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Edwards Trenton T Division of Materials Science and Engineering, University of California at Davis, Davis, CA 95616, - - 2014
A fundamental mechanistic understanding of the pressure- and/or temperature-induced facile transformation of the coordination environment of boron is important for changing the physical properties of glass. We have used in situ high-pressure (up to 2 gigapascals) boron-11 solid-state nuclear magnetic resonance spectroscopy in combination with ab initio calculations to investigate ...
Wong Vivian V Vivian Wong, PhD, RN, CNS, CWON, Associate Professor, School of Nursing, San Jose State University, San Jose, - - 2014
The purpose of the study was to determine whether the interface pressure created when the heel is in contact with the bed surface reduced healthy adults' heel oxygen delivery (transcutaneous oxygen [TcO2]) and raised heel skin temperature. We also determined whether there was a hyperemic response to pressure relief on ...
Reiss Ido I Physics Department, Ben-Gurion University of the Negev, POB 653, Be'er-Sheva 84105, Israel and Physics Department, Nuclear Research Center Negev, POB 9001, Be'er-Sheva 84190, - - 2014
Tangential discontinuities, seen as x-ray edges known as cold fronts (CFs), are ubiquitous in cool-core galaxy clusters. We analyze all 17 deprojected CF thermal profiles found in the literature, including three new CFs we tentatively identify (in clusters A2204 and 2A0335). We discover small but significant thermal pressure drops below ...
Schuld J J Department of General--, Visceral--, Vascular-- and Paediatric Surgery, University of Saarland, Homburg/Saar, Germany - - - 2014
To compare healthy subjects and patients after total mesorectal excision concerning anal resting--/squeeze pressure and surface--electromyography of the sphincter. 40 patients (9 female/ 31 male) after total mesorectal excision due to low or middle rectal cancer were compared to a sex--, age-- and BMI-- matched group of healthy volunteers by ...
Sun Qijun Q SKKU Advanced Institute of Nanotechnology (SAINT), School of Chemical Engineering, Sungkyunkwan University, Suwon, 440-746, Republic of Korea; Department of Chemical Engineering, Pohang University of Science and Technology, Pohang, 790-784, Republic of - - 2014
A novel device architecture for preparing a transparent and low-voltage graphene pressure sensor matrix on plastic and rubber substrates is demonstrated. The coplanar gate configuration of the graphene transistor enables a simplified procedure. The resulting devices exhibit excellent device performance, including a high transparency of ∼80% in the visible range, ...
Abou El Ela Amal El Sayeh F AE Department of Pharmaceutics, Faculty of Pharmacy, King Saud University, Women Students - Medical Studies and Science Sections , Riyadh , Saudi Arabia - - 2014
Abstract The main aim of this work was to develop rectal suppositories for better delivery of metoprolol tartrate (MT). The various bases used were fatty, water soluble and emulsion bases. The physical properties of the prepared suppositories were characterized such as weight variation, hardness, disintegration time, melting range and the ...
Karakoyun Rojbin R *Department of Surgery, Antalya Training and Research Hospital, Antalya †Department of Surgery, Faculty of Medicine, Bozok University, Yozgat ‡Department of Surgery, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, - - 2014
Staple-line leak is a life-threatening complication of laparoscopic sleeve gastrectomy. Reinforcement materials have been reported to lower the risk of staple-line bleeding, but their effects on leak risk have not been elucidated. The aim of this study was to compare the effects of 2 supportive techniques on burst pressures in ...
Bracamonte José L JL Department of Large Animal Clinical Sciences, University of Saskatchewan, Saskatoon, Saskatchewan, - - 2014
To compare bursting strength, construction time, and anastomotic dimensions of 4 jejunoileal anastomotic techniques. Experimental ex vivo study. Adult horses (n = 12). Jejunoileal anastomoses were constructed from harvested ileal and distal jejunal segments using a single-layer Lembert technique (1HS), double-layer simple continuous/Cushing technique (2HS), stapled side-to-side technique (SS), or stapled functional ...
