Search Results
Results 1 - 50 of 1243
1 2 3 4 5 6 7 8 9 10 >
Park So Yon SY Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul, - - 2014
Hypertension is the most prevalent cardiovascular disease worldwide, but its genetic basis is poorly understood. Recently, genome-wide association studies identified 33 genetic loci that are associated with blood pressure. However, it has been difficult to determine whether these loci are causative owing to the lack of functional analyses. Of these ...
Riccó Carolina H CH Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA - - 2014
Objective-To compare the hemodynamic responses to orotracheal intubation following induction of anesthesia with propofol, ketamine-propofol, and ketamine-diazepam in premedicated dogs. Design-Prospective, randomized, masked study. Animals-10 healthy adult Beagles. Procedures-Dogs were randomly allocated to be anesthetized twice, with a 1-week wash-out interval, by means of 2 of 3 possible protocols (propofol ...
Aarnes Turi K TK Department of Veterinary Clinical Sciences, The Ohio State University College of Veterinary Medicine, Columbus, Ohio 43210, - - 2014
The objective of this study was to compare recovery from desflurane anesthesia in horses with or without post-anesthetic xylazine. Six adult horses were anesthetized on 2 occasions, 14 d apart using a prospective, randomized crossover design. Horses were sedated with xylazine, induced to lateral recumbency with ketamine and diazepam, and ...
Graham M Ruth MR Department of Anesthesia, University of Manitoba, Winnipeg, MB, Canada, - - 2014
The dynamic change in arterial pulse pressure during mechanical ventilation (PPV) predicts fluid responsiveness in adults but may not be applicable to pediatric patients. We compared PPV during hemorrhage and reinfusion in immature vs mature piglets at two clinically relevant tidal volumes (VT). Following Institutional Animal Care Committee approval, we ...
Scott Victoria H VH Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH - - 2014
Objective-To assess effects of body position on direct measurements of intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP) in horses anesthetized with total intravenous anesthesia (TIVA). Animals-9 healthy adult horses. Procedures-Instrumentation in unsedated standing horses involved insertion of an arterial catheter for blood pressure measurements and 3 intraperitoneal cannulas (left ...
Kim Min-Soo MS Yonsei University College of Medicine, Department of Anesthesiology and Pain Medicine, and Anesthesia and Pain Research Institute, Seoul, Korea, Republic of ; - - 2014
Purpose: The purpose of this study was to assess the extent of the increased intracranial pressure (ICP) resulting from carbon dioxide (CO2) pneumoperitoneum and steep Trendelenburg positioning using ultrasonographic measurement of optic nerve sheath diameter (ONSD) in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP). Methods: Twenty patients who underwent elective ...
Wang Qun Q Department of Anesthesiology, Wuxi Maternity and Child Health Hospital Affiliated to Nanjing Medical University, Wuxi, - - 2014
Objective The aim of the article was to investigate the effect of ondansetron preloading with crystalloid infusion after spinal anesthesia during cesarean delivery. Study Design A total of 66 parturient women scheduled for elective caesarean sections were randomly assigned to two groups. Five minutes before spinal anesthesia, Group O patients were injected ...
Chima Ranjit S RS Texas Tech University Health Sciences Center, Lubbock, TX, - - 2014
An anesthesiologist must remain vigilant of the patient's clinical status, incorporating many independent physiological measurements. Oxygen saturation and heart rate are represented by continuous audible tones generated by the pulse oximeter, a mandated monitoring device. Other important clinical parameters-notably blood pressure-lack any audible representation beyond arbitrarily-configured threshold alarms. Attempts to ...
Möller Johannes J Fakultät Physik/DELTA, TU Dortmund, 44221 Dortmund, - - 2014
We present results from small-angle x-ray scattering data on the effect of high pressure on the phase behavior of dense lysozyme solutions in the liquid-liquid phase separation region, and characterize the underlying intermolecular protein-protein interactions as a function of temperature and pressure in this region of phase space. A reentrant ...
