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Moran F F University of Ulster, Newtownabbey, Northern Ireland. - - 2010
Respiratory muscle strength is used diagnostically in clinical practice and as an outcome measure in clinical trials in various chronic lung diseases. There is limited data on its repeatability in people with non-CF bronchiectasis. The aim of the present study was to assess the repeatability of maximal inspiratory (P( I)max) ...
Dzamonja Gordan - - 2010
Apnea divers increase intrathoracic pressure voluntarily by taking a deep breath followed by glossopharyngeal insufflation. Because apnea divers sometimes experience hypotension and syncope during the maneuver, they may serve as a model to study the mechanisms of syncope. We recorded changes in hemodynamics and sympathetic vasomotor tone with microneurography during ...
Toumpanakis Dimitris - - 2010
Resistive breathing is associated with large negative intrathoracic pressures. Increased mechanical stress induces high-permeability pulmonary edema and lung inflammation. To determine the effects of resistive breathing on the healthy lung. Anesthetized rats breathed through a two-way nonrebreathing valve. The inspiratory line was connected to a resistance setting peak inspiratory tracheal ...
Anand Ashima - - 2010
Using a physiological model of acutely increasing venous return into the lungs, i.e. by applying and then releasing lower body negative pressure (LBNP) to mimic the natural stimulus of juxtapulmonary capillary (J) or pulmonary C fibre receptors, produced an immediate and significant reduction in the amplitude of the Hoffman (H) ...
Ross Patrick A - - 2010
There are limited validated, objective, and minimally invasive techniques for the bedside evaluation of upper airway obstruction (UAO) in sick infants, despite its frequency in pediatric medicine. Prior techniques include pressure-rate product (PRP), a product of esophageal pressure and respiratory rate and phase angles (PAs), a measure of asynchrony between ...
LaRosa Christopher - - 2010
The diagnosis of hypertension in children relies upon blood pressure distribution tables adjusted for gender, age, and height. Unlike in adults, specific blood pressure levels corresponding to long-term adverse outcomes in children have not been established. However, there are known surrogate markers of target organ injury associated with elevated blood ...
Murata Shinya - - 2010
BACKGROUND: The rise in inspiratory flow is important during patient-triggered ventilation. Many ventilators incorporate a function to control the time to reach the targeted airway pressure (inspiratory rise time). However, it has not been clarified how inspiratory rise time affects inspiratory work load under various ventilator settings. In a bench ...
Seikaly Mouin G - - 2010
Over the past two decades the attitudes of pediatric health care providers towards childhood hypertension, as a predictor of future development of hypertension in adults have undergone considerable conceptual change. Childhood hypertension has unique features that differentiate it from hypertension in adults. It is widely accepted that pediatric hypertension carries ...
Nilsson Lena - - 2010
Recent studies using photoplethysmographic (PPG) signals from pulse oximeters have shown potential to assess hypovolaemia during spontaneous breathing. This signal is heavily filtered and reports are based on respiratory variations in the small pulse synchronous variation of PPG. There are stronger respiratory variations such as respiratory synchronous variation (PPGr) in ...
Authier S - - 2010
Female cynomolgus monkeys were surgically implanted with telemetry transmitters recording ECG (DII), arterial pressure, physical activity, body temperature, and tidal volume. Respiratory rate (RR) and tidal volume (TV) were monitored simultaneously with the telemetry transmitter using impedance. Impedance-based monitoring of RR and TV by telemetry correlated with controlled TV and ...
Roberge Raymond J - - 2010
This study evaluated the effect of exhaled moisture on the breathing resistance of three classes of filtering facepiece respirators (FFR) following 4 h of continuous wear at a breathing volume of 40 l min(-1), utilizing an automated breathing and metabolic simulator as a human surrogate. After 4 h, inhalation and ...
Nkosi N G - - 2010
Hypertension is a global, non-communicable chronic disease being asymptomatic and known as the silent killer with signs and symptoms only occurring when a target organ is damaged. Being a condition common in South Africa, hypertension is also a risk factor for cerebro-vascular incidents, myocardial infarction, left ventricular hypertrophy, renal disease ...
Modesti Pietro Amedeo - - 2010
BACKGROUND: The possibility that daily sessions of music-guided slow breathing may reduce 24-h ambulatory blood pressure (ABP), and predictors of efficacy were explored in a randomized, placebo-controlled trial with parallel design. METHODS: Age-matched and sex-matched hypertensive patients were randomized to music-guided slow breathing exercises (4-6 breaths/min; 1: 2 ratio of ...
