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Bhatia Sonal - - 2012
"Hypertensive" variant of congenital adrenal hyperplasia is rare. The authors describe an interesting case of a 6-y-old boy who presented with an acute respiratory illness and progressive breathlessness since 1 y. Genital hyperpigmentation was noticed since 2 y of age; the onset of pubarche and increasing penile size at 4 y. He was ...
Leatherman James W - - 2012
BACKGROUND: Expiratory muscle activity may cause the end-expiratory central venous pressure (CVP) to greatly overestimate right atrial transmural pressure. METHODS: We recorded CVP and expiratory change in intra-abdominal pressure (ΔIAP) in 39 patients who had a respiratory excursion in CVP from end-expiration to end-inspiration (CVP(ee)-CVP(ei)) ≥8 mmHg. Uncorrected CVP was measured at ...
Mortensen Kristian Havmand - - 2012
Objective:  Carotid intima-media thickness (IMT) may potentially supplement cardiovascular risk assessment in Turner syndrome (TS), where cardiovascular risk is high and appropriate risk stratification difficult. Knowledge of intima-media thickness in TS is scarce, and this study aimed to enhance insight into the cardiovascular risk marker. Design, Patients and Measurements:  IMT ...
Gomez-Laberge C - - 2012
Patients with acute lung injury or acute respiratory distress syndrome (ALI/ARDS) are vulnerable to ventilatorinduced lung injury. Although this syndrome affects the lung heterogeneously, mechanical ventilation is not guided by regional indicators of potential lung injury. We used electrical impedance tomography (EIT) to estimate the extent of regional lung overdistension ...
Worsøe J - - 2012
Background:Constipation and fecal incontinence are considerable problems for most individuals with spinal cord injury (SCI). Neurogenic bowel symptoms are caused by several factors including abnormal rectal wall properties. Stimulation of the dorsal genital nerve (DGN) can inhibit bladder contractions and because of common innervation inhibitory effects are anticipated in the ...
Peralta Carmen A CA Department of Medicine, San Francisco VA Medical Center, San Francisco, California, USA. - - 2012
Treatment of hypertension is difficult in chronic kidney disease (CKD), and blood pressure goals remain controversial. The association between each blood pressure component and end-stage renal disease (ESRD) risk is less well known. We studied associations of systolic and diastolic blood pressure (SBP and DBP, respectively) and pulse pressure (PP) ...
Ertas Faruk - - 2012
Objective. Epicardial fat has been proposed as a new cardiometabolic risk factor. Although epicardial fat thickness (EFT) is associated with hypertension, the relationship between diurnal blood pressure profiles and EFT is still unknown. The purpose of this study is to investigate the association between the echocardiographic EFT and diurnal blood ...
Fujiwara M - - 2012
Objectives: The aim of this study was to report the long-term outcome of the surgical palliation of pulmonic stenosis in dogs. Methods: The subjects comprised three female and six male dogs, mean (±sd) age: 23 (±25) months, mean (±sd) weight: 3·4 (±2·1) kg, diagnosed with severe pulmonic stenosis and right ...
Rosenbaum David - - 2012
Twenty-four-hour ambulatory blood pressure monitoring (ABPM) has been shown to be more reliable than conventional measurements for hypertension assessment and the associated increased risk of cardiovascular events. Olmesartan/hydrochlorothiazide combination therapy has demonstrated increased blood pressure lowering over 24 hours compared with the component monotherapies. This prespecified pooled analysis of data ...
Fontana Vanessa - - 2012
Growing experimental evidence indicates that matrix metalloproteinases (MMPs) are implicated in many cardiovascular diseases including hypertension and its chronic complications. It is now clear that MMPs have many more substrates other than components of the extracellular matrix. In fact, intracellular targets now include those associated with the cardiovascular system. Clinical ...
Simonetti G - - 2012
PURPOSE: This study was done to investigate the efficacy and safety of percutaneous renal denervation with the Symplicity catheter for reducing blood pressure in patients with essential hypertension resistant to medical therapy (systolic blood pressure >160 mmHg despite the use of three or more antihypertensive drugs, including a diuretic). MATERIALS ...
Gama de Abreu Marcelo - - 2012
PURPOSE OF REVIEW: We aimed at providing the most recent and relevant evidence regarding spontaneous breathing activity during mechanical ventilation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Both clinical and experimental data are depicted. RECENT FINDINGS: The use of unsupported spontaneous breathing has been associated with ...
