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Mancia Giuseppe G aUniversity of Milano-Bicocca, Centro Interuniversitario di Fisiologia Clinica e Ipertensione, Istituto Auxologico Italiano IRCCS, Milan, Italy bFoundation Medical Research Institutes, Paris, France cInstituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil dCHU Avicenne, Unité Médecine Interne-Hypertension Artérielle, Bobigny, France eUniversity of Pisa/School of Medicine, Pisa, Italy fInstituto de Corazón de Querétaro, Querétaro, Mexico gMinistry of Health of the Russian Federation, Cardiology Research Complex, Moscow, Russia hServicio de Medicina Interna, Unidad Metabólico-Vascular, Hospital Universitario La Paz, IdiPaz, Madrid, - - 2014
An international double-blind, parallel-group, randomized controlled trial was performed to determine the efficacy and safety of a new first-line strategy in mild to moderate hypertension based on a single-pill combination of perindopril/amlodipine versus a validated stepped-care strategy (initiation with valsartan monotherapy, up-titrating to valsartan/amlodipine after 2 months). At inclusion, patients ...
Martins-Meneses Daniele Tavares DT Biosciences Department, Federal University of Sao Paulo, Santos, - - 2014
Physical exercise has been used in the treatment of hypertension. However, there are few methods researched and shown beneficial for treatment of hypertension. The objective was to evaluate the effect of Mat Pilates training (MP) on blood pressure (BP) of hypertensive women medicated with antihypertensive drugs. 44 hypertensive women (50.5±6.3years ...
Chan Vincent V Division of Cardiac Surgery, University of Ottawa, Ottawa, Ontario, Canada; Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: - - 2014
The evidence supporting early surgical intervention in patients with chronic asymptomatic mitral regurgitation (MR) is steadily accumulating. Although left ventricular (LV) enlargement and preoperative pulmonary hypertension are considered when deciding on surgical intervention, the threshold above which these factors influence clinical outcomes remains poorly defined. One-hundred fifty asymptomatic patients of ...
Liang Yajun Y Department of Epidemiology, Capital Institute of Pediatrics, Beijing, China; School of Public Health, Jining Medical University, Jining, Shandong, - - 2014
There are few studies investigating the long-term association between childhood blood pressure (BP) and adult cardiovascular remodeling. We seek to examine the effect of elevated childhood BP on cardiovascular remodeling in early or middle adulthood. We used the "Beijing BP Cohort Study", where 1259 subjects aged 6-18years old were followed ...
Henry Thea L TL Bresmed Health Solutions, North Church House, Sheffield, S1 2DW, United - - 2014
Abstract Objectives Safety and efficacy data for catheter-based renal denervation (RDN) in the treatment of resistant hypertension have been used to estimate the cost effectiveness of this approach. However, there are no Dutch-specific analyses. We examined the cost effectiveness of RDN from the perspective of the healthcare payer in The ...
He Zheng Z Dept of Optometry & Vision Sciences, The University of Melbourne, Level 1, Kenneth Myer Building, 30 Royal Parade, Parkville, Melbourne, Victoria, 3010, - - 2014
Purpose: to consider the effect of chronic arterial hypertension on the susceptibility of the retina to acute intraocular (IOP) challenge. Methods: Anesthetized adult Long-Evans rats with normal (n=5, receiving saline subcutaneously), chronic high blood pressure (BP) for 4 weeks (n=15, Angiotensin II subcutaneously) and acute high BP for 1 hour ...
Muntner Paul P Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA; - - 2014
Several ambulatory blood pressure monitoring (ABPM) measures have been associated with increased cardiovascular disease risk independent of clinic blood pressure (BP). African Americans have higher clinic BP compared with Whites but few data are available on racial differences in ABPM measures. We compared ABPM measures between African American (n = ...
