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Results 201 - 250 of 1590
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Linsler Stefan - - 2012
INTRODUCTION: LiquoGuard is a new device for intracranial pressure (ICP)-controlled drainage of cerebrospinal fluid (CSF). This present study evaluates the accuracy of ICP measurement via the LiquoGuard device in comparison with Spiegelberg. Thus, we compared data ascertained from simultaneous measurement of ICP using tip-transducer and tip-sensor devices. MATERIAL AND METHODS: ...
Varsos Georgios V GV Neurosurgical Unit, Department of Clinical Neurosciences, Division of Neurosurgery, Addenbrooke's Hospital, Cambridge, UK. - - 2013
Critical closing pressure (CCP) is the arterial blood pressure (ABP) at which brain vessels collapse and cerebral blood flow (CBF) ceases. Using the concept of impedance to CBF, CCP can be expressed with brain-monitoring parameters: cerebral perfusion pressure (CPP), ABP, blood flow velocity (FV), and heart rate. The novel multiparameter ...
Villar Rodrigo - - 2013
This study hypothesized that central and local reflex mechanisms affecting vascular conductance (VC) through the popliteal artery compensated for the reduction in muscle perfusion pressure (MPP) to maintain popliteal blood flow (PBF) during head-down tilt (35˚ HDT), but not in head-up tilt (45˚ HUT). Resting measurements were made on 15 ...
Weenink Robert P - - 2012
Cerebral arterial gas embolism (CAGE) is well known as a complication of invasive medical procedures and as a risk in diving and submarine escape. In the underwater environment, CAGE is caused by trapped air, which expands and leads to lung vessel rupture when ambient pressure decreases during ascent. Pressure decrease ...
Eley Karen A - - 2012
: In a small number of children with unicoronal synostosis, the phenotype is mild and the aesthetic benefit of surgical correction is potentially outweighed by surgical risk. Raised intracranial pressure, however, would necessitate intervention. The authors documented the incidence of raised intracranial pressure in children with mild features and/or parental ...
Park Jin Suk - - 2012
This study was designed to assess the effects of pneumoperitoneal pressure (PP) and positional changes on the respiratory mechanics during laparoscopy assisted colectomy. Peak inspiratory pressure, plateau pressure, lung compliance, and airway resistance were recorded in PP of 10 mmHg and 15 mmHg, with the position change in 5 steps: ...
Porta A A Department of Biomedical Sciences for Health, Galeazzi Orthopedic Institute, University of Milan, Milan, Italy. - - 2012
It is unclear whether the complexity of the variability of the systolic arterial pressure (SAP) provides complementary information to that of the heart period (HP). The complexity of HP and SAP variabilities was assessed from short beat-to-beat recordings (i.e., 256 cardiac beats). The evaluation was made during a pharmacological protocol ...
Somkuti Judit - - 2012
Contrary to the classical view, according to which all proteins adopt a specific folded conformation necessary for their function, intrinsically unstructured proteins (IUPs) display random-coil-like conformation under physiological conditions. We compared the structured and unstructured domains from titin, a giant protein responsible for striated-muscle elasticity. A 171-residue-long fragment (polyE) of ...
Sheth Kevin N - - 2012
OBJECTIVE: Detecting and treating elevated intracranial pressure (ICP) is a cornerstone of management in patients with severe traumatic brain injury. The aim of this study was to determine the association between area under the curve measurement of elevated ICP and clinical outcome. METHODS: Single center observational study using prospectively collected ...
Al-Jehani Hosam M - - 2012
Management of intracranial hypertension is a major cornerstone of neurocritical care. Apart from traumatic brain injury, there are no clear guidelines for intracranial pressure (ICP) monitoring. The insertion of ICP monitors is an invasive procedure with inherent risks and could be contraindicated in case of severe coagulopathy. The transcranial Doppler ...
Xia Wang - - 2012
Objective To explore the effects of different liquid therapies on the intracranial pressure, brain water content, and expressions of aquaporin-4 and N-methyl-D-aspartate-1 in the brain tissue. Methods Two intervention factors including the colloids (two levels: 4% gelofusine; 6% hydroxyethyl starch and sodium chloride injection) and the crystal/gel ratios (two levels: ...
Md Sina Grape - - 2012
Persisting severe brain edema causes intracranial hypertension and is associated with poor patient outcome. The treatment of acute intracranial hypertension is complex and multimodal. The most important options for medical treatment include controlled ventilation and osmotherapy, maintenance of brain and body homeostasis, and sedation. Osmotherapy is recommended in all relevant ...
