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Sindou Marc M Department of Neurosurgery, Hopital Neurologique Pierre Wertheimer, University Lyon 1, G.H.E, 59 Boulevard Pinel, Lyon, 69003, France, - - 2015
There are anatomical and physiological evidences that the ventrolateral (VL) region of the medulla plays an important role in blood pressure regulation and that dysfunction at this level may generate hypertension (HT). Vascular compression by a megadolicho-artery from the vertebrobasilar arterial system at the root entry/exit zone (REZ) of the ...
Davis Mark M Department of Medicine, Division of Cardiology, Jewish General Hospital, McGill University, 3755 Cote Ste-Catherine Rd, Suite E-215, Montreal, Quebec, H3T 1E2, - - 2014
Hypertension is common and leads to significant cardiovascular morbidity and mortality. Some patients are unable to achieve target blood pressures despite multiple antihypertensive medications; these patients are labeled as having resistant hypertension. To palliate the lack of pharmacologic options, recent technological advances led to the development of an interventional procedure ...
Lee Chong Guk CG Division of Pediatric Nephrology, Department of Pediatrics, Ilsan Paik Hospital, Inje University, 2280, Ilsanseo-gu, Goyang-si, Gyeonggi-do, 411-706, South Korea, - - 2014
Hypertension has become a serious global public health burden because of its high incidence and concomitant risk of cardiovascular disease. Many studies have verified that risk factors, such as hypertension and obesity which are responsible for cardiovascular disease, start in early childhood. In Asian countries, the prevalence of hypertension in ...
Kanwar Manreet M Cardiovascular Institute, Allegheny General Hospital, 320 East North Ave, 16th floor, South Tower, Pittsburgh, PA, 15212, USA, - - 2014
Heart failure with preserved ejection fraction (HFpEF) is a major cause of HF-related morbidity and mortality, with no medical therapy proven to modify the underlying disease process and result in improvements in survival. With long-standing pulmonary venous congestion, a majority of HFpEF patients develop pulmonary hypertension (PH). Elevated pulmonary pressures ...
Oktay A Afşin AA Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 N. St. Clair St., Suite 600, Chicago, IL, 60611, - - 2014
Hypertension is a major contributor to the development of heart failure with preserved ejection fraction (HFpEF). Our understanding of the epidemiology and pathophysiology of HFpEF in relation to hypertension has increased considerably in recent years. We now know that the pathophysiologic relationship between hypertension and HFpEF is more complex than ...
Fudim Marat M Vanderbilt University, Nashville, TN, - - 2014
Excess blood pressure remains the most important risk factor for cardiovascular and renal disease. Poly pharmacy has been proved safe and effective under clinical trial circumstances; however, the majority of patients fail to sustain pharmaceutical persistence and adherence. The opportunity to offer patients a treatment or device in addition or ...
Caligiuri Stephanie P B SP Canadian Centre for Agri-food Research in Health and Medicine (CCARM), St Boniface Hospital Research Centre, 351 Taché Avenue, Winnipeg, MB, Canada, R2H - - 2014
Hypertension is the single largest risk factor attributed to mortality in the world. Medications are the primary treatment for hypertension; however, adherence to drug regimens is low (~50 %). Low adherence may be a contributing factor leading to uncontrolled blood pressure in patients. An effective alternative or complement to medications in ...
Garnock-Jones Karly P KP Springer, Private Bag 65901, Mairangi Bay 0754, Auckland, New Zealand, - - 2014
Ripasudil hydrochloride hydrate (Glanatec® ophthalmic solution 0.4 %; hereafter referred to as ripasudil) is a small-molecule, Rho-associated kinase inhibitor developed by Kowa Company, Ltd. for the treatment of glaucoma and ocular hypertension. This compound, which was originally discovered by D. Western Therapeutics Institute, Inc., reduces intraocular pressure (IOP) by directly acting ...
