Search Results
Results 401 - 450 of 1698
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Akinci Seda B - - 2002
OBJECTIVE: To describe the clinical, hemodynamic, and echocardiographic findings of cardiac tamponade in a patient with portopulmonary hypertension shortly after orthotropic liver transplantation. DESIGN: Case report. SETTING: Surgical intensive care unit of a university teaching hospital. PATIENT: One patient with portopulmonary hypertension deteriorated progressively after orthotropic liver transplantation and developed ...
Summers R L - - 2002
Noninvasive ventilation using noninvasive bilevel positive airway pressure (Bi-PAP) has been shown to be an effective means of improving oxygenation and respiratory status in patients with obstructive pulmonary disease (COPD) and acute congestive heart failure (CHF). However, it is uncertain what effects this positive airway pressure has on the haemodynamic ...
Wright Christine E - - 2002
BACKGROUND: The structural changes in hypertension include narrowing of the lumen of the large resistance vessels and an increase in their wall thickness : lumen ratio. Their haemodynamic role has been controversial. OBJECTIVE: To examine resting haemodynamics and the responses to graded drug-induced changes in tone in renal cellophane-wrap (wrap) ...
Sakka Samir G SG Department of Anesthesiology and Intensive Care Medicine, Friedrich-Schiller-University of Jena, Jena, Germany. - - 2002
We prospectively studied the agreement between transpulmonary aortic fiberoptic-based and pulse dye densitometry (PDD) measurements of cardiac output and circulatory blood volumes. Prospective clinical study. Operative ICU of a university hospital. Sixteen critically ill, deeply sedated patients receiving mechanical ventilation with ARDS (n = 8), sepsis/septic shock (n = 6), ...
Alkins Stephan A - - 2002
Recent guidelines reinforce the need for a standardized technique during inhalational bronchoprovocation challenge testing. We investigated the effects of nebulizer model and dosimeter driving pressure on nebulizer output using a nebulized saline model. Four nebulizers (Hudson 1720, Salter 8900, Baxter Airlife, and DeVilbiss 644) were evaluated at two driving pressures ...
Adachi Wataru - - 2002
BACKGROUND: Although the complication rate of endoscopy is low, EGD may induce cardiac stress. The aim of this study was to quantify cardiac stress during EGD. METHODS: Heart rate, blood pressure, cardiac output, and peripheral oxygen saturation were measured during endoscopy without sedation in 7 volunteers. Cardiac output was measured ...
Vasquez Alejandro - - 2002
The pericardium influences cardiac performance indirectly, but pathologic conditions may have profound effects on cardiac function. In recent years, several imaging modalities have been useful, both clinically and in understanding the pathophysiology of pericardial diseases. Rising pericardial pressures progressively reduce the average transmural pressure of the right and subsequently left ...
GÅ©nal Ali Ihsan - - 2002
BACKGROUND: In some haemodialysis patients, blood pressure increases during the dialysis session despite ultrafiltration (UF). METHODS: We investigated six such patients who were not responsive to hypotensive drugs. Their echocardiograms were obtained prior to and during the dialysis session. RESULTS: After the mean 2520 +/- 1698 (4.5 +/- 2.3% of ...
Frank Steven M - - 2002
Postoperative hypothermia increases the incidence of ischaemic cardiac events in patients at risk, but the underlying mechanism is unclear. One possibility is increased cardiac work related to the sympathoneural or adrenomedullary hormonal responses. In awake human volunteers, the present study assessed the effects of mild core hypothermia on these responses, ...
Gregg M Elizabeth - - 2002
A quantitative, theory-driven model of hemodynamics was developed, relating reactivity in blood pressure to orthogonal dimensions of "hemodynamic profile" and "compensation deficit," which were derived from the (multiplicative) interaction of cardiac output and total peripheral resistance. A Finapres 2300e was used to estimate blood pressure, cardiac output, and total peripheral ...
Bengtsson Jan - - 2002
OBJECTIVE: Simple, preferably noninvasive measurements of cardiac output are useful in pediatric patients receiving inotropic support. Oxygen saturation in pulmonary artery (Svo(2)) gives information about oxygen delivery and demand. Many inotropic drugs influence oxygen consumption. When effects on Svo(2) are studied, after a change in inotropic drug dosage, a change ...
Tachibana Kazuya - - 2002
BACKGROUND: Recently, a new device has been developed to measure cardiac output noninvasively using partial carbon dioxide (CO(2)) rebreathing. Because this technique uses CO(2) rebreathing, the authors suspected that ventilatory settings, such as tidal volume and ventilatory mode, would affect its accuracy: they conducted this study to investigate which parameters ...
