Search Results
Results 201 - 250 of 1646
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Rhee Yun-Seok - - 2008
The aim of this study was to investigate the effect of the functional groups in acrylic adhesive on tulobuterol uptake, release rate and permeation rate across rat dorsal skin. In addition, the relationship between these parameters was identified in order to formulate the monolithic matrix patch system. Seven acrylate pressure ...
Karagulle Erdal - - 2008
This study aimed to examine the effects of differing intra-abdominal pressures on pulmonary function test results in laparoscopic cholecystectomy. Forty-five patients were operated on under 3 different intra-abdominal pressures: group A (8 mm Hg), group B (12 mm Hg), and group C (15 mm Hg). On the first day before ...
Arkadopoulos Nikolaos - - 2008
Oxidative mechanisms have been implicated in the pathogenesis of brain edema in acute liver failure (ALF). The aim of this study was to test the hypothesis that inhibition of iron-catalyzed oxidative reactions through iron chelation using deferoxamine could attenuate brain edema in a swine model of ischemic ALF. Following ALF ...
Kumagai Motoi - - 2008
BACKGROUND: Intracisternal dexmedetomidine (Dex) attenuates cardiac dysfunction in rats with intracranial hypertension (ICH). However, the effects of IV Dex on cardiac function and lung permeability during ICH have not been evaluated. We tested the hypothesis that IV Dex attenuates hemodynamic changes and decreases lung permeability induced by ICH in rats. ...
Loeffelbein Florian - - 2008
OBJECTIVE: To evaluate the influence of high colloid oncotic pressure (COP) priming of cardiopulmonary bypass (CPB) on fluid balances, haemofiltration, capillary leakage and renal function in neonates and infants. METHODS: Twenty neonates or infants underwent heart surgery using CPB and were randomised in two groups. For group 1 (FFP-group) a ...
Uyar Ahmet Senol - - 2008
We tested dexmedetomidine, an alpha2 agonist, for its ability to decrease heart rate, arterial blood pressure, and neuroendocrinal responses to skull-pin head-holder application during craniotomy. In a randomized, double-blinded, placebo-controlled study, 40 patients undergoing craniotomy with attachment of a pin head-holder were randomly assigned to one of 2 equal groups. ...
El-Shafey E M - - 2008
BACKGROUND: The etiology of hemodialysis (HD)-induced hypotension and hypertension remains speculative. There is mounting evidence that endothelin-1 (ET-1) may play a vital role in these hemodynamic changes. We examined the possible role of intradialytic changes of ET-1 in the pathogenesis of hypotension and rebound hypertension during HD. METHODS: The present ...
Su Antonio - - 2008
Introduction: Radial arterial pressure during and after cardiopulmonary bypass can underestimate the central arterial pressure (1). This problem can lead to erroneously exaggerated use of vasopressors. This study examines potential risk factors associated with an increased in femoral-to-radial arterial pressure during cardiopulmonary bypass. METHODS: After ethics board approval, this retrospective ...
Kamisaka Keiko - - 2008
BACKGROUND: Large-shunt ventricular septal defect (VSD) infants manifest varied serious symptoms resulting from peripheral arterial constriction to compensate for increased pulmonary blood flow (Qp) and concomitantly decreased systemic blood flow (Qs). The aim of the present paper was therefore to estimate the whole arterial space proximal to arterioles as the ...
Song Hong-Ping - - 2008
OBJECTIVE: The purpose of this study was to investigate the feasibility of percutaneous microwave coagulation therapy (PMCT) guided by contrast-enhanced ultrasonography (CEUS) for controlling active bleeding in rabbit livers. METHODS: Twenty actively bleeding rabbit liver models, produced with an 18-gauge semiautomatic biopsy needle and confirmed with CEUS, were randomly divided ...
Enouri Saad S - - 2008
OBJECTIVE: To evaluate the effects of administration of a peripheral alpha(2)-adrenergic receptor antagonist (L-659,066), with and without concurrent administration of glycopyrrolate, on cardiopulmonary effects of medetomidine administration in dogs. ANIMALS: 6 healthy adult dogs. PROCEDURES: Dogs received saline (0.9% NaCl) solution (saline group), L-659,066 (group L), or L-659,066 with glycopyrrolate ...
Leppikangas H - - 2008
BACKGROUND: Levosimendan has a dual mechanism of action: it improves myocardial contractility and causes vasodilatation without increasing myocardial oxygen demand. In a laboratory setting, it selectively increases gastric mucosal oxygenation in particular and splanchnic perfusion in general. The aim of our study was to describe the effects of levosimendan on ...