Mir S S Ege University Faculty of Medicine, Department of Pediatric Nephrology, İzmir,Turkey - - - 2014
Primary hypertension in children is not a benign condition because of end--organ damage. Early investigations of cardiovascular effects rely on vascular structural and functional changes. We aimed to determine presence of early cardiovascular involvement in children with primary hypertension. For this purposes, we investigated functional and morphological changes in vascular ...
Wang Yan Y aShanghai Key Laboratory of Hypertension, Ruijin Hospital bResearch Center for Hypertension Management and Prevention in Community, Shanghai Institute of Hypertension, Shanghai Jiaotong University School of Medicine cXinzhuang Community Health Service Center, Shanghai, - - 2014
End-digit preference (EDP) of blood pressure (BP) has been reported in both general hospitals and primary clinics worldwide. We aimed to observe the longitudinal changes in EDP of BP recordings in hypertension patients and to estimate the impact of hypertension treatment target (140/90 mmHg) on the EDP of BP in Chinese ...
Lovshin Julie A JA Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, - - 2014
GLP-1 receptor (GLP-1R) agonists induce natriuresis and reduce blood pressure (BP) through incompletely understood mechanisms. We examined the effects of acute and 21-day administration of liraglutide on plasma atrial natriuretic peptide (ANP), urinary sodium excretion, office and 24-h BP, and heart rate (HR). Liraglutide or placebo was administered for 3 ...
Kolesnikova L I LI Research Center for Family Health and Human Reproduction Problems of Siberian Branch of Russian Academy of Medical Sciences, Irkutsk, - - 2014
Investigation of emotional sphere and LPO processes in adolescents of both sexes aged 14-17 years suffering from essential hypertension revealed pronounced changes in the emotional status associated with dysregulation in the LPO-antioxidant protection system. The emotional sphere in adolescents with hypertension was characterized by increased anxiety in combination with emotional ...
Lafont M M Departments of Endocrinology (M.L., M.H., A.T.), Anesthesiology (G.D.), Endocrine Surgery (T.W.) and Nuclear Medicine (J-B.C.), CHU Bordeaux and University of Bordeaux, France; Department of Endocrinology (C.F.), CHU Ft-de-France, - - 2014
Context: The per-operative hemodynamic behavior of normotensive incidentally discovered pheochromocytomas is poorly documented. Objective: To compare the per-operative hemodynamic instability and early post-operative outcome of normotensive pheochromocytomas, hypertensive pheochromocytomas, and benign non pheochromocytoma adrenal incidentalomas (AI). Design: Retrospective cohort treated in a single center. Patients and Methods: 50 patients (10 ...
Joshi Mark David - - 2014
Urbanisation has been described as a key driver of the evolving non-communicable disease (NCD) epidemic. In Africa, hypertension is the commonest cardiovascular problem. We determined the prevalence and risk factor correlates of hypertension in the largest Nairobi slum. In 2010 we conducted a population-based household survey in Kibera, a large ...
Sibony Patrick P Ophthalmology, SUNY Stony Brook, Health Sciences Center, Level 2 152, Stony Brook, New York, 11794, United States - - 2014
Purpose:To analyze the deformations of the peripapillary retinal pigment epithelial basement-membrane (ppRPE/BM)-layer in response to procedures that lower intracranial pressure(ICP). Second, to demonstrate how shape changes may complement the mean retinal nerve fiber layer(RNFL)-thickness as a measure of intracranial hypertension(ICH) and papilledema. Methods:We used Geometric Morphometrics on SD-OCT images to ...
Gaddum Nicholas R NR From the Division of Imaging Sciences and Biomedical Engineering, St. Thomas' Hospital, King's College London, London, United Kingdom (N.R.G., A. Gomez, T.S.); King's College London British Heart Foundation Centre, Department of Clinical Pharmacology, St Thomas' Hospital, London, United Kingdom (L.K., A. Guilcher, S.B., P.C.); and Department of Pediatric Cardiology and Pediatric Intensive Care Medicine, Hannover Medical School, Hannover, Germany - - 2014
Aortic pulse wave velocity (aPWV), a major prognostic indicator of cardiovascular events, may be augmented in hypertension as a result of the aorta being stretched by a higher distending blood pressure or by a structural change. We used a novel technique to modulate intrathoracic pressure and thus aortic transmural pressure ...
