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Results 301 - 350 of 943
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Billecke S S - - 2011
The challenge of managing hypertension is exemplified by the limited success of monotherapy and necessity for multiple drug regimens targeting complimentary pathways. Recent evidence suggests that combination therapy including angiotensin-converting enzyme (ACE) inhibitors and calcium channel blockers (CCBs) provides blood pressure control while reducing cardiovascular mortality and morbidity over ACE ...
Fearn Cindy L - - 2011
This pilot study assessed knowledge of blood pressure among employees in a midwestern manufacturing plant. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guidelines were used to define blood pressure categories. The Roy Adaptation Model served as the ...
Handler Joel - - 2011
Compared with the history of national guideline development, the science attached to implementation of guidelines is relatively new. Effectiveness of a highly evidence-based guideline, such as the 8th Joint National Committee recommendations on the treatment of high blood pressure, depends on successful translation into clinical practice. Implementation relies on several ...
Jelin Eric B - - 2011
Congenital diaphragmatic hernia (CDH) is associated with significant neonatal morbidity and mortality. Although prenatal complete tracheal occlusion (cTO) causes hypoplastic CDH lungs to enlarge, improved lung function has not been demonstrated. Furthermore, cTO interferes with the dynamic pressure change and fluid flow associated with fetal breathing. The purpose of the ...
Vaishampayan Ashwini - - 2011
The objectives of the study were to sensitize practitioners working with individuals with spinal cord injury (SCI) to the complex life circumstances that are implicated in the development of pressure ulcers (PrUs) and to document the ways that interventions can be adapted to target individual needs. This study was a ...
Peinemann Frank - - 2011
In negative-pressure wound therapy (NPWT), a wound is covered with an airtight dressing, and negative pressure is applied. This is thought to promote healing. We evaluated NPWT with an updated, systematic review of the literature. We systematically searched the PubMed and Cochrane Library databases for randomized, controlled trials (RCTs) of ...
Sukor Norlela - - 2011
Hypertension is a very common disease, leading to significant morbidity with reduction in quality of life. In addition to being a major cause of morbidity and mortality, hypertension places a heavy burden on health care systems, families, and society as a whole. In patients with hypertension, the ability to identify ...
Pintérová M - - 2011
Essential hypertension is a multifactorial disorder which belongs to the main risk factors responsible for renal and cardiovascular complications. This review is focused on the experimental research of neural and vascular mechanisms involved in the high blood pressure control. The attention is paid to the abnormalities in the regulation of ...
Axelsson Michael - - 2011
In 1960, C.G. Wilber in a laboratory-based study described for the first time the changes in heart rate with submergence in the American alligator noting in particular the marked bradycardia that occurred during forced dives. This short review summarizes the major advances in our understanding of diving and the responses ...
Balmert Stephen C - - 2011
For the development and implementation of primary human cell- and stem cell-based applications in regenerative medicine, large amounts of cells with well-defined characteristics are needed. Such cell quantities can be obtained with the use of hollow fiber-based bioreactors. While the use of such bioreactors generally requires a perfusion circuit, the ...
Heeringa Rhea - - 2011
AIMS: To describe the bladder sensations experienced during non-invasive rapid bladder filling in a controlled setting in healthy volunteers. METHODS: Three groups of healthy volunteers, total 11 subjects (4 men, 7 women), participated in three consecutive focus group sessions. Before each session a strict water loading protocol was given. The ...
Li Zong-Ming - - 2011
Carpal tunnel mechanics is relevant to our understanding of median nerve compression in the tunnel. The compliant characteristics of the tunnel strongly influence its mechanical environment. We investigated the distensibility of the carpal tunnel in response to tunnel pressure. A custom balloon device was designed to apply controlled pressure. Tunnel ...
Sit Arthur J - - 2011
Episcleral venous pressure (EVP) is an important determinant of intraocular pressure (IOP) and can be measured by using various techniques. It has been measured non-invasively by estimating the pressure required to compress an episcleral vein to a predetermined endpoint. However, the lack of objective endpoints makes EVP measurement in humans ...