Korkmaz Hasan - - 2008
The objective of the present study was to compare the early effects of treatment with nebivolol and quinapril on the endothelial function in hypertensive patients. A total of 54 hypertensive patients was enrolled in the present study. One of the groups (n = 27) received quinapril 20 mg/day, and the ...
Tribuddharat Sirirat - - 2008
OBJECTIVE: Compare the increase in heart rate in adults after 0.9 vs. 1.2 mg of atropine plus neostigmine 2.5 mg as the non-depolarizing muscle relaxant reversal agent. MATERIAL AND METHOD: A randomized, double blind, controlled trial on 46 adults ASA I-II, undergoing elective gynecological or general surgery with balanced general ...
Elamin Elamin M - - 2008
BACKGROUND: Tracheal dyskinesia (TD) was recently recognized as a possible mechanism for acute pulmonary edema (Elamin and Firdose, J Bronchol 2004;11:118-21; Khan and Elamin Eur Respir J 2005;26:319). This study was designed to evaluate possible impact of TD on cardiac hemodynamics. METHODS: Patients were prospectively assigned to either study "A" ...
Sander M - - 2008
In cardiac surgery, perioperative haemodynamic management is often guided by cardiac output (CO) measurements. The Vigileo monitor offers uncalibrated CO measurement by arterial waveform analysis (CO(wave)). This validation study compared CO measurements derived from radial artery waveform analysis with those derived from the ascending aorta. CO measurements from the radial ...
Carmona Murilo - - 2008
BACKGROUND AND PURPOSE: Carbon dioxide pneumoperitoneum is associated with significant hypercarbia and acidosis. The aim of this study is to evaluate the effects of carbon dioxide and helium pneumoperitoneum on renal function. MATERIALS AND METHODS: Thirty adult dogs were put randomly into one of three groups (n=10 animals each): group ...
Aysan Erhan - - 2008
BACKGROUND: The morbidity and mortality rates of anastomosis leakage of the gastrointestinal system, are high. In this study we covered the colonic anastomosis with polypropylene mesh on the safety of the anastomosis was investigated. METHODS: Twenty female albino rabbits were divided into two groups. First of all, a segmental colon ...
Bingener Juliane - - 2008
BACKGROUND: Anecdotal reports of natural orifice translumenal endoscopic surgery (NOTES) procedures in patients are emerging. Whether the new procedure is truly less invasive is not known. We compared perioperative cardiopulmonary parameters during NOTES with standard laparoscopy. METHODS: Twelve swine were randomized to transgastric peritoneoscopy with air or diagnostic laparoscopy with ...
Van Mukaddes - - 2008
INTRODUCTION: The harmful effects of ischaemia-reperfusion on skeletal muscle during extremity surgery can be diminished by using medications or ischaemic preconditioning METHODS: Twenty patients undergoing lower-limb surgery with use of a tourniquet for at least 1 hour were included in the study and randomised into two groups: a control group ...
Kim H J - - 2008
BACKGROUND AND OBJECTIVES: Plateletpheresis is the most frequent type of apheresis, with demand for these products continuously increasing. Hypothermia is a common side-effect of apheresis, which may have an effect on the donor's body functions. The aim of this study was to examine the effects of warming methods on plateletpheresis ...
Caille Vincent - - 2008
OBJECTIVES: To determine the effects of passive leg raising (PLR) on hemodynamics and on cardiac function according to the preload dependency defined by the superior vena cava collapsibility index (DeltaSVC). RESULTS: Forty patients with shock, sedated and mechanically ventilated, were included. Transesophageal echocardiography was performed. At baseline (T1), two groups ...
Simpson Ian D - - 2008
Pressure immobilisation (PIM) has been recommended for field management of bites by some venomous snakes. A narrow range of pressures under the encompassing wrap is necessary for PIM to limit venom spread. This study sought to evaluate the effect of focused training on volunteers' ability to apply PIM and to ...
Yeginsu A - - 2008
OBJECTIVE: The purpose of this study was to investigate the effects of different bronchial suture techniques, with and without tissue reinforcement, on the resistance to pressure of the bronchial stump. MATERIALS AND METHODS: Fifty-four tracheo-bronchial trees obtained from the local slaughterhouse were prepared for manual closure. After right pneumonectomy, specimens ...
Urdaneta F - - 2008
Procedures using cardiopulmonary bypass (CPB) and aortic cross-clamping are associated with a variable degree of ischemia/reperfusion of the lungs, leading to acute pulmonary hypertension (PHT). The purpose of this study was to compare the effects of the sildenafil analog (UK343-664), a phosphodiesterase type V(PDEV) inhibitor, with milrinone, a PDE type ...
