Search Results
Results 301 - 350 of 1270
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Siebenhofer Andrea A Department of Internal Medicine and Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Auenbruggerplatz 15, Graz, Austria, - - 2009
All major guidelines for antihypertensive therapy recommend weight loss; anti-obesity drugs might be a helpful option. To assess the long-term effects of pharmacologically induced reduction in body weight with orlistat, sibutramine or rimonabant on:- all cause mortality - cardiovascular morbidity - adverse events - changes in systolic and/or diastolic blood ...
Williams Bryan - - 2009
BACKGROUND: Statins reduce the risk of cardiovascular events in people with hypertension. This benefit could arise from a beneficial effect of statins on central aortic pressures and hemodynamics. The Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) study, an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy, investigated this hypothesis in a prospective placebo-controlled ...
Greenfield Jerry R JR University of Cambridge Metabolic Research Laboratories, Addenbrooke's Hospital, Cambridge, United - - 2009
Weight gain and weight loss are associated with changes in blood pressure through unknown mechanisms. Central melanocortinergic signaling is implicated in the control of energy balance and blood pressure in rodents, but there is no information regarding such an association with blood pressure in humans. We assessed blood pressure, heart ...
Potter John F JF School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK. - - 2009
Raised blood pressure is common after acute stroke and is associated with an adverse prognosis. We sought to assess the feasibility, safety, and effects of two regimens for lowering blood pressure in patients who have had a stroke. Patients who had cerebral infarction or cerebral haemorrhage and were hypertensive (systolic ...
Zhang John - - 2008
This study reports on the effects of laser acupuncture on blood pressure, body weight, and heart rate variability by stimulating acupuncture points and meridians on college students and faculty members. Forty-five students and faculty members from a chiropractic college were recruited in the study. All subjects signed a written informed ...
Vinyoles Ernest - - 2008
BACKGROUND AND AIMS: The aim of the COGNIPRES study was to analyze the prevalence of cognitive impairment in hypertensive individuals over 60 years of age, treated in primary care centres in the context of routine clinical practice. Degree of blood pressure control and treatment compliance, as well as other possible ...
Azar Ahmad Taher - - 2008
On-line monitoring devices to control functions such as volume, body temperature, and ultrafiltration, were considered more toys than real tools for routine clinical application. However, bio-feedback blood volume controlled hemodialysis (HD) is now possible in routine dialysis, allowing the delivery of a more physiologically acceptable treatment. This system has proved ...
Wojciechowski David - - 2008
An observational study was conducted in 164 patients with resistant or difficult-to-control hypertension. Treatment was adjusted to achieve blood pressure recommendations from the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7). Patients were mostly male (95.73%) and African American ...
Hersch Moshe - - 2008
STUDY OBJECTIVES: To investigate the effect of intravenous propacetamol, a parenteral bioprecursor of acetaminophen, on systemic blood pressure in critically ill patients with fever, and to establish the prevalence and clinical significance of this effect. DESIGN: Prospective, observational study. SETTING: A six-bed medical-surgical intensive care unit (ICU) of a university-affiliated ...
Shindo Yuichiro - - 2008
BACKGROUND AND OBJECTIVE: The initial assessment of the severity of community-acquired pneumonia (CAP) is important for patient management. The Japanese Respiratory Society (JRS) has proposed a 6-point scale (0-5) to assess the clinical severity of CAP. The A-DROP scoring system assesses the following parameters: (i) Age (male >or= 70 years, ...
Grassi Daniel - - 2008
To study the efficacy of a treatment strategy for the management of hypertensive urgencies, the authors evaluated 549 patients admitted to the emergency department. They were first assigned to a 30-minute rest period, then a follow-up blood pressure measurement was carried out. Patients who did not respond to rest were ...
Zsom Lajos - - 2008
Decades after the introduction of chronic maintenance hemodialysis, the optimal means of quantifying dialysis dose remains controversial. Differences of opinion in the international dialysis community lead to substantial diversity in everyday clinical practice. Several studies suggest that the well-recognized international mortality differences in hemodialysis populations may result from these divergent ...
Morales José M - - 2008
Results at 1 year of a pilot randomized trial with 87 kidney graft recipients, comparing the maintenance treatment with sirolimus, tacrolimus and steroids (group I) versus tacrolimus withdrawal since the third month onward, followed by maintenance with SRL and steroids (group II) have shown that early elimination of tacrolimus may ...