Suzuki Hiromichi H Department of Nephrology, Saitama Medical University 38 Morohonngo, Moroyama machi, Iruma gun, Saitama, 350-0495, Japan - - 2014
The guidelines for hypertension require the presence of compelling indications for pharmacological management of hypertension associated with various diseases. Data mainly obtained through randomized controlled trials have provided evidence supporting effectiveness of the combination of losartan (Lo) and hydrochlorothiazide (HCTZ) for management of hypertensive patients. However, there have been few ...
Saladini Francesca F Department of Medicine, University of Padova, Padova, - - 2014
The aim of the present study was to investigate the association of physical activity with small artery elasticity in the early stage of hypertension. We examined 366 young-to-middle-age stage 1 hypertensives (mean blood pressure 145.6±10.3/92.5±5.8 mmHg), divided into two categories of physical activity, sedentary (n=264) and non-sedentary (n=102) subjects. The ...
Zielinska-Krawczyk Monika M Department of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw, Warsaw, - - 2014
We report intriguing preliminary observations on the effect of cough on pleural pressure changes during therapeutic thoracentesis. We found that cough-related elevation of pleural pressure persisted even when the cough had stopped. Thus, we hypothesize that cough during therapeutic thoracentesis may have a beneficial effect preventing the excessive drop in ...
Ott Christian C Department of Nephrology and Hypertension, University Hospital of the Friedrich-Alexander-University Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, - - 2014
The underlying pathophysiologic concept of diverse invasive devices to treat resistant hypertension (e.g., sympathetic denervation, carotid sinus nerve stimulation) is known for a long time. Since the pioneering work in the 1940s in humans, innovative techniques have been developed resulting in less invasive treatment procedures and, hence, overcoming serious side ...
Li Yan Y Centre for Epidemiological Studies and Clinical Trials and Center for Vascular Evaluations, Shanghai Key Lab of Hypertension, Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China, - - 2014
Hypertension is a major reversible risk factor for cardiovascular complications. According to recent guidelines, hypertension can be subdivided into isolated diastolic, isolated systolic, and systolic and diastolic mixed hypertension using proposed thresholds of various blood pressure components. In the present article, we reviewed the association of cardiovascular outcomes with diastolic ...
O'Callaghan Erin L EL School of Physiology & Pharmacology, University of Bristol, Bristol, BS8 1TD, - - 2014
Hypertension is a leading risk factor for the development of several cardiovascular diseases. As the global prevalence of hypertension increases, so too has the recognition of resistant hypertension. Whilst figures vary, the proportion of hypertensive patients that are resistant to multiple drug therapies have been reported to be as high ...
Fodor Ljiljana L aDepartment for Nephrology, Hypertension, Dialysis and Transplantation bDepartment for Diagnostic and Interventional Radiology, University Hospital Zagreb, School of Medicine, University of Zagreb, Zagreb, - - 2014
Arterial stiffness is an independent cardiovascular risk factor. Aging, high blood pressure and increased renin-angiotensin system activity contribute to increased arterial stiffness in patients with atherosclerotic renovascular hypertension (aRVH). A literature search failed to identify any study related to this topic. Therefore, our aim was to determine the arterial stiffness ...
Biaggioni Italo I Division of Clinical Pharmacology, Department of Medicine, and the Autonomic Dysfunction Center, 560 RRB, Vanderbilt University, Nashville, TN, 37232, USA, - - 2014
Orthostatic hypotension (OH) is defined as a sustained reduction of ≥20 mmHg systolic blood pressure or ≥10 mmHg diastolic blood pressure upon standing for ≤3 min. Orthostatic hypotension is commonly associated with hypertension, and its prevalence is highest in those with uncontrolled hypertension compared to those with controlled hypertension or normotensive community elderly ...
Aronow Herbert D HD Michigan Heart, 5325 Elliott Dr., Ste. #202, Ypsilanti, MI, 48197, USA, - - 2014
Device therapy for the treatment of uncontrolled and resistant hypertension has evolved significantly over the past several decades. Both renal artery disease and sympathetic hyperactivity have been linked to resistant hypertension. This manuscript will review the current evidence base supporting device therapy (e.g., renal artery revascularization, sympathetic nervous system modulation) ...
