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Valente Pedro Miguel Ds PM Australian School of Advanced Medicine, Macquarie University, Sydney, NSW, - - 2014
Chronic wounds remain a significant medical and financial burden in hospitals of today. A major factor in the transition from an acute to a chronic wound is its bacterial bioburden. Developments in molecular techniques have shown that chronic wounds remain colonised by many species of bacteria and that the bacteria ...
Cook Saranne J SJ Orthopaedic Research Laboratory, University of Utah Orthopaedic Center, Salt Lake City, UT 84108, USA; Bone and Joint Research Laboratory, Department of Veterans Affairs Medical Center, Salt Lake City, UT 84148, - - 2014
Long-term maintenance of a dermal barrier around a percutaneous prosthetic device remains a common clinical problem. A technique known as Negative Pressure Wound Therapy (NPWT) uses negative pressure to facilitate healing of impaired and complex soft tissue wounds. However, the combination of using negative pressure with percutaneous prosthetic devices has ...
Kim Paul J PJ Washington, D.C.; and Dallas, Texas From the Department of Plastic Surgery, Georgetown University Hospital; Georgetown University School of Medicine; Georgetown University Medical Center; and the Department of Plastic Surgery, University of Texas Southwestern Medical - - 2014
Negative-pressure wound therapy with instillation is a novel wound therapy that combines negative pressure with instillation of a topical solution. This retrospective, historical, cohort-control study examined the impact of negative-pressure wound therapy with and without instillation. One hundred forty-two patients (negative-pressure wound therapy, n = 74; therapy with instillation, 6-minute ...
Wagstaff Marcus James Dermot MJ Department of Plastic and Reconstructive Surgery, Royal Adelaide Hospital, Adelaide, South Australia, - - 2014
The objectives of the study were (1) to look for any local, clinically apparent response, within and around a debrided wound, to a novel biocompatible polyurethane foam during repeated, short-term implantation, and (2) to assess the material's efficacy as a negative pressure wound therapy (NPWT) interface compared with a widely ...
Fouilland Eric - - 2014
The effects of grazing pressure and inorganic nutrient availability on the direct carbon transfer from freshly produced phytoplankton exudates to heterotrophic bacteria biomass production were studied in Mediterranean coastal waters. The short-term incorporation of ¹³C (H¹³CO₃) in phytoplankton and bacterial lipid biomarkers was measured as well as the total bacterial ...
Olona Carles C Carles Olona, PhD, is a Surgeon Specialist; and Enric Duque, MD, is a Resident at the General and Digestive Surgery Department, Joan XXIII University Hospital, Tarragona, Spain. Aleidis Caro, PhD, is a Surgeon Specialist at the General and Digestive Surgery Department, Parc Taulí University Hospital, Sabadell, Spain. Andrea Jiménez, MD, is a Surgeon Specialist at the General and Digestive Surgery Department, Joan XXIII University Hospital, Tarragona, Spain. Félix Moreno, MD, is a Resident at the General and Digestive Surgery Department, Joan XXIII University Hospital, Tarragona, Spain. Jose M. Coronas, MD, is a Surgeon Specialist at the General and Digestive Surgery Department, Joan XXIII University Hospital, Tarragona, Spain. Vicente Vicente, PhD, is Head of the General and Digestive Surgery Department, Joan XXIII University Hospital, Tarragona, - - 2014
Negative pressure therapy has proven useful in the treatment of the complex complications of surgical wounds. In this pilot study, the authors found that the negative pressure system can be used safely in the postoperative period of incisional hernia surgery and reduces the number of days of drainage.
Ye Mu M Department of Animal & Food Sciences, University of Delaware, Newark, DE - - 2014
Human norovirus (NoV) is the most frequent causative agent of foodborne disease associated with shellfish consumption. In this study, the effect of high-hydrostatic pressure (HHP) on inactivation of NoV was determined. Genogroup I.1 (GI.1) or Genogroup II.4 (GII.4) NoV were inoculated into oyster homogenates and treated at 300-600 MPa at ...
Altintas Burak B Department of Trauma and Orthopedic Surgery, Klinikum Nuernberg, Nuernberg, - - 2014
Negative pressure wound therapy has been lately used on closed incisions in the immediate postoperative period to accelerate wound healing. However, there are no data in the literature regarding the use of this type of therapy for wounds with persistent secretion in the early postoperative care. We present the first ...
Wang Xingang X Department of Burns & Wound Care Centre, Second Affiliated Hospital of Zhejiang University, Hangzhou, China - - 2014
The one-step surgical procedure for dermal substitutes combined with topical negative pressure (TNP) has proven effective for treating deep skin defects with improved graft take. The primary mechanism by which TNP improves autograft take is unknown. Some studies suggest that TNP promotes the rapid angiogenesis of dermal substitutes, improving graft ...