Silva Rita de Cássia Gengo E - - 2012
BACKGROUND: Arterial hypertension is an important risk factor for Lower-Limb Occlusive Arterial Disease (LLOAD). However, the correlation between blood pressure and pulse pressure (PP) with LLOAD severity and functional impairment resulting from this disease is not well established in the Brazilian population. OBJECTIVE: To verify whether there is a correlation ...
Refai Majed - - 2012
OBJECTIVESDigitalized chest drainage systems allow for quantification of air leak and measurement of intrapleural pressure. Little is known about the value of intrapleural pressure during the postoperative phase and its role in the recovering process after pulmonary resection. The objective of this investigation was to measure the values of pleural ...
Hadaegh F - - 2012
Data are conflicting and sparse regarding the impact of high normal blood pressure (BP) (systolic BP (SBP) of 130-139 mm Hg or diastolic BP (DBP) of 85-89 mm Hg) on incident cardiovascular disease (CVD) among middle-aged vs elderly population. We examined the risk of BP categories among 6273 participantsī‹¶30 years, free of CVD at ...
Mandry Damien - - 2012
OBJECTIVES:: To determine, using a comprehensive MRI investigation, prevalence and vascular correlates of early left-ventricular concentric remodeling in middle-aged patients with abdominal obesity. Left-ventricular and vascular remodeling are commonly associated with hypertension, but little is known for abdominal obesity patients, a population with definite increase in cardiovascular risk and high ...
Malyszko Jolanta - - 2012
Most patients on dialysis are hypertensive and their blood pressure (BP) control is often poor. Renalase is preferentially expressed in proximal tubules, but it is also present in glomeruli and distant tubules, as well as in cardiomyocytes, liver, and skeletal muscle. It had been proposed that renalase had a flavin ...
Erdine Serap - - 2012
Clinical studies and population-based analyses show that in patients with hypertension, the majority cannot control their blood pressure (BP) by treatment with a single antihypertensive agent. Combining agents from different antihypertensive classes with complementary modes of action significantly increases efficacy and is a treatment strategy recommended by European treatment guidelines, ...
Giuliano Karen K - - 2012
Current monitoring systems for patients receiving vasopressor support generally rely on bedside monitors with audible alarms that are activated when blood pressure declines below pre-established thresholds, which can result in fluctuations that may increase risk of myocardial ischemia. This pilot study evaluated the effects of three bedside monitors on mean ...
Kosmin Michael A - - 2012
PURPOSE: Radiolabelled meta-iodobenzylguanidine (mIBG), used as targeted therapy for neuroblastoma, is known to have effects on blood pressure (BP). In this study we audited BP changes in patients receiving (131)I-mIBG therapy for neuroblastoma to identify BP-related adverse events (AE) and possible predictive factors. METHODS: Between 2003 and 2010, 50 patients ...
Wémeau-Stervinou Lidwine - - 2012
RATIONALE: Diffusing capacity of the lung for carbon monoxide (DLCO) is a good marker of disease severity in patients with idiopathic interstitial pneumonia (IIP). The combined diffusing capacity of nitric oxide (DLNO) and DLCO determines the two components of diffusion: membrane conductance (Dm, CO) and pulmonary capillary blood volume (Vc). ...
Trombley Kathy K North Shore University Hospital, Manhasset, NY 11030, - - 2012
A group of palliative care nurses wanted to investigate the phenomenon they were witnessing in their end-of-life patients. There was a rapid onset of skin change characterized by bruising on various parts of the body in these patients. Traditionally they were described as pressure ulcers. However, the skin changes did ...
Raimann Jochen G - - 2012
The association between changes in systolic and diastolic blood pressure, and the use of cardioprotective drugs on survival of incident hemodialysis patients, was examined in this retrospective cohort study. Pre-hemodialysis systolic and diastolic blood pressures were averaged over the first month of hemodialysis. Slopes, reflecting temporal changes, were computed by ...
Laiteerapong Neda - - 2012
In patients with diabetes, delays in controlling blood pressure are common, but the harms of delays have not been quantified. To estimate the harms of delays in controlling systolic blood pressure in middle-aged adults with newly diagnosed Type 2 diabetes. Decision analysis using diabetes complication equations from the United Kingdom ...