Chen Yun-Yun - - 2011
This research proposes an issue that has previously been omitted in flow field temperature reconstruction by optical computerized tomography (OCT). To prove that it is not reasonable to always assume an isobaric process occurs when OCT is adopted to obtain the temperature distributions of flow fields, a propane-air flame and ...
Wang Jing - - 2011
To examine whether there were long-term (between 1988-1994 and 2001-2008) and recent (between 2001-2004 and 2005-2008) changes in blood pressure (BP) levels among U.S. adults with diagnosed diabetes. Using data from National Health and Nutrition Examination Surveys (NHANES), we examined changes in BP distributions, mean BPs, and proportion with BP<140/90 ...
McMahon Malcolm I - - 2011
The ability of pressure to change inter-atomic distances strongly leads to a wide range of pressure-induced phenomena at high pressures: for example metallisation, amorphisation, superconductivity and polymerisation. Key to understanding these phenomena is the determination of the crystal structure using x-ray or neutron diffraction. The tools necessary to compress matter ...
Gor Gennady Yu - - 2011
We present a theoretical study of the deformation of mesoporous solids during adsorption. The proposed thermodynamic model allows one to link the mechanical stress and strain to the solvation pressure exerted by the adsorbed molecules on the pore wall. Two approaches are employed for calculation of solvation pressure as a ...
Seekins Megan B - - 2011
Objective - To review the use of impedance threshold devices (ITD) during CPCR, their proposed mechanism of action, and their application in veterinary medicine. Data Sources - Data sources include scientific reviews and original research publications using the PubMed search engine with the following keywords: 'impedance threshold device' and 'resuscitation' ...
Corrêa Ana Paula - - 2011
This study aimed to investigate the impact of seven environmental stressors (role conflict, work overload, interpersonal difficulties, work-family conflict, work instability, lack of autonomy and pressure of responsibility) and the nature of the employment contract (permanent or atypical) on three psychological reactions to occupational stress (job satisfaction, positive emotions, and ...
Ogunyankin Kofo O - - 2011
Abnormal diastolic function portends a poor prognosis regardless of any associated systolic dysfunction. There is controversy regarding the precision with which diagnosis of diastolic dysfunction can be made non-invasively. Clinical studies show that non-invasive evaluation of the severity of diastolic function predicts the risk of cardiac death and heart failure ...
Helton Kristen L - - 2011
This article is the second part of a two-part review in which we explore the biomechanics of the sensor-tissue interface as an important aspect of continuous glucose sensor biocompatibility. Part I, featured in this issue of Journal of Diabetes Science and Technology, describes a theoretical framework of how biomechanical factors ...
Mecoli Christopher A - - 2011
Symptomatic dermatographism reflects an exaggerated cutaneous response to the physical stimulus of pressure. Some consider it a common type of childhood physical urticaria. Its etiology can vary widely from drug reactions and infectious agents to systemic diseases and genetic inheritance. The mechanism is thought to be related to histamine degranulation ...
Gurley Susan B - - 2011
Hypertension affects more than 1.5 billion people worldwide but the precise cause of elevated blood pressure (BP) cannot be determined in most affected individuals. Nonetheless, blockade of the renin-angiotensin system (RAS) lowers BP in the majority of patients with hypertension. Despite its apparent role in hypertension pathogenesis, the key cellular ...
Boulogne F - - 2011
We simulate quasistatic flows of an ideal two-dimensional monodisperse foam around different obstacles, both symmetric and asymmetric, in a channel. We record both pressure and network contributions to the drag and lift forces and study them as a function of obstacle geometry. We show that the drag force increases linearly ...
Giday Araya - - 2011
Hypertension is an important public health challenge in both economically developed and developing countries. To asses the magnitude of hypertension in rural and urban southern Ethiopia. A cross sectional survey was conducted on 979 study participants in Sidama Zone, South Ethiopia from November 1-30, 2008. Data were collected using a ...