Mulder A L - - 2001
Fetal responses to acute hypoxemia include bradycardia, increase in blood pressure, and peripheral vasoconstriction. Peripheral vasoconstriction contributes to the redistribution of the cardiac output away from ancillary vascular beds toward myocardial, cerebral, and adrenal circulations. We investigated the effect of alpha-adrenergic receptor blockade on this fetal response. Fluorescent microspheres were ...
Schou M - - 2001
Previous results from our laboratory indicate that the heart is distended by the left lateral position (LAT) compared to horizontal supine (SUP). We therefore tested the hypothesis that cardiac output is increased by LAT and that mean arterial pressure is maintained unchanged or even decreased through peripheral vasodilatation induced by ...
Lamont L A - - 2001
OBJECTIVE: To evaluate the cardiovascular effects of the alpha2-adrenergic receptor agonist medetomidine hydrochloride in clinically normal cats. ANIMALS: 7 clinically normal cats. PROCEDURE: Cats were anesthetized with isoflurane, and thermodilution catheters were placed for measurement of central venous, pulmonary, and pulmonary capillary wedge pressures and for determination of cardiac output. ...
Ruiz-Feria C A - - 2001
Previous studies have suggested cardiac taurine is released into the plasma in response to hypoxemia (low blood oxygen levels) during the pathogenesis of pulmonary hypertension syndrome (PHS, ascites). In the present study, broilers reared under cool temperature conditions (16 C) were provided tap water (control group), tap water supplemented with ...
Kennedy R R - - 2001
Cardiac output is one of the major determinants of the rate of uptake, and therefore the end-expired concentration (F(E')) of volatile anaesthetic agents. The purpose of this theoretical study was to explore the effect of cardiac output changes on F(E') for a range of volatile anaesthetics. A multicompartment model of ...
Perry S F - - 2001
The aim of the present study was to evaluate the effects of endothelin-l-elicited cardiovascular events on respiratory gas transfer in the freshwater rainbow trout (Oncorhynchus mykiss) and the marine dogfish (Squalus acanthias). In both species, endothelin-1 (666 pmol kg(-1)) caused a rapid (within 4 min) reduction (ca. 30-50 mmHg) in ...
Gruhn N - - 2001
BACKGROUND AND PURPOSE: Arterial blood pressure and cardiac output are often reduced in patients with chronic heart failure (CHF). Counterregulatory mechanisms with increased neurohormonal activation and changes in the distribution of cardiac output are assumed to secure vital organ perfusion. However, clinical examination of patients with CHF frequently reveals neurological ...
Phoon C K - - 2001
Knowledge of early developmental circulatory physiology has lagged behind advances in molecular cardiology. Cardiovascular physiology changes during embryonic development in a highly complex and carefully orchestrated manner, tightly correlated with structural development. Circulatory changes in early development include increasing heart rate, preload, and cardiac output; decreasing peripheral resistance; and increasing ...
Harper S L - - 2001
Adult crayfish have a neurogenic heart which is modulated via inputs from the central nervous system and neurohormones, which act on the cardiac ganglion or directly on the myocardium. This study investigates the ontogeny of cardiac regulation by exploring the temporal sequence of cardiac sensitivity to injections of cardioactive neurohormones ...
Wiesenack C - - 2001
OBJECTIVE: To analyze the clinical value of a new device (PiCCO) for cardiac output measurement and volume preload parameter assessment, based on transpulmonary thermodilution technique, as an alternative to the pulmonary artery thermodilution technique and assessment of pressure preload parameters derived from the pulmonary artery catheter. DESIGN: Prospective, controlled, clinical ...
Razavi R S - - 2001
BACKGROUND: Alagille's syndrome is a rare condition that is characterized by paucity of interlobular bile ducts and peripheral pulmonary artery stenosis. Liver transplantation in the setting of peripheral pulmonary stenosis and right ventricular hypertension seems to be associated with a higher mortality, which raises the concern that these patients are ...
Kasznicki J - - 2001
The aim of the present study was to establish the effect of intravenous administration of indomethacin (10 mg/kg), potent inhibitor of prostaglandin synthesis, on hemodynamic parametrs after intravenous administration of propranolol (0.3 mg/kg) and enalaprilat (0.5 mg/kg) in rabbits. The following parameters were estimated: mean arterial blood pressure, heart rate, ...
Gersbach P A - - 2001
BACKGROUND: The effects of thoracolumbal spinal cord stimulation (SCS) are confined to restricted microcirculatory areas. This limitation is generally attributed to a predominantly segmental mode of action on the autonomic nervous system. The goal of this study was to determine whether SCS applied close to supraspinal autonomic centers would induce ...