Friedberg Jennifer P JP From the Research and Development Service (J.P.F., M.A.R., M.E.W., I.L.) and Medical Service (S.N.), VA New York Harbor Healthcare System, NY; Departments of Medicine (J.P.F., S.N.) and Psychiatry (J.P.F.), New York University School of Medicine, NY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (J.W.-R.); Department of Health Education, Teachers College and the Mailman School of Public Health, Columbia University, New York, NY (J.P.A.); and Departments of Medicine and Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA - - 2014
Blood pressure (BP) control rates are suboptimal. We evaluated the effectiveness of 2 behavioral interventions to improve BP control via a 3-arm, randomized controlled trial of 533 adults with repeated uncontrolled BP, despite antihypertensive drug treatment for ≥6 months. The interventions were a tailored stage-matched intervention (SMI) or a nontailored ...
Patel Hitesh C HC From the National Institute of Health Research Cardiovascular Biomedical Research Unit, Department of Cardiology, Royal Brompton Hospital, London, United Kingdom (H.C.P., C.H., A.R.L., C.d.M.); Faculty of Medicine, National Heart and Lung Institute, Imperial College, London, United Kingdom (H.C.P., C.H., S.D.R., A.R.L., D.P.F., C.d.M.); Department of Outcomes Research, St. George's Vascular Institute, St George's University, London, United Kingdom (B.A.O.); Department of Cardiology, Ealing Hospital NHS Trust, Southall, London, United Kingdom (S.D.R.); and Monash Centre of Cardiovascular Research and Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia (H.K.). - - 2014
Early phase studies of novel interventions for hypertension, such as renal sympathetic denervation, are sometimes single-armed (uncontrolled). We explored the wisdom of this by quantifying the blood pressure fall in the placebo arms of contemporary trials of hypertension. We searched Medline up to June 2014 and identified blinded, randomized trials ...
Cuspidi Cesare C aDepartment of Health Science, University of Milano-Bicocca bResearch Institute Auxologico cDepartment of Clinical Sciences and Community Health, University of Milan and Policlinico Hospital Foundation dResearch Institute Multimedica, Sesto San Giovanni, Milan, Italy eUniversity Clinical Hospital Centre 'Dragisa Misovic', Belgrade, - - 2014
The association of white-coat hypertension (WCH) with target organ damage is still debated; in particular, the relationship of this blood pressure phenotype with subclinical vascular damage remains controversial. Thus, we carried out a systematic review and meta-analysis to provide updated information on carotid structural changes in WCH. Studies were identified ...
Yoon Sung Sug SS From the Division of Health and Nutrition Examination Surveys, National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD (S.S.Y., Q.G., T.N., V.B.); Epidemiology Branch, Program in Prevention and Population Sciences, Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.D.W.); and Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA (Y.H.). - - 2014
The aim of this study is to describe trends in the awareness, treatment, and control of hypertension; mean blood pressure; and the classification of blood pressure among US adults 2003 to 2012. Using data from the National Health and Nutrition Examination Survey 2003 to 2012, a total of 9255 adult ...
Xu Shancai S Department of Neurosurgery, First Affiliated Hospital of Harbin Medical University, No. 23 Youzheng Street, Nangang District, Harbin, 150001, Heilongjiang, - - 2014
Hyperperfusion syndrome (HPS) is a rare but potentially devastating postoperative complication developing after endarterectomy and carotid stenting. Limited information is available about this complication. The aim of this study was to assess the incidence of HPS and risk factors leading to its development. We retrospectively reviewed 178 consecutive cases of ...