Nelson Mark - - 2011
Should you be using that new blood pressure device on your desk - or is it still in its box? Feedback from focus group sessions suggested that general practitioners were suspicious of the oscillometric blood pressure devices distributed by the High Blood Pressure Research Council of Australia (HBPRCA) as they ...
Parshad O - - 2011
Yoga improves cardiovascular health in both healthy individuals and those with diagnosed heart disease. This study compares changes in some cardiovascular parameters before and after the practice of Yoga in healthy medical students. Sixty-four healthy medical students (57 females and 7 males), mean age 21.3 +/- 2.6 years, attending a ...
He Zheng - - 2011
Although intraocular pressure (IOP) remains an important risk factor for glaucoma, it is clear that other factors can also influence disease development and progression. More recently, the role that blood pressure (BP) has in the genesis of glaucoma has attracted attention, as it represents a clinically modifiable risk factor and ...
Wood Benjamin C - - 2011
Subatmospheric pressure (SAP) therapy has evolved as a mainstay in the treatment of acute and chronic wounds over the past 20 years. The significant improvement in wound healing upon application of a SAP therapy system such as the Vacuum Assisted Closure (V.A.C.; KCI, San Antonio, TX) device, historically has been ...
Nauli Surya M - - 2011
Local regulation of vascular tone plays an important role in cardiovascular control of blood pressure. Aside from chemical or hormonal regulations, this local homeostasis is highly regulated by fluid-shear stress. It was previously unclear how vascular endothelial cells were able to sense fluid-shear stress. The cellular functions of mechanosensory cilia ...
Okehialam B N - - 2011
Hypertension treatment has been plagued by poor control globally;1 resulting in an ever increasing morbidity and mortality from the disease. To improve blood pressure control, it is important to understand the various issues impacting on it. As this may have socio-cultural undertones, it is recommended that the subject be looked ...
Verdonck Pascal - - 2011
A fluid is a medium which deforms, or undergoes motion, continuously under the action of a shearing stress and includes liquids and gases. Applying biofluid mechanics to the cardiovascular system requires knowledge of anatomy and geometry, pressure data and blood flow, volume and velocity measurements. A good example is the ...
Steppan Jochen - - 2011
Aging leads to a multitude of changes in the cardiovascular system, including systolic hypertension, increased central vascular stiffness, and increased pulse pressure. In this paper we will review the effects of age-associated increased vascular stiffness on systolic blood pressure, pulse pressure, augmentation index, and cardiac workload. Additionally we will describe ...
Kshatriya Shilpa - - 2011
Leptin is a 16-kDa-peptide hormone that is primarily synthesized and secreted by adipose tissue. One of the major actions of this hormone is the control of energy balance by binding to receptors in the hypothalamus, leading to reduction in food intake and elevation in temperature and energy expenditure. In addition, ...
Huang Lei - - 2011
Traumatic brain injury (TBI) is a major public health issue. The complexity of TBI has precluded the use of effective therapies. Hyperbaric oxygen therapy (HBOT) has been shown to be neuroprotective in multiple neurological disorders, but its efficacy in the management of TBI remains controversial. This review focuses on HBOT ...
Warnock James N - - 2011
The study aimed to identify mechanosensitive pathways and gene networks that are stimulated by elevated cyclic pressure in aortic valve interstitial cells (VICs) and lead to detrimental tissue remodeling and/or pathogenesis. Porcine aortic valve leaflets were exposed to cyclic pressures of 80 or 120 mmHg, corresponding to diastolic transvalvular pressure in ...
Michell Danielle L - - 2011
Essential hypertension is the leading risk factor for mortality worldwide, accountable for 13% of deaths globally. Despite numerous therapies available uncontrolled hypertension is still very prevalent today and a large subset are shown to have treatment resistant hypertension. Several cardiovascular diseases including hypertension result in endothelial dysfunction and inflammation. Once ...
