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Schlader Zachary J ZJ Institute for Exercise and Environmental - - 2014
During normothermia, a reduction in near infrared spectroscopy (NIRS) derived tissue oxygen saturation (SO2) is an indicator of central hypovolemia. Hyperthermia increases skin blood flow and reduces tolerance to central hypovolemia, both of which may alter the interpretation of tissue SO2 during central hypovolemia. This study tested the hypothesis that ...
Cheriyan Thomas T Burlington, Mass.; and Taoyuan, Taiwan From the Department of Plastic Surgery, Lahey Hospital and Medical Center, the Department of Pathology, Molecular Cardiology Research Institute, Tufts School of Medicine; and the Department of Plastic Surgery, Chang Gung Memorial Hospital, - - 2014
Autologous fat grafting has been widely used in reconstructive and cosmetic surgery. Harvesting techniques play a key role in graft viability and outcomes. The authors investigated the effect of harvest pressure on adipocyte survival and viability of the surviving cells. Abdominal lipoaspiration was performed at high pressure (-760 mmHg) and ...
Mrad Rachelle R UR Technologies et Valorisation Alimentaires, Centre d'Analyses et de Recherche, Faculté des Sciences, Université Saint-Joseph, B.P. 11-514 - Riad El Solh, Beirut, Lebanon. Electronic address: - - 2014
A new process, Intensification of Vaporization by Decompression to the Vacuum (IVDV), is proposed for texturizing purple maize. It consists in exposing humid kernels to high steam pressure followed by a decompression to the vacuum. Response surface methodology with three operating parameters (initial water content (W), steam pressure (P) and ...
Johnston Blair F - - 2014
This article details the exploration of perdeuterated acrylic acid at high pressure using neutron diffraction. The structural changes that occur in acrylic acid-d4 are followed via diffraction and rationalised using the Pixel method. Acrylic acid undergoes a reconstructive phase transition to a new phase at ~0.8 GPa and remains molecular ...
Fang Hong H Department of Earth Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EQ, - - 2014
By exploring a simple model of a negative thermal expansion (NTE) system, we introduce a phenomenological expression to describe the temperature dependence of the pressure-induced softening in NTE structures.
Khouri Roger K RK Miami, Fla.; Ann Arbor, Mich.; Houston, Texas; and Verona, Italy From the Miami Breast Center; Herbert Wertheim College of Medicine at Florida International University; the University of Michigan Medical School; Baylor College of Medicine; and the University of - - 2014
This article describes the theory and principles behind the authors' success in megavolume (250-ml range) autologous fat transfer to the breasts. When large volumes are grafted into a tight space, the interstitial fluid pressure increases to impair capillary blood flow and the crowded graft droplets coalesce into lakes, with poor ...
Fuhrmann Sindy S Otto Schott Institute, University of Jena, 07743 Jena, - - 2014
Understanding the response of glasses to high pressure is of key importance for clarifying energy-dissipation and the origin of material damage during mechanical load. In the absence of shear bands or motile dislocations, pressure-induced deformation is governed by elastic and inelastic structural changes which lead to compaction of the glass ...
Vlaisavljevich Eli - - 2014
Histotripsy is an ultrasound ablation method that depends on the initiation and maintenance of a cavitation bubble cloud to fractionate soft tissue. This paper studies how tissue properties impact the pressure threshold to initiate the cavitation bubble cloud. Our previous study showed that shock scattering off one or more initial ...
Kruk Zbigniew A ZA School of Animal and Veterinary Sciences, The University of Adelaide, Roseworthy, SA 5371, - - 2014
This study was conducted to evaluate the combined effect of high pressure (HP) with the addition of soy sauce and/or olive oil on the quality and safety of chicken breast meats. Samples were cut into 100 g pieces and 10% (w/w) of soy sauce (SS), 10% (w/w) of olive oil ...
Lenneman Carrie G CG Department of Medicine, Vanderbilt University School of Medicine, Nashville 37232, TN, USA ; Department of Medicine, University of Louisville School of Medicine, Louisville, KY 40292, - - 2014
HER2 antagonists (anti-HER2; e.g., trastuzumab and lapatinib) are effective in treating an aggressive form of breast cancer (BC), but can cause cardiotoxicity due to the disruption in neuregulin (NRG)/HER2+ ligand receptor signalling. The recent data show that NRG-HER2 receptors located in the medulla oblongata are important regulators of vasomotor tone. ...
Yu Xiaodong X College of Water Conservancy and Hydropower Engineering, Hohai University, Nanjing 210098, - - 2014
Based on the theory of hydraulic transients and the method of characteristics (MOC), a mathematic model of the differential surge tank with pressure-reduction orifices (PROs) and overflow weirs for transient calculation is proposed. The numerical model of hydraulic transients is established using the data of a practical hydropower station; and ...
