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Sancini A A Departments of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine. "Sapienza" University of Rome, - - 2014
Everyday outdoor workers are exposed to chemicals including the polycyclic aromatic hydrocarbons (PAHs). The aim of the study is to evaluate the relationship between hydroxypyrene and blood pressure in outdoor workers. 374 subjects of both sexes entered the study. We evaluated the assay of urinary hydroxypyrene (1-HOP); their blood pressure ...
Dağ Sevin S Department of Physical Medicine and Rehabilitation, Diyarbakir Training and Research Hospital, Diyarbakir, - - 2014
<p>Objectives: The heart is a commonly involved organ in systemic sclerosis (SSc) and pulmonary hypertension is a commonly observed complication that is associated with poor prognosis in this disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthases. In this study, we aimed to contribute to an early ...
Hakim Ashrafalsadat A Chronic Disease Care Research Center, Department of Nursing, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, - - 2014
The underlying cause of high blood pressure in adulthood is rooted in childhood. The evidence points to higher prevalence of hypertension among children in recent years. This study aims to investigate the prevalence of high blood pressure among Ahvaz children, as a sample of Iranian kids, and compare it with ...
Saneei P P Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, - - 2014
Findings were not consistent on the therapeutic effect of Dietary Approaches to Stop Hypertension (DASH) diet on blood pressure. We aimed to review systematically and perform a meta-analysis to assess the magnitude of the effect of the DASH diet on blood pressure in randomized controlled trials (RCTs) among adults. We ...
Fujisaki Kiichiro K Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
It is unknown whether the use of diuretics is optimal over other antihypertensive agents in patients with chronic kidney disease (CKD) whose blood pressure remains uncontrolled despite treatment with renin-angiotensin system (RAS) inhibitors. In this study, we assessed the additive effects of hydrochlorothiazide (HCTZ) on reducing proteinuria in CKD patients ...
Odili Augustine N AN Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, University of Abuja, Abuja, Nigeria. ; Studies Coordinating Centre, Division of Hypertension and Cardiovascular Rehabilitation, Department of Cardiovascular Diseases, University of Leuven, Leuven, - - 2014
Sub-Saharan Africa is currently undergoing an epidemiological transition from a disease burden largely attributable to communicable diseases to that resulting from a combination of both communicable and chronic non-communicable diseases. Data on chronic disease incidence, lifestyle, environmental and genetic risk factors are sparse in this region. This report aimed at ...
Sumbria Minakshi M Senior Resident, Department of Pharmacology, IGMC, Shimla, India. Electronic address: - - 2014
Hypertension is often complicated by increased arterial stiffness and is an independent predictor of adverse cardiovascular (CV) outcome. Beta blockers and angiotensin receptor blockers (ARBs) are commonly used antihypertensive agents. The effect of beta blockers and ARBs on arterial stiffness has not been compared adequately. The aim of the present ...
Vinereanu Dragos D University of Medicine and Pharmacy Carol Davila, Bucharest, Romania. Electronic address: - - 2014
The objective of this study is to compare the effects of 2 types of diuretics, indapamide and hydrochlorothiazide, added to an angiotensin-converting enzyme inhibitor, on ventricular and arterial functions in patients with hypertension and diabetes. This is a prospective, randomized, active-controlled, PROBE design study in 56 patients (57 ± 9 ...
Gossell-Williams M M Department of Basic Medical Sciences, Pharmacology Section, The University of the West Indies, Kingston 7, Jamaica. - - 2014
The second Jamaica Health and Lifestyle Survey completed in 2007-2008 provided evidence that the prevalence of hypertension has increased significantly since 2000-2001. With more of the population living with hypertension, greater will be the need to ensure the best quality of life. A recent survey conducted in the ambulatory section ...
Shantakumari Nisha N Asst. Professor, Department of Physiology, Gulf Medical University, Ajman, P.O. Box: 4184, United Arab Emirates. Electronic address: - - 2014
Hypertension affects more than a quarter of the global adult population. Studies conducted worldwide suggest an overall small, yet useful, role of omega-3 PUFAs in reducing blood pressure in hypertensive patients. However there is no substantial data in this regard from population based in Middle East and Asia. To determine ...
