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Mukerji Amit - - 2012
Background: Noninvasive ventilation has been used increasingly in recent years to minimize the duration of endotracheal mechanical ventilation in neonates due to its association with lung injury. Nasal high-frequency oscillation (nHFO) is a relatively new noninvasive modality but evidence for its use is limited. Objective: The goal of this study ...
Luo Jiaying - - 2012
SUMMARY AT A GLANCE: Two titration methods have been used to assess the pressure for long term CPAP treatment. We compared automatic titration with manual titration, the gold standard for determining CPAP pressure, and found that the pressure from automatic titration is consistently higher than the pressure derived from manual ...
Zang Hong-Rui - - 2012
The role of nasal obstruction in the pathogenesis of obstructive sleep apnea/hypopnea syndrome (OSAHS) has been debated for decades. In this prospective study, we compared the pharyngeal aerodynamic characteristics of OSAHS patients and normal people, and investigated the contribution of total nasal airway resistance to the pathophysiology of OSAHS. Computational ...
Bhandari Vineet - - 2012
Multiple randomized controlled trials have suggested that nasal intermittent positive pressure ventilation, compared with nasal continuous airway pressure, prevents extubation failure and may decrease bronchopulmonary dysplasia. This article summarizes these studies and suggests strategies for the use of nasal intermittent positive pressure ventilation in neonates.
Rocha G - - 2012
Objective:To identify variables associated with early nasal continuous positive airway pressure (ENCPAP) failure in preterm neonates less than 30 weeks gestational age.Study Design:Multicenter prospective study including 131 preterm newborns, over a period of 2 years. Patients and respiratory variables were assessed using univariate analysis.Result:Variables associated with ENCPAP failure were: the ...
Bozza P - - 2012
PURPOSE: The best anesthesia for newborns/infants necessitating colorectal surgery remains questionable. Endovenous and locoregional anesthesiological approaches were compared to determine the influence on stress response. METHODS: Patients with anorectal malformations or Hirschsprung's disease were randomized to inhalatory/epidural anesthesia (IPA) or inhalatory/endovenous anesthesia (IEA). Heart rate, blood pressure, oxygen saturation, serum ...
Kanai Rie - - 2012
Abstract Conclusion: Negative middle ear pressure was observed in many patients and otitis media with effusion (OME) developed in 3.3% of ears after surgery under general anesthesia. Gas dynamics in the middle ear cavity induced by nitrous oxide inhalation anesthesia and transient blockage of the eustachian tube induced by surgery ...
Mazaheri-Khameneh Ramin - - 2012
Objective-To compare time to loss of consciousness (LOC) and effective maintenance of anesthesia following intraosseous (IO) and IV administration of propofol in rabbits. Design-Evaluation study. Animals-24 New Zealand White rabbits. Procedures-Rabbits were selected to receive IO (n = 6) or IV (6) bolus administration of 1% propofol (12.5 mg/kg [5.67 ...
Yamamoto Eiji - - 2012
Effects of general anesthesia can be controllable by the ambient pressure. We perform molecular dynamics simulations for a 1-palmitoyl-2-oleoyl phosphatidylethanolamine lipid bilayer with or without xenon molecules by changing the pressure to elucidate the mechanism of the pressure reversal of general anesthesia. According to diffusive nature of xenon molecules in ...
Derikx Roy L E - - 2012
ABSTRACT: Electroconvulsive therapy (ECT) is thought to raise intracranial pressure (ICP) after an increase of blood pressure. In depressed patients (n = 17) treated with ECT, using transcranial Doppler, pulsatility index (PI; as indicator of ICP) and blood pressures were prospectively measured. The highest PI was measured just after anesthesia ...
Langdon Fielding C - - 2012
Changes in arterial pressure due to respiratory phases have been used to predict fluid responsiveness in a number of species and pulse pressure variation (PPV) and systolic pressure variation (SPV) are commonly used. The relationship between PPV and SPV has not been described in horses. To describe and compare PPV ...
Hess L - - 2012
Background  Ephedrine is used in treatment of hypotension during anesthesia. We investigated its effects on the psychomotor recovery and its potential adverse reactions on cardiorespiratory functions in rhesus monkeys. Methods  The monkeys received 50 μg/kg medetomidine, 2.0 mg/kg S-ketamine with 150 IU hyaluronidase i.m. Pulse rate, blood pressure and saturation of haemoglobin were ...
