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Results 101 - 150 of 2348
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Lin Pao-Yuan - - 2012
Background: Perforator-based fasciocutaneous flaps for reconstructing pressure sores can achieve good functional results with acceptable donor site complications in the short-term. Recurrence is a difficult issue and a major concern in plastic surgery. In this study, we introduce a reusable perforator-preserving gluteal artery-based rotation flap for reconstruction of pressure sores, ...
Schädler Dirk - - 2012
RATIONALE: In spite of its ability to reduce overall ventilation time, protocol-guided weaning from mechanical ventilation is not routinely used in daily clinical practice. Clinical implementation of weaning protocols could be facilitated by integration of knowledge-based, closed loop-controlled protocols into respirators. OBJECTIVE: To determine whether automated weaning decreases overall ventilation ...
Myers Martin G - - 2012
Manual blood pressure (BP) is gradually disappearing from clinical practice with the mercury sphygmomanometer now considered to be an environmental hazard. Manual BP is also subject to measurement error on the part of the physician/nurse and patient-related anxiety which can result in poor quality BP measurements and office-induced (white coat) ...
Flynn Joseph T - - 2012
Background: There are now numerous studies that have documented an increased risk of cardiovascular morbidity and mortality in young adults who had childhood-onset end-stage renal disease (ESRD). Since the number of such patients surviving to adulthood is increasing, strategies to reduce this risk are urgently needed. Methods: The various risk ...
Schillaci Giuseppe - - 2012
BACKGROUND: Inflammatory rheumatic diseases have been associated with increased cardiovascular risk and arterial stiffness. Polymyalgia rheumatica (PMR), a disease which affects primarily older people, is characterised by a systemic inflammatory response but little is known about aortic involvement in PMR. A study was undertaken to investigate whether aortic stiffness is ...
Karpov Yuri - - 2012
INTRODUCTION: As several international guidelines on hypertension have now recommended, singlepill/fixed-dose combination antihypertensive therapies may be particularly beneficial as firstline therapy in high-risk patients, in whom more rapid and pronounced blood pressure (BP) control is desired. Upon the single-pill combination of amlodipine and valsartan becoming available, the authors conducted this ...
Sakai Yukinao - - 2012
Background: Aliskiren, a novel direct renin inhibitor, is hypothesized to inhibit the renin-angiotensin- system. This study attempted to provide insight into this mechanism by examining the antihypertensive and renoprotective effects of aliskiren in hypertensive chronic kidney disease (CKD) patients. Methods: After recruitment, 43 hypertensive CKD patients (mean age, 53.7 years) ...
KamiƄski Grzegorz Wiktor - - 2012
Background: The impact of subclinical hyperthyroidism (sHT) on the cardiovascular system still needs to be elucidated. The aim of the study was to prospectively assess blood pressure, variability in heart rate, and the prevalence of arrhythmias in patients with sHT, both before and after they are restored to the euthyroid ...
Huang Tao - - 2012
The relationship between plasma fatty acid (FA) levels and hypertension in Chinese is not fully understood. The aim of this study was to examine relationships between plasma phospholipid (PL) FAs and hypertension in Chinese subjects. One thousand one hundred and fifty-four subjects in Hangzhou, China, were recruited in this cross-sectional ...
Chung Chang-Min - - 2012
INTRODUCTION: Arterial stiffness may contribute to left ventricular hypertrophy (LVH). This study was conducted to evaluate the independent factor of LVH and the quantification of LVH by electrocardiogram (ECG) to predict the degree of aortic stiffness using brachial-ankle pulse wave velocity (baPWV) in subjects with hypertension. MATERIALS AND METHODS: A ...
Brown David W - - 2012
BACKGROUND: Appropriate patient selection for transcatheter pulmonary valve (TPV) replacement requires accurate evaluation of right ventricular (RV) performance. The aim of this study was to evaluate the reliability and accuracy of echocardiography for evaluating RV parameters in patients in the five-center Melody TPV trial. METHODS: Echocardiographic data were compared with ...
Sullivan Jonathan G - - 2012
AIMS: Establishing accurate initial resting pressures is an important step in quality control at the start of a urodynamics test. We therefore carried out a prospective study to establish the initial resting pressures achievable with careful quality control. METHODS: Consecutive patients undergoing urodynamics were recruited. Initial resting pressures were recorded ...
Yamakado Koichiro - - 2012
PURPOSE: To evaluate the incidence and cause of hypertension prospectively during adrenal radiofrequency ablation (RFA). METHODS: For this study, approved by our institutional review board, written informed consent was obtained from all patients. Patients who received RFA for adrenal tumors (adrenal ablation) and other abdominal tumors (nonadrenal ablation) were included ...
