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Kjeldsen Sverre S Department of Cardiology, Faculty of Medicine, Oslo University Hospital Ullevaal, University of Oslo, 0450, Oslo, - - 2014
Despite the availability of effective pharmacological treatments to aid the control of blood pressure, the global rate of uncontrolled blood pressure remains high. As such, further measures are required to improve blood pressure control. Recently, several national and international guidelines for the management of hypertension have been published. These aim ...
Kostrzewska M M Department of Pulmonology, Allergology and Respiratory Oncology, University of Medical Sciences, 84. Szamarzewskiego St., Poznań, 60-569, Poland, - - 2014
In this study we determined the relationship between the severity of obstructive sleep apnea (OSA) and body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP), and carotid intima-media thickness (cIMT) in 30 hypertensive male patients, aged 30-70, with newly diagnosed OSA (15 with moderate OSA - Group A, ...
Takeshita Junko J Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia2Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, - - 2014
Hypertension is prevalent among patients with psoriasis. The effect of psoriasis and its severity on hypertension control is unknown. To determine the association between uncontrolled blood pressure and psoriasis, both overall and according to objectively measured psoriasis severity, among patients with diagnosed hypertension. Population-based cross-sectional study nested in a prospective ...
Lee Chung-Jen CJ Department of Nursing, Tzu Chi College of - - 2014
Aim: Arterial stiffness is recognized to be an independent risk factor for cardiovascular morbidity and mortality. Recent studies have found that osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to evaluate the relationship between the serum OPG level ...
Han Wei W Department of Internal Medicine, Hebei Medical University, No. 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei, People's Republic of - - 2014
To investigate whether inhibition of miR-29a functioning prevents the hypertension-induced ventricular hypertrophy and fibrosis. Patients diagnosed with hypertension and left ventricular hypertrophy were recruited for the study. Serum levels of miR-29a were determined by RT-PCR. Levels of serum matrix metalloproteinase-9 (MMP-9), collagen type I and III (PINP and PIIINP) were ...
Xu Tianyuan T Department of Urology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197, 2nd Ruijin Road, Shanghai, 200025, - - 2014
To evaluate the effect of adrenal surgery on blood pressure (BP) in patients with both nonfunctional adrenal adenoma (NFA) and hypertension and to assess factors affecting hypertension outcomes after surgery. Nonfunctional adrenal adenoma patients with hypertension who were treated with or without adrenal surgery at our center during 2005-2011 were ...
Nascimento Regina A RA Department of Pharmacology, Biosciences Institute of Botucatu, Sao Paulo State University - UNESP, Botucatu, Sao Paulo, - - 2014
Intoxication with Pb (lead) results in increased blood pressure by mechanisms involving matrix metalloproteinases (MMPs). Recent findings have revealed that MMP type two (MMP-2) seems to cleave vasoactive peptides. This study examined whether MMP-2 and MMP-9 levels/activity increase after acute intoxication with low lead concentrations and if these changes were ...
Rubio-Ruiz María Esther ME Department of Physiology, Instituto Nacional de Cardiología "Ignacio Chávez", México, - - 2014
Aging impairs blood vessel function and leads to cardiovascular disease. The mechanisms underlying the age-related endothelial, smooth muscle and extracellular matrix vascular dysfunction are discussed. Vascular dysfunction is caused by: 1) Oxidative stress enhancement. 2) Reduction of nitric oxide (NO) bioavailability, by diminished NO synthesis and/or augmented NO scavenging. 3) ...
Bento André Moreira - - 2014
Background: The hemodynamic effects of noninvasive ventilation with positive pressure in patients with pulmonary hypertension without left ventricular dysfunction are not clearly established. Objectives: Analyze the impact of increasing airway pressure with continuous positive airway pressure on hemodynamic parameters and, in particular, on cardiac output in patients with variable degrees ...