Zhang Ying Y Shanghai Jiading Central Hospital, Department of Anesthesiology, Shanghai, - - 2014
To investigate a saddle anesthesia with different doses of chloroprocaine in perianal surgery. Total 60 Patients aged 18-75 years (Anesthesiologists grade I or II) scheduled to receive perianal surgery. Patients using saddle anesthesia were randomized to group A, group B and group C with the same concentration (0.5%) chloroprocaine with ...
Oshvandi Khodayar K Department of Nursing, Research Center for Maternal and Child Care, Hamadan, - - 2014
Hypothermia is one of the problems occurring during surgery, which can happen due to thermoregulation mechanism disorders and intake of low temperature IV fluids, and may cause increase in blood pressure, heart rate, intracranial pressure, oxygen consumption, pain, and discomfort to the patient. The rate of cesarean section in our ...
Li Aihua A Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth Lebanon, NH, - - 2014
In this review we focus on the role of orexin in cardio-respiratory functions and its potential link to hypertension. (1) Orexin, cardiovascular function, and hypertension. In normal rats, central administration of orexin can induce significant increases in arterial blood pressure (ABP) and sympathetic nerve activity (SNA), which can be blocked ...
Modi M P MP Department of Anaesthesia and Critical Care, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases and Research Centre and Dr. H. L. Trivedi Institute of Transplantation Sciences, Asarwa, Ahmedabad, Gujarat, - - 2014
In this retrospective study, we describe the anesthetic management and its implications in parturients with chronic kidney disease (CKD; n = 9), who underwent elective caesarean delivery. Nine parturients with CKD of various etiologies, who underwent elective Caesarean delivery, were included in this study. Spinal anest-hesia was administered in all ...
Foss Visti T VT Department of Anaesthesia, Næstved Hospital Næstved, - - 2014
Background: During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients exposed to spinal anesthesia is not known. Objectives: To ...
Lu Wenqing W Department of Anesthesiology, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China - - 2014
Background The pleth variability index (PVI) has been demonstrated to be a useful, noninvasive indicator of continuous fluid responsiveness. Whether PVI can be used to assess the changes of intravascular volume status remains to be elucidated. Material and Methods Using correlation analysis and receiver operating characteristic (ROC) curves, we sought ...
Zhang Lieliang L Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China - - 2014
Background Although photoplethysmography and cerebral state index (CSI) have been used as indices in monitoring vital signs perioperatively, there are only a few reports comparing the performance of photoplethysmography with CSI in monitoring anaesthesia depth. The aim of the present study was to clarify features of photoplethysmography in monitoring balanced ...
Vargas M M Department of Neurosciences and Reproductive and Odontostomatological Sciences, University of Naples "Federico II," 80100 Naples, - - 2014
Positive end expiratory pressure (PEEP) may prevent cyclic opening and collapsing alveoli in acute respiratory distress syndrome (ARDS) patients, but it may play a role also in general anesthesia. This review is organized in two sections. The first one reports the pathophysiological effect of PEEP on thoracic pressure and hemodynamic ...
Araújo Marcelo A MA Department of Veterinary Medicine, Faculty Integrated, Campo Mourão, PR, - - 2013
To assess the cardiovascular changes of a continuous rate infusion of lidocaine in calves anesthetized with xylazine, midazolam, ketamine and isoflurane during mechanical ventilation. Prospective, randomized, cross-over, experimental trial. A total of eight, healthy, male Holstein calves, aged 10 ± 1 months and weighing 114 ± 11 kg were included in the study. Calves were administered ...
Postma Ineke R IR Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The - - 2013
Objective Neuraxial anesthesia is known to reduce sympathetic tone and mean arterial pressure. Effects on cerebral hemodynamics in pregnancy are not well known. We hypothesize that cerebral hemodynamic parameters will change with respect to baseline following regional analgesia/anesthesia. Study Design We performed maternal transcranial Doppler of the middle cerebral artery in 20 ...
