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Results 251 - 300 of 2174
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López-Candales Angel - - 2013
The severity of pulmonary vascular resistance (PVR) is known to be a critical determinant of right ventricular (RV) systolic function; this relationship remains poorly characterized. We therefore, designed a study to examine the relationship that exists between echocardiographically measured PVR and maximal tricuspid annular plane systolic excursion (TAPSE) to gain ...
Mohamed Adel - - 2013
To determine the effect of vasopressin therapy on the efficacy of oxygenation and arterial pressure in infants with severe persistent pulmonary hypertension of the newborn. Retrospective case study. Neonatal ICU, Hospital for Sick Children, Toronto, Canada. Neonates with severe persistent pulmonary hypertension. Intravenous infusion of vasopressin. Ten infants satisfied the ...
Pratali Lorenza - - 2013
The aim of this study was to evaluate right ventricular (RV) and left ventricular function and pulmonary circulation in chronic mountain sickness (CMS) patients with rest and stress echocardiography compared with healthy high-altitude (HA) dwellers. CMS or Monge's disease is defined by excessive erythrocytosis (hemoglobin >21 g/dl in males, 19 ...
Karci Ayşe A Department of Anesthesiology and Reanimation, Medical School, Dokuz Eylul University, İzmir, Turkey. Electronic address: - - 2014
It is known that hypoxic pulmonary vasoconstriction increases as a result of intermittent regional hypoxic challenges. The aim of this study was to compare the effects of sevoflurane and propofol on oxygenation and shunt fraction during one-lung ventilation in a novel model of hypoxic preconditioning before one-lung ventilation. Sixteen Wistar-albino ...
Oliveira Rudolf K F - - 2013
Pulmonary arterial hypertension (PAH) is characterized by a pulmonary capillary wedge pressure (PCWP) of ≤15 mm Hg, given a normal left ventricular filling pressure (LVFP). However, recent studies have shown that, in PAH patients, diagnosis based on PCWP can erroneously classify a significant number of patients compared with diagnosis based ...
Ekkernkamp Emelie - - 2013
Abstract Background: High-intensity noninvasive positive pressure ventilation (HI-NPPV) is an effective treatment option in patients with stable hypercapnic chronic obstructive pulmonary disease (COPD). However, the effect of HI-NPPV compared with spontaneous breathing (SB) on minute ventilation (MV) in patients receiving long-term treatment remains to be determined. This study compared MV ...
Nalayanda Divya D DD Division Pediatric Surgery, Johns Hopkins Medical Institutions, Baltimore MD; Department of Biomedical Engineering, Johns Hopkins University, Baltimore - - 2014
The lungs of infants born with congenital diaphragmatic hernia suffer from immaturity as well as the short and long term consequences of ventilator-induced lung injury, including chronic lung disease. Antenatal and postnatal steroids are among current strategies promoted to treat premature lungs and limit long term morbidity. Although studied in ...
Naeije Robert - - 2013
The pulmonary circulation is a high-flow and low-pressure circuit. The functional state of the pulmonary circulation is defined by pulmonary vascular pressure-flow relationships conforming to distensible vessel models with a correction for hematocrit. The product of pulmonary arterial compliance and resistance is constant, but with a slight decrease as a ...
Ohad D G - - 2013
Canine pulmonary arterial hypertension (PAH) remains under-recognized and under-treated despite being prevalent. This retrospective study investigated whether selected historical and physical examination findings were associated with the diagnosis of canine PAH, defined as tricuspid regurgitation (TR) with a confirmed systolic pressure gradient ⩾35mmHg. Two hundred and one client-owned dogs (PAH ...
Groves Danja S - - 2013
Several strategies have been used to reduce the incidence of right ventricular failure after left ventricular assist device (LVAD) placement, including pulmonary vasodilation. The inhaled prostacyclin, epoprostenol, selectively dilates the pulmonary vasculature of ventilated areas of the lung, but also has been shown to inhibit platelet aggregation.(1) The authors evaluated ...
Salito Caterina - - 2013
The objective of this study was to evaluate to what extent lung compliance is affected by the individual and combined action of lung resection and hydrothorax in an animal model. Anaesthetized and mechanically ventilated rabbits (weight range 2÷2.2 kg) were randomized in two groups: (i) experimental hydrothorax (from 2 to ...
Kipping Valesca V Department of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Berlin - - - 2013
Purpose: Combination of prone positioning (PrP) and extracorporeal membrane oxygenation (ECMO) might be beneficial in severe acute respiratory distress syndrome (ARDS), because both approaches are recommended. However, PrP during ECMO might be associated with complications such as dislocation of ECMO cannulae. We investigated complications and change of oxygenation effects of ...