Feig Daniel I DI Department of Pediatrics, Renal Section, Baylor College of Medicine, Houston, TX 77030, USA. - - 2008
Hyperuricemia is a predictor for the development of hypertension and is commonly present in new-onset essential hypertension. Experimentally increasing uric acid levels using a uricase inhibitor causes systemic hypertension in animal models. To determine whether lowering uric acid lowers blood pressure (BP) in hyperuricemic adolescents with newly diagnosed hypertension. Randomized, ...
Aronow Wilbert S - - 2008
Hypertension in a nursing home patient is a systolic blood pressure of 140 mm Hg or higher and 130 mm Hg or higher in a patient with diabetes mellitus or chronic renal insufficiency, or a diastolic blood pressure of 90 mm Hg or higher and 80 mm Hg or higher ...
Mullens Wilfried - - 2008
OBJECTIVES: This study was designed to examine the safety and efficacy of sodium nitroprusside (SNP) for patients with acute decompensated heart failure (ADHF) and low-output states. BACKGROUND: Inotropic therapy has been predominantly used in the management of patients with ADHF presenting with low cardiac output. METHODS: We reviewed all consecutive ...
Hooper Lee - - 2008
BACKGROUND: The beneficial effects of flavonoid consumption on cardiovascular risk are supported by mechanistic and epidemiologic evidence. OBJECTIVE: We aimed to systematically review the effectiveness of different flavonoid subclasses and flavonoid-rich food sources on cardiovascular disease (CVD) and risk factors--ie, lipoproteins, blood pressure, and flow-mediated dilatation (FMD). DESIGN: Methods included ...
Ofili Elizabeth O - - 2008
This post hoc analysis of the Irbesartan/Hydrochlorothiazide Blood Pressure Reductions in Diverse Patient Populations (INCLUSIVE) trial evaluated the efficacy and safety of irbesartan/hydrochlorothiazide (HCTZ) in a diverse population of hypertensive women. INCLUSIVE was a multicenter, prospective, open-label, single-arm trial. Adult subjects had uncontrolled systolic blood pressure (SBP 140-159 mm Hg; ...
Dickinson Ho - - 2008
The objective of this review was to evaluate the effectiveness of relaxation to lower high blood pressure. We searched electronic bibliographic databases and grey literature to identify randomized controlled trials comparing relaxation therapies with no active treatment or sham therapy, enrolling adult participants with raised systolic blood pressure (SBP) > ...
Baumann Brigitte M - - 2008
OBJECTIVE: This study examined the variability of blood pressure measurements and prevalence estimates of elevated blood pressure in emergency department (ED) patients using 4 different methods of categorization. METHODS: A prospective, observational study was conducted on adult ED patients with elevated triage blood pressures (systolic > or = 140 or ...
Thase Michael E - - 2008
The effects of bupropion on blood pressure and heart rate were evaluated in a double-blind, placebo-controlled study of community volunteers with untreated mild (stage 1) hypertension (systolic blood pressure [SBP], 140-159 mm Hg, and/or diastolic blood pressure, 90-99 mm Hg). Three hundred subjects were randomly assigned (1:1:1:1) to 4 weeks ...
Jonas W - - 2008
BACKGROUND AND AIMS: The benefits of breastfeeding for infants are well known. Recently data have started to emerge showing that breastfeeding may also induce positive effects in the mother. This study aimed to investigate the pattern of maternal blood pressure before, during, and after a breastfeed 2 days postpartum. Additionally, ...
Kerr Eve A EA Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System and the University of Michigan Department of Internal Medicine, Ann Arbor, Michigan 48113-0170, USA. - - 2008
Factors underlying failure to intensify therapy in response to elevated blood pressure have not been systematically studied. To examine the process of care for diabetic patients with elevated triage blood pressure (> or =140/90 mm Hg) during routine primary care visits to assess whether a treatment change occurred and to ...
Farese Stefan - - 2008
BACKGROUND: Intradialytic exercise has been described to improve blood pressure stability and dialysis efficacy. However, comorbid conditions in the dialysis population often preclude the widespread use of active intradialytic exercise. Therefore, we investigated the effect of intradialytic transcutaneous muscle stimulation (TEMS) and passive cycling movements (PCMs) on blood pressure and ...
Millar Philip J - - 2008
PURPOSE: Research has demonstrated the efficacy of isometric handgrip (IHG) training to attenuate resting blood pressure. These studies have relied on the use of programmable digital handgrips for training. This study aimed to determine the effectiveness of simple, inexpensive spring-loaded handgrip devices in producing hypotensive effects. METHODS: The study was ...
