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Corzo-Martínez M M Department of Food Science and Technology, The University of Tennessee, 2605 River Dr., Knoxville, Tennessee, 37996-4539, - - 2014
The aim of this work was to develop a milk-based powder formulation appropriate for pediatric delivery of ritonavir (RIT). Ultra-high pressure homogenization (UHPH) at 0.1, 300 and 500 MPa was used to process a dispersion of pasteurized skim milk (SM) and ritonavir. Loading efficiency was determined by RP-HPLC-UV; characterization of RIT:SM ...
Diallo S O SO Quantum Condensed Matter Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, - - 2014
We present a pressure-dependence study of the dynamics of lysozyme protein powder immersed in deuterated α,α-trehalose environment via quasielastic neutron scattering (QENS). The goal is to assess the baroprotective benefits of trehalose on biomolecules by comparing the findings with those of a trehalose-free reference study. While the mean-square displacement of ...
Nucci Nathaniel V NV Department of Biochemistry and Biophysics and Johnson Research Foundation, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA - - 2014
It is well known that high hydrostatic pressures can induce the unfolding of proteins. The physical underpinnings of this phenomenon have been investigated extensively but remain controversial. Changes in solvation energetics have been commonly proposed as a driving force for pressure-induced unfolding. Recently, the elimination of void volumes in the ...
Suladze Saba S TU Dortmund University, Department of Chemistry and Chemical Biology, Physical Chemistry - Biophysical Chemistry, Otto-Hahn Str. 6, D-44227 Dortmund, - - 2014
Pressure perturbation calorimetry (PPC) is a efficient technique to study the volumetric properties of biomolecules in solution. In PPC, the coefficient of thermal expansion of the partial volume of the biomolecule is deduced from the heat consumed or produced after small isothermal pressure-jumps. The expansion coefficient strongly depends on the ...
Koller Ulrich U Department of Orthopaedics, Vienna General Hospital, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, 1090, - - 2014
Due to the pathoanatomical changes in hallux valgus feet, the plantar flexion moment of the first metatarsophalangeal joint is reduced. Therefore, load bearing of the hallux is decreased during push-off. We assessed loading parameters in hallux valgus feet. Based on dorsal-plantar weight bearing radiographs of 61 feet, the intermetatarsal-, hallux ...
Wiggermann Neal N Department of Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, USA. Electronic address: - - 2014
Mechanisms that cause foot discomfort during prolonged standing are poorly understood. There is currently no method for evaluating discomfort associated with low levels of static pressure that are typical during standing. Pain thresholds were measured for 20 healthy participants by applying five levels of static pressure at different plantar foot ...
Spirka Thomas A TA Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, - - 2014
Therapeutic footwear is frequently prescribed in cases of rheumatoid arthritis and diabetes to relieve or redistribute high plantar pressures in the region of the metatarsal heads. Few guidelines exist as to how these interventions should be designed and what effect such interventions actually have on the plantar pressure distribution. Finite ...
Sacco Isabel C N IC University of São Paulo, School of Medicine, Physical Therapy, Speech and Occupational Therapy Department, São Paulo, SP, Brazil. Electronic address: - - 2014
Inconsistent findings with regard to plantar pressure while walking in the diabetic population may be due to the heterogeneity of the studied groups resulting from the classification/grouping criteria adopted. The clinical diagnosis and classification of diabetes have inherent uncertainties that compromise the definition of its onset and the differentiation of ...
Jeevanantham Vinodh V Department of Cardiology, University of Kansas Medical Center, Kansas City, - - 2014
Ankle-brachial index (ABI) is conventionally derived as the ratio of higher of the 2 systolic ankle blood pressures to the higher brachial pressure (HABI method). Alternatively, ABI may be derived using the lower of the 2 systolic ankle pressures (LABI method). The objective of this study was to assess the ...
Pataky Todd Colin TC a Department of Bioengineering , Shinshu University , Ueda , - - 2014
Abstract Disagreements exist in the literature regarding the manner in which weight should be dynamically shared during the golf swing, both within-feet and between the back- and target-foot, to generate maximal clubhead speed. The purpose of this study was to determine whether preferential foot-loading locations underlie weight sharing by examining ...
