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Páll Dénes D Department of Medicine, Clinical Center, University of Debrecen, Nagyerdei krt 98 Pf 19, 4032, Debrecen, Hungary, - - 2014
The blood pressure (BP) of most patients on antihypertensive monotherapy or bitherapy remains uncontrolled. Our study evaluated the efficacy of triple therapy with perindopril, amlodipine, and indapamide sustained release (SR) in patients with uncontrolled hypertension on previous antihypertensive therapy. This 4-month, multicenter, prospective, observational, open-label study included patients switched from ...
Holló Gábor G Department of Ophthalmology, Semmelweis University, Budapest, Hungary, - - 2014
A new preservative-free fixed-dose combination of 0.0015% tafluprost, a prostaglandin F2α analog, and 0.5% timolol (TAF/TIM; Santen Oy, Tampere, Finland), a beta-adrenergic antagonist has recently been developed. The intraocular pressure (IOP) reduction with TAF/TIM in open-angle glaucoma and ocular hypertension is similar to that of other prostaglandin-timolol fixed-combination products. Patients ...
Austin Christopher - - 2014
Background:Elevated mean right atrial pressure (RAP) measured by cardiac catheterization is an independent risk factor for mortality. Prior studies have demonstrated a modest correlation with invasive and noninvasive echocardiographic right atrial pressure (eRAP), but the prognostic impact of eRAP has not been previously evaluated in pulmonary arterial hypertension (PAH) patients. ...
Hyman D J DJ Section of General Internal Medicine, Department of Family and Community Medicine, Baylor College of Medicine, Houston, TX, - - 2014
Non-adherence has been a major concern in the treatment of hypertension and is particularly important in understanding and intervening in patients who appear to have resistant hypertension. Relatively few studies have examined the role of non-adherence in resistant hypertension. This review will address issues related to measurement of adherence, adherence ...
Vanderpool Rebecca R RR http://orcid.org/0000-0001-6038-0568 Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, - - 2014
Prognosis in pulmonary hypertension (PH) is largely determined by RV function. However, uncertainty remains about what metrics of RV function might be most clinically relevant. The purpose of this study was to assess the clinical relevance of metrics of RV functional adaptation to increased afterload. Patients referred for PH underwent ...
Niehoff Marc O MO Covance Laboratories GmbH, Kesselfeld 29, 48163 Muenster, Germany. Electronic address: - - 2014
The measurement of cardiovascular endpoints in standard toxicology studies remains a challenge as the routinely used non-invasive methods require physical restraint, causing an increase of sympathetic neural activity, leading to excitement and potentially hypertension in the experimental animals. In this study, a miniature telemetry blood pressure transmitter was used to ...
Kim Do Hoon DH Department of Family Medicine, College of Medicine, Korea University, Seoul, South - - 2014
First of all, we would like to thank the authors for an interesting and novel research on primary aldosteronism in hypertensive patients, which unexpectedly is a common problem in resistant hypertension, but is often overlooked. However, there are a few confusing points in statistical descriptions, while surely not intentional, that ...
Meng Guoliang G Key Laboratory of Cardiovascular Disease and Molecular Intervention, State Key Laboratory of Reproductive Medicine, Atherosclerosis Research Centre, Nanjing Medical University, Nanjing, - - 2014
Hydrogen sulfide (H2 S) has traditionally been viewed as a highly toxic gas; however, recent studies have implicated H2 S as a third member of the gasotransmitter family, exhibiting properties similar to nitric oxide (NO) and carbon monoxide (CO). Accumulating evidence has suggested that H2 S influenced a wide range ...
Tsika Evangelia P EP Cardiology Department, Asklepeion Hospital, Athens, - - 2014
It is known that a large proportion of patients with arterial hypertension are undertreated. This may result in an increase of the incidence of cardiovascular events. On the other hand, aggressive reduction of blood pressure may increase cardiovascular events (J-curve phenomenon) in certain populations. This phenomenon may be seen in ...
Chandra Alvin A Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, - - 2014
Obesity has been linked to the development of hypertension, but whether total adiposity or site-specific fat accumulation underpins this relationship is unclear. This study sought to determine the relationship between adipose tissue distribution and incident hypertension. Normotensive participants enrolled in the Dallas Heart Study were followed for a median of ...
