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Scarparo Henrique Clasen - - 2013
Cardiovascular effects of epinephrine, especially on blood pressure (BP) and heart rate (HR), have been well documented. When present in dental local anesthetic solutions, epinephrine concentration ranges from 5 to 20 µg/mL. Doses less than 200 µg are recommended to be clinically safe. This study investigated the effects of the ...
Gianesello Lara - - 2013
A hemodynamic event such as hypertension after interscalene block (ISB) is a complication that is often overlooked. The irregular spread of local anesthetic would cause a blockade of carotid sinus baroreceptors leading to the adverse event. The purpose of the present study is to compare ultrasound and neurostimulation technique in ...
Nair Bala G - - 2013
Intraoperative hypotension and hypertension are associated with adverse clinical outcomes and morbidity. Clinical decision support mediated through an anesthesia information management system (AIMS) has been shown to improve quality of care. We hypothesized that an AIMS-based clinical decision support system could be used to improve management of intraoperative hypotension and ...
Aarnes Turi K - - 2013
To determine the level of agreement between an oscillometric (O-NIBP) and an invasive method (IBP) of monitoring arterial blood pressure (ABP) in anesthetized sheep, goats, and cattle. Prospective clinical study. Twenty sheep and goats, 20 cattle weighing <150 kg body weight, and 20 cattle weighing >150 kg body weight. Animals were anesthetized ...
Wolf Andrew R AR Department of Paediatric Intensive Care, Bristol Royal Children's Hospital, Bristol, UK; Department of Paediatric Anaesthesia, Bristol Royal Children's Hospital, Bristol, - - 2014
Development of the cardiovascular system through the last trimester of pregnancy and the subsequent neonatal period is profound. Morphological changes within the myocardium make the heart vulnerable to challenges such as fluid shifts and anesthetic drugs. The sensitivity of the myocardium to metabolic challenges and potential harm of drugs needed ...
Kijtawornrat Anusak - - 2013
The evaluation of proarrhythmic and hemodynamic liabilities for new compounds remains a major concern of preclinical safety assessment paradigms. Contrastingly, albeit functional liabilities can also translate to clinical morbidity and mortality, lesser preclinical efforts are focused on the evaluation of drug-induced changes in inotrope and lusitrope, particularly in the setting ...
Degerli Semih - - 2013
The effects of different body positions on the middle ear were reported in several studies, but there are no data about the effects on patients under general anesthesia. The aim of this study is to determine the effect of prone position on middle ear pressure (MEP) during general anesthesia without ...
Grap Mary Jo - - 2013
To determine the effect of sedation on physiologic responses and comfort before, during and after a noxious stimulus (endotracheal tube suctioning). The sample was a subset of a larger, longitudinal descriptive study, blood for endorphins and saliva for alpha-amylase were obtained before and after suctioning. Heart rate (HR), respiration rate ...
Tran Khoa - - 2013
We evaluated the effect of propofol on resting anal sphincter pressure (RP) during anorectal manometry (ARM) performed under general anesthesia in 20 children with chronic constipation. After propofol bolus administration, there was a significant decrease in the RP in 95% of subjects from a mean of 51.5 ± 15.3 mmHg to a ...
Kweon Tae Dong - - 2013
Hypotension is a common phenomenon after spinal anesthesia in hypertensive patients. We investigated whether heart rate variability could predict the occurrence of hypotension after spinal anesthesia in hypertensive patients. Forty-one patients undergoing spinal anesthesia were included. Heart rate variability was measured at five different time points such as before fluid ...
Masoudifar Mehrdad M Department of Anesthesiology, Kashani Hospital, Isfahan, - - 2013
Most neurosurgeons and anesthesiologists prefer the less invasive intervention for most surgeries; recently, the lumbar anesthesia is more popular method. In this study we have tried to distract the attention of the patients to their favorite video-clip instead of their surrounding operating room background to evaluate the hemodynamic as well ...
Masoudifar Mehrdad M Department of Anesthesiology, Ayatolah Kashani Hospital, Isfahan University of Medical Sciences, Isfahan, - - 2013
Etomidate and Propofol are common anesthetic agents. Previous studies say that Etomidate can be used in patients with limited hemodynamic reserve and Propofol can lead to more hemodynamic instabilities. This study was performed to explore the cardiovascular response during the induction of anesthesia with Etomidate or for comparison, Propofol in ...
