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Harcourt Edward R ER 1Neonatology, Royal Children's Hospital, Parkville, VIC, Australia. 2Clinical Technology Service, Royal Children's Hospital, Parkville, VIC, Australia. 3Neonatal Research, Royal Women's Hospital, Parkville, VIC, Australia. 4Neonatal Research, Murdoch Children's Research Institute, Parkville, VIC, Australia. 5Department of Paediatrics, Royal Hobart Hospital, Hobart, TAS, Australia. 6Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, Milano, Italy. 7Departments Paediatrics and Obstetrics and Gynaecology, University of Melbourne, Melbourne, VIC, - - 2014
The differences in performance of early generation high-frequency oscillators have been attributed to their distinct pressure and flow waveforms. Recently, five new oscillators have been commercially released. The objective of this study was to characterize the pressure and flow waveforms of eight commercially available oscillators. In vitro benchtop study. Tertiary ...
Gouinaud Laure L a Medical Gases Group, Air Liquide Santé International, Centre de Recherche Claude Delorme , 1 Chemin de la Porte des Loges, B.P. 126, Les Loges-en-Josas 78354 , - - 2014
A numerical pressure loss model previously used for adult human airways has been modified to simulate the inhalation pressure distribution in a healthy 9-month-old infant lung morphology model. Pressure distributions are calculated for air as well as helium and xenon mixtures with oxygen to investigate the effects of gas density ...
Abboud François - - 2014
Nearly two decades ago, we evaluated ten patients with obstructive sleep apnea (OSA). We determined that alarming nocturnal oscillations in arterial pressure and sympathetic nerve activity (SNA) were caused by regulatory coupling and neural interactions among SNA, apnea, and ventilation. Patients with OSA exhibited high levels of SNA when awake, ...
Szyld Edgardo E Research Department, FUNDASAMIN, Fundación para la Salud Materno Infantil, Buenos Aires, Argentina. Electronic address: - - 2014
To evaluate the effectiveness and safety of a T-piece resuscitator compared with a self-inflating bag for providing mask ventilation to newborns at birth. Newborns at ≥26 weeks gestational age receiving positive-pressure ventilation at birth were included in this multicenter cluster-randomized 2-period crossover trial. Positive-pressure ventilation was provided with either a self-inflating ...
Mansukhani Meghna P MP Sleep Medicine, Affiliated Communities Medical Center, 101 Willmar Avenue SW, Willmar, MN, - - 2014
For most patients with obstructive sleep apnea syndrome (OSA), continuous positive airway pressure (CPAP) is an effective therapy. However, for a subset of individuals, CPAP is either not effective or is poorly tolerated. Bilevel positive airway pressure (BPAP) is potentially capable of treating OSA at a lower mean pressure than ...
Nguyen Binh B Pulmonary/Critical Care Medicine, Fletcher Allen Health Care, Burlington, - - 2014
The current ventilatory care goal for acute respiratory distress syndrome (ARDS) and the only evidence-based approach for managing ARDS is to ventilate with a tidal volume (VT) of 6 mL/kg predicted body weight (PBW). However, it is not uncommon for some caregivers to feel inclined to deviate from this strategy ...
Vasanth Karthik R R Department of Anaesthesiology, Critical Care and Pain, Tata Memorial Hospital, Parel, Mumbai, 400012, - - 2014
The incidence of postoperative pharyngolaryngeal complications after laryngeal mask airway (LMA) insertion can be as high as 50 %. Over-inflation of the LMA cuff may be a causal factor. We conducted a single-centre parallel group randomised trial to determine whether maintaining LMA-ProSeal intra-cuff pressures below 60 cm H2O decreases postoperative pharyngolaryngeal complications. ...
Kus Alparslan A From the Medical Faculty of Kocaeli University, Department of Anesthesiology and Reanimation, Umuttepe/Kocaeli, - - 2014
Supraglottic airway devices such as the LMA-Supreme (LMA-S) and I-gel, which have an additional lumen for the insertion of a gastric tube, can be useful in the management of the difficult airway. To test the performance of these two devices in the difficult paediatric airway, we compared the size 2 ...
Linz Dominik D Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg/Saar, - - 2014
Obstructive sleep apnea (OSA) is associated with hypertension and the progression of chronic kidney disease (CKD). Renal sympathetic innervation contributes to either condition. We investigated the effect of renal sympathetic denervation (RDN) on blood pressure (BP), renal perfusion, and neurohumoral responses during and after repetitive obstructive apneas in a pig ...