Xu Xiaojing X Georgia Prevention Center, Institute of Prevention and Public Health, Georgia Regents University, Augusta, - - 2014
Nighttime blood pressure (BP) has been shown to be superior to daytime BP in predicting hypertension related target organ damage and cardiac mortality. In our Georgia Cardiovascular Twin Study, we showed that apart from the genes that also influence daytime BP, specific genetic determinants explained 44% and 67% of the ...
Ameloot Koen K Department of Cardiovascular Diseases, Medical Imaging Research Center, University Hospitals Leuven, Leuven, Belgium - - 2014
Right ventricular (RV) dp/dt is the instantaneous rate of RV pressure rise during early systole and is a surrogate marker of RV contractility. The main objective of this study was to evaluate the ability of echocardiographic Doppler obtained RV dp/dt to predict long-term survival in patients with pulmonary arterial hypertension ...
He Fu-Liang FL Fu-Liang He, Lei Wang, Zhen-Dong Yue, Hong-Wei Zhao, Fu-Quan Liu, Department of Interventional Therapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, - - 2014
To evaluate the feasibility of a second parallel transjugular intrahepatic portosystemic shunt (TIPS) to reduce portal venous pressure and control complications of portal hypertension. From January 2011 to December 2012, 10 cirrhotic patients were treated for complications of portal hypertension. The demographic data, operative data, postoperative recovery data, hemodynamic data, ...
Weltermann Birgitta M BM Institute for General Medicine, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Germany, - - 2014
Studies showed a positive association between appointment adherence and blood pressure control. In randomized-controlled trials blood pressure therapy was improved by recall systems. We analyze the effectiveness of an active telephone recall on blood pressure control for patients with low appointment adherence in regular primary care. This retrospective cohort study ...
Figueiredo Ricardo Rodrigues RR Federal University of São Paulo, Rua dos Otonis, 700, Vila Clementino, São Paulo, RJ, 04025-002, Brazil, - - 2014
Tinnitus is considered a multi-factorial symptom. Arterial hypertension has been cited as a tinnitus etiological factor. To assess the scientific evidence on the associations between arterial hypertension and tinnitus. A systematic review was performed using PubMed, ISI Web, Lilacs and SciELO scientific databases. This review included articles published in Portuguese, ...
Costello Benedict T BT Royal Hobart Hospital, Hobart - - 2014
Central blood pressure (BP) can be estimated noninvasively by analyzing brachial artery waveforms. In this study, our aim was to assess the validity of a brachial cuff-based (suprasystolic) technique for estimating central BP (CBPestimated) by comparison with invasive aortic BP (CBPinvasive). Eighty-four simultaneous CBPestimated (Pulsecor R7.0) and CBPinvasive measures were ...
Mourato Felipe A FA Círculo do Coração de Pernambuco, Pernambuco, Brazil; Laboratório de Imunopatologia Keizo Asami, Pernambuco, Brazil; and - - 2014
The blood pressure to height ratio (BP:HT) has been proposed as a simple method for identifying children with elevated BP. This procedure shows good accuracy for the screening of hypertension in adolescents but less so in younger children. Our aim in this study was to modify the BP:HT ratio and ...
Solini Anna A aDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa bDivision of Endocrinology and Metabolic Diseases, University of Verona, Verona cDiabetes Unit, Fondazione IRCCS 'Cà Granda-Ospedale Maggiore Policlinico', Milan dDiabetes Unit, University of Siena, Siena eEndocrinology and Diabetes Unit, Ospedali Riuniti, Bergamo fDepartment of Clinical and Experimental Medicine, University of Padua, Padua gDepartment of Clinical and Biological Sciences, University of Turin, Orbassano, Turin hDepartment of Medical Sciences, University of Foggia, Foggia iEndocrinology Unit, San Giuseppe Hospital, Milan jDepartment of Medical Sciences, University of Cagliari, Cagliari kDepartment of Clinical and Molecular Medicine, 'La Sapienza' University, Rome; - - 2014
The phenotype of resistant hypertension in patients with type 2 diabetes has been poorly characterized. This cross-sectional analysis of the large cohort from the Renal Insufficiency and Cardiovascular Events (RIACE) study was aimed at assessing the clinical correlates and association with complications of resistant hypertension in patients with type 2 ...
de Faria Ana Paula AP Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, - - 2014
Resistant hypertension (RH) is a multifactorial disease, frequently associated with obesity and characterized by blood pressure above goal (140/90 mm Hg) despite the concurrent use of ≥3 antihypertensive drugs of different classes. The mechanisms of obesity-related hypertension include, among others, aldosterone excess and inflammatory adipokines, which have demonstrated a significant role ...