Paral Jiri J Department of Field Surger, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic. Electronic address: - - 2014
This study compared the resistance of glued versus stapled anastomosis of the colon to intraluminal pressures at different times during healing. Forty seven female domestic pigs, mean weight of 30.7 kg, were used. Maximum physiological luminal pressures, i.e. the pressure resisted by a catheter inserted into the intestinal lumen via ...
Wilhelm P P Working Group for Surgical Technology and Training, Clinic for General, Visceral and Transplant Surgery, Tübingen University Hospital, Waldhörnlestrasse 22, 72072, Tübingen, - - 2014
The aim of this study was to investigate the safety and efficacy of self-retaining barbed sutures in comparison with monofilament clip-fixated sutures for rectal wall closure in transanal endoscopic microsurgery. Horizontal full-thickness wall defects (3.5 cm) of cattle rectal specimens were closed via transanal endoscopic microsurgery using a monofilament suture with ...
Lee H J HJ Department of Gastroenterology, Asan Digestive Disease Research Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul, - - 2014
High-resolution manometry (HRM) based on spatiotemporal plots is increasingly being used. The aim this study was to evaluate, for the first time, the influence of gender, with adjustment for age, body mass index (BMI), and vaginal delivery, on anorectal functions in asymptomatic adults. Fifty-four asymptomatic healthy subjects (M : F = 27 : 27; age = 20-67 years) who ...
Liao Limin L Department of Urology, China Rehabilitation Research Center, Capital Medical University, 100068, Beijing, China, - - 2013
The aim of this study was to describe typical signal patterns (TSPs) by amplitude and pressure gradients and indicate the role and significance of them in quality control. A total of 582 measurements from a multicenter urodynamic study on males (mean age, 65.3 years) were re-analyzed. Using manual graphical analysis, we ...
Natoudi Maria M First Department of Propaedeutic Surgery, Hippokration Hospital, Athens Medical School Greece, 114 Queen's Sofia Avenue, Athens, - - 2013
Staple line leak, although rare, is among the most common postoperative complications after sleeve gastrectomy (SG) and usually occurs in the gastroesophageal (GE) junction. Increased intragastric pressure, regional ischemia, and technical failure of stapling devices have been reported as the main risk factors of postoperative leak. The aim of this ...
Lopez Julio J Department of Surgery, HGZ 35, Mexican Institute for Social Security , Juarez , - - 2013
Abstract Introduction: LigaSure™ was developed as an alternative to suture ligatures, hemoclips and staplers for ligating vessels and tissue bundles. The aim of the present study was to determine whether LigaSure can be used as a welding instrument in the performance of laparoscopic sleeve gastrectomy. Material and methods: Gastric specimens ...
Benezech Alban A Hôpital Nord, service de gastroentérologie, Marseille, - - 2013
Three-dimensional high-resolution anorectal manometry (3DHRAM) is a new technique that can simultaneously provide physiological and topographical data of the terminal part of the digestive tract. Our object was to assess whether 3DHRAM is able to reliably diagnose excesive perineal descent diagnosed with conventional defecography, which is considered to be the ...
Nelson Brad B - - 2013
To compare a unidirectional barbed suture (V-Loc™) to its suture material equivalent (Biosyn™) in a single-layer end-to-end anastomosis of equine jejunum. Experimental in vitro study. Jejunal sections from adult horses (n = 5) without gastrointestinal disease. Jejunal end-to-end anastomoses (n = 9) were performed for each group (V-Loc™, Biosyn™) with a continuous Lembert pattern ...
Bouguen G - - 2013
Transcutaneous electrical tibial nerve stimulation (TENS) is of growing interest for the treatment of fecal incontinence (FI), but its mechanism of action remains uninvestigated. We aimed to further assess the anorectal response to TENS in a dynamic model. We performed a placebo-controlled, randomized, double-blinded crossover study in 19 patients suffering ...