Thomsen Maria M Niels Bohr Institute, University of Copenhagen, Copenhagen, Denmark; Novo Nordisk A/S, Hillerød, - - 2014
In this study we estimate the subcutaneous tissue counter pressure during drug infusion from a series of injections of insulin in type 2 diabetic patients using a non-invasive method. We construct a model for the pressure evolution in subcutaneous tissue based on mass continuity and the flow laws of a ...
Feistenauer Susan S Department of Comparative Medicine, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Ruhr-Universität Bochum, - - 2014
Animal allergens constitute a serious health risk in laboratory animal facilities. To assess possibilities for allergen reduction by technical and organizational measures, we studied personnel exposure to mouse urinary aeroallergens in an animal facility with a holding capacity of 30,000 cages. Short-term (2 h) and intermediate-term (12 h) stationary samples ...
Larson Jeffrey D JD Madison and Milwaukee, Wis. From the Department of Plastic Surgery, University of Wisconsin Medical School; and Department of Plastic Surgery, The Medical College of - - 2014
After reading this article, the participant should be able to: 1. Discuss the approach and rationale of pressure sore management, including specific techniques of bone biopsy and postoperative care resulting in a significant reduction in recurrence rates. 2. Develop a surgical plan for reconstructing defects of the perineum, taking into ...
Cheng Chris-Tin - - 2013
Lymphoedema of the arm is a potentially serious consequence of any axillary procedure performed during the management of breast cancer. In an attempt to reduce its incidence and severity, patients are instructed to avoid venepunctures and blood pressure measurements on the treated arm. These precautions are not possible in some ...
Wu W F - - 2013
In this study, iron reduction and concomitant biomineralization of a deep-sea iron reducing bacterium (IRB), Shewanella piezotolerans WP3, were systematically examined at different hydrostatic pressures (0.1, 5, 20, and 50 MPa). Our results indicate that bacterial iron reduction and induced biomineralization are influenced by hydrostatic pressure. Specifically, the iron reduction rate ...
Jordá Jose L - - 2013
The first pressure-induced solid-phase synthesis of a zeolite has been found through compression of a common zeolite, ITQ-29 (see scheme, Si yellow, O red). The new microporous structure, ITQ-50, has a unique structure and improved performance for propene/propane separation with respect the parent material ITQ-29.
de Groot J E - - 2013
Purpose: In x-ray mammography, flattening of the breast improves image quality and reduces absorbed dose. Current mammographic compression guidelines are based on applying a standardized force to each breast. Because breast size is not taken into consideration, this approach leads to large variations in applied pressure (force applied per unit ...
Lizhuo Chen - - 2013
Among various techniques enabling absolute measurements of ultrasound pressure, light refractive tomography (LRT) is so far the only one which is noninvasive, omnidirectional, and provides time-resolved results in pascals. By exploiting all these advantages, LRT shows suitability for investigations of ultrasound pressure fields, even in the case of adjacent medium ...
Theodor Michael - - 2013
We introduce a minimally invasive, implantable system that uses pulse transit time to determine blood pressure. In contrast to previous approaches, the pulse wave is detected by a photoplethysmographic (PPG) signal, acquired with high quality directly on subcutaneous muscle tissue. Electrocardiograms (ECG) were measured with flexible, implantable electrodes on the ...
Langrenne Christophe - - 2013
This paper presents an application of the data completion method (DCM) for vector intensity reconstructions. A mobile array of 36 pressure-pressure probes (72 microphones) is used to perform measurements near a planar surface. Nevertheless, since the proposed method is based on integral formulations, DCM can be applied with any kind ...
Hogg Peter - - 2013
Purpose: Compression is necessary in mammography to improve image quality and reduce radiation burden. Maximizing the amount of breast in contact with the image receptor (IR) is important. To achieve this, for the craniocaudal projection, there is no consensus within the literature regarding how the IR should be positioned relative ...
McNamara Maria E ME Department of Geology and Geophysics, Yale University, New Haven, CT 06520, USA. - - 2013
Fossil feathers often preserve evidence of melanosomes-micrometre-scale melanin-bearing organelles that have been used to infer original colours and patterns of the plumage of dinosaurs. Such reconstructions acknowledge that evidence from other colour-producing mechanisms is presently elusive and assume that melanosome geometry is not altered during fossilization. Here, we provide the ...