Gyawali Prajwal P Biomedical Sciences, School of Community Health, Charles Sturt University. Electronic address: - - 2014
Microvascular dysfunction is associated with metabolic syndrome (MetS) and its components. The objective of our study was to assess macro and microvascular abnormalities in MetS and compare the strength of association of the ankle blood pressure index (ABPI), toe blood pressure index (TBPI) and hemorheological parameters with MetS. 100 participants ...
Chatzistergos Panagiotis E PE CSHER, Faculty of Health Sciences, Staffordshire University, Stoke-on-Trent, United Kingdom. Electronic address: - - 2014
The purpose of this study is to demonstrate a new MRI compatible loading device capable of reconstructing realistic loading scenarios of the human foot for research in the field of foot biomechanics. This device has two different configurations: one used to compress the forefoot and one to bend the metatarsophalangeal ...
Bowling K K Peninsula Deanery, Torbay, UK - - 2014
Thromboembolic detterrent (TED) stockings have been shown to be effective in the reduction of thromboembolic events in post operative patients. These manufactured stockings create graduated compression from ankle to calf. To assess whether the manufacturers' recommendations for application were being met in a District general hospital setting and whether this ...
King Christy M CM Attending Surgeon, Kaiser San Francisco Bay Area Foot and Ankle Residency, Kaiser Foundation Hospital, Oakland, CA. Electronic address: - - 2014
Hallux valgus with or without first ray insufficiency has been strongly implicated as a contributing factor in lesser metatarsal overload. The principle goals of a bunionectomy are to relieve the pain, correct the deformity, and restore first metatarsophalangeal joint congruity. Until now, little evidence has been available to assess the ...
Tiffreau V V Center for Neuromuscular Disorders, Department of Physical and Rehabilitation Medicine, LilleUniversity Medical Centre and University of Lille Nord de France, F--59037 Lille cedex, France - - - 2014
Introduction: In a 12--year old girl suffering from autosomal recessive axonal Charcot--Marie--Tooth neuropathy, pes cavovarus was treated with botulinum toxin injection in the tibialis posterior. Case report: The patient underwent a clinical evaluation, video analysis of spatiotemporal gait parameters and dynamic foot plantar pressure assessment before treatment and then two ...
Pirozzi Kelly K Chief Resident, Temple University Hospital Podiatric Surgical Residency Program, Temple university Hospital, Philadelphia, Pennsylvania, - - 2014
Objective: There is a growing body of evidence implicating obesity as having a negative effect on the development and treatment of diabetic foot disease. The aim of this study was to increase the body of knowledge on the effects of obesity on foot function, specifically as it relates to peak ...
Kernozek T W TW Department of Health Professions, University of Wisconsin-La Crosse, La Crosse, WI, - - 2014
Recent trends promote a "barefoot" running style to reduce injury. "Minimalist" shoes are designed to mimic the barefoot running with some foot protection. However, it is unknown how "minimalist" shoes alter plantar loading. Our purpose was to compare plantar loads between rearfoot strikers and non-rearfoot strikers after 4 weeks of ...
Chai Lichen L Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences, P.O. Box 1129, Hefei 230031, People's Republic of China. xbwu@issp.ac.cn - - 2014
The grain contact force, the key player in determining the mechanical properties of grain materials, depends on the elastic modulus and deformation (δ) of grains. However, our knowledge on their relationship in a three-dimensional granular medium is limited mainly owing to the difficulty of realizing direct experimental investigation. Using a ...
Elliott Henry L HL Henry L Elliott, Institute of Pharmaceutical and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, United - - 2014
To undertake a review of the evidence that nifedipine GITS and lercanidipine are therapeutically equivalent in the management of essential hypertension. A systematic review of the published literature was prompted by the findings of two meta-analyses which indicated that there was a lower incidence of peripheral (ankle) oedema with lercanidipine. ...
Becker James J Motion Analysis Laboratory, Department of Human Physiology, University of Oregon, Eugene, OR 97403-1240, - - 2014
This study examined differences in center of pressure (COP) trajectories between shod and barefoot running. Ten habitually shod runners ran continuous laps under both shod and barefoot conditions. The COP trajectory was calculated in the global coordinate system but then transformed to the anatomic coordinate system of the foot. The ...
Bergstra S A SA Centre for Human Movement Sciences, University Medical Center Groningen, University of Groningen, Groningen, The - - 2014
Minimalist running shoes have been proposed as an alternative to barefoot running. However, several studies have reported cases of forefoot stress fractures after switching from standard to minimalist shoes. Therefore, the aim of the current study was to investigate the differences in plantar pressure in the forefoot region between running ...