Cariga P - - 2001
Oral water ingestion increases blood pressure in normal elderly subjects and in patients suffering from autonomic failure, but the time course of the haemodynamic changes is not known. We therefore studied 14 subjects with documented sympathetic denervation due to pure autonomic failure, with continuous haemodynamic recordings obtained before and after ...
Buhre W - - 2001
BACKGROUND: Measurements of intrathoracic blood volume (ITBV) provide volumetric information about cardiac preload and are used to investigate the cause of alterations in cardiac output (CO). On the other hand, CO is required to calculate ITBV. Thus, concerns have been raised with respect to a mathematical coupling of data. The ...
Cotter G - - 2001
This study investigated the effect of tezosentan (an intravenous endothelin-1 receptor antagonist) on vascular resistance and cardiac function and determined the dose response in patients with stable congestive heart failure (CHF) due to left ventricular systolic dysfunction. In a double-blind fashion, tezosentan or placebo were administered in ascending doses (5, ...
Arora R C - - 2001
We sought to determine the behavior of intrinsic cardiac neurons in human subjects undergoing cardiac surgery and to correlate their activity with hemodynamics status. A lead II electrocardiogram, pulmonary artery pressure, and systemic arterial pressure were recorded along with extracellular activity generated by right atrial neurons in 10 patients undergoing ...
Sitbon P - - 2001
OBJECTIVE: This study was conducted with the aim of testing the effects of a reduction in tidal volume (V(T)) on gastric mucosal perfusion using laser-Doppler flowmetry in patients with acute respiratory distress syndrome (ARDS). DESIGN: It was designed as a prospective study. PATIENTS: Seventeen patients with ARDS were enrolled in ...
Nelson L D - - 2001
OBJECTIVE: To evaluate the clinical significance of mathematical coupling on the correlation between cardiac output and right ventricular end-diastolic volume (RVEDV) through measurement of cardiac output by two independent techniques. DESIGN: Prospective, observational study. SETTING: Surgical intensive care unit in a level 1 trauma center. PATIENTS: Twenty-eight critically ill surgical ...
García-Delgado M - - 2001
OBJECTIVE: To determine the influence of dopamine- and dobutamine-induced increases in cardiac output on the extravascular lung water in an experimental model of pulmonary edema. DESIGN: Animal experimental study. SETTING: Animal experimental laboratory of a tertiary hospital. SUBJECTS: Mixed-race pigs (n = 20) weighing 28-32 kg. INTERVENTIONS: After the animals ...
Parsonage W A - - 2001
OBJECTIVE: To characterise the central and regional haemodynamic effects of insulin in patients with chronic heart failure. DESIGN: Single blind, placebo controlled study. SETTING: University teaching hospital. PATIENTS: Ten patients with stable chronic heart failure. INTERVENTIONS: Hyperinsulinaemic euglycaemic clamp and non-invasive haemodynamic measurements. MAIN OUTCOME MEASURES: Change in resting heart ...
Mariano-Goulart D - - 2001
The aim of this preliminary study was to evaluate the accuracy of left and right ventricular output computed from a semi-automatic processing of tomographic radionuclide ventriculography data (TRVG) in comparison with the conventional thermodilution method. Twenty patients with various heart diseases were prospectively included in the study. Thermodilution and TRVG ...
Clark D I - - 2001
In a prospective, controlled study, we measured the effect on cardiac output of the introduction of methylmethacrylate during hemiarthroplasty for displaced fractures of the femoral neck. We treated 20 elderly patients who were similar in age, height, weight and preoperative left ventricular function with either cemented or uncemented hemiarthroplasty. Using ...
Rivers R J - - 2001
BACKGROUND: The authors developed an indicator dilution technique for small animals to repeatedly determine cardiac output and blood volume without cardiac instrumentation or blood sampling. METHODS: Observations were made in the hamster (N = 32, 70 mg/kg pentobarbital) cremaster using in vivo fluorescence videomicroscopy. Fluorescein isothiocyanate-conjugated bovine serum albumin (10 ...
Paganel F - - 2001
The effects of digitalis on the baroreflexes in human chronic heart failure have been well studied. Similarly, since it has been recently shown that chemoregulation remains generally effective during cardiac failure, the goal of this study was to evaluate the effects of a chronic administration of digoxin on the chemoreflexes. ...