Spruill Tanya M - - 2012
Blood pressure screening is an important component of cardiovascular disease prevention, but a hypertension diagnosis (i.e., label) can have unintended negative effects on patients' well-being. Despite persistent disparities in hypertension prevalence and outcomes, whether the impact of labeling differs by race is unknown. The purpose of this study was to ...
Pressman Gregg S - - 2012
Obstructive apneas produce high negative intrathoracic pressure that imposes an afterload burden on the left ventricle. Such episodes might produce structural changes in the left ventricle over time. Doppler echocardiograms were obtained within 2 months of attended polysomnography. Patients were grouped according to apnea-hypopnea index (AHI): mild/no obstructive sleep apnea ...
Leiter R - - 2012
BACKGROUND: /st>New ventilators have simplified the use of supraglottic superimposed high-frequency jet ventilation (SHFJV(SG)), but it has not been systematically compared with other modes of jet ventilation (JV) in humans. We sought to investigate whether SHFJV(SG) would provide more effective ventilation compared with single-frequency JV techniques. METHODS: /st>A total of ...
Motooka Tsutomu - - 2012
BACKGROUND: When standing, leg alignment is controlled by supinating or pronating the subtalar joint, corresponding to valgus or varus deformity of the knee joint. However, in the gait cycle, it is not clear whether the abnormal alignment can be compensated. OBJECTIVE: The purpose of this study was to evaluate the ...
Fang Fang - - 2012
BACKGROUND: The intervention timing in atrial septal defect (ASD) or pulmonary valvular stenosis (PVS) is more dependent on symptoms than right ventricular (RV) damage in clinical practice. RV long-axis function is sensitive in revealing RV myocardial dysfunction. We evaluate the impact of different chronic loading conditions on RV long-axis function ...
Souza Weimar Kunz Sebba Barroso - - 2012
BACKGROUND: The measurement of blood pressure (BP) by the patient himself without strict protocols, adequate training, and validated equipment at their own household is defined as self measured blood pressure (SMBP). OBJECTIVE: To evaluate the interference of the SMBP in treatment adherence and blood pressure control. METHODS: The study included ...
Nordstrand Njord - - 2012
BACKGROUND: Nocturnal hypertension, increased night-to-day systolic blood pressure (BP) ratio and nondipper status (night-to-day systolic BP ratio > 0.9) are associated with an increased risk of cardiovascular disease. Our aim was to compare the 1-year effect of Roux-en-Y gastric bypass (RYGB) vs a program of intensive lifestyle intervention (ILI) only ...
Oliveras A - - 2012
Arterial hypertension is a well-known disease with a worldwide high prevalence and impaired prognosis with respect to normotensive subjects, due to increased cardiovascular mortality and morbidity. Blood pressure levels over range can be successfully controlled with adequate treatment, but more than 10% of hypertensive people have their blood pressure uncontrolled ...
Kalmar A F - - 2012
BACKGROUND: /st>The steep (40°) Trendelenburg position optimizes surgical exposure during robotic prostatectomy. The goal of the current study was to elucidate the influence of this patient positioning on cerebral blood flow and zero flow pressure (ZFP), and to assess the validity of different methods of evaluating ZFP. METHODS: /st>In 21 ...
Bursi Francesca - - 2012
The purpose of this study was to determine among community patients with heart failure (HF) whether pulmonary artery systolic pressure (PASP) assessed by Doppler echocardiography was associated with death and improved risk prediction over established factors, using the integrated discrimination improvement and net reclassification improvement. Although several studies have focused ...
van der Linden Petra - - 2012
OBJECTIVE:: Adrenalectomy for unilateral primary aldosteronism cures hypertension in less than 50% of patients, but improvement is observed in most of the remaining ones. Our goal was to quantify the blood pressure (BP) decrease adjusted for medication changes following adrenalectomy and to identify preoperative predictors of this outcome. METHODS:: We ...
Tanindi Asli - - 2012
Objective. Red cell distribution width (RDW) which is reported as part of complete blood count in routine clinical practice, is a measure of variability in size of the erythrocytes in the circulation. It is a novel predictor of mortality both in unselected populations and in some selected group of patients. ...
Gu Guo-Qiang - - 2012
Aims. This study was designed to determine if fractional systolic/diastolic pressures act as predictors of the extent of coronary artery disease. Patients and methods. A total of 545 consecutive patients (305 men, 240 women, with mean age 54.2 years) were involved in the study. The patients were diagnosed with coronary ...
