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Brower Kathryn A KA Department of Pharmacy, Iowa Methodist Medical Center, Des Moines, IA, - - 2014
Hypertension in the hospital setting is common; however, guidelines provide limited guidance specific to the inpatient setting. Acute antihypertensive treatment options can be limited in this setting by monitoring requirements of intravenous medications and patients' inability to take oral medications. A possible treatment choice used to treat acute hypertension is ...
Boonla Orachorn O Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen - - 2014
Oxidative stress plays a role in maintaining high arterial blood pressure and contributes to the vascular changes that lead to hypertension. Consumption of polyphenol-rich foods has demonstrated their beneficial role in the prevention and treatment of hypertension. Curcumin (CUR), a phenolic compound present in the rhizomes of turmeric, possesses cardiovascular ...
Fazeli Nima N Mechanical Engineering, University of Maryland, College Park, - - 2014
This paper demonstrates preliminary in-human validity of a novel subject-specific approach to estimation of central aortic blood pressure (CABP) from peripheral circulatory waveforms. In this "Individualized Transfer Function" (ITF) approach, CABP is estimated in two steps. First, the circulatory dynamics of the cardiovascular system are determined via model-based system identification, ...
Yang Li - - 2014
The prevalence of hypertension in China has risen dramatically in recent decades, but it is not well understood if hypertension is adequately controlled in the elderly population in Southern China. A provincial survey was performed in order to estimate the prevalence of hypertension control and the associated factors in the ...
Im Tae Seong TS Department of Radiology, Seoul National University Bundang Hospital, Gyeonggido, 436-707, - - 2014
Hypertension is known to be a strong risk factor for coronary atherosclerosis. We aimed to investigate the prevalence, severity, and plaque characteristics of coronary atherosclerosis according to grade of blood pressure (BP) using coronary CT angiography (CCTA) in asymptomatic adults. We enrolled 8,238 asymptomatic subjects who underwent coronary artery calcium ...
Sedaghat Sanaz S Departments of Epidemiology (S.S., R.P., A.G.U., A.H., B.H.Ch.S., O.H.F., A.D., M.A.I.), Internal Medicine (A.G.U.), Radiology (M.A.I.), and Neurology (M.A.I.), Erasmus University Medical Center, Rotterdam, The - - 2014
High levels of serum uric acid are associated with hypertension in observational studies. The aim of this study was to investigate the association of uric acid gene variants with blood pressure. We studied 5791 participants aged ≥55 years from the Rotterdam Study. Thirty gene variants identified for serum uric acid ...
Lankhorst Stephanie S From the Division of Pharmacology and Vascular Medicine, Department of Internal Medicine (S.L., M.H.W.K., J.H.M.v.E., A.H.J.D., A.H.v.d.M.) and Department of Medical Oncology, Erasmus MC Cancer Institute (S.S., R.H.J.M.), Erasmus Medical Center, Rotterdam, The Netherlands; Department of Pathology, Reinier de Graaf Groep, Delft, The Netherlands (F.M.M.S.); Department of Internal Medicine, Amphia Hospital, Breda, The Netherlands (M.H.W.K.); and Department of Pathology, Leiden University Medical Center, Leiden - - 2014
Common adverse effects of angiogenesis inhibition are hypertension and renal injury. To determine the most optimal way to prevent these adverse effects and to explore their interdependency, the following drugs were investigated in unrestrained Wistar Kyoto rats exposed to the angiogenesis inhibitor sunitinib: the dual endothelin receptor antagonist macitentan; the ...
Safar Michel E ME Paris Descartes University, AP-HP, Diagnosis and Therapeutic Center, Paris, France; - - 2014
Patho-physiological and pharmacological studies have consistently noticed that, with the exception of subjects with end-stage renal disease, total intravascular blood volume is not increased in patients with chronic hypertension. Because the mean circulatory pressure is enhanced in such subjects, it was postulated that the compliance of the cardiovascular system could ...
