate the cardiovascular risk according to the ESH/ESC 2007 guidelines, in patients with PA and with EH, at diagnosis and ...
Fuchs Sandra C - - 2013
The available, albeit rare, evidence indicates the superiority of home- over office blood pressure monitoring (HBPM vs OBP) to predict cardiovascular (CV) outcomes. We performed a systematic review to update the efficacy of HBPM vs OBP as predictors of all-cause mortality, CV death, and target organ damage. Two reviewers independently ...
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