Thomson Angus J M - - 2012
STUDY OBJECTIVE: To establish whether time, pressure, or volume is the most reliable indicator of adequate pneumoperitoneum and, hence, the best parameter to use for safe trocar entry. DESIGN: Prospective cohort study (Canadian Task Force classification II-2). SETTING: Department of Endogynecology, Royal Hospital for Women, Sydney, Australia. PATIENTS: One hundred ...
Tibbetts Michael D - - 2012
A 7-year-old girl was referred for ophthalmological examination after the result of a routine school vision screening identified unilateral vision loss. Fundus examination showed bilateral but markedly asymmetric macular exudates and optic disk edema. After the results of two blood pressure measurements were within normal limits, a third markedly elevated ...
Mustafa Hossam I - - 2012
Postural tachycardia syndrome (POTS) is characterized by excessive orthostatic tachycardia and significant functional disability. We have previously found that patients with POTS have increases in plasma angiotensin II (Ang II) that are twice as high as healthy subjects despite normal blood pressures (BPs). In this study, we assess systemic and ...
Price Laura C - - 2012
Acute lung injury (ALI) and acute respiratory distress syndrome are characterized by protein rich alveolar edema, reduced lung compliance, and acute severe hypoxemia. A degree of pulmonary hypertension (PH) is also characteristic, higher levels of which are associated with increased morbidity and mortality. The increase in right ventricular (RV) afterload ...
Sameh Wael M - - 2012
OBJECTIVE: To document, in an in vivo study, the pressure transmission from the urinary bladder to the upper tract through ureteric stents in human patients. Stents have acquired special importance in the urological armamentarium. Flank pain and hydronephrosis are associated with stenting in 50% and 18% of cases, respectively. Pressure ...
Wu Han-Ping - - 2012
ObjectivesHypertensive crisis is categorised into hypertensive urgency and hypertensive emergency. The present work aimed to determine the effect of different gradings of blood pressure (BP) ratios in predicting the severity of paediatric hypertensive crisis.MethodsThis was a retrospective case series, based in the paediatric emergency departments of the Changhua Christian Hospital ...
Kumar Abhay - - 2012
BACKGROUND: Diffuse edema involving the posterior fossa may be seen with hypertensive encephalopathy and has rarely been reported to cause hydrocephalus. We present three such cases and review the literature to better delineate this uniquely reversible syndrome. METHODS: Case reports and review of literature. RESULTS: Three patients with hypertensive encephalopathy ...
Tsai Wei-Chuan - - 2012
OBJECTIVE:: Postsystolic shortening is associated with hypertensive heart disease, and the degree of postsystolic shortening can be measured by postsystolic strain index (PSI) of the left ventricle (LV) derived from speckle tracking echocardiography. We studied the association between PSI with delayed diastolic lengthening and diastolic dysfunction in hypertension. METHODS:: This ...
Krol R - - 2012
Background  Late anorectal toxicity is a frequent adverse event of external beam radiotherapy (EBRT) for prostate cancer. The pathophysiology of anorectal toxicity remains unknown, but we speculate that rectal distensibility is impaired due to fibrosis. Our goal was to determine whether EBRT induces changes of rectal distensibility as measured by ...
Yoo Byung Won - - 2012
OBJECTIVES: In correction of tetralogy of Fallot (TOF), surgical strategies to minimize right ventricular outflow tract (RVOT) enlargement have recently been preferred. However, we may be confronted with residual pulmonary stenosis (PS) combined with pulmonary regurgitation (PR), and how the pressure load affects these patients is not evident. METHODS: We ...
Rangan A M - - 2012
BACKGROUND/OBJECTIVES:It has been postulated that a higher dairy consumption may affect blood pressure regulation. The aim of this study was to examine the association between dairy consumption and blood pressure in mid-childhood.SUBJECTS/METHODS:Subjects (n=335) were participants of a birth cohort at high risk of asthma with information on diet at 18 ...
Meng Lingzhong L Department of Anesthesiology & Perioperative Care, University of California Irvine Medical Center, 101 The City Drive South, Bldg. 53, Rm. 227, Orange, CA 92868, USA. - - 2012
During anesthesia, maneuvers which cause the least disturbance of cerebral oxygenation with the greatest decrease in intracranial pressure would be most beneficial to patients with intracranial hypertension. Both head-up tilt (HUT) and hyperventilation are used to decrease brain bulk, and both may be associated with decreases in cerebral oxygenation. In ...
