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Freedman Neil N Northshore University Health System 2151 Waukegan Road, Bannockburn, IL 60015 - - 2014
Obstructive sleep apnea (OSA) is common and is associated with a number of adverse outcomes, including an increased risk for cardiovascular disease. Typical treatment approaches, including positive airway pressure, oral appliances, various upper airway surgeries, and/or weight loss, can improve symptoms and reduce the severity of disease in select patient ...
Null Donald M DM Division of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, - - 2013
Background:Short-term high-frequency nasal ventilation (HFNV) of preterm neonates provides acceptable gas exchange compared to endotracheal intubation and intermittent mandatory ventilation (IMV). Whether long-term HFNV will provide acceptable gas exchange is unknown. We hypothesized that HFNV for up to 21d would lead to acceptable gas exchange at lower inspired oxygen (O2) ...
Fisher Daniel F DF Assistant Director, Respiratory Care Services, Massachusetts General Hospital, Boston, MA, - - 2013
Tracheal intubation is used to establish a secure airway in patients who require mechanical ventilation. Unexpected extubation can have serious complications including airway trauma and death. Various methods and devices have been developed to maintain endotracheal tube (ETT) security. Associated complications include pressure ulcers due to decreased tissue perfusion. Device ...
Wignall Jamie R JR Department of Clinical Science and Services, The Royal Veterinary College, University of London, North Mymms, United - - 2013
To evaluate the effect of cuff presence and cuff inflation on airway pressure in an inspiratory model of canine tracheostomy. Ex vivo experimental study. Cadaver tracheas from Beagle dogs were attached aborally to a vacuum. Airway pressure and flow rate was measured before and after placement of tracheostomy tubes. None. ...
Oto Jun - - 2013
Upper airway obstruction (UAO) is a major problem in unconscious subjects making full face mask ventilation difficult. The mechanism of UAO in unconscious subjects shares many similarities with that of obstructive sleep apnea (OSA), especially the hypotonic upper airway seen during rapid eye movement sleep. Continuous positive airway pressure (CPAP) ...
Kartali Nikoleta N Second Propaedeutic Clinic of Aristotelian University of Thessaloniki, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Greece, - - 2013
We aimed to evaluate the effect of continuous positive airway pressure (CPAP) therapy on blood pressure (BP) and arterial stiffness in hypertensive patients with obstructive sleep apnea (OSA). We studied 38 hypertensive patients who suffered from severe OSA. Ambulatory BP measurement was performed at baseline and after at least 3 months ...
Rognås Leif L aDepartment of Research and Development, Norwegian Air Ambulance Foundation, Drøbak, Norway bPre-Hospital Critical Care Team, Department of Anaesthesiology, Viborg Regional Hospital, Viborg cDepartment of Pre-hospital Medical Services, Central Denmark Region dPre-Hospital Critical Care Team eCentre for Emergency Medicine Research fDepartment of Anaesthesiology, Aarhus University Hospital, Aarhus N, - - 2013
Guidelines recommend that patients with brain trauma with a Glasgow Coma Scale (GCS) score of less than 9 should have an airway established. Hypoxia, hypotension and hypertension as well as hypoventilation and hyperventilation may worsen outcome in these patients. The objectives were to investigate guideline adherence, reasons for nonadherence and ...
Theerakittikul Theerakorn T Pulmonary Critical Care and Allergy Unit Department of Internal Medicine Faculty of Medicine Chiang Mai University Chiang Mai, - - 2013
Positive airway pressure in subjects with both obstructive sleep apnea and COPD reduces the risk of pulmonary hypertension, death and hospitalizations from COPD exacerbations, but adherence to the intervention is low, similar to the experience with noninvasive ventilation in stable COPD. We sought to assess whether hyperinflation on chest radiographs ...
Baleine Julien J Neonatal Intensive Care Unit, Department of Pediatrics, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, 34000 Montpellier, - - 2013
Neonates are often intubated in the delivery room (DR) without anesthesia because vascular access is impossible. To assess neonatal comfort and adverse events after use of nasal midazolam (nMDZ) for intubation in the DR. Prospective data collection over 6months on the intubation of neonates with respiratory distress requiring tracheal instillation ...
Oppersma Eline - - 2013
In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure rates for NIV remain high in specific patient categories. Several studies have identified factors that contribute to NIV failure, ...
Moore Colby - - 2013
In 1940, Scholander suggested that stiffened upper airways remained open and received air from highly compressible alveoli during marine mammal diving. There are little data available on the structural and functional adaptations of the marine mammal respiratory system. The aim of this research was to investigate the anatomical (gross) and ...