Levi Alessandro - - 2013
In this paper we present a new optical, flexible pressure sensor that can be applied as smart skin to a robot or to consumer electronic devices. We describe a mechano-optical transduction principle that can allow the encoding of information related to an externally applied mechanical stimulus, e.g., contact, pressure and ...
Hogg P P School of Health Sciences, University of Salford, Salford, UK. - - 2013
To perform a calibration study to provide data to help improve consistency in the pressure that is applied during mammography. Automatic readouts of breast thickness accuracy vary between mammography machines; therefore, one machine was selected for calibration. 250 randomly selected patients were invited to participate; 235 agreed, and 940 compression ...
Horvat Mario - - 2013
Enhancement of product properties of extruded starch based products can be achieved by incorporating health promoting oil into the matrix. In order to achieve a preferably high expansion with a homogeneous pore structure, the expansion mechanisms have to be understood. In our study, we applied a customized twin-screw extruder set ...
Antonova Mariya L - - 2012
OBJECTIVE: The oscillometric method is used in the medical practice for measurement of arterial blood pressure and, rarely, for estimation of arterial elasticity. In the previous paper of this series, the relations between arterial volume pulsations and volume-to-pressure curve (elastogram) were examined resolving the problem for evaluation of arterial volume ...
Tananuwong Kanitha K Dept. of Food Technology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. - - 2012
High-pressure inactivation of Salmonella Typhimurium DMST 28913, eating quality, and microstructure of pressurized raw chicken breast meat was determined. The inoculated samples (approximately 7 log CFU/g initial load) were processed at 300 and 400 MPa, using pressurized medium of 25 to 35 °C during pressurization. Weibull model was well fitted ...
Myers Kevin - - 2012
Growth of Listeria monocytogenes was evaluated for up to 182days after inoculation on ready-to-eat (RTE) sliced ham and turkey breast formulated with sodium nitrite (0 or 200ppm), sodium chloride (1.8% or 2.4%), and treated (no treatment or 600MPa) with high hydrostatic pressure (HHP). HHP at 600MPa for 3min resulted in ...
Kobori Hiroyuki H Department of Physiology, Tulane University Health Sciences Center, 1430 Tulane Avenue, #SL39, New Orleans, LA 70112-2699, USA. - - 2013
Activated intrarenal renin-angiotensin system plays a cardinal role in the pathogenesis of hypertension and chronic kidney disease. Angiotensinogen is the only known substrate for renin, which is the rate-limiting enzyme of the renin-angiotensin system. Because the levels of angiotensinogen are close to the Michaelis-Menten constant values for renin, angiotensinogen levels ...
Bidani Anil K AK Department of Medicine, Loyola University Chicago, - - 2012
Current therapeutic interventions to retard the progression of chronic kidney disease have yielded disappointing outcomes despite adequate renin-angiotensin system blockade. The parameters to gauge the adequacy of blood pressure control need to be reassessed because clinic blood pressure constitutes a poor gauge of such control. The biologically relevant parameter for ...
Najafipour Hamid - - 2012
BACKGROUND: Chronic kidney diseases lead to severe cardiovascular consequences such as hypertension and cardiac failure. Apelin, along with its receptor APJ have been shown to involve in cardiovascular functions including blood pressure (BP) lowering effect and also a positive inotropic effect on failing hearts. Therefore we investigated the effect of ...
Yang Jun - - 2012
Background: Tissue microarray (TMA) is a novel and useful tool to efficiently analyze gene expression in histological tissues. Aim: Cost-efficient and easy to use automated tissue arrayers will provide a better instrumentation to generate TMAs. Thus, we designed and produced our tissue microarrayer to meet these needs. Materials and Methods: ...
Shimosawa Tatsuo - - 2012
Salt-sensitive hypertension is closely related with natriuretic capacity of the kidney. Besides several genome-wide research reported candidate gene or gene polymorphism responsible for salt-sensitive hypertension, recently, several new factors for acquired salt-sensitive hypertension are reported. Among them, we have identified that rac1, a small GTPase, activates mineralocorticoid receptor in aldosterone-independent ...
Sheehan David - - 2012
The kidney helps to maintain low blood pressure in the human body, and impaired kidney function is a common attribute of aging that is often associated with high blood pressure (hypertension). Kidney-related pathologies are important contributors (either directly or indirectly) to overall human mortality. In comparison with other organs, kidney ...
Telfer Scott - - 2012
ABSTRACT: BACKGROUND: The design of foot and ankle orthoses is currently limited by the methods used to fabricate the devices, particularly in terms of geometric freedom and potential to include innovative new features. Additive manufacturing (AM) technologies, where objects are constructed via a series of sub-millimetre layers of a substrate ...
