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Ribeiro Fernando F School of Health Sciences, University of Aveiro, Aveiro, Portugal; Research Centre in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal. Electronic address: - - 2014
The study examined the effects of treadmill walking with load carriage on derived measures of central pressure and augmentation index in young healthy subjects. Fourteen male subjects (age 31.0 ± 1.0 years) volunteered in this study. Subjects walked 10 minutes on a treadmill at a speed of 5 km/h carrying ...
Kandail Harkamaljot H Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, - - 2014
Treatment options for abdominal aortic aneurysm (AAA) include highly invasive open surgical repair or minimally invasive endovascular aneurysm repair (EVAR). Despite being minimally invasive, some patients are not suitable for EVAR due to hostile AAA morphology. Fenestrated-EVAR (F-EVAR) was introduced to address these limitations of standard EVAR, where AAA is ...
Tan Long Bin LB Department of Mechanical Engineering, National University of Singapore, - - 2014
Head injuries due to complex blasts are not well examined due to limited published articles on the subject. Previous studies have analyzed head injuries due to impact from a single planar blast wave. Complex or concomitant blasts refer to impacts usually caused by more than a single blast source, whereby ...
Childs Charmaine C Centre for Health and Social Care Research, Sheffield Hallam University, Montgomery House , 32 Collegiate Crescent , Sheffield S10 2BP - - 2014
Abstract The objective was to investigate sensor measurement uncertainty for intracerebral probes inserted during neurosurgery and remaining in situ during neurocritical care. This describes a prospective observational study of two sensor types and including performance of the complete sensor-bedside monitoring and readout system. Sensors from 16 patients with severe traumatic ...
Iwai Kosuke K Department of Mechanical Engineering, University of California, Berkeley, USA. - - 2014
Point-of-care (POC) and disposable biomedical applications demand low-power microfluidic systems with pumping components that provide controlled pressure sources. Unfortunately, external pumps have hindered the implementation of such microfluidic systems due to limitations associated with portability and power requirements. Here, we propose and demonstrate a 'finger-powered' integrated pumping system as a ...
Gao Ji J *Laboratory of Central Neuropeptides in the Regulation of Body Fluid Homeostasis and Cardiovascular Functions, CIRB, Collège de France, INSERM U1050, Paris, F-75231, - - 2014
Hypertension affects one-third of the adult population and is a growing problem due to the increasing incidence of obesity and diabetes. Brain RAS (renin-angiotensin system) hyperactivity has been implicated in the development and maintenance of hypertension in several types of experimental and genetic hypertension animal models. We have identified in the ...
Hay Meredith M Department of Physiology, University of Arizona, 1501 N Campbell Rd Bldg 201, Rm 4103, Tucson, AZ, 85724, USA, - - 2014
The role of the brain in hypertension between the sexes is known to be important especially with regards to the effects of circulating sex hormones. A number of different brain regions important for regulation of sympathetic outflow and blood pressure express estrogen receptors (ERα and ERβ). Estradiol, acting predominantly via ...
Khalifé Maya M Imagerie par Résonance Magnétique Médicale et Multi-Modalités (IR4M), Université Paris-Sud - CNRS, UMR 8081, Orsay, France. Electronic address: - - 2014
Aortic blood pressure is a strong indicator to cardiovascular diseases and morbidity. Clinically, pressure measurements are done by inserting a catheter in the aorta. However, imaging techniques have been used to avoid the invasive procedure of catheterization. In this paper, we combined MRI measurements to a one-dimensional model in order ...
Xu Gang-Zhu GZ From the *Department of Neurosurgery, First Affiliated Hospital, Medical College of Xi'an Jiaotong University; and †Department of Neurosurgery, Affiliated Hospital of Xi'an Medical College, Xi'an, - - 2014
This study was performed to investigate the effect of early pressure dressing on the prevention of postoperative subdural effusion secondary to decompressive craniectomy (DC) in patients with severe traumatic brain injury (STBI). Patients with STBI who had undergone DC for refractory increased intracranial pressure between January 2008 and December 2011 ...
Srivastava Divya D Theoretical Sciences Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru - 560064, - - 2014
First principles searches are carried out for the existence of an asymptotic scaling law for the zero temperature phonon dispersion relation of several elemental crystalline solids in the high pressure regime. The solids studied are Cu, Ni, Pd, Au, Al, and Ir in the face-centered-cubic (fcc) geometry and Fe, Re, ...
