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Ichimura Mika M Department of Nursing, School of Health Science and Social Welfare, Kibi International University, Takahashi, Okayama, Japan; Graduate School of Health and Welfare Science, Okayama Prefectural University, Soja, Okayama, - - 2014
This study aimed to investigate relations between ease of venous palpation and various venous factors, and to elucidate characteristics of hardly palpable veins. Healthy adult volunteers (n = 110) were enrolled. The ease of venous palpation was scored from 0: impalpable to 3: well palpable. Venous factors, namely venous depth, elevation, area ...
Chen Chih-Wei - - 2014
Objectives: Multiple methods of selective brain cooling have been used to prevent cerebral ischemia secondary to trauma and pathological or iatrogenic cerebral blood flow restriction. In this study, we tested the efficacy of hypothermic retrograde jugular vein flush (HRJVF) in eliciting selective brain hypothermia in a porcine model. Methods: Twelve ...
De Blasi Roberto Alberto RA Department of Medical & Surgical Sciences and Translational Medicine, Faculty of Medicine and Psychology, University of Rome, "Sapienza" via di Grottarossa 1035, 00189, Rome, - - 2014
Quantitative near infrared spectroscopy (NIRS) measurements for microvascular blood volume (MBV) partitioning inside microvessels are of current physiologic and clinical interest. In this study in healthy subjects we sought new bedside NIRS variables for non invasively measuring unstressed blood volume (Vu) and intravascular pressure (Pi) changes. Fifteen healthy subjects underwent ...
Genc Arzu A School of Physical Therapy and Rehabilitation (Dr Genc) and Department of Anesthesiology and Reanimation, School of Medicine, Dokuz Eylül University, Izmir, Turkey (Drs Koca and - - 2014
Passive limb exercises (PLEs) are used widely in the management of unconscious patients and an early start is recommended. The aim of this study was to determine the effects of PLEs on hemodynamic and respiratory parameters in mechanically ventilated critically ill patients receiving low-dose vasopressor/inotropic support. The charts of 120 ...
F Cutting Keith K Visiting Professor, Buckinghamshire New University, - - 2014
Graduated external compression lies at the heart of effective management of venous leg ulceration by reducing oedema and supporting venous return to the heart.
Uhl J-F JF URDIA research unit, EA 4465, Paris Descartes University, - - 2014
Using standing magnetic resonance imaging (MRI), we recently showed that medical compression, providing an interface pressure (IP) of 22 mmHg, significantly compressed the deep veins of the leg but not, paradoxically, superficial varicose veins. To provide an explanation for this compression paradox by studying the correlation between the IP exerted by ...
Lattimer Christopher R CR Josef Pflug Vascular Laboratory, Ealing and Northwick Park Hospitals and Imperial College, London, - - 2014
Reactive hyperaemia following thigh compression increases arterial inflow and venous outflow. The net effect can be measured by changes in calf volume quantified using air-plethysmography. The objective was to investigate the effect of thigh compression on venous return. The right legs of 19 consecutive volunteers (14 male), median age 31 ...
Pfisterer Larissa L Department of Physiology and Pathophysiology, University of Heidelberg, - - 2014
The development of varicose veins or chronic venous insufficiency is preceded by and associated with the pathophysiological remodelling of the venous wall. Recent work suggests that an increase in venous filling pressure is sufficient to promote varicose remodelling of veins by augmenting wall stress and activating venous endothelial and smooth ...
Young Brian C BC Department of Emergency and Critical Care, The Animal Medical Center, New York, NY, - - 2014
To evaluate traditional and global perfusion parameters in clinical canine shock patients, and to evaluate for occult hypoperfusion as evidenced by low central venous oxygen saturation or high plasma lactate concentrations in clinical patients resuscitated to traditional endpoints. Clinical observational trial designed with a 1-year data entry period and patient ...
Mosti G G Clinica MD Barbantini, Via del Calcio n.2, Lucca, Italy. Electronic address: - - 2014
Previous studies have shown that so-called progressive elastic compression stockings (PECS) with a negative pressure gradient have a more pronounced effect on venous pump function than conventional, graduated stockings. The aim of this study was to investigate the effect of higher graduated and non-graduated pressures on the venous calf pump ...
Kule Amy A Department of Emergency Medicine, William Beaumont Hospital, Royal Oak, - - 2014
Venous access can occasionally be difficult to obtain secondary to near-complete compressibility of peripheral veins in some patients. This study utilizes ultrasound to assess vein compressibility with different tourniquet techniques commonly available in the emergency department. After approval by the Institutional Review Board, a prospective single-center study was conducted assessing ...