Lopez-Navas Kristel - - 2014
Abstract The proper setting of support ventilation aims to follow the patients' demands, ensuring adequate assistance to their respiratory effort. Effort assessment is thus necessary. But invasive procedures like measuring transdiaphragmatic pressure (Pdi) are impractical in long-term ventilation. Our purpose was therefore the development of the Occlusion+Delta (O+D) method for ...
Thomas Peter P Department of Physiotherapy, Royal Brisbane and Women's Hospital, Brisbane, Australia. Electronic address: - - 2014
To compare the effect of semi-recumbent and sitting positions on gas exchange, respiratory mechanics and hemodynamics in patients weaning from mechanical ventilation. Upright positions are encouraged during rehabilitation of the critically ill but there effects have not been well described. A prospective, randomized, cross-over trial was conducted. Subjects were passively ...
Erdemir Aydin A Tepecik Education and Research Hospital, Department of Pediatrics, Neonatology Clinic, Yenisehir, Izmir, - - 2014
To compare the effects and short-term outcomes of pressure support ventilation with volume guarantee versus synchronized intermittent mandatory ventilation in the weaning phase of very low-birth weight infants with respiratory distress syndrome. Randomized controlled prospective study. Tertiary care neonatal unit. A total of 60 premature infants who were less than ...
Macrae Phoebe P a Department of Physical Medicine and Rehabilitation, School of Medicine , Johns Hopkins University , Baltimore , - - 2014
ABSTRACT Volitional control of autonomic responses, such as heart rate and blood pressure, can be facilitated with the use of augmented feedback. Oropharyngeal swallowing typically includes both volitional and reflexive components, offering a unique opportunity for observing how performance is affected by feedback. Sixteen healthy participants (M age = 29 years, ...
Pickerd Nicole N Department of Child Health, Cardiff University, Cardiff, United - - 2014
To compare tidal breathing on different continuous positive airway pressure (CPAP) devices and pressures and to serially measure tidal breathing during weaning off CPAP using electromagnetic inductive plethysmography. Using electromagnetic inductive plethysmography, tidal breathing was measured in 29 preterm infants receiving CPAP, gestational age 28 ± 2 weeks. Variable-flow nasal CPAP (nCPAP), bubble ...
Adelborg K K Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Research Center for Emergency Medicine, Aarhus University Hospital, Aarhus, - - 2014
Forty surf lifeguards attempted to ventilate a manikin through one out of three supraglottic airways inserted in random order: the Portex(®) Soft Seal(®) ; the Intersurgical(®) i-gel™; and the Ambu(®) AuraOnce™. We recorded the time to ventilate and the proportion of inflations that were successful, without and then with concurrent ...
White David E - - 2014
Continuous positive air pressure (CPAP) users frequently report troublesome symptoms of airway dryness and nasal congestion. Clinical investigations have demonstrated that supplementary humidification reduces these symptoms but the reason for their occurrence remains unexplained. Investigations using human computational air-conditioning models are unable to reproduce or quantify the apparent airway drying ...
Visaya Jiovani M JM Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College, New York, New - - 2014
IMPORTANCE Endoscopic balloon dilation is commonly performed in children with airway stenosis, but guidelines are needed for selecting safe and effective balloon inflation parameters. OBJECTIVE To determine the feasibility and safety of airway balloon dilation in live rabbits using a range of balloon diameters and pressures. DESIGN AND SETTING Prospective ...
Hoff Fabrícia C FC Intensive Care Unit, Hospital Mãe de Deus, Porto Alegre, Brazil; Graduate Program in Medical Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, - - 2014
Expiratory asynchrony during pressure support ventilation (PSV) has been recognized as a cause of patient discomfort, increased workload, and impaired weaning process. We evaluated breathing pattern, patient comfort, and patient effort during PSV comparing 2 flow termination criteria: fixed at 5% of peak inspiratory flow vs automatic, real-time, breath-by-breath adjustment ...
Pouraghaei Mahboob M Anesthesiology Research Team, Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, - - 2014
Laryngoscopy and tracheal intubation lead to the alteration of hemodynamic parameters, including blood pressure and heart rate, in traumatic patients who sustain rapid sequence intubation (RSI). Various drugs such as fentanyl, alfentanil and sufentanil have been used to modify these hemodynamic responses. The aim of the present study is to ...