Acar Banu - - 2008
BACKGROUND: The adverse effects of peritonitis and of the duration of dialysis on dialysis adequacy and clinical outcome were evaluated in this study. METHODS: The study comprised 24 chronic peritoneal dialysis patients who were followed up at least for 12 months. Casual blood pressure (BP) measurements, echocardiographic evaluation, peritonitis rate, ...
Wills Brandon K - - 2010
Calcium channel blocker (CCB) overdose is associated with dysrhythmias and atrioventricular (AV) block, however, experience with infant CCB overdose is limited. A 9-month-old girl was found playing with tablets of extended-release diltiazem 120 mg. The patient had two episodes of emesis, which contained pill fragments, and was brought to the ...
Everett Brendan M - - 2008
BACKGROUND: Current guidelines suggest consideration of initial combination therapy for patients with stage 2 hypertension, but rates of hypertension treatment and control in clinical practice vary according to age, race, sex, and body mass index (BMI). OBJECTIVE: This was a prespecified subgroup analysis of one of the primary efficacy end ...
Forfia Paul R - - 2008
Hyponatremia is associated with decompensated heart failure and poor prognosis in patients with left ventricular systolic dysfunction. We sought to determine if hyponatremia is associated with right heart failure and worse prognosis in patients with pulmonary arterial hypertension (PAH). We prospectively followed 40 patients with PAH and examined the relationship ...
Mistry Goutam C - - 2008
The effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on ambulatory blood pressure was assessed in nondiabetic patients with mild to moderate hypertension in a randomized, double-blind, placebo-controlled, 3-period crossover study. Nineteen patients on stable treatment with antihypertensive agent(s) received sitagliptin 100 mg b.i.d., 50 mg b.i.d., or placebo for 5 ...
Elliott Paul - - 2008
Raised blood pressure is a leading cause of morbidity and mortality worldwide; improved nutritional approaches to population-wide prevention are required. Few data are available on dietary phosphorus and blood pressure and none are available on possible combined effects of phosphorus, magnesium, and calcium on blood pressure. The International Study of ...
Anderson James W - - 2008
BACKGROUND: Prior clinical trials suggest that the Transcendental Meditation technique may decrease blood pressure of normotensive and hypertensive individuals but study-quality issues have been raised. This study was designed to assess effects of Transcendental Meditation on blood pressure using objective quality assessments and meta-analyses. METHODS: PubMed and Cochrane databases through ...
Fang Jing - - 2008
BACKGROUND: Uncontrolled hypertension is a common and important risk factor for heart disease and stroke. Nevertheless, the control rate among patients taking prescribed medication and/or therapeutic lifestyle modification has remained about the same for the past several decades. METHODS: We analyzed 2003 and 2004 National Ambulatory Medical Care Survey (NAMCS) ...
Weycker Derek - - 2008
BACKGROUND: Although information concerning the attainment of goal blood pressure for patients commencing antihypertensive therapy is available from controlled trials, no studies have examined this issue in the context of typical clinical practice. OBJECTIVE: To examine attainment of blood pressure control over time in patients initiating antihypertensive therapy in clinical ...
Davenport Andrew - - 2008
BACKGROUND: Cardiovascular disease remains the most common cause of mortality in end-stage kidney failure patients with diabetes. To improve blood pressure control, and reduce cardiovascular risk, in 2002 the UK Renal Association Standards' Committee introduced pre- and post-dialysis target blood pressures of <140/90 and <130/80 mm Hg, respectively. METHODS: We ...
Guo Xinfeng - - 2008
OBJECTIVES: This study was designed to quantitatively assess the effectiveness of self-practiced qigong for treatment of essential hypertension. METHODS: Six major electronic databases were searched up to July 2006 to retrieve any potential randomized controlled trials designed to evaluate the clinical effectiveness of self-practiced qigong for essential hypertension reported in ...
Ishikawa Joji - - 2008
We evaluated whether morning minus evening systolic blood pressure (SBP) difference (MEdif) in home blood pressure measurements can be a marker for hypertensive target organ damage. The authors analyzed 611 hypertensive patients who had high morning SBP levels (>/=135 mm Hg). The patients with morning hypertension (MEdif >/=15 mm Hg, ...
Lumley Thomas - - 2008
In randomized trials of primary prevention, there has been interest in the persistence of a beneficial effect of therapy after treatment has been stopped. We investigated the impact of measurement error in the outcome on results of the trial of preventing hypertension (TROPHY), a trial of candesartan vs. placebo for ...
