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Zhao Wei W Thayer School of Engineering, Dartmouth College, 14 Engineering Drive, Hanover, NH, 03755, - - 2014
Brain pressure responses resulting from translational head impact are typically related to focal injuries at the coup and contrecoup sites. Despite significant efforts characterizing brain pressure responses using experimental and modeling approaches, a thorough investigation of the key controlling parameters appears lacking. In this study, we identified three parameters specific ...
Bradley W G WG Jr From the Department of Radiology, University of California, San Diego, San Diego, California. - - 2014
CSF normally flows back and forth through the aqueduct during the cardiac cycle. During systole, the brain and intracranial vasculature expand and compress the lateral and third ventricles, forcing CSF craniocaudad. During diastole, they contract and flow through the aqueduct reverses. Hyperdynamic CSF flow through the aqueduct is seen when ...
- - 2014
THIS META-ANALYSIS compares randomised controlled trials of two approaches to the management of raised intracranial pressure (ICP) in traumatic brain injury: the use of mannitol versus that of hypertonic sodium.
Imam Ayesha A Bloomfield, United States ; - - 2014
We have previously shown that early treatment with Fresh Frozen Plasma (FFP) is neuroprotective in a swine model of hemorrhagic shock (HS) and Traumatic Brain Injury (TBI). However, it remains unknown whether this strategy would be beneficial in a more clinical poly-trauma model. To answer this, Yorkshire swine (42-50 kg) ...
Belkoniene Mhedi M From the *Cardiovascular Research, Department of Surgery, University Hospital - Centre Hospitalier Universitaire Vaudois; and †Laboratory for Movement Analysis, Swiss Federal Institute of Technology, Lausanne, - - 2014
Originally, the Smartcanula principle (collapsed insertion and expansion in situ) was developed for venous drainage by gravity. However, in minimally invasive surgery, augmentation with either constrained force vortex pumps or vacuum is often used. The current study was set up to assess whether smaller diameters of self-expanding venous cannulas are ...
Aasvang E K EK Section of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, - - 2014
Deep pain complaints are more frequent than cutaneous in post-surgical patients, and a prevalent finding in quantitative sensory testing studies. However, the preferred assessment method - pressure algometry - is indirect and tissue unspecific, hindering advances in treatment and preventive strategies. Thus, there is a need for development of methods ...
Miyahara Masaaki M Institute of Mineralogy, Petrology and Economic Geology, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan;Department of Earth and Planetary Systems Science, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan; - - 2014
Howardite-eucrite-diogenite meteorites (HEDs) probably originated from the asteroid 4 Vesta. We investigated one eucrite, Béréba, to clarify a dynamic event that occurred on 4 Vesta using a shock-induced high-pressure polymorph. We discovered high-pressure polymorphs of silica, coesite, and stishovite originating from quartz and/or cristobalite in and around the shock-melt veins ...
Polónia Jorge J Unidade de Hipertensão Arterial e Risco Cardiovascular, Hospital Pedro Hispano, Matosinhos, Portugal; Faculdade de Medicina, Universidade do Porto, Porto, Portugal. Electronic address: - - 2014
We investigated viscoelastic properties of the arterial wall in women with previous preeclampsia (PE) compared to those with normal pregnancy (NP). In a cross-sectional study 45 women with previous PE and 55 with NP were included, matched for age (PE 38±6 vs. NP 38±5 years, NS) and body mass index: ...
Esfahani D D Department of Neurosurgery, University of Illinois at Chicago, Chicago, IL, - - 2014
Endovascular stenting is an effective treatment available for patients with clinically significant cerebral venous sinus stenosis. Traditionally, stenting success has been determined by intravascular pressure measurements; new imaging modalities, however, show great potential in documenting improved flow and providing noninvasive monitoring of venous patency after treatment. Quantitative MRA (NOVA, VasSol ...
Tziomalos Konstantinos - - 2014
In addition to the modification of the lipid profile, most lipid-lowering agents appear to modulate other atherogenic pathways. We summarize the effects of lipid-lowering agents on inflammation, hemostasis and blood pressure. We also discuss the potential contribution of these actions on cardiovascular disease prevention. Most lipid-lowering agents appear to exert ...
