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Singh Jagjit - - 2012
The hypertensive emergencies in haemodialysis require immediate therapy, usually by parenteral drug administration; however, sublingual medications may have a potential in this special condition. A prospective, non randomized, case control study was carried out to know the effectiveness and the safety of a single dose of 5mg Nifedipine (sublingual) in ...
Koenig Walter D - - 2013
Abstract The extraordinarily long life cycles, synchronous emergences at 13- or 17-year intervals, and complex geographic distribution of periodical cicadas (Magicicada spp.) in eastern North America are a long-standing evolutionary enigma. Although a variety of factors, including satiation of aboveground predators and avoidance of interbrood hybridization, have been hypothesized to ...
Karakiliç E - - 2012
Hypertensive crisis is a condition characterized by rapid and inappropriate symptomatic elevation of blood pressure (BP) that is commonly seen in Emergency Departments. Oral or sublingual captopril is commonly used in the Emergency Departments. The unpleasant taste of the sublingual drugs causes uncomfortable condition to the patient. Studies showing no ...
Merlin Mark A - - 2012
Loading of thiamine prior to glucose administration during hypoglycemia to prevent Wernicke's encephalopathy is routine in the prehospital setting. To date no study has looked at the validity of this therapy. We evaluated a retrospective cohort of 242 patients who received intravenous glucose for hypoglycemia comparing those who received thiamine ...
Paksu Muhammet Sükrü - - 2012
Tetrahydrozoline is a commonly used imidazoline derivative with serious side effects and toxicity, particularly in small children. A one-year-old boy was admitted to the emergency department (ED) after he accidentally ingested about half a bottle of nasal decongestant solution containing tetrahydrozoline. He was unconscious, hypothermic and bradycardic on presentation. His ...
Nagashima Kazuki - - 2012
This study demonstrates the effect of surroundings on a memristive switching at nanoscale by utilizing an open top planar-type device. NiO(x) and CoO(x) planar-type devices have exhibited a memristive behavior under atmospheric pressure, whereas TiO(2-x) planar-type devices did not show a memristive switching even under the same surroundings. A memristive ...
Johnson Wallace - - 2012
Hypertensive crises, which include hypertensive emergencies and urgencies, are frequently encountered in the emergency department, and require immediate attention as they can lead to irreversible end-organ damage. Normal blood pressure (BP) regulation is altered during acute rises in BP, leading to end-organ damage. Multiple organs can be injured. Special considerations ...
Tsze Daniel S - - 2012
ABSTRACT: We describe a 4-year-old boy who presents to the emergency department with lethargy, bradycardia, and initial hypertension followed by hypotension due to guanfacine toxicity after ingestion of standard doses of the extended release formulation. This is the first case report to describe the use of naloxone to treat these ...
El-Khatib Mohamad F - - 2012
Noninvasive positive pressure ventilation is increasingly being used in emergency departments across Europe and North America. To our knowledge, no similar data are available from other countries. The aim of this study is to describe the current use of noninvasive positive pressure ventilation in the emergency departments of Lebanese hospitals. ...
Yashima M - - 2012
We report on a pressure-induced evolution of exotic superconductivity and spin correlations in CeIr(In_{1-x}Cd_{x})_{5} by means of in-nuclear-quadrupole-resonance (NQR) studies. Measurements of an NQR spectrum and nuclear-spin-lattice-relaxation rate 1/T_{1} have revealed that antiferromagnetism induced by Cd doping emerges locally around Cd dopants, but superconductivity is suddenly induced at T_{c}=0.7 and ...
Dasari Prasad L V K - - 2012
Static high pressure lithium amide (LiNH2) crystal structures were predicted using evolutionary structure search methodologies and intuitive approaches. In the process, we explored the relationship of the structure and properties of solid LiNH2 to its molecular monomer and dimer, as well as its valence-isoelectronic crystalline phases of methane, water, and ...
Xu Tan - - 2012
J Clin Hypertens (Greenwich). 2012;14:787-791. ©2012 Wiley Periodicals, Inc. During the past decades, blood pressure (BP) measurement technique has evolved rapidly from the traditionally manual measuring to fully automatic monitoring. In terms of management of BP, there have been tremendous changes from the controlling of daytime BP, nondipping pattern to ...
Wall Colin - - 2012
Snake-bite is a significant problem worldwide. Despite frequent deployments and exercises to countries where venomous snakes are endemic there are few reported cases of British Army personnel being bitten. Clinical Guidelines for Operations includes direction on the treatment of snakebite, including the application of pressure immobilisation. This article reviews the ...
