Search Results
Results 51 - 100 of 2397
1 2 3 4 5 6 7 8 9 10 >
Tennant Ingrid A IA From the Tropical Medicine Research Institute (D.S.T., M.S.B.), Departments of Surgery, Radiology, Anaesthesia, and Intensive Care (I.A.T., A.T.B.), Medicine (Cardiology) (E.E.C., A.P.C.), and UWI Solutions for Developing Countries (T.E.F.), University of the West Indies, Mona, Kingston, Jamaica; Institute Biomedical Technology, Ghent University, Gent, Belgium (J.K., P.S.); MRC Lifecourse Epidemiology Unit (C.O.) and DOHAD Division (M.A.H.), University of Southampton, Southampton, United Kingdom; Centre for Human Evolution, Adaptation, and Disease, Liggins Institute, University of Auckland, Auckland, New Zealand (P.D.G.); and Division of Diabetes, Cardiovascular Medicine, and Nutrition, King's College and King's Health Partners, London, United Kingdom - - 2014
Malnutrition below 5 years remains a global health issue. Severe acute malnutrition (SAM) presents in childhood as oedematous (kwashiorkor) or nonoedematous (marasmic) forms, with unknown long-term cardiovascular consequences. We hypothesized that cardiovascular structure and function would be poorer in SAM survivors than unexposed controls. We studied 116 adult SAM survivors, ...
Chen Zhang Z Department of Pediatric Cardiology,Beijing Anzhen Hospital,Capital Medical University,Beijing - - 2014
Objective To assess the accuracy of cardiac output(CO)measured by transpulmonary thermodilution technique(TPTD)and explore the validity of intrathoracic blood volume index(ITBVI)for assessment of circulatory volume status. Methods Ten immature pigs with a mean weight of(20.6±1.9)kg were studied during the conditions including normovolemia,hypervolemia,and hypovolemia. Simultaneous CO was measured in each condition using ...
Sanchez Ruderisch H H Charite - University Medicine Berlin, Center for Cardiovascular Research, Berlin, - - 2014
Sex differences have been observed in patient with aortic stenosis, women develop a more concentric form of myocardial hypertrophy than men and men have a stronger activation of profibrotic genes. Transverse aortic constriction induces more ventricular dilatation and fibrosis in male than in female mice which is partially mediated by ...
Melik Z Z University of Ljubljana, Faculty of Medicine, Insitute of Physiology, Ljubljana, - - 2014
Postocclusive reactive hyperaemia (PORH) is one of the provocation tests for registering differences in vasodilation capabilities in healthy and diseased subjects. One of the hypotheses of essential hypertension is that endothelial dysfunction due to reduced availability of nitric oxide plays a key role in initiation, development and progression of the ...
Maarman G J GJ University of Cape Town, Hatter Cardiovascular Research Institute, Department of Medicine, Cape Town, South - - 2014
Pulmonary arterial hypertension (PAH) is a disorder characterized by elevated pulmonary arterial pressure which leads to cardiac hypertrophy and dysfunction. Current treatments have marginal impact and additional therapies are required. Melatonin is a natural product shown to be cardioprotective against hypertension and myocardial ischemia. We propose that melatonin treatment may ...
Snijder P M PM Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the - - 2014
Hypertension is an important mediator of cardiac damage and remodelling. Hydrogen sulfide (H2 S) is an endogenously produced gasotransmitter with cardioprotective properties. However, clinical use is not within reach. We therefore investigated the protective effects of sodium thiosulfate (STS), a clinically applicable H2 S donor substance, in Angiotensin II (Ang ...
Laranjo Sérgio S 1Institute of Physiology and Cardiovascular Autonomic Lab, Faculty of Medicine of - - 2014
Around 15% of children and adolescents experience at least one episode of syncope until adulthood. Excluding cardiac disease, the majority of syncopes are of reflex origin and benign in nature. In this situation, a tilt test is conducted to reproduce symptoms and to evaluate cardiovascular adaptations to orthostatism, but its ...