Nusbaum Derek - - 2014
Objectives: Recent studies suggest that elevated intracranial pressure (ICP), created by hydrocephalus, can alter the lower limit of cerebrovascular autoregulation (LLA). Our objective in the present study was to determine if ICP elevation from cerebral venous outflow obstruction would result in comparable alterations in the LLA. Methods: Anesthetized juvenile pigs ...
De Simone R R Headache Centre Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples "Federico II" - - - 2014
In recent years the efficacy of endovascular venous stenting in idiopathic intracranial hypertension (IIH) treatment has been consistently reported, strongly suggesting that sinus stenosis should be viewed as a causative factor rather than a secondary phenomenon. We propose that in subjects carrying one or more collapsible segments of large cerebral ...
Kurstjens Rlm R Department of Vascular Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands CARIM, School for Cardiovascular Diseases, Maastricht, The Netherlands - - 2014
Iliofemoral venous obstruction, caused by post-thrombotic disease, can be treated by percutaneous angioplasty and additional stenting with good results. However, no hemodynamic parameter determining the need for treatment has been defined. This article describes the preliminary results of a study investigating the pressure changes occurring in post-thrombotic deep venous obstruction. ...
Partsch Hugo H Emeritus Professor of Dermatology, Medical University of Vienna, Vienna, Austria - - 2014
Compression therapy is the most important basic treatment modality in venous leg ulcers. The review focusses on the materials which are used: 1. Compression bandages, 2. Compression stockings, 3. Self-adjustable Velcro-devices, 4. Compression pumps, 5. Hybrid devices. Compression bandages, usually applied by trained staff, provide a wide spectrum of materials ...
Mosti Giovanni G Angiology Department, Clinica MD Barbantini, Lucca - Italy - - 2014
arterial involvement may coexist in about 15-30 of venous ulcers. In this case compression therapy maybe applied, only by expert caregivers, with a reduced pressure which must not overcome the arterial pressure at ankle and foot level. It remains to assess if such a reduced pressure may be effective also ...
Zarchi Kian K Department of Dermatology, Roskilde Hospital, Health Science Faculty, University of Copenhagen, Roskilde, - - 2014
IMPORTANCE Despite the documented effect of compression therapy in clinical studies and its widespread prescription, treatment of venous leg ulcers is often prolonged and recurrence rates high. Data on provided compression therapy are limited. OBJECTIVE To assess whether home care nurses achieve adequate subbandage pressure when treating patients with venous ...
Licks Francielli F Universidade Federal do Rio Grande do Sul, Programa de Pós Graduação em Ciências Biológicas: Fisiologia. - - 2014
Background. Portal hypertension is a clinical syndrome associated with the development of a hyperdynamic circulation and gastroesophageal varices. Aim. To evaluate the antioxidant effect of N-acetylcysteine on portal hypertensive rats. Material and methods. Portal hypertension was induced by partial portal vein ligation (PPVL). Oxidative damage in the stomach was measured ...
Jonckers Tinneke - - 2014
Aim: To study the effect of in-line filtering on in-line pressure measurement in a simulated infusion system.Methods: The experimental setup consisted of a syringe pump, syringe, intravenous (IV) line, and extension line. For aqueous fluids, a 0.2-μm infusion filter was used, and for lipid emulsions, a 1.2-μm filter. Infusion speed ...
Han Sun Sook SS Department of Anesthesiology and Pain Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, - - 2014
The respiratory cycle alters the size of the right internal jugular vein (RIJV). We assessed the changes in RIJV size during the respiratory cycle in patients under positive pressure ventilation. Moreover, we examined the effects of positive-end expiratory pressure (PEEP) and the Trendelenburg position on respiratory fluctuations. A prospective study ...
Gutiérrez-González Raquel R Department of Neurosurgery, Fundación Jiménez Díaz (IIS-FJD), Avda Reyes Católicos 2, 28040, Madrid, Spain, - - 2014
One of the most life-threatening complications after the obliteration of intracranial arteriovenous malformations is the development of oedema and/or multifocal haemorrhage. Two main theories have been postulated so far in order to explain this situation. On one hand, "normal perfusion pressure breakthrough phenomenon" is based on the loss of cerebral ...
