Search Results
Results 451 - 500 of 1661
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Manecke Gerard R GR - - 2004
OBJECTIVES: To determine the femoral-to-radial arterial pressure gradient, as well as the factors associated with them, in patients receiving cardiopulmonary bypass (CPB) with profound hypothermia and circulatory arrest. DESIGN: Retrospective automated hemodynamic record review. SETTING: University hospital. PARTICIPANTS: Patients undergoing pulmonary thromboendarterectomy with deep hypothermic circulatory arrest. MEASUREMENTS AND MAIN ...
Dodam John R - - 2004
OBJECTIVES: To determine if chronic selegiline HCl administration affects the cardiopulmonary response to medetomidine, oxymorphone, or butorphanol in dogs. STUDY DESIGN: Prospective randomized experimental study. ANIMALS: Twenty-eight adult, random source, hound dogs weighing 21-33 kg. METHODS: Dogs were assigned to the following treatment groups: selegiline + medetomidine (MED; n = ...
Hubble Christopher L - - 2004
OBJECTIVE: To evaluate if inhaled nitric oxide (iNO) has a lung-protective effect when it is delivered during the ischemic phase of neonatal cardiopulmonary bypass (CPB). DESIGN: Prospective, randomized, controlled study. SETTING: Surgical research laboratory in a university hospital. SUBJECTS: Thirty-five neonatal swine. INTERVENTIONS: One-week-old swine (2.1-3.4 kg) were exposed to ...
Wei Bo - - 2004
BACKGROUND: The aim of this study was to evaluate the protective effect of pulmonary perfusion with hypothermic protective solution on lung function after cardiopulmonary bypass in corrections of Tetralogy of Fallot. METHODS: Sixty-four consecutive children with Tetralogy of Fallot were randomly divided into a control group (n = 30) and ...
Rosenthal David N - - 2004
BACKGROUND: There has been a continued search for alternative diagnostic techniques that do not necessitate endomyocardial biopsy for diagnosing rejection in cardiac transplant recipients. The purpose of this study is to evaluate the role of echocardiography and hemodynamic catheterization data compared with endomyocardial biopsy results, in rejection surveillance for the ...
Ngan Kee Warwick D - - 2004
In a randomized, double-blinded, controlled trial, we investigated the prophylactic infusion of IV phenylephrine for the prevention of hypotension during spinal anesthesia for cesarean delivery. Immediately after intrathecal injection, phenylephrine was infused at 100 microg/min (n = 26) for 3 min. From that point until delivery, phenylephrine was infused at ...
Protogerou V - - 2004
PURPOSE: To investigate the effects of shockwave lithotripsy (SWL) on blood pressure with the use of 24-hour ambulatory blood-pressure monitoring (ABPM). PATIENTS AND METHODS: We studied three groups of patients. Group I consisted of 60 patients with kidney stones treated with SWL. Group II was formed by 30 patients with ...
Farstad M - - 2004
OBJECTIVE: Hypothermic cardiopulmonary bypass is associated with capillary fluid leakage, resulting in edema and occasionally organ dysfunction. Systemic inflammatory activation is considered responsible. In some studies methylprednisolone has reduced the weight gain during cardiopulmonary bypass. Vitamin C and alpha-trinositol have been demonstrated to reduce the microvascular fluid and protein leakage ...
Guo Hangyuan - - 2004
OBJECTIVE: To study the relationship between hypertensive left ventricular hypertrophy (LVH) in very old patients (> or = 80 years) with neuro-hormonal factors and ventricular arrhythmias. METHODS: Heart rate variation, plasma renin (Ren), angiotensin-II (AT-II), aldosterone (Ald), insulin (Ins), Holter and ambulatory blood pressure monitoring were measured in 60 cases ...
Rossi Marco - - 2004
BACKGROUND: Cardiopulmonary bypass provokes a systemic inflammatory reaction that, in 1% to 2% of all cases, leads to multiorgan disfunction. The aim of this study was to evaluate the possible role of the intestine in the pathogenesis and development of this reaction. METHODS: Eleven selected patients scheduled for elective coronary ...
Ege T - - 2004
BACKGROUND: Protamine has adverse effects on pulmonary gas exchange during the postoperative period. The objective of this study was to investigate the importance of aprotinin and pentoxifylline in preventing the leukocyte sequestration and lung injury caused by protamine administered after the termination of cardiopulmonary bypass (CPB). METHODS: Participants (n = ...
Steiner Ilka M - - 2004
OBJECTIVES: To test whether norepinephrine (NOR) affects tissue microcirculation and impairs plasma-to-tissue equilibration of antimicrobial agents. MATERIALS AND METHODS: Eight healthy male volunteers were enrolled to an analyst-blinded, randomized, two-period two-sequence crossover study. A single intravenous dose of 2 g of cefpirome was administered simultaneously with starting a continuous infusion ...