Sanghavi Sarah S Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, N.Y., - - 2014
Despite the availability of blood pressure (BP)-lowering medications and dietary education, hypertension is still poorly controlled in the chronic kidney disease (CKD) population. As glomerular filtration rate declines, the number of medications required to achieve BP targets increases, which may lead to reduced patient adherence and therapeutic inertia by the ...
Taheri Ladan L Department of Cardiology, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan, - - 2014
Lead is a pollutant with numerous adverse effects on health. Since it can affect blood pressure, peripheral blood vessels, and the heart, the present study aimed to evaluate the relation between occupational exposure to lead and blood pressure. This cross-sectional study included male individuals working in battery firms in Isfahan. ...
Verma Vipin V Maulana Azad Medical College, New Delhi, - - 2014
Hepatic venous pressure gradient (HVPG) is a prognostic marker in cirrhosis, but is invasive. There is a need to validate a noninvasive marker to measure portal hypertension. Aspartate aminotransferase/platelet ratio index (APRI) is proposed as a good noninvasive estimator of hepatic fibrosis. Whether APRI could be used as noninvasive tool ...
Mirhafez Seyed Reza SR Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Student Research Committee, Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, - - 2014
Hypertension is an important risk factor for cardiovascular disease and there is increasing evidence that inflammation and abnormal immune responses are involved in the pathogenesis of hypertension. However, the data on the association between specific cytokine concentrations and hypertension are inconsistent. We have evaluated the association between 12 cytokines/growth factors ...
Zhang Jun J Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Southern Medical University, Nanjing, - - 2014
Resistant hypertension indicates that the blood pressure cannot reach the target value despite standard drug treatment, which harbors an increased risk for cardiovascular diseases. The role of the carotid sinus in regulating blood pressure has long been observed; thereby, the idea that treating resistant hypertension by stimulating carotid baroreceptors emerged. ...
Mas-Heredia Minerva M Centro de Salud Les Corts, Consorci d'Atenció Primària de Salut Eixample (CAPSE), Barcelona, - - 2014
Blood pressure measurement methods and conditions are determinants of hypertension diagnosis. A recent British guideline recommends systematic 24-h ambulatory blood pressure monitoring. However, these devices are not available at all health centers and they can only be used by 1 patient per day. The aim of this study was to ...
Kovács Katalin Réka KR Department of Neurology, Clinical Center, University of Debrecen, Debrecen, Hungary. Electronic address: - - 2014
Hypertension and dyslipidemia belong to the most prevalent modifiable risk factors for cerebrovascular and cardiovascular diseases. Hereby, we aimed to examine the combined effects of newly diagnosed hypertension and hyperlipidemia on the characteristics of the arterial wall and on cognitive function. We examined 72 hypertensive and 85 apparently healthy individuals. ...
Ulu Sena Memnune SM Department of Internal Medicine, Faculty of Medicine, Afyon Kocatepe University; Afyonkarahisar-Turkey. - - 2014
The lack of nocturnal decline in blood pressure (BP) is associated with an increase in cardiovascular events. Restless leg syndrome (RLS) is an uncomfortable feeling in which the patient wants to budge the legs with ache in the legs. RLS also increases the hypertension and cardiovascular risk. In this study, ...
Her Ae Young AY Division of Cardiology, Department of Internal Medicine, School of Medicine, Kangwon National University; Chuncheon-Republic of Korea. - - 2014
Home blood pressure (HBP) measurements are known as an important adjunct to office blood pressure (OBP) measurements in clinical practice. But little is known about the relationship between HBP and subclinical target organ damage (TOD) other than left ventricular hypertrophy (LVH). So we investigated the relationship of HBP measurements with ...
Uçar Hakan H Clinic of Cardiology, Adana Numune Training and Research Hospital; Adana-Turkey. - - 2014
Morning blood pressure surge (MBPS) is an independent predictor of atherothrombotic cardiovascular events in hypertensive patients. There is evidence from studies supporting the validity of mean platelet volume (MPV) as a marker of vascular risk and predictor of thrombotic complications. The aim of this study is to investigate the relationship ...