Worsøe J - - 2012
Background:Constipation and fecal incontinence are considerable problems for most individuals with spinal cord injury (SCI). Neurogenic bowel symptoms are caused by several factors including abnormal rectal wall properties. Stimulation of the dorsal genital nerve (DGN) can inhibit bladder contractions and because of common innervation inhibitory effects are anticipated in the ...
Abd El Dayem Soha M - - 2012
OBJECTIVE: To estimate the influence of body composition and body mass index on blood pressure in type 1 diabetic patients. METHODS: This cross-sectional, observational study included 45 type 1 diabetic patients and 30 age and sex matched healthy volunteers. Blood pressure, anthropometric measurements, and body composition by dual X-ray absorptiometry ...
Gomez-Laberge C - - 2012
Patients with acute lung injury or acute respiratory distress syndrome (ALI/ARDS) are vulnerable to ventilatorinduced lung injury. Although this syndrome affects the lung heterogeneously, mechanical ventilation is not guided by regional indicators of potential lung injury. We used electrical impedance tomography (EIT) to estimate the extent of regional lung overdistension ...
Hoshino Masato - - 2012
INTRODUCTION: There has been an increase in the number of patients seeking treatment after an anti-reflux surgical procedure. The objective of this study is to describe high-resolution manometry (HRM) topography as it relates to the post-fundoplication anatomy. METHODS: Retrospective review of a prospectively maintained database was conducted to identify patients ...
Bhatia Sonal - - 2012
"Hypertensive" variant of congenital adrenal hyperplasia is rare. The authors describe an interesting case of a 6-y-old boy who presented with an acute respiratory illness and progressive breathlessness since 1 y. Genital hyperpigmentation was noticed since 2 y of age; the onset of pubarche and increasing penile size at 4 y. He was ...
Leatherman James W - - 2012
BACKGROUND: Expiratory muscle activity may cause the end-expiratory central venous pressure (CVP) to greatly overestimate right atrial transmural pressure. METHODS: We recorded CVP and expiratory change in intra-abdominal pressure (ΔIAP) in 39 patients who had a respiratory excursion in CVP from end-expiration to end-inspiration (CVP(ee)-CVP(ei)) ≥8 mmHg. Uncorrected CVP was measured at ...
Mortensen Kristian Havmand - - 2012
Objective:  Carotid intima-media thickness (IMT) may potentially supplement cardiovascular risk assessment in Turner syndrome (TS), where cardiovascular risk is high and appropriate risk stratification difficult. Knowledge of intima-media thickness in TS is scarce, and this study aimed to enhance insight into the cardiovascular risk marker. Design, Patients and Measurements:  IMT ...
Fujiwara M - - 2012
Objectives: The aim of this study was to report the long-term outcome of the surgical palliation of pulmonic stenosis in dogs. Methods: The subjects comprised three female and six male dogs, mean (±sd) age: 23 (±25) months, mean (±sd) weight: 3·4 (±2·1) kg, diagnosed with severe pulmonic stenosis and right ...
Ertas Faruk - - 2012
Objective. Epicardial fat has been proposed as a new cardiometabolic risk factor. Although epicardial fat thickness (EFT) is associated with hypertension, the relationship between diurnal blood pressure profiles and EFT is still unknown. The purpose of this study is to investigate the association between the echocardiographic EFT and diurnal blood ...
Rosenbaum David - - 2012
Twenty-four-hour ambulatory blood pressure monitoring (ABPM) has been shown to be more reliable than conventional measurements for hypertension assessment and the associated increased risk of cardiovascular events. Olmesartan/hydrochlorothiazide combination therapy has demonstrated increased blood pressure lowering over 24 hours compared with the component monotherapies. This prespecified pooled analysis of data ...
Peralta Carmen A CA Department of Medicine, San Francisco VA Medical Center, San Francisco, California, USA. - - 2012
Treatment of hypertension is difficult in chronic kidney disease (CKD), and blood pressure goals remain controversial. The association between each blood pressure component and end-stage renal disease (ESRD) risk is less well known. We studied associations of systolic and diastolic blood pressure (SBP and DBP, respectively) and pulse pressure (PP) ...
Fontana Vanessa - - 2012
Growing experimental evidence indicates that matrix metalloproteinases (MMPs) are implicated in many cardiovascular diseases including hypertension and its chronic complications. It is now clear that MMPs have many more substrates other than components of the extracellular matrix. In fact, intracellular targets now include those associated with the cardiovascular system. Clinical ...
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