Leung Joanne Y T JY Department of Anesthesiology, Pharmacology & Therapeutics, Faculty of Medicine, 2176 Health Sciences Mall, The University of British Columbia, Vancouver, British Columbia, Canada, V6T - - 2014
Treatment with antipsychotics is associated with adverse cardiovascular effects such as orthostatic hypotension and arrhythmias. Despite the higher prevalence of cardiovascular complications in patients with schizophrenia, the effects of antipsychotic drugs on vascular tone and cardiac contractility have received little attention. In order to better understand the cardiovascular effects of ...
Adedayo Pelumi P Department of Pediatrics, Penn State Hershey Pediatric Cardiovascular Research Center, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, PA, - - 2014
The objective of this study was to evaluate the pump performance of the novel diagonal Medos Deltastream DP3 diagonal pump (MEDOS Medizintechnik AG, , Stolberg, Germany) under nonpulsatile to pulsatile mode with varying differential speed values in a simulated pediatric extracorporeal life support system. The experimental circuit consisted of a ...
Yun So Hui SH Department of Anesthesiology and Pain Medicine, Jeju National University School of Medicine, Aran 13gil 15, Jeju, Jeju Special Self-governing Province, 690-767, Republic of - - 2014
Controlled hypotension (CH) is a well-established technique to decrease blood loss and improve surgical visibility. Although nitroprusside and remifentanil have been safely and effectively used for this purpose, the hemodynamic changes that occur during CH are unclear. This study compared the effects of nitroprusside and remifentanil on hemodynamics using a ...
Badagliacca Roberto R Departments of a?>Cardiovascular and Respiratory Science. Electronic address: - - 2014
Right ventricular (RV) dyssynchrony has been described in pulmonary arterial hypertension (PAH), but no evidence is available on its morphologic determinants and its effect on systolic function. The aim of this study was to evaluate the morphologic determinants of RV dyssynchrony by echocardiographic and cardiac magnetic resonance imaging and its ...
Moore-Morris Thomas - - 2014
Activation and accumulation of cardiac fibroblasts, which result in excessive extracellular matrix deposition and consequent mechanical stiffness, myocyte uncoupling, and ischemia, are key contributors to heart failure progression. Recently, endothelial-to-mesenchymal transition (EndoMT) and the recruitment of circulating hematopoietic progenitors to the heart have been reported to generate substantial numbers of ...
Dschietzig Thomas Bernd TB Immundiagnostik AG, Stubenwaldallee 8a, 64625, Bensheim, Germany, - - 2014
Acute heart failure (AHF) syndrome, characterized by pulmonary and/or venous congestion owing to increased cardiac filling pressures with or without diminished cardiac output, is still associated with high post-discharge mortality and hospitalization rates. Many novel and promising therapeutic approaches, among them endothelin-1, vasopressin and adenosine antagonists, calcium sensitization, and recombinant ...
Friess Stuart H SH St. Louis Children's Hospital Washington University in St. Louis School of Medicine Department of Pediatrics 660 S. Euclid Avenue, St. Louis MO 63110. Electronic address: - - 2014
Advances in cardiopulmonary resuscitation (CPR) have focused on the generation and maintenance of adequate myocardial blood flow to optimize the return of spontaneous circulation and survival. Much of the morbidity associated with cardiac arrest survivors can be attributed to global brain hypoxic ischemic injury. The objective of this study was ...
Rizzi Elen E Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, - - 2014
Hypertension induces left ventricular hypertrophy (LVH) by mechanisms involving oxidative stress and imbalanced cardiac matrix metalloproteinase (MMP) activity. We hypothesized that β1-adrenergic receptor blockers with antioxidant properties (nebivolol) could reverse hypertension-induced LVH more effectively than conventional β1-blockers (metoprolol) when used at doses that exert similar antihypertensive effects. Two kidney one ...
Crispi Fàtima F BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Deu), IDIBAPS, University of Barcelona, and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, - - 2014
-Fetal growth restriction (FGR) is associated with global adverse cardiac remodeling in utero and increased cardiovascular mortality in adulthood. Prenatal myocardial deformation has not been evaluated in FGR so far. We aimed to comprehensively evaluate prenatal cardiac remodeling in FGR including myocardial deformation imaging. -Echocardiography was performed in 37 consecutive ...