Tremblay-Gravel Maxime M Montreal Heart Institute and Université de Montréal, Montreal, Quebec, - - 2014
To investigate the association between baseline systolic blood pressure levels and mortality in patients with AF with or without LV dysfunction. Hypertension leads to cardiovascular disease but, in specific groups, low blood pressure has been associated with a paradoxical increase in mortality. In patients with AF and heart failure, the ...
Muskalla Anne M AM Division of Internal Medicine, University Hospital of Zurich, Zurich, - - 2014
G-protein receptor kinase 4 polymorphism influences blood pressure regulation via modulation of dopamine receptor D1 in renal proximal tubular cells. We investigated the role of G-protein receptor kinase 4 polymorphism in the response to hypertensive therapy in patients with essential hypertension. In a prospective study, we assessed the G-protein receptor ...
Zhu Jiaquan J 1Division of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, 2Division of Cardiovascular Surgery, Toronto General Hospital Department of Surgery, University of Toronto, Toronto, Canada 3Cardiothoracic Surgery Department of Xinhua Hospital, Shanghai Jiaotong University, Shanghai, - - 2014
The number of patients with the failing Fontan physiology is increasing. We tested a novel in-situ micro-axial pump (Impella) to support the failing atrio-pulmonary Fontan circulation in an acute pig model. A Fontan model was established in 8 juvenile pigs by connecting the right atrium to the main pulmonary artery ...
Kollias Anastasios A Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, University of Athens, Athens, - - 2014
In children, out-of-office blood pressure (BP) assessment (especially ambulatory monitoring) is regarded as indispensable for accurate hypertension diagnosis. This article reviewed the evidence on the association between out-of-office BP measurements and preclinical organ damage indices in children. A systematic review and meta-analysis of 93 relevant articles (1974-2012) was performed. Analysis ...
Park Hye Y HY aDepartment of Preventive Medicine, Seoul National University College of Medicine bDepartment of Environmental Health, Graduate School of Public Health, Seoul National University cEnvironmental Health Center, Seoul National University College of Medicine, Seoul dDepartment of Biochemistry eDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu fInstitute of Environmental Medicine, Seoul National University Medical Research Center, Seoul, Republic of - - 2014
Hypertension and vitamin D deficiency are prevalent worldwide, especially in the elderly. Considering the possibility of gene-environment contributions to disease development, we evaluated the influence of certain cytochrome P450 polymorphisms and vitamin D levels on blood pressure (BP). We measured serum 25-hydroxyvitamin D levels [25(OH)D] and BP in 535 individuals ...
Smith W W Hypertension in Africa Research Team (HART), North-West University, Potchefstroom, South - - 2014
Severe underweight may be a risk factor for hypertension in developing countries, although the manner whereby this occurs is unknown. Leptin is known to exert both beneficial and detrimental vascular effects, and is predictive of poor cardiovascular outcome at high levels, but also at low levels. We explored the relationship ...
Bebawy John F JF From the Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, - - 2014
Emergence hypertension after craniotomy is a well-documented phenomenon for which natural history is poorly understood. Most clinicians attribute this phenomenon to an acute and transient increase in catecholamine release, but other mechanisms such as neurogenic hypertension or activation of the renin-angiotensin-aldosterone system have also been proposed. In this open-label study, ...
Zullig Leah L LL Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC; Division of General Internal Medicine, Department of Medicine, Duke University, Durham, - - 2014
Hypertension is a common and costly disease among US veterans. The Veterans Affairs (VA) healthcare system is the largest integrated healthcare provider in the United States and reviewing hypertension interventions developed in the VA may inform interventions delivered in other integrated healthcare systems. This review describes behavioral interventions to improve ...
Poortvliet Rosalinde K E RK Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands; - - 2014
Visit-to-visit variability in blood pressure is an independent predictor of cardiovascular disease. This study investigates biological correlates of intra-individual variability in blood pressure in older persons. Nested observational study within the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) among 3,794 male and female participants (range 70-82 years) ...