Dubois J - - 2004
OBJECTIVE: A newly developed neonatal and infant oxygenator with a nonheparin biocompatible polymer coating, low priming volume (43 mL), high oxygen transfer, wide operating range (<1.5 L/min) and low pressure drop represents a promising solution for cardiac surgery in neonates and infants. We compared the new CAPIOX Baby RX, Terumo ...
Kalinowski Marc - - 2004
BACKGROUND: Efficient local gene or drug therapy requires optimized application modalities to avoid vessel damage, which might lead to increased neointimal hyperplasia. Aim of the study was to evaluate different application parameters for local delivery using the channeled balloon catheter in order to minimize vessel trauma induced by local application. ...
Fujii Yoshitaka - - 2004
The present study was undertaken to evaluate the effects of dopamine and dobutamine on diaphragmatic contractility in dogs with induced hypercapnia. Animals were divided into three groups of ten each. In each group, hypercapnia (80-90 mmHg) was produced by adding 10% CO2 to the inspired gas. When hypercapnia was established, ...
Pereira Leila M M - - 2004
Twenty mature male Wistar rats were maintained alive for 40 days, separated in four groups of five rats each: control, L-NAME (LN), L-NAME + Enalapril (LN + E), L-NAME + Verapamil (LN + V). Blood pressure (BP), left ventricular (LV) mass index, and aortic wall parameters were analyzed: aortic wall ...
Fukumura Fumio - - 2004
In neonate open-heart surgery, cardiopulmonary bypass (CPB) with extreme hemodilution induces an increased capillary permeability and accumulation of extravascular fluid, resulting in organ dysfunction. We evaluated the effects of a reduced priming volume for CPB and dilutional ultrafiltration (DUF) during neonatal open-heart surgery. Nineteen consecutive neonates with complete transposition of ...
Dolezel J - - 2004
The mean correlation curves of the intraabdominal pressure over time were evaluated by regression analysis (value 0.05) in both groups. The curves had a rising character in both groups, but in the control group the curve rose more steeply and reached a higher level than the curve of studied group. ...
Sheppard S V - - 2004
Fifty patients undergoing elective coronary revascularisation were prospectively randomised to receive either a leucocyte-depleting or a control filter inserted into the arterial line of the cardiopulmonary bypass (CPB) circuit. The concentration of exhaled nitric oxide (NO) was measured 15 min before and 30 min after CPB using a real-time chemiluminescence ...
Herring I P - - 2004
OBJECTIVE: To evaluate the effect of topical ophthalmic 10% phenylephrine on systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), pulse rate (PR) and electrocardiogram (ECG) in dogs. ANIMALS STUDIED: Nine clinically normal dogs. PROCEDURE: Arterial catheters were placed in the dorsal pedal artery of awake dogs ...
Yamada Shinichi - - 2004
We examined whether vascular endothelial function is impaired with deep hypothermia during cardiopulmonary bypass. Such impairment may cause the prolonged hypoperfusion of tissues or organs. Thirty adult patients were classified into three groups according to the degree of hypothermia during cardiopulmonary bypass; deep (DH: 18-20 degrees C, n = 10), ...
Stayer Stephen A - - 2004
Children with excessive pulmonary blood flow (PBF) from congenital heart disease have abnormal respiratory mechanics. Exposure to hypothermic cardiopulmonary bypass (CPB) adversely affects lung function. We designed this study of 106 patients to determine the changes in respiratory mechanics in infants younger than 1 yr undergoing heart surgery. Dynamic respiratory ...
Yilik Levent - - 2004
Some damage to the capillaries and increase in myocardial edema have been shown when retrograde cardioplegia perfusion pressure exceeds 40-50 mmHg, or possibly when it falls within this pressure interval. To avoid these complications, we designed a very simple delivery method for retrograde cardioplegia: passive continuous infusion by gravitational force ...
Xia Fang - - 2003
OBJECTIVE: To study the effect of methylprednisolone (MP) on reperfusion injury in severe uncontrolled hemorrhagic shock and explore the possible mechanism involved. METHODS: Twelve dogs were randomly divided into two groups, control group (Group I, n=6) and MP group (Group II, n=6). The animals were bled continuously from a femoral ...
Aybek T - - 2003
OBJECTIVE: Postoperative cardiac depression is attributed to ischemia and the effects of cardiopulmonary bypass (CPB). To evaluate the effect of CPB alone on postoperative left ventricular (LV) dysfunction, we used a conductance catheter to determine the LV performance by pressure-volume relation before and after CPB. METHODS: Twenty-two 3-week-old piglets underwent ...