Brower Kathryn A KA Department of Pharmacy, Iowa Methodist Medical Center, Des Moines, IA, - - 2014
Hypertension in the hospital setting is common; however, guidelines provide limited guidance specific to the inpatient setting. Acute antihypertensive treatment options can be limited in this setting by monitoring requirements of intravenous medications and patients' inability to take oral medications. A possible treatment choice used to treat acute hypertension is ...
Boonla Orachorn O Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen - - 2014
Oxidative stress plays a role in maintaining high arterial blood pressure and contributes to the vascular changes that lead to hypertension. Consumption of polyphenol-rich foods has demonstrated their beneficial role in the prevention and treatment of hypertension. Curcumin (CUR), a phenolic compound present in the rhizomes of turmeric, possesses cardiovascular ...
Fazeli Nima N Mechanical Engineering, University of Maryland, College Park, - - 2014
This paper demonstrates preliminary in-human validity of a novel subject-specific approach to estimation of central aortic blood pressure (CABP) from peripheral circulatory waveforms. In this "Individualized Transfer Function" (ITF) approach, CABP is estimated in two steps. First, the circulatory dynamics of the cardiovascular system are determined via model-based system identification, ...
Yang Li - - 2014
The prevalence of hypertension in China has risen dramatically in recent decades, but it is not well understood if hypertension is adequately controlled in the elderly population in Southern China. A provincial survey was performed in order to estimate the prevalence of hypertension control and the associated factors in the ...
Im Tae Seong TS Department of Radiology, Seoul National University Bundang Hospital, Gyeonggido, 436-707, - - 2014
Hypertension is known to be a strong risk factor for coronary atherosclerosis. We aimed to investigate the prevalence, severity, and plaque characteristics of coronary atherosclerosis according to grade of blood pressure (BP) using coronary CT angiography (CCTA) in asymptomatic adults. We enrolled 8,238 asymptomatic subjects who underwent coronary artery calcium ...
Sedaghat Sanaz S Departments of Epidemiology (S.S., R.P., A.G.U., A.H., B.H.Ch.S., O.H.F., A.D., M.A.I.), Internal Medicine (A.G.U.), Radiology (M.A.I.), and Neurology (M.A.I.), Erasmus University Medical Center, Rotterdam, The - - 2014
High levels of serum uric acid are associated with hypertension in observational studies. The aim of this study was to investigate the association of uric acid gene variants with blood pressure. We studied 5791 participants aged ≥55 years from the Rotterdam Study. Thirty gene variants identified for serum uric acid ...
Lankhorst Stephanie S From the Division of Pharmacology and Vascular Medicine, Department of Internal Medicine (S.L., M.H.W.K., J.H.M.v.E., A.H.J.D., A.H.v.d.M.) and Department of Medical Oncology, Erasmus MC Cancer Institute (S.S., R.H.J.M.), Erasmus Medical Center, Rotterdam, The Netherlands; Department of Pathology, Reinier de Graaf Groep, Delft, The Netherlands (F.M.M.S.); Department of Internal Medicine, Amphia Hospital, Breda, The Netherlands (M.H.W.K.); and Department of Pathology, Leiden University Medical Center, Leiden - - 2014
Common adverse effects of angiogenesis inhibition are hypertension and renal injury. To determine the most optimal way to prevent these adverse effects and to explore their interdependency, the following drugs were investigated in unrestrained Wistar Kyoto rats exposed to the angiogenesis inhibitor sunitinib: the dual endothelin receptor antagonist macitentan; the ...
Safar Michel E ME Paris Descartes University, AP-HP, Diagnosis and Therapeutic Center, Paris, France; - - 2014
Patho-physiological and pharmacological studies have consistently noticed that, with the exception of subjects with end-stage renal disease, total intravascular blood volume is not increased in patients with chronic hypertension. Because the mean circulatory pressure is enhanced in such subjects, it was postulated that the compliance of the cardiovascular system could ...
Batisky Donald L DL Pediatric Hypertension Program, Children's Healthcare of Atlanta, Emory - Children's Center, 2015 Uppergate Drive North East, Atlanta, GA 30322, USA. Electronic address: - - 2014
The incidence of neonatal hypertension (HTN) remains low, at less than 2%, and its etiology is varied. Strict definitions of HTN in neonates are unavailable, and the decision to treat is based on opinion rather than evidence. More studies are needed to define normal blood pressure in neonates and to ...