Binggeli Christian - - 2010
OBJECTIVES: Intermittent periods of hypoxemia such as during periodic breathing are associated with hypertension and increased sympathetic activity. In patients with sleep apnea syndrome, hypertension is common. Treating apnea improves hypertension and reduces sympathetic outflow. The aim of the present study was to investigate the phenomenon and mechanisms of spontaneous ...
Sin Peter Y W - - 2010
The respiratory component of heart rate variability (respiratory sinus arrhythmia, RSA) has been associated with improved pulmonary gas exchange efficiency in humans via the apparent clustering and scattering of heart beats in time with the inspiratory and expiratory phases of alveolar ventilation, respectively. However, since human RSA causes only marginal ...
Scott D H T - - 2010
Invasive ventilation poses a risk of respiratory infection that can be drug-resistant. One means of reducing transmission of infection is the use of a breathing system filter. Filters are intended to be used with dry gas. Current international standards do not require that filters prevent bacterial transfer when wet. It ...
Delerme Samuel - - 2010
INTRODUCTION: Previous studies suggested that variation of pulse oximetric plethysmographic (POP) waveform amplitude (Delta POP) could predict fluid responsiveness in mechanically ventilated patients. Our objective was to correlate the variations of Delta POP and the variations of cardiac index (CI) induced by passive leg raising (PLR) in spontaneously breathing volunteers. ...
Henzler Dietrich - - 2010
PURPOSE: Ventilation problems are common in critically ill patients with intra-abdominal hypertension. The aim of this study was to investigate the effects of preserved spontaneous breathing during mechanical ventilation on hemodynamics, gas exchange, respiratory function and lung injury in experimental intra-abdominal hypertension. METHODS: Twenty anesthetized pigs were intubated and ventilated ...
Sin P Y W - - 2010
Respiratory sinus arrhythmia (RSA) is classically described as a vagally mediated increase and decrease in heart rate concurrent with inspiration and expiration, respectively. However, although breathing frequency is known to alter this temporal relationship, the precise nature of this phase dependency and its relationship to blood pressure remains unclear. In ...
Gavish Benjamin - - 2010
Routine practice of slow breathing is a major component of a variety of behavioral treatments of chronic conditions. The present paper addresses the challenge of using device-guided breathing (DGB) as a self-treatment tool in the home setting. The breathing patterns of hypertensive patients treated using DGB over 8 weeks in ...
Wu Chin-Pyng - - 2010
BACKGROUND: Adaptive support ventilation (ASV) is a new mode of mechanical ventilation that seeks an optimal breathing pattern based on the minimum work of breathing (WOB) principle. The operator's manual for the ventilators that provide ASV recommends that the %MinVol setting be started at 100% (the 100%MinVol setting), but it ...
Kondili Eumorfia - - 2010
Recently, a new technology has been introduced aiming to monitor and improve patient ventilator interaction (PVI monitor). With the PVI monitor, a signal representing an estimation of the patient's total inspiratory muscle pressure (Pmus(PVI)) is calculated from the equation of motion, utilizing estimated values of resistance and elastance of the ...
Kawabata Masashi - - 2010
Intra-abdominal pressure (IAP) is closely related to breathing behavior during lifting. Abdominal muscles contribute to both IAP development and respiratory function. The purpose of this study was to examine whether spontaneous breath volume and IAP altered with increased isometric lifting effort, and to compare the effect of different abdominal muscle ...
Markstr?m Agneta - - 2010
BACKGROUND: Bi-level Positive Airway Pressure (Bi-PAP) treatment improves breathing efficiency and ventilation in children with SMA type II, but the effects of positive airway pressure swings on heart rate (HR) and blood pressure are not known. Here we studied children with SMA to determine whether Bi-PAP administered during sleep is ...
Wong Frankie W H - - 2010
BACKGROUND: The hemodynamic information obtained from the pulmonary artery catheter provides physiologic rationale for a selected therapy and allows rapid determination of patients' response to the therapy. A wide range of pressure support levels have been used in pressure support ventilation (PSV), and patients' breathing patterns change from a spontaneous ...
Jones Chulee U - - 2010
Question: Can adding an inspiratory load enhance the antihypertensive effects of slow breathing training performed at home? Design: Randomised trial with concealed allocation. Participants: Thirty patients with essential hypertension stage I or II. Intervention: Experimental groups performed slow deep breathing at home, either unloaded or breathing against a load of ...