Gandini Marco - - 2013
To compare 4 techniques for pelvic flexure enterotomy closure in horses. Ex-vivo study. Cadaveric ascending colon specimens (n = 48 horses). Pelvic flexure enterotomies of different lengths (5 cm, 10 cm) were performed and closed with 1 of 4 techniques: handsewn 2 layer (HS2); handsewn 1 layer (HS1); skin staples (SKS); or TA90 stapling ...
Ratuapli S - - 2013
Defecatory disorders can be diagnosed by rectal balloon expulsion (BE) and anorectal manometry, which are traditionally evaluated in the seated and left lateral (LL) positions, respectively. The aims of this study were to compare BE in the LL and seated positions and to compare anorectal manometric parameters to BE performed ...
Emmertsen Katrine J - - 2013
To investigate neorectal properties regarding biomechanical, sensory and postprandial response in patients after TME without neoadjuvant radiotherapy in groups of No and Major LARS patients. Patients with No LARS (n=9) and Major LARS (n=23) were investigated by multimodal rectal stimulation and standard anorectal physiological tests, and results were compared. Patients ...
Otto Susanne D - - 2013
Anorectal manometry is used extensively in the assessment of patients with disorders of the pelvic floor. The present study investigated the repeatability of anorectal manometry in healthy volunteers and patients. A total of 30 healthy volunteers (15 men and 15 women) and 10 patients with fecal incontinence (4 men and ...
Yao Chunyan - - 2013
The relationship between membrane damage, leakage of intracellular compounds, and inactivation of Escherichia coli treated by pressurized CO2 was investigated by assessing the inactivation, bacterial cell membrane permeability, the leakage of protein, nucleic acid, and K(+) and Mg(2+) of E. coli. The results indicated that pressurized CO2 treatment induced the ...
Causey Marlin Wayne - - 2013
Many bariatric surgeons elect to pressure test the newly constructed staple lines in sleeve gastrectomy and duodenal switch procedures as a means of intraoperatively detecting leaks. The pressure tolerance of these fresh staple lines has not been well studied in a clinical setting. This is a retrospective institutional review board-approved ...
Lambe Tadhg - - 2013
Aim. The concept of compression alimentary anastomosis is well established. Recently, magnetic axial alignment pressures have been encompassed within such device constructs. We quantify the magnetic compression force and pressure required to successfully achieve gastrointestinal and bilioenteric anastomosis by in-depth interrogation of the reported literature. Methods. Reports of successful deployment ...
Ahn Ji Yong - - 2013
The pathophysiologic mechanism of rectal hyposensitivity (RH) is not well documented, and the significance of RH in biofeedback therapy (BFT) has not been evaluated. Thus, we aimed to assess the effect of BFT in constipated patients according to the presence of RH. Five hundred and ninety constipated patients (238 males ...
Leung Wing-Wa WW Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong 999077, China. - - 2013
To explore the effectiveness of acupuncture transcutaneous electrical nerve stimulation (Acu-TENS), a non-invasive modality in reduction of rectal discomfort during barostat-induced rectal distension. Forty healthy subjects were randomized to receive 45 min of either Acu-TENS or placebo-TENS (no electrical output) over acupuncture points Hegu (large-intestine 4), Neiguan (pericardium 6) and ...
Bajwa A - - 2013
INTRODUCTION: The barostat can be used to measure rectal sensitivity, compliance and elastance all of which are potentially important physiological parameters in the pathophysiology of faecal incontinence. Current practice recommends a conditioning distension sequence be performed prior to index distensions. We questioned the validity of this by comparing values for ...
Ratuapli Shiva K SK Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, - - 2013
Disordered defecation is attributed to pelvic floor dyssynergia. However, clinical observations indicate a spectrum of anorectal dysfunctions. The extent to which these disorders are distinct or overlap is unclear; anorectal manometry might be used in diagnosis, but healthy persons also can have abnormal rectoanal pressure gradients during simulated evacuation. We ...