Koskinen Lars-Owe D LO Division of Pharmacology and Clinical Neuroscience, Department of Neurosurgery, Umeå University, 901 85, Umeå, Sweden, - - 2014
This prospective consecutive double-blinded randomized study investigated the effect of prostacyclin on pressure reactivity (PR) in severe traumatic brain injured patients. Other aims were to describe PR over time and its relation to outcome. Blunt head trauma patients, Glasgow coma scale ≤8, age 15-70 years were included and randomized to prostacyclin ...
Eide Per Kristian - - 2014
In order to characterize the intracranial pressure-volume reserve capacity, the correlation coefficient (R) between the ICP wave amplitude (A) and the mean ICP level (P), the RAP index, has been used to improve the diagnostic value of ICP monitoring. Baseline pressure errors (BPEs), caused by spontaneous shifts or drifts in ...
Chesnut Randall M RM Departments of Neurological Surgery and Orthopaedics and Sports Medicine, Harborview Medical Center, School of Medicine, and School of Global Health, University of Washington, Seattle, - - 2014
Current controversies in the literature suggest that a reassessment of the current management of severe traumatic brain injury (sTBI) is necessary. This article presents a conceptual framework toward individualizing sTBI treatment with respect to targeting thresholds and strategies on the basis of known physiologic processes and available monitors. Intracranial pressure ...
Lazaridis Christos C Division of Neurocritical Care, Department of Neurology, Baylor College of Medicine, 6501 Fannin Street, MS: NB 320, Houston, TX, 77030, USA, - - 2014
Prevention and detection of secondary brain insults via multimodality neuromonitoring is a major goal in patients with severe traumatic brain injury (TBI). Explore the underlying pathophysiology and clinical outcome correlates as it pertains to combined monitoring of ≥2 from the following variables: partial brain tissue oxygen tension (PbtO2), pressure reactivity ...
Roth Christian C Department of Neurology, Klinikum Kassel, Mönchebergstraße 41-43, 34125, Kassel, Germany, - - 2014
The objective of our trial was to obtain more comprehensive data on the risks and benefits of kinetic therapy in intensive care patients with intracerebral pathology. Standardized data of prone positioning in our NeuroIntensive Care Unit were collected from 2007 onward. A post hoc analysis of all available data was ...
Colton Katharine K From the Shock Trauma Anesthesia Research Organized Research Center (K.C., S.Y., P.F.H., H.H.C., B.B., T.M.S., D.M.S.), University of Maryland School of Medicine; and R Adams Cowley Shock Trauma Center (K.C., S.Y., P.F.H., H.H.C., B.B., T.M.S., D.M.S.), Baltimore, Maryland; and Duke University School of Medicine (K.C.), Durham, North - - 2014
The accepted treatment of increased intracranial pressure (ICP) in patients experiencing severe traumatic brain injury is multimodal and algorithmic, obscuring individual effects of treatment. Using continuous vital signs monitoring, we sought to measure treatment effect and ascertain the accuracy of manual data recording. Patients older than 17 years, admitted and ...
Panikkath Ragesh R Departments of Internal Medicine (Panikkath, Lado-Abeal) and Anesthesiology (Welker, Johnston), Texas Tech University Health Sciences Center, Lubbock, - - 2014
Intracranial hypertension and intracranial hypotension are on the opposite end of the intracranial pressure spectra. It is extremely uncommon for both to cause headache in the same patient within a span of several days. This report describes a young man with intracranial hypertension who developed a severe excruciating headache due ...
Sun Qing - - 2014
Mechanical ventilation with positive end-expiratory pressure (PEEP) has been advocated as an essential life support for critical patients. However, its side effect, which is demonstrated by an elevation of intracranial pressure (ICP) under normobaric (NBO2) conditions, is potentially detrimental to patients. Hyperbaric oxygen (HBO2) therapy, on the other hand, is ...
Kundra Sandeep S Department of Anesthesia, Dayanand Medical College and Hospital, Ludhiana, Punjab, - - 2014
Aneurysmal subarachnoid hemorrhage is associated with high mortality. Understanding of the underlying pathophysiology is important as early intervention can improve outcome. Increasing age, altered sensorium and poor Hunt and Hess grade are independent predictors of adverse outcome. Early operative interventions imposes an onus on anesthesiologists to provide brain relaxation. Coiling ...
Bibi Shahida S Department of Colorectal Surgery, University of Illinois at Chicago, Chicago, IL, - - 2014
The Enseal (Ethicon Endo-Surgery, Blue Ash, Ohio) tissue-sealing device has proven efficacy for ligation of vessels <7 mm in diameter, even with significant supraphysiologic bursting pressures. We aimed to evaluate the safety of Enseal in porcine vessels >7 mm. The lumbar aortas of pigs that were euthanized for unrelated procedures ...