Cader Samária Ali - - 2010
Does inspiratory muscle training improve maximal inspiratory pressure in intubated older people? Does it improve breathing pattern and time to wean from mechanical ventilation? Randomised trial with concealed allocation and intention-to-treat analysis. 41 elderly, intubated adults who had been mechanically ventilated for at least 48 hr in an intensive care ...
Jones Chulee U - - 2010
Can adding an inspiratory load enhance the antihypertensive effects of slow breathing training performed at home? Randomised trial with concealed allocation. Thirty patients with essential hypertension Stage I or II. Experimental groups performed slow deep breathing at home, either unloaded or breathing against a load of 20 cmH(2)O using a ...
West John B - - 2010
The primary objective of the American Medical Research Expedition to Everest was to obtain information on human physiology at the highest possible altitude, including the Everest summit. An important data point was the barometric pressure on the summit, because this determines the inspired P(O(2)). The first measurement ever taken was ...
Aleksandrova N P - - 2010
Acute experiments on rats were performed to study the effects of intraventricular microinjections of gamma-aminobutyric acid (GABA) on the volume-time parameters of external respiration and the inspiration-inhibiting Hering-Breuer reflex. The state of this reflex before and after GABA administration was assessed in terms of the extent of changes in the ...
Taneja Indu I Department of Pediatrics, New York Medical College, Valhalla, NY, USA. - - 2010
We used breath-holding during inspiration as a model to study the effect of pulmonary stretch on sympathetic nerve activity. Twelve healthy subjects (7 females, 5 males; 19-27 years) were tested while they performed an inspiratory breath-hold, both supine and during a 60 degrees head-up tilt (HUT 60). Heart rate (HR), ...
Rubini A A Department of Human Anatomy and Physiology, Physiology Section, University of Padova, Padova, - - 2010
The effects of acute blood volume expansion (BVE) on the respiratory mechanics of normal animals have been not extensively studied. The subject is of both theoretical and practical interest since BVE is a frequent medical intervention, and the associated increase in cardiac output may occur in different physiopathological situations. To ...
Quinet P - - 2010
Twenty-five COPD patients, aged 65years or above, were recruited to test their ability to use dry powder inhaler Handihaler (Boeringher-Ingelheim) and Aerolizer (Novartis). The results of a score created to evaluate the inhalation technique were compared with age, MMSE, Barthel Index, FEV(1), maximum inspiratory and expiratory pressures, and peak inspiratory ...
Frisbie J H - - 2010
Case report. To describe a role for breathing in maintenance for blood pressure in a tetraplegic man. Veterans Administration Hospital, USA. A 60-year-old man, tetraplegic for 14 years, was successfully treated for orthostatic hypotension (OH) by raising the head of his bed in the mornings before transfer to his wheelchair. ...
Campoccia Jalde Francesca - - 2010
Neurally adjusted ventilatory assist (NAVA) is a pneumatically-independent mode of mechanical ventilation controlled by diaphragm electrical activity (EAdi), and has not yet been implemented in very small species. The aims of the study were to evaluate the feasibility of applying NAVA in very small species and to compare this to ...
Patel Kapil N - - 2009
BACKGROUND: The rapid-shallow-breathing index (RSBI) is widely used to evaluate mechanically ventilated patients for weaning and extubation, but it is determined in different clinical centers in a variety of ways, under conditions that are not always comparable. We hypothesized that the value of RSBI may be significantly influenced by common ...
Cruz José Roquennedy Souza JR Universidade Federal de Sergipe. - - 2009
The objective of the present study was to evaluate the degree of sedation, intraocular pressure, and hemodynamic changes with premedication with low doses of oral clonidine, 100 microg and 200 microg, in outpatient cataract surgeries. This is a randomized, double-blind, clinical study undertaken at the Universidade Federal de São Paulo ...
Terzi Nicolas - - 2010
Inspiratory muscle strength measurements have become a cornerstone in monitoring neuromuscular disorders. Usually, sniff nasal inspiratory pressure (SNIP) and maximal inspiratory pressure (MIP) are performed. To our knowledge the session-to-session learning effect has rarely been evaluated for MIP performance and has never been done for SNIP performance. We hypothesized that ...