Hamilton Robert R Neural Systems and Dynamics Laboratory, Department of Neurosurgery, the David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Ave., Los Angeles, CA 90095, - - 2012
This study identifies a novel relationship between cerebrospinal fluid (CSF) stroke volume through the cerebral aqueduct and the characteristic peaks of the intracranial pulse (ICP) waveform. ICP waveform analysis has become much more advanced in recent years; however, clinical practice remains restricted to mean ICP, mainly due to the lack ...
Mathieu Antoine - - 2012
BACKGROUND:: In patients with severe brain injury, endotracheal suctioning (ETS) can increase intracranial pressure (ICP) and reduce cerebral perfusion pressure (CPP). The aim of this prospective, blinded clinical trial was to assess the effectiveness of aerosolized lidocaine to prevent increase of ICP induced by ETS in mechanically ventilated head-injured patients. ...
Goldstein David S DS Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892-1620, USA. - - 2012
A cardinal manifestation of chronic autonomic failure is neurogenic orthostatic hypotension (OH), which often is associated with supine hypertension, posing a therapeutic dilemma. We report here success in a first step toward development of a "prosthetic baroreceptor system" to maintain blood pressure during orthostasis without worsening supine hypertension. In all ...
Brady Ken M - - 2012
The pressure reactivity index (PRx) identifies optimal cerebral perfusion pressure after traumatic brain injury. We describe a method to improve PRx precision by induced variations in arterial blood pressure (ABP) using positive end-expiratory pressure (PEEP) modulation (iPRx). Neonatal swine (n = 10) were ventilated with static PEEP and then with ...
Tang Peter - - 2012
We compare scaphoid excision and 4-bone arthrodesis (FBA) with proximal row carpectomy (PRC) in terms of contact pressure, area, and location. Six cadaveric forearms underwent simulated FBA with K-wires. We measured pressures in the radiocarpal joint with Fuji contact film after we applied a 200-N load via the wrist tendons ...
Piacsek Andrew A - - 2012
A possible method for noninvasively monitoring changes in intracranial pressure is to measure changes in skull resonance frequencies. Recent measurements of the vibrational response of a spherical aluminum shell clearly demonstrate that resonance frequencies shift higher as the internal pressure is increased [Piacsek et al, J. Acous. Soc. Am, 131, ...
Dal Cengio Leonardi Alessandra - - 2012
Since an increasing number of returning military personnel are presenting with neurological manifestations of traumatic brain injury (TBI), there has been a great focus on the effects resulting from blast exposure. It is paramount to resolve the physical mechanism by which the critical stress is being inflicted on brain tissue ...
Nazirizadeh Yousef - - 2012
We propose and demonstrate a visual, all-optical pressure-measuring device composed of a flexible membrane dilating toward a photonic crystal slab. Due to its transparency and capability to be miniaturized, it may be integrated on the inner side of an artificial lens and directly measure the eye's intraocular pressure. Using crossed ...
Volpe Massimo M Department of Clinical and Molecular Science, Division of Cardiology, Faculty of Medicine, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy. - - 2012
Angiotensin II receptor blockers (ARBs) inhibit the renin-angiotensin system. As a result, these agents provide beneficial effects in terms of cardiovascular (CV) and renal protection, independent of their blood pressure-lowering effects. Telmisartan and valsartan are the most intensively studied ARBs for the effects on CV outcomes. Randomized clinical trials assessing ...
Gutbrod Andreas - - 2012
OBJECTIVE: To evaluate the effect of 15° external rotational humeral osteotomy (ERHO) on canine elbow joint contact mechanics. STUDY DESIGN: Ex vivo biomechanical study. SAMPLE POPULATION: Unpaired cadaveric canine thoracic limbs (n = 8) METHODS: Digital pressure sensors placed in a subchondral osteotomy distal to the elbow joint were used ...
Ode Gabriella E - - 2012
BACKGROUND:Radial transection of the peripheral fibers of the meniscus could render it nonfunctional; however, the biomechanical consequences of a complete lateral meniscal radial tear and repair in human specimens have not been elucidated. HYPOTHESIS:A complete radial tear will exhibit knee contact mechanics approaching those of total meniscectomy. Repair of complete ...
Matityahu A M - - 2012
Open reduction and internal fixation of a distal radius fracture can leave a volar plate in close proximity or touching the tendons of the wrist. This cadaveric study examines the how volar plate position changes contact pressure and force against the flexor pollicis longus (FPL) tendon in multiple wrist extension ...