Tracy Mark B MB Neonatal Intensive Care Unit, Westmead Hospital, Westmead, Sydney, Australia; Sydney Medical School, University of Sydney, Sydney, - - 2014
To determine changes in respiratory mechanics when chest compressions are added to mask ventilation, as recommended by the International Liaison Committee On Resuscitation (ILCOR) guidelines for newborn infants. Using a Laerdal Advanced Life Support leak-free baby manikin and a 240 mL self-inflating bag, 58 neonatal staff members were randomly paired ...
Owens Robert Llewellyn RL 1Brigham & Women's Hospital and Harvard Medical - - 2014
The upper airway is often modeled as a classical Starling resistor, featuring a constant inspiratory airflow, or plateau, over a range of downstream pressures. However, airflow tracings from clinical sleep studies often show an initial peak before the plateau. To conform to the Starling model, the initial peak must be ...
Wasserthal Lutz T LT University of Erlangen-Nuremberg, - - 2014
Respiration in insects is thought to be independent of the circulatory system because insects typically lack respiratory pigments and because oxygen transport occurs in the gaseous phase via a ramified tracheal system by diffusion and convection directly to the tissues. In the blowfly, as in other insects with periodic heartbeat ...
Ntoumenopoulos George G School of Physiotherapy, Australian Catholic University , North Sydney, New South Wales , Australia - - 2014
Abstract Background: Chest physiotherapy may aid sputum clearance during conventional ventilation. However, the role of chest physiotherapy during high-frequency oscillatory ventilation (HFOV) is unclear. This study aimed to determine the effects manually-assisted cough (MAC), postural drainage, saline instillation and airway suction during HFOV. Methods: This was an observational study of ...
Liu Rui R State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
This study evaluated the effect of high selective bilateral vagotomy of hilus pulmonis with video-assisted thoracoscopy on asthma. Eight dogs with skin sensitive to Ascaris suum antigens were randomly divided into groups A and B. Asthma was induced by aerosol inhalation of A suum antigens. Respiratory rate and peak airway ...
Yehya Nadir N 1Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. 2Division of Pediatric Critical Care Medicine, Department of Pediatrics and Public Health Science, Penn State Hershey Children's Hospital, Hershey, PA. 3Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, - - 2014
Children with an immunocompromised condition and requiring invasive mechanical ventilation have high risk of death. Such patients are commonly transitioned to rescue modes of nonconventional ventilation, including airway pressure release ventilation and high-frequency oscillatory ventilation, for acute respiratory distress syndrome refractory to conventional ventilation. Our aim was to describe our ...
Vaschetto Rosanna - - 2014
Interface choice is crucial for non-invasive ventilation (NIV) success. We compared a new interface, the helmet next (HN), with the facial mask (FM) and the standard helmet (HS) in twelve healthy volunteers. In this study, five NIV trials were randomly applied, preceded and followed by a trial of unassisted spontaneous ...
Bernad Elena S - - 2014
In this study, effects of serial stenosis on coronary hemodynamics were investigated in the human right coronary artery (RCA) using blood flow analysis. A 3-D model of a serial stenosed RCA was reconstructed based on multislice computerized tomography images. Numerical analysis examined the effect of multiple serial stenoses on the ...
Türköz Ayda A Department of Anesthesiology, Baskent University Istanbul Teaching and Medical Research Center, ─░stanbul, - - 2014
Aims and Objectives: We used near-infrared spectroscopy to document changes in cerebral tissue oxygen saturation (SctO 2 ) in response to ventilation mode alterations after bidirectional Glenn (BDG; superior cavopulmonary connection) procedure. We also determined whether spontaneous ventilation have a beneficial effect on hemodynamic status, lactate and SctO 2 when ...
Bergmann Ingo I Department of Anaesthesiology, Emergency and Intensive Care Medicine, University of Göttingen Medical School, Robert-Koch Str, 40, 37075 Göttingen, Germany. - - 2014
The conventional sequence when using supraglottic airway devices is insertion, cuff inflation and fixation. Our hypothesis was that a tighter fit of the cuff and tip could be achieved with a consequently lower incidence of air leak, better separation of gastrointestinal and respiratory tracts and less airway morbidity if the ...
