Catecholamine-associated cardiomyopathies caused by neuroblastoma have rarely been reported. We are reporting 2 cases of neuroblastoma associated with hypertension and severe cardiomyopathic changes in different extremes. One case was dilated cardiomyopathy with heart failure, and the other showed echocardiographic features simulating hypertrophic obstructive cardiomyopathy. Both girls had high levels of ...

Thermodynamic stability boundary of structure-H hydrates with large guest species and methane (CH4) at extremely high pressures has been almost unclear. In the present study, the four-phase equilibrium relations in the structure-H CH4+1,1,2,2,3,3,4-heptafluorocyclopentane (1,1,2,2,3,3,4-HFCP) mixed hydrate system were investigated in a temperature range of (281.05 to 330.12) K and a ...

The magnetic properties of [Fe(III)Cp*2]˙(+)[HCBD]˙(-) (Cp* = pentamethylcyclopentadienide; HCBD = hexacyanobutadienide, C4(CN)6) and [Fe(III)Cp*2]˙(+)[DDQ]˙(-) (DDQ = 2,3-dichloro-5,6-dicyanoquinonide) were measured at ambient and applied hydrostatic pressures up to 11.4 and 9.2 kbar, respectively. At ambient pressure [FeCp*2][HCBD] exhibits spin glass-like behavior with a freezing temperature, Tf, of 2.93 K from the ...

Diffuse optical tomography (DOT) is an emerging oncological imaging modality that is based on a near-infrared optical technique. DOT provides the spatial volume and depth of tumors by determination of optical properties of biological tissues, such as the absorption and scattering coefficients. During a DOT, the optical fibers are kept ...

The magnetic symmetry and structure of the non-Fermi liquid heavy fermion compound CeNiGa2 has been determined by neutron powder diffraction. The orthorhombic CeNiGa2 compound orders antiferromagnetically below 4.4(2) K at ambient pressure with a magnetic moment magnitude of μCe = 0.80(4) μB for moments aligned along the c-axis. The magnetic (Shubnikov) space group is ...

The pressure dependence of the magnetic properties of ferrimagnetic Mn(II)(TCNE)I(OH2) up to 14.05 kbar and Mn(II)(TCNE)3/2(I3)1/2·zTHF up to 14.32 kbar were studied. For Mn(II)(TCNE)I(OH2), two distinct pressure regions separated at ∼1 kbar were evident in both the temperature and the field-dependent magnetic measurements. No increase of the magnetic properties was ...

RATIONALE AND OBJECTIVES: The end point of chemoembolization for hepatocellular carcinoma is qualitative. We intended to determine the feasibility of measuring intra-arterial pressure changes after chemoembolization and hypothesized that pressures would increase in the distal hepatic artery after the procedure. MATERIALS AND METHODS: Before and after chemoembolization, systemic (S) systolic ...

Tumor necrosis factor α (TNFα) is a pleiotropic cytokine which becomes elevated in chronic inflammatory states such as hypertension and diabetes and has been found to mediate both increases and decreases in blood pressure. High levels of TNFα decrease blood pressure, whereas moderate increases in TNFα have been associated with ...

In the prototypical heavy-fermion system CeCu_{6-x}Au_{x}, a magnetic quantum critical point can be tuned by Au concentration x, hydrostatic pressure p, or magnetic field B. A striking equivalence of the tuning behavior with x or p had been found with respect to thermodynamic and transport properties. By means of elastic ...

We report a combined study using magnetization and Raman spectroscopy on the magnetic ionic liquid 1-ethyl-3-methylimidazolium tetrachloroferrate, Emim[FeCl4]. This material shows a long-range antiferromagnetic ordering below the Néel temperature TN ≈ 3.8 K. The effects of pressure on the magnetic properties have been studied using a miniature piston-cylinder CuBe pressure ...

We have studied the pressure-induced phase transitions from NaCl-type (B1) to CsCl-type (B2) structure in BaS, BaSe and BaTe by using ab initio density functional theory computations in the local density approximation. The Buerger and WTM mechanisms were explored by mapping the enthalpy contours in two- and four-dimensional configuration space ...