Surgit Ozgur O Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Department of Cardiology , Istanbul , - - 2014
Objective. Left ventricular (LV) hypertrophy (LVH) predicts increased mortality in part due to an elevated incidence of sudden cardiac death in hypertension. The aim of the present study was to investigate the relation of microvolt T-wave alternans (MTWA) with different LV geometric patterns in patient with sustained hypertension. Methods. This ...
Simons Ap A Deptartment of Cardiothoracic Surgery, Maastricht University Medical Centre and Cardiovascular Research Institute Maastricht, Maastricht, the Netherlands - - 2014
The aim of this study was to examine the hydrodynamic performance and gaseous microemboli (GME) activity of two centrifugal pumps for possible use in low-flow extracorporeal CO2 removal. The performance of a Rotassist 2.8 and a Rotaflow 32 centrifugal pump (Maquet Cardiopulmonary AG, Hirrlingen, Germany) was evaluated in a water-glycerine ...
Savalia Krupa K Department of Cellular and Integrative Physiology, University of Nebraska Medical - - 2014
Excessive production of superoxide (O2(●-)) in the central nervous system has been widely implicated in the pathogenesis of cardiovascular diseases, including chronic heart failure and hypertension. In an attempt to overcome the failed therapeutic impact of currently available antioxidants in cardiovascular disease, we developed a nanomedicine-based delivery system for the ...
Krishnaveni G V GV Epidemiology Research Unit, CSI Holdsworth Memorial Hospital, Mysore, India; *Centre for Cardiovascular Imaging, UCL Institute of Child Health, London, UK; Diabetes Unit, KEM Hospital Research Centre, Pune, India;Department of Psychology, University of Trier, Germany; St. Johns Research Institute, Bangalore, India; and MRC Lifecourse Epidemiology Unit, Southampton General Hospital, Southampton, UK. Correspondence to: Dr GV Krishnaveni, Epidemiology Research Unit, CSI Holdsworth Memorial Hospital, PO Box 38, Mandi Mohalla, Mysore 570 021, India. - - 2014
To test the Trier Social Stress Test for children (TSST-C) in a cohort of Indian adolescents. Cohort study. Holdsworth Memorial Hospital, Mysore, India. Adolescent children (N=273, 134 males; mean age 13.6 yrs) selected from an ongoing birth cohort; 269 completed the test. Performance of 5-minutes each of public- speaking and ...
Mosing Martina M Division of Anaesthesiology, Equine Department, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland, - - 2014
The aim of this study was to test the effect of cardiac output (CO) and pulmonary artery hypertension (PHT) on volumetric capnography (VCap) derived-variables. Nine pigs were mechanically ventilated using fixed ventilatory settings. Two steps of PHT were induced by IV infusion of a thromboxane analogue: PHT25 [mean pulmonary arterial ...
Zafar Haroon H Tissue Optics & Microcirculation Imaging Facility, National University of Ireland, - - 2014
Frequency domain optical coherence tomography (FD-OCT) provides cross-sectional images of coronary arteries and deployed stents with micron resolution and measures lumen dimensions with excellent reproducibility. FD-OCT combined with a blood flow resistances model can overcome many limitations of conventional measures of stenosis severity based on quantitative coronary angiography (QCA) and ...
Molcan L L Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University Bratislava, Bratislava, Slovak Republic. - - 2014
Disturbed circadian activity of the sympathetic system may be involved in negative consequences of chronodisruption on the cardiovascular system. We studied daily changes in pressure response to adrenergic stimulation in rats exposed to repeated phase advance shifts (PAS) of light/dark (LD) regimen. Blood pressure (BP), heart rate (HR) and locomotor ...
Alian Aymen A AA Department of Anesthesiology, Yale University School of Medicine, 333 Cedar Street, PO Box 208051, New Haven, CT 06520-8051, - - 2014
Lower body negative pressure (LBNP) creates a reversible hypovolemia by sequestrating blood volume in the lower extremities. This study sought to examine the impact of central hypovolemia on peripheral venous pressure (PVP) waveforms in spontaneously breathing subjects. With IRB approval, 11 healthy subjects underwent progressive LBNP (baseline, -30, -75, and -90 mmHg ...