Mahmoud Ramadan A - - 2011
Noninvasive ventilation is increasingly used in newborns, but intubation and mechanical ventilation remain important lifesaving tools for neonatal intensive care. New lung-protective mechanical ventilation technologies were developed in the last few decades and are now commercially available. Nevertheless, a recent survey (van Kaam et al. J Pediatr 2010) reported that ...
Schweda F - - 2011
The renin-angiotensin system (RAS) is critically involved in the regulation of the salt and volume status of the body and blood pressure. The activity of the RAS is controlled by the protease renin, which is released from the renal juxtaglomerular epithelioid cells into the circulation. Renin release is regulated in ...
van Kaam Anton - - 2011
Ventilator-induced lung injury (VILI) is considered an important risk factor in the development of bronchopulmonary dysplasia (BPD) and is primarily caused by overdistension (volutrauma) and repetitive opening and collapse (atelectrauma) of terminal lung units. Lung-protective ventilation should therefore aim to reduce tidal volumes, and recruit and stabilize atelectatic lung units ...
Shah Rajiv - - 2011
Glaucoma is characterised by progressive optic neuropathy and peripheral visual field loss. It affects 1% to 2% of white people aged over 40 years and accounts for 8% of new blind registrations in the UK. The main risk factor for glaucoma is raised intraocular pressure, but 40% of people with ...
Papademetriou Vasilios - - 2011
Interventional activation of the carotid baroreflex has been an appealing idea for the management of resistant hypertension for several decades, yet its clinical application remained elusive and a goal for the future. It is only recently that the profound understanding of the complex anatomy and pathophysiology of the circuit, combined ...
Coffman Thomas M - - 2011
High blood pressure, or hypertension, is a very common disorder with a substantial impact on public health because of its associated complications. Despite the high prevalence of essential hypertension and years of research, the basic causes remain obscure. Here I review recent advances in understanding the pathophysiology of hypertension. I ...
Tabassum Nahida - - 2011
Hypertension (HTN) is the medical term for high blood pressure. It is dangerous because it makes the heart work too hard and contributes to atherosclerosis (hardening of arteries), besides increasing the risk of heart disease and stroke. HTN can also lead to other conditions such as congestive heart failure, kidney ...
Forni Valentina - - 2011
In this review, we discuss the pharmacological and clinical properties of irbesartan, a noncompetitive angiotensin II receptor type 1 antagonist, successfully used for more than a decade in the treatment of essential hypertension. Irbesartan exerts its antihypertensive effect through an inhibitory effect on the pressure response to angiotensin II. Irbesartan ...
Palatini Paolo - - 2011
This review summarizes several scientific contributions at the recent Satellite Symposium of the European Society of Hypertension, held in Milan, Italy. Arterial stiffening and its hemodynamic consequences can be easily and reliably measured using a range of noninvasive techniques. However, like blood pressure (BP) measurements, arterial stiffness should be measured ...
Hammami Sonia - - 2011
Hypertension is a cardiovascular disorder rapidly emerging as a major public health problem in developing countries. However, the acknowledgement of the prevalence and the significant impact of hypertension in elderly are very important for health policy. The objective of the present investigation was to evaluate the prevalence, awareness and treatment ...
Koeppen Michael - - 2011
Murine models are extensively used to investigate acute injuries of different organs systems. Acute lung injury (ALI), which occurs with prolonged mechanical ventilation, contributes to morbidity and mortality of critical illness, and studies on novel genetic or pharmacological targets are areas of intense investigation. ALI is defined by the acute ...
Xin Xiaorong - - 2011
Meningothelial cells (MECs) are the cellular components of the meninges enveloping the brain. Although MECs are not fully understood, several functions of these cells have been described. The presence of desmosomes and tight junctions between MECs hints towards a barrier function protecting the brain. In addition, MECs perform endocytosis and, ...
Fenger Mogens - - 2011
Several attempts to decipher the genetics of hypertension of unknown causes have been made including large-scale genome-wide association analysis (GWA), but only a few genes have been identified. Unsolved heterogeneity of the regulation of blood pressure and the shortcomings of the prevailing monogenic approach to capture genetic effects in a ...
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