Schimpf Melissa M - - 2012
Increased intracranial pressure (ICP) is a challenging complication to treat within a critical care setting. It is imperative that clinicians use a stepwise approach in developing a diagnosis, as to be comprehensive and decrease morbidity and mortality related to increased ICP. This article provides an algorithm that can be used ...
Posthuma Leo - - 2012
Species sensitivity distributions (SSDs) quantify fractions of species potentially affected in contaminated environmental compartments using test species sensitivity data. The present study quantitatively describes associations between predicted and observed ecological impacts of contaminant mixtures, based on monitoring data of benthic macroinvertebrates. Local mixture toxic pressures (multi-substance potentially affected fraction of ...
Martinelli N - - 2012
Previous studies reported the effect of flatfoot deformity on tibiotalar joint contact characteristics. The lateral shift of the load which occurred in flatfeet may be responsible for degenerative changes in the ankle joint. The purpose was to assess the pattern of joint contact stress of the tibiotalar joint in intact, ...
Lin Tony - - 2012
BACKGROUND: The active compression test has been described to detect superior labrum anterior and posterior (SLAP) lesions. Some have speculated that contact between the lesser tuberosity and the superior glenoid in the testing position causes a positive test. This study evaluated the location of peak glenohumeral contact pressures during a ...
Guo Jing - - 2012
We report a finding of a pressure-induced quantum critical transition in K_{0.8}Fe_{x}Se_{2} (x=1.7 and 1.78) superconductors through in situ high-pressure electrical transport and x-ray diffraction measurements in diamond anvil cells. Transitions from metallic Fermi liquid behavior to non-Fermi liquid behavior and from antiferromagnetism to paramagnetism are found in the pressure range ...
Terry B - - 2012
The intraluminal pressures and traction forces associated with the Migrating Motor Complex are well understood; however, the contact forces directly exerted by the bowel wall on a solid, or near solid, bolus have not previously been measured. Quantifying contact forces is an important component to understanding the net force experienced ...
Elguizaoui Sameh - - 2012
PURPOSE: To determine whether proud synthetic and proud osteochondral plugs conform to native surrounding cartilage after cyclical loading and if there are differences in height and contact pressure after loading. METHODS: Sixteen bovine knees were used. Each received one osteochondral plug and one of two types of synthetic plugs (Smith ...
Choi Cheol - - 2012
Multi-component oil-based nanofluids were prepared by dispersing two different carbons and silver nanoparticles in lubricating oil; then, their tribological properties were investigated using a four-ball tribotester and FZG machine. Each nanofluid demonstrated excellent wear resistance or extreme pressure (EP) properties, but not both properties simultaneously. Therefore, a new concept of ...
Davies Kate E - - 2012
Postoperative or pressure alopecia (PA) is an infrequently reported group of scarring and non-scarring alopecias. It has been reported after immobilization of the head during surgery and following prolonged stays on intensive care units, and may be analogous to a healed pressure ulcer. This review presents a summary of cases ...
Cheema Tahseen - - 2012
PURPOSE: Radial subluxation and cartilage thinning have been associated with initiation and accelerated development of osteoarthritis of the trapeziometacarpal joint. Few investigators have reported on the benefits of opening wedge trapezial osteotomy for altering the contact mechanics of the trapeziometacarpal joint as a possible deterrent to the initiation or progression ...
Xu Feng - - 2012
We present a fiber-optic extrinsic Fabry-Perot interferometer pressure sensor based on a nanothick silver diaphragm. The sensing diaphragm, with a thickness measured in a few hundreds of nanometers, is fabricated by the electroless plating method, which provides a simple fabrication process involving a high-quality diaphragm at a low cost. The ...
Højlund Jakob - - 2012
Background. The prone position is applied to facilitate surgery of the back and to improve oxygenation in the respirator-treated patient. In particular, with positive pressure ventilation the prone position reduces venous return to the heart and in turn cardiac output (CO) with consequences for cerebral blood flow. We tested in ...
Liu Hai - - 2012
This study was conducted to characterize the intracranial pressure response to non-penetrating ballistic impact using a "scalp-skull-brain" pig physical head model and live pigs. Forty-eight ballistic tests targeting the physical head model and anesthetized pigs protected by aramid plates were conducted with standard 9 mm bullets at low (279-297 m/s), ...
Eide Per Kristian PK Department of Neurosurgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway. - - 2012
We recently reported that in an experimental setting the zero pressure level of solid intracranial pressure (ICP) sensors can be altered by electrostatics discharges. Changes in the zero pressure level would alter the ICP level (mean ICP); whether spontaneous changes in mean ICP happen in clinical settings is not known. ...