Suhitharan T T Department of Anaesthesia and Surgical Intensive Care, Changi General Hospital, 2 Simei Street 3, Singapore 529889. - - 2013
We describe a rare complication of acute unilateral submandibular gland swelling following the use of laryngeal mask airway (LMA) in two patients with otherwise uneventful perioperative airway management. This is likely to be a consequence of the pressure exerted by the airway cuff on the tissues within the submandibular triangle. ...
D'Souza Gavin - - 2013
Currently, diagnosis of coronary stenosis is primarily based on the well-established functional diagnostic parameter, fractional flow reserve. The threshold of FFR has a "gray" zone of 0.75-0.80, below which further clinical intervention is recommended. An alternate diagnostic parameter, pressure drop coefficient (CDP: ratio of trans-stenotic pressure drop to the proximal ...
Walmsley Megan M 1 Himalayan Rescue Association , Kathmandu, Nepal - - 2013
Abstract Walmsley, Megan. Continuous positive airway pressure as adjunct treatment of acute altitude illness. High Alt Med Biol 14:405-407, 2013.-Altitude related illness occurs in unacclimatized individuals ascending to altitudes over 2500 m. Treatment usually involves descending to lower altitudes and pharmacological therapies. There are very few cases, studies, or recommendations regarding ...
Engström Joakim - - 2013
Daily routine ventilator-filter exchange interrupts the integrity of the ventilator circuit. We hypothesized that this might reduce positive airway pressure in mechanically ventilated ICU patients, inducing alveolar collapse and causing impaired oxygenation and compliance of the respiratory system (CRS). 40 consecutive ICU patients (PaO2/FIO2 ratio ≤ 300 mm Hg), mechanically ...
Rizkalla Nicole A NA Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, - - 2013
High-frequency percussive ventilation (HFPV) in pediatrics has been described predominantly in burned patients. We aimed to describe its effectiveness and safety in noninhalational pediatric acute respiratory failure (ARF). We conducted an observational study in a tertiary care pediatric intensive care unit on 31 patients with ARF failing conventional ventilation transitioned ...
Wootton David M - - 2013
Rationale: Computational fluid dynamics (CFD) analysis may quantify the severity of anatomical airway restriction in obstructive sleep apnea syndrome (OSAS) better than anatomical measurements alone. However, optimal CFD model endpoints to characterize or assess OSAS have not been determined. Objectives: To model upper airway fluid dynamics using CFD and investigate ...
Carter Eleanor L - - 2013
Ventilation-associated pneumonia (VAP) is the commonest nosocomial infection in intensive care. Implementation of a VAP prevention care bundle is a proven method to reduce its incidence. The UK care bundle recommends maintenance of the tracheal tube cuff pressure at 20 to 30 cmH2O with 4-hourly pressure checks and use of tracheal ...
Kim Min-Soo MS Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 120-752, Republic of - - 2013
This single-center, prospective, randomized, double-blind, 2-arm, parallel group comparison trial was performed to establish whether the adult-sized laryngeal mask airway (LMA) Classic (The Laryngeal Mask Company Ltd, Henley-on-Thames, UK) could be used safely without any consideration of cuff hyperinflation when a cuff of the LMA Classic was inflated using half ...
Barjaktarevic Igor - - 2013
Endotracheal intubation is difficult in patients with hypoxemic respiratory failure who deteriorate despite treatment with noninvasive positive pressure ventilation (NIPPV). Maintaining NIPPV during intubation may prevent alveolar derecruitment and deterioration in gas exchange. We report a case series of 10 nonconsecutive patients with NIPPV failure who were intubated via a ...
Chantzara G - - 2013
Background: Pharyngolaryngeal discomfort is a significant complication following the use of laryngeal mask airway (LMA). The present study aimed to investigate the relation of LMA cuff pressure and the occurrence of pharyngolaryngeal discomfort during spontaneous ventilation (SV), pressure support (PSV) and pressure control ventilation (PCV). Methods: 120 patients, ASA I-III, ...
Sasano Nobuko - - 2013
Percutaneous transtracheal ventilation (PTV) can be life-saving in a cannot ventilate, cannot intubate situation. The aim of this study was to investigate the efficacy of PTV by measuring tidal volumes (VTs) and airway pressure (Paw) in high-flow oxygen ventilation and manual ventilation using a model lung. We examined 14G, 16G, ...
Birkenfeld Falk F Institute of Anatomy, Christian-Albrechts University, Kiel, - - 2013
The aim of the study was to evaluate the leakage of liquid past the cuffs of tracheal tubes in fresh frozen human heads. Six truncated fresh frozen heads were used and intubated with 8.0 mm endotracheal tubes. The intracuff pressures tested were 30 and 100 cmH2O. Subsequently, 20 ml of ...