Erken Haydar Ali - - 2012
Inconsistency in consecutive blood pressure values is one of the most frequently observed problems in tail cuff method. The aim of this study was to measure blood pressure using the tail cuff method in rats without heating, anesthesia, and movement restriction. In this study, it has been shown that blood ...
O'Neill Daniel K - - 2012
ABSTRACT: Heel ulcers are clinically challenging. Limited subcutaneous tissue covering the calcaneus bone makes the heel vulnerable to pressure injury. Adequate debridement of fibrotic, infected, and necrotic tissue is essential for healing. The authors report a standardized anesthesia protocol using regional anesthesia with sedation rather than general anesthesia for heel ...
Radke Oliver C - - 2012
BACKGROUND:: Positive-pressure ventilation causes a ventral redistribution of ventilation. Spontaneous breathing during general anesthesia with a laryngeal mask airway could prevent this redistribution of ventilation. We hypothesize that, compared with pressure-controlled ventilation, spontaneous breathing and pressure support ventilation reduce the extent of the redistribution of ventilation as detected by electrical ...
Hedenstierna G - - 2012
Anesthesia is safe in most patients. However, anesthetics reduce functional residual capacity (FRC) and promote airway closure. Oxygen is breathed during the induction of anesthesia, and increased concentration of oxygen (O(2) ) is given during the surgery to reduce the risk of hypoxemia. However, oxygen is rapidly adsorbed behind closed ...
Hwang J W - - 2012
BACKGROUND: Maternal hypotension occurs commonly during cesarean delivery under spinal anesthesia. We evaluated whether hypotension due to aortocaval compression could be prevented by maintaining a lateral position after an intrathecal injection. METHODS: Eighty-six women undergoing elective cesarean delivery were enrolled. Spinal anesthesia was conducted in the right lateral position using ...
Fulambarker Ashok - - 2012
Yoga is adjunctively utilized outside the United States in the treatment of a variety of diseases, including chronic obstructive pulmonary disease (COPD), but there are no studies assessing its adjunctive efficacy in the United States. We prospectively evaluated the effects of yoga training on the quality of life (QOL) and ...
Gulsoy Kemal K Anaesthesia and Reanimation Department, Ankara Numune Training and Research Hospital, Altindag, Ankara, - - 2012
To compare the effect of dexmedetomidine and fentanyl on hemodynamic changes in chronic male smokers. This is a prospective, randomized, blinded study. Were selected 60 chronic male smokers (aged 16 to 60 years). The patients were randomly divided into two groups: Group D (n=30) received 1μg.kg(-1) dexmedetomidine and Group F ...
Nair Jayasree - - 2012
We report a case study of a term neonate presenting with oxygen desaturation without respiratory distress or acidosis, despite receiving 100% oxygen through a nasal cannula. Echocardiogram showed evidence of persistent pulmonary hypertension of the newborn (PPHN). She was successfully treated with inhaled nitric oxide (iNO) via nasal cannula without ...
Boback Scott M - - 2012
Many species of snakes use constriction-the act of applying pressure via loops of their trunk-to subdue and kill their prey. Constriction is costly and snakes must therefore constrict their prey just long enough to ensure death. However, it remains unknown how snakes determine when their prey is dead. Here, we ...
Hockel Konstantin - - 2012
Anesthesia is indispensable for in vivo research but has the intrinsic potential to alter study results. The aim of the current study was to investigate the impact of three common anesthesia protocols on physiological parameters and outcome following the most common experimental model for subarachnoid hemorrhage (SAH), endovascular perforation. Sprague-Dawley ...
Koga Seiji - - 2012
Objective Abnormal left ventricular (LV) geometry, especially concentric hypertrophy, is associated with cardiovascular morbidity and mortality. The aim of this study was to evaluate the impact of obstructive sleep apnea syndrome (OSAS) and the effects of nasal continuous positive airway pressure (CPAP) on the LV geometric patterns. Methods The LV ...
Yi Yong - - 2012
To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque. The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training. Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVet® rebound ...