Abreo Adrian P - - 2014
New information from various clinical settings suggests that tight blood pressure control may not reduce mortality and may be associated with more side effects. We performed cross-sectional multivariable ordered logistic regression to examine the association between predialysis blood pressure and the short physical performance battery (SPPB) in a cohort of ...
Hirschl Mirko M Department of Angiology, Hanuschkrankenhaus Vienna, Heinrich Collinstrasse 30, 1140, Vienna, Austria, - - 2014
Arterial baroreceptors are pressure sensors found in the carotid sinus near the bifurcation of the carotid artery and in the aortic arch. Carotid interventions, whether endovascular or surgical, affect this complicated control system and the post-interventional blood pressure behavior. Comparisons between the intervention techniques, however, are challenging due to the ...
Niiranen Teemu J TJ Population Studies Unit, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland; Department of Medicine, Turku University Hospital, Turku, - - 2014
Current guidelines make no outcome-based recommendations on the optimal measurement schedule for home blood pressure (BP). We enrolled 4,802 randomly recruited participants from three populations. The participants were classified by their (i) cross-classification according to office and home BP (normotension, masked hypertension, white-coat hypertension, and sustained hypertension) and (ii) home ...
Tocci Giuliano G Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome Sapienza, Sant'Andrea Hospital, Rome IRCCS Neuromed, Pozzilli (IS), - - 2014
Effective treatment of high blood pressure (BP) represents a key strategy for reducing the burden of hypertension-related cardiovascular and renal diseases. In spite of these well-established concepts, hypertension remains poorly controlled worldwide. In order to improve BP control in patients with hypertension, several interventions have been proposed, among which (1) ...
Coulson J M JM Wales Heart Research Institute, Cardiff University, Cardiff, - - 2014
It has been shown previously that changes in brainstem neural activity correlate with changes in both mean arterial pressure (MAP) and muscle sympathetic nerve activity (MSNA) during static handgrip (SHG). However, the relationship between baseline MAP and brainstem neural activity is unclear. We investigated changes in blood oxygen level-dependent (BOLD) ...
Akter Shamima S 1] Institute of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan [2] Health & Disease Research Center for Rural Peoples (HDRCRP), Mohammadpur, Dhaka, Bangladesh [3] National Center for Global Health and Medicine (NCGM), Toyama, Shinjuku-ku, Tokyo, - - 2014
Endothelin-1 (ET-1) is a potential marker of the endothelial dysfunction, which has been shown to be elevated in hypertensive subjects. No previous study has investigated the circulatory level of ET-1 and hypertension in a South Asian country. The present study assessed the circulating levels of ET-1 in subjects with or ...
Ventura Nicole M NM Department of Biomedical and Molecular Sciences, Queen's University, Rm 850 Botterell Hall 18 Stuart St., Kingston, ON, K7L 3N6, Canada, - - 2014
Investigations regarding hypertension and dietary sodium, both factors that influence stroke risk, have previously been limited to using genetically disparate treatment and control groups, namely the stroke-prone, spontaneously hypertensive rat and Wistar-Kyoto rat. In this investigation, we have characterized and compared cerebral vasoactive system adaptations following stroke in genetically identical, ...
Hu S S Irvine3 circulation vascular labs & san val. epidemiology, dept biomedical sciences, chieti-pescara university pescara, italy - - - 2014
This registry study aimed to evaluate supplementation with Pycnogenol on altered endothelial function (EF) in borderline hypertensive, hyperlipidemic and hyperglycemic subjects without atherosclerotic changes in their main arteries and no coronary artery disease. Flow mediated dilatation and endothelium-independent dilatation were measured with brachial ultrasound after occlusion. Also, after occlusion, laser ...
Ahn Seong Joon SJ Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea (South), Republic - - 2014
Purpose: To investigate retinal and choroidal changes using spectral-domain optical coherence tomography (SD-OCT) and to evaluate visual outcome in patients with severe hypertension. Methods: In forty-two eyes with hypertensive retinopathy from 21 patients with severe hypertension (systolic blood pressure [SBP]>180 mmHg or diastolic BP [DBP]>110 mmHg), SD-OCT was performed on ...