Ordoñez A - - 2001
INTRODUCTION: Paraaortic or external aortic counterpulsation is been investigated as a definitive ventricular assistance in cases of terminal congestive heart failure and when heart transplantation is counterindicated. Our aims is to assess the haemodynamic effects of an descending aortomyoplasty in a biological model of congestive heart failure. MATERIALS AND METHODS: ...
Ripplinger C M - - 2001
Aside from the traditional diagnostic tools used to assess cardiac performance, such as blood pressure and cardiac output, cardiac source parameters can also be used as an indication of overall cardiac health. The cardiac source parameters under investigation are myocardial visco-elastic properties. The objective of this study is to model ...
Donovan F M FM - - 2001
Cardiac output is measured by the thermal dilution method which uses a quadruple lumen catheter, with a thermistor on the tip, through the right atrium, right ventricle and into the pulmonary artery. Cold saline is injected into the right atrium and the resulting pulmonary artery temperature profile is integrated. The ...
Grant C - - 2001
OBJECTIVE: To determine if a commonly used analgesic dose of xylazine has detrimental cardiovascular or haemodynamic effects in sheep. DESIGN: A physiological study following intramuscular administration of xylazine. PROCEDURE: Xylazine (50 micrograms/kg) was injected intramuscularly into six healthy Merino ewes. For 60 min heart rate, mean arterial blood pressure and ...
Olsson K - - 2001
Echocardiography and Doppler measurements were performed to investigate changes in heart dimensions and function during pregnancy, lactation and the non-pregnant, non-lactating (dry) period in dairy goats. Eight Swedish domestic goats (Capra hircus) were studied with two-dimensional (2DE), M-mode and continuous wave Doppler measurements. Cardiac dimensions did not differ between periods. ...
Kirch W - - 2001
BACKGROUND: For the past two decades, it has generally been accepted ('Blaustein hypothesis') that cardiac glycosides such as ouabain and digoxin increase the sodium and calcium content of smooth muscle cells, so inducing arterial vasoconstriction and a rise in blood pressure. Recent data from an experimental study we carried out ...
Lester S J - - 2000
BACKGROUND: The psychoactive stimulant 3, 4-methylenedioxymethamphetamine (MDMA), also known as "ecstasy," is widely used in nonmedical settings. Little is known about its cardiovascular effects. OBJECTIVE: To evaluate the acute cardiovascular effects of MDMA by using transthoracic two-dimensional and Doppler echocardiography. DESIGN: Four-session, ascending-dose, double-blind, placebo-controlled trial. SETTING: Urban hospital. PATIENTS: ...
Krueger U - - 2000
BACKGROUND: A prospective, randomised study was undertaken to investigate the effect of intravenous infusion of either iloprost, the stable prostacyclin (PGI2) analogue, or alprostadil (prostaglandin E1) on peripheral resistance (PR) during femoro-distal reconstruction. METHODS: A prospective randomised study was performed with 35 patients. The PR Measurement of peripheral resistance involved ...
King M L - - 2000
BACKGROUND: Controversy surrounds the use of resistance exercise in patients with heart failure because of concerns that increases in rate-pressure product and systemic vascular resistance might lead to increased afterload and decreased cardiac output. METHODS: Following pharmacologic left ventricular unloading therapy using a pulmonary artery catheter, 34 patients with advanced ...
Scardo J A - - 2000
OBJECTIVE: We sought to evaluate the capacity of a new thoracic electric bioimpedance system to estimate cardiac output in patients with preeclampsia. STUDY DESIGN: We performed a prospective comparison of thoracic electric bioimpedance and echocardiographic M-mode volumetric estimates of cardiac output (in liters per minute) in preeclampsia. Subjects with preeclampsia ...
Augoustides J - - 2000
Surgery on the central blood pump, the heart, is performed either to prevent homeostatic compromise (ie, coronary artery disease potentially causing myocardial infarction and heart failure) or to treat actual homeostatic imbalance (ie, valvular disease causing heart failure). The cardiovascular homeostatic state is what we generally define as hemodynamics. The ...
Wiktorowska-Owczarek A - - 2000
Some of anesthetic drugs cause cardiac arrhythmia, myocardial depression, blood pressure as well as hepatic and renal blood flow decrease. The aim of the following research study was the evaluation of midazolam effect on hemodynamic parameters in propranolol-treated rabbits. The following parameters: cardiac output and stroke volume, peripheral blood resistance, ...
Kirkebø A - - 2000
The haemodynamic responses to arachidonic acid (AA) have been investigated in seven groups of anaesthetized rats. Sodium arachidonate was infused intravenously for 4 or 20 min, and arterial blood pressure was recorded continuously. Cardiac output and organ blood flow were measured by microspheres. Infusion of arachidonate caused first a fast ...
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