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Martin-StPaul N K NK CEFE UMR 5175, CNRS-Université de Montpellier-Université Paul-Valéry Montpellier-EPHE-IRD, 1919 route de Mende 34293 Montpellier Cedex 5, France Laboratoire Ecologie Systématique et Evolution CNRS, Orsay F-91405, France nico09.martin@gmail.com - - 2014
Three methods are in widespread use to build vulnerability curves (VCs) to cavitation. The bench drying (BD) method is considered as a reference because embolism and xylem pressure are measured on large branches dehydrating in the air, in conditions similar to what happens in nature. Two other methods of embolism ...
Fajemiroye James Oluwagbamigbe JO Department of Physiological Sciences, Federal University of Goiás, Campus Samambaia, 74001-970 Goiâania, GO, Brazil. Electronic address: - - 2014
Clinical complaints on the first-line of cardiovascular medications make continuous search for new drugs a necessity. This study evaluated the cardiovascular effects and mechanism of 4-[(1-phenyl-1H-pyrazol-4-yl)methyl]1-piperazine carboxylic acid ethyl ester (LQFM008). Normotensive male Wistar or spontaneously hypertensive rats (anesthetized or conscious) were used to evaluate the effect of LQFM008 on ...
Feldman Ross D RD Robarts Research Institute, London, ON, - - 2014
Activation of vascular GPER has been linked to vasodepressor effects in animals. However, the significance of GPER regulation on chronic blood pressure control in humans is unknown. To examine this question we determined the functional significance of expression of a common missense single nucleotide variant of GPER, P16L in vascular ...
Asmussen Sven S aDepartments of Anesthesiology, The University of Texas Medical Branch, Galveston, TX bDepartment of Clinical Science and Education, Karolinska Institutet, Section of Anaesthesiology and Intensive Care, Södersjukhuset, Stockholm, Sweden cDepartment of Internal Medicine, The University of Texas Medical Branch, Galveston, - - 2014
The primary goal of fluid therapy is to maintain fluid homeostasis. Commonly used isotonic crystalloids are only marginally effective and contribute to fluid excess syndrome. In patients with decreased cardiovascular reserve, fluid therapy alone is not sufficient to maintain end-organ perfusion. Therefore, inotropes or vasoactive drugs are used to supplement ...
Ruhhammer Johannes J Department of Microsystems Engineering, University of Freiburg, Georges-Koehler-Allee 102, 79110, Freiburg, Germany, - - 2014
A novel sensor for measuring arterial distension, pulse and pressure waveform is developed and evaluated. The system consists of a magnetic sensor which is applied and fixed to arterial vessels without any blood vessel constriction, hence avoiding stenosis. The measurement principle could be validated by in vitro experiments on silicone ...
Lee Ji-Hyun JH Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, #101 Daehak-ro, Jongno-gu, Seoul, 110-744, Republic of - - 2014
The aim of this study was to compare tissue oxygen saturation as measured by INVOS(®) and InSpectra™ during a vascular occlusion test (VOT) in the same subject. Twenty healthy adults were investigated. The INVOS(®) and InSpectra™ probes were placed randomly on the right and left thenar eminence in the same ...
Pozzobon Cesar Romaro CR Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, - - 2014
Background: Antihypertensive drugs are used to control blood pressure (BP) and reduce macro- and microvascular complications in hypertensive patients with diabetes. Objectives: The present study aimed to compare the functional vascular changes in hypertensive patients with type 2 diabetes mellitus after 6 weeks of treatment with amlodipine or losartan. Methods: ...
Raptis Athanasios E AE 2nd Department of Medicine-Propaedeutic Clinic, Research Institute, and Diabetes Centre, Athens University Medical School, Attikon University General Hospital, Haidari, Athens, Greece - - 2014
The aim of this study was to investigate the effects of aliskiren on vascular function and endothelial progenitor cells (EPCs) in patients with type 2 diabetes and essential hypertension. The study enrolled type 2 diabetic patients aged >50 years under stable glycemic control and first diagnosed mild essential hypertension. In ...
Wu Di D Institute of Pharmacy and Pharmacology, University of South China, Hengyang, 421001, - - 2014
Apelin is a recently described endogenous peptide and its receptor APJ, is a member of the G protein-coupled receptors family. Apelin and APJ are widely distributed in central and peripheral tissues exert important biological effects on cardiovascular system. Recent studies have suggested that apelin/APJ system involves in decreasing the blood ...