Schulz Steffen S *Department of Medical Engineering and Biotechnology, University of Applied Sciences; and †Departments of Otorhinolaryngology and ‡Psychiatry and Psychotherapy, Jena University Hospital, Jena, - - 2014
To measure autonomic nervous system function after idiopathic sudden sensorineural hearing loss (ISSHL). Diagnostic prospective cohort single-center study. Tertiary referral university hospital. Twenty-three adult patients with ISSHL and 10 normal-hearing control patients without ISSHL (CON) matched with respect to age, sex, hypertension, and medication. Bivariate analysis of autonomic regulation (ISSHL ...
Páll Alida - - 2014
BackgroundSymptomatic paroxysmal hypertension without significantly elevated catecholamine concentrations and with no evidence of an underlying adrenal tumor is known as pseudopheochromocytoma.MethodsWe describe the case of a female patient with paroxysmal hypertensive crises accompanied by headache, vertigo, tachycardia, nausea and altered mental status. Previously, she was treated for a longer period ...
Goverwa Tafadzwa Priscilla - - 2014
More than half of hypertensive patients reviewed at Lupane District Hospital during the first half of 2011 had uncontrolled hypertension. This prompted an investigation on the prevalence of uncontrolled hypertension and associated factors among hypertensives on treatment. Analytical cross-sectional study was conducted. Three hundred fifty-four consenting participants were consecutively selected ...
Paulin Roxane R Medicine, University of - - 2014
Rationale: Right Ventricular Failure (RVF) is a major cause of morbidity and mortality in pulmonary hypertension (PHT), but its mechanism remains unknown. Myocyte enhancer factor 2 (Mef2) has been implicated in RV development, regulating metabolic, contractile and angiogenic genes. Moreover, Mef2 regulates microRNAs (miRNAs) that have emerged as important determinants ...
Fabbiano Salvatore S Centro de Investigación del Cáncer Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca, Campus Unamuno, 37007 Salamanca, - - 2014
Vascular smooth muscle cells (vSMCs) are key in the regulation of blood pressure and the engagement of vascular pathologies such as hypertension, arterial remodeling, and neointima formation. The role of the Rac1 GTPase in these cells remains poorly characterized. To clarify this issue, we have utilized genetically engineered mice to ...
Koo Brian B BB From the Department of Neurology, Yale University School of Medicine, New Haven, CT (B.B.K.); Department of Neurology, Connecticut Veterans Affairs Health System, West Haven (B.B.K.); Department of Biostatistics, University of Washington School of Public Health, Seattle (S.S.); Division of Sleep Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA (D.A.D., S.R.); and Department of Epidemiology, University of Minnesota, Minneapolis (P.L.L.). - - 2014
Periodic limb movements during sleep (PLMS) are associated with immediate increases in blood pressure. Both PLMS and hypertension have different distributions across racial/ethnic groups. We sought to determine whether PLMS is associated with hypertension among various racial/ethnic groups. A total of 1740 men and women underwent measurement of blood pressure ...
Hara Azusa A From the Studies Coordinating Centre, Research Unit Hypertension and Cardiovascular Epidemiology, KU Leuven Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium (A.H., L.T., Y.-M.G., L.J., Z.-Y.Z., Y.-P.L., J.A.S.); Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan (K.A.); Centre for Environmental Sciences, University of Hasselt, Hasselt, Belgium (T.S.N.); and Research and Development Group VitaK, Maastricht University, Maastricht, The Netherlands - - 2014
In view of the declining environmental lead exposure in the United States, we analyzed the National Health and Nutrition Examination Survey (2003-2010) for association of blood pressure and hypertension with blood lead. The 12 725 participants included 21.1% blacks, 20.5% Hispanics, 58.4% whites, and 48.7% women. Blacks compared with non-Blacks had ...
Vesoulis Zachary A ZA Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, - - 2014
Minoxidil is a potent antihypertensive used as an adjunctive agent in refractory hypertension. It exerts an antihypertensive effect through two mechanisms: selective arterial vasodilation by activation of potassium channels in the vascular smooth muscle and stimulation of carotid and aortic baroreceptors, leading to downstream release of renin and norepinephrine. Although ...