Qu En-Ze EZ Departments of Ultrasound (E.-Z.Q.) and Liver Transplantation (Y.-C.Z.), Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Department of Ultrasound, 302 Military Hospital of China, Beijing, China (Z.-Y.L., Y.L.); and Department of Ultrasound, Peking University Third Hospital, Beijing, China - - 2014
The clinical utility of contrast-enhanced sonography in portal hypertension remains unclear. We explored the feasibility of using contrast-enhanced sonography for noninvasive assessment of portal venous pressure. Twenty healthy individuals (control group; 9 men; mean age, 46.4 years) and 18 patients with portal hypertension (15 men; mean age, 46.2 years) were ...
Shimada Taro T Department of Gastroenterology and Nephrology, Chiba University Graduate School of Medicine, 1-8-1, Inohana, Chuou-ku, Chiba, 260-8670, - - 2014
The objective was to examine the effect of splenic circulation using a microbubble agent to assess the severity of portal hypertension. This prospective study consisted of 91 subjects (63.0 ± 12.6 years, 30-86; 60 males, 31 females), 62 cirrhosis and 29 controls, who underwent both Doppler ultrasound and contrast-enhanced ultrasound with a perflubutane ...
Sealy LaToya L LaToya Sealy, RN, FNP-BC, is a Practice Team Supervisor/Nurse Practitioner, ESPRIT Medical Care, Affiliate of the Visiting Nurse Service of New York, New York City, New York. Arthur Oliva, MSN, ANP-BC, is a Practice Team Supervisor/Nurse Practitioner, ESPRIT Medical Care, Affiliate of the Visiting Nurse Service of New York, New York City, New - - 2014
According to the Centers for Disease Control and Prevention (CDC), more than 65 million adults in America have hypertension (HTN) and fewer than half of those 65 million people have their blood pressure (BP) under control. More than 1,000 deaths occur each day related to HTN and Americans are at ...
Bangalore Ramachandra Abhay - - 2014
Vein maladaptation is a serious clinical problem in patients receiving coronary artery bypass grafts, renal dialysis arteriovenous fistulas, and related clinical procedures that subject veins to elevated blood flow and pressure. We propose a computational model of vein adaptation to altered pressure based on a constrained mixture theory of growth ...
Souza Eduardo Vieira de EV Faculty of Medicine, Federal University of Santa Catarina, Florianopolis, SC, - - 2014
To determine the behavior of intraocular pressure and its relationship with infusion pressure in vitrectomy, phacofragmentation and phacoemulsification surgeries in rabbits. Intraocular pressure fluctuation was measured in 24 eyes of 12 rabbits submitted to vitrectomy, phacofragmentation and phacoemulsification procedures (eight eyes per group). The procedures were divided according to the ...
Abraldes Juan G JG Cirrhosis Care Clinic, Liver Unit, Division of Gastroenterology, University of Alberta, Edmonton, Alberta T6E 4X8, Canada. Electronic address: - - 2014
Portal pressure is estimated through measuring the hepatic venous pressure gradient (HVPG). The main clinical applications of HVPG measurements include diagnosis, classification, and monitoring of portal hypertension, risk stratification, identification of candidates for liver resection, and monitoring efficacy of β-adrenergic blockers. Clinically significant portal hypertension is defined as an HVPG ...
Inami Takumi T Division of Cardiology, Second Department of Internal Medicine, Kyorin University School of Medicine, Tokyo, - - 2014
This study sought to prove the safety and effectiveness of pressure-wire-guided percutaneous transluminal pulmonary angioplasty (PTPA). PTPA has been demonstrated to be effective for treatment of chronic thromboembolic pulmonary hypertension. However, a major and occasionally fatal complication after PTPA is reperfusion pulmonary edema. To avoid this, we developed the PEPSI ...