Portela Fellipe M FM a Laboratory of Computational Simulation and Modeling in Rehabilitation, Centro Universitário Augusto Motta , Rio de Janeiro , - - 2014
ABSTRACT The spatial distribution of center-of-pressure speed during postural tasks and its changes due to somatosensory constraint (temporary ischemic hypoxia on ankle/feet) were investigated in young, healthy subjects (n = 13). A single high-speed region in the central region of the statokinesigram was observed during postural tasks with full sensory ...
Amemiya Ayumi A The University of Tokyo, Department of Wound Care Management, Graduate School of Medicine, - - 2014
High plantar pressure is a major risk factor for diabetic foot ulcers. The relationship between plantar pressure and foot mobility has been investigated in some studies. However, when the foot is in motion, foot mobility is only a small feature of the gait. Therefore, we investigated relationship between high plantar ...
Hurn Sheree E SE Queensland University of Technology, School of Clinical Sciences, Kelvin Grove, QLD, 4059, Australia; Queensland University of Technology, Institute of Health and Biomedical Innovation, , Kelvin Grove, QLD, 4059, - - 2014
Objective: Hallux valgus has been linked to functional disability and increased falls risk, but mechanisms underpinning functional disability are unclear. This study investigated functional performance, muscle strength and plantar pressures in adults with mild, moderate, and severe HV compared to controls, while considering the influence of foot pain. Methods: Sixty ...
Riddiford-Harland Diane L DL 1Biomechanics Research Laboratory, Faculty of Science, Medicine & Health, University of Wollongong, NSW, Australia; 2Interdisciplinary Educational Research Institute, Faculty of Social Sciences, University of Wollongong Northfields Ave, Wollongong, NSW, Australia; 3Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, NSW, Australia; 4University of Sydney Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, NSW, - - 2014
To establish whether the peak plantar pressures generated by overweight and obese school-aged children during walking were associated with their objectively measured physical activity. Physical activity levels of a subset of 73 overweight/obese children from an RCT (mean ± SD age 8.3 ± 1.1 y, 47 girls, BMI z-score 2.7 ...
Godi Marco - - 2014
Previous studies have assessed reliability of insole technology for evaluating foot pressure distribution during linear walking. Since in natural motion straight walking is intermingled with turns, we determined the test-retest reliability of insole assessment for curved as well as linear trajectories, and estimated the minimum number of steps required to ...
Yiou Eric E Laboratory CIAMS (Complexité, Innovation, Activités Motrices et Sportives), Team MHAPS (Mouvement Humain, Adaptation et Performance Sportive), EA 4532, UFR STAPS, University of Paris-Sud, 91440, Orsay Cedex, France, - - 2014
We investigated whether ankle loading modifies the relationship between temporal pressure and motor coordination during a whole-body paired task. Eight young healthy adults standing in an erect posture performed multiple series of simultaneous rapid leg flexions paired with ipsilateral index finger extensions. They repeated the task ten times in three ...
Branthwaite Helen H Centre for Sport, Health and Exercise Research, Faculty of Health Sciences, Staffordshire University, Leek Road, Stoke on Trent ST4 2DF, United Kingdom. Electronic address: - - 2014
Uncomfortable shoes have been attributed to poor fit and the cause of foot pathologies. Assessing and evaluating comfort and fit have proven challenging due to the subjective nature. The aim of this paper is to investigate the relationship between footwear characteristics and perceived comfort. Twenty-seven females assessed three different styles ...
Metzler Kimberly M KM From the Department of Biomedical Engineering (Metzler, Mahmoud, Liu, Roberts) and the Department of Ophthalmology (Liu, Roberts), The Ohio State University, Columbus, Ohio, - - 2014
To evaluate the influence of ocular shell biomechanical characteristics on corneal deformation response to an air puff. The Ohio State University, Columbus, Ohio, USA. Experimental study. Twenty-four eyes of 12 human donors were obtained in matched pairs. One eye was secured in a purpose-designed whole globe mount (whole-globe group). The ...