Zygner W - - 2014
Acute tubular necrosis (ATN) was described in canine babesiosis. Hypotension is considered as one of the factors which influence the development of hypoxic renal damage. In this study hypotension defined as mean arterial pressure (MAP) < 80 mmHg was detected in 7 out of 48 dogs (14.6%) infected with Babesia ...
Malmsjö Malin M Clinical Sciences, Lund, Lund University and Skåne University Hospital, Lund, - - 2014
Objective: Recent developments of negative pressure wound therapy (NPWT) systems have focused on making pumps smaller, lighter, and more portable. The recently introduced PICO system manages wound fluid through a highly breathable film within the dressing, thereby negating the need for a canister, which allows greater mobility and patient concordance. ...
Pluznick Jennifer J Department of Physiology; Johns Hopkins University School of Medicine; Baltimore, MD - - 2013
The maintenance of blood pressure homeostasis is a complex process which is carefully regulated by a variety of inputs. We recently identified two sensory receptors (Olfactory receptor 78 and G protein couple receptor 41) as novel regulators of blood pressure. Both Olfr78 and Gpr41 are receptors for short chain fatty ...
Asher Scott A SA Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, School of Medicine at the University of Alabama at Birmingham, - - 2013
IMPORTANCE Negative pressure wound therapy has been shown to accelerate healing. There is a paucity of literature reporting its use as a tool to promote wound healing in head and neck reconstruction. OBJECTIVE To review 1 institution's experience with negative pressure dressings to further describe the indications, safety, and efficacy ...
Kim Se Ik SI Center for Uterine Cancer, Research Institute and Hospital, National Cancer Center, Gyeonggi-do, Republic of Korea; Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of - - 2013
To evaluate the surgical outcome of a subcutaneous negative pressure drain without subcutaneous suture on wound healing in women undergoing abdominal gynecologic surgery. The medical records of total 322 patients who underwent abdominal surgery, including cytoreductive surgery for ovarian cancer, between March 2010 and January 2013 were reviewed retrospectively. Patients ...
Phillips Priscilla L - - 2013
Negative pressure wound therapy with instillation (NPWTi) is increasingly used as an adjunct therapy for a wide variety of infected wounds. However, the effect of NPWTi on mature biofilm in wounds has not been determined. This study assessed the effects of NPWTi using saline or various antimicrobial solutions on mature ...
Rycerz Anthony M - - 2013
A new method (V.A.C.ULTA™ Therapy System, KCI USA, Inc., San Antonio, TX) combines the benefits of negative pressure wound therapy (NPWT; V.A.C.® Therapy, KCI USA, Inc.) with regulated, periodic instillation of user-selected topical wound solutions (V.A.C. VeraFlo™ Therapy, KCI USA, Inc.). In simulated wound model studies comparing solution distribution using ...
Karr Jeffrey C - - 2013
A 20-patient case series is presented, demonstrating the incorporation of a silver antimicrobial negative-pressure dressing and a negative-pressure wound therapy device for improved healing outcomes, decreased nursing time expenditure, and decreased cost expenditure.
Cushing Carolyn A - - 2013
After studying this article, the participant should be able to: 1. Cite risk factors for pressure sore development. 2. Detail the pathophysiology of pressure sores. 3. List the types and classification of pressure sores. 4. Consider the various nonsurgical conservative wound management strategies. 5. Describe the appropriate surgical interventions for ...
Lavery Lawrence A - - 2013
This study was designed to compare two approaches to negative pressure wound therapy: 125 mm Hg pressure with a polyurethane foam dressing (NPWT125) and 75 mm Hg pressure with a silicone-coated dressing (NPWT75). Forty patients with diabetic foot wounds, after incision and drainage or amputation for infection, were randomly assigned ...
Dumville Jo C - - 2013
Foot wounds in people with diabetes mellitus (DM) are a common and serious global health issue. Negative pressure wound therapy can be used to treat these wounds and a clear and current overview of current evidence is required to facilitate decision-making regarding its use. To assess the effects of negative ...
Barochia Amisha V AV National Heart, Lung and Blood Institute, National Institutes of Health, Building 10, Room 2C145, Bethesda, MD, 20892, USA, - - 2013
The Surviving Sepsis Campaign (SSC) sepsis care bundles have recently been revised. The original 6-h resuscitation bundle which included rapid antibiotic administration and hemodynamic support with early goal-directed therapy (EGDT) has been divided into two bundles; one including antibiotic and fluid support to be completed within 3 h, and the other ...
