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Liu Rui R State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
This study evaluated the effect of high selective bilateral vagotomy of hilus pulmonis with video-assisted thoracoscopy on asthma. Eight dogs with skin sensitive to Ascaris suum antigens were randomly divided into groups A and B. Asthma was induced by aerosol inhalation of A suum antigens. Respiratory rate and peak airway ...
Yehya Nadir N 1Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA. 2Division of Pediatric Critical Care Medicine, Department of Pediatrics and Public Health Science, Penn State Hershey Children's Hospital, Hershey, PA. 3Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, - - 2014
Children with an immunocompromised condition and requiring invasive mechanical ventilation have high risk of death. Such patients are commonly transitioned to rescue modes of nonconventional ventilation, including airway pressure release ventilation and high-frequency oscillatory ventilation, for acute respiratory distress syndrome refractory to conventional ventilation. Our aim was to describe our ...
Vaschetto Rosanna - - 2014
Interface choice is crucial for non-invasive ventilation (NIV) success. We compared a new interface, the helmet next (HN), with the facial mask (FM) and the standard helmet (HS) in twelve healthy volunteers. In this study, five NIV trials were randomly applied, preceded and followed by a trial of unassisted spontaneous ...
Bernad Elena S - - 2014
In this study, effects of serial stenosis on coronary hemodynamics were investigated in the human right coronary artery (RCA) using blood flow analysis. A 3-D model of a serial stenosed RCA was reconstructed based on multislice computerized tomography images. Numerical analysis examined the effect of multiple serial stenoses on the ...
Türköz Ayda A Department of Anesthesiology, Baskent University Istanbul Teaching and Medical Research Center, İstanbul, - - 2014
Aims and Objectives: We used near-infrared spectroscopy to document changes in cerebral tissue oxygen saturation (SctO 2 ) in response to ventilation mode alterations after bidirectional Glenn (BDG; superior cavopulmonary connection) procedure. We also determined whether spontaneous ventilation have a beneficial effect on hemodynamic status, lactate and SctO 2 when ...
Bergmann Ingo I Department of Anaesthesiology, Emergency and Intensive Care Medicine, University of Göttingen Medical School, Robert-Koch Str, 40, 37075 Göttingen, Germany. - - 2014
The conventional sequence when using supraglottic airway devices is insertion, cuff inflation and fixation. Our hypothesis was that a tighter fit of the cuff and tip could be achieved with a consequently lower incidence of air leak, better separation of gastrointestinal and respiratory tracts and less airway morbidity if the ...
Reddy Roopika R The Veterans Affairs Western New York Healthcare System, Western New York, Buffalo, New York; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New - - 2014
To systematically review the various modalities of positive airway pressure (PAP) in the treatment of opioid-related central sleep apnea (CSA). Systematic review. MEDLINE, the Cochrane Library, and EMBASE were screened through March 2013 to identify articles which investigated treatment of opioidrelated CSA with PAP. Eligible articles were identified in a ...
Jaillette Emmanuelle - - 2014
Despite the increasing use of non-invasive ventilation and high-flow nasal-oxygen therapy, intubation is still performed in a large proportion of critically ill patients. The aim of this narrative review is to discuss recent data on long-term intubation-related complications, such as microaspiration, and tracheal ischemic lesions. These complications are common in ...
Ayatollahi Vida - - 2014
Manipulation of the larynx, such as laryngoscopy and tracheal intubation, is associated with haemodynamic and cardiovascular responses. In microlaryngoscopic procedures, these responses are more severe than laryngoscopy for endotracheal intubation because in microlaryngoscopic surgeries laryngoscope fixes for a longer time (15-20 minutes compared to 15-30 seconds in tracheal intubation). This ...
Seresht L Mousavi LM Department of Obstetrics and Gynecology, Isfahan University of Medical Sciences, Isfahan, - - 2014
Appropriate determination of tidal volume (VT) is important for preventing ventilation induced lung injury. We compared hemodynamic and respiratory parameters in two conditions of receiving VTs calculated by using body weight (BW), which was estimated by measured height (HBW) or demi-span based body weight (DBW). This controlled-trial was conducted in ...