Li Fan Dong FD General Hospital of Jinan Military District, Jinan, - - 2014
IMPORTANCE Long-term patency of human saphenous veins (HSVs) used as autologous conduits for coronary artery bypass grafting (CABG) procedures remains limited because of vein graft failure (VGF). Vein graft failure has been reported to be as high as 45% at 12 to 18 months after surgery and leads to additional ...
Ichimura Mika M Department of Nursing, School of Health Science and Social Welfare, Kibi International University, Takahashi, Okayama, Japan; Graduate School of Health and Welfare Science, Okayama Prefectural University, Soja, Okayama, - - 2014
This study aimed to investigate relations between ease of venous palpation and various venous factors, and to elucidate characteristics of hardly palpable veins. Healthy adult volunteers (n = 110) were enrolled. The ease of venous palpation was scored from 0: impalpable to 3: well palpable. Venous factors, namely venous depth, elevation, area ...
Chen Chih-Wei - - 2014
Objectives: Multiple methods of selective brain cooling have been used to prevent cerebral ischemia secondary to trauma and pathological or iatrogenic cerebral blood flow restriction. In this study, we tested the efficacy of hypothermic retrograde jugular vein flush (HRJVF) in eliciting selective brain hypothermia in a porcine model. Methods: Twelve ...
De Blasi Roberto Alberto RA Department of Medical & Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, "Sapienza" via di Grottarossa 1035, 00189, Rome, - - 2014
Quantitative near infrared spectroscopy (NIRS) measurements for microvascular blood volume (MBV) partitioning inside microvessels are of current physiologic and clinical interest. In this study in healthy subjects we sought new bedside NIRS variables for non invasively measuring unstressed blood volume (Vu) and intravascular pressure (Pi) changes. Fifteen healthy subjects underwent ...
Genc Arzu A School of Physical Therapy and Rehabilitation (Dr Genc) and Department of Anesthesiology and Reanimation, School of Medicine, Dokuz Eylül University, Izmir, Turkey (Drs Koca and - - 2014
Passive limb exercises (PLEs) are used widely in the management of unconscious patients and an early start is recommended. The aim of this study was to determine the effects of PLEs on hemodynamic and respiratory parameters in mechanically ventilated critically ill patients receiving low-dose vasopressor/inotropic support. The charts of 120 ...
F Cutting Keith K Visiting Professor, Buckinghamshire New University, - - 2014
Graduated external compression lies at the heart of effective management of venous leg ulceration by reducing oedema and supporting venous return to the heart.
Uhl J-F JF URDIA research unit, EA 4465, Paris Descartes University, - - 2014
Using standing magnetic resonance imaging (MRI), we recently showed that medical compression, providing an interface pressure (IP) of 22 mmHg, significantly compressed the deep veins of the leg but not, paradoxically, superficial varicose veins. To provide an explanation for this compression paradox by studying the correlation between the IP exerted by ...
Lattimer Christopher R CR Josef Pflug Vascular Laboratory, Ealing and Northwick Park Hospitals and Imperial College, London, - - 2014
Reactive hyperaemia following thigh compression increases arterial inflow and venous outflow. The net effect can be measured by changes in calf volume quantified using air-plethysmography. The objective was to investigate the effect of thigh compression on venous return. The right legs of 19 consecutive volunteers (14 male), median age 31 ...
Pfisterer Larissa L Department of Physiology and Pathophysiology, University of Heidelberg, - - 2014
The development of varicose veins or chronic venous insufficiency is preceded by and associated with the pathophysiological remodelling of the venous wall. Recent work suggests that an increase in venous filling pressure is sufficient to promote varicose remodelling of veins by augmenting wall stress and activating venous endothelial and smooth ...
Young Brian C BC Department of Emergency and Critical Care, The Animal Medical Center, New York, NY, - - 2014
To evaluate traditional and global perfusion parameters in clinical canine shock patients, and to evaluate for occult hypoperfusion as evidenced by low central venous oxygen saturation or high plasma lactate concentrations in clinical patients resuscitated to traditional endpoints. Clinical observational trial designed with a 1-year data entry period and patient ...