Chopra Amit - - 2013
DVT/PE/Pulmonary Hypertension PostersSESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PMPURPOSE: Conflicting data exist about the utility of diffusing capacity for carbon monoxide (DLCO) in prediction of severity/presence of pulmonary hypertension (PH). One reason for this might be that corrections for lung volume ...
Gustafson Joshua D - - 2013
Acute lung injury (ALI) is a condition that leads to impaired oxygen delivery. We demonstrated previously that using a portable oxygen concentrator (POC) with pulsed dose delivery of oxygen is an alternative option to conserve oxygen while still maintaining adequate oxygen delivery in a mechanical model. We hypothesized that using ...
Helmi M M Department of Intensive Care Adults, Erasmus MC, Rotterdam, the - - 2013
The last very-successful management of mechanical ventilation was in 2000 when application of low tidal volume and moderate pressure was introduced. It was then followed by the open- and baby-lung concept in order to open up the lung and keep the lung open. However, these strategies are followed with several ...
Khan Yasin - - 2013
Critical Care CasesSESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Sunday, October 27, 2013 at 07:30 AM - 08:30 AMINTRODUCTION: Neurally adjusted ventilatory assist (NAVA) is a mode of ventilation that coordinates the delivery of mechanical breaths and the level of inspiratory support with the neural respiratory drive as measured by ...
Hanson Josh - - 2013
Adults with severe malaria frequently require intravenous fluid therapy to restore their circulating volume. However, fluid must be delivered judiciously as both under- and over-hydration increase the risk of complications and, potentially, death. As most patients will be cared for in a resource-poor setting, management guidelines necessarily recommend that physical ...
Namendys-Silva Silvio - - 2013
Critical Care PostersSESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PMPURPOSE: The incidence of hypertension pulmonary (PH) in patients with acute respiratory distress syndrome (ARDS) is unknown.The purpose of this study was to describe the incidence and outcome of PH in patients with ...
Kamel Ghassan - - 2013
Cardiovascular Student/Resident Case Report Posters ISESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 29, 2013 at 01:30 PM - 02:30 PMINTRODUCTION: Porto-pulmonary hypertension is most commonly seen in patients with liver cirrhosis and the occurrence of porto-pulmonary hypertension in non-cirrhotic portal hypertension patients is rare [1].CASE PRESENTATION: The patient ...
Jaafarpour Molouk M MSc in Midwifery, Department of Midwifery, Nursing & Midwifery Faculty, Ilam University of Medical Science , Ilam, IR-Iran - - 2013
Negative Pressure Pulmonary O/Edema (NPPE) is potentially life-threatening and it is a general anaesthesia side effect. We are mentioning a rare case report of two brothers who were referred to our hospital for elective surgeries (varicocele and septoplasty) in a 3 years period. Both of them were athletes and their ...
Hussein Hussein - - 2013
Critical Care Student/Resident Case Report Posters IVSESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 29, 2013 at 01:30 PM - 02:30 PMINTRODUCTION: Stress-induced cardiomyopathy (SICM) is characterized by transient left ventricular wall motion abnormality associated with excessive catecholamine production. SICM occurring during the perioperative period has been reported (1). ...
Nandavaram Sravanthi - - 2013
Miscellaneous Student/Resident Case Report Posters IIISESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 29, 2013 at 01:30 PM - 02:30 PMINTRODUCTION: Respiratory insufficiency and failure due to bilateral diaphragmatic paralysis is usually seen in systemic conditions affecting the neural axis. However, Varicella Zoster causing isolated bilateral diaphragmatic paralysis is ...
Wrobel Jeremy - - 2013
Respiratory Support PostersSESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 30, 2013 at 01:30 PM - 02:30 PMPURPOSE: Intermittent positive airway pressure ventilation (IPPV) reduces right ventricular (RV) stroke volume in COPD. We aim to determine whether this reduction in RV stroke volume occurs via changes to RV preload and/or ...
Kirschbaum Andreas - - 2013
Lung metastases can be non-anatomically resected with a Nd:YAG Laser. It is recommended that the resected lung surface be sealed by slowly resorbable sutures. However, the lung tissue may be restricted by the sutures once it is re-ventilated. Thus, it was analysed whether the lung parenchyma is airtight after laser ...
Lan Chou-Chin - - 2013
Acute lung injury and acute respiratory distress syndrome (ALI/ARDS) cause substantial morbidity and mortality despite improvements in the understanding of lung injury and advances in treatment. Recruitment maneuver (RM) with high sustained airway pressures is proposed as an adjunct to mechanical ventilation to maintain alveolar patency. In addition, RM has ...