Johnsen Stein H SH Department of Neurology and Neurophysiology, University Hospital of North Norway, Tromsø, Norway; Department of Clinical Medicine, UiT - The Arctic University of Norway, Tromsø, - - 2014
The correlation between creatine kinase (CK) and blood pressure (BP) was examined prospectively in 120 patients with persistent high CK and 130 individuals with normal CK. Hypertension was defined as systolic BP (SBP) ≥140 mm Hg or diastolic BP (DBP) ≥90 mm Hg or current use of antihypertensive medication. Baseline CK was ...
Afridi H I HI 1] National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan [2] School of Mechanical and Manufacturing Engineering, Dublin City University, Dublin, - - 2014
Cigarette smoking causes an acute increase in blood pressure and heart rate and has been found to be associated with malignant hypertension (HT). A significant flux of toxic metals among other toxins reaches the lungs through smoking. In the present study, the relationship between essential (zinc and selenium) and toxic ...
Nielsen M L ML Cardiovascular and Metabolic Preventive Clinic, Department of Endocrinology, Centre for Individualized Medicine in Arterial Diseases (CIMA), Odense University Hospital, Odense, - - 2014
We conducted a 1:2 matched case-control study in order to evaluate whether the prevalence of coronary artery calcium (CAC) and electrocardiographic left ventricular hypertrophy (LVH) or strain was higher in patients with uncontrolled hypertension than in subjects from the general population, and evaluate the association between CAC and LVH in ...
Son Sang Joon SJ Department of Psychiatry, Ajou University School of Medicine, San 5, Wonchondong, Yeongtong-gu, Suwon 443-721, Republic of - - 2014
Although hypertension is known to be a risk factor for AD, the effects of hypertension on brain function in AD patients are not well understood. We investigated alterations in resting-state functional connectivity according to the presence of hypertension in AD patients by using a method of correlation analysis based on ...
Byrd James Brian JB Division of Cardiovascular Medicine, Department of Medicine, University of Michigan, 20-209 W, 2800 Plymouth Road, Ann Arbor, MI, 48109-2800, USA, - - 2014
In the USA, hypertension affects one in three adults, and anxiety disorders are the most commonly diagnosed mental health disorders. Both hypertension and anxiety have been studied extensively. Yet, a full understanding of anxiety's relationship to hypertension has been elusive. In this review, we discuss the spectrum of anxiety disorders. ...
Terracciano Antonio A aFlorida State University College of Medicine, Tallahassee, Florida bNational Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA cHospital San Raffaele Pisana IRCCS, Rome dIstituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche eUnità Operativa Complessa Cardiologia, Presidio Ospedaliero A. Businco, Cagliari, - - 2014
Anxiety and other psychological dispositions are thought to be associated with blood pressure. This study tests whether personality traits have long-term associations with masked and white-coat effects. A community-based sample of 2838 adults from Sardinia (Italy) completed the Revised NEO Personality Inventory, and 7 years later, blood pressure was assessed ...
Kalaycoğlu Ezgi E aDepartment of Cardiology, Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital, Trabzon bDepartment of Cardiology, Kocaeli Derince Education and Research Hospital, Kocaeli cDepartment of Cardiology, Gaziemir Nevvar Salih İşgören State Hospital, İzmir, - - 2014
This study was designed to investigate the effects of dipper and nondipper patterns on global longitudinal systolic functions of left ventricle (LV) by means of two-dimensional speckle tracking echocardiography in treated hypertensive diabetic patients with preserved left ventricular ejection fraction. We enrolled 86 hypertensive diabetic patients. Twenty-four hour ambulatory blood ...