Tamez Hector - - 2012
Vitamin D deficiency and hypertension are highly prevalent. This review will discuss the association between vitamin D deficiency and blood pressure. During the past several years multiple prospective cohorts and randomized studies have been published. Recent studies have focused mostly on 25-hydroxy vitamin D, but a small number of trials ...
Nandi Mahasweta - - 2012
Highly porous N-doped activated carbon monoliths (ACMs) are fabricated by carbonization and physical activation of mesoporous polyacrylonitrile (PAN) monoliths in the presence of CO(2). The monoliths exhibit exceptionally high CO(2) uptake; 5.14 mmol g(-1) at ambient pressure and temperature and 11.51 mmol g(-1) at ambient pressure and 273 K.
Krajewska Barbara - - 2012
Urease, a Ni-containing metalloenzyme, features an activity that has profound medical and agricultural implications. The mechanism of this activity, however, has not been as yet thoroughly established. Accordingly, to improve its understanding, in this study we analyzed the steady-state kinetic parameters of the enzyme (jack bean), K (M) and k ...
Chattillion Elizabeth A EA Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, - - 2013
A combination of high engagement in pleasurable activities and low perceived activity restriction is potentially protective for a number of health and quality of life outcomes. This study tests the newly proposed Pleasant Events and Activity Restriction (PEAR) model to explain level of blood pressure (BP) in a sample of ...
Boivin Benoit B Montreal Heart Institute, 5000 Belanger St., Montreal, QC, H1T 1C8, - - 2012
Chronic hemodynamic overload results in left ventricular hypertrophy, fibroblast proliferation, and interstitial fibrosis. The small heat shock protein hsp27 has been shown to be cardioprotective and this requires a phosphorylatable form of this protein. To further understand the regulation of hsp27 in heart in response to stress, we investigated the ...
Li Peng - - 2012
Central melanocortin 3/4 receptors (MC3/4R) are known to regulate energy balance. Activation of the MC3/4R causes greater increase in the firing activity of the PVN neurons in obese Zucker rats than in lean Zucker rats. The present study was to determine the roles of MC3/4R in hypothalamus paraventricular nucleus (PVN) ...
Huuppola Maija - - 2012
Iron nanoparticles were prepared by decomposing iron pentacarbonyl (Fe(CO)(5)) at 170-220°C in the presence of amine surfactant and alkane solvent and under 1-12bar carbon monoxide (CO) pressure. It was found that the amine not only acted as a stabilizer for the growing particles but also had a critical role as ...
Liu Ling - - 2012
ABSTRACT: INTRODUCTION: Based on the hypothesis that weaning failure from mechanical ventilation is caused by respiratory demand exceeding the capacity of the respiratory muscles, we evaluated whether extubation failure could be characterized by increased respiratory drive and impaired efficiency to generate inspiratory pressure and ventilation. METHODS: Airway pressure, flow, and ...
Vengiau Gwendalyn - - 2012
OBJECTIVES: Obesity and hypertension are increasing in Papua New Guinea. This study investigated the association of dietary pattern and physical activity level with anthropometric measurements and blood pressure in migrant Bougainvilleans in the capital city of Port Moresby. METHODS: Adults who had moved from Naasioi territory on Bougainville Island and ...
Mahmud Laura M G Meemsmegan V Cannonhasan - - 2012
BACKGROUND: Activation of the vitamin D-vitamin D receptor (VDR) axis has been shown to reduce blood pressure and left ventricular (LV) hypertrophy. Besides cardiac hypertrophy, cardiac fibrosis is a key element of adverse cardiac remodeling. We hypothesized that activation of the VDR by paricalcitol would prevent fibrosis and LV diastolic ...
Lohmeier Thomas E TE Department of Physiology, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS 39216, USA. - - 2012
Device-based therapy for resistant hypertension by electrical activation of the carotid baroreflex is currently undergoing active clinical investigation, and initial findings from clinical trials have been published. The purpose of this mini-review is to summarize the experimental studies that have provided a conceptual understanding of the mechanisms that account for ...
Fantin Francesco - - 2012
To date, only a few studies have evaluated the effect of physical activity on PWVcf in the elderly. In the current study, 21 community-dwelling women, with a mean age of 68.19±5.72 years and a mean BMI of 28.63±4.69 kg m(-2), participated in moderate physical activity sessions for 1 h per day and 2 ...