Cuende J I JI Servicio de Medicina Interna, Complejo Asistencial Universitario de Palencia, Palencia, - - 2014
During 2013 and the first months of 2014, numerous studies have been published in the cardiovascular field. New guidelines have appeared for managing arterial hypertension and reducing cardiovascular risk by lowering cholesterol levels. New data have emerged on the considerable lipid-lowering efficacy of monoclonal antibodies against PCSK-9, in contrast, however, ...
Herrmann Joerg J Department of Medicine, Mayo Clinic, Rochester, MN. Electronic address: - - 2014
Heart failure is a dreaded complication of trastuzumab therapy in women with breast cancer overexpressing the human epidermal growth factor receptor (HER)-2. Experimental studies have pointed out that the HER-2 signaling pathway is important in the adaptation to high afterload conditions and its inactivation leads to cardiac decompensation. Herein, we ...
Zhao L-J LJ Department of Nephrology, and 1Department of Cardiology; West China Hospital, Sichuan University, Chengdu, Sichuan Province, China. - - 2014
Hemodialysis treatment has been revealed to increased the systolic pulmonary artery pressure (sPAP). Right ventricular dysfunction (RVD) had been demonstrated to predict mortality in chronic renal failure patients. We investigate the prevalence of pulmonary hypertension and RVD among patients and possible contributing factors for pulmonary hypertension. A cross-sectional survey consisted ...
Ladner Travis R TR Department of Neurosurgery, Vanderbilt University, Nashville, Tennessee, - - 2014
Aseptic cavernous sinus thrombosis (CST) is rare and may clinically masquerade as a carotid cavernous fistula. Conventional management includes oral anticoagulation, but cases of ocular hypertension affecting vision may require more aggressive intervention. We report a case of a woman with spontaneous bilaterally occluded cavernous sinuses with elevated intraocular pressure ...
Kim Jonathan H JH Division of Cardiology, Emory University, Atlanta, Georgia. Electronic address: - - 2014
Although hypertension is common in American-style football (ASF) players, the presence of concomitant vascular dysfunction has not been previously characterized. We sought to examine the impact of ASF participation on arterial stiffness and to compare metrics of arterial function between collegiate ASF participants and nonathletic collegiate controls. Newly matriculated collegiate ...
Bondonno Catherine P CP School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia; - - 2014
Endothelial nitric oxide (NO) is fundamental to cardiovascular health. Dietary nitrate and nitrate from endothelial derived NO metabolism provides a significant contribution to the circulating NO pool through the nitrate-nitrite-NO pathway. A critical step in this pathway is the reduction of nitrate to nitrite by the oral microbiota. We aimed ...
Yu Jin-Ming JM Institute of Clinical Epidemiology, Key Laboratory of Public Health Safety, Ministry of Education, School of Public Health, Fudan University, Shanghai, China. Electronic address: - - 2014
The prognostic significance of long-term visit-to-visit blood pressure variability (BPV) has not yet been validated in "real world" hypertensive patients. The aim of the current study is to explore the prognostic value of BPV on stroke in hypertensive patients. This was a dynamic prospective cohort study based on electronic medical ...
Abd Elaziz Khaled M KM Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Abbassia 11566, Cairo, - - 2014
Studies have shown alarming levels of hypertension among adults in the Middle East. The aim of our study is to measure the prevalence rate of hypertension among adults in Cairo (Egypt), identify possible risk factors for the development of hypertension and assess the rates of undiagnosed and uncontrolled hypertension. Cluster ...
Bruyne Pauline De - - 2014
Hypertension has been recognized as an important health issue in the pediatric population over the past years. This emphasizes the need for an organized and effective plan for diagnosis and management. This review provides information to guide physicians through a structured approach to (1) screen children for hypertension during routine ...
Wallbach Manuel M Department of Nephrology and Rheumatology, Georg-August-University Goettingen, - - 2014
Background/Aims: Resistant hypertension and chronic kidney disease (CKD) are interlinked via sympathetic overdrive. Baroreflex activation therapy (BAT) has been shown to chronically reduce blood pressure (BP) in patients with resistant hypertension. The effect of BAT on renal function in CKD patients with resistant hypertension has not been reported. The aim ...