Manios Efstathios E aDepartment of Clinical Therapeutics, Medical School of Athens, Alexandra Hospital, Athens, Greece bDepartment of Cardiology, Goethe University Frankfurt, Frankfurt am Main, - - 2014
The masking effect (ME) is present in masked hypertensive patients; however, both normotensive and hypertensive individuals may show a similar phenomenon. Previous studies have shown that ME has been associated with left ventricular hypertrophy and microalbuminuria in treated hypertensive patients. The aim of our study was to evaluate the association ...
Martin Una U Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, UK; - - 2014
This study investigated the relationship of ethnicity to the differences between blood pressure (BP) measured in a clinic setting and by ambulatory blood pressure monitoring (ABPM) in individuals with a previous diagnosis of hypertension (HT) and without a previous diagnosis of hypertension (NHT). A cross-sectional comparison of BP measurement was ...
Celık Turgay T Department of Cardiology, Gulhane Medical Academy , Ankara , - - 2014
Vascular inflammation plays an important role in the pathophysiology of hypertension and high levels of endocan may reflect ongoing vascular inflammation in hypertensive patients. In the present hypothesis-generating study, we aimed at investigating the comparative effects of amlodipine and valsartan on endocan levels in newly diagnosed hypertensive patients. The study ...
Ataklte Feven F From the Department of Medicine, Kings College London, London, UK (F.A.); Department of Medicine, Weill Cornell Medical College, New York, NY (S.E.); Veteran Affairs Pittsburgh Health Care System, PA (S.E.); Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK (S.K.); Department of Medicine, Jamaica Medical Center, New York, NY (B.T.); Hubert Department of Public Health, Rollins School of Public Health, Emory University, Atlanta, GA (J.B.E.-T.); MedStar Health, Baltimore, MD (J.B.E.-T.); South African Medical Research Council and University of Cape Town, Cape Town, South Africa (A.P.K.); The George Institute for Global Health, Sydney, Australia (A.P.K.); and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands - - 2014
The burden of hypertension in Sub-Saharan Africa has been increasing over the past few decades. However, a large proportion of the population with hypertension remains undiagnosed, untreated, or inadequately treated, contributing to the rising burden of cardiovascular disease in the region. We conducted a systematic review and meta-analysis to assess ...
Krmar Rafael T RT Karolinska Institutet, Department for Clinical Science, Intervention and Technology, Division of Pediatrics, Karolinska University Hospital, Huddinge, - - 2014
Casual blood pressure (CBP) is considered a reliable proxy for cardiovascular health. Although the auscultatory technique is the reference standard method for measuring CBP, oscillometric devices are increasingly being used in children. We sought to establish oscillometric CBP normative standards for Swedish children. Cross-sectional oscillometric CBP readings were obtained by ...
Eirin Alfonso A Division of Nephrology and Hypertension, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, - - 2014
Hypertension remains an important modifiable risk factor for cardiovascular disease, associated with increased morbidity and mortality. Deciphering the mechanisms involved in the pathogenesis of hypertension is critical, as its prevalence continues increasing worldwide. Mitochondria, the primary cellular energy producers, are numerous in parenchymal cells of the heart, kidney, and brain, ...
Nagahama Kazufumi K Department of Cardiovascular Medicine, Nephrology and Neurology, Graduate School of Medicine, University of the Ryukyus, Okinawa, - - 2014
The purpose of this study was to examine the associations between serum uric acid (SUA) levels and the incidences of hypertension and metabolic syndrome (MetS) in a large screened cohort of Japanese men and women. We evaluated 4812 subjects (males, 2528; females, 2284; mean age, 47.5 years) who underwent health ...