Swallowing disturbances are common after neurological disease and oropharyngeal tumor resection. In this case the oral stage is often affected. So far the clinical evaluation of the oral phase is limited. Recently the role of pressure changes during oropharyngeal swallowing has been pointed out, but until now there are not ...

Hypertension ranks among the most important disease challenges on a global scale. Here, a novel hypothesis is presented which implicates angiotensinogen, i.e. the precursor protein for the hypertensive peptide angiotensin II, as a key culprit in the pathogenesis of hypertension. This hypothesis more precisely entails that intracellular angiotensinogen binds and ...

We report unprecedented dramatic changes in the 647.1 nm Raman signal of PbZr(0.6)Ti(0.4)O(3) occurring in the same pressure ranges as the critical pressures of the antiferrodistortive and ferroelectric-paraelectric phase transitions. This huge decrease in intensity of both the Raman modes and the background, observed for both pressure transmitting media used ...

Diamond-anvil cell, pressure-tuning infrared (IR), and Raman microspectroscopic measurements have been undertaken to examine the effects of high pressures up to about 45 kbar on the vibrational spectra of the four DNA bases, adenine, cytosine, guanine, and thymine. Small structural changes were evident for all the four bases, viz., for adenine ...

The high-pressure crystal structures of the "111" type iron-based superconductors: NaFeAs, LiFeP and LiFeAs have been systematically explored by using particle-swarm structural searches. It was found that though these iron-based superconductors are chemically similar, they adopted distinct structural phase transitions: P4/nmm → Cmcm → P3[combining macron]m1 for NaFeAs, P4/nmm → ...

Topical protoporphyrin (PpIX)-induced photodynamic therapy (PDT) relies on the penetration of the prodrug into the skin lesion and subsequent accumulation of the photosensitizer. Methyl aminolevulinate (MAL)-PDT is an established treatment for thinner and superficial non-melanoma skin cancers (NMSCs) but for the treatment of the thicker nodular basal cell carcinoma (nBCC) ...

Transcranial ultrasound improves thrombolytic drug efficacy in ischemic stroke therapy. The goal of this study was to determine the ideal ultrasound parameters for obtaining peak rarefactional pressures exceeding the stable cavitation threshold at the left anterior clinoid process (lACP) of the skull. This location is near the origin of the ...

Standard cardiorespiratory monitoring may fail to detect occult tissue ischaemia. This study assessed whether a near infra-red spectroscopy tissue oxygen saturation monitor (InSpectra™) could detect progressive peripheral tissue ischaemia and whether hyperoxia may confound tissue oxygen saturation measurement. Tissue oxygen and arterial oxygen saturations were measured continuously in 30 healthy ...

BACKGROUND: /st>Muscular compartment syndrome (MCS) is a rare but serious postoperative complication. In vivo optical spectroscopy (INVOS) monitors continuously and non-invasively regional oxygen saturation (rSO(2)), and could predict the development of MCS. METHODS: /st>In 10 healthy volunteers, we inflated a tourniquet to the mean arterial pressure to produce slight venous ...

Objective: To evaluate the short-term impact of intravitreal ranibizumab injection on axial ocular dimension (AOD) and intraocular pressure (IOP). Methods: A total of 31 patients who received 0.05 mL intravitreal ranibizumab injection (IRI) for age-related macular degeneration and 30 healthy volunteers were enrolled in the study. AODs i.e. anterior chamber depth ...

Low pressure headache typically occurs as a complication of dural puncture. "Spontaneous" low pressure headache is a relatively rare but under-recognised cause of intractable headache. Clinical suspicion of this condition warrants imaging of the brain to confirm the diagnosis; spinal imaging may be needed to identify the site of the ...

Tissue oedema plays an important role in the pathology of chronic and traumatic wounds. Negative pressure wound therapy (NPWT) is thought to contribute to active oedema reduction yet few studies have showed this effect. In this study high frequency diagnostic ultrasound at 20 MHz with an axial resolution of 60 ...

The recently advanced hypothesis that idiopathic intracranial hypertension without papilledema (IIHWOP) is a powerful risk factor for the progression of pain in individuals prone to episodic primary headache implies that IIHWOP is much more prevalent than it is believed to be in the general population and that it can run ...

Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with high morbidity and mortality. Acutely, ICH is associated with a sudden surge in intracranial pressure (ICP), as the volume of hematoma increases the pressure in the closed head, leading to non-specific symptoms of ICP: headache, nausea, vomiting, and alterations in consciousness. ...

Noninvasive image-based measurement of intrinsic tissue pressure is of great interest in the diagnosis and characterization of diseases. Therefore, we propose to exploit the capability of phase-contrast MRI to measure three-dimensional vector fields of tissue motion for deriving volumetric strain induced by external vibration. Volumetric strain as given by the ...

BACKGROUND AND IMPORTANCE: Epidural blood patch (EBP) is one therapeutic measure for patients suffering from spontaneous intracranial hypotension (SIH) or post-lumbar puncture headaches. It has been proposed that an EBP may directly seal a spinal cerebrospinal fluid (CSF) fistula or result in an increase in intracranial pressure (ICP) by a ...

Aortic cross clamping is associated with spinal cord ischemia. This study used a rat spinal cord ischemia model to investigate the effect of distal aortic pressure on spinal cord perfusion. Male Sprague-Dawley rats (n=12) were divided into three groups. In group A (n=4), the aorta was not occluded. In groups ...

The high hydrostatic pressure effect on the magnetic properties of the layered hybrid compounds Cu(2)(OH)(3)(C(n)H(2n+1)CO(2))⋅mH(2)O with distance between magnetic layers of up to 40 Å is studied. It is shown that the temperature of the ferromagnetic ordering decreases linearly with pressure increase. From measurements of susceptibility in the paramagnetic region, using both ...

Idiopathic intracranial hypertension is a headache syndrome characterized by elevated intracranial pressure with normal cerebrospinal fluid content, normal cranial imaging, and elevated appearance of the optic disc. We report on a 6.5-year-old boy with complaints of headache and right esotropia causing diplopia. A lumbar puncture indicated an opening cerebrospinal fluid ...

In 2007, the Tissue Viability Society defined tissue viability as: 'A growing speciality that primarily considers all aspects of skin and soft tissue wounds including acute surgical wounds, pressure ulcers and all forms of leg ulceration. However, it is not just wound management, it also covers a wide range of ...

Syrinxes are fluid-filled cavities of the spinal cord that characterize syringomyelia, a disease involving neurological damage. Their formation and expansion is poorly understood, which has hindered successful treatment. Syrinx cavities are hydraulically connected with the spinal subarachnoid space (SSS) enveloping the spinal cord via the cord interstitium and the network ...

Recent genomewide association studies of large samples have identified genes that are associated with blood pressure. The Global Blood Pressure Genetics (Global BPgen) and Cohorts for Heart and Aging Research in Genome Epidemiology (CHARGE) consortiums identified 14 loci that govern blood pressure on a genomewide significance level, one of which ...

Pressure mapping alone insufficiently describes tissue health. Comprehensive, quantitative non invasive assessment is crucial. Interface pressures (IPs) and transcutaneous blood gas levels [transcutaneous tissue oxygen (T(c) PO(2) )] were simultaneously assessed over both ischia and the sacrum to investigate the hypotheses: (i) tissue oxygenation decreases with sustained applied pressure; (ii) ...

In long-term prevention and in rehabilitation of health of elderly people the recording of vital signs plays an important role. Especially the progress of rehabilitation can be deduced from the recording of an electrocardigram (ECG), blood pressure and body temperature. In this paper we present a wireless coupled recording device ...

Despite substantial advances in orthopaedic surgery, bone nonunion is still a matter of debate for orthopaedic surgeon to provide optimal options on treatment of nonunion. Negative pressure therapy has already been successfully used in dealing with complex kinds of soft tissue healing. Some studies show that negative pressure can induce ...

Objectives:  To assess the clinical efficacy of the self-pressurized air-Q ILA™ (ILA-SP). Aim:  The purpose of this prospective audit was to evaluate the feasibility of the ILA-SP in clinical practice and generate data for future comparison trials. Background:  The ILA-SP is a new first-generation supraglottic airway for children with a ...