Bulla Antonio - - 2013
Negative-pressure therapy is widely applied to treat lower limb trauma.However, sealing a negative pressure dressing in the presence of an external fixation device may be difficult and time-consuming. Therefore, screws, pins, wires, etc. may preclude the vacuum, preventing the plastic drape to perfectly adhere to the foam. In order to ...
Mark Katrina S - - 2013
Objective. We sought to evaluate the efficacy of incisional negative pressure therapy in decreasing postoperative wound complications when placed prophylactically over clean, closed incisions following cesarean section in obese patients. Study design. This was a retrospective cohort study comparing rates of wound complications following cesarean sections in morbidly obese women ...
Caillier Christophe - - 2013
To minimize parasitic doping effects caused by uncontrolled material adsorption, graphene is often investigated under vacuum. Here we report an entirely unexpected phenomenon occurring in vacuum systems, namely strong n-doping of graphene due to chemical species generated by common ion high-vacuum gauges. The effect-reversible upon exposing graphene to air-is significant, ...
Kim Paul J - - 2013
Negative pressure wound therapy with instillation (NPWTi) is increasingly utilized as an adjunct therapy for a wide variety of wounds. Despite its growing popularity, there is a paucity of evidence and lack of guidance to provide effective use of this therapy. A panel of experts was convened to provide guidance ...
Marinovic Marin - - 2013
High pressure injection injuries (HPII) of the foot are not common in every-day practice. We present a 50-year-old patient with a HPII of the left foot caused by water-gun in a self-inflicted accident working as a technical diver four meters under the sea surface. Surgical treatment included extensive debridement of ...
Chuangsuwanich Apirag - - 2013
The treatment of pressure ulcers is complicated, given the various wound dressing products available. The cost of different treatments varies and the cost-effectiveness of each product has not been thoroughly evaluated. We compare two wound dressing protocols-alginate silver dressing (AlSD) and silver zinc sulfadiazine cream (AgZnSD) with regard to wound ...
Cheong Yong-Kyu - - 2013
In this study, we investigated the therapeutic potential of regulated negative pressure vacuum-assisted wound therapy for inguinal lymphatic complications in critically ill, liver transplant recipients. The great saphenous vein was harvested for hepatic vein reconstruction during liver transplantation in 599 living-donor liver transplant recipients. Fourteen of the recipients (2.3%) developed ...
Alshraiedeh Nid'a H - - 2013
The main aim of this study was to determine the inactivation virucidal efficacy of an in-house designed atmospheric pressure, non-thermal plasma jet operated at varying helium/oxygen feed gas concentrations against MS2 bacteriophage, widely employed as a convenient surrogate for human norovirus. The effect of variation of percentage oxygen concentration in ...
Davis Kathryn E - - 2013
The purpose of this study was to compare two negative-pressure wound healing systems (NPWT), -75 mmHg with a silicone-coated (SC) dressing and -125 mmHg with polyurethane foam dressing (standard of care). In addition, this study compared the effects of two different dressing interfaces, SC dressing and gauze, with -75 mmHg pressure. For both ...
Yusuf Erlangga - - 2013
No earlier study has investigated the microbiology of negative pressure wound therapy (NPWT) foam using a standardized manner. The purpose of this study is to investigate the bacterial load and microbiological dynamics in NPWT foam removed from chronic wounds (>3 months). To determine the bacterial load, a standardized size of ...
Sachsenmaier Saskia - - 2013
V.A.C.(®) GranuFoam™ therapy is regularly used in the surgical therapy of infected wounds and soft tissue injuries. Silver nanoparticles can destroy bacterial cell walls and inhibit enzymes for cell replication. Silver dressings are therefore successfully used for many indications in wound therapy. In this study, we investigated the antimicrobial potency ...
Milcheski Dimas André - - 2013
To review the experience (2011 and 2012) of Wound Center of Plastic Surgery Service, Clinics Hospital, Faculty of Medicine, University of São Paulo, with treatment of complex traumatic wounds in the perineal region with the association of negative pressure wound therapy followed by a surgical skin coverage procedure. This was ...
Hedley J - - 2013
A 42-year-old female Testudo graeca was referred with a five-month history of a non-healing carapacial wound. Previous treatment had involved long-term antibiotic therapy and conscious debridement of necrotic tissue. On presentation an extensive deep wound with purulent discharge was visible on the right side of the carapace. A computed tomographic ...
Shin Hainsworth Y - - 2013
Failure of soft tissue implants has been largely attributed to the influence of biomaterial surface properties on the foreign body response, but some implant complications, e.g. macrophage accumulation and necrosis, are still not effectively addressed with surface treatments to minimize deleterious biomaterial effects. We explored an alternative explanation for implant ...
de Souza Ancelmo Rabelo - - 2013
Mycobacterium abscessus is an important hospital-acquired pathogen involved in infections associated with medical, surgical, and biopharmaceutical materials. In this work, we investigated the pressure-induced inactivation of two strains [2544 and American Type Culture Collection (ATCC) 19977] of M. abscessus in combination with different temperatures and pH conditions. For strain 2544, ...