Hamajima Yuki Y a Department of Life Science , Rikkyo University , Tokyo , - - 2014
The chimeric 3-isopropylmalate dehydrogenase enzymes were constructed from the deep-sea piezophilic Shewanella benthica and the shallow water Shewanella oneidensis genes. The properties of the enzymatic activities under pressure conditions indicated that the central region, which contained the active center and the dimer forming domains, was shown to be the most ...
Mosti G G Clinica MD Barbantini, Via del Calcio n.2, Lucca, Italy. Electronic address: - - 2014
Previous studies have shown that so-called progressive elastic compression stockings (PECS) with a negative pressure gradient have a more pronounced effect on venous pump function than conventional, graduated stockings. The aim of this study was to investigate the effect of higher graduated and non-graduated pressures on the venous calf pump ...
Kule Amy A Department of Emergency Medicine, William Beaumont Hospital, Royal Oak, - - 2014
Venous access can occasionally be difficult to obtain secondary to near-complete compressibility of peripheral veins in some patients. This study utilizes ultrasound to assess vein compressibility with different tourniquet techniques commonly available in the emergency department. After approval by the Institutional Review Board, a prospective single-center study was conducted assessing ...
Rajendram Rajkumar - - 2014
In critical illness, septic shock is a contributing factor in nearly half of all cases of acute kidney injury (AKI). Traditional approaches to prevention of organ dysfunction in early sepsis have focused on prevention of hypoperfusion by optimisation of systemic haemodynamics, primarily by fluid resuscitation. Fluid administration to a target ...
Sinagra E E Internal Medicine Unit, A.O. Ospedali Riuniti Villa Sofia Cervello - P.O. Vincenzo Cervello, Palermo, Italy; Endoscopy and Gastroenterology Unit, Fondazione Istituto San Raffaele Giglio, Cefalù, - - 2014
Propranolol is recommended for prophylaxis of variceal bleeding in cirrhosis. Carvedilol is a nonselective beta-blocker with a mild anti-alfa-1-adrenergic activity. Several studies have compared carvedilol and propranolol, yielding inconsistent results. To perform a systematic review and meta-analysis of the randomised clinical trials comparing carvedilol with propranolol for hepatic vein pressure ...
Pagonas Nikolaos N Arteriogenesis Research Group, Center for Cardiovascular Research (CCR) & Department of Cardiology, CVK, Charité - Universitätsmedizin Berlin, Berlin, - - 2014
Aims: This study sought to evaluate the reproducibility of the index of microcirculatory resistance (IMR) in a follow-up model and the role of epicardial artery stenosis and central venous pressure (Pv) on IMR. Methods and results: Twenty-two patients with stable coronary artery disease underwent coronary catheterisation at baseline and after ...
Doğrul Ahmet Bülent AB Şişli Memorial Hospital, Solid Organ Transplantation Unit, Okmeydanı, Istanbul, - - 2014
Clamping of the portal vein during a recipient hepatectomy during the anhepatic phase causes venous stagnation and hemodynamic instability. To prevent this, a temporary portocaval shunt is placed at some centers. This case report shows the patent umbilical vein of a patient undergoing a recipient hepatectomy, leading to a 20% ...
Wakai Nobuhiko N Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, - - 2014
The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C. acrolepis, carp, and rabbit/human/chicken actins using molecular dynamics simulations at 0.1 and 60 MPa. The amino acid sequences of actins are highly conserved across a variety ...
Haussen Diogo C DC Department of Neurosurgery, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida, - - 2014
Periprocedural intracranial hemorrhage secondary to intranidal flow redirection may develop after arteriovenous malformation (AVM) embolization. We hypothesized that continuous draining vein pressure monitoring may identify clinically relevant hemodynamic changes during devascularization. Our goal was to characterize the draining vein pressures in a swine rete mirabile AVM model during embolization with ...