Reddy Roopika R The Veterans Affairs Western New York Healthcare System, Western New York, Buffalo, New York; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New - - 2014
To systematically review the various modalities of positive airway pressure (PAP) in the treatment of opioid-related central sleep apnea (CSA). Systematic review. MEDLINE, the Cochrane Library, and EMBASE were screened through March 2013 to identify articles which investigated treatment of opioidrelated CSA with PAP. Eligible articles were identified in a ...
Jaillette Emmanuelle - - 2014
Despite the increasing use of non-invasive ventilation and high-flow nasal-oxygen therapy, intubation is still performed in a large proportion of critically ill patients. The aim of this narrative review is to discuss recent data on long-term intubation-related complications, such as microaspiration, and tracheal ischemic lesions. These complications are common in ...
Ayatollahi Vida - - 2014
Manipulation of the larynx, such as laryngoscopy and tracheal intubation, is associated with haemodynamic and cardiovascular responses. In microlaryngoscopic procedures, these responses are more severe than laryngoscopy for endotracheal intubation because in microlaryngoscopic surgeries laryngoscope fixes for a longer time (15-20 minutes compared to 15-30 seconds in tracheal intubation). This ...
Seresht L Mousavi LM Department of Obstetrics and Gynecology, Isfahan University of Medical Sciences, Isfahan, - - 2014
Appropriate determination of tidal volume (VT) is important for preventing ventilation induced lung injury. We compared hemodynamic and respiratory parameters in two conditions of receiving VTs calculated by using body weight (BW), which was estimated by measured height (HBW) or demi-span based body weight (DBW). This controlled-trial was conducted in ...
Morris Theresa T Centre of Human & Aerospace Physiological Sciences, King's College London, London, United - - 2014
Direct chest-wall percussion can reduce breathlessness in Chronic Obstructive Pulmonary Disease and respiratory function may be improved, in health and disease, by respiratory muscle training (RMT). We tested whether high-frequency airway oscillation (HFAO), a novel form of airflow oscillation generation can modulate induced dyspnoea and respiratory strength and/or patterns following ...
Chen Fong-Lin FL Institute of Medicine, Chung Shang Medical University, Taichung, Taiwan Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, - - 2014
This study presents a computational fluid dynamics (CFD) model to simulate the three-dimensional airflow in the trachea before and after the vascular ring surgery (VRS). The simulation was based on CT-scan images of the patients with the vascular ring diseases. The surface geometry of the tracheal airway was reconstructed using ...
Null Donald M DM Division of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, - - 2013
Background:Short-term high-frequency nasal ventilation (HFNV) of preterm neonates provides acceptable gas exchange compared to endotracheal intubation and intermittent mandatory ventilation (IMV). Whether long-term HFNV will provide acceptable gas exchange is unknown. We hypothesized that HFNV for up to 21d would lead to acceptable gas exchange at lower inspired oxygen (O2) ...
Fisher Daniel F DF Assistant Director, Respiratory Care Services, Massachusetts General Hospital, Boston, MA, - - 2013
Tracheal intubation is used to establish a secure airway in patients who require mechanical ventilation. Unexpected extubation can have serious complications including airway trauma and death. Various methods and devices have been developed to maintain endotracheal tube (ETT) security. Associated complications include pressure ulcers due to decreased tissue perfusion. Device ...
Oto Jun - - 2013
Upper airway obstruction (UAO) is a major problem in unconscious subjects making full face mask ventilation difficult. The mechanism of UAO in unconscious subjects shares many similarities with that of obstructive sleep apnea (OSA), especially the hypotonic upper airway seen during rapid eye movement sleep. Continuous positive airway pressure (CPAP) ...
Wignall Jamie R JR Department of Clinical Science and Services, The Royal Veterinary College, University of London, North Mymms, United - - 2013
To evaluate the effect of cuff presence and cuff inflation on airway pressure in an inspiratory model of canine tracheostomy. Ex vivo experimental study. Cadaver tracheas from Beagle dogs were attached aborally to a vacuum. Airway pressure and flow rate was measured before and after placement of tracheostomy tubes. None. ...
Kartali Nikoleta N Second Propaedeutic Clinic of Aristotelian University of Thessaloniki, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Greece, - - 2013
We aimed to evaluate the effect of continuous positive airway pressure (CPAP) therapy on blood pressure (BP) and arterial stiffness in hypertensive patients with obstructive sleep apnea (OSA). We studied 38 hypertensive patients who suffered from severe OSA. Ambulatory BP measurement was performed at baseline and after at least 3 months ...