Iliescu Radu - - 2012
Chronic electric activation of the carotid baroreflex produces sustained reductions in sympathetic activity and arterial pressure and is currently being evaluated as hypertension therapy for patients with resistant hypertension. However, the chronic changes in renal function associated with natural suppression of sympathetic activity are largely unknown. In normotensive dogs, we ...
Blazquez A - - 2012
Although the circadian blood pressure (BP) pattern has been extensively studied, the determinants of this rhythm are not fully understood. Peripheral vasodilatation is a regulatory mechanism for BP maintenance. However, it remains to be established whether the increase of nocturnal distal skin temperature associated with heat loss could also reflect ...
Lauterburg Meret - - 2012
OBJECTIVE: Renal allograft donors are at risk to develop hypertension. Here we hypothesized that this risk is at least in part explained by an enhanced intracellular availability of 11β-hydroxyglucocorticoids due to an increased 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), an intracellular prereceptor activator of biologically inactive 11-ketocorticosteroids in the liver ...
Raheja Prafull - - 2012
Recent studies from our laboratory indicate that chlorthalidone triggers persistent activation of the sympathetic nervous system and promotes insulin resistance in hypertensive patients, independent of serum potassium. Mechanisms underlying these adverse effects of chlorthalidone remain unknown, but increasing evidence in rodents suggests the role of angiotensin and aldosterone excess in ...
Bruno Rosa M - - 2012
BACKGROUND: Essential hypertension is characterized by both increased oxidative stress and sympathetic traffic. Experimental studies have shown that reactive oxygen species can modulate autonomic activity. OBJECTIVE: The aim of this study was to determine whether acute administration of the antioxidant vitamin C modifies sympathetic nerve activity in essential hypertension. DESIGN: ...
Wang Mingyi - - 2012
Age-associated arterial remodeling involves arterial wall collagen deposition and elastin fragmentation, as well as an increase in arterial pressure. This arterial remodeling is linked to proinflammatory signaling, including transforming growth factor-β1, monocyte chemoattractant protein 1, and proendothelin 1, activated by extracellular matrix metalloproteinases (MMPs) and orchestrated, in part, by the ...
Cheng J-G - - 2012
We report a comprehensive high-pressure study on the triple-layer T^{'}-La_{4}Ni_{3}O_{8} with a suite of experimental probes, including structure determination, magnetic, and transport properties up to 50 GPa. Consistent with a recent ab inito calculation, application of hydrostatic pressure suppresses an insulator-metal spin-state transition at P_{c}≈6  GPa. However, a low-spin metallic phase does not ...
Cypess Aaron M - - 2012
As potential activators of brown adipose tissue (BAT), mild cold exposure and sympathomimetic drugs have been considered as treatments for obesity and diabetes, but whether they activate the same pathways is unknown. In 10 healthy human volunteers, we found that the sympathomimetic ephedrine raised blood pressure, heart rate, and energy ...
Garver Jennifer - - 2012
ABSTRACT Radiotelemetry allows for real-time remote monitoring of biological parameters in freely moving laboratory animals. The HD-X11 transmitter is a novel telemetry device that enables simultaneous collection of body temperature, activity, blood pressure, electrocardiogram (ECG), and other biopotentials in small animal models. Previously, researchers could only collect either blood pressure ...
Nakamizo Hiromasa - - 2012
Although increased intraluminal pressure in the stomach due to gastric outlet obstruction or functional gastric motor dysfunction, including gastroparesis, may affect gastric mucosal integrity, the direct effect of mechanical pressure on gastric mucosal cells has not yet been fully investigated. The aims of this study were to determine whether exposure ...
Wuerzner Gregoire - - 2012
The prevalence of both hypertension and vitamin D deficiency is high. The discovery of the vitamin D receptor and its possible effects on components of the cardiovascular system influencing blood pressure, such as the renin angiotensin system, the heart, the kidney and the blood vessels, has generated the hope that ...
Shoemaker J Kevin - - 2012
Cardiovascular arousal is associated with patterned cortical activity changes. Head-down tilt bed rest dimishes baroreflex-mediated cardiac control. The present study tested the hypothesis that head-down bed rest deconditioning would modify the forebrain organization for heart rate control during baroreflex unloading. Heart rate (HR) variability (HRV), blood pressure and plasma hormones ...