Zheng Chuan-dong - - 2008
OBJECTIVE: To investigate the protective effect of Shenfu Injection (SFI) against myocardium ischemia/reperfusion injury (IRI) in mitral valve replacement (MVR) with cardiopulmonary bypass (CPB). METHODS: Forty patients undergoing selective MVR were randomly assigned to the control group and trial Groups I, II, III, and IV according to the different administrations ...
Yilmaz Ismail - - 2008
To study the effects of various densities of middle ear fluids on acoustic immittance and elucidate the characteristics of this study that might be beneficial for clinical use in otitis media with effusion. Experimental, in vivo model. The study was performed on 12 ears of six white Vienna rabbits. Rabbits ...
Kvalheim Venny L - - 2008
OBJECTIVE: Cardiopulmonary bypass (CPB) is associated with fluid overload. We examined how a continuous infusion of hypertonic saline/dextran (HSD) influenced fluid shifts during CPB. MATERIALS AND METHODS: Fourteen animals were randomized to a control-group (CT-group) or a hypertonic saline/dextran-group (HSD-group). Ringer's solution was used as CPB-prime and as maintenance fluid ...
Wang Zhi - - 2008
In order to explore the changes and the roles of TXA2 and PGI2 during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage, 31 cases subject to craniotomy were divided into three groups: group A, 9 patients with postoperative hypertensive crisis; group B, 13 patients without postoperative hypertensive crisis; and ...
Pitombo Marcos Bettini - - 2008
PURPOSE: To asses the dissemination of bacteria labeled with technetium-99m (99mTc) from peritoneal cavity after different surgical procedures. METHODS: Bacteria of the Escherichia coli species labeled with 99mTc were used in a concentration of 10(8) units of colony-makers for ml (UFC/ml) and 1 ml was inoculated through intra-peritoneal via. Forty-eight ...
Sato Koichi - - 2008
Studies have demonstrated that cardiopulmonary bypass (CPB) adversely affects pulmonary circulation, which is involved in metabolism in the lung, and that pulmonary circulation after CPB can restore the prostaglandin E2 (PGE2) level mainly standing for levels of key vasostimulators augmented during CPB, which may influence systemic tissue perfusion and body ...
Lorenzoni A G - - 2008
The pathogenesis of pulmonary hypertension syndrome (PHS, ascites) includes the development of systemic arterial hypoxemia (reduction in the saturation of hemoglobin with O(2), HbO(2)), which can be mimicked in clinically healthy broilers by i.v. injections of microparticles (MP). In experiment 1, arterial blood samples were collected from clinically healthy broilers ...
Dias Taísa Silva - - 2008
OBJECTIVE: To determine the blood recirculation ratio in the vascular access of patients on hemodialysis, and to calculate the Kt/Vs obtained with the different techniques of arteriovenous fistula punctures. MATERIALS AND METHODS: A total of 174 patients were divided according to the technique used for arteriovenous fistula puncture: group 1, ...
Kapoor Poonam Malhotra - - 2008
Early goal-directed therapy is a term used to describe the guidance of intravenous fluid and vasopressor/inotropic therapy by using cardiac output or similar parameters in the immediate post-cardiopulmonary bypass in cardiac surgery patients. Early recognition and therapy during this period may result in better outcome. In keeping with this aim ...
Meirelles Roberto Ferreira RF - - 2008
PURPOSE: Study hemodynamic pattern and lipoperoxidation during methylene blue (MB) treatment on taurocholate - enterokinase induced acute pancreatitis (AP). METHODS: Thirty pigs were equally divided in control group; MB group; AP group; MB previous AP group; and MB after 90 min of induced AP group. MB was given iv in ...
Jiang Jia - - 2008
OBJECTIVE: To study the proliferation of artery after hydraulic dilation under different pressures. MATERIAL AND METHODS: Right carotid arteries of New Zealand white rabbits (group A, B, C, D) were dilated by hydraulic dilation under different pressures (0, 40, 80, 120 Kpa). The arterial caliber, thickness of tunica intima (TI) ...
Soma Tomoyuki - - 2008
OBJECTIVE: We hypothesized that non-invasive positive pressure ventilation (NPPV) would improve an acute asthma attack in mild to moderate cases without bronchodilator therapy. METHODOLOGY: A total of 44 eligible patients with acute asthma of mild to moderate severity who had acute attacks were randomly allocated to a NPPV (n=30) or ...