Chan Wei-Hung - - 2013
To investigate whether a target-controlled infusion (TCI) with propofol, a method having theoretically better control of drug concentration, would produce less cardiovascular and respiratory suppression than intermittent bolus of a sedative-analgesic cocktail regimen in deep sedation for gastrointestinal endoscopy. One hundred participants underwent esophagoduodenoscopy (EGD) and 120 underwent colonoscopy were ...
Ioannou Christos V - - 2013
To investigate the effect of general anesthesia on aortic compliance and other cardiovascular hemodynamics in chronically instrumented pigs with compliant and noncompliant (stiff) aortas. Experimental study. University animal laboratory. Twelve adult Yucatan miniature pigs. Chronic instrumentation of a compliant (control; n = 7) and noncompliant (n = 5) group to ...
Bencze M - - 2013
Most anesthetics induce characteristic hemodynamic changes leading to blood pressure (BP) reduction but the role of renin-angiotensin system (RAS), sympathetic nervous system (SNS) and nitric oxide (NO) synthesis in this BP reduction is unknown. We therefore studied the influence of four widely used anesthetics - pentobarbital (P), isoflurane (ISO), ketamine-xylazine ...
Riphaus A - - 2013
Background and study aims: The use of sedation (e. g., of short-acting propofol) for gastrointestinal endoscopy has shown an upward trend in the USA and Europe over the last decade. To improve patient's safety different nationwide guidelines have been developed. This survey aimed at providing nationwide re-evaluated data 3 years ...
Kinney Matthew E - - 2013
Dexmedetomidine, a highly selective alpha-2 adrenergic agonist and dextrorotary enantiomer of medetomidine, was combined with ketamine and used to immobilize 14 free-ranging Choloepus hoffmanni (Hoffmann's two-toed sloths) and 11 Bradypus variegatus (brown-throated three-toed sloths) in Upala, Costa Rica. Following intramuscular injection of ketamine (2.1 mg/kg) and dexmedetomidine (11 microg/kg), heart ...
Vaschetto Rosanna - - 2013
Evaluating the physiologic effects of varying depths of propofol sedation on patient-ventilator interaction and synchrony during pressure support ventilation and neurally adjusted ventilatory assist. Prospective crossover randomized controlled trial. University hospital ICU. Fourteen intubated patients mechanically ventilated for acute respiratory failure. Six 25-minute trials randomly performed applying both pressure support ...
Chiarandini Paolo - - 2013
The aim of this study was to investigate the effects of clinical dosages of norepinephrine and dobutamine on sublingual microcirculation during general anesthesia with sevoflurane in minor surgical procedures. This prospective study was performed on patients scheduled for breast cancer surgery. Tertiary care university hospital. Twenty patients undergoing elective surgery. ...
Abutarboush Rania - - 2013
Hemoglobin-based oxygen carrier-201 (HBOC) was developed as a resuscitative fluid but concerns exist over potentially adverse vasoconstriction. This study evaluated whether concurrent IV N-acetyl-L-cysteine (NAC) or hyaluronic acid (HA) would attenuate HBOC-associated vasoconstriction, assessed by systemic blood pressures and cerebral pial microvasculature, when administered to healthy, anesthetized rats. Rats (8-9/group) ...
Wu Jing - - 2013
Epinephrine was recently shown to induce a hypotension episode. Activation of β2-adrenoceptors with smooth muscle relaxation may be the underlying mechanism. This study investigated the effects of ICI 118551, a β2-adrenoceptors antagonist, on epinephrine-induced blood pressure reduction via different administration routes in rats. A total of 144 Sprague-Dawley rats were ...
Park Sang-Jin - - 2013
Jaw-thrust is a noxious stimulus that might induce sympathetic responses. The purpose of this study, was to evaluate the effects of jaw-thrust on sympathetic responses. We investigated seventy three patients. Patients who received general anesthesia were randomly divided into a control group (maintenance of combined airway maneuver with head tilt, ...