Bond Vernon V Department of Health, Human Performance and Leisure Studies, and the Cancer Center Physical Medicine and Nutrition Laboratory, Howard University, Washington, DC 20059, - - 2014
Previous studies have shown that beetroot juice (BJ) decreases systolic blood pressure (SBP) and oxygen demand. This study tests the hypothesis that a beetroot juice (BJ) treatment increases heart rate variability (HRV) measured by the average standard deviation of normal-normal electrocardiogram RR intervals (SDNN) and the low frequency (LF), mainly ...
Zhou Lihong L Department of Human Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, Hunan Province, - - 2014
Various retinal injuries induced by ocular hypertension have been shown to induce plastic changes in retinal synapses, but the potential regulatory mechanism of synaptic plasticity after retinal injury was still unclear. A rat model of acute ocular hypertension was established by injecting saline intravitreally for an hour, and elevating the ...
Bueche Celine Z CZ Department of Neurology, Otto-von-Guericke University Magdeburg, Germany ; German Center for Neurodegenerative Diseases (DZNE) Magdeburg, - - 2014
There is substantial controversy regarding the causative role of amyloid β (Aβ) deposition in Alzheimer's disease (AD). The cerebrovasculature plays an important role in the elimination of Aβ from the brain and hypertension is a well-known risk factor for AD. In spontaneously hypertensive stroke-prone rats (SHRSP), an animal model of ...
Greiner Sebastian S Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany (S.G., A.J., M.A., A.H., T.H., S.H., H.A.K., - - 2014
Pulmonary artery pressure (PAP) is an important marker in cardiovascular disorders, being closely associated with morbidity and mortality. Noninvasive assessment by Doppler echocardiography is recommended by current guidelines. So far, the reliability of this method has been assessed only in small studies with contradictory results. Therefore, the aim of this ...
Eccher Claudio C Fondazione Bruno Kessler, Trento, - - 2014
In the last years, there has been a growing interest in health mobile applications. Great benefits could be gained by seemingly "simple" solutions if these were designed to build a bridge between doctors and patients. In this paper, we describe a mobile health solution for patients allowing them to measure ...
Ghamami Niousha N Biology and Pharmacology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada, L8S - - 2014
Calcium channel blockers are a heterogeneous class of drugs, including dihydropyridine and non-dihydropyridine subgroups, commonly used in the treatment of hypertension. A systematic review of the 24-hour time course of the blood pressure-lowering effect has not been published. To assess how much variation there is in hourly systolic and diastolic ...
Barrios Vivencio V Department of Cardiology, Hospital Ramon y Cajal, - - 2014
Combined therapy is required in the majority of patients with hypertension to achieve blood pressure (BP) targets. Although different antihypertensive drugs can be combined, not all combinations are equally effective and safe. In this context, the combination of a renin angiotensin system inhibitor with a diuretic, usually a thiazide, particularly ...
Kadoya Manabu M Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Hyogo College of Medicine, Nishinomiya, Hyogo, - - 2014
Basic studies have shown that brain-derived neurotrophic factor (BDNF) has critical roles in the survival, growth, maintenance, and death of central and peripheral neurons, while it is also involved in regulation of the autonomic nervous system. Furthermore, recent clinical studies have suggested potential role of plasma BDNF in the circulatory ...
Hür Ender E Division of Nephrology, Bülent Ecevit University, Zonguldak, - - 2014
Objectives. Hypertension and hypervolemia relationship was proven among renal disease, although it is not known in normal population. Present study determines the fluid distribution defects in relation to blood pressure. Material and Methods. In a population-based survey in Turkey demographics, height, weight, blood pressure, urine analysis, and serum creatinine measurements ...
El Bcheraoui Charbel C Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Avenue, Suite 600, Seattle, WA 98121, - - 2014
Current data on hypertension in the Kingdom of Saudi Arabia are lacking. We conducted a national survey to inform decision-makers on the current magnitude of the epidemic. We measured systolic and diastolic blood pressure of 10,735 Saudis aged 15 years or older and interviewed them through a national multistage survey. ...
Santi Xavier Patrícia P Botucatu School of Medicine, São Paulo State University, São Paulo, - - 2014
Volume overload is the main factor responsible for the pathogenesis of hypertension in dialysis patients. Few studies have evaluated the interpretation of the parameters obtained by bioelectrical impedance (BIA) to manage these patients. The aim of this study was to assess the best cutoff level of volume overload obtained by ...