Markus M R P MR Department Study of Health in Pomerania/Clinical-Epidemiological Research, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany. Electronic address: - - 2014
Hypertension and obesity are highly prevalent in Western societies. We investigated the associations of changes in body weight with changes in blood pressure and with incident hypertension, incident cardiovascular events, or incident normalization of blood pressure in patients who were hypertensive at baseline, over a 5-year period. Data of men ...
Faria Ana Paula Cabral de AP Faculdade de Ciências Médicas, Universidade Estadual de Campinas, São Paulo, SP, - - 2014
Resistant hypertension (RHTN) is a multifactorial disease characterized by blood pressure (BP) levels above goal (140/90 mmHg) in spite of the concurrent use of three or more antihypertensive drugs of different classes. Moreover, it is well known that RHTN subjects have high prevalence of left ventricular diastolic dysfunction (LVDD), which ...
Thomas Kevin L KL From the Department of Medicine, Duke University, Durham, NC (K.L.T., B.R.S., R.M., M.A., R.M.C., E.D.P.); Duke Clinical Research Institute, Durham, NC (K.L.T., B.R.S., K.D.T., N.M.A.L., S.C., L.T., R.M., M.A., R.M.C., E.D.P.); Healing with CAARE, Inc, Durham, NC (S. E.-B., K.D.); Duke Translational Medicine Institute, Durham, NC (R.M.C.); Department of Medicine, Ohio State University, Columbus, OH (K.B.). - - 2014
Although home blood pressure (BP) monitoring interventions have shown potential in selected populations, it is unclear whether such strategies can be generalized. We sought to determine whether a multifaceted BP control program that uses a web-based health portal (Heart360), community health coaches, and physician assistant guidance could improve hypertension control ...
Sharma Aman A Department of Internal Medicine, PGIMER, Chandigarh, - - 2014
A common ocular manifestation of sarcoidosis is anterior uveitis. Posterior uveitis is uncommon and optic disc edema is rare. We report one such case in which the initial presentation was mimicking malignant hypertension as the patient had a recent record of high blood pressure. However, the painful progressive vision loss ...
Barochiner Jessica J Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires , Buenos Aires , - - 2014
Abstract We aimed to determine a possible association between isolated morning hypertension (IMH) and meal-induced blood pressure (BP) fall in adult treated hypertensive patients who underwent home BP measurements. A total of 230 patients were included, median age 73.6, 65.2% women. After adjusting for age, sex, number of antihypertensive drugs, ...
Goessler Karla Fabiana KF Department of Physical Education, Physical Education and Sports Center, State University of Londrina , Londrina-PR , Brazil - - 2014
Abstract Purpose: This study aimed to analyze the hemodynamic and cardiac effects of direct renin inhibitor (DRI) treatment and swimming training in hypertensive rats. Methods: Seventy-seven rats were divide into eight groups: sedentary normotensive (SN), trained normotensive (TN), sedentary normotensive treated with DRI (SN_DRI), trained normotensive treated with DRI (TN_DRI), ...
Volpe Cristina C Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden; Department of Internal Medicine, Division of Endocrinology, Södersjukhuset, Stockholm, - - 2014
Primary aldosteronism (PA) is the most common cause of secondary hypertension with an estimated prevalence of 4.3% among hypertensive subjects in primary care and 9.5% in referral centres (1). PA is recognized to have specific deleterious effects on the cardiovascular system in addition to the negative effects of hypertension per ...
Zhang Lu L Centre for Epidemiological Studies and Clinical Trials, The Shanghai Institute of Hypertension, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, - - 2014
The present study aimed to evaluate the accuracy of the Rossmax CF175 upper-arm blood pressure monitor for home blood pressure monitoring according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were sequentially measured in 33 adult Chinese (17 women, mean age ...