Johnson Heather M HM Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA, - - 2014
Only 38 % of young adults with hypertension have controlled blood pressure. Lifestyle education is a critical initial step for hypertension control. Previous studies have not assessed the type and frequency of lifestyle education in young adults with incident hypertension. The purpose of this study was to determine patient, provider, and ...
Rahman Md Mizanur MM aDepartment of Global Health Policy, The University of Tokyo, Tokyo, Japan bDepartment of Population Science and Human Resource Development, University of Rajshahi, Rajshahi, Bangladesh cDepartment of Epidemiology and Prevention, Clinical Research Center, National Center for Global Health and Medicine, Tokyo, - - 2014
We investigated the prevalence, awareness, treatment, and control of hypertension and associated risk factors in the Bangladeshi adult population. The data for this study were extracted from the nationally-representative 2011 Bangladesh Demographic and Health Survey. Socio-demographic profiles, height, weight, blood pressure measurements, and management were recorded from 7876 adults aged ...
Cuspidi Cesare C aDepartment of Health Science, University of Milano-Bicocca bIstituto Auxologico Italiano cDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy dFondazione, Policlinico di Milano University Clinical Hspital Centre 'Dragisa Misovic', Belgrade, Serbia eIstituto di Ricerche a Carattere Scientifico Multimedica, Sesto San Giovanni, Milan, - - 2014
AIM:: The clinical and prognostic relevance of white-coat hypertension (WCH) has not been fully elucidated; in particular, the association of this blood pressure phenotype with suclinical organ damage remains unclear. We performed a systematic meta-analysis in order to provide a comprehensive information on cardiac structural and functional changes in WCH, ...
Dornas Waleska C WC aResearch in Biological Sciences - NUPEB, Federal University of Ouro Preto bDepartment of Statistics, Institute of Exact and Biological Sciences, Federal University of Ouro Preto cDepartment of Biological Sciences, Institute of Exact and Biological Sciences, Federal University of Ouro Preto dDepartment of Foods, School of Nutrition, Federal University of Ouro Preto, Ouro Preto, Minas Gerais, - - 2014
Considering the growing body of evidence that indicates the contribution of superoxide anions (O2) and other reactive oxygen species (ROS) to the development of hypertension, we assessed whether animal models of hypertension have a benefic effect with tempol, a superoxide dismutase mimetic, to help augment the design of future studies. ...
Chang Ta-Yuan TY aDepartment of Occupational Safety and Health, College of Public Health, China Medical University bDepartment of Family Medicine, China Medical University Hospital cSchool of Medicine, College of Medicine, China Medical University dDepartment of Pharmacy, College of Pharmacy, China Medical University, Taichung eInstitute of Labor, Occupational Safety and Health, Ministry of Labor, Executive Yuan, Taipei, Taiwan, - - 2014
Noise exposure is associated with elevated blood pressure, but the effects on susceptible workers have not been reported. This repeated-measure study investigated the effects of noise exposure on 24-h ambulatory blood pressure among hypertensive, pre-hypertensive, and normotensive adults. We enrolled 113 volunteers in an occupational cohort in 2009. Individual noise ...
Kumagai Kyoko K aDepartment of Ophthalmology and Visual Sciences bCenter for Genomic Medicine, Kyoto University Graduate School of Medicine cDepartment of Health Informatics dDepartment of Medical Ethics and Medical Genetics, Kyoto University School of Public Health eKyoto University Medical Research Support Center, Kyoto, - - 2014
Although central blood pressure (BP) is considered to be more closely associated with large arterial remodeling and cardiovascular outcomes than brachial BP, few studies have investigated these associations with changes in small arteries. As morphological changes in retinal vessels might be associated with cardiovascular outcomes, we conducted a cross-sectional study ...