Sano Hitomi - - 2013
This study investigated the role of nitric oxide (NO) in the mechanism of blood flow increase in the wound bed during negative pressure wound therapy (NPWT). We developed an improved experimental model that allowed visualisation of the wound bed microcirculation under NPWT. Wounds were created on the mouse ear, taking ...
Black Joyce - - 2013
Medical device related pressure ulcers (MDR PUs) are defined as pressure injuries associated with the use of devices applied for diagnostic or therapeutic purposes wherein the PU that develops has the same configuration as the device. Many institutions have reduced the incidence of traditional PUs (sacral, buttock and heel) and ...
Kairinos Nicolas - - 2013
BACKGROUND: Although recent work has demonstrated that perfusion adjacent to a negative-pressure wound therapy (NPWT) dressing is decreased, laser Doppler studies have indicated that there is a zone of increased perfusion a couple of centimetres away. The existence of such a zone of increase perfusion is counterintuitive to the fact ...
Sano Hitomi - - 2013
Abstract A continuous irrigation with intermittent aspiration (CIIA) method has previously been developed in the treatment of infected expander sites. For the purpose of treatment of infected wounds, a new intermittent negative pressure irrigation treatment (INPIT) has been developed that is a combination of CIIA with topical negative-pressure therapy. This ...
Shah Ajul - - 2013
The advent of the negative pressure wound therapy (NPWT) has been a significant advancement in wound-healing practices. However, as the therapy has gained popularity and increased usage in all areas of the body, obstacles have arisen. In certain areas of the body, namely those with crevices and folds, or an ...
Morinaga Keigo - - 2013
Abstract Intra-wound continuous negative pressure irrigation treatment (IW-CONPIT) was administered to cases of mediastinitis as the therapy of choice, with satisfactory results being obtained in terms of improved survival rates and quick healing of wounds. Accordingly, these treatment results and efficacy were evaluated. After debridement, a sponge was trimmed to ...
Aliano Kristen A - - 2013
The heel is a common site of pressure ulcers. The amount of pressure and time needed to develop these wounds is dependent on various factors including pressure surface, the patient's anatomy, and co-morbidities. We studied the use of the hemoglobin saturation ratio as a means of assessing heel perfusion in ...
Georgakarakos Efstratios - - 2013
Negative pressure wound therapy has been increasingly used either as a primary or as an adjunctive therapeutic measure to treat a variety of recalcitrant wounds during the past years. It is thought to act by creating a local environment that promotes cell proliferation, angiogenesis, and granulation tissue formation, leading to ...
Thomas David R - - 2013
Pressure ulcers are chronic and difficult to heal. Pressure-reducing devices are clearly superior to a standard hospital mattress in preventing pressure ulcers, but only limited evidence and clinical intuition supports pressure-reducing devices in improving the healing rate of pressure ulcers. Local wound treatment should aim at maintaining a moist wound ...
Comte S - - 2013
In Europe, most cities are currently colonized by red foxes (Vulpes vulpes), which are considered to be the main definitive host of the zoonotic cestode Echinococcus multilocularis. The risk of transmission to humans is of particular concern where high fox populations overlap with high human populations. The distribution of baits ...
Sarker Mahfuzur R - - 2013
Abstract High hydrostatic pressure (HHP) is the most-widely adopted novel non-thermal technology for the commercial pasteurization of foods. However, HHP-induced inactivation of bacterial spores remains a challenge due to spore resistance to the treatment limits of currently available industrial HHP units (i.e. ∼650 MPa and 50 °C). Several reports have demonstrated that ...
Daigle Patrick - - 2013
Negative-pressure wound therapy (NPWT) has significantly improved healing rates and patient comfort since its inception. However, a considerable number of questions have been raised regarding its mechanisms of action. Many health care workers and researchers have attempted to clarify the role of NPWT in wound healing. The purpose of this ...
Fujiwara Toshihiro - - 2013
Abstract Negative pressure wound therapy is helpful and effective in the treatment of intractable skin ulcers and defects, not only acute wounds. However, application of negative pressure wound therapy for an infected wound is still controversial. The authors developed an in-vitro model of negative pressure wound therapy and investigated the ...
Yüzbaşıoğlu Emir - - 2013
Keloids are considered aberrations of the wound healing process, and various treatment regimens are described depending on the morphology and size of the lesion. Compression therapy using custom-made pressure clips or splints is widely used for the treatment of keloids. The most common complication of this therapy is ulceration due ...
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