Rajendram Rajkumar - - 2014
In critical illness, septic shock is a contributing factor in nearly half of all cases of acute kidney injury (AKI). Traditional approaches to prevention of organ dysfunction in early sepsis have focused on prevention of hypoperfusion by optimisation of systemic haemodynamics, primarily by fluid resuscitation. Fluid administration to a target ...
Sinagra E E Internal Medicine Unit, A.O. Ospedali Riuniti Villa Sofia Cervello - P.O. Vincenzo Cervello, Palermo, Italy; Endoscopy and Gastroenterology Unit, Fondazione Istituto San Raffaele Giglio, Cefalù, - - 2014
Propranolol is recommended for prophylaxis of variceal bleeding in cirrhosis. Carvedilol is a nonselective beta-blocker with a mild anti-alfa-1-adrenergic activity. Several studies have compared carvedilol and propranolol, yielding inconsistent results. To perform a systematic review and meta-analysis of the randomised clinical trials comparing carvedilol with propranolol for hepatic vein pressure ...
Pagonas Nikolaos N Arteriogenesis Research Group, Center for Cardiovascular Research (CCR) & Department of Cardiology, CVK, Charité - Universitätsmedizin Berlin, Berlin, - - 2014
Aims: This study sought to evaluate the reproducibility of the index of microcirculatory resistance (IMR) in a follow-up model and the role of epicardial artery stenosis and central venous pressure (Pv) on IMR. Methods and results: Twenty-two patients with stable coronary artery disease underwent coronary catheterisation at baseline and after ...
Doğrul Ahmet Bülent AB Şişli Memorial Hospital, Solid Organ Transplantation Unit, Okmeydanı, Istanbul, - - 2014
Clamping of the portal vein during a recipient hepatectomy during the anhepatic phase causes venous stagnation and hemodynamic instability. To prevent this, a temporary portocaval shunt is placed at some centers. This case report shows the patent umbilical vein of a patient undergoing a recipient hepatectomy, leading to a 20% ...
Wakai Nobuhiko N Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, - - 2014
The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C. acrolepis, carp, and rabbit/human/chicken actins using molecular dynamics simulations at 0.1 and 60 MPa. The amino acid sequences of actins are highly conserved across a variety ...
Haussen Diogo C DC Department of Neurosurgery, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, Florida, - - 2014
Periprocedural intracranial hemorrhage secondary to intranidal flow redirection may develop after arteriovenous malformation (AVM) embolization. We hypothesized that continuous draining vein pressure monitoring may identify clinically relevant hemodynamic changes during devascularization. Our goal was to characterize the draining vein pressures in a swine rete mirabile AVM model during embolization with ...
Li Liang L Cardio-Vascular Research, Department of Surgery and Anesthesiology, CHUV, Lausanne, - - 2014
During open heart surgery, so-called atrial chatter, a phenomenon due to right atria and/or caval collapse, is frequently observed. Collapse of the cava axis during cardiopulmonary bypass (CPB) limits venous drainage and may result downstream in reduced pump flow on (lack of volume) and upstream in increased after-load (stagnation), which ...
Longchamp Alban A Department of Thoracic and Vascular Surgery, University Hospital, Laboratory of Experimental Medicine, Bugnon 21, 1011 Lausanne, - - 2014
The saphenous vein is the conduit of choice in bypass graft procedures. Haemodynamic factors play a major role in the development of intimal hyperplasia (IH), and subsequent bypass failure. To evaluate the potential protective effect of external reinforcement on such a failure, we developed an ex vivo model for the perfusion ...
Moeslein Fred M FM Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 South Greene St, Baltimore, MD, 21201, USA, - - 2014
A new melphalan hemoperfusion filter (GEN 2) was evaluated in a simulated-use porcine model of percutaneous hepatic perfusion (PHP). The current study evaluated melphalan filtration efficiency, the transfilter pressure gradient, and the removal of specific blood products. A porcine PHP procedure using the GEN 2 filter was performed under Good ...
Larimer P P Department of Neurology, University of California San Francisco, San Francisco, CA, - - 2014
Chronic paroxysmal intracranial hypertension leading to syncope is a phenomenon not reported previously in patients with refractory cerebral venous sinus thrombosis. We report a case of paroxysmal intracranial hypertension leading to syncopal episodes in a patient with idiopathic autoimmune hemolytic anemia and venous sinus thrombosis. This case demonstrates that intermittent ...
Huang Weibin W Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, - - 2014
Background: Duffy antigen / receptor for chemokines (DARC) possesses high affinity for several chemokine subgroups of CC and CXC. Although DARC has been shown to play a role in many inflammatory diseases, its effect on chronic venous disease (CVD) remains unidentified. We explored whether the expression of DARC in skin ...
Song Young Y Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, - - 2014
We present a case of a patient exhibiting isolated elevation of the central venous pressure with minimal hemodynamic deterioration in an immediate postoperative period after Bentall operation requiring re-exploration. Isolated elevation of the central venous pressure usually alerts physicians of a volume overload or right ventricular dysfunction. However, even in ...