Pinto Susana - - 2009
OBJECTIVE: Phrenic nerve motor amplitude (Diaphr Ampl) is predictive of hypoventilation in amyotrophic lateral sclerosis (ALS). We aimed to evaluate its change over disease course and to correlate it to other measurements. METHODS: Forty-nine unselected patients (35 men, 13 bulbar-onset, 56.5+/-8.9 years) with definitive or probable ALS were included. They ...
Smutney Chad C - - 2009
The Technosphere Insulin (TI) inhalation system comprises TI powder premetered into unit dose cartridges and the patient-friendly, reusable, breath-powered MedTone inhaler. This high-resistance system uses a patient's inspiratory effort to effect TI powder de-agglomeration and promote subsequent deep-lung delivery. This study reports on flow and pressure data achieved by patients ...
Andersson Johan P A - - 2009
Many competitive breath-hold divers use 'glossopharyngeal insufflation', also called 'lung packing', to overfill their lungs above normal total lung capacity. This increases intrathoracic pressure, decreases venous return, compromises cardiac pumping, and reduces arterial blood pressure, possibly resulting in a syncope breath-hold divers call 'packing blackout'. We report a case with ...
Le Parc R - - 2009
The structure of glasses in the binary system SiO(2)-GeO(2) has been studied by Raman spectroscopy. Our results are consistent with mixing of SiO(2) and GeO(2) tetrahedra. The changes induced by temperature and by pressure on the structure are monitored by in situ measurements on the same mixed glasses. Anomalous temperature ...
Guaraldi Pietro - - 2009
During maximal breath-holding six healthy elite breath-hold divers, after an initial "easy-going" phase in which cardiovascular changes resembled the so-called "diving response", exhibited a sudden and severe rise in blood pressure during the "struggle" phase of the maneuver. These changes may represent the first tangible expression of a defense reaction, ...
Finsy Vincent - - 2009
Vapour-phase adsorption and separation of the C8 alkyl aromatic compounds p-xylene, m-xylene, o-xylene, and ethylbenzene has been studied on the metal-organic framework MIL-53. Adsorption and desorption isotherms of the pure components at 110 degrees C were determined using the gravimetric technique. The adsorption isotherms show two well-defined steps and hysteresis, ...
Uchiyama Akinori - - 2009
BACKGROUND: Although inspiratory assist of spontaneous breathing in intubated patients is common, expiratory assist functions have rarely been reported. Effective expiratory support (ES) could be used to compensate for endotracheal tube (ETT) resistance during spontaneous breathing. In this study, we examined the performance of a new system designed to provide ...
Sheikh Ednan - - 2009
Newer generation anesthesia machines are equipped with a pressure support mode of ventilation, which can be used to support spontaneous ventilation in anesthetized patients. The Drager Apollo anesthesia machine uses an inspiratory limb hot-wire flow sensor to measure inspiratory flow rates. Detected flow rates that exceed the pressure support flow ...
Dick Thomas E TE Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Case Western Reserve University, Biomedical Research Bldg., BRB 319, 10900 Euclid Avenue, Cleveland, OH 44106-4941, USA. - - 2009
Cardio-respiratory coupling is reciprocal; it is expressed as respiratory-modulated sympathetic nerve activity and pulse-modulated respiratory motor activity. In the brainstem, the neuraxis controlling cardio-respiratory functions forms a ventrolateral cell column which extends to the dorsolateral (dl) pons. Our general working hypothesis is that these control systems converge at points with ...
Andersson Johan P A - - 2009
The concentration of the protein S100B in serum is used as a brain damage marker in various conditions. We wanted to investigate whether a voluntary, prolonged apnea in trained breath-hold divers resulted in an increase of S100B in serum. Nine trained breath-hold divers performed a protocol mimicking the procedures they ...
Pierson David J - - 2009
The cardiopulmonary physiology of dinosaurs-and especially of the long-necked sauropods, which grew much larger than any land animals before or since-should be inherently fascinating to anyone involved in respiratory care. What would the blood pressure be in an animal 12 m (40 ft) tall? How could airway resistance and dead ...
Chlif Mehdi - - 2009
The purpose of this study was to assess whether obesity induces changes in breathing pattern and ventilatory neural drive and mechanics. Measurements performed in 34 male obese subjects (BMI, 39+/-6 kg/m(2)) and 18 controls (BMI, 23+/-3 kg/m(2)) included anthropometric parameters, spirometry, breathing patterns, mouth occlusion pressure, maximal inspiratory pressure and ...
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