Iyer Dushyant D The University of New South Wales, Sydney, NSW, Australia. - - 2014
To investigate screening variables identifying patients at risk of developing intra-abdominal hypertension (IAH) after cardiac surgery. Prospective observational study in a tertiary general intensive care unit. One hundred and eight patients admitted to the ICU after cardiac surgery, with measurements of intraabdominal pressure (IAP). Routinely collected clinical, physiological and biochemical ...
Porter Angela K AK Charles George VA Medical Center, Asheville, NC 28805. - - 2014
Two-thirds of Americans who are prescribed antihypertensive medications are not at a blood pressure (BP) goal of less than  140/90 mmHg, and low adherence is identified as a primary cause of inadequate control. Improved adherence to antihypertensive medications has been shown to enhance BP control and reduce the risk of ...
Milouk Fatima Zahra FZ Unit of Cardiology A, Ibn Sina University Hospital, Rabat 10000, - - 2014
Primary Hypertension (HT) is the most prevalent cardiovascular disorder worldwide and is accompanied by significant morbidity and mortality. The present study aimed to investigate the kinetics of orthostatic Blood Pressure (BP) in primary hypertensive patients during the change from supine position to standing position as well as during the standing ...
Babaee Beigi Mohammad Ali MA Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IR - - 2014
Hypertension is the main risk factor for cardiovascular diseases and stroke. Blood pressure control is a challenge for healthcare providers and the rate of blood pressure control is not more than 50% worldwide. The present study aimed to determine the effectiveness of a short-term educational program on the level of ...
Giorgini Paolo P Division of Internal Medicine, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, University of L'Aquila, L'Aquila, - - 2014
Hypertension guidelines recommend following published standardized protocols to obtain accurate blood pressure (BP) readings in clinical practice. However, the various measurement techniques among clinical trials that provide the basis for evidence-based management have not been evaluated or compared with guideline recommendations. We reviewed published information regarding BP measurement in clinical ...
Neupane Dinesh D Department of Public Health (DN, PK), Center for Global Health, Aarhus University, Aarhus, Denmark; Rural Clinical School (CSM), University of New South Wales, Sydney, Australia; Unit of Health Promotion (RS, BG), University of Southern Denmark, Esbjerg, Denmark; School of Public Health (VK), Curtin University, Perth, Australia; Nepal Development Society (SRM), Kathmandu, Nepal; and Department of Public Health (BC), Institute of General Medical Practice, Aarhus University, Aarhus, - - 2014
Hypertension is a leading attributable risk factor for mortality in South Asia. However, a systematic review on prevalence and risk factors for hypertension in the region of the South Asian Association for Regional Cooperation (SAARC) has not carried out before.The study was conducted according to the Meta-Analysis of Observational Studies ...
Chaturvedi Swasti S Department of Paediatrics, Christian Medical College, Vellore, India. - - 2014
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence of end organ damage and are at risk of ...
Merati G G Department of Biomedical Sciences for Health, University of Milan, Milan, Italy. - - 2014
In selected hypertensive subjects, cardiovascular adaptation to warm environments may be inadequate or even harmful: heating associated to mudpack therapy may cause unexpected hypotension. How different antihypertensive drugs may affect the cardiovascular response to mudpack therapy is poorly studied. To evaluate the effects of β-blockers and angiotensin II receptor antagonists/ACE ...
Kim Mi-Seon MS Department of Obstetrics and Gynecology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, - - 2014
This report describes an 18-year-old woman presenting with abdominal distension, left flank pain, and hypertension. She had a huge abdominal mass, diagnosed as a mesenteric desmoid-type fibromatosis, causing compression of the left external iliac vessels and ureter, as well as elevated renin concentration and hypertension. After surgical removal of the ...
Adib-Hajbaghery Mohsen M Department of Medical Surgical Nursing, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, - - 2014
Studies indicate that hypertension is prevalent in Iran, however, the reports are heterogeneous. The aim of this study was to estimate the incidence of hypertension and the rate of follow-up in a sample of population over 30 years old in Kashan city. A descriptive study was conducted on people screened ...
Ayaz Teslime T Department of Internal Medicine, Recep Tayyip Erdoğan University, Education and Research Hospital, Rize, - - 2014
Left ventricular hypertrophy (LVH), a sign of subclinical cardiovascular disease, is an important predictor of cardiovascular morbidity and mortality. The aim of our study was to determine the association of left ventricular mass (LVM) with possible causative anthropometric and biochemical parameters as well as carotid intima-media thickness (CIMT) and brachial ...