Bibi Shahida S 1 Division of Colon and Rectal Surgery, Advocate Lutheran General Hospital , Park Ridge, - - 2014
Abstract Background: Mesenteric vascular ligation is a critical step in minimally invasive colorectal surgery. This study assessed the quality of in vivo and ex vivo sealing of the human inferior mesenteric artery (IMA), as well as the relation of IMA stump and bursting pressure. Patients and Methods: This was a ...
Pollock Jonathan P JP Penn State Hershey Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, - - 2014
In response to hypoxia, a net vasodilation occurs in the limb vasculature in young healthy humans and this is referred to as "hypoxia-induced vasodilation". We performed two separate experiments to determine (1) if hypoxia-induced forearm vasodilation is impaired in older men (n = 8) compared to young men (n = ...
Momin A A Cardiothoracic Department, St George's Hospital, London, UK - - 2014
Hypertension is a risk factor for accelerated saphenous vein (SV) graft disease and endothelial dysfunction in a number of vascular territories. We examined the relationship between blood pressure (BP) and vascular function in SV from 94 male patients undergoing coronary artery bypass grafting (CABG). Patients were pretreated with respect to ...
Houston Mark M Hypertension Institute, Nashville, - - 2014
This blinded placebo-controlled crossover study evaluated the acute effects of an orally disintegrating lozenge that generates nitric oxide (NO) in the oral cavity on blood pressure (BP) response, endothelial function, and vascular compliance in unmedicated hypertensive patients. Thirty patients with clinical hypertension were recruited and enrolled in a blinded placebo-controlled ...
Kim Yong-Hoon YH Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong-gu, Daejeon, South - - 2014
Endothelial nitric oxide synthase (eNOS) is involved in blood pressure (BP) regulation through the production of nitric oxide. Sirtuin I (SIRT1), an NAD-dependent protein deacetylase, promotes vascular relaxation through deacetylation and activation of eNOS. β-Lapachone (βL) increases the cellular NAD(+)/NADH ratio by activating NAD(P)H:quinone oxidoreductase 1 (NQO1). In this study, ...
Weber Franz F St Walburga Hospital, Meschede, Private Practice at the Medical Care Center, Dialysis Center, - - 2014
The introduction of invasive treatments, some of which are irreversible, for the entity called treatment-resistant hypertension (TRH) creates the need for a comprehensive discussion of the diagnostic evaluation that TRH requires and the available options for its conservative treatment. The pertinent literature is selectively reviewed in the light of the ...
Barman Scott A SA From the Department of Forensic Medicine, Nanjing Medical University, Jiangsu, China (F.C.); Department of Pharmacology and Toxicology (S.A.B., Y.S., W.H., D.J.R.F.) and Vascular Biology Center (F.C., C.D., Y.W., J.D.S., N.B., O.R., R.R., S.M.B., D.W.S., G.R., D.J.R.F.), Georgia Regents University, Augusta; Vichem Chemie, Ltd, Budapest, Hungary (L.O., C.S.-K., G.K., I.S.); University of Leipzig, Leipzig, Germany (A.G.); Hannover Medical School, Hannover, Germany (D.J.); University of Texas Health Science Center at San Antonio (R.A.); and Pathobiochemical Research Group of Hungarian Academy of Sciences (G.K.) and Department of Pharmaceutical Chemistry (L.O.), Semmelweis University, Budapest, Hungary. sbarman@gru.edu dfulton@gru.edu - - 2014
Pulmonary hypertension (PH) is a progressive disease arising from remodeling and narrowing of pulmonary arteries (PAs) resulting in high pulmonary blood pressure and ultimately right ventricular failure. Elevated production of reactive oxygen species by NADPH oxidase 4 (Nox4) is associated with increased pressure in PH. However, the cellular location of ...
Deda Livia L 1Department of Endocrinology,Hospital for Sick Children,University of - - 2014
Reactive hyperemia index is a measure of endothelial function used to assess subclinical atherosclerosis. When evaluated in healthy adolescents, significant changes in endothelial function were correlated with advancing age, pubertal status, and blood pressure. Blood pressure was the principal contributor to reactive hyperemia index variability independent of age, lipid profile, ...
Hildebrandt Drew A DA From the Department of Physiology and Biophysics (D.A.H., T.E.L.) and Department of Surgery (D.A.H.), University of Mississippi Medical Center, Jackson; North Memorial Medical Center, Trauma Services, Robbinsdale, MN (E.D.I.); and CVRx, Inc, Minneapolis, MN - - 2014
Chronic electric activation of the carotid baroreflex produces sustained reductions in sympathetic activity and arterial pressure and is currently being evaluated as antihypertensive therapy for patients with resistant hypertension. However, the influence of variations in salt intake on blood pressure lowering during baroreflex activation (BA) has not yet been determined. ...