Heinrich H - - 2012
Background  Guidelines recommend instruction and motivation during anorectal manometry; however, its impact on findings has not been reported. This study assessed the effects of standard versus enhanced instruction and verbal feedback on the results of anorectal manometry. Methods  High-resolution manometry was performed by a solid-state catheter with 10 circumferential sensors ...
Dhaun Neeraj - - 2012
Since its discovery over 20 years ago endothelin-1 (ET-1) has been implicated in a number of physiological and pathophysiological processes. Its role in the development and progression of chronic kidney disease (CKD) is well established and is an area of ongoing intense research. There are now available a number of ...
Noelting Jessica J Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, - - 2012
High-resolution manometry (HRM) is used to measure anal pressures in clinical practice but normal values have not been available. Although rectal evacuation is assessed by the rectoanal gradient during simulated evacuation, there is substantial overlap between healthy people and defecatory disorders, and the effects of age are unknown. We evaluated ...
Callaghan Brid - - 2012
Circulating ghrelin reduces blood pressure but the mechanism for this action is unknown. This study investigated whether ghrelin has direct vasodilator effects mediated through the growth hormone secretagogue receptor 1a (GHSR1a) and whether ghrelin reduces sympathetic nerve activity. Mice expressing enhanced green fluorescent protein under control of the promoter for ...
Foulquier Sébastien - - 2012
It is now widely accepted that the angiotensin AT(2) receptor (AT(2)R) plays an important protective role during pathophysiologic conditions, acting as a repair system. The development of the first selective nonpeptide AT(2)R agonist C21 accelerated our understanding of AT(2)R-mediated protective signaling and actions. This article reviews the impact of C21 ...
Kim K - - 2012
In this study, we hypothesized that haptic feedback would enhance grip force control of sEMG-controlled prosthetic hands for Targeted Reinnervation amputees. A new miniature haptic device..a tactor..that can deliver touch, pressure, shear, and temperature sensation, allows modality-matching haptic feedback. Targeted Reinnervation (TR) surgery that creates sensory regions on the patients ...
Kerr Eve A - - 2012
Performance measures that reward achieving blood pressure (BP) thresholds may contribute to overtreatment. We developed a tightly linked clinical action measure designed to encourage appropriate medical management and a marker of potential overtreatment, designed to monitor overly aggressive treatment of hypertension in the face of low diastolic BP. We conducted ...
Rosser Julie M - - 2012
Our objective was to compare thoracoabdominal (TA Premium™ 90) stapled enterotomy closure to traditional hand-sewn closure, using time to perform the technique, luminal diameter, and bursting pressure in ex-vivo specimens. The pelvic flexures of 13 client-owned horses were harvested. Each pelvic flexure had 1 enterotomy performed; 6 were closed via ...
Klimas Jan - - 2012
Antihypertensive treatment may reduce prolonged QT duration in hypertension. Generally, the reductions of blood pressure and/or of cardiac mass are believed to be the responsible factors. However, drugs are not equivalent in QT modulation despite similar antihypertensive and antihypertrophic action. We investigated the effect of a calcium channel blocker, lacidipine ...
Watts Stephanie W - - 2012
5-Hydroxytryptamine (5-HT; serotonin) was discovered more than 60 years ago as a substance isolated from blood. The neural effects of 5-HT have been well investigated and understood, thanks in part to the pharmacological tools available to dissect the serotonergic system and the development of the frequently prescribed selective serotonin-reuptake inhibitors. ...
Ayala Carma - - 2012
We examined the prevalence of actions taken to control blood pressure as measured by taking antihypertensive medication or making lifestyle modifications among hypertensive adults residing along the Texas/Mexico border. We used self-reported data from the 2007 Texas Behavioral Risk Factor Surveillance System, with oversampling of border counties. We calculated the ...
Schmid-Schönbein Geert W - - 2012
One of the major challenges for hypertension research is to identify the mechanisms that cause the comorbidities encountered in many hypertensive patients, as seen in the metabolic syndrome. An emerging body of evidence suggests that human and experimental hypertensives may exhibit uncontrolled activity of proteinases, including the family of matrix ...