Hassanpour Seyed Esmail SE Department of Plastic and Reconstructive Surgery, Shahid Beheshti University of Medical Sciences, Tehran, - - 2014
The nasal septal deviation (NSD) is one of the major causes of nasal obstruction. This condition increases upper airway resistance. In This study we evaluated the mean pulmonary artery pressure (MPAP) in patients with markedly deviated septum. Sixty two patients with NSD (Age range: 26-45 years, 34 men and 28 ...
Takimoto Yoshiyuki Y Department of Stress Sciences and Psychosomatic Medicine, Graduate School of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8655, - - 2014
Autonomic dysfunction of the cardiovascular system in anorexia nervosa (AN) was reported not only in the rest position, but also in the standing position in some previous studies, which might contribute to cardiac complications such as lethal arrhythmia. However, there has not been sufficient literature in this issue. Therefore, we ...
Jian M M Department of Anaesthesiology, Beijing Tiantan Hospital, Capital Medical University, No. 6 Tiantan Xili, Beijing 100050, - - 2014
Post-craniotomy intracranial haematoma is one of the most serious complications after neurosurgery. We examined whether post-craniotomy intracranial haematoma requiring surgery is associated with the non-steroidal anti-inflammatory drugs flurbiprofen, hypertension, or hydroxyethyl starch (HES). A case-control study was conducted among 42 359 patients who underwent elective craniotomy procedures at Beijing Tiantan ...
Dias Celeste C University Hospital Sao Joao, Neurocritical Care Unit, Intensive Care Department, Porto, Portugal ; - - 2014
Emerging evidence suggests that hypertonic saline (HTS) is efficient in decreasing intracranial pressure (ICP). However there is no consensus about its interaction with brain hemodynamics and oxygenation. In this study we investigated brain response to HTS bolus with multimodal monitoring after severe Traumatic Brain Injury (TBI). We included 18 consecutive ...
Zhang Shuijun S From the Department of Hepatobiliary and Pancreatic Surgery and the Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, - - 2014
Experimental animal models of brain death that mimic human conditions may be useful for investigating novel strategies that increase quality and quantity of organs for transplant. Brain death was induced by increasing intracranial pressure by inflating an intracranial placed balloon catheter. Brain death was confirmed by flatline electroencephalogram, physical signs ...
Zeiler Frederick A FA Section of Neurosurgery, Dept of Surgery, University of Manitoba, Winnipeg, Canada; Section of Neurocritical Care, Montreal Neurological Institute, McGill, Montreal, Canada. Electronic address: - - 2014
The purpose of the study was to perform a systematic review of the literature on the use of ketamine in nontraumatic neurological illness and its effects on intracranial pressure (ICP). Articles from MEDLINE, BIOSIS, EMBASE, Global Health, HealthStar, Scopus, Cochrane Library, the International Clinical Trials Registry Platform (inception to January ...
Eide Per Kristian PK Department of Neurosurgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway; Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address: - - 2014
Antisecretory factor (AF) and derivates thereof counteract brain edema and inflammation, and normalize ICP dynamics. The aim of the present study was to assess whether AF normalized the abnormal ICP waves, indicative of impaired intracranial compliance, seen in patients with idiopathic normal pressure hydrocephalus (iNPH) and idiopathic intracranial hypertension (IIH). ...
Corry Jesse J JJ Department of Neurology, Marshfield Clinic, 1000 N. Oak Ave., Marshfield, WI, 54449-5777, USA, - - 2014
The use of hypothermia for treatment of intracranial hypertension is controversial, despite no other medical therapy demonstrating consistent improvements in morbidity or mortality. Much of this may be the result of negative results from randomized controlled trials. However, the patients selected for these trials may have obscured the results in ...
Wilson Mark H MH 1 The Brain Injury Centre-St Mary's Hospital , Imperial College, London, United Kingdom - - 2014
Abstract Wilson, Mark H., Alex Wright, and Christopher H.E. Imray. Intracranial pressure at altitude. High Alt Med Biol. 15:123-132, 2014.- Rapid ascent to high altitude can result in high altitude headache, acute mountain sickness, and less commonly, high altitude cerebral or pulmonary edema. The exact mechanisms by which these clinical ...