Cheung Perry - - 2012
In this paper, we present a simple procedure to incorporate commercially available external pressure transducers into existing microfluidic devices, to monitor pressure-drop in real-time, with minimal design modifications to pre-existing channel designs. We focus on the detailed fabrication steps and assembly to make the process straightforward and robust. The work ...
Chen Daian - - 2012
The pathogenesis of hypertension is multi-factorial, involving many of the systems contributing to blood pressure homeostasis including the vasculature, kidneys, central, and sympathetic nervous systems, along with various hormonal regulators. However, over the years, many studies have indicated a predominant importance of the kidney in blood pressure homeostasis and hypertension. ...
Smyth Andrew - - 2012
J Clin Hypertens (Greenwich). 2012;14:216-221. ©2012 Wiley Periodicals, Inc. The initial description of Page kidney, a form of renin-mediated hypertension, included athletes with renal subcapsular hematoma after flank trauma. Subsequently, nontraumatic etiologies were identified. In this study, the authors compare traumatic and nontraumatic causes of Page kidney. All cases with ...
Hultström Michael - - 2012
The spontaneously hypertensive rat (SHR) is one of the major models of hypertension. This article describes the current state of knowledge about the mechanism behind kidney damage in SHR in the context of human hypertension and hypertensive kidney disease. It will argue that hypertensive damage in the SHR is pressure-dependent ...
Rob Taal H - - 2012
BACKGROUND: Smaller kidneys with reduced number of nephrons in early life lead to impaired kidney function and risk for hypertension and chronic kidney disease. These associations might be partly explained by common genetic variation. AIMS: To assess the associations between common genetic variants, which have recently shown to be associated ...
Elfering Achim - - 2012
Global self-esteem was tested to predict quicker cardiovascular adaptation during stressful oral thesis presentation and faster habituation from the first to the second and third thesis presentations. Nineteen graduate students initially rated their global self-esteem and afterwards orally presented their theses proposals in 20-min presentations to their thesis supervisor and ...
Herrera Marcela - - 2012
Despite decades of study, the pathogenesis of essential hypertension remains obscure, but the kidney appears to play a central role. Technology for manipulation of the mouse genome has been immensely valuable in dissecting pathways involved in blood pressure control. This review summarizes recent studies employing this technology to understand signaling ...
Moerer Onnen - - 2012
New developments in mechanical ventilation have focused on increasing the patient's control of the ventilator by implementing information on lung mechanics and respiratory drive. Effort-adapted modes of assisted breathing are presented and their potential advantages are discussed. Adaptive support ventilation, proportional assist ventilation with load adjustable gain factors and neurally ...
Perna Alessandra F - - 2012
Hydrogen sulphide, H(2)S, is a gaseous compound involved in a number of biological responses, e.g. blood pressure, vascular function and energy metabolism. In particular, H(2)S is able to lower blood pressure, protect from injury in models of ischaemia-reperfusion and induce a hypometabolic state. In chronic kidney disease (CKD), low plasma ...
Utsumi Kouichi - - 2012
Chronic kidney disease (CKD) is defined as either kidney damage or an estimated glomerular filtration rate (eGFR) of less than 60 mL/min/1.73 m<sup>2</sup> for more than 3 months. Kidney damage is defined as pathological abnormalities or markers of damage, including abnormalities in blood or urine tests or imaging studies. CKD ...
Tien Joe - - 2012
This paper reports the effect of elevated pressure on the invasive phenotype of patterned three-dimensional (3D) aggregates of MDA-MB-231 human breast cancer cells. We found that the directionality of the interstitial pressure profile altered the frequency of invasion by cells located at the surface of an aggregate. In particular, application ...
Schlaich Markus P - - 2012
Increased central sympathetic drive is a hallmark of several important clinical conditions including essential hypertension, heart failure, chronic kidney disease, and insulin resistance. Afferent signaling from the kidneys has been identified as an important contributor to elevated central sympathetic drive and increased sympathetic outflow to the kidney and other organs ...
Pontzer Herman - - 2011
Ecomorphological analyses have identified a number of important evolutionary trends in vertebrate limb design, but the relationships between daily travel distance, locomotor ecology, and limb length in terrestrial animals remain poorly understood. In this paper I model the net rate of energy intake as a function of foraging efficiency, and ...
Dong Zhaohui - - 2011
In this study, two hydrazine derivatives, azobenzene and hydrazobenzene, were compressed in a diamond anvil cell at room temperature up to 28 GPa followed by decompression. In situ Raman spectroscopy was employed to monitor the pressure-induced structural evolutions. Azobenzene was found to undergo a phase transition at ∼10 GPa. Further ...
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