Cunha Ana Rosa - - 2012
Many factors have been implicated in the pathogenesis of hypertension, including changes in intracellular concentrations of calcium, sodium, potassium, and magnesium. There is a significant inverse correlation between serum magnesium and incidence of cardiovascular diseases. Magnesium is a mineral with important functions in the body such as antiarrhythmic effect, actions ...
Fabrizi Francesca - - 2011
The clinically used sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitor dorzolamide (DRZ), a new sulfonamide CA inhibitor also incorporating NO-donating moieties, NCX250, and isosorbide mononitrate (ISMN) (an NO-donating compound with no CA inhibitory properties) were investigated for their intraocular pressure (IOP) lowering effects in rabbits with carbomer-induced glaucoma. NCX250 was ...
Muramalla T - - 2011
Lactobacillus delbrueckii ssp. bulgaricus, Streptococcus salivarius ssp. thermophilus, and Lactobacillus acidophilus are dairy cultures widely used in the manufacture of cultured dairy products. Commonly used homogenization pressures in the dairy industry are 13.80 MPa or less. It is not known whether low homogenization pressures can stimulate bacteria to improve their ...
Yannopoulos Demetris D Department of Medicine, University of Minnesota, Minneapolis-St. Paul, MN, USA. - - 2011
To assess the effectiveness of sodium nitroprusside (SNP)-"enhanced" cardiopulmonary resuscitation (SNPeCPR) on 24-hr survival rates compared to standard CPR in animals after cardiac arrest. SNPeCPR consists of large intravenous SNP bolus doses during CPR enhanced by active compression-decompression CPR, an inspiratory impedance threshold device (ITD), and abdominal binding (AB). The ...
Elstad Maja - - 2011
OBJECTIVE: Cardiovascular variability is a complex physiological phenomenon associated with the outcome of cardiovascular diseases. Blood pressure oscillations may cause cardiovascular complications, which, however, are also claimed to have antihypertensive effects. The physiological understanding is limited. This study evaluates whether oscillations in heart rate (HR) and cardiac output (CO) buffer ...
Fu Yong-Nan - - 2011
Aim:To identify the role of metformin in cardiac hypertrophy and investigate the possible mechanism underlying this effect.Methods:Wild type and AMPKα2 knockout (AMPKα2(-/-)) littermates were subjected to left ventricular pressure overload caused by transverse aortic constriction. After administration of metformin (200 mg·kg(-1)·d(-1)) for 6 weeks, the degree of cardiac hypertrophy was ...
Silvani Alessandro - - 2011
The cross-correlation function (CCF) yields the correlation coefficient between spontaneous fluctuations of heart period and blood pressure as a function of the time shift between these variables. Two CCF patterns occur in humans: I) positive correlation between heart period and previous pressure values; II) negative correlation between heart period and ...
Valezi Antonio Carlos - - 2011
BACKGROUND: This study aims to evaluate the effect of weight loss on the physical capacity and the structure and function of the heart after bariatric surgery. METHODS: Forty-three adult obese patients, 31 women (72.1%) and 12 men (27.9%), were submitted to electrocardiogram, ergometric test, and echo Doppler cardiogram at presurgical ...
Yadid Moran - - 2011
The heart accommodates to rapid changes in demands. This review elucidates the adaptive control of cardiac function by loading conditions, and integrates the sarcomeric control of contraction (SCC) with isolated trabeculae and in vivo whole-heart studies. The SCC includes two feedback mechanisms: (1) cooperativity that regulates cross-bridge (XB) recruitment and ...
Saleh Hesham Z - - 2011
The optimum method of intraoperative monitoring in patients undergoing off-pump coronary bypass remains debatable. Using capnography and end-tidal carbon dioxide pressure may be a helpful method of monitoring cardiac output trends, especially when grafting posterior and lateral vessels. After repositioning the heart, End-tidal carbon dioxide pressures that continue to trend ...
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