Andersen L J LJ Department of Cardiology, Roskilde Hospital, Roskilde, Denmark; Department of Cardiology, Gentofte University Hospital, Hellerup, - - 2014
We investigated the effects of 3 and 6 months of regular football training on cardiac structure and function in hypertensive men. Thirty-one untrained males with mild-to-moderate hypertension were randomized 2:1 to a football training group (n = 20) and a control group receiving traditional recommendations on healthy lifestyle (n = 11). Cardiac measures were ...
Kilgannon J Hope JH 1Department of Emergency Medicine, Cooper University Hospital, Camden, NJ. 2Department of Emergency Medicine, The University of Mississippi Medical Center, Jackson, MS. 3Division of Critical Care Medicine, Department of Medicine, Cooper University Hospital, Camden, - - 2014
Guidelines for post-cardiac arrest care recommend blood pressure optimization as one component of neuroprotection. Although some retrospective clinical studies suggest that postresuscitation hypotension may be harmful, and laboratory studies suggest that a postresuscitation hypertensive surge may be protective, empirical data are few. In this study, we prospectively measured blood pressure ...
Kawashiri Masa-Aki MA Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, 920-8641, - - 2014
A line of epidemiological studies suggests that the accumulation of coronary risk factors promotes the progression of coronary atherosclerosis. Recent clinical studies showed that aggressive low-density lipoprotein (LDL) cholesterol-lowering therapy using statins could regress coronary atheroma and reduce major cardiovascular events. Additionally, therapy that controlled amlodipine-based blood pressure reduced major ...
Hillman Stan S SS Portland State University, United States; - - 2014
Amphibians have a single ventricle and common conus arteriosus that produces an equal pressure to the parallel pulmocutaneous and systemic vascular circuits. The distribution of blood flows between the pulmocutaneous (Qpul) and systemic (Qsys) circuits (net cardiac shunt) vary with a number of environmental conditions and behaviours; although autonomic regulation ...
Poole Aaron T AT Maternal-Fetal Medicine Division, Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, United States. Electronic address: - - 2014
Lactation is associated with reduction in maternal metabolic disease and hypertension later in life; however, findings in humans may be confounded by socioeconomic factors. We sought to determine the independent contribution of lactation on cardiovascular parameters and adiposity in a murine model. Following delivery, CD-1 female mice were randomly divided ...
Goodwill Adam G AG Department of Cellular & Integrative Physiology, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN, 462025111, - - 2014
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that has been shown to have hemodynamic and cardioprotective capacity in addition to its better characterized glucoregulatory actions. Because of this, emerging research has focused on the ability of GLP-1 based therapies to drive myocardial substrate selection, enhance cardiac performance and regulate heart ...
Hammad Sally S The University of - - 2014
Heart failure is the common and final end point of cardiovascular disease. Seventy four percent of congestive heart failure patients also suffer from hypertension. Genome wide association studies (GWAS) have recently identified mutations in the ATP2B1 gene as having a strong association with hypertension risk. The ATP2B1 gene encodes the ...
Sahmeddini Mohammad Ali MA Shiraz Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, - - 2014
Context-Attenuating postreperfusion syndrome during orthotopic liver transplant is very important for transplant anesthesiologists because of the syndrome's complications. Oxygen-derived free radicals play an important role in the genesis of postreperfusion syndrome, but the effect of mannitol (a free radical scavenger) on attenuating the syndrome is unclear.Objectives-To investigate the effectiveness of ...
Lee Eveline E University Hospital of - - 2014
Preload reduction during haemodialysis causes change in cardiac filling and contractility. This can be accurately assessed using standard echocardiography. We hypothesise that simple ECG parameters approximate Echo derived measurements and can be used as an initial tool. Thirty subjects (Age 59 ± 18 years, 35% female, LVEF 64 ± 6%, ...
Finegold Judith J International Centre for Circulatory Health, National Heart and Lung - - 2014
Acute haemodynamic measurements can be used for AV delay (AVD) optimisation of cardiac resynchronisation therapy (CRT). It is uncertain whether non-invasive measurements are as reliable as those measured invasively. 37 patients with CRT-P or CRT-D device (86% male, mean age 64 years) had AVD optimisation performed using both invasive and ...