Morris Theresa T Centre of Human & Aerospace Physiological Sciences, King's College London, London, United - - 2014
Direct chest-wall percussion can reduce breathlessness in Chronic Obstructive Pulmonary Disease and respiratory function may be improved, in health and disease, by respiratory muscle training (RMT). We tested whether high-frequency airway oscillation (HFAO), a novel form of airflow oscillation generation can modulate induced dyspnoea and respiratory strength and/or patterns following ...
Chen Fong-Lin FL Institute of Medicine, Chung Shang Medical University, Taichung, Taiwan Department of Pediatrics, Chung Shan Medical University Hospital, Taichung, - - 2014
This study presents a computational fluid dynamics (CFD) model to simulate the three-dimensional airflow in the trachea before and after the vascular ring surgery (VRS). The simulation was based on CT-scan images of the patients with the vascular ring diseases. The surface geometry of the tracheal airway was reconstructed using ...
Bakker Jessie P JP Division of Sleep Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston - - 2014
We sought to perform a patient-level meta-analysis using the individual patient data of the trials identified in our previous study-level meta-analysis investigating the effect of positive airway pressure (PAP) treatment for obstructive sleep apnea (OSA) on blood pressure (BP). Patient-level meta-analysis. N/A. 968 adult OSA subjects without major comorbidities drawn ...
Stewart Joshua C JC Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington School of Medicine, Seattle, Washington, - - 2014
Airway management is the most important clinical skill for anesthesiologist, emergency physician, and other providers who are involved in oxygenation and ventilation of the lungs. Rapid-sequence intubation is the preferred method to secure airway in patients who are at risk for aspiration because it results in rapid unconsciousness (induction) and ...
Carlson Jestin N - - 2014
ABSTRACTObjective:Pulmonary aspiration of gastric contents occurs 20 to 30% of the time during cardiopulmonary resuscitation (CPR) of cardiac arrest due to loss of protective airway reflexes, pressure changes generated during CPR, and positive pressure ventilation (PPV). Although the American Heart Association has recommended the laryngeal mask airway (LMA) as an ...
Kord Valeshabad Ali A Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, IL 60612, - - 2014
The purpose of this study is to assess the effects of propacetamol on attenuating hemodynamic responses subsequent laryngoscopy and tracheal intubation compared to lidocaine. In this randomized clinical trial, 62 patients with the American Anesthesiologists Society (ASA) class I/II who required laryngoscopy and tracheal intubation for elective surgery were assigned ...
Bussoni Marjory Fernanda MF Departamento de Clínica Médica, Faculdade de Medicina de Botucatu (UNESP), Botucatu, SP, - - 2014
The effects of acute continuous positive airway pressure therapy on left ventricular diastolic function and functional capacity in patients with compensated systolic heart failure remain unclear. This randomized, double-blind, placebo-controlled clinical trial included 43 patients with heart failure and a left ventricular ejection fraction <0.50 who were in functional classes ...
Freedman Neil N Northshore University Health System 2151 Waukegan Road, Bannockburn, IL 60015 - - 2014
Obstructive sleep apnea (OSA) is common and is associated with a number of adverse outcomes, including an increased risk for cardiovascular disease. Typical treatment approaches, including positive airway pressure, oral appliances, various upper airway surgeries, and/or weight loss, can improve symptoms and reduce the severity of disease in select patient ...
Olesen Niels D ND Department of Anesthesia, Rigshospitalet, University of Copenhagen Copenhagen, - - 2014
A siphon is suggested to support cerebral blood flow but appears not to be established because internal jugular venous (IJV) pressure is close to zero in upright humans. Thus, in eleven young healthy males, IJV pressure was 9 ± 1 mmHg (mean ± SE) when supine and fell to 3 ...
Abd-Elsayed Alaa A AA Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison, - - 2014
Stroke is a leading cause of death and disability worldwide. Aneurysmal subarachnoid hemorrhage (aSAH), a significant cause of hemorrhagic stroke, continues to have poor prognosis. Early diagnosis and treatment are key to improving outcomes. Subarachnoid hemorrhage (SAH) and aSAH are often accompanied by multiple comorbidities, making anesthetic management of these ...