Lewis Philip M PM Department of Neurosurgery, Alfred Hospital, 1st Floor, Old Baker Building, Commercial Road, Melbourne, VIC, 3003, Australia, - - 2014
In the healthy brain, small oscillations in intracranial pressure (ICP) occur synchronously with those in cerebral blood volume (CBV), cerebrovascular resistance, and consequently cerebral blood flow velocity (CBFV). Previous work has shown that the usual synchrony between ICP and CBFV is lost during intracranial hypertension. Moreover, a continuously computed measure ...
Kliper Yael Y Baruch Padeh Medical Center, Poria, Affiliated to the Faculty of Medicine, Bar-Ilan University, Ramat-Gan, - - 2014
Introduction: The aim of this study was to assess the effect of mild pressure applied on the abdominal wall by the ultrasound transducer on fetal cephalic indices. Material and Methods: We examined by ultrasound 60 fetuses of healthy women, at 20-24 weeks of pregnancy, during routine prenatal evaluation. For every ...
Bershad Eric M EM 1Baylor College of Medicine, Department of Neurology, Houston, TX, USA 2Smith College, Department of Engineering, Northampton, MA, USA 3Amherst College, Department of Mathematics and Statistics, Amherst, MA, - - 2014
There is an important need to develop a non-invasive method for assessing intracranial pressure. We report a novel approach for monitoring intracranial pressure using cochlear derived distortion product otoacoustic emissions, which are affected by intracranial pressure. We hypothesized that changes of intracranial pressure may be reflected by altered DPOAE responses ...
Wang Xin X Department of Anesthesiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 Yanchang zhong Road, Shanghai, 200072, - - 2014
Ketamine is traditionally avoided in sedation management of patients with risk of intracranial hypertension. However, results from many clinical trials contradict this concern. We critically analyzed the published data of the effects of ketamine on intracranial pressure (ICP) and other cerebral hemodynamics to determine whether ketamine was safe for patients ...
Stocchetti Nino N Department of Physiopathology and Transplant, Milan University, Neuro ICU, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, - - 2014
Intracranial pressure (ICP) monitoring has been for decades a cornerstone of traumatic brain injury (TBI) management. Nevertheless, in recent years, its usefulness has been questioned in several reports. A group of neurosurgeons and neurointensivists met to openly discuss, and provide consensus on, practical applications of ICP in severe adult TBI. ...
Santamaria Ruben R Department of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721-0041, - - 2014
The evolution of the vibrational spectra of the isoelectronic hydrogen clusters H26, H24He, and H24Li(+) is determined with pressure. We establish the vibrational modes with collective character common to the clusters, identify their individual vibrational fingerprints and discuss frequency shifts in the giga-Pascal pressure region. The results are of interest ...
Picetti Edoardo E I Servizio Anestesia e Rianimazione, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci 14, 43100, Parma, Italy, - - 2014
Fever occurs frequently in acute brain injury patients, and its occurrence is associated with poorer outcomes. Paracetamol, an antipyretic frequently employed in patients with cerebral damage, may cause hypotension. We evaluated the cerebral and hemodynamic effects of intravenous (IV) paracetamol for the control of fever in Neuro-Intensive Care Unit (NICU) ...
Laffer Cheryl L CL The Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address: - - 2014
An rs3890011 variant of CYP4A11, which is in linkage disequilibrium with the loss-of-function variant rs1126742, is associated with hypertension in humans. In mice, Cyp4a deficiency results in salt-sensitive hypertension through activation of ENaC. We tested the hypothesis that the rs3890011 variant is associated with blood pressure response to drugs acting ...
Andrade Chittaranjan C From the *Department of Psychopharmacology, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India and †University of Copenhagen, Psychiatric Center Copenhagen, - - 2014
Preclinical and clinical evidence show that electroconvulsive therapy (ECT)-induced intraictal surge in blood pressure may result in a small, transient breach in the blood-brain barrier, leading to mild cerebral edema and a possible leach of noxious substances from blood into brain tissues. These changes may impair neuronal functioning and contribute ...
Lawley Justin S JS Extremes Research Group, School of Sport, Health and Exercise Sciences, Bangor University, Gwynedd; Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, - - 2014
Objective Identify if normobaric hypoxia causes elevated brain volume and intracranial pressure in individuals with symptoms consistent with acute mountain sickness (AMS). Methods Thirteen males (26(sd 6) years) were exposed to normobaric hypoxia (12% O2 ) and normoxia (21% O2 ). After 2 and 10 hours, AMS symptoms were assessed ...