Marjanovic Nicolas - - 2013
In the absence of endotracheal intubation, the manual bag-valve is the most frequently used ventilation technique during resuscitation. The efficiency of other devices has been poorly studied. The bench-test study described here was designed to evaluate the effectiveness of an automatic, manually-triggered system, and to compare it with manual bag ...
Efe Esra Mercanooglu EM Department of Anesthesiology and Reanimation, Ankara University Medical Faculty, Ankara, Turkey. Electronic address: - - 2014
The aim of this randomized, prospective and double blinded study is to investigate effects of different esmolol use on hemodynamic response of laryngoscopy, endotracheal intubation and sternotomy in coronary artery bypass graft surgery. After approval of local ethics committee and patients' written informed consent, 45 patients were randomized into three ...
Patel Shreya - - 2013
Uncuffed endotracheal tubes are still preferred over cuffed tubes in certain situations in pediatric anesthesia. Inaccurately sized uncuffed endotracheal tubes may lead to inadequate ventilation or tracheal mucosal damage during anesthesia. Endotracheal tube size in children is usually assessed by measuring the audible leak pressure; if the fit of the ...
Cedborg Anna I Hårdemark - - 2013
Intact pharyngeal function and coordination of breathing and swallowing are essential for airway protection and to avoid respiratory complications. Postoperative pulmonary complications caused by residual effects of neuromuscular-blocking agents occur more frequently in the elderly. Moreover, elderly have altered pharyngeal function which is associated with increased risk of aspiration. The ...
Kill Clemens - - 2013
Mechanical ventilation with an automated ventilator is recommended during cardiopulmonary resuscitation with a secured airway. We investigated the influence of intermittent positive-pressure ventilation, bilevel ventilation, and the novel ventilator mode chest compression synchronized ventilation, a pressure-controlled ventilation triggered by each chest compression, on gas exchange, hemodynamics, and return of spontaneous ...
Maitra Souvik - - 2013
Laryngeal mask airway (LMA) Supreme is a newly introduced single-use supraglottic device, which shares common features of both the LMA Pro-Seal and the intubating LMA (ILMA). Clinical studies have compared the safety and efficacy of the LMA Supreme over the 'gold standard' LMA Pro-Seal in different patient populations. However, the ...
Wilson Emily V - - 2013
Ventilation during neonatal resuscitation is typically initiated with a face mask, but may be ineffective due to leak or obstruction. To compare leak using three methods of mask hold. Medical and nursing staff regularly involved in neonatal resuscitation used the three holds (two-point, two-handed, spider) on a manikin in a ...
Sinderby Christer - - 2013
The aim of this study was to validate an automated, objective and standardized algorithm for quantifying and displaying patient-ventilator interaction. Using a new method to detect patient-ventilator synchrony, the present study re-analyzed previously acquired and published data from 24 mechanically ventilated adult patients (Colombo et al., Crit Care Med. 2011 ...
Wong David T - - 2013
Excessive supraglottic airway cuff pressure increases postoperative pharyngolaryngeal symptoms such as sore throat, dysphonia, and dysphagia. A new supraglottic airway, AES Ultra CPV™ (CPV), has a built-in intracuff pressure indicator. We hypothesized that using the CPV would reduce postoperative symptoms when compared with the LMA Classic™ (LMA) without intracuff pressure ...
Bach John Robert - - 2013
Mechanically assisted coughing is the combination of mechanical insufflation-exsufflation to the airways in conjunction with an exsufflation-timed abdominal thrust. It has permitted in-home long-term survival of respirator-dependent users of continuous noninvasive intermittent positive pressure ventilatory support in the United States since shortly after it became available in 1952. By contrast, ...
Talikoti Anand T - - 2013
Endotracheal intubation is sine quo non for safe conduct of general anaesthesia. Pregabalin, an anticonvulsant drug is being studied for control of haemodynamic response to laryngoscopy and intubation. Some authors have found that pregabalin 150 mg orally attenuates the haemodynamic response to laryngoscopy. The purpose of the present study was ...
Gilstrap Daniel - - 2013
Assisted/supported modes of mechanical ventilation offer significant advantages over controlled modes in terms of ventilator muscle function/recovery and patient comfort (and sedation needs). However, assisted/supported breaths must interact with patient demands during all three phases of breath delivery: trigger, target and cycle. Synchronous interactions match ventilator support with patient demands; ...
Fava Cristiano - - 2013
Continuous positive airway pressure (cPAP) is considered the therapy of choice for obstructive sleep apnea (OSA), but the extent to which it can reduce blood pressure (BP) is still under debate.We undertook a systematic review and meta-analysis of randomized controlled trials (RCTs) to quantify the effect size of the reduction ...
Qaseem Amir - - 2013
The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on the management of obstructive sleep apnea (OSA) in adults. This guideline is based on published literature from 1966 to September 2010 that was identified by using MEDLINE, the Cochrane Central Register of ...