Null Donald M DM Division of Neonatology, Department of Pediatrics, University of Utah, Salt Lake City, - - 2013
Background:Short-term high-frequency nasal ventilation (HFNV) of preterm neonates provides acceptable gas exchange compared to endotracheal intubation and intermittent mandatory ventilation (IMV). Whether long-term HFNV will provide acceptable gas exchange is unknown. We hypothesized that HFNV for up to 21d would lead to acceptable gas exchange at lower inspired oxygen (O2) ...
Fisher Daniel F DF Assistant Director, Respiratory Care Services, Massachusetts General Hospital, Boston, MA, - - 2013
Tracheal intubation is used to establish a secure airway in patients who require mechanical ventilation. Unexpected extubation can have serious complications including airway trauma and death. Various methods and devices have been developed to maintain endotracheal tube (ETT) security. Associated complications include pressure ulcers due to decreased tissue perfusion. Device ...
Wignall Jamie R JR Department of Clinical Science and Services, The Royal Veterinary College, University of London, North Mymms, United - - 2013
To evaluate the effect of cuff presence and cuff inflation on airway pressure in an inspiratory model of canine tracheostomy. Ex vivo experimental study. Cadaver tracheas from Beagle dogs were attached aborally to a vacuum. Airway pressure and flow rate was measured before and after placement of tracheostomy tubes. None. ...
Oto Jun - - 2013
Upper airway obstruction (UAO) is a major problem in unconscious subjects making full face mask ventilation difficult. The mechanism of UAO in unconscious subjects shares many similarities with that of obstructive sleep apnea (OSA), especially the hypotonic upper airway seen during rapid eye movement sleep. Continuous positive airway pressure (CPAP) ...
Kartali Nikoleta N Second Propaedeutic Clinic of Aristotelian University of Thessaloniki, Ippokrateio General Hospital of Thessaloniki, Thessaloniki, Greece, - - 2013
We aimed to evaluate the effect of continuous positive airway pressure (CPAP) therapy on blood pressure (BP) and arterial stiffness in hypertensive patients with obstructive sleep apnea (OSA). We studied 38 hypertensive patients who suffered from severe OSA. Ambulatory BP measurement was performed at baseline and after at least 3 months ...
Rognås Leif L aDepartment of Research and Development, Norwegian Air Ambulance Foundation, Drøbak, Norway bPre-Hospital Critical Care Team, Department of Anaesthesiology, Viborg Regional Hospital, Viborg cDepartment of Pre-hospital Medical Services, Central Denmark Region dPre-Hospital Critical Care Team eCentre for Emergency Medicine Research fDepartment of Anaesthesiology, Aarhus University Hospital, Aarhus N, - - 2013
Guidelines recommend that patients with brain trauma with a Glasgow Coma Scale (GCS) score of less than 9 should have an airway established. Hypoxia, hypotension and hypertension as well as hypoventilation and hyperventilation may worsen outcome in these patients. The objectives were to investigate guideline adherence, reasons for nonadherence and ...
Theerakittikul Theerakorn T Pulmonary Critical Care and Allergy Unit Department of Internal Medicine Faculty of Medicine Chiang Mai University Chiang Mai, - - 2013
Positive airway pressure in subjects with both obstructive sleep apnea and COPD reduces the risk of pulmonary hypertension, death and hospitalizations from COPD exacerbations, but adherence to the intervention is low, similar to the experience with noninvasive ventilation in stable COPD. We sought to assess whether hyperinflation on chest radiographs ...
Baleine Julien J Neonatal Intensive Care Unit, Department of Pediatrics, Arnaud de Villeneuve Hospital, Montpellier University Hospital Center, 34000 Montpellier, - - 2013
Neonates are often intubated in the delivery room (DR) without anesthesia because vascular access is impossible. To assess neonatal comfort and adverse events after use of nasal midazolam (nMDZ) for intubation in the DR. Prospective data collection over 6months on the intubation of neonates with respiratory distress requiring tracheal instillation ...