Jung Jun-Young - - 2012
Prolonged tourniquet inflation produces a hyperdynamic cardiovascular response. We investigated the effect of continuous remifentanil infusion on systemic arterial pressure, heart rate, and cardiac output changes during prolonged tourniquet use in elderly patients under sevoflurane/N(2)O general anesthesia. Thirty female patients scheduled for knee replacement arthroplasty were infused with either remifentanil ...
Jiang Hai - - 2011
Difficult airway remains not only a challenge to the anesthesiologists, but also a life-threatening event to the patients. Awake intubation is the principal choice to deal with difficult airway, and a key point for awake intubation is airway topical anesthesia. Yet, so far there is no ideal topical anesthesia approach ...
Searl Jeff - - 2013
Objectives : (1) To compare oral pressure and nasal airflow in 3- to 5-year-olds versus older children and adults; (2) to describe stability of these measures in 3- to 5-year-olds at two recording times; and (3) to report participation rates of 3- to 5-year-olds for the aerodynamic protocol. Design : ...
Liu Shan - - 2011
1. Cardiorenal syndrome (CRS) describes the primary dysfunction in either the kidney or heart that initiates the combined impairments of both organs. The heart and the kidney exert reciprocal control of the respective function to maintain constant blood volume and organ perfusion under continuously changing conditions. 2. The pathophysiology of CRS is ...
Evangelista Janaina S A M - - 2011
Crotalus durissus cascavella is a snake native of northeastern Brazil. The aim of the study was to investigate the effects of C. d. cascavella venom on rat mean arterial pressure and vascular reactivity in the mesenteric vascular bed. The venom evoked a dose-dependent decrease in mean arterial pressure, cardiac and ...
Kim Eui Joo - - 2010
Portopulmonary hypertension is a complication of chronic liver disease, which has significant effects on survival and prognosis. Although the pathogenesis of pulmonary arterial hypertension has been well known, portopulmonary hypertension is often underestimated in patients with chronic liver disease. Every clinician who manages patients with chronic liver disease complaining of ...
Giuliodori Mauricio J - - 2010
We developed a model to demonstrate how a hopping kangaroo breathes. Interestingly, a kangaroo uses less energy to breathe while hopping than while standing still. This occurs, in part, because rather than using muscle power to move air into and out of the lungs, air is pulled into (inspiration) and ...
Tantucci Claudio - - 2011
Background. The presence and extent of tidal airway closure is not routinely assessed in asthma. The objective of this study was to provide a simple functional tool able to detect tidal airway closure during bronchoconstriction in asthma. Methods. In 20 subjects with mild persistent asthma, we sequentially performed the measurement ...
Elliott Judy - - 2010
This article outlines the actions taken by one acute trust to implement evidence-based, best practice recommendations for pressure ulcer prevention. Initially, an exploratory study identified specific areas for practice development, particularly improving early risk assessment, intervention and focus on heel ulcers. Further actions included recruiting tissue viability support workers to ...
Striegl Amanda M - - 2011
The mechanical in-exsufflator (MIE) is commonly used to augment cough in patients with neuromuscular disease from infancy to adulthood. Little is known about the alveolar pressures, lung volumes, and expiratory flow rates generated by the MIE when used via tracheostomy tube in infants and children. A high-fidelity mechanical lung model ...
Butler Jane E - - 2011
. Spinal cord injury (SCI) patients have respiratory complications because of abdominal muscle weakness and paralysis, which impair the ability to cough. . This study aims to enhance cough in high-level SCI subjects (n = 11, SCI at or above T6) using surface electrical stimulation of the abdominal muscles via ...
Baydur Ahmet - - 2010
BACKGROUND: The impact on respiratory function of gunshot injuries to the chest is unknown. The objective is to assess pulmonary function and respiratory muscle strength (RMS) in patients who have recently sustained an isolated gunshot injury to the chest. METHODS: After institutional review board approval, patients with isolated gunshot injuries ...
Mitchell G - - 2011
We have measured lung mass and trachea dimensions in 46 giraffes of both genders ranging in body mass from 147 kg to 1441 kg, calculated static and dynamic lung volumes, and developed allometric equations that relate changes in them to growth. We found that relative lung mass is 0.6±0.2% of ...
Moore Alastair J - - 2010
Hyperinflation is a recognized adverse prognostic factor in COPD. As the sniff inspiratory nasal pressure (SnIP) principally reflects the severity of hyperinflation in COPD, we hypothesized that it might also be a predictor of mortality. We therefore compared the SnIP to the inspiratory capacity-to-total lung capacity (IC/TLC) ratio as predictors ...