Hinojosa-Laborde Carmen C 1University of Texas Health Science Center at San - - 2013
Lower body negative pressure (LBNP), a model of hemorrhage (Hem), shifts blood to the legs and elicits central hypovolemia. This study compared responses to LBNP and actual Hem in sedated baboons. Arterial pressure, pulse pressure (PP), central venous pressure (CVP), heart rate, stroke volume (SV), and +dP/dt were measured. Hem ...
Ribitsch Werner W Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, - - 2013
Venous needle dislodgement (VND) is a potentially fatal complication during hemodialysis (HD) treatment and the venous pressure monitor is the most widely used device for its detection. VND can only be detected by the venous sensor if the resulting pressure drop exceeds the difference between the actual venous pressure and ...
Miller Jimmy D - - 2013
Most acute subdural hematomas (ASDHs) develop after rupture of a bridging vein or veins. The anatomy of the bridging vein predisposes to its tearing within the border cell layer of the dura mater. Thus, the subdural hematoma actually forms within the dura. The hematoma grows by continued bleeding into the ...
Kneller Wendy W Department of Psychology, University of Winchester, Hampshire, UK. - - 2013
Prior research has indicated that inert gas narcosis (IGN) causes decrements in free recall memory performance and that these result from disruption of either encoding or self-guided search in the retrieval process. In a recent study we provided evidence, using a Levels of Processing approach, for the hypothesis that IGN ...
Legrand Matthieu - - 2013
The role of systemic hemodynamics in the pathogenesis of septic acute kidney injury (AKI) has received little attention. The purpose of this study was to investigate the association between systemic hemodynamics and new or persistent of AKI in severe sepsis. A retrospective study between 2006 and 2010 was performed in ...
Enouri Saad - - 2013
Background/Aims: The vascular regulatory function of the endothelium can be impaired by increases in transmural pressure (TMP). We tested the hypothesis that increasing TMP impairs the endothelial dilator function of rat mesenteric small veins (MSVs). Methods: In PGF2α-preconstricted MSVs, bradykinin (BK), sodium nitroprusside (SNP) and S-Nitroso-N-acetylpenicillamine (SNAP) concentration-response curves were ...
Sternberg Zohara - - 2013
This study is the first in a series investigating the relationship between autonomic nervous system dysfunction and chronic cerebrospinal venous insufficiency in multiple sclerosis patients. We screened patients for the combined presence of the narrowing of the internal jugular veins and symptoms of autonomic nervous system dysfunction (fatigue, cognitive dysfunction, ...
Epstein K L KL Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, - - 2014
Lower molecular weight and molar substitution formulations of hydroxyethyl starch (HES) solutions might maximize cardiovascular function and colloid osmotic pressure (COP) and minimize adverse effects on coagulation. To compare effects of 1 low and 1 high molecular weight and molar substitution HES solution on cardiovascular variables, COP, and hemostasis in ...
Mestre Nélia C - - 2013
The advent of industrial activities in the deep sea will inevitably expose deep-sea organisms to potentially toxic compounds. Although international regulations require environmental risk assessment prior to exploitation activities, toxicity tests remain focused on shallow-water model species. Moreover, current tests overlook potential synergies that may arise from the interaction of ...
Kondo Takayuki - - 2013
The aim was to determine the influence of the paraumbilical vein (PUV) patency and its effect on the portal hemodynamics and clinical presentations in cirrhotic patients. In this prospective study of 181 cirrhotic patients (101 males, 80 females; aged 62.6±11.8 y), the portal hemodynamics were assessed using Doppler ultrasonography. The ...
Lattimer C R - - 2013
Graduated elastic compression (GEC) stockings reduce reflux and venous volume but their performance on augmenting venous return is unproven. The aim of this study was to quantify the ability of stockings to increase venous outflow from the leg. A prospective study comparing venous emptying without compression, versus class 1 (18-21 mmHg) ...
Kutty Shelby - - 2013
Compromise of right heart function is an important feature of many forms of congenital heart disease, and right atrial (RA) pressure is clinically relevant. Inferior vena cava (IVC) diameter and inspiratory collapse are indices of RA pressure, but pediatric data are lacking. RA measurements, systemic venous diameters, and Doppler filling ...
Ajlan Abdulrazag M - - 2013
Spontaneous intracranial hypotension (SIH) is a syndrome of low pressure headache associated with low CSF pressure. The condition is generally considered benign but extreme cases of SIH can lead to changes in the level of consciousness. We describe a case in which alteration in the level of consciousness was prolonged ...