Moorer Jeremiah D - - 2013
A blinded, prospective, randomized crossover study was performed to determine the effects of ampicillin Na/sulbactam Na and enrofloxacin on the blood pressure (BP) of healthy anesthetized dogs. Eight dogs were anesthetized three different times. They randomly received enrofloxacin, ampicillin Na/sulbactam Na, and saline. Systolic, diastolic, and mean arterial BPs (SAP, ...
Ambrósio Aline M - - 2013
To assess if positive end-expiratory pressure (PEEP) titration improves gas exchange and respiratory mechanics, without hemodynamic impairment in horses during anesthesia. Prospective, randomized study. Thirteen isoflurane-anesthetized healthy horses. After 60 minutes of anesthesia with spontaneous breathing, mechanical ventilation was initiated with an inspiratory-expiratory ratio of 1:2, PEEP of 5 cmH2 O, ...
Iwayama Sachiko - - 2013
Despite the implementation of liberal preoperative fasting routines, it is unclear whether preoperative oral rehydration solution intake volume affects blood pressure during general anesthesia. We enrolled 60 patients (American Society of Anesthesiologists status I/II) undergoing tympanoplasty. Patients drank 200-1,000 ml oral rehydration solution until 2-3 h before anesthesia induction. Anesthesia was induced ...
Yu Tao - - 2013
Hypotension due to the induction of sedation with dexmedetomidine infusion may be harmful in critically ill patients. Changes in pulse pressure induced by the passive leg raising test (PLR-ΔPP) as marker of fluid responsiveness, assessed prior to sedation, may predict hemodynamic changes. The present study was to investigate the power ...
Diniz Miriely Steim - - 2013
To compare the cardiopulmonary effects and the quality of anesthesia of the extradural lidocaine in combination with fentanyl or morphine in bitches undergoing ovariohysterectomy. Sixteen female dogs, were sedated with intramuscular acepromazine (0.05mg kg-1), followed by anesthetic induction with intravenous propofol (4mg kg-1), to perform the lumbosacral puncture. The animals ...
Meng Xianghu - - 2013
The Philips Intellivue MP50 monitor provides a method for non-invasive, near-continuous blood pressure (BP) monitoring and is designed to be an alternative to direct intra-arterial BP (IABP) measurement. However, no studies have specifically compared non-invasive and invasive BP measurements using the monitor. The present retrospective study observed 515 patients undergoing ...
Tabari Masoomeh M Department of Anesthesiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR - - 2013
Direct laryngoscopy and tracheal intubation can result in blood pressure and heart rate increase which in turn may lead to myocardial ischemia, cerebral hemorrhage, and even death in susceptible patients. Tizanidine is α2-receptor agonists that suppresses central sympathetic system. This study evaluates the effects of oral Tizanidine on hemodynamic responses ...
Oel Carolin - - 2013
OBJECTIVE: Analysis of any effect of retrobulbar block during ocular surgery on heart rate variability and oculocardiac reflex. STUDY DESIGN: Prospective study. ANIMAL STUDIED: Horses (n = 16) undergoing eye enucleation due to chronic ophthalmologic diseases. PROCEDURE: Eye enucleation was performed under general anesthesia. The horses were randomly assigned to the first ...
Yokoe Chizuko - - 2013
OBJECTIVE: Decrease in arterial blood pressure is a prominent adverse reaction during propofol (Disoprivan; AstraZeneca K.K., Osaka, Japan) sedation. The purpose of this prospective randomized study was to explore the effects of nitrous oxide (N2O) on the hypotensive response during propofol sedation. STUDY DESIGN: Twenty-six healthy volunteers received intravenous sedation ...
Brekke Hege Kristin - - 2013
BACKGROUND:: A highly positive intraoperative fluid balance should be prevented as it negatively impacts patient outcome. Analysis of volume-kinetics has identified an increase in interstitial fluid volume after crystalloid fluid loading during isoflurane anesthesia. Isoflurane has also been associated with postoperative hypoxemia and may be associated with an increase in ...
Dewhirst Elisabeth - - 2013
STUDY OBJECTIVE: To assess the accuracy of a noninvasive continuous blood pressure (BP) monitor in patients who are positioned prone in the operating room. DESIGN: Prospective study. SETTING: Operating room at a children's hospital. PATIENTS: 20 pediatric patients, aged 13.8 ± 2 years, and 63.7 ± 18.8 kg, scheduled for ...