Liesching Timothy - - 2013
Studies have shown different clinical outcomes of noninvasive positive pressure ventilation (NPPV) from those of continuous positive airway pressure (CPAP). We evaluated whether bilevel positive airway pressure (BPAP) more rapidly improves dyspnea, ventilation, and acidemia without increasing the myocardial infarction (MI) rate compared to continuous positive pressure ventilation (CPAP) in ...
Vasconcelos Renata Dos S - - 2013
Background: The digital Auto-Trak™ system is a technology capable of automatically adjusting the triggering and cycling mechanisms during pressure support ventilation (PSV). Objective: To compare Auto-Trak with conventional settings in terms of patient-ventilator synchrony and discomfort. Methods: Twelve healthy volunteers underwent PSV via the mouth by breathing through an endotracheal ...
Rittayamai Nuttapol - - 2013
To compare the short term benefit of high-flow nasal oxygen cannula (HFNC) with non-rebreathing mask in terms of change of dyspnea, physiologic variables, and patient comfort in subjects after endotracheal extubation. A randomized cross-over study was conducted in a 10-bed respiratory care unit in a university hospital. Seventeen mechanically ventilated ...
Wood Fiona E - - 2013
Face mask ventilation provides respiratory support to newly born or sick infants. It is a challenging technique and difficult to ensure that an appropriate tidal volume is delivered because large and variable leaks occur between the mask and face; airway obstruction may also occur. Technique is more important than the ...
van Vonderen Jeroen J - - 2013
Background: During mask ventilation, the mask volume can vary as it is pressurized or when it is squeezed. The change in volume of the mask may affect tidal volumes delivered and difference in inspired (Vti) and expired tidal volumes (Vte). Objectives: To investigate whether hand squeeze and distensibility of the ...
Kuo Alexander S - - 2013
To quantify inspiratory flow resistance of instrumented single-lumen and double-lumen endotracheal tubes. Bench-top in vitro experiments. Laboratory of a university hospital. In vitro lung simulator. A lung simulator was ventilated mechanically via several single- and double-lumen endotracheal tubes (ETT) that were instrumented with adult and pediatric bronchoscopes as well as ...
Derosa Savino - - 2013
Little is known about the small airways dysfunction in acute respiratory distress syndrome (ARDS). By computed tomography (CT) imaging in a porcine experimental model of early ARDS, we aimed at studying the location and magnitude of peripheral airway closure and alveolar collapse under high and low distending pressures and high ...
Ferdowsali Kameron - - 2013
Airway pressure release ventilation (APRV) is a mode of ventilation that has been around since the 1980s and was originally viewed as a type of continuous positive pressure mode of ventilation. Conceptually, APRV can be thought of as a type of inverse-ratio, pressure-controlled, intermittent mandatory ventilation during which the maintenance ...
Cerqueira Manoel Luiz de ML - - 2013
To evaluate the effects of physiotherapeutic respiratory maneuvers on cerebral and cardiovascular hemodynamics and blood gas variables. A descriptive, longitudinal, prospective, nonrandomized clinical trial that included 20 critical patients with severe craniocerebral trauma who were receiving mechanical ventilation and who were admitted to the intensive care unit. Each patient was ...
Wongsritrang Krongthong - - 2013
To compare the clinical outcomes and determine the difference in therapeutic pressure between Automatic positive airway pressure (APAP) and polysomnography manual titration. Fifty patients of obstructive sleep apnea (OSA), moderate to severe cases, were randomized into two groups of intervention: 95-percentile pressure derived from APAP titration and an optimal pressure ...
Johnson Pamela L PL 1 David Read Laboratory, University of Sydney , Sydney, NSW Australia - - 2013
Acute mountain sickness (AMS) is very common at altitudes above 2500 m. There are few treatment options in the field where electricity availability is limited, and medical assistance or oxygen is unavailable or difficult to access. Positive airway pressure has been used to treat AMS at 3800 m. We hypothesized ...
Pitts Teresa - - 2013
Airway protection is the prevention and/or removal of material by behaviors, such as cough and swallow. We tested the hypothesis that cough and swallow, in response to aspiration, are a "meta-behavior" and thus are coordinated and have alterations in excitability to respond to aspiration risk and maintain homeostasis. Anesthetized animals ...
Vagheggini Guido - - 2013
Neurally adjusted ventilatory assist (NAVA) is a mode of ventilation wherein the delivered assistance is proportional to diaphragm electrical activity (EAdi) throughout inspiration. We assessed the physiologic response to varying levels of NAVA and pressure support ventilation (PSV) in 13 tracheostomised patients with prolonged weaning. Each patient randomly underwent 8 ...
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