Batisky Donald L DL Pediatric Hypertension Program, Children's Healthcare of Atlanta, Emory - Children's Center, 2015 Uppergate Drive North East, Atlanta, GA 30322, USA. Electronic address: - - 2014
The incidence of neonatal hypertension (HTN) remains low, at less than 2%, and its etiology is varied. Strict definitions of HTN in neonates are unavailable, and the decision to treat is based on opinion rather than evidence. More studies are needed to define normal blood pressure in neonates and to ...
Iyer Dushyant D The University of New South Wales, Sydney, NSW, Australia. - - 2014
To investigate screening variables identifying patients at risk of developing intra-abdominal hypertension (IAH) after cardiac surgery. Prospective observational study in a tertiary general intensive care unit. One hundred and eight patients admitted to the ICU after cardiac surgery, with measurements of intraabdominal pressure (IAP). Routinely collected clinical, physiological and biochemical ...
Porter Angela K AK Charles George VA Medical Center, Asheville, NC 28805. - - 2014
Two-thirds of Americans who are prescribed antihypertensive medications are not at a blood pressure (BP) goal of less than  140/90 mmHg, and low adherence is identified as a primary cause of inadequate control. Improved adherence to antihypertensive medications has been shown to enhance BP control and reduce the risk of ...
Milouk Fatima Zahra FZ Unit of Cardiology A, Ibn Sina University Hospital, Rabat 10000, - - 2014
Primary Hypertension (HT) is the most prevalent cardiovascular disorder worldwide and is accompanied by significant morbidity and mortality. The present study aimed to investigate the kinetics of orthostatic Blood Pressure (BP) in primary hypertensive patients during the change from supine position to standing position as well as during the standing ...
Babaee Beigi Mohammad Ali MA Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, IR - - 2014
Hypertension is the main risk factor for cardiovascular diseases and stroke. Blood pressure control is a challenge for healthcare providers and the rate of blood pressure control is not more than 50% worldwide. The present study aimed to determine the effectiveness of a short-term educational program on the level of ...
Giorgini Paolo P Division of Internal Medicine, Department of Life, Health and Environmental Sciences, San Salvatore Hospital, University of L'Aquila, L'Aquila, - - 2014
Hypertension guidelines recommend following published standardized protocols to obtain accurate blood pressure (BP) readings in clinical practice. However, the various measurement techniques among clinical trials that provide the basis for evidence-based management have not been evaluated or compared with guideline recommendations. We reviewed published information regarding BP measurement in clinical ...
Neupane Dinesh D Department of Public Health (DN, PK), Center for Global Health, Aarhus University, Aarhus, Denmark; Rural Clinical School (CSM), University of New South Wales, Sydney, Australia; Unit of Health Promotion (RS, BG), University of Southern Denmark, Esbjerg, Denmark; School of Public Health (VK), Curtin University, Perth, Australia; Nepal Development Society (SRM), Kathmandu, Nepal; and Department of Public Health (BC), Institute of General Medical Practice, Aarhus University, Aarhus, - - 2014
Hypertension is a leading attributable risk factor for mortality in South Asia. However, a systematic review on prevalence and risk factors for hypertension in the region of the South Asian Association for Regional Cooperation (SAARC) has not carried out before.The study was conducted according to the Meta-Analysis of Observational Studies ...
Chaturvedi Swasti S Department of Paediatrics, Christian Medical College, Vellore, India. - - 2014
Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence of end organ damage and are at risk of ...
Merati G G Department of Biomedical Sciences for Health, University of Milan, Milan, Italy. - - 2014
In selected hypertensive subjects, cardiovascular adaptation to warm environments may be inadequate or even harmful: heating associated to mudpack therapy may cause unexpected hypotension. How different antihypertensive drugs may affect the cardiovascular response to mudpack therapy is poorly studied. To evaluate the effects of β-blockers and angiotensin II receptor antagonists/ACE ...