Chua Chiaco John Michael S - - 2013
Assessment of the jugular venous pressure is often inadequately performed and undervalued. Here, we review the physiologic and anatomic basis for the jugular venous pressure, including the discrepancy between right atrial and central venous pressures. We also describe the correct method of evaluating this clinical finding and review the clinical ...
Kotlinska-Hasiec Edyta - - 2013
Disturbances in venous outflow from the cerebral circulation may result in brain injury. Severe increases in brain venous pressure lead to brain ischemia and, subsequently, brain edema and intracranial hemorrhages. The purpose of this study was to determine the effect of changes in jugular venous bulb pressure (JVBP) on plasma ...
Santhanakrishnan Arvind - - 2013
The Fontan surgical procedure used for treating patients with single ventricle (SV) congenital heart disorders results in a total cavopulmonary connection (TCPC) of the vena cavae to the pulmonary arteries (PAs). Sluggish TCPC flow and elevated hepatic venous pressures are commonly observed in this altered physiology, which in turn can ...
Nusbaum Derek M - - 2013
Nontraumatic, nonhydrocephalic increases in intracranial pressure (ICP) are often difficult to diagnose and may underlie spaceflight-related visual changes. This study looked at the utility of a porcine animal model of increasing cephalic venous pressure to mimic acute changes in ICP and optic nerve sheath diameter (ONSD) from cephalic venous fluid ...
Ducrocq N - - 2013
In the current management of critically ill patients, variables such as blood pressure, urine output or central venous pressure guide resuscitative efforts. Unfortunately, global tissue hypoxia may persist leading to multiple organ failure and death. To address tissue well-being, indices such as central venous oxygen saturation (ScvO2) and Lactatemia are ...
Vinay Byrappa - - 2013
Venous air embolism (VAE) is a well recognized complication during neurosurgery. Pre-cordial doppler and trans-esophageal echocardiography are sensitive monitors for the detection of VAE. A sudden, abrupt reduction in the end-tidal carbondioxide (ETCO2) pressure with associated hypotension during neurosurgery might suggest VAE, when more sensitive monitors are not available. We ...
Simons Ap - - 2013
Aim:Without volume-buffering capacity in extracorporeal life support (ELS) systems, hypovolemia can acutely reduce support flow. This study aims at evaluating efficacy and safety of strategies for preserving stable ELS during hypovolemia.Material & METHODS: Flow and/or pressure-guided servo pump control, a reserve-driven control strategy and a volume buffer capacity (VBC) device ...
Wang David Hsiao-Chuan - - 2013
Graduated compression bandaging of the lower limbs is the primary therapy for venous leg ulcers with its efficacy believed to be predominantly dependent on the amount and the distribution of the compressive pressure applied. There has been on-going demand for an ideal sensor to facilitate in-vivo monitoring of the sub-bandage ...
Fukuda Takeshi - - 2013
Fasudil, a Rho-kinase inhibitor, has been shown to reduce portal venous pressure in cirrhotic rats. However, its effects on portal and systemic hemodynamics have not been investigated in cirrhotic patients with portal hypertension. The aim of this study was to assess the effects of fasudil on the portal and systemic ...
Sassani Sofia G - - 2013
Arteriovenous fistulae have been previously created by our group, through implantation of e-PTFE grafts between the carotid artery and jugular vein in healthy pigs, to gather comprehensive data on the time-course of the adapted geometry, composition, and biomechanical properties of the venous wall exposed to chronic increases in pressure and ...
Czyżowski J - - 2013
Even though much has been written on the aetiology of globus pharyngeus, itstill remains elusive and multifactorial. We present a case of a 54-year-old womanwho was referred by an orthopedist to the radiology department with a 6-dayhistory of an intense feeling of "pressure" and "tightness" in the jugular notch.After performing ...
Piola Marco - - 2013
Saphenous vein (SV) graft disease represents an unresolved problem in coronary artery bypass grafting (CABG). After CABG, a progressive remodelling of the SV wall occurs, possibly leading to occlusion of the lumen, a process termed 'intima hyperplasia' (IH). The investigation of cellular and molecular aspects of IH progression is a ...
Wang Alvin Yi-Chou - - 2013
Balloon test occlusion (BTO) is crucial before sacrificing parent arteries. We proposed a simple paradigm combining clinical tolerance with venous phase technique and stump pressure ratio as a criterion for sufficient collateral flow. Internal carotid artery (ICA) occlusion was considered safe for asymptomatic patients who exhibited less than 2 seconds of ...
Varble Nicole - - 2013
Experimental modeling of arteriovenous hemodialysis fistula (AVF) hemodynamics is challenging. Mathematical modeling struggles to accurately represent the capillary bed and venous circulation. In vivo animal models are expensive and labor intensive. We hypothesized that an in vitro, physiologic model of the extremity arteriovenous circulation with provisions for AVF and distal revascularization and ...
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