Zoerner Frank F From the Department of Operative and Intensive Care Medicine (F.Z.), Hallands Hospital Halmstad, Halmstad; and Department of Surgical Sciences/Anaesthesiology and Intensive Care (E.S.), Faculty of Medicine, Uppsala University, Uppsala, - - 2014
Supplemental digital content is available in the text. The aim of this experimental study was to compare survival and hemodynamic effects of a low-dose amiodarone and vasopressin compared with vasopressin in hypovolemic cardiac arrest model in piglets. Eighteen anesthetized male piglets (with a weight of 25.3 [1.8] kg) were bled ...
You Beian B Department of Geriatrics, Qilu Hospital of Shandong University; Shandong Provincial Key Laboratory of Cardiovascular Proteomics, Jinan, Shandong 250012, - - 2014
Ouabain is a mammalian adrenocortical hormone that is involved in the pathogenesis of hypertension by inhibiting Na-K ATPase activity. It also participates in a variety of kinase-mediated signaling pathways associated with Na-K ATPase. Previous studies have shown that ouabain can cause cardiac remodeling independent of elevated blood pressure and that ...
Bae Joon-Ho JH Department of Emergency Medicine and Institute of Clinical Science, Kangwon National University Hospital, School of Medicine, Kangwon National University, Chuncheon, - - 2014
Defibrillation is no longer universally recommended as initial intervention for the reversal of ventricular fibrillation (VF) after a prolonged and untreated cardiac arrest. We sought to examine this issue in an animal model where a prolonged untreated VF was induced. The aim of this study was to investigate the potential ...
Perry Blake G BG School of Sport and Exercise, Massey University, Palmerston North, New - - 2014
Hypercapnia impairs cerebrovascular control during rapid changes in blood pressure (BP); however, data concerning the effect of hypercapnia on steady state, nonpharmacological increases in BP is scarce. We recruited fifteen healthy volunteers (mean ± SD: age, 28 ± 6 years; body mass, 77 ± 12 kg) to assess the effect ...
Bianchi Giorgia G Division of Internal Medicine and Nephrology, Ospedale la Carità, Locarno, - - 2014
Clinical experience and experimental data suggest that intradialytic hemodynamic profiles could be influenced by the characteristics of the dialysis membranes. Even within the worldwide used polysulfone family, intolerance to specific membranes was occasionally evoked. The aim of this study was to compare hemodynamically some of the commonly used polysulfone dialyzers ...
Samuel Chrishan S CS From the Department of Pharmacology, Monash University, Melbourne, Victoria, Australia (C.S.S., H.B., J.Y.C., R.E.W., S.G.R.); Neuropeptides Division, Florey Institute of Neuroscience and Mental Health (C.S.S.) and Department of Biochemistry and Molecular Biology (C.S.S.), University of Melbourne, Melbourne, Victoria, Australia; Department of Nephrology, Royal Melbourne Hospital, Melbourne, Victoria, Australia (T.D.H.); and Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Melbourne, Victoria, Australia (T.D.H.). chrishan.samuel@monash.edu - - 2014
Relaxin is a naturally occurring peptide hormone that mediates systemic hemodynamic and renal adaptive changes during pregnancy and abrogates aberrant scar tissue formation (fibrosis) in diverse pathogeneses. However, its efficacy relative to renin-angiotensin system blockade, the most effective antifibrotic strategy currently available, is not known. We compared the individual versus ...
Moret Enrique E Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain - - 2014
Maintaining vascular barrier competence, preventing interstitial edema, and keeping microcirculation intact is crucial to achieve an optimal outcome in cardiopulmonary bypass surgery (CPB). Blood contact with roller pumps and foreign surfaces during CPB induces shear stress and a pressure drop across the pump boot that leads to transient systemic activation ...
Brar Somjot S SS Department of Cardiology, Kaiser Permanente, Los Angeles, CA, USA; Regional Cardiac Cath Lab, Kaiser Permanente, Los Angeles, CA, USA; Department of Research and Evaluations, Kaiser Permanente, Pasadena, CA, USA. Electronic address: - - 2014
The administration of intravenous fluid remains the cornerstone treatment for the prevention of contrast-induced acute kidney injury. However, no well-defined protocols exist to guide fluid administration in this treatment. We aimed to establish the efficacy of a new fluid protocol to prevent contrast-induced acute kidney injury. In this randomised, parallel-group, ...