Siddik-Sayyid Sahar M - - 2013
Phenylephrine infusion is used to reduce hypotension during spinal anesthesia for cesarean delivery. A prophylactic fixed rate infusion regimen may not improve hemodynamic control; a variable rate regimen adjusted in response to changes in arterial blood pressure and heart rate may allow more accurate maintenance of baseline blood pressure. We ...
Napier Julia E JE Omaha's Henry Doorly Zoo and Aquarium, 3701 South 10th Street, Omaha, Nebraska 68107, USA. - - 2013
Until the majority of the great ape population is trained for conscious cardiac evaluations, most individuals will require general anesthesia to perform echocardiograms. Within the veterinary community, concern exists that certain anesthetic protocols may exacerbate or artificially induce signs of cardiac disease. Because of potential cardiovascular effects, medetomidine has generally ...
Ozgul Ulku U Department of Anesthesiology and Reanimation, School of Medicine, Inonu University, Malatya, - - 2013
The aim of our study is to compare the effect of ketamine-propofol mixture (ketofol) and propofol on the laryngeal tube-Suction II (LTS II) insertion conditions and hemodynamics. Eighty American Society of Anesthesiologists class 1 and 2 patients were divided into 2 random groups to receive either 1 µg/kg remifentanil and ...
Alkenany Hatem M Nasr - - 2013
This study evaluated and explored time course, efficacy, relation, safety, changes in heart rate, and blood pressure after a bolus dose of sugammadex or neostigmine for reversal of a prolonged rocuronium and vecuronium induced neuromuscular block. A total of 60 patients of both sexes, 'ASA' grade I, II and all ...
Scarparo Henrique Clasen - - 2013
Cardiovascular effects of epinephrine, especially on blood pressure (BP) and heart rate (HR), have been well documented. When present in dental local anesthetic solutions, epinephrine concentration ranges from 5 to 20 µg/mL. Doses less than 200 µg are recommended to be clinically safe. This study investigated the effects of the ...
Gianesello Lara - - 2013
A hemodynamic event such as hypertension after interscalene block (ISB) is a complication that is often overlooked. The irregular spread of local anesthetic would cause a blockade of carotid sinus baroreceptors leading to the adverse event. The purpose of the present study is to compare ultrasound and neurostimulation technique in ...
Nair Bala G - - 2013
Intraoperative hypotension and hypertension are associated with adverse clinical outcomes and morbidity. Clinical decision support mediated through an anesthesia information management system (AIMS) has been shown to improve quality of care. We hypothesized that an AIMS-based clinical decision support system could be used to improve management of intraoperative hypotension and ...
Aarnes Turi K - - 2013
To determine the level of agreement between an oscillometric (O-NIBP) and an invasive method (IBP) of monitoring arterial blood pressure (ABP) in anesthetized sheep, goats, and cattle. Prospective clinical study. Twenty sheep and goats, 20 cattle weighing <150 kg body weight, and 20 cattle weighing >150 kg body weight. Animals were anesthetized ...
Wolf Andrew R AR Department of Paediatric Intensive Care, Bristol Royal Children's Hospital, Bristol, UK; Department of Paediatric Anaesthesia, Bristol Royal Children's Hospital, Bristol, - - 2014
Development of the cardiovascular system through the last trimester of pregnancy and the subsequent neonatal period is profound. Morphological changes within the myocardium make the heart vulnerable to challenges such as fluid shifts and anesthetic drugs. The sensitivity of the myocardium to metabolic challenges and potential harm of drugs needed ...
Kijtawornrat Anusak - - 2013
The evaluation of proarrhythmic and hemodynamic liabilities for new compounds remains a major concern of preclinical safety assessment paradigms. Contrastingly, albeit functional liabilities can also translate to clinical morbidity and mortality, lesser preclinical efforts are focused on the evaluation of drug-induced changes in inotrope and lusitrope, particularly in the setting ...