Afridi Hassan Imran - - 2014
The abnormal metabolism of metal ions plays an important role in health and disease conditions, and studies about them have been attracting significant interest. The aim of our study was to assess the toxic elements arsenic (As), cadmium (Cd), nickel (Ni), and lead (Pb) in biological samples (scalp hair, blood, ...
Hatori Nobuo N Kanagawa Physicians - - 2014
We performed cross-sectional surveys to investigate changes in clinical practices regarding blood-pressure control in patients with hypertension from 2008 through 2011. Questionnaires regarding the care of patients with hypertension were mailed to members of the Kanagawa Physicians Association in Kanagawa Prefecture, Japan. Data were obtained on 675 patients in 2008, ...
Zhu Pengli P Department of Geriatric Medicine, Fujian Provincial Hospital, Fujian Provincial Institute of Clinical Geriatrics, Fujian Medical University, Fuzhou, - - 2014
This study aimed to investigate the correlation between quantitative retinal vascular parameters such as central retinal arteriolar equivalent (CRAE) and retinal vascular fractal dimension (D(f)), and cardiovascular risk factors in the Chinese Han population residing in the in islands of southeast China. In this cross-sectional study, fundus photographs were collected ...
Ma Heather Ting HT Department of Electronic and Information Engineering, Harbin Institute of Technology Shenzhen Graduate School, Shenzhen 518055, - - 2014
Blood pressure is one important risk factor for stroke prognosis. Therefore, continuous monitoring of blood pressure is crucial for preventing and predicting stroke. However, current blood pressure devices are mainly air-cuff based, which only can provide measurements intermittently. This study proposed a new blood pressure estimation method based on the ...
Hu Shuai-Shuai SS Institute of Microcirculation, Peking Union Medical College & Chinese Academy of Medical Sciences Beijing, China ; Key Lab. of Microcirculation, National Health and Family Planning Commission - - 2014
The study aims to find a new biomarker in hypertension. Our study is the first time to demonstrate that the CD62P small microparticle (diameter is <0.5 um) was a new microparticle population and a new biomarker in hypertension.
Mizuno Tomohiro T Department of Analytical Pharmacology, Faculty of Pharmacy, Meijo University, Nagoya, - - 2014
Blood pressure (BP) telemonitoring systems and pharmacist management programs were introduced into Haruka Community Pharmacy. A 22-year-old healthy male came to the community pharmacy, although he was not in a diseased state, he had been informed previously that he had a moderately high BP during a routine examination. He continued ...
Magdás Annamária A County Clinical Hospital-Internal Medicine Department IV, University of Medicine and Pharmacy Tîrgu Mures, Str. Gh. Marinescu Nr. 38, 540139 Tîrgu Mures, - - 2014
Hypertension in the elderly is characterized by isolated systolic hypertension and high variability, but its clinical significance is not yet fully understood. The goal of this paper was to assess circadian blood pressure variability (BPV) in elderly hypertensives, and to determine its relationship to cardiovascular risk factors. To achieve this ...
Herrera Victoria L VL Whitaker Cardiovascular Institute, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of - - 2014
Multiple clinical studies show that arterial stiffness, measured as pulse wave velocity (PWV), precedes hypertension and is an independent predictor of hypertension end organ diseases including stroke, cardiovascular disease and chronic kidney disease. Risk factor studies for arterial stiffness implicate age, hypertension and sodium. However, causal mechanisms linking risk factor ...
Chung Chang-Min CM School of Traditional Chinese Medicine, College of Medicine, Chang Gung University, Chiayi, Taiwan ; Division of Cardiology, Chang Gung Memorial Hospital, Chiayi, - - 2014
Resistant hypertension (RH) is a common clinical condition associated with increased cardiovascular mortality and morbidity in older patients. Several factors and conditions interfering with blood pressure (BP) control, such as excess sodium intake, obesity, diabetes, older age, kidney disease, and certain identifiable causes of hypertension are common in patients resistant ...
Saberi Isfeedvajani Mohsen M 1. Assistant Professor, Medicine, Quran and Hadith Research Center and Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran. - - 2014
Background Hypertension is a risk factor for life threatening diseases such as cerebrovascular accidents, coronary artery diseases, congestive heart failure and chronic renal failure. The prevalence of non-communicable diseases such as hypertension and diabetes including obesity has increased over the past few years in Iran. The first step for modification ...