Barmparas Galinos G From the Department of Surgery (G.B., D.Z.L., A.W.L., A.G., M.C., E.J.L.), Division of Acute Care Surgery and Surgical Critical Care, Cedars-Sinai Medical Center, Los Angeles, California; Department of Surgery (A.S.), Division of Acute Care Surgery and Surgical Critical Care, Brigham and Women's Hospital, Boston, Massachusetts; and Department of Surgery (M.B.), Division of Trauma Surgery and Surgical Critical Care, Delray Medical and Broward Health Medical Centers, Fort Lauderdale, - - 2014
The purpose of the current study was to investigate the effect of early adrenergic hyperactivity as manifested by prehospital (emergency medical service [EMS]) hypertension on outcomes of traumatic brain injury (TBI) patients and to develop a prognostic model of the presence of TBI based on EMS and admission (emergency department ...
Perez-Barcena Jon J Department of Neurology, University of Miami-Miller School of Medicine, 1120 Northwest 14th Street, Miami, FL 33136, USA. Electronic address: - - 2014
Intracranial pressure (ICP) monitoring is considered the standard of care in the majority of neurosurgical centers in North America and Europe. ICP is a reflection of the relationship between alterations in craniospinal volume and the ability of the craniospinal axis to accommodate added volume. ICP cannot be reliably estimated from ...
Zhang Caojin C Department of Cardiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences & Guangdong Cardiovascular Institute, Guangzhou, Guangdong 510100, - - 2014
While echocardiography has been a pivotal screening test in pulmonary arterial hypertension (PAH), the presence of structural cardiac defects may affect the ability to reliably predict pulmonary artery pressures (PAPs). This study sought to evaluate the accuracy of Doppler echocardiography (DE) for estimating PAPs in adult atrial septal defect (ASD) ...
Zhu Pengli P Department of Geriatric Medicine - - 2014
Abstract Apelin activity plays a role in regulating blood pressure. This study explored the relationship between single nucleotide polymorphisms (SNPs) in the Apelin gene (APLN) with hypertension and hypertension with central retinal artery equivalent (CRAE) stenosis in a coastal Chinese population. All subjects answered an epidemiological survey for demographic and ...
Lu Kai K Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University , Chongqing , PR China - - 2014
Abstract This study aimed to investigate the potential association between prevalence of hypertension and components of metabolic syndrome (MetS) in general population of North China. A cross-section survey was conducted from September to December 2013 in Kailuan community of a Northern China city, Tangshan. Anthropometric measurements, blood tests and questionnaire ...
Islam Shofiq S Department of Maxillofacial Surgery, Leicester Royal Infirmary, Leicester LE1 5WW, UK. Electronic address: - - 2014
Obstructive sleep apnoea (OSA) is associated with resistant hypertension. We investigated to what extent maxillomandibular advancement affected a patient's blood pressure postoperatively. We retrospectively analysed consecutive patients who had Bimaxillary advancement for OSA at our hospital following referral from the local sleep clinic. We collected relevant data on clinical characteristics ...
Han Qingyu Q Key Laboratory of High Efficiency and Clean Mechanical Manufacture, School of Mechanical Engineering, Shandong University, Jinan 250061, - - 2014
This study aims to assess the phase relationship of prefrontal tissue oxyhemoglobin oscillations using wavelet phase coherence analysis of cerebral Delta [HbO2] signals in cerebral infarction (CI) patients during the resting state. Continuous recordings of near-infrared spectroscopy signals were obtained from the left and right prefrontal lobes in 21 subjects ...
Espino Barros Palau Angelina A Department of Ophthalmology, Houston Methodist Hospital, Houston, - - 2014
To illustrate three different ophthalmic presentations of cryptococcal meningitis (CM). CM is the most common manifestation of extra-pulmonary cryptococcosis. Intracranial hypertension occurs in up to 75% of patients with CM and is associated with increased mortality. CM can present to the ophthalmologist as vision loss, papilledema, abducens palsy, and/or other ...