Tomlinson D R DR Department of Cardiac Rhythm Management, John Radcliffe Hospital, Headley Way, Headington, Oxford OX3 9DU, - - 2008
To examine the efficacy of bolus dose intravenous amiodarone for the pharmacological termination of haemodynamically-tolerated sustained monomorphic ventricular tachycardia (VT). Retrospective case series of consecutive emergency admissions with haemodynamically-tolerated sustained monomorphic VT administered bolus dose intravenous amiodarone 300 mg, according to current UK advanced life support practice guidelines. Pharmacological termination ...
Davenport A - - 2008
Cardiovascular disease remains the most common cause of mortality in patients with end-stage kidney disease treated by regular hemodialysis. To improve blood pressure control and reduce cardiovascular risk, the United Kingdom Renal Association standards committee introduced pre- and post-dialysis target blood pressures of less than 140/90 and 130/80 mm Hg, ...
Engberink Mariëlle F - - 2008
Milk-derived peptides with ACE-inhibiting properties may have antihypertensive effects in humans. We conducted a randomized double-blind placebo-controlled trial to examine the blood pressure lowering potential of 2 ACE-inhibiting lactotripeptides, ie, Isoleucine-Proline-Proline and Valine-Proline-Proline. We included 135 Dutch subjects with elevated systolic blood pressure who were otherwise healthy and who received ...
Thanakitcharu Prasert - - 2007
BACKGROUND: Anemia is common in end-stage renal disease (ESRD) patients and an important determinant for left ventricular hypertrophy (LVH) in dialysis patients. There are increasing numbers of biosimilar epoetin-alfa entering Thailand. OBJECTIVE: To conduct a prospective trial to evaluate the efficacy and safety of a biosimilar epoetin-alfa (epoetin) (Espogen) in ...
Minutolo Roberto - - 2007
BACKGROUND: Nondipping status is associated with greater cardiovascular morbidity and mortality and faster progression of chronic kidney disease (CKD). We examined whether shifting 1 antihypertensive drug from morning to evening restores the circadian rhythm of blood pressure in nondipper patients with CKD. STUDY DESIGN: 8-week clinical trial without a control ...
Edwards Randi L - - 2007
Epidemiological studies report that quercetin, an antioxidant flavonol found in apples, berries, and onions, is associated with reduced risk of coronary heart disease and stroke. Quercetin supplementation also reduces blood pressure in hypertensive rodents. The efficacy of quercetin supplementation to lower blood pressure in hypertensive humans has never been evaluated. ...
Neutel J M - - 2008
This prospective, double-blind, parallel-group study randomized patients with moderate hypertension (seated systolic blood pressure (SeSBP) 160-179 mm Hg when seated diastolic blood pressure (SeDBP) <110 mm Hg; or SeDBP 100-109 mm Hg when SeSBP <180 mm Hg) 3:1:1 to treatment with irbesartan 300 mg/hydrochlorothiazide (HCTZ) 25 mg combination therapy (n=328), ...
Ahimastos Anna A AA Alfred and Baker Medical Unit, Baker Heart Research Institute, Central Melbourne, Victoria, - - 2007
Aortic stiffness is increased in Marfan syndrome contributing to aortic dilatation and rupture, the major cause of premature death in this population. Angiotensin-converting enzyme inhibitors have been shown to reduce arterial stiffness. To determine whether perindopril therapy reduces aortic stiffness and attenuates aortic dilatation in patients with Marfan syndrome. A ...
Millar Philip J - - 2007
OBJECTIVE: To examine the longitudinal effects of isometric handgrip (IHG) exercise training on blood pressure using hierarchical linear modeling. METHODS: Data from 43 participants who were medicated for hypertension at the time of training were amalgamated from three previous investigations. In each study, IHG training was completed 3 days/week for ...
Lehrmann Jill F - - 2007
OBJECTIVES: To determine if dissemination of the American College of Emergency Physicians clinical policy on hypertension to emergency physicians would lead to improvements in blood pressure reassessment and referral of emergency department (ED) patients with elevated blood pressure. METHODS: Two academic centers implemented a pre-post intervention design, with independent samples ...
Marshall T - - 2008
This paper aims to identify how many young adults on antihypertensive treatment have been misclassified as hypertensive. We identified subjects aged under 35 on antihypertensive treatment, from the Health Surveys for England, 1998-2004. Pretreatment systolic and diastolic blood pressures were calculated by adjusting on-treatment blood pressures for the effects of ...
Ranjbar Fatemeh - - 2007
OBJECTIVE: To evaluate the efficacy of relaxation technique as an adjunctive therapy for control of hypertension. METHODS: From April 2004 to January 2005, with a single blinded randomized controlled design, 220 patients with newly diagnosed essential moderate to severe hypertension who needed drug therapy were included in the study. The ...
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