Degerli Semih - - 2013
The effects of different body positions on the middle ear were reported in several studies, but there are no data about the effects on patients under general anesthesia. The aim of this study is to determine the effect of prone position on middle ear pressure (MEP) during general anesthesia without ...
Grap Mary Jo - - 2013
To determine the effect of sedation on physiologic responses and comfort before, during and after a noxious stimulus (endotracheal tube suctioning). The sample was a subset of a larger, longitudinal descriptive study, blood for endorphins and saliva for alpha-amylase were obtained before and after suctioning. Heart rate (HR), respiration rate ...
Tran Khoa - - 2013
We evaluated the effect of propofol on resting anal sphincter pressure (RP) during anorectal manometry (ARM) performed under general anesthesia in 20 children with chronic constipation. After propofol bolus administration, there was a significant decrease in the RP in 95% of subjects from a mean of 51.5 ± 15.3 mmHg to a ...
Severinghaus John W - - 2013
After training in physics during World War II, I spent 2 years designing radar at Massachusetts Institute of Technology and then switched to biophysics. After medical school and a residency, I was doctor drafted to National Institutes of Health where I studied blood gas transport in hypothermia and developed the ...
Kweon Tae Dong - - 2013
Hypotension is a common phenomenon after spinal anesthesia in hypertensive patients. We investigated whether heart rate variability could predict the occurrence of hypotension after spinal anesthesia in hypertensive patients. Forty-one patients undergoing spinal anesthesia were included. Heart rate variability was measured at five different time points such as before fluid ...
Masoudifar Mehrdad M Department of Anesthesiology, Kashani Hospital, Isfahan, - - 2013
Most neurosurgeons and anesthesiologists prefer the less invasive intervention for most surgeries; recently, the lumbar anesthesia is more popular method. In this study we have tried to distract the attention of the patients to their favorite video-clip instead of their surrounding operating room background to evaluate the hemodynamic as well ...
Masoudifar Mehrdad M Department of Anesthesiology, Ayatolah Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, - - 2013
Etomidate and Propofol are common anesthetic agents. Previous studies say that Etomidate can be used in patients with limited hemodynamic reserve and Propofol can lead to more hemodynamic instabilities. This study was performed to explore the cardiovascular response during the induction of anesthesia with Etomidate or for comparison, Propofol in ...
Chan Wei-Hung - - 2013
To investigate whether a target-controlled infusion (TCI) with propofol, a method having theoretically better control of drug concentration, would produce less cardiovascular and respiratory suppression than intermittent bolus of a sedative-analgesic cocktail regimen in deep sedation for gastrointestinal endoscopy. One hundred participants underwent esophagoduodenoscopy (EGD) and 120 underwent colonoscopy were ...
Ioannou Christos V - - 2013
To investigate the effect of general anesthesia on aortic compliance and other cardiovascular hemodynamics in chronically instrumented pigs with compliant and noncompliant (stiff) aortas. Experimental study. University animal laboratory. Twelve adult Yucatan miniature pigs. Chronic instrumentation of a compliant (control; n = 7) and noncompliant (n = 5) group to ...
Bencze M - - 2013
Most anesthetics induce characteristic hemodynamic changes leading to blood pressure (BP) reduction but the role of renin-angiotensin system (RAS), sympathetic nervous system (SNS) and nitric oxide (NO) synthesis in this BP reduction is unknown. We therefore studied the influence of four widely used anesthetics - pentobarbital (P), isoflurane (ISO), ketamine-xylazine ...
Riphaus A - - 2013
Background and study aims: The use of sedation (e. g., of short-acting propofol) for gastrointestinal endoscopy has shown an upward trend in the USA and Europe over the last decade. To improve patient's safety different nationwide guidelines have been developed. This survey aimed at providing nationwide re-evaluated data 3 years ...