Si Dayong D *School of Life Science, Jilin University, Changchun, China; †Key-Lab for Evolution of Past Life and Environment in Northeast Asia, Ministry of Education, Jilin University, Changchun, China; ‡Division of Nephrology, The First Hospital of Jilin University, Changchun, China; and §Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, - - 2014
Marked interpatient variability exists in the blood pressure response to carvedilol, a nonselective β-blocker. Here we evaluated the influence of 4 common polymorphisms in genes of the β-adrenergic receptor on the antihypertensive efficacy of carvedilol in patients in a double-blinded monotherapy study. Eighty-seven subjects with uncomplicated essential hypertensive (49% men; ...
Fan Lei L Henan Provincial Center for Disease Control and Prevention, Institute of Health Education and Chronic Non-communication Disease Control Prevention, Zhengzhou, - - 2014
The present article aimed to explore and evaluate the epidemiology and determine the status of hypertension awareness, treatment and control in Henan province, China. Cross-sectional survey. Thirty counties in Henan province of China. There were 18 772 randomly selected 15-74 years old. The distribution of blood pressure and prevalence, awareness, treatment ...
Bowry Ritvij R University of Texas Health Sciences Center at - - 2014
Hypertension is a major modifiable risk factor for stroke, with an estimated 51% of stroke deaths being attributable to high systolic blood pressure globally.(1,2) The management of hypertension in stroke is determined by timing, the type of stroke, use of thrombolysis, concurrent medical conditions, and pharmacologic variables. We highlight the ...
Sheppard James P JP Nuffield Department of Primary Care Health Sciences, University of Oxford, - - 2014
Treatment for uncomplicated stage 1 hypertension is recommended in most international guidelines but there is little evidence to indicate that therapy is beneficial. To estimate the prevalence of this condition in an untreated population and the potential costs of initiating therapy in such patients. Cross-sectional study of anonymised patient records ...
Mohebbi Zinat Z Department of Nursing, School of Nursing, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, - - 2014
Tension and stress are among the factors that lead to hypertension. In most individuals, behavioral strategies, such as relaxation and massage, are effective in controlling the individuals' response to stress, thus reducing hypertension. This non-blind clinical trial was conducted on 90 patients with primary hypertension. The patients were randomly divided ...
Jones Shirley F SF Division of Pulmonary, Critical Care, and Sleep Medicine, Scott and White Healthcare, Texas A&M Health Science Center, Temple, - - 2014
While continuous positive airway pressure is the first-line treatment for obstructive sleep apnea, many patients find this form of therapy undesirable leading to treatment nonadherence. Both mandibular advancement devices and surgical therapy offer alternative solutions for such patients. This article serves to compare the types of surgical interventions and mandibular ...
Sparrow Kristen K Private Practice , San Francisco, - - 2014
Background: Heart rate variability (HRV), a noninvasive autonomic measure, has been applied to acupuncture interventions in controlled academic settings comparing points used, types of stimulation, or the HRV parameters measured. There is evidence that acupuncture decreases the stress response in both human and animal subjects, and can increase HRV in ...
O Hartaigh Bríain B Department of Radiology, Dalio Institute of Cardiovascular Imaging, NewYork-Presbyterian Hospital and the Weill Cornell Medical College, New York, NY; Department of Internal Medicine, Section of Geriatrics, Yale School of Medicine, Adler Geriatric Center, New Haven, - - 2014
The current study assessed which measure of heart rate (HR) is most associated with inflammatory activity. Among 368 hypertensive patients (mean age±standard deviation, 60.6±10.8; 52.9% women), mean daytime (from 6 am to 10 pm), nighttime (from 10 pm to 6 am), and 24-hour HR were recorded using a continuous 24-hour ...
Indra Tomáš T Third Department of Internal Medicine, General University Hospital, Prague, Czech Republic; and First Faculty of Medicine, Charles University, Prague, Czech Republic - - 2014
Primary aldosteronism (PA) represents the most common cause of secondary hypertension. Beyond increased blood pressure, additional harmful effects of aldosterone excess including inappropriate left ventricle (LV) hypertrophy were found. We evaluated the effect of adrenalectomy and spironolactone on blood pressure and myocardial remodelling in a long-term follow-up study. Thirty-one patients ...
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