Muxfeldt Elizabeth S - - 2012
Resistant hypertension is defined as uncontrolled office blood pressure, despite the use of ≥3 antihypertensive drugs. Ambulatory blood pressure monitoring (ABPM) is mandatory to diagnose 2 different groups, those with true and white-coat resistant hypertension. Patients are found to change categories between controlled/uncontrolled ambulatory pressures without changing their office blood ...
Ye Dan - - 2012
This research aimed to analyze the clinical data of various etiologies of hypertension in patients hospitalized in the Endocrinology Division. The differences between essential and secondary hypertension were examined to provide a basis for clinical differential diagnosis. The data from all the inpatients with hypertension of unknown origin admitted in ...
Mizuno Masashi - - 2012
OBJECTIVE: We have shown that as renal function deteriorates, the circadian blood pressure (BP) rhythm shifts to a nondipper pattern and the duration until nocturnal BP decline [dipping time (DT)] is prolonged. We investigated whether or not morning hypertension (BP 2 h after awakening >135/85 mmHg) in chronic kidney disease ...
Odedosu Taiye - - 2012
Barriers to blood pressure control exist at the patient, physician, and system levels. We review the current evidence for interventions that target patient- and physician-related barriers, such as patient education, home blood pressure monitoring, and computerized decision-support systems for physicians, and we emphasize the need for more studies that address ...
Kataoka Toshiyuki - - 2012
Although capitate shortening for Kienbock's disease decompresses the radiolunate joint, the distal carpal row migrates proximally postoperatively and the carpal alignment subsequently collapses. We hypothesised that partial capitate shortening, in which only the lunate facet of the capitate is shortened and the scaphocapitate joint is preserved, could achieve adequate decompression ...
Ruppel Gregg L - - 2012
Lung volumes are considered part of a complete pulmonary function test, but their value for enhancing clinical decision making is unknown. Unlike spirometry and diffusing capacity of the lung for carbon monoxide (D(LCO)), which do contribute to confirming or excluding a diagnosis, there are few clear indications when lung volumes ...
Hashemi Javad J Department of Electrical and Computer Engineering, School of Computing, Queen’s University, Kingston, ON K7L 3N6, Canada. - - 2012
A modification method based on integrated contact pressure and surface electromyogram (SEMG) recordings over the biceps brachii muscle is presented. Multi-site sEMGs are modified by pressure signals recorded at the same locations for isometric contractions. The resulting pressure times SEMG signals are significantly more correlated to the force induced at ...
Gaddam Krishna K - - 2012
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC-7) defines hypertension as systolic blood pressure (BP) ≥140 mmHg or diastolic BP ≥90 mmHg. The JNC-7 defines 'prehypertension' to include systolic BP values between 120 and 139 mmHg and diastolic BP ...
Hasegawa Hiroshi H Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chuo-ku, Chiba, - - 2012
The Candesartan Cooperative Research of Therapy Design for Early Morning Hypertension in CHIBA was designed to investigate whether switching from angiotensin II receptor blockers (ARBs) except candesartan to candesartan might be effective in Japanese patients with morning hypertension. Seventy-eight mild to moderate hypertensive patients, who were treated with the standard ...
Gandolfi Stefano - - 2012
Purpose. To demonstrate that the intraocular pressure (IOP)-lowering effect of travoprost 0.004% preserved with polyquaternium-1 (travoprost benzalkonium chloride [BAK]-free) is non-inferior to that of travoprost 0.004% preserved with benzalkonium chloride (travoprost BAK) in patients with ocular hypertension or open-angle glaucoma. Methods. A total of 371 patients randomly received travoprost BAK-free ...
Monnet Xavier - - 2012
We tested whether the poor ability of pulse pressure variation to predict fluid responsiveness in cases of acute respiratory distress syndrome was related to low lung compliance. We also tested whether the changes in cardiac index induced by passive leg-raising and by an end-expiratory occlusion test were better than pulse ...
Kurniawan Emil D - - 2012
Retinal vascular fractal dimension (D(f)) is a measure of the geometric complexity of the retinal microvasculature, and has been associated with diabetic retinopathy. In this study, the authors examined the relationship between blood pressure and retinal D(f) in children. Among 1174 children aged 10 to 14 years who participated in ...
Thoenes Martin - - 2012
Background. We investigated the association between blood pressure control and common cardiometabolic risk factors from a global and regional perspective. Methods. In the present analysis of a large cross-sectional i-SEARCH study, 17.092 outpatients receiving antihypertensive treatment were included in 26 countries. According to clinical guidelines for the management of arterial ...