Kim Mi-Seon MS Department of Obstetrics and Gynecology, Seoul Paik Hospital, Inje University College of Medicine, Seoul, - - 2014
This report describes an 18-year-old woman presenting with abdominal distension, left flank pain, and hypertension. She had a huge abdominal mass, diagnosed as a mesenteric desmoid-type fibromatosis, causing compression of the left external iliac vessels and ureter, as well as elevated renin concentration and hypertension. After surgical removal of the ...
Adib-Hajbaghery Mohsen M Department of Medical Surgical Nursing, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, - - 2014
Studies indicate that hypertension is prevalent in Iran, however, the reports are heterogeneous. The aim of this study was to estimate the incidence of hypertension and the rate of follow-up in a sample of population over 30 years old in Kashan city. A descriptive study was conducted on people screened ...
Ayaz Teslime T Department of Internal Medicine, Recep Tayyip Erdoğan University, Education and Research Hospital, Rize, - - 2014
Left ventricular hypertrophy (LVH), a sign of subclinical cardiovascular disease, is an important predictor of cardiovascular morbidity and mortality. The aim of our study was to determine the association of left ventricular mass (LVM) with possible causative anthropometric and biochemical parameters as well as carotid intima-media thickness (CIMT) and brachial ...
Jasińska-Stroschein Magdalena - - 2014
Abstract There is considerable interest in the pleiotropic effects of statins and their potential role in the treatment of pulmonary hypertension. Previous experimental findings indicate that a combination of lipophilic statins with phosphodiesterase type-5 inhibitor, sildenafil, can offer preventive effects on rat monocrotaline-induced pulmonary hypertension. The present study is aimed ...
Majidi Shahram S Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, - - 2014
There have been growing concerns regarding delayed aneurysm rupture subsequent to the flow-diverting stent deployment. Therefore, more investigations are needed regarding hemodynamic changes secondary to flow-diverting stent deployment. To study intra-aneurysmal and perianeurysmal pressures after partial and complete flow impairment into the aneurysm. A silicone model of an 8-mm-sized aneurysm ...
Patel Rachna S RS Shivrath Centre of Excellence in Clinical Research, Ahmedabad, - - 2014
To estimate and compare the cost-effectiveness and safety of nebivolol with sustained-release metoprolol in reducing blood pressure by 1 mm of Hg per day in hypertensive patients. This was a prospective, randomized, open label, observational analysis of cost-effectiveness, in a questionnaire-based fashion to compare the cost of nebivolol (2.5 mg, ...
- - 2014
160/90 mmHg, according to the inclusion criteria used in trials. But the harm-benefit balance is uncertain for patients whose diastolic blood pressure is between 90 and 100 mmHg.
- - 2014
We concluded in 2004 that the first-choice treatment for hypertension in adults was single-agent therapy with the thiazide diuretic chlortalidone or, when this drug is not available, the thiazide diuretic hydrochlorothiazide. As of early 2014, does evidence challenge this choice in adults without diabetes or cardiovascular or renal disease? To ...
Priyadharsini R P RP Department of Pharmacology, JIPMER, Gorimedu, Puducherry, - - 2014
Hypertension was induced in male Sprague Dawley rats with twice weekly administration of deoxycorticosterone acetate (DOCA) salt (20 mg/kg s.c) for 4 weeks. They were divided into eight groups of six animals each viz., hypertensive control, standard (prazosin 1 mg/kg), cleistanthin A 12.5, 25, 50 mg/kg and cleistanthin B 12.5, ...
Oh Jieun J 0000-0001-9429-9602 Department of Internal Medicine, Hallym University College of Medicine, Hallym Kidney Research Institute, Seoul, - - 2014
No large-scale studies have investigated the association between salt intake and hypertension in Korean population. To investigate the relationship of blood pressure to salt consumption, we analyzed data from 19,476 participants in the 2009-2011 Korean National Health and Nutritional Examination Survey (KNHANES). Urinary sodium excretion over 24-hr (24HUNa) was estimated ...