Brunelli Alessandro - - 2011
Background: The objective of this prospective observational study was to evaluate the association between the airflow and intrapleural pressures digitally recorded during the immediate postoperative period after lobectomy and their ability to predict the risk of subsequent prolonged air leak (PAL). Methods: A total of 145 consecutive patients underwent pulmonary ...
Banzatto Melissa Guerato Pires - - 2010
The aim of this paper is to study the respiratory muscle strength by evaluating the maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP) and lung volume before and 3 and 6 months after adenotonsillectomy. This is an interventional, before and after trial. It was set at the Department of Otolaryngology, ...
Baldi Simonetta - - 2010
The effects of full lung inflation on respiratory conductance (Grs) and reactance (Xrs) were measured in 15 subjects with moderate to severe chronic obstructive pulmonary disease (COPD) and 11 matched healthy control subjects. Airway distensibility was estimated from the ratio of the difference of Grs between functional residual capacity and ...
Tanaka Kunihiko - - 2010
INTRODUCTION: In space, mobility of the current extravehicular activity space suit is limited due to the pressure differential between the inside and outside of the suit. We have previously demonstrated that an elastic glove increased mobility when compared with a non-elastic glove such as that found in the current suit. ...
Squier Samuel B - - 2010
The relationship between changes in absolute end-expiratory lung volume (EELV) and collapsibility has not been rigorously quantified. We hypothesized that pharyngeal collapsibility varies inversely with absolute lung volume in sleeping humans during 1) conventional and 2) isovolume measurements of passive critical pressure (Pcrit). Eighteen healthy subjects (11 male, 7 female) ...
Kondo Tetsuri - - 2010
We obtained flow-volume (F-V) curves in anesthetized rats by applying positive pressure on the body surface. To obtain the best curve, tracheal intubation with either a 12 or 13 gauge catheter and a surface pressure greater than 56 cmH(2)O was necessary. Peak expiratory flow rate (PEFR) and forced vital capacity ...
Patroniti Nicol? - - 2010
OBJECTIVE: It is commonly assumed that lung volume at zero end-expiratory pressure (functional residual capacity) is not affected by positive end-expiratory pressure (PEEP) even in presence of alveolar recruitment, and it is often ignored when measuring lung recruitment by pressure-volume curves. Aim of the study was to investigate the effect ...
Heinze Hermann - - 2010
BACKGROUND: Measurement of functional residual capacity (FRC) is now possible at bedside, during mechanical ventilation. OBJECTIVES: To determine the relationship of measured absolute and relative predicted FRC values to oxygenation and respiratory-system compliance, and to identify variables that influence FRC in ventilated patients after cardiac surgery. METHODS: We retrospectively analyzed ...
Gunda Chandrakala P - - 2010
Hypotensive episodes are a common complication of spinal anesthesia during Cesarean section. The purpose of this study was to compare the effectiveness and the side effects of vasopressors, ephedrine and phenylephrine, administered for hypotension during elective Cesarean section under spinal anesthesia. The study consisted of 100 selected ASA I/II females ...
Almeida Sara Regina Meira - - 2010
OBJECTIVE: To verify how efficient respiratory parameters are in the follow-up of subjects with amyotrophic lateral sclerosis (ALS) and to observe possible correlations between respiratory and nutritional functions. METHOD: Sixteen patients with probable or defined ALS were selected and evaluated over eight months using the following respiratory parameters: spirometry, maximum ...
Antonaglia Vittorio - - 2010
The results of the studies on pulmonary gas distribution during constant-flow controlled-volume inflation (VCV) and inspiratory constant pressure inflation (PCV) in experimental studies are conflicting. In a mathematical model, with the characteristics of two lung compartments including tissue viscoelastic properties, pulmonary gas distribution was tested by simulating PCV and VCV ...
Wellman Tyler J - - 2010
Regional specific lung volume change (sVol), defined as the regional tidal volume divided by the regional end-expiratory gas volume, is a key variable in lung mechanics and in the pathogenesis of ventilator-induced lung injury. Despite the usefulness of PET to study regional lung function, there is no established method to ...
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