Lonjaret Laurent L Department of Anesthesiology and Intensive Care, Clinique des eaux claires, Baie-Mahault, - - 2014
Perioperative blood pressure management is a key factor of patient care for anesthetists, as perioperative hemodynamic instability is associated with cardiovascular complications. Hypertension is an independent predictive factor of cardiac adverse events in noncardiac surgery. Intraoperative hypotension is one of the most encountered factors associated with death related to anesthesia. ...
Pechanova Olga O Institute of Normal and Pathological Physiology and Centre of Excellence for Nitric Oxide Research, Slovak Academy of Sciences, Bratislava 81371, Slovak Republic. - - 2014
The pineal hormone, melatonin (N-acetyl-5-methoxytryptamine), shows potent receptor-dependent and -independent actions, which participate in blood pressure regulation. The antihypertensive effect of melatonin was demonstrated in experimental and clinical hypertension. Receptor-dependent effects are mediated predominantly through MT1 and MT2 G-protein coupled receptors. The pleiotropic receptor-independent effects of melatonin with a possible ...
Ghadhanfar Elham E Department of Physiology, Faculty of Medicine, Kuwait University, Kuwait City, - - 2014
Ouabain is a cardiac glycoside produced in the adrenal glands and hypothalamus. It affects the function of all cells by binding to Na+/K+-ATPase. Several lines of evidence suggest that endogenous ouabain could be involved in the pathogenesis of essential (particularly, salt-sensitive) hypertension. However, information regarding the postulated hypertensive effect of ...
Khan Abdul Hye AH Department of Pharmacology and Toxicology, Medical College of Wisconsin Milwaukee, WI, - - 2014
Epoxyeicosatrienoic acids (EETs) contribute to blood pressure regulation leading to the concept that EETs can be therapeutically targeted for hypertension and the associated end organ damage. In the present study, we investigated anti-hypertensive and kidney protective actions of an EET analog, EET-B in angiotensin II (ANG II)-induced hypertension. EET-B was ...
Wang Yixuan Y Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, Chaoyang District, Beijing, - - 2014
Homocysteine (Hcy) is regarded as a risk factor for hypertension, but research on the causal relationship between Hcy and hypertension is limited. In the present study, we prospectively tracked the blood pressure progression of a normotensive population with different Hcy levels over a 2-year period. The incidence of hypertension with ...
Støy Julie J Department of Internal Medicine and Endocrinology, Aarhus University Hospital, Aarhus, - - 2014
The genetics of hypertension has been scrutinized in large-scale genome-wide association studies (GWAS) with a large number of common genetic variants identified, each exerting subtle effects on disease susceptibility. An amino acid polymorphism, p.Arg82Cys, in CD300LG was recently found to be associated with fasting HDL-cholesterol and triglyceride levels. The polymorphism ...
Malaty John J Department of Community Health and Family Medicine, University of Florida, Gainesville, Florida, - - 2014
A 46-year-old African-American man with a history of hypertension, end-stage kidney disease (on haemodialysis) and previous cocaine misuse presented to the emergency room with a sudden onset of severe headache and diaphoresis without other neurological or cardiovascular signs/symptoms. He checked his blood pressure at home and found it to be ...
Yang Lei L Department of Cardiothoracic Surgery, Nanjing Children's Hospital Affiliated of Nanjing Medical University Jiangsu Province, - - 2014
Pulmonary arterial hypertension (PAH) leads to pressure overload in the right ventricle (RV) and induces right ventricular hypertrophy (RVH). GPR91 is an orphan G-protein-coupled receptor (GPCR) that has been characterized as a receptor for succinate, which increases in RVH; however, its role remains unknown. We studied succinate-GPR91 signaling in a ...
Kıvrak Yüksel Y Department of Psychiatry, Kafkas University School of Medicine, 36000 Kars, - - 2014
Venlafaxine is the first antidepressant that acts via inhibiting serotonin and noradrenaline reuptake. Hypertension is observed in doses exceeding 300 mg/day and is the most feared complication. We report a patient with accelerated hypertension after venlafaxine use observed at a dose of 150 mg/day. A 23-year-old patient with symptoms of insomnia, depression, ...
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