Kim Mi Ok MO Australian School of Advanced Medicine, Macquarie University, Sydney, Australia. - - 2012
The pulsatile energy transmission between arterial blood pressure (BP) and intracranial pressure (ICP) is affected by cerebrospinal fluid (CSF) and brain tissue. Studies in dogs have shown that the transfer function (TF) between BP and ICP shows damping of pulsatile energy around heart rate frequency (1-3Hz) with notch filter characteristics, ...
Muehlsteff Jens J Philips Research Europe, Eindhoven, The Netherlands. - - 2012
Blood pressure regulation failures cause neurally mediated syncope often resulting in a fall. A warning device might help to make patients aware of an impending critical event or even trigger the patient to perform countermeasures such as lying down or isometric exercises. We previously demonstrated that the Pulse Arrival Time ...
Lima Wildberg Alencar - - 2011
Positive intrathoracic pressure may cause hemodynamic changes, which can be transmitted to the cranial compartment, changing intracranial pressure and cerebral perfusion pressure. This can be increased when high positive end-expiratory pressure values are used. To measure the impact of different positive end-expiratory pressure levels on intracranial pressure, cerebral perfusion pressure ...
Lange Matthias - - 2011
Different isoforms of nitric oxide (NO) synthase are critically involved in the development of pulmonary failure secondary to acute lung injury. Here we tested the hypothesis that simultaneous blockade of inducible and neuronal NO synthase effectively prevents the pulmonary lesions in an ovine model of acute respiratory distress syndrome induced ...
Ng Tien M H TM University of Southern California School of Pharmacy, Los Angeles, CA 90033, - - 2012
Acute renal insufficiency is associated with poorer outcomes in heart failure. Data regarding the renal effects of vasodilatory therapy in acute heart failure are inconclusive. Nesiritide and nitroglycerin are associated with differing effects on the incidence of acute renal injury and glomerular filtration rate changes. A retrospective cohort study of ...
Patel Jayesh - - 2011
Spinal deformity, a common problem in children with myelodysplasia, is associated with alterations in pulmonary function and sitting balance. Sitting imbalance causes areas of high pressure in patients already at high risk for developing pressure ulcers due to insensate skin. We asked: Does spinal deformity affect pulmonary function tests in ...
Dorfman Jon D - - 2011
BACKGROUND: Intracranial hypertension is a crucial modifiable risk factor for poor outcome after traumatic brain injury (TBI). Limited evidence suggests that decompressive laparotomy may be an effective treatment for refractory ICH in patients who have elevated intra-abdominal pressure. METHODS: Case report. RESULTS: We present a multi-trauma patient who sustained severe ...
Zafar Syed Nabeel - - 2011
BACKGROUND:: Recent research explores the relationship between vital signs on arrival to the emergency department and early outcomes. This work has not included traumatic brain injury (TBI). We aimed to evaluate the relationship of the initial emergency department systolic blood pressure (EDSBP) with outcome. METHODS:: By using the National Trauma ...
Yokobori Shoji - - 2011
BACKGROUND:: The aim of this study was to evaluate the time course of recovery from cerebral vulnerability, using microdialysis (MD) technique and cerebral vascular autoregulation measurement, to clarify the appropriate timing of subsequent major surgical procedures, and to minimize the possibility of secondary brain injury in patients with severe traumatic ...
Shahsavari S - - 2011
Myogenic autoregulation of cerebral blood ow is one of the mechanisms affecting cerebral hemodynamics. Short or long-lasting changes in intracranial pressure are believed to reveal the responses of the cerebral system to myogenic stimuli. Through the incorporation of a theoretical model into the experimental measurements of cerebrovascular distensibility and compliance ...
Fedorowski Artur - - 2011
Orthostatic hypotension (OH) is associated with increased total mortality but contribution of specific death causes has not been thoroughly explored. In this prospective study, authors followed up 32,068 individuals without baseline history of cancer or cardiovascular disease (69% men; mean age, 46 years; range, 26-61 years) over a period of ...
Carrera Emmanuel E Academic Neurosurgery Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom. - - 2011
The benefit of induced hyperventilation for intracranial pressure (ICP) control after severe traumatic brain injury (TBI) is controversial. In this study, we investigated the impact of early and sustained hyperventilation on compliances of the cerebral arteries and of the cerebrospinal (CSF) compartment during mild hyperventilation in severe TBI patients. We ...
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