Jeon Sang-Beom SB Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
Malignant cerebral edema following ischemic stroke is life threatening, as it can cause inadequate blood flow and perfusion leading to irreversible tissue hypoxia and metabolic crisis. Increased intracranial pressure and brain shift can cause herniation syndrome and finally brain death. Multiple randomized clinical trials have shown that preemptive decompressive hemicraniectomy ...
Rowan Christopher G CG American Medical Group Association, Alexandria, VA, - - 2014
To describe initial antihypertensive management relative to important aspects of JNC7 hypertension guidelines, to identify predictors of receiving JNC7 discordant therapy, and to determine the association between receiving JNC7-concordant antihypertensive treatment and achieving blood pressure (BP) control. This study focused on aspects of the JNC7 guidelines which are consistent with ...
Hill Michael R MR Center for Cardiovascular Simulation, Institute for Computational Engineering and Sciences, Department of Biomedical Engineering, The University of Texas at Austin, 201 East 24th Street, University Station, C0200, POB 5.236, Austin, TX, 78712-0027, - - 2014
Right ventricular (RV) failure in response to pulmonary hypertension (PH) is a severe disease that remains poorly understood. PH-induced pressure overload leads to changes in the RV free wall (RVFW) that eventually results in RV failure. While the development of computational models can benefit our understanding of the onset and ...
Sonter Jennifer J aSchool of Health Sciences bPriority Research Centre for Physical Activity and Nutrition, University of Newcastle, Ourimbah, New South Wales, - - 2014
The aim of this study was to determine the inter-rater reliability of automated devices for the measurement of toe systolic blood pressure (TSBP) and the toe brachial index (TBI). Toe and brachial systolic blood pressures were measured in 40 participants by two podiatrists using SysToe and MicroLife automated devices. Intraclass ...
Rosa-Bray M M Grifols Plasma Operations, Los Angeles, CA, - - 2014
Donor plasmapheresis involves the removal of a weight-adjusted volume of plasma and the return of cellular components to the donor. Although plasma volume generally returns to normal, some residual effect on vital signs may be possible. This analysis was performed to determine the possible effects of plasmapheresis on blood pressure. ...
Olzowy Bernhard B 1 Department of Otorhinolaryngology, Head and Neck Surgery, University of Rostock Medical Center , Rostock, Germany - - 2014
Abstract Olzowy, Bernhard, Simon Abendroth, Gregor von Gleichenstein, Klaus Mees, and Klaus Stelter. No evidence of intracranial hypertension in trekkers with acute mountain sickness when assessed noninvasively with distortion product otoacoustic emissions. High Alt Med Biol 15:000-000, 2014.-Aims: The role of intracranial hypertension in acute mountain sickness (AMS) is a ...
Heifetz Eliyahu M EM Department of Accounting and Data Management, Lev Academic Center, Jerusalem, - - 2014
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism was found to be associated with hypertension. High blood pressure (BP) is a major risk factor for cardiovascular disease, gestational hypertension, and high-risk pregnancy. BP is a complex trait strongly associated with blood lipid parameters. However, studies of the effect of MTHFR C677T polymorphism on ...
Abi Aad Simon S Mount Sinai - Luke's Roosevelt Hospital Center, New York, NY, USA. Electronic address: - - 2014
Hypertension is a common adverse effect of certain anti neoplastic therapy. The incidence and severity of hypertension are dependent mainly on the type and the dose of the drug. We reviewed the literature for studies that reported the effect of anti neoplastic agents on blood pressure in patients with malignancies. ...
Gee Marianne E ME Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, ON, - - 2014
Surveillance and monitoring of cardiovascular risk factors including raised blood pressure are critical to informing efforts to prevent and control cardiovascular disease. Yet, many countries lack the capacity for adequate national surveillance. Furthermore, hypertension indicators are often reported in different ways, which hampers the ability to compare and assess progress. ...