Li Liang L Cardio-Vascular Research, Department of Surgery and Anesthesiology, CHUV, Lausanne, - - 2014
During open heart surgery, so-called atrial chatter, a phenomenon due to right atria and/or caval collapse, is frequently observed. Collapse of the cava axis during cardiopulmonary bypass (CPB) limits venous drainage and may result downstream in reduced pump flow on (lack of volume) and upstream in increased after-load (stagnation), which ...
Longchamp Alban A Department of Thoracic and Vascular Surgery, University Hospital, Laboratory of Experimental Medicine, Bugnon 21, 1011 Lausanne, - - 2014
The saphenous vein is the conduit of choice in bypass graft procedures. Haemodynamic factors play a major role in the development of intimal hyperplasia (IH), and subsequent bypass failure. To evaluate the potential protective effect of external reinforcement on such a failure, we developed an ex vivo model for the perfusion ...
Moeslein Fred M FM Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 South Greene St, Baltimore, MD, 21201, USA, - - 2014
A new melphalan hemoperfusion filter (GEN 2) was evaluated in a simulated-use porcine model of percutaneous hepatic perfusion (PHP). The current study evaluated melphalan filtration efficiency, the transfilter pressure gradient, and the removal of specific blood products. A porcine PHP procedure using the GEN 2 filter was performed under Good ...
Larimer P P Department of Neurology, University of California San Francisco, San Francisco, CA, - - 2014
Chronic paroxysmal intracranial hypertension leading to syncope is a phenomenon not reported previously in patients with refractory cerebral venous sinus thrombosis. We report a case of paroxysmal intracranial hypertension leading to syncopal episodes in a patient with idiopathic autoimmune hemolytic anemia and venous sinus thrombosis. This case demonstrates that intermittent ...
Song Young Y Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, - - 2014
We present a case of a patient exhibiting isolated elevation of the central venous pressure with minimal hemodynamic deterioration in an immediate postoperative period after Bentall operation requiring re-exploration. Isolated elevation of the central venous pressure usually alerts physicians of a volume overload or right ventricular dysfunction. However, even in ...
Huang Weibin W Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, - - 2014
Duffy antigen / receptor for chemokines (DARC) possesses high affinity for several chemokine subgroups of CC and CXC. Although DARC has been shown to play a role in many inflammatory diseases, its effect on chronic venous disease (CVD) remains unidentified. We explored whether the expression of DARC in skin tissue ...
Alia-Klein Nelly N Department of Psychiatry, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America; Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of - - 2014
Media portraying violence is part of daily exposures. The extent to which violent media exposure impacts brain and behavior has been debated. Yet there is not enough experimental data to inform this debate. We hypothesize that reaction to violent media is critically dependent on personality/trait differences between viewers, where those ...
Hinojosa-Laborde Carmen C 1University of Texas Health Science Center at San - - 2013
Lower body negative pressure (LBNP), a model of hemorrhage (Hem), shifts blood to the legs and elicits central hypovolemia. This study compared responses to LBNP and actual Hem in sedated baboons. Arterial pressure, pulse pressure (PP), central venous pressure (CVP), heart rate, stroke volume (SV), and +dP/dt were measured. Hem ...
Ribitsch Werner W Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, - - 2013
Venous needle dislodgement (VND) is a potentially fatal complication during hemodialysis (HD) treatment and the venous pressure monitor is the most widely used device for its detection. VND can only be detected by the venous sensor if the resulting pressure drop exceeds the difference between the actual venous pressure and ...
Miller Jimmy D - - 2013
Most acute subdural hematomas (ASDHs) develop after rupture of a bridging vein or veins. The anatomy of the bridging vein predisposes to its tearing within the border cell layer of the dura mater. Thus, the subdural hematoma actually forms within the dura. The hematoma grows by continued bleeding into the ...
Kneller Wendy W Department of Psychology, University of Winchester, Hampshire, UK. - - 2013
Prior research has indicated that inert gas narcosis (IGN) causes decrements in free recall memory performance and that these result from disruption of either encoding or self-guided search in the retrieval process. In a recent study we provided evidence, using a Levels of Processing approach, for the hypothesis that IGN ...
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