Rognås Leif L aDepartment of Research and Development, Norwegian Air Ambulance Foundation, Drøbak, Norway bPre-Hospital Critical Care Team, Department of Anaesthesiology, Viborg Regional Hospital, Viborg cDepartment of Pre-hospital Medical Services, Central Denmark Region dPre-Hospital Critical Care Team eCentre for Emergency Medicine Research fDepartment of Anaesthesiology, Aarhus University Hospital, Aarhus N, - - 2013
Guidelines recommend that patients with brain trauma with a Glasgow Coma Scale (GCS) score of less than 9 should have an airway established. Hypoxia, hypotension and hypertension as well as hypoventilation and hyperventilation may worsen outcome in these patients. The objectives were to investigate guideline adherence, reasons for nonadherence and ...
Theerakittikul Theerakorn T Pulmonary Critical Care and Allergy Unit Department of Internal Medicine Faculty of Medicine Chiang Mai University Chiang Mai, - - 2013
Positive airway pressure in subjects with both obstructive sleep apnea and COPD reduces the risk of pulmonary hypertension, death and hospitalizations from COPD exacerbations, but adherence to the intervention is low, similar to the experience with noninvasive ventilation in stable COPD. We sought to assess whether hyperinflation on chest radiographs ...
Baleine Julien J Neonatal Intensive Care Unit, Department of Pediatrics, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, 34000 Montpellier, - - 2013
Neonates are often intubated in the delivery room (DR) without anesthesia because vascular access is impossible. To assess neonatal comfort and adverse events after use of nasal midazolam (nMDZ) for intubation in the DR. Prospective data collection over 6months on the intubation of neonates with respiratory distress requiring tracheal instillation ...
Oppersma Eline - - 2013
In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure rates for NIV remain high in specific patient categories. Several studies have identified factors that contribute to NIV failure, ...
Moore Colby - - 2013
In 1940, Scholander suggested that stiffened upper airways remained open and received air from highly compressible alveoli during marine mammal diving. There are little data available on the structural and functional adaptations of the marine mammal respiratory system. The aim of this research was to investigate the anatomical (gross) and ...
Suhitharan T T Department of Anaesthesia and Surgical Intensive Care, Changi General Hospital, 2 Simei Street 3, Singapore 529889. - - 2013
We describe a rare complication of acute unilateral submandibular gland swelling following the use of laryngeal mask airway (LMA) in two patients with otherwise uneventful perioperative airway management. This is likely to be a consequence of the pressure exerted by the airway cuff on the tissues within the submandibular triangle. ...
D'Souza Gavin - - 2013
Currently, diagnosis of coronary stenosis is primarily based on the well-established functional diagnostic parameter, fractional flow reserve. The threshold of FFR has a "gray" zone of 0.75-0.80, below which further clinical intervention is recommended. An alternate diagnostic parameter, pressure drop coefficient (CDP: ratio of trans-stenotic pressure drop to the proximal ...
Walmsley Megan M 1 Himalayan Rescue Association , Kathmandu, Nepal - - 2013
Abstract Walmsley, Megan. Continuous positive airway pressure as adjunct treatment of acute altitude illness. High Alt Med Biol 14:405-407, 2013.-Altitude related illness occurs in unacclimatized individuals ascending to altitudes over 2500 m. Treatment usually involves descending to lower altitudes and pharmacological therapies. There are very few cases, studies, or recommendations regarding ...
Engström Joakim - - 2013
Daily routine ventilator-filter exchange interrupts the integrity of the ventilator circuit. We hypothesized that this might reduce positive airway pressure in mechanically ventilated ICU patients, inducing alveolar collapse and causing impaired oxygenation and compliance of the respiratory system (CRS). 40 consecutive ICU patients (PaO2/FIO2 ratio ≤ 300 mm Hg), mechanically ...
Rizkalla Nicole A NA Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, - - 2013
High-frequency percussive ventilation (HFPV) in pediatrics has been described predominantly in burned patients. We aimed to describe its effectiveness and safety in noninhalational pediatric acute respiratory failure (ARF). We conducted an observational study in a tertiary care pediatric intensive care unit on 31 patients with ARF failing conventional ventilation transitioned ...
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