Liu Wenjin W Center for Kidney Disease, 2nd Affiliated Hospital, Nanjing Medical University, Nanjing, - - 2014
Although ambulatory blood pressure (ABP) monitoring (ABPM) is often considered to have an advantage over dialysis unit blood pressure (BP) in dialysis patients, the exact relationship between these two measurements of BP has not been well determined. In a cohort of 90 Chinese dialysis patients, agreement between dialysis unit BP ...
Mejia-Lancheros Cilia - - 2014
Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. Cross-sectional study, embedded within ...
Dobrowolski Piotr P Department of Congenital Heart Diseases, Institute of Cardiology, Warsaw, Poland; - - 2014
Diastolic dysfunction has been shown to be an independent factor of cardiovascular diseases in patients with hypertension. Very often, obstructive sleep apnea (OSA) and metabolic syndrome (MS) coexist with resistant hypertension (RHTN) and may lead to diastolic dysfunction. Thus, the purpose of this study was to investigate whether OSA and ...
Kumar Rahul R Functional Genomics Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India; Present address: Division of Pulmonary Sciences and Critical Care Medicine, School of Medicine, University of Colorado, Denver, Colorado (R.K.); Department of Pediatrics, Division of Respiratory Medicine, University of California San Diego, La Jolla, California (T.S.); Research Center for Molecular Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran - - 2014
This study investigates the contribution of genetic interactions between the β-2 adrenergic receptor (ADRB2) and nitric oxide synthase (NOS3) genes to the complex etiology of hypertension. Using single nucleotide polymorphism (SNP) markers, we studied potential interactions between ADRB2 and NOS3 variants and their correlation with clinical, biochemical, and expression levels ...
White Laura H LH aSleep Research Laboratory, Toronto Rehabilitation Institute bCentre for Sleep Medicine and Circadian Biology of the University of Toronto cDepartment of Medicine of the University Health Network, Toronto General Hospital and Mount Sinai Hospital dLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital eFaculty of Medicine, University of Toronto, Toronto, Ontario, - - 2014
Obstructive sleep apnoea (OSA) and hypertension frequently coexist, and both are associated with higher night-time than daytime urine sodium excretion rate (UNaV). However, the relative contribution of each condition is unknown. We compared the circadian pattern of UNaV in hypertensive and normotensive patients with and without OSA. Hypertensive [blood pressure ...
Lokhandwala Adil A Adil Lokhandwala, Department of Internal Medicine, University of Arizona College of Medicine at South Campus, Tucson, AZ 85713, United - - 2014
Resistant hypertension (RHTN) is a commonly encountered clinical problem and its management remains a challenging task for healthcare providers. The prevalence of true RHTN has been difficult to assess due to pseudoresistance and secondary hypertension. Atherosclerotic renal artery stenosis (RAS) has been associated as a secondary cause of RHTN. Initial ...
Sharma Prashant P Mayo Clinic, Hospital - - 2014
Hypertension is a major public health problem and despite adequate pharmacological treatment, blood pressure remains uncontrolled in a subset of patients with hypertension. Renal sympathetic denervation is a percutaneous catheter-based treatment for select patients with resistant hypertension. In this article, we discuss the development of this intervention, its role in ...
Kario Kazuomi K From the Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan (K.K.); Keio University, Yokohama, Japan (I.S.); The Life Planning Center Foundation, Tokyo, Japan (T.K.); Department of Biostatistics, Graduate School of Medical Science Kyoto Prefectural University of Medicine, Kyoto, Japan (S.T.); Daiichi Sankyo Co, Ltd, Tokyo, Japan (Y.I., Y.M., F.K.); and Shin-Oyama City Hospital, Oyama, Japan (K.S.). - - 2014
This study aimed to investigate the relationship between on-treatment morning home blood pressure (HBP) and incidence of cardiovascular events using data from the Home Blood Pressure Measurement With Olmesartan Naive Patients to Establish Standard Target Blood Pressure (HONEST) study, a prospective observational study of 21 591 outpatients with essential hypertension ...