Kauppert Christoph A - - 2013
Pulmonary hypertension (PH) is considered a clinically important feature of Obesity-Hypoventilation Syndrome (OHS). We aimed to determine prevalence, characteristics and severity of PH including associations with clinical outcomes after established non-invasive positive pressure ventilation (NPPV). In a prospective cross-sectional study, clinically stable OHS-patients (NPPV duration ≥ 3 months) were consecutively assessed using ...
Davenport John - - 2013
Cetaceans are neckless, so the trachea is very short. The upper respiratory tract is separate from the mouth and pharynx. The dorsal blowhole connects, via the vestibular and nasopalatine cavities, directly to the larynx. Toothed cetaceans (Odontoceti) are capable of producing sounds at depth, either for locating prey, or for ...
Rain Silvia - - 2013
The role of right ventricular (RV) diastolic stiffness in pulmonary arterial hypertension (PAH) is not well-established. Therefore, we investigated the presence and possible underlying mechanisms of RV diastolic stiffness in PAH-patients. Single-beat RV pressure-volume analyses were performed in 21 PAH-patients and 7 controls to study RV diastolic stiffness. Data presented ...
Biais Matthieu - - 2013
Infrarenal aortic cross-clamping (ACC) induces hemodynamic disturbances that may affect respiratory-induced variations in stroke volume and, therefore, affect the ability of dynamic parameters such as pulse-pressure variation (PPV) to predict fluid responsiveness. Since this issue has not been investigated yet to authors' knowledge, the hypothesis was tested that ACC may ...
Corley Amanda - - 2013
Airway suctioning in mechanically ventilated patients is required to maintain airway patency. Closed suction catheters (CSC) minimise lung volume loss during suctioning but require cleaning post-suction. Despite their widespread use, there is no published evidence examining lung volumes during CSC cleaning. The study objectives were to quantify lung volume changes ...
Yu Lan - - 2013
Abstract The osmotic pressure of xylitol solution at a wide concentration range was calculated according to the UNIFAC model and experimentally determined by our newly reported air humidity osmometry. The measurements from air humidity osmometry were compared with UNIFAC model calculations from dilute to saturated solution. Results indicate that air ...
Guihaire Julien - - 2013
The right ventricle (RV) faces major changes in loading conditions associated with cardiovascular and pulmonary vascular disorders. Despite major pharmacological advances since the last decade, pulmonary arterial hypertension remains a deadly disease mainly secondary to the development of right ventricular failure (RVF). Several experimental models of RVF have been developed ...
Finkelhor Robert S - - 2013
Although the echo Doppler (D) estimation of pulmonary artery systolic pressure (PASP) was initially highly correlated with right heart catheterization (RHC), recent D-RHC studies have questioned its accuracy. The aim of this study was to reevaluate this relationship and to determine possible explanations for disparate D-RHC results. We retrospectively identified ...
Wang Xiaoguang - - 2013
New methods for perfluorocarbon (PFC) application have been proposed which include aerosolization and vaporization. However, the experimental documentation of efficacy of vaporization of PFC in the treatment of acute respiratory distress syndrome (ARDS) is still lacking. This study aims to examine the effects of vaporized PFC on gas exchange and ...
Main Michael L - - 2013
Ultrasound contrast agent safety has received recent attention based on reports of associated serious adverse events. The US Food and Drug Administration requested this postmarketing study of the effects of Optison on pulmonary hemodynamics. The aim of this study was to compare Optison and a placebo for effects on pulmonary ...
Gattinoni Luciano - - 2013
In patients with acute respiratory distress syndrome (ARDS), in supine position, there is a decrease of inflation along the sternum vertebral axis, up to lung collapse. In 1991 we published a report showing that, in ARDS patients, shifting from supine to prone position led immediately to the inversion of the ...
Hooper Stuart B - - 2013
The transition to newborn life critically depends upon lung aeration and the onset of air-breathing, which triggers major cardiovascular changes required for postnatal life, including increases in pulmonary blood flow. Recent imaging studies indicate that lung aeration and functional residual capacity (FRC) recruitment results from inspiratory efforts, which create transpulmonary ...
Emr Bryanna - - 2013
IMPORTANCE Up to 25% of patients with normal lungs develop acute lung injury (ALI) secondary to mechanical ventilation, with 60% to 80% progressing to acute respiratory distress syndrome (ARDS). Once established, ARDS is treated with mechanical ventilation that can paradoxically elevate mortality. A ventilation strategy that reduces the incidence of ...