Kinney Matthew E - - 2013
Dexmedetomidine, a highly selective alpha-2 adrenergic agonist and dextrorotary enantiomer of medetomidine, was combined with ketamine and used to immobilize 14 free-ranging Choloepus hoffmanni (Hoffmann's two-toed sloths) and 11 Bradypus variegatus (brown-throated three-toed sloths) in Upala, Costa Rica. Following intramuscular injection of ketamine (2.1 mg/kg) and dexmedetomidine (11 microg/kg), heart ...
Vaschetto Rosanna - - 2013
Evaluating the physiologic effects of varying depths of propofol sedation on patient-ventilator interaction and synchrony during pressure support ventilation and neurally adjusted ventilatory assist. Prospective crossover randomized controlled trial. University hospital ICU. Fourteen intubated patients mechanically ventilated for acute respiratory failure. Six 25-minute trials randomly performed applying both pressure support ...
Chiarandini Paolo - - 2013
The aim of this study was to investigate the effects of clinical dosages of norepinephrine and dobutamine on sublingual microcirculation during general anesthesia with sevoflurane in minor surgical procedures. This prospective study was performed on patients scheduled for breast cancer surgery. Tertiary care university hospital. Twenty patients undergoing elective surgery. ...
Abutarboush Rania - - 2013
Hemoglobin-based oxygen carrier-201 (HBOC) was developed as a resuscitative fluid but concerns exist over potentially adverse vasoconstriction. This study evaluated whether concurrent IV N-acetyl-L-cysteine (NAC) or hyaluronic acid (HA) would attenuate HBOC-associated vasoconstriction, assessed by systemic blood pressures and cerebral pial microvasculature, when administered to healthy, anesthetized rats. Rats (8-9/group) ...
Wu Jing - - 2013
Epinephrine was recently shown to induce a hypotension episode. Activation of β2-adrenoceptors with smooth muscle relaxation may be the underlying mechanism. This study investigated the effects of ICI 118551, a β2-adrenoceptors antagonist, on epinephrine-induced blood pressure reduction via different administration routes in rats. A total of 144 Sprague-Dawley rats were ...
Park Sang-Jin - - 2013
Jaw-thrust is a noxious stimulus that might induce sympathetic responses. The purpose of this study, was to evaluate the effects of jaw-thrust on sympathetic responses. We investigated seventy three patients. Patients who received general anesthesia were randomly divided into a control group (maintenance of combined airway maneuver with head tilt, ...
Moorer Jeremiah D - - 2013
A blinded, prospective, randomized crossover study was performed to determine the effects of ampicillin Na/sulbactam Na and enrofloxacin on the blood pressure (BP) of healthy anesthetized dogs. Eight dogs were anesthetized three different times. They randomly received enrofloxacin, ampicillin Na/sulbactam Na, and saline. Systolic, diastolic, and mean arterial BPs (SAP, ...
Ambrósio Aline M - - 2013
To assess if positive end-expiratory pressure (PEEP) titration improves gas exchange and respiratory mechanics, without hemodynamic impairment in horses during anesthesia. Prospective, randomized study. Thirteen isoflurane-anesthetized healthy horses. After 60 minutes of anesthesia with spontaneous breathing, mechanical ventilation was initiated with an inspiratory-expiratory ratio of 1:2, PEEP of 5 cmH2 O, ...
Iwayama Sachiko - - 2013
Despite the implementation of liberal preoperative fasting routines, it is unclear whether preoperative oral rehydration solution intake volume affects blood pressure during general anesthesia. We enrolled 60 patients (American Society of Anesthesiologists status I/II) undergoing tympanoplasty. Patients drank 200-1,000 ml oral rehydration solution until 2-3 h before anesthesia induction. Anesthesia was induced ...
Yu Tao - - 2013
Hypotension due to the induction of sedation with dexmedetomidine infusion may be harmful in critically ill patients. Changes in pulse pressure induced by the passive leg raising test (PLR-ΔPP) as marker of fluid responsiveness, assessed prior to sedation, may predict hemodynamic changes. The present study was to investigate the power ...
1 2 3 4 5 6 7 8 9 10 >