Nakamura Yukio - - 2003
We examined the relation between hemodynamic changes after endoscopic transthoracic sympathicotomy (ETS) and the number of sympathetic segment operated. Cardiac functional indices using echocardiography and plasma noradrenaline concentration (NOR) were measured before and after ETS in 25 patients with palmar hyperhidrosis. Patients were divided into 2 groups. Group Th2-3 consisted ...
Cihan Alper - - 2003
BACKGROUND/AIMS: This study was designed to determine the effects of different surgeons on the experimental anastomosis studied in rats. METHODOLOGY: Sixteen Wistar-albino rats were equally separated into two groups. The rats operated on by the first surgeon were coded Group 1 and operated on by the other surgeon were coded ...
Watanabe Kenichi - - 2003
We investigated the contribution of the sympathetic nervous system (SNS) in maintaining blood pressure during administration of carvedilol in rats with dilated cardiomyopathy, and examined whether SNS hyperactivity induced by high-dose carvedilol is related to severity of heart failure. The hypotensive effect of carvedilol in rats with heart failure (Group ...
Radovancevic Branislav - - 2003
Outcomes of mechanical circulatory assistance during hemorrhagic shock were evaluated in a swine model. Pigs were bled to a mean arterial pressure of 35 mm Hg (group I, n = 3) or 40 mm Hg (group II, n = 5; group III, n = 5), maintained there for 30 minutes, ...
Inoue Masaiwa - - 2003
To determine if the type of work performed should be considered in research on shift work and cardiovascular disease, we compared the heart rates, total number of steps walked, and blood pressures of 12 shift workers on the same rotating 3-shift schedule in a pulp and paper mill. Six workers ...
Iwata Osuke - - 2003
BACKGROUND: Selective head cooling in the newborn infant has been proposed as a neuroprotective treatment with a lower level of systemic adverse effect than that of systemic hypothermia. However, the efficacy is not confirmed as well as that of systemic hypothermia. In order to analyze the safety and efficacy of ...
Soller Babs R - - 2003
OBJECTIVE: To determine whether near infrared spectroscopic measurement of tissue pH and Po2 has sufficient accuracy to assess variation in tissue perfusion resulting from changes in blood pressure and metabolic demand during cardiopulmonary bypass. DESIGN: Prospective clinical study. SETTING: Academic medical center. SUBJECTS: Eighteen elective cardiac surgical patients. INTERVENTION: Cardiac ...
Abdel-Rahman Ulf - - 2003
BACKGROUND: Most cardiac operations with cardiopulmonary bypass (CPB) are conducted with high oxygen partial pressure. The hyperoxic reoxygenation of the ischemic heart induced by aortic declamping may be an important component of cardiac reperfusion injury. The present clinical study assessed the preventive effect of graded reoxygenation on lipid peroxidation. Malondialdehyde ...
Yoshida Naohiro - - 2003
It is unknown whether the non-transplanted, denervated human heart is supersensitive to beta-adrenergic agonist in terms of inotropism and chronotropism. In the present study, 36 patients with normal left ventricular (LV) wall motion were divided into 3 groups according to the cardiac metaiodobenzylguanidine (MIBG) scintigrams: group I with normal MIBG ...
Grace F - - 2003
The literature regarding the blood pressure response to AAS use is equivocal. In addition, there is currently little data available on the Rate Pressure Product (RPP) response to anabolic androgenic steroids (AAS) use. The experimental aim of this study was to investigate the effects of AAS administration in combination with ...
Komori Makiko - - 2003
Using intravital microscopy of the rabbit ear for quantitative studies of microvascular dynamics, we examined the impact of urinary trypsin inhibitor (UTI), a proteolytic enzyme inhibitor, on microvascular changes during immune complex-mediated anaphylaxis. A total of 50 rabbits, previously sensitized with horse serum, were anesthetized and mechanically ventilated with pentobarbital ...
Perrakis E - - 2003
Laparoscopy using carbon dioxide insufflation induces adverse effects in both the cardiovascular and the respiratory function. The use of low pressure pneumoperitoneum has been shown to reduce adverse hemodynamic effects. However, its effect on tissue trauma and postoperative pain and recovery remains controversial. The aim of this study was to ...
Chang Shi-Min - - 2003
The mechanism of venous drainage in reverse-flow island flaps was investigated using the saphenous fasciocutaneous flap in New Zealand White rabbits. Ten animals were allocated into two groups of 10 flaps. In group I (left limb), the distal vascular pedicle (one saphenous artery and two venae comitantes) was not disturbed, ...