Oppersma Eline - - 2013
In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure rates for NIV remain high in specific patient categories. Several studies have identified factors that contribute to NIV failure, ...
Moore Colby - - 2013
In 1940, Scholander suggested that stiffened upper airways remained open and received air from highly compressible alveoli during marine mammal diving. There are little data available on the structural and functional adaptations of the marine mammal respiratory system. The aim of this research was to investigate the anatomical (gross) and ...
Suhitharan T T Department of Anaesthesia and Surgical Intensive Care, Changi General Hospital, 2 Simei Street 3, Singapore 529889. - - 2013
We describe a rare complication of acute unilateral submandibular gland swelling following the use of laryngeal mask airway (LMA) in two patients with otherwise uneventful perioperative airway management. This is likely to be a consequence of the pressure exerted by the airway cuff on the tissues within the submandibular triangle. ...
D'Souza Gavin - - 2013
Currently, diagnosis of coronary stenosis is primarily based on the well-established functional diagnostic parameter, fractional flow reserve. The threshold of FFR has a "gray" zone of 0.75-0.80, below which further clinical intervention is recommended. An alternate diagnostic parameter, pressure drop coefficient (CDP: ratio of trans-stenotic pressure drop to the proximal ...
Walmsley Megan M 1 Himalayan Rescue Association , Kathmandu, Nepal - - 2013
Abstract Walmsley, Megan. Continuous positive airway pressure as adjunct treatment of acute altitude illness. High Alt Med Biol 14:405-407, 2013.-Altitude related illness occurs in unacclimatized individuals ascending to altitudes over 2500 m. Treatment usually involves descending to lower altitudes and pharmacological therapies. There are very few cases, studies, or recommendations regarding ...
Engström Joakim - - 2013
Daily routine ventilator-filter exchange interrupts the integrity of the ventilator circuit. We hypothesized that this might reduce positive airway pressure in mechanically ventilated ICU patients, inducing alveolar collapse and causing impaired oxygenation and compliance of the respiratory system (CRS). 40 consecutive ICU patients (PaO2/FIO2 ratio ≤ 300 mm Hg), mechanically ...
Rizkalla Nicole A NA Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, - - 2013
High-frequency percussive ventilation (HFPV) in pediatrics has been described predominantly in burned patients. We aimed to describe its effectiveness and safety in noninhalational pediatric acute respiratory failure (ARF). We conducted an observational study in a tertiary care pediatric intensive care unit on 31 patients with ARF failing conventional ventilation transitioned ...
Wootton David M - - 2013
Rationale: Computational fluid dynamics (CFD) analysis may quantify the severity of anatomical airway restriction in obstructive sleep apnea syndrome (OSAS) better than anatomical measurements alone. However, optimal CFD model endpoints to characterize or assess OSAS have not been determined. Objectives: To model upper airway fluid dynamics using CFD and investigate ...
Carter Eleanor L - - 2013
Ventilation-associated pneumonia (VAP) is the commonest nosocomial infection in intensive care. Implementation of a VAP prevention care bundle is a proven method to reduce its incidence. The UK care bundle recommends maintenance of the tracheal tube cuff pressure at 20 to 30 cmH2O with 4-hourly pressure checks and use of tracheal ...
Kim Min-Soo MS Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 120-752, Republic of - - 2013
This single-center, prospective, randomized, double-blind, 2-arm, parallel group comparison trial was performed to establish whether the adult-sized laryngeal mask airway (LMA) Classic (The Laryngeal Mask Company Ltd, Henley-on-Thames, UK) could be used safely without any consideration of cuff hyperinflation when a cuff of the LMA Classic was inflated using half ...
Barjaktarevic Igor - - 2013
Endotracheal intubation is difficult in patients with hypoxemic respiratory failure who deteriorate despite treatment with noninvasive positive pressure ventilation (NIPPV). Maintaining NIPPV during intubation may prevent alveolar derecruitment and deterioration in gas exchange. We report a case series of 10 nonconsecutive patients with NIPPV failure who were intubated via a ...