PURPOSE: Right ventricular systolic pressure is crucial for both treatment and prognosis of cardiovascular and pulmonary diseases. The proper measurement of right ventricular systolic pressure depends on an accurate estimation of right atrial pressure (RAP). There is no standard method for estimating RAP noninvasively. The purpose of this study was ...

The insertion of an epidural catheter for labour analgesia may be challenging. This observational study compared pressures during insertion of an epidural catheter in pregnant (n = 35) and non-pregnant (n = 10) women, using an acoustic device for locating the epidural space that also records and stores pressure data during the ...

Objective  The purpose of this study was to investigate the effect of extubation with the endotracheal tube (ETT) cuff inflated versus deflated on endotracheal fluid volume in normal canine cadavers. Study Design  Prospective randomized blinded controlled cadaver study. Animals  Sixteen adult Beagle cadavers weighing 10.7 ± 1.7 kg (mean ± SD) and <2 years of age. ...

Documentation of femoral head blood flow before, during and after head preserving surgery is important for safeguarding vascularity to the femoral head and for documentation in patients in whom the blood flow is compromised. Laser Doppler flowmetry and microsensor intracranial pressure (ICP) transducers have been used to satisfactorily depict such ...

Background: There are reports in the literature regarding the effects of hyperbaric conditions on various medical devices. In the current study we evaluated the performance of an elastomeric infusion device during exposure to a hyperbaric environment. Methods: Nineteen disposable 400-mL On-Q pain ball infusion devices were filled with 0.2% ropivacaine ...

It is recommended to maintain cuff pressure (CP) within a defined range of 20 to 30 cm H₂O. Excessive cuff inflation is a recognized risk factor for tracheal injury and stenosis. Insufficient CP can increase the leakage of colonized sub-glottic secretions above the cuff, contribute to air leak, and increase ...

BACKGROUND: The high-volume low-pressure tracheal tube cuffs always form folds upon inflation in the trachea, allowing the passage of heavily colonized mucus into the lungs. METHODS: We designed and developed an elastic, thin-walled prototype endotracheal tracheal tube cuff made of Lycra. In-vitro study: we tested the new prototype cuff, the ...

We studied the effect of incremental infusion of fluid volume in a tamponade balloon on intraluminal pressure and uterine blood flow. Following placental delivery, a tamponade balloon was inserted into the uterus and incrementally inflated. Intraluminal pressure was measured at incremental volumes. Ultrasound was used to determine positioning of the ...

OBJECTIVES:: Tracheal mucosal perfusion is compromised at an endotracheal tube (ETT) cuff pressure of 30 cm H2O, and blood flow is obstructed at a pressure of 50 cm H2O. METHODS:: We measured the change in pressure of air-filled cuffs of 6.0 and 7.5 ETTs and a size 4 laryngeal mask ...

BACKGROUND:: Epidural analgesia can result in perioperative hypotension in patients having thoracotomy. This randomized prospective study assessed the effects of epidural and paravertebral analgesia on hemodynamics during thoracotomy. METHODS:: Thirty-two patients were randomized to receive either epidural analgesia (n = 16, 0.25% levobupivacaine and 30 μg/kg morphine) or paravertebral block ...

Non-invasive and immediate estimation of left atrial pressure (LAP) is very useful for the management of mitral regurgitation (MR), and many reports have assessed echocardiographic estimations of LAP to date. However, it has been unclear of which examination and evaluate article possess the best accuracy for the MR severity. The ...

STUDY OBJECTIVE: To investigate intracuff pressure changes in the ProSeal Laryngeal Mask Airway (PLMA) during 50% nitrous oxide (N(2)O) anesthesia. DESIGN: Prospective, randomized study. SETTING: Operating room of a university-affiliated hospital. PATIENTS: 40 ASA 1 and 2 children, aged 2 to 6 years, weighing 10-20 kg, undergoing elective inguinal herniorrhaphy ...

Background:  Most patients affected with Duchenne muscular dystrophy (DMD) present with arrhythmias and cardiomyopathies. Drugs which potentially may induce tachycardia or hypertension could precipitate acute cardiac failure in these patients and should be avoided. Methods:  Thirty anesthesia records of five experimental male golden retriever cross-bred dogs affected with X-linked muscular ...