Kadoi Yuji - - 2003
STUDY OBJECTIVE: To examine whether increasing mean arterial pressure (MAP) with the administration of phenylephrine would improve internal jugular venous oxygen saturation (SjvO2) during normothermic cardiopulmonary bypass (CPB) in patients with preexisting stroke. DESIGN: Prospective, controlled study. SETTING: Cardiovascular center and university hospital. PATIENTS: 17 patients with preexisting stroke who ...
Shum-Tim Dominique - - 2003
OBJECTIVES: The contact of cardiopulmonary bypass surface and patient's blood activates systemic inflammatory response which aggravates ischemia-reperfusion injury. This study evaluates the effects of cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) on cerebral protection using different steroid administration protocols. METHODS: Eighteen (n=6/group) 4 week-old piglets were divided in ...
Redlich Meir - - 2003
This study evaluated the static friction force created between archwires and "reduced-friction" brackets during sliding mechanics. Five different brands of "reduced-friction" brackets were used: group A: NuEdge (TP Orthodontics, LaPorte, Ind); group B: Discovery (Dentaurum, Ispringen, Germany); group C: Synergy (Rocky Mountain Orthodontics, Denver, Colo); group D: Friction Free (American ...
Karahasanoglu T - - 2003
BACKGROUND: The standard treatment of iatrogenic perforation has been an urgent operation. Recently, endoscopic clip application was recommended particularly for iatrogenic perforations. This study was designed to investigate the usage of surgical clips for gastric perforations. METHOD: Forty male rats were allocated to four groups. Following a midline laparotomy, a ...
Giomarelli Pierpaolo - - 2003
BACKGROUND: Proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-6, and IL-8 play a key role in the inflammatory cascade after cardiopulmonary bypass (CPB) and may induce cardiac and lung dysfunction. Antiinflammatory cytokines such as IL-10 may also significantly limit these complications. Corticosteroid administration before CPB increases blood IL-10 ...
von Segesser Ludwig K - - 2003
Cardiopulmonary bypass (CPB) remains the key technology for more complex cardiac operations. The perfusion equipment used nowadays has seen tremendous progress since its introduction into clinical practice 50 years ago. However, overall, CPB is still far from perfect. Major haemodilution is not only a problem for red cell-dependent gas transport, ...
Ziser Avishai - - 2003
OBJECTIVE: To assess the effect of diisopropyl phenol (propofol), with and without Intralipid, on the cardiopulmonary system and on thromboxane production in endotoxic pigs. DESIGN: Prospective, randomized animal study. SETTING: Animal research laboratory at a major teaching hospital. SUBJECTS: Twenty-four pigs, divided into three groups (n = 8). INTERVENTIONS: Pulmonary ...
Koike Norimasa - - 2003
BACKGROUND: We investigated the effects of briefly perfusing hearts from non-heart-beating donors (NHBDs) with a Celsior solution before cardiac transplantation. METHODS: Donor hearts were left in situ for 20 minutes after cardiac arrest was induced by rapid exsanguination. Twelve donor-recipient pairs of mongrel dogs were divided into 2 groups, the ...
Sun Qinghua - - 2003
After induction of cecal perforation, 20 anesthetized sheep were randomized to be treated, when arterial blood pressure fell below 75 mm Hg, with vasopressin (fixed dose of 0.02 U/minute), norepinephrine (0.5-5 microg/kg/minute titrated to maintain mean arterial pressure between 75 and 85 mm Hg), vasopressin + norepinephrine (vasopressin at fixed ...
Grooters Ronald K - - 2003
BACKGROUND: Dislodgement of aortic arch atheroma caused by a perfusion "jet" from the aortic cannula may be a major cause of atheroemboli during coronary artery surgery when using cardiopulmonary bypass (CPB). Two very different cannulas, the Soft-Flow aortic cannula and the Dispersion cannula, which have been designed to reduce exit ...
Wu Ming - - 2003
OBJECTIVE: To investigate the fluctuations in arterial leukocyte phospholipase D (PLD) activity during the perioperative period of open heart surgery under cardiopulmonary bypass (CPB), and the relationship between PLD activity and systemic inflammatory response induced by CPB. METHODS: Arterial blood was obtained from 26 patients undergoing open heart surgery at ...
Sasso F - - 2003
PURPOSE: We evaluated corpora cavernosa metabolism in flaccidity and in erection, analyzing some blood gas analytical parameters and comparing them by histomorphometric examination to find a direct relation between biochemical-metabolic parameters and histological data. MATERIALS AND METHODS: We selected 33 patients with erectile dysfunction and divided them into 2 groups, ...
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