Yamashita Sumiyo S Department of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences , Nagoya , - - 2014
Objectives. The present study investigated whether brachial and central blood pressures have differential impact on the cardiovascular system in the general population. Methods. The study included 706 subjects (59 ± 10 years) who visited our hospital for a physical check-up. Brachial blood pressure and radial artery pressure waveforms were recorded ...
Calbet Jose Al JA Copenhagen Muscle Research Center, Rigshospitalet, section, 7652, Copenhagen, Denmark; Department of Physical Education, University of Las Palmas de Gran Canaria, Canary Islands, Spain; Research Institute of Biomedical and Health Sciences (IUIBS), Las Palmas de Gran Canaria, Canary Islands, - - 2014
To determine the role played by adenosine, ATP and chemoreflex activation on the regulation of vascular conductance in chronic hypoxia. The vascular conductance response to low and high doses of adenosine and ATP was assessed in ten healthy men. Vasodilators were infused into the femoral artery at sea level and ...
Patwardhan V R VR Beth Israel Deaconess Medical Center, Boston, MA, - - 2014
Portal hypertensive gastropathy (PHG) and gastric antral vascular ectasia (GAVE) are important causes of both acute and chronic gastrointestinal bleeding in patients with cirrhosis. To review the current management of PHG and GAVE. PubMed was searched for English language articles using the key words 'GAVE', 'gastric antral vascular ectasia', 'cirrhosis', ...
Matz Brad M BM Department of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, - - 2014
To determine the effectiveness of a vascular sealing technology on canine carotid arteries using various seal configurations to achieve maximal vessel security. Ex-vivo study. Dogs (n = 20). Carotid arteries (n = 40) were removed from the mid-cervical region of recently euthanatized dogs. Harvested vessels were closed with 2 circumferential ligatures (Group 1) or ...
Harsanji-Drenjancevic Ines I University of Osijek Department of Physiology and Immunology, Faculty of Medicine J. Huttlera 4 31000 Osijek Croatia University of Pécs Pécs - - 2014
The control of arterial pressure is a complex interaction of the long- and short-term influences of hormones, local vascular factors, and neural mechanisms. The autonomic nervous system and its sympathetic arm play important roles in the regulation of blood pressure, and overactivity of sympathetic nerves may have an important role ...
Lee Joshua F - - 2014
A high degree of interindividual variability exists in the magnitude of heat stress (HS)-induced reductions in orthostatic tolerance relative to normothermia (NT). This variability may be associated with HS-mediated reductions in cerebral perfusion (indexed as middle cerebral artery blood velocity; MCAV(mean)) and altered cerebrovascular regulation. We tested the hypothesis that ...
Akal Ali A Department of Ophthalmology, Harran University, Sanlıurfa, - - 2014
Background and Aim: Resistive index (RI) is an indirect measurement of blood flow resistance that can be used to evaluate vascular damage in ophthalmologic disease. The purpose of this study was to evaluate the association between RI values of orbital arteries using the color Doppler imaging (CDI) in geriatric hypertensive ...
Rigatelli Gianluca G Cardiovascular Diagnosis and Endoluminal Interventions, Rovigo General Hospital, Rovigo, - - 2014
To assess the impact on stent implantation rate and mid-term outcomes of prolonged high pressure angioplasty of femoropopliteal lesions. We retrospectively enrolled 620 consecutive patients from January 2011 to December 2011 (75.6 ± 12.3 years, 355 males, 76.5% in Rutherford class 5-6), referred for critical limb ischemia and submitted to ...
Lee HaNa H Division of Neonatology IS, Hauner Dr. von Hauner Children's Hospital, University of Munich, Munich, - - 2014
Increased carotid intima-media thickness (cIMT) and loss of capillary density are antecedents of cardiovascular disease in adults. Former preterm infants are at risk for metabolic precursors of vascular disease, but vascular changes have not yet been studied in this population. In 54 former preterm (birth weigh (BW) 753±152 g) and 12 ...
Guyette Jacques P JP 1] Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA. - - 2014
The native extracellular matrix (ECM) outlines the architecture of organs and tissues. It provides a unique niche of composition and form, which serves as a foundational scaffold that supports organ-specific cell types and enables normal organ function. Here we describe a standard process for pressure-controlled perfusion decellularization of whole organs ...
Barbour Jayne A JA Nutrition Physiology Research Centre, Sansom Institute for Health Research, University of South Australia,GPO Box - - 2014
Nuts are rich in many nutrients that can benefit multiple cardiometabolic functions, including arterial compliance, blood pressure, inflammation, glucoregulation and endothelial vasodilatation. Impaired vasodilatation may contribute to impaired cognitive performance due to poor cerebral perfusion. The present narrative review examines associations between nut consumption, vascular health and cognitive function. It ...