Pollay Michael - - 2012
It was firmly established in the mid-twentieth century that the arachnoid villi represented an open pathway between the subarachnoid space and the dural venous sinuses. Intracellular and extracellular pathways within the villous structure provided the conduit for cerebrospinal fluid (CSF) and particulate matter. The importance of the lymphatic system was ...
Celik Atac - - 2012
Cardiotrophin-1 (CT-1) is a member of the interleukin (IL-6) family of cytokines and is increased in various cardiovascular diseases, including chronic heart failure. The aim of the study was to determine if plasma CT-1 is associated with diastolic heart failure (DHF) and to investigate the relationship between CT-1 and echocardiographic ...
Mpakopoulou Maria - - 2012
Aim: The aim of this study was to present our 10-year experience with the use of fixed-pressure and programmable valves in the treatment of adult patients requiring cerebrospinal fluid (CSF) diversion. Material and methods: Patients (n = 159; 89 male and 70 female) suffering from hydrocephalus of various causes underwent ...
Suehiro Kotaro K Division of Vascular Surgery, Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, - - 2012
To evaluate the interface pressure (IP) and stiffness of our elastic multilayer bandages (eMLB). Three medical staff wrapped the legs of 10 healthy volunteers with one to six rolls of elastic bandages. The IP was measured at the medial aspect of the lower leg at the level of transposition of ...
Parsons Brian A - - 2012
Characterizing the integrative physiology of the bladder requires whole organ preparations. The purpose of this study was to validate an isolated large animal (pig) bladder preparation, through arterial and intravesical drug administration, intravesical pressure recording, and filming of surface micromotions. Female pig bladders were obtained from the local abattoir and ...
- - 2012
: All major guidelines for antihypertensive therapy recommend weight loss. Thus dietary interventions that aim to reduce body weight might be a useful intervention to reduce blood pressure and adverse cardiovascular events associated with hypertension. : Primary objectivesTo assess the long-term effects of weight-reducing diets in hypertension patients on To ...
Delsart Pascal - - 2012
The chronic management of post-acute aortic dissection (AD) of the descending aorta (Type B) is based on optimal control of blood pressure (BP), with a target BP < 135/80 mmHg. The aim of our study was to determine and verify effective blood pressure control with an objective measurement method and ...
Rodriquez Dario D - - 2012
Mechanical ventilation in an austere environment is difficult owing to logistics, training, and environmental conditions. We evaluated the ability of professional caregivers to provide ventilatory support to a simulated patient using the Simplified Automated Ventilator (SAVe) with a mask hand attended ventilation, mask with single strap unattended ventilation, and supraglottic ...
Chkeir Aly A University of Technology of Troyes (UTT), Troyes, France. - - 2012
Grip-strength measurement is a key element in the evaluation of numerous conditions including frailty. An innovative grip-strength evaluation tool, the Grip-Ball has been developed for remote assessment of grip-strength. The Grip-Ball is an airtight ball that can be inflated to different pressures, thus varying the stiffness of the ball and ...
Aptel Florent - - 2012
Purpose. To evaluate the intraocular pressure (IOP)-lowering effects and tolerability of the 3 prostaglandin-timolol fixed combinations (PG-timolol FCs). Methods. Clinical trials comparing directly the PG-timolol FCs or comparing the PG-timolol FCs to their individual components were thoroughly searched. The main outcome measures were efficacy assessed by IOP (taken at 9 ...
Stead Latha Ganti - - 2012
To assess relationships between blood pressure hemodynamic measures and outcomes after acute ischemic stroke, including stroke severity, disability and death. The study cohort consisted of 189 patients who presented to our emergency department with ischemic stroke of less than 24 hours onset who had hemodynamic parameters recorded and available for ...
Haas Carl F - - 2012
In addition to improving gas exchange by mechanical ventilation, minimizing iatrogenic lung injury and making the patient comfortable are important goals. This article reviews advanced ventilator modes and techniques that might help to accomplish these goals. Small tidal volumes (VT) and low ventilation pressure minimize ventilator-induced lung injury. Airway pressure ...
Holena Daniel N - - 2012
A comatose 23-year-old woman with acute liver failure due to an overdose of acetaminophen had indications of intracranial hypertension and underwent liver transplantation. Her level of arousal did not improve, and on postoperative day 1, clinical signs of cerebral herniation became apparent. An intracranial pressure monitor was placed, and intracranial ...
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