Jasińska-Stroschein Magdalena - - 2014
Abstract There is considerable interest in the pleiotropic effects of statins and their potential role in the treatment of pulmonary hypertension. Previous experimental findings indicate that a combination of lipophilic statins with phosphodiesterase type-5 inhibitor, sildenafil, can offer preventive effects on rat monocrotaline-induced pulmonary hypertension. The present study is aimed ...
Majidi Shahram S Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, - - 2014
There have been growing concerns regarding delayed aneurysm rupture subsequent to the flow-diverting stent deployment. Therefore, more investigations are needed regarding hemodynamic changes secondary to flow-diverting stent deployment. To study intra-aneurysmal and perianeurysmal pressures after partial and complete flow impairment into the aneurysm. A silicone model of an 8-mm-sized aneurysm ...
Patel Rachna S RS Shivrath Centre of Excellence in Clinical Research, Ahmedabad, - - 2014
To estimate and compare the cost-effectiveness and safety of nebivolol with sustained-release metoprolol in reducing blood pressure by 1 mm of Hg per day in hypertensive patients. This was a prospective, randomized, open label, observational analysis of cost-effectiveness, in a questionnaire-based fashion to compare the cost of nebivolol (2.5 mg, ...
- - 2014
160/90 mmHg, according to the inclusion criteria used in trials. But the harm-benefit balance is uncertain for patients whose diastolic blood pressure is between 90 and 100 mmHg.
- - 2014
We concluded in 2004 that the first-choice treatment for hypertension in adults was single-agent therapy with the thiazide diuretic chlortalidone or, when this drug is not available, the thiazide diuretic hydrochlorothiazide. As of early 2014, does evidence challenge this choice in adults without diabetes or cardiovascular or renal disease? To ...
Priyadharsini R P RP Department of Pharmacology, JIPMER, Gorimedu, Puducherry, - - 2014
Hypertension was induced in male Sprague Dawley rats with twice weekly administration of deoxycorticosterone acetate (DOCA) salt (20 mg/kg s.c) for 4 weeks. They were divided into eight groups of six animals each viz., hypertensive control, standard (prazosin 1 mg/kg), cleistanthin A 12.5, 25, 50 mg/kg and cleistanthin B 12.5, ...
Oh Jieun J 0000-0001-9429-9602 Department of Internal Medicine, Hallym University College of Medicine, Hallym Kidney Research Institute, Seoul, - - 2014
No large-scale studies have investigated the association between salt intake and hypertension in Korean population. To investigate the relationship of blood pressure to salt consumption, we analyzed data from 19,476 participants in the 2009-2011 Korean National Health and Nutritional Examination Survey (KNHANES). Urinary sodium excretion over 24-hr (24HUNa) was estimated ...
Jeon Sang-Beom SB Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Malignant cerebral edema following ischemic stroke is life threatening, as it can cause inadequate blood flow and perfusion leading to irreversible tissue hypoxia and metabolic crisis. Increased intracranial pressure and brain shift can cause herniation syndrome and finally brain death. Multiple randomized clinical trials have shown that preemptive decompressive hemicraniectomy ...
Salaudeen Ag A Department of Epidemiology and Community Health, University of Ilorin, Ilorin, - - 2014
High job strain, mental stress, sedentary lifestyle, increase in BMI are among the factors associated with significantly higher incidence of hypertension. The job of bank employees is both sedentary in nature and accompanies high mental stress. The aim of this study is to assess the level of knowledge of risk ...
Deb Amit K AK Department of Ophthalmology, Jawaharlal Institute of Post Graduate Medical Education and Research, Gorimedu, - - 2014
To study the relationship between blood pressure (BP), intraocular pressure (IOP), mean ocular perfusion pressure (MOPP) and primary open angle glaucoma (POAG) in patients with hypertension and compare it to a control group of normotensives. Cross-sectional observational study. A total of 108 subjects with primary hypertension and 100 age-matched controls ...
Rowan Christopher G CG American Medical Group Association, Alexandria, VA, - - 2014
To describe initial antihypertensive management relative to important aspects of JNC7 hypertension guidelines, to identify predictors of receiving JNC7 discordant therapy, and to determine the association between receiving JNC7-concordant antihypertensive treatment and achieving blood pressure (BP) control. This study focused on aspects of the JNC7 guidelines which are consistent with ...
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