Miyamoto Takashi - - 2008
We examined the hypothesis that higher cerebral oxygen saturation (rSO2) during RCP is correlated with urinary output. Between December 2002 and August 2006, 12 patients aged 3 to 61 days and weighing 2.6 to 3.4 kg underwent aortic arch repair with RCP. Urinary output and rSO2 were analyzed retrospectively. Data ...
Fassoulaki Argyro - - 2008
Gabapentin is an adjuvant analgesic and may enhance the spread of subarachnoid block. We investigated the effects of pretreatment with gabapentin on subarachnoid block characteristics and hemodynamics. Seventy patients undergoing transurethral procedures under subarachnoid anesthesia with 2.2 mL of 0.75% ropivacaine were randomly assigned to receive preoperatively 400 mg of ...
Gehlen Heidrun - - 2008
The aim of this study was to investigate the potential haemodynamic effects of valvular insufficiency and recurrent airway obstruction (RAO) in horses with atrial fibrillation (AF). Therefore in ten healthy horses (group 1) and 40 horses with AF a clinical examination, a lung examination, echocardiography and right heart catheterization for ...
Zhu Guang-fa - - 2007
BACKGROUND: Although severe encephalopathy has been proposed as a possible contraindication to the use of noninvasive positive-pressure ventilation (NPPV), increasing clinical reports showed it was effective in patients with impaired consciousness and even coma secondary to acute respiratory failure, especially hypercapnic acute respiratory failure (HARF). To further evaluate the effectiveness ...
Aslan Adnan - - 2008
BACKGROUND: We aimed to test the efficacy and safety of closure of the appendeceal stump with only laparoscopic bipolar electrocautery in rats. METHODS: In this study, 40 female Wistar-Albino rats were used. In group I (n = 10), appendix vermiformis, approximately 1 cm in width, was completely ligated with 3/0 ...
Lee Jeong Min - - 2007
PURPOSE: To compare in vivo efficacy of multipolar radiofrequency (RF) ablation with two internally cooled electrodes to that of monopolar RF ablation with internally cooled single and cluster needles to induce coagulation in in vivo porcine kidneys. MATERIALS AND METHODS: Twenty-four coagulations were created in the kidneys of 12 pigs ...
Tong Chang-qing - - 2007
OBJECTIVE: To investigate the effect of Yiqi Huoxue Recipe (YHR) on the cardiac function and ultrastructure during the regression of myocardial hypertrophy induced by pressure overload in rats. METHODS: The model of myocardial hypertrophy was established by abdominal aortic banding. Eighty male Wistar rats were divided into six groups, the ...
Liu C-C - - 2007
A new preservation method using perfluorochemicals (PFC) with oxygen administered continuously was developed for lung preservation and compared with traditional cold preservation methods for rat lung transplantation. Male Sprague-Dawley rats underwent orthotopic left lung transplantations of grafts preserved in lactiated Ringers solution (LR), University of Wisconsin solution (UW), Celsior solution, ...
Fannelop Tord - - 2008
OBJECTIVE: Myocardial dysfunction after reperfusion can be a clinical problem in the early postoperative phase after on-pump cardiac surgery. The aim was, in an experimental setting, to investigate if administration of the beta-adrenergic receptor blocker esmolol prior to cross-clamping for 80 min with cold oxygenated blood cardioplegia would improve myocardial ...
Burdío F - - 2008
AIMS: Radiofrequency ablation (RFA) of tumors by means of internally cooled (ICE) or multitined expandable electrodes combined with infusion of saline into the tissue may improve results. Our aim was to determine the efficacy of a previously optimized hybrid ICE system (ICE combined with infusion of saline into the tissue ...
Youssef Mohamed A M - - 2008
BACKGROUND: Many studies have demonstrated the adverse consequences of pneumoperitoneum. However, few studies have examined the physiologic effects of pneumoperitoneum in adults with sickle cell disease (SCD) during laparoscopic cholecystectomy (LC). METHODS: 60 ASA 1-capital PE, Cyrillic capital PE, Cyrillic patients, with cholelithiasis, scheduled for elective LC were allocated into ...
Kasama Shu - - 2007
The activation of the renin-angiotensin-aldosterone system prevents the uptake of norepinephrine in the myocardium. However, the additive effects of combined spironolactone and candesartan on cardiac sympathetic nerve activity (CSNA) have not been determined. We investigated the effects of the angiotensin-receptor blocker candesartan alone and in combination with spironolactone on CSNA ...
Babalola O. O.
The possible association between selenium and essential hypertension was investigated in this study. Blood selenium (BSe) and plasma glutathione peroxidase (plGSH-Px) activity were measured as biochemical markers of selenium status of 103 hypertensive patients (44 males and 59 females) and 88 apparently healthy subjects (40 males and 48 females). The ...
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