Mancia Giuseppe G From the IRCCS Istituto Auxologico Italiano, Milano, Italy (G.M.); Clinica Medica, Dipartimento di Scienze della Salute, Università Milano-Bicocca, Monza (Monza e Brianza), Italy (G.M., G.G.); and IRCCS Multimedica, Sesto San Giovanni, Milano, Italy (G.G.). - - 2014
Physiological studies have long documented the key role played by the autonomic nervous system in modulating cardiovascular functions and in controlling blood pressure values, both at rest and in response to environmental stimuli. Experimental and clinical investigations have tested the hypothesis that the origin, progression, and outcome of human hypertension ...
Vitacca Michele M Respiratory Rehabilitation Division, Salvatore Maugeri Foundation IRCCS, Lumezzane, (BS), Italy. Electronic address: - - 2014
To evaluate heart rate variability (HRV), hemodynamics, mechanics, dyspnea and blood gases following different mechanical ventilation (MV) settings. No study has evaluated physiological changes during T-piece trials following different MV settings. In 8 COPD patients on prolonged MV we applied in random order two MV settings: i) pressure support (PS) ...
Dyson A A Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, - - 2014
In clinical practice, global oxygen delivery (DO2) is often considered as a whole; however pathological and adaptive responses after a decrease in individual constituents of the DO2 equation (cardiac output, haemoglobin, oxyhaemoglobin saturation) are likely to be diverse. We hypothesized that an equivalent decrease in DO2 after reductions in each ...
Teman Nicholas R NR Department of Surgery, University of Michigan Health System, Extracorporeal Life Support Laboratory, Ann Arbor, - - 2014
Centrifugal pumps are used increasingly for temporary mechanical support for the treatment of cardiogenic shock. However, centrifugal pumps can generate excessive negative pressure and are afterload sensitive. A previously developed modified roller pump mitigates these limitations both in vitro and in preliminary animal experiments. We report the results of intermediate-term testing ...
Zgoła Katarzyna - - 2014
Anaesthetic drugs and internal electrical shock may alter haemodynamic status of patients undergoing implantable cardioverter-defibrillator (ICD) testing. Comparative data on the mechanisms of etomidate and propofol-induced changes in haemodynamic parameters are inconsistent. Also the effects of ICD shock on haemodynamics have not been extensively studied. To compare haemodynamic effects of ...
Fine Leon G LG Department of Biomedical Sciences, Cedars-Sinai Medical Center and University of California Los Angeles, Los Angeles, Calif., - - 2014
Ernest Henry Starling laid the groundwork for our modern understanding of how the interstitial fluid, which he referred to as 'lymph', is regulated. Together with his colleague, William Bayliss, he provided the crucial insight into how fluid is driven out of the capillary to form interstitial fluid. That was to ...
Pereira Dos Santos Marcos Antonio MA 1Departamento de Biofísica e Fisiologia, Campus Universitário Ministro Petrônio Portella, Universidade Federal do Piauí , Teresina-PI , - - 2014
This review evaluates the documented cardiovascular functioning among anabolic-androgenic steroid (AAS) users. AAS users manifest a reduction in HDL cholesterol, increased inflammatory markers, and oxidative stress. Strong evidence associating AAS use with blood pressure at hypertensive levels, as well as hypertrophy and cardiac dysfunction has also been reported. Both epidemiological ...
Reniguntala M S J MS Department of Pharmaceutical Sciences, Midwestern University Chicago College of Pharmacy, Downers Grove, IL, - - 2014
Centhaquin is a compound that produces hypotension and bradycardia in higher doses and resuscitation in lower doses. It is water insoluble, and is unsuitable for intravenous use. We prepared the citrate salt of centhaquin and evaluated its cardiovascular efficacy vs. centhaquin. Centhaquin citrate was prepared and characterized; its purity was ...
1 2 3 4 5 6 7 8 9 10 >