Marchi Katia Colombo KC Katia Colombo Marchi, Programa de pós-graduação em Farmacologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, CEP 14040-900, - - 2014
The influences of life habits on the cardiovascular system may have important implications for public health, as cardiovascular diseases are among the leading causes of shorter life expectancy worldwide. A link between excessive ethyl alcohol (ethanol) consumption and arterial hypertension was first suggested early last century. Since then, this proposition ...
Edwards Martin O MO Department of Child Health, School of Medicine, Cardiff University, Cardiff, - - 2014
Preterm birth, low birth weight and poor fetal nutrition have been linked to cardiovascular disease, but the underlying mechanisms remain unclear. We explored prematurity and vascular function by studying a UK cohort of 14,049 children and conducting a systematic review. Systolic blood pressure was higher in subjects born preterm than ...
Yin Anlin A College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, - - 2014
In the vascular prosthetic field, the prevailing thought is that for clinical, long-term success, especially bioresorbable grafts, cellular migration and penetration into the prosthetic structure is required to promote neointima formation and vascular wall development. In this study, we fabricated poly (l-lactic acid-co-ɛ-caprolactone) P(LLA-CL)/silk fibroin (SF) vascular scaffolds through electrospinning ...
Tempark Therdpong T Department of Pediatrics, Chulalongkorn University, Bangkok, - - 2014
The clinical presentation of arborizing vascular dilatation can resemble Lichtenberg figures from lightning. Both have a feather-like or ferning pattern. We report an interesting case of pressure-induced vasodilatation (PIV) caused by temporary vascular occlusion from jeans buttons.
Endo Masako Y - - 2014
Recently, it was reported in healthy young subjects that fructose containing drinks increased blood pressure acutely, without any apparent change in total vascular conductance (TVC). However, because it is well known that the splanchnic vasculature is dilated by oral fructose ingestion, it is assumed to be the concomitant vasoconstriction in ...
Fajemiroye James O JO Department of Physiological Sciences, Federal University of Goiás, Campus Samambaia, 74001-970, Goiânia-GO, Brazil. Electronic address: - - 2014
Application of naturally occurring (E) - methyl isoeugenol (MIE) as food flavour has been widely accepted despite the growing concerns over cardiovascular issue. Hence, we sought to investigate hypotensive property of MIE and the involvement of central and/or peripheral mechanism (s). Variation in mean arterial pressure (MAP), heart rate (HR), ...
Kotliar Carol C Centre of Hypertension, Cardiology Service, Hospital Universitario Austral, Argentina - - 2014
The relationship between salt intake, blood pressure and RAAS activation is still controversial, being that both high- and low-salt intakes are associated with cardiovascular events in a J-shaped curve pattern. We hypothesized that different patterns of RAAS response to dietary salt intake among hypertensives could be identified, while vascular damage ...
Wang H H Department of Vascular Medicine, Peking University Shougang Hospital, Beijing, - - 2014
An increasing of arterial stiffness is the path physiological characteristic of hypertension. Cardio-ankle vascular index (CAVI) is a new index of arterial stiffness. In the present study, we investigated the relationship between CAVI and plasma lipids in hypertension subjects. A total of 542 subjects (male/female 336/206) from the Department of ...
Gavalas M V MV Stony Brook University Hospital, Department of Surgery, Division of Vascular Surgery, Stony Brook, NY, USA - - - 2014
Evaluate the short and longterm outcomes of percutaneous transluminal angioplasty in patients with hypertension and renal artery fibromuscular dysplasia (FMD) and identify specific patient factors that may affect outcomes. 29 patients with uncontrolled hypertension and renal artery FMD diagnosed by duplex ultrasound and angiography were prospectively enrolled. All patients underwent ...
de Raaf Michiel Alexander MA VU University Medical Center/Institute for Cardiovascular Research, Amsterdam, The - - 2014
The SU5416 combined with hypoxia (SuHx) rat model features angio-obliterative pulmonary hypertension resembling human pulmonary arterial hypertension. Despite increasing use of this model, a comprehensive haemodynamic characterisation in conscious rats has not been reported.We used telemetry to characterise haemodynamic responses in SuHx rats and associated these with serial histology.Right ventricular ...
Magder Sheldon A SA Department of Critical Care, McGill University Health Centre, Montreal, QC, - - 2014
Measurement of blood pressure is fundamental for the management of patients in shock, yet the physiological basis and meaning of blood pressure measurements are complex and often not well understood. This article is in two parts: part 1 deals with the mechanical and physiological aspects of blood pressure and its ...