Sawatdee Somchai - - 2013
Sildenafil citrate is a selective phosphodiesterase-5 inhibitor used for the treatment of erectile dysfunction and pulmonary hypertension. The delivery of sildenafil directly to the lung could have several advantages over conventional treatments for pulmonary hypertension because of the local delivery, a more rapid onset of response, and reduced side effects. ...
Bermejo Silvia - - 2013
Almitrine enhances hypoxic pulmonary vasoconstriction (HPV) and can improve hypoxemia related to one-lung ventilation (OLV). Studies using almitrine have been conducted without inhaled anesthetics because they could inhibit HPV, counteracting the effect of almitrine. This hypothesis, however, has not been confirmed. This study's aim was to evaluate whether almitrine could ...
Lampland Andrea L - - 2013
Surfactant therapy may be beneficial in acute lung injury (ALI). In spontaneously breathing newborn pigs with ALI supported with continuous positive airway pressure (CPAP), we evaluated the hypothesis that aerosolized KL4 surfactant (AERO KL4 S) would provide a similar therapeutic effect as intratracheal KL4 surfactant (ETT KL4 S) when compared ...
Maccari Juçara Gasparetto - - 2013
There have been few reports of factors affecting aerosol delivery during noninvasive ventilation (NIV). Nebulization is a standard practice and our objective was to determine the effect of spontaneous breathing and NIV mode on 99m-Technetium (Tc) lung deposition in subjects with normal lung. Thirteen healthcare volunteers were submitted to a ...
Bruells Christian S - - 2013
Mechanical ventilation is a life-saving intervention for patients with respiratory failure. Unfortunately, a major complication associated with prolonged mechanical ventilation is ventilator-induced diaphragmatic atrophy and contractile dysfunction, termed ventilator-induced diaphragmatic dysfunction (VIDD). Emerging evidence suggests that positive pressure ventilation (PPV) promotes lung damage (ventilator-induced lung injury [VILI]), resulting in the ...
Jin Yanwu - - 2013
This study compared the effects of sevoflurane and propofol on the inflammatory response and pulmonary function of patients with lung cancer during the perioperative period. Forty patients who underwent a selective resection of the inferior lobe of the left lung were randomly divided into two groups, with one group anesthetized ...
Yang Yi - - 2013
Intra-abdominal hypertension (IAH) is common in acute respiratory distress syndrome (ARDS) patients and when resulting in decrease of chest wall compliance will weaken the effect of positive end expiratory pressure (PEEP). We investigated the effect of PEEP titrated by transpulmonary pressure (Ptp) on oxygenation and respiratory mechanics in ARDS patients ...
Amigoni Maria - - 2013
Mechanical ventilation is necessary during acute respiratory distress syndrome, but it promotes lung injury because of the excessive stretch applied to the aerated parenchyma. The authors' hypothesis was that after a regional lung injury, the noxious effect of mechanical ventilation on the remaining aerated parenchyma would be more pronounced. Mice, ...
Roy Shreyas K SK Department of Surgery, Upstate Medical University, Syracuse, NY 13210, - - 2013
Once established, the acute respiratory distress syndrome (ARDS) is highly resistant to treatment and retains a high mortality. We hypothesized that preemptive application of airway pressure release ventilation (APRV) in a rat model of trauma/hemorrhagic shock (T/HS) would prevent ARDS. Rats were anesthetized, instrumented for hemodynamic monitoring, subjected to T/HS, ...
Linnarsson Dag - - 2013
Lung diffusing capacity for NO (DLNO) was determined in eight subjects at ambient pressures of 505, 1,015, and 4,053 hPa (379, 761 and 3,040mmHg) as they breathed normoxic gases. Mean values were 116.9+- 11.1 (SEM), 113.4+- 11.1 and 99.3+- 10.1 ml min-1 hPa-1 at 505, 1,015, and 4,053 hPa, with ...
van Gestel Arnoldus J R - - 2013
Chronic obstructive pulmonary disease (COPD) has been associated with increased risk for cardiovascular disease but mechanisms underlying this association are incompletely understood. The speed of beat-to-beat changes in systolic blood pressure (vSBP) was found to be pronounced in patients with elevated cardiovascular risk. Although increased vSBP may thus be a ...
Stratta C - - 2013
Portopulmonary hypertension has been reported in 2% to 9% of candidates for liver transplantation (OLT). If it is moderate to severe, it represents a contraindication to the procedure until pulmonary vasodilatative therapy has been optimized. We report the case of a 43-year-old man, scheduled for OLT due to alcoholic cirrhosis ...
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