Crichton Georgina E GE From the Nutritional Physiology Research Centre, University of South Australia, Adelaide, Australia (G.E.C.); Centre d'Etudes en Santé, Centre de Recherche Public Santé, Strassen, Grand-Duchy of Luxembourg (G.E.C.); Department of Psychology (M.F.E., R.V.T., M.A.R.) and Graduate School of Biomedical Sciences and Engineering (M.F.E., M.A.R.), University of Maine, Orono; and Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD (G.A.D.). - - 2014
The objective was to investigate the association between variability in blood pressure (BP) and cognitive function for sitting, standing, and reclining BP values and variability derived from all 15 measures. In previous studies, only sitting BP values have been examined, and only a few cognitive measures have been used. A ...
Fok Henry H From the British Heart Foundation Centre (H.F., A.G., S.B., B.J., Y.L., P.C.) and Division of Imaging Sciences and Biomedical Engineering (S.E., J.A.), King's College London, London, United Kingdom; and Guy's and St Thomas Foundation Trust Hospital, London, United Kingdom - - 2014
Pulsatile components of blood pressure may arise from forward (ventricular generated) or backward wave travel in the arterial tree. The objective of this study was to determine the relative contributions of forward and backward waves to pulsatility. We used wave intensity and wave separation analysis to determine pulsatile components of ...
Li Edmond Ck EC Island Medical Program, University of British Columbia, Royal Jubilee Hospital, Coronation Annex, 1952 Bay Street, Victoria, BC, Canada, - - 2014
Angiotensin converting enzyme inhibitors (ACE inhibitors) and angiotensin receptor blockers (ARBs) are widely prescribed for primary hypertension (systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg). However, while ACE inhibitors have been shown to reduce mortality and morbidity in placebo-controlled trials, ARBs have not. Therefore, a ...
Izzi Francesca F Neurophysiopathology Unit, Sleep Medicine Center, Department of Systems Medicine, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, - - 2014
To investigate cardiovascular autonomic function in patients with restless leg syndrome (RLS) by means of cardiovascular reflexes and heart rate variability (HRV) during wakefulness. Twelve RLS patients and 14 controls underwent cardiovascular function tests including head-up tilt test (HUTT), Valsalva maneuver, deep breathing, hand grip, and cold face. HRV analysis ...
Malem David N DN Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery , Queen Square, London , - - 2014
Introduction. Idiopathic normal pressure hydrocephalus (iNPH) is a shunt- reversible syndrome of the elderly. Shunt management is aimed at achieving a balance between clinical improvement and the complications associated with overdrainage. Although clinical improvement occurs at low pressure, these benefits may be negated by the increase in complication rates observed ...
Sheppard James P JP aNuffield Department of Primary Care Health Sciences, University of Oxford bNational Institute for Health Research School for Primary Care Research, Radcliffe Observatory Quarter, Woodstock Road, Oxford cPrimary Care Clinical Sciences, University of Birmingham, Edgbaston, Birmingham dSchool of Psychology, Darwin Building, University of Central Lancashire, Preston, Lancashire ePrimary Care Unit, Institute of Public Health, University of Cambridge, Cambridge, Cambridgeshire fSchool of Medicine, University of Southampton, University Road, Southampton gInstitute of Cardiovascular Sciences, University College London (UCL) and National Institute for Health Research UCL Hospitals Biomedical Research Centre, London, - - 2014
Identification of people with lower (white-coat effect) or higher (masked effect) blood pressure at home compared to the clinic usually requires ambulatory or home monitoring. This study assessed whether changes in SBP with repeated measurement at a single clinic predict subsequent differences between clinic and home measurements. This study used ...
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