Small Heather Yvonne HY Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, - - 2014
Novel antiangiogenic cancer therapies, particularly agents that block vascular endothelial growth factor (VEGF) signalling, have improved outcomes in patients with cancers and are now used as first-line therapies for some tumours. However, with VEGF inhibitors (VEGFIs) are new complications, particularly hypertension. VEGFI-induced hypertension is a dose-dependent phenomenon due to on-target ...
Neal Bruce B The George Institute for Global Health, University of Sydney, Royal Prince Alfred Hospital, Sydney, Australia. Electronic address: - - 2014
High blood pressure is the leading cause of premature mortality worldwide. Reducing salt intake lowers blood pressure and blood pressure-lowering reduces vascular disease. There is a very high likelihood that reducing dietary salt intake will prevent vascular disease and no evidence to suggest it will cause harm. With average population ...
Reeve Adam M - - 2014
Vascularized biological tissue has been shown to increase in stiffness with increased perfusion pressure. The interaction between blood in the vasculature and other tissue components can be modeled with a poroelastic, biphasic approach. The ability of this model to reproduce the pressure-driven stiffening behavior exhibited by some tissues depends on ...
Moulana Mohadetheh M Department of Psychiatry, University of Mississippi Medical Center, Jackson, - - 2014
The mechanisms responsible for the gender difference in blood pressure (BP) in humans are not clear. Over the past several years we have studied the spontaneously hypertensive rat (SHR) as a model of sex differences in BP control. In the present study, we tested the hypothesis that renal vascular and ...
Vinturache Angela E AE The Alberta Children's Hospital Research Institute for Child and Maternal Health, University of Calgary, Calgary, Alberta, Canada The Department of Physiology & Pharmacology, University of Calgary, Calgary, Alberta, - - 2014
This study aimed to elucidate the roles of both angiotensin II (ANG II) receptors - type 1 (AT1Rs) and type 2 (AT2Rs) - separately and together in influencing hemodynamic effects of endogenously produced nitric oxide (NO) during postnatal development. In conscious, chronically instrumented lambs aged ~1 week (8 ± 1 ...
Ormseth Michelle J MJ Division of Rheumatology, Department of Medicine, Vanderbilt University, Nashville, - - 2014
Objective: To examine the hypothesis that improving insulin sensitivity would improve vascular function in rheumatoid arthritis (RA). Methods: We performed a 20-week, single center, randomized, double-blind, placebo-controlled, cross-over study. Patients with RA (n=34) and moderate disease activity on stable disease modifying anti-rheumatic drug therapy were randomized to drug sequence, receiving ...
Durand Matthew J MJ Medical College of - - 2014
Increased intraluminal pressure can reduce endothelial function in resistance arteries; however the mechanism of this impairment is unknown. The purpose of this study was to determine the effect of local renin-angiotensin system inhibition on the pressure-induced blunting of endothelium-dependent vasodilation in human adipose arterioles. Arterioles (100-200 µm) were dissected from ...
Caligiuri Stephanie P B SP Canadian Centre for Agri-food Research in Health and Medicine, Institute of Cardiovascular Sciences, Asper Clinical Research Institute, St Boniface Hospital Research Centre, Winnipeg, Manitoba, Canada; and Departments of Physiology, Human Nutritional Sciences, and Internal Medicine, University of Manitoba, Winnipeg, Manitoba, - - 2014
In a randomized, double-blinded, controlled clinical trial, participants with peripheral arterial disease (75% hypertensive) consumed 30 g of milled flaxseed/d for 6 months. The flaxseed group exhibited significant reductions in systolic (-10 mm Hg) and diastolic (-7 mm Hg) blood pressure. Flaxseed contains the n3 fatty acid α-linolenic acid. Plasma ...
Triantafyllou Areti A 3rd Department of Internal Medicine, Papageorgiou Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. Electronic address: - - 2014
Early identification of hypertensive target organ damage (TOD) emerges as important for global cardiovascular risk assessment. Retinal vascular alterations, capillary rarefaction, and microalbuminuria represent different forms of microvascular TOD. However, data regarding their concomitant presence in the early stages of hypertension, the association of the number of affected organs with ...
Khoffi Foued F 2 European Research Group on Grafts Used in Vascular Surgery (ERGGVS), Faculty of Medicine, Strasbourg - - - 2014
Background: Compliance mismatch between native artery and a prosthetic graft used for infrainguinal bypass is said to be a factor for graft failure. The aim of this study was to develop a technique for measuring the compliance of collagen-coated polyethylene terephthalate (PET) vascular prostheses and to analyze the influence of ...
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