Chantzara G - - 2013
Background: Pharyngolaryngeal discomfort is a significant complication following the use of laryngeal mask airway (LMA). The present study aimed to investigate the relation of LMA cuff pressure and the occurrence of pharyngolaryngeal discomfort during spontaneous ventilation (SV), pressure support (PSV) and pressure control ventilation (PCV). Methods: 120 patients, ASA I-III, ...
Sasano Nobuko - - 2013
Percutaneous transtracheal ventilation (PTV) can be life-saving in a cannot ventilate, cannot intubate situation. The aim of this study was to investigate the efficacy of PTV by measuring tidal volumes (VTs) and airway pressure (Paw) in high-flow oxygen ventilation and manual ventilation using a model lung. We examined 14G, 16G, ...
Birkenfeld Falk F Institute of Anatomy, Christian-Albrechts University, Kiel, - - 2013
The aim of the study was to evaluate the leakage of liquid past the cuffs of tracheal tubes in fresh frozen human heads. Six truncated fresh frozen heads were used and intubated with 8.0 mm endotracheal tubes. The intracuff pressures tested were 30 and 100 cmH2O. Subsequently, 20 ml of ...
Marjanovic Nicolas - - 2013
In the absence of endotracheal intubation, the manual bag-valve is the most frequently used ventilation technique during resuscitation. The efficiency of other devices has been poorly studied. The bench-test study described here was designed to evaluate the effectiveness of an automatic, manually-triggered system, and to compare it with manual bag ...
Efe Esra Mercanooglu EM Department of Anesthesiology and Reanimation, Ankara University Medical Faculty, Ankara, Turkey. Electronic address: - - 2014
The aim of this randomized, prospective and double blinded study is to investigate effects of different esmolol use on hemodynamic response of laryngoscopy, endotracheal intubation and sternotomy in coronary artery bypass graft surgery. After approval of local ethics committee and patients' written informed consent, 45 patients were randomized into three ...
Patel Shreya - - 2013
Uncuffed endotracheal tubes are still preferred over cuffed tubes in certain situations in pediatric anesthesia. Inaccurately sized uncuffed endotracheal tubes may lead to inadequate ventilation or tracheal mucosal damage during anesthesia. Endotracheal tube size in children is usually assessed by measuring the audible leak pressure; if the fit of the ...
Cedborg Anna I Hårdemark - - 2013
Intact pharyngeal function and coordination of breathing and swallowing are essential for airway protection and to avoid respiratory complications. Postoperative pulmonary complications caused by residual effects of neuromuscular-blocking agents occur more frequently in the elderly. Moreover, elderly have altered pharyngeal function which is associated with increased risk of aspiration. The ...
Kill Clemens - - 2013
Mechanical ventilation with an automated ventilator is recommended during cardiopulmonary resuscitation with a secured airway. We investigated the influence of intermittent positive-pressure ventilation, bilevel ventilation, and the novel ventilator mode chest compression synchronized ventilation, a pressure-controlled ventilation triggered by each chest compression, on gas exchange, hemodynamics, and return of spontaneous ...
Maitra Souvik - - 2013
Laryngeal mask airway (LMA) Supreme is a newly introduced single-use supraglottic device, which shares common features of both the LMA Pro-Seal and the intubating LMA (ILMA). Clinical studies have compared the safety and efficacy of the LMA Supreme over the 'gold standard' LMA Pro-Seal in different patient populations. However, the ...
Wilson Emily V - - 2013
Ventilation during neonatal resuscitation is typically initiated with a face mask, but may be ineffective due to leak or obstruction. To compare leak using three methods of mask hold. Medical and nursing staff regularly involved in neonatal resuscitation used the three holds (two-point, two-handed, spider) on a manikin in a ...
Sinderby Christer - - 2013
The aim of this study was to validate an automated, objective and standardized algorithm for quantifying and displaying patient-ventilator interaction. Using a new method to detect patient-ventilator synchrony, the present study re-analyzed previously acquired and published data from 24 mechanically ventilated adult patients (Colombo et al., Crit Care Med. 2011 ...
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