Adeloye Davies D aCentre for Population Health Sciences and the World Health Organization's Collaboration Centre for Population Health Research and Training, University of Edinburgh Medical School, Edinburgh bSchool of Biosciences, University of Kent, Canterbury, Kent cNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Nuffield Orthopaedic Centre, Oxford, UK dHealth Reform Foundation of Nigeria, HERFON Secretariat, Asokoro, Abuja, Federal Capital Territory, - - 2014
Hypertension is a leading cause of morbidity and mortality in Africa, and Nigeria, the most populous country in the continent, hugely contributes to this burden. To provide an improved estimate of the prevalence and number of cases of hypertension in Nigeria based on the cut-off 'at least 140/90 mmHg', towards ensuring ...
Spronck Bart B aDepartment of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University Medical Centre, Maastricht, The Netherlands bDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands cDepartments of Internal Medicine dRadiology, Maastricht University Medical Centre, Maastricht, The - - 2014
Arterial stiffness measures such as pulse wave velocity (PWV) have a known dependence on actual blood pressure, requiring consideration in cardiovascular risk assessment and management. Given the impact of ageing on arterial wall structure, the pressure-dependence of PWV may vary with age. Using a noninvasive model-based approach, combining carotid artery ...
Mancia Giuseppe G aUniversity of Milano-Bicocca, Centro Interuniversitario di Fisiologia Clinica e Ipertensione, Istituto Auxologico Italiano IRCCS, Milan, Italy bFoundation Medical Research Institutes, Paris, France cInstituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil dCHU Avicenne, Unité Médecine Interne-Hypertension Artérielle, Bobigny, France eUniversity of Pisa/School of Medicine, Pisa, Italy fInstituto de Corazón de Querétaro, Querétaro, Mexico gMinistry of Health of the Russian Federation, Cardiology Research Complex, Moscow, Russia hServicio de Medicina Interna, Unidad Metabólico-Vascular, Hospital Universitario La Paz, IdiPaz, Madrid, - - 2014
An international double-blind, parallel-group, randomized controlled trial was performed to determine the efficacy and safety of a new first-line strategy in mild to moderate hypertension based on a single-pill combination of perindopril/amlodipine versus a validated stepped-care strategy (initiation with valsartan monotherapy, up-titrating to valsartan/amlodipine after 2 months). At inclusion, patients ...
Henry Thea L TL Bresmed Health Solutions, North Church House, Sheffield, S1 2DW, United - - 2014
Abstract Objectives Safety and efficacy data for catheter-based renal denervation (RDN) in the treatment of resistant hypertension have been used to estimate the cost effectiveness of this approach. However, there are no Dutch-specific analyses. We examined the cost effectiveness of RDN from the perspective of the healthcare payer in The ...
He Zheng Z Dept of Optometry & Vision Sciences, The University of Melbourne, Level 1, Kenneth Myer Building, 30 Royal Parade, Parkville, Melbourne, Victoria, 3010, - - 2014
Purpose: to consider the effect of chronic arterial hypertension on the susceptibility of the retina to acute intraocular (IOP) challenge. Methods: Anesthetized adult Long-Evans rats with normal (n=5, receiving saline subcutaneously), chronic high blood pressure (BP) for 4 weeks (n=15, Angiotensin II subcutaneously) and acute high BP for 1 hour ...
Muntner Paul P Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; - - 2014
Several ambulatory blood pressure monitoring (ABPM) measures have been associated with increased cardiovascular disease risk independent of clinic blood pressure (BP). African Americans have higher clinic BP compared with Whites but few data are available on racial differences in ABPM measures. We compared ABPM measures between African American (n = ...
Suzuki Hiromichi H Department of Nephrology, Saitama Medical University 38 Morohonngo, Moroyama machi, Iruma gun, Saitama, 350-0495, Japan - - 2014
The guidelines for hypertension require the presence of compelling indications for pharmacological management of hypertension associated with various diseases. Data mainly obtained through randomized controlled trials have provided evidence supporting effectiveness of the combination of losartan (Lo) and hydrochlorothiazide (HCTZ) for management of hypertensive patients. However, there have been few ...
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