Depreitere Bart B Neurosurgery - - 2014
Object In severe traumatic brain injury, a universal target for cerebral perfusion pressure (CPP) has been abandoned. Attempts to identify a dynamic CPP target based on the patient's cerebrovascular autoregulatory capacity have been promising so far. Bedside monitoring of pressure autoregulatory capacity has become possible by a number of methods, ...
Nakadate Hiromichi - - 2014
Intracranial pressure changes during head impact cause brain injuries such as vasogenic edema and cerebral contusion. However, the influence of impulsive pressure on endothelial function has not yet been fully studied in vitro. In this study, we developed a pressure loading device that produced positive and negative pressures by modifying ...
Sahin Yıldız Banu B Department of Internal Medicine, Dr. Lütfi Kırdar Kartal Educational and Research Hospital; İstanbul-Turkey. - - 2014
The effects of acute hemodialysis session on pulse wave velocity are conflicting. The aim of the current study was to assess the acute effects of ultrafiltration on the aortic mechanical properties using carotid-femoral (aortic) pulse wave velocity and pulse propagation time. A total of 26 (12 women, 14 men) consecutive ...
Enok Sanne S Aarhus University, - - 2014
Interspecific allometric analyses indicate that mean arterial blood pressure (MAP) increases with body mass of snakes and mammals. In snakes, MAP increases in proportion to the increased distance between the heart and the head, when the heart-head vertical distance is expressed a ρgh, and the rise in MAP is associated ...
Nikulin Vadim V VV Neurophysics Group, Department of Neurology, Campus Benjamin Franklin, Charité, University Medicine, Hindenburgdamm 30, 12203 Berlin, Germany; Bernstein Center for Computational Neuroscience, Philippstraße 12, 10115 Berlin, Germany. Electronic address: - - 2014
Previous studies demonstrated the presence of Monochromatic Ultra-Slow Oscillations (MUSO) in human EEG. In the present study we explored the biological origin of MUSO by simultaneous recordings of EEG, Near-Infrared Spectroscopy (NIRS), arterial blood pressure, respiration and laser Doppler flowmetry. We used a head-up tilt test in order to check ...
Zeiler F A FA Section of Neurosurgery, Department of Surgery, University of Manitoba, Winnipeg, Canada, - - 2014
Our goal was to perform a systematic review of the literature on the use of tromethamine (THAM) and its effects on intracranial pressure (ICP) in patients with neurological illness. All articles from MEDLINE, BIOSIS, EMBASE, Global Health, HealthStar, Scopus, Cochrane Library, the International Clinical Trials Registry Platform (inception to February ...
Zhu Feng F Bioengineering Center, Wayne State University, Detroit, MI, - - 2014
Traumatic brain injury due to primary blast loading has become a signature injury in recent military conflicts. Efforts have been made to study the stress wave propagation in the head. However, the relationship of incident pressure, reflected pressure and intracranial pressure is still not clear, and the experimental findings reported ...
Andresen Morten M Clinic of Neurosurgery, Copenhagen University Hospital, Copenhagen, - - 2014
Object Current published normal values for intracranial pressure (ICP) are extrapolated from lumbar CSF pressure measurements and ICP measurements in patients treated for CSF pressure disorders. There is an emerging agreement that true normal ICP values are needed for diagnostic and therapeutic purposes. This study documents normal ICP in humans. ...
Otvos Balint B Cleveland Clinic Lerner College of Medicine; - - 2014
In 1919, it was observed that intravascular osmolar shifts could collapse the thecal sac and diminish the ability to withdraw CSF from the lumbar cistern. This led to the notion that hyperosmolar compounds could ameliorate brain swelling. Since then, various therapeutic interventions have been used for the reduction of intracranial ...
Kumar Ramesh R Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2014
In children with acute CNS infection, management of raised intracranial pressure improves mortality and neuromorbidity. We compared cerebral perfusion pressure-targeted approach with the conventional intracranial pressure-targeted approach to treat raised intracranial pressure in these children. Prospective open-label randomized controlled trial. PICU in a tertiary care academic institute. Hundred ten children ...
Zweifel Christian C Academic Neurosurgical Unit, University of Cambridge Department of Clinical Neurosciences, Cambridge, United Kingdom; Department of Neurosurgery, University Hospital of Basel, Basel, Switzerland. Electronic address: - - 2014
Integration of various brain signals can be used to determine cerebral autoregulation in neurocritical care patients to guide clinical management and to predict outcome. In this review, we will discuss current methodology of multimodal brain monitoring focusing on secondary 'reactivity indices' derived from various brain signals which are based on ...
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