Zhu Jun J Department of Urology, Tianjin Medical University General Hospital, Tianjin 300052, P.R. - - 2014
Previous studies have demonstrated that a natural product of celery seeds, 3‑n‑butylphthalide (NBP), has significant antihypertensive effects that are widely utilized in Chinese traditional medicine. The present study aimed to investigate the effects of NBP on hypertensive nephropathy, as well as the mechanisms underlying this disease in spontaneously hypertensive rats (SHRs). SHRs ...
Assunta Capozzella C University of Rome "Sapienza", Department of Anatomy, Histology, Medical-Legal and the Orthopedics, Unit of Occupational Medicine (Dir: Prof. F. Tomei), Viale Regina Elena 336, 00161 Rome, - - 2015
The aim of the present study is to evaluate whether workers in the sanitary fixtures industry are a category at risk of developing cardiovascular diseases, and in particular, whether chronic noise exposure may play a role in cardiovascular effects in exposed workers. Seventy-five employees engaged in sanitation fixtures production and ...
Doumas Michael M Michael Doumas, Antonios Lazaridis, 2 Propedeutic Department of Internal Medicine, Aristotle University, 54643 Thessaloniki, - - 2014
Hypertension is one of the most popular fields of research in modern medicine due to its high prevalence and its major impact on cardiovascular risk and consequently on global health. Indeed, about one third of individuals worldwide has hypertension and is under increased long-term risk of myocardial infarction, stroke or ...
Sun Jing Ping JP Division of Cardiology, S.H. Ho Cardiovascular and Stroke Centre, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, - - 2014
Cardiac synchronization is important in maintaining myocardial performance, but the mechanism of diastolic dyssynchrony leading to failing myocardium is unclear. We aim to study the relation of left ventricular (LV) diastolic dyssynchrony with diastolic dysfunction in patients with hypertension. Two-D, three-D and Doppler echocardiography were performed using the GE Vivid ...
Pimenta Adriano Marçal AM Department of Maternal and Child Nursing and Public Health, School of Nursing, Federal University of Minas Gerais, Av. Alfredo Balena, 190, CEP 30130-100, Belo Horizonte, Minas Gerais, Brazil. Electronic address: - - 2015
This study aimed to assess the relationship between perception of temperature inside the bus and hypertension among 1126 collective transportation workers in metropolitan region of Belo Horizonte, Brazil. Thermal discomfort was determined based on the perception of temperature inside the bus. Hypertension was determined if participant had a medical diagnosis ...
Clark Christopher E CE Primary Care Research Group Institute of Health Services Research University of Exeter Medical School Smeall Building St Luke's Campus Magdalen Rd Exeter Devon EX1 2LU.. - - 2014
Differences in blood pressure measurements between arms are commonly encountered in clinical practice. If such differences are not excluded they can delay the diagnosis of hypertension and can lead to poorer control of blood pressure levels. Differences in blood pressure measurements between arms are associated cross sectionally with other signs ...
Hocht Christian - - 2014
Blood pressure variability (BPV) is considered nowadays a novel risk factor for cardiovascular disease. Clinical evidences support that short-term and long-term BPV independently contribute to target organ damage, cardiovascular events and mortality in patients with hypertension or diabetes. Attenuation of excessive fluctuations of systolic and diastolic BPV has been suggested ...
Schillaci Giuseppe - - 2014
Elevated nighttime blood pressure (BP) and a reduced day-night BP fall ("nondipping" condition) are strong predictors of cardiovascular complications, both in hypertension and in the general population. A reduced or inverted nocturnal BP fall might also be theoretically used to define the most appropriate timing for drug administration. In a ...
Kinstry Brian Mc - - 2014
High blood pressure (BP) is an important risk factor for stroke and ischaemic heart disease. Yet, despite the availability of effective drugs, it is generally poorly controlled. Partly this is because some patients do not adhere to treatment regimens and partly because clinicians either measure BP insufficiently frequently or are ...
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