Freitas Dayana D University of São Paulo at Ribeirão Preto College of Nursing, São Paulo, Brazil. Electronic address: - - 2014
The aim in this study was to identify the cardiovascular risk in patients suffering from white coat hypertension (WCH) by determining the ankle brachial index (ABI) with an automatic oscillometric sphygmomanometer. The study was undertaken in a Brazilian city between August 2010 and June 2011. The study variables were age, ...
Abe Yota Y Graduate School of Health Sciences, Gunma University, Japan ; Department of Rehabilitation, Gunma University Hospital, - - 2014
[Purpose] This study aimed to investigate the postural control characteristics of individuals with and without a history of ankle sprain during single-leg standing by examining the relationship between various parameters of center of pressure (COP) and head and foot acceleration. [Subjects] Twenty subjects with and 23 subjects without a history ...
de Castro Marcelo P - - 2014
Because walking is highly recommended for prevention and treatment of obesity and some of its biomechanical aspects are not clearly understood for overweight people, we compared the absolute and normalized ground reaction forces (GRF), plantar pressures, and temporal parameters of normal-weight and overweight participants during overground walking. A force plate ...
Hunt Kenneth J - - 2014
Fractures of the fifth metatarsal base are a relatively common injury. Whether treated surgically or non-surgically, injury rehabilitation typically involves immobilization in a rigid sandal or short CAM walker boot. The primary objective of this study is to determine the peak pressure, contact pressure, and impulse at the base of ...
Matheis Erika A EA Graduate Student, Orthopaedic Research Laboratory, Departments of Biomedical Engineering and Orthopaedic Surgery, Virginia Commonwealth University, Richmond, - - 2014
Adult acquired flatfoot deformity is a degenerative disease causing medial arch dysfunction. Surgical correction has typically involved tendon reconstruction with calcaneal osteotomy; however, the postoperative changes have not been fully characterized. The present study assessed the success of surgical correction of Stage IIb adult acquired flatfoot deformity through changes in ...
Sartor Cristina D - - 2014
Foot musculoskeletal deficits are seldom addressed by preventive medicine despite their high prevalence in patients with diabetic polyneuropathy. To investigate the effects of strengthening, stretching, and functional training on foot rollover process during gait. A two-arm parallel-group randomized controlled trial with a blinded assessor was designed. Fifty-five patients diagnosed with ...
Plom W W Centre for Sport and Exercise Sciences, School of Biological Sciences, University of Essex, Essex, - - 2014
The aim of this study was to test the effect different unstable footwear constructions have on centre of pressure motion when standing. Sixteen young female volunteers were tested in five conditions, three unstable footwear (Reebok Easy-Tone™, FitFlop™ and Skechers Shape-Ups™), a standard shoe and barefoot in a randomised order. Double ...
Drevelle Xavier X Institution Nationale des Invalides Centre d'Etude et de Recherche sur l'Appareillage des Handicapés, BP 50719, 57147 Woippy Cedex, France. Electronic address: - - 2014
Vaulting is a gait compensatory mechanism used by transfemoral amputees to assist toe clearance during the prosthetic swing phase. It is defined by a plantar flexion of the contralateral ankle during the single-limb support phase. The aim of the study is to propose a method to quantify vaulting of transfemoral ...
Broholm Rikke R Department of Clinical Physiology and Nuclear Medicine, Bispebjerg and Frederiksberg Hospital, University of Copenhagen , - - 2014
Background. Measurement of the ankle and toe pressures are often performed using a plethysmograph, compression cuffs and a strain gauge. Usually, the strain gauge contains mercury but other alternatives exist. From 2014, the mercury-containing strain gauge will no longer be available in the European Union. The aim of this study ...
Kluger Anna Katharina - - 2014
Abstract Background: The aim of our study was to introduce a so-called "neutral shoe" as a tool to assess reference values for dynamic pedobarographic investigations. Materials and methods: Twelve healthy volunteers were asked to participate. During the first trial the participants were asked to walk with a neutral shoe (Breidbach, ...
Hetsroni Iftach I Department of Orthopedic Surgery, Meir General Hospital, Kfar Saba, - - 2014
Plantar pressure abnormalities after open reduction with internal fixation (ORIF) of intra-articular calcaneal fractures have been observed previously, but high-grade fractures were not selectively investigated and follow-up times were shorter than 2 years. The purpose of this study was to characterize plantar pressure anomalies in patients with exclusively high-grade calcaneal ...