Demir Mehmet - - 2012
Nondipper hypertension is associated with increased cardiovascular morbidity and mortality. Vitamin D deficiency is associated with cardiovascular diseases such as coronary artery disease, heart failure, and hypertension. Vitamin D deficiency activates the renin-angiotensin-aldosterone system, which affects the cardiovascular system. For this reason, a relationship between vitamin D deficiency and nondipper ...
Grønbaek H - - 2012
BACKGROUND: Activation of Kupffer cells may be involved in the pathogenesis of portal hypertension by release of vasoconstrictive substances and fibrosis due to co-activation of hepatic stellate cells. AIM: To study soluble plasma (s) CD163, a specific marker of activated macrophages, as a biomarker for portal hypertension in patients with ...
Kohli Nupur R - - 2012
OBJECTIVE:: To investigate the role of vitamin D in explaining ethnic differences in blood pressure among three ethnic groups in the Netherlands (ethnic Dutch, African Surinamese, and south Asian Surinamese). METHODS:: Data were derived from the 'Surinamese in the Netherlands: study on ethnicity and health' study, a population-based observational study. ...
Hervás Daniel - - 2012
BACKGROUND:: The factors that determine the initiation and persistence of yearly epidemics of respiratory syncytial virus (RSV) bronchiolitis are not well known. A limited number of studies have found that meteorologic conditions could be associated with RSV activity. OBJECTIVES:: We analyze the association of certain atmospheric conditions to RSV activity, ...
Zhou Yan - - 2012
BACKGROUND: Information is limited about the correlation between cardiovascular risk factors (CRFs) and autonomic nervous system (ANS) activity in children. METHODS: In all, 180 children aged 9 to 11 years were enrolled. Heart rate variability, obtained by 24-hour Holter recordings, was analyzed for ANS activity by measuring standard deviation of ...
Tang Kit Tzu - - 2012
Prostheses are prescribed to restore the mobility of people with amputated lower limbs. Monitoring the prosthesis wearing times and physical activity of prosthesis users would provide invaluable information regarding rehabilitation progress and suitability of the prosthesis. The validation of a method to determine wearing times and physical activity state, as ...
Kolt Gregory S - - 2012
We compared the effectiveness of 2 physical activity prescriptions delivered in primary care--the standard time-based Green Prescription and a pedometer step-based Green Prescription--on physical activity, body mass index (BMI), blood pressure, and quality of life in low-active older adults. We undertook a randomized controlled trial involving 330 low-active older adults ...
Hadj-Ahmed Mohamed Amine - - 2012
In nonsedated newborn lambs, nasal pressure support ventilation (nPSV) can lead to an active glottal closure in early inspiration, which can limit lung ventilation and divert air into the digestive system, with potentially deleterious consequences. During volume control ventilation (nVC), glottal closure is delayed to the end of inspiration, suggesting ...
Rietveld Ivo B - - 2012
Enantiomer resolution is much sought after for pharmaceutical applications, because many optically active drug molecules have only one pharmaceutically active enantiomer. Although it is always possible to force separation, it will come at a cost. The present method, based on thermodynamics, provides a relatively easy approach to investigate whether separation ...
Jezowski Sebastian R - - 2012
The anthracene cyclophane bis-anthracene (BA) can undergo a [4+4] photocycloaddition reaction that results in a photodimer with two cyclobutane rings. We find that the subsequent dissociation of the dimer, which involves the rupture of two carbon-carbon bonds, is strongly accelerated by the application of mild pressures. The reaction kinetics of ...
Thethi Tina - - 2012
Obesity is a risk factor for type 2 diabetes mellitus (DM) and is associated with chronic kidney disease. Activation of the renin-angiotensin-aldosterone system (RAAS) is common in obesity. The RAAS is an important mediator of hypertension. Mechanisms involved in activation of the RAAS in obesity include sympathetic stimulation, synthesis of ...
Doumas Michael - - 2012
Carotid baroreceptors play an important role in blood pressure regulation through modification of sympathetic nervous activity. Conditions associated with increased sympathetic activity, such as resistant hypertension and heart failure, represent potential targets for carotid baroreceptor activation. Recent technological advances made available a small device, like a pacemaker, that constantly activates ...
Pedersen Karsten - - 2012
Pressure-resistant circulating systems were constructed to enable the investigation of attached and unattached microbial populations under in situ pressure (2.5 MPa), diversity, dissolved gas, and chemistry conditions. Three parallel-flow cell cabinets were configured to allow observation of the effect on microbial metabolic activity of adding 3 mM hydrogen or 2.4 ...
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