Sadler Sean - - 2014
Measurement of toe and ankle blood pressure is commonly used to evaluate peripheral vascular status, yet the pre-test rest period is inconsistent in published studies and among practitioners, and could affect results. The aim of this systematic review is to evaluate all research that has investigated the effect of different ...
Liu Shenggang S National Key Laboratory of Shock Wave and Detonation Physics, Institute of Fluid Physics, Chinese Academy of Engineering Physics, Mianyang, Sichuan 621900, - - 2014
A novel and simple method based on optical-fiber frequency domain interferometer to measure the deformation of diamond anvils under high pressure is presented. The working principle and application examples are given in this paper. The deformation of diamond anvils is obtained up to 37.7 GPa, our results verify that the ...
Hatam N N Clinic for Cardiac, Thoracic and Vascular Surgery, Aachen University hospital RWTH - - 2014
Purpose: Noninvasive pressure support ventilation is intended to relieve the load on respiratory muscles and to prevent exhaustion. This includes continuous positive airway pressure (CPAP) as well as pressure support ventilation (PSV). Speckle tracking echocardiography (STE) allows quantification of tissue deformation by tracing characteristic grayscale patterns, independent of the acquisition ...
Malavi Pallavi S PS High Pressure and Synchrotron Radiation Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, - - 2014
Optimally doped iron-chalcogenide superconductor Fe1.03Se0.5Te0.5 has been investigated under high pressures using synchrotron-based x-ray diffraction and mid-infrared reflectance measurements at room temperature. The superconducting transition temperature (Tc) of the same sample has been determined by temperature-dependent resistance measurements up to 10 GPa. The tetragonal phase (P4/nmm) is found to exist in ...
Wellenkotter J J Health Professions, University of Wisconsin-La Crosse, La Crosse, WI, United - - 2014
Our purpose was to evaluate effects of cadence manipulation on plantar loading during running. Participants (n=38) ran on a treadmill at their preferred speed in 3 conditions: preferred, 5% increased, and 5% decreased while measured using in-shoe sensors. Data (contact time [CT], peak force [PF], force time integral [FTI], pressure ...
Farzadi Maede M 1Department of Prosthetics and Orthotics, University of Social Welfare and Rehabilitation Sciences, Tehran, Islamic Republic of - - 2014
Background:Higher plantar pressures at the medial forefoot are reported in hallux valgus. Foot orthoses with medial arch support are considered as an intervention in this pathology. However, little is known about the effect of foot orthoses on plantar pressure distribution in hallux valgus.Objectives:To investigate the effect of a foot orthosis ...
Fourchet François F ASPIRE Health Centre - ASPETAR, National Sports Medicine Programme, Doha, Qatar. Electronic address: - - 2014
This study aimed to determine adjustments in spring-mass model characteristics, plantar loading and foot mobility induced by an exhaustive run. Within-participants repeated measures. Eleven highly-trained adolescent middle-distance runners ran to exhaustion on a treadmill at a constant velocity corresponding to 95% of velocity associated with VO2max (17.8±1.4kmh(-1), time to exhaustion=8.8±3.4min). ...
Jeans Kelly A KA *Texas Scottish Rite Hospital for Children, Dallas, TX †Arnold Palmer Children's Hospital, Orlando, - - 2014
Relapses following nonoperative treatment for clubfoot occur in 29% to 37% of feet after initial correction. One common gait abnormality is supination and inversion of the foot caused by an imbalance of the anterior tibialis tendon muscle. The purpose of this study was to determine if plantar pressures are normalized ...
Griebert Maggie C MC Emory University, Atlanta, GA, USA. Electronic address: - - 2014
Medial tibial stress syndrome (MTSS) is an overuse injury occurring among the physically active. Linked to increased strain on the medial tendons of the ankle, studies emphasize controlling medial foot loading in the management of this condition. Kinesio taping (KT) has gained popularity for treating musculoskeletal pathologies; however, its effect ...
Høyer C C Department of Clinical Physiology, Viborg Regional Hospital, Viborg, Denmark; Department of Health Science and Technology, Aalborg University, Aalborg, Denmark. Electronic address: - - 2014
To assess the intra- and inter-observer variation in laser Doppler flowmetry curve reading for measurement of toe and ankle pressures. A prospective single blinded diagnostic accuracy study was conducted on 200 patients with known or suspected peripheral arterial disease (PAD), with a total of 760 curve sets produced. The first ...
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