Adlesic Edward C - - 2013
Perioperative hypertension is a common problem. If hypertension is left untreated in patients at risk, infarctions and stroke are possible. There are limited choices of antihypertensive agents for the office. Aggressive antihypertensive therapy is not indicated because most of the episodes seen in the office are hypertensive urgencies and not ...
Keating Stephanie C J - - 2013
Objective-To evaluate the cardiopulmonary effects of IV fentanyl administration in dogs during isoflurane anesthesia and during anesthetic recovery with or without dexmedetomidine or acepromazine. Animals-7 sexually intact male purpose-bred hound-type dogs aged 11 to 12 months. Procedures-Dogs received a loading dose of fentanyl (5 μg/kg, IV) followed by an IV ...
Jeong Hee Jin - - 2013
Purpose: This study aims to investigate the most appropriate effect-site concentration of remifentanil to minimize cardiovascular changes during inhalation of high concentration desflurane. Materials and Methods: Sixty-nine American Society of Anesthesiologists physical status class I patients aged 20-65 years were randomly allocated into one of three groups. Anesthesia was induced ...
Rabadi Daher - - 2013
To compare the effect of prophylactic administration of normal saline against the hypotensive effect of propofol in female patients booked for gynecological procedures. Sixty nine ASA (I, II) patients were randomly allocated into two groups, group 1 received 5mL.kg(-1) of 0.9% normal saline 10 minutes before induction, whereas group 2 ...
Lee Hae Jin - - 2013
We present successful epidural anesthesia and assisted mechanical ventilation in a parturient woman with respiratory failure. A 41-year-old woman at 35 weeks' of gestation was entering labor. She was pneumonectomized on the left, had bronchiectasis on the remnant lung, and was under assisted mechanical ventilation by continuous positive airway pressure ...
Rabadi Daher D Department of Anesthesiology, Jordan University of Science & Technology, Irbid, Jordan. Electronic address: - - 2013
To compare the effect of prophylactic administration of normal saline against the hypotensive effect of propofol in female patients booked for gynecological procedures. Sixty nine ASA (I, II) patients were randomly allocated into two groups, group 1 received 5mL.kg(-1) of 0.9% normal saline 10minutes before induction, whereas group 2 received ...
Ida Keila K - - 2013
OBJECTIVE: To determine if pressure support ventilation (PSV) weaning from general anesthesia affects ventilation or oxygenation in horses. STUDY DESIGN: Prospective randomized clinical study. ANIMALS: Twenty client-owned healthy horses aged 5 ± 2 years, weighing 456 ± 90 kg. METHODS: In the control group (CG; n = 10) weaning was performed by a gradual decrease in respiratory rate ...
Bassani Tito - - 2013
During general anesthesia positive pressure mechanical ventilation (MV) profoundly affects intrathoracic pressure and venous return, thus soliciting cardiopulmonary reflexes and modifying stroke volume. As a consequence heart period, approximated as the temporal distance between two consecutive R peaks on the ECG (RR), and systolic arterial pressure (SAP) variability series are ...
Gunderson Erin G - - 2013
Objective-To compare effects of anesthetic induction with midazolam-propofol or midazolam-etomidate on intraocular pressure (IOP), pupillary diameter (PD), pulse rate, blood pressure, and respiratory rate in clinically normal dogs. Animals-18 dogs. Procedures-Dogs undergoing ophthalmic surgery received midazolam (0.2 mg/kg, IV) and either propofol or etomidate (IV) until intubatable. For all dogs, ...
Hwang Jung-Won - - 2013
: Pneumoperitoneum in the pelvic laparoscopic surgery induces a rise in the intraocular pressure (IOP). This study investigated whether IOP changes were different depending on the surgical position (Trendelenburg vs. reverse Trendelenburg) and the anesthetic drugs (propofol vs. desflurane). : A total of 100 patients scheduled for pelvic laparoscopy or ...
Ramoo S - - 2013
To evaluate the sedative, respiratory and cardiovascular effects of subcutaneously administered alfaxalone and butorphanol in a group of hyperthyroid cats. A prospective, single-centre observational study. Client-owned hyperthyroid cats (n=20) were examined and sedated with alfaxalone (3 mg/kg) and butorphanol (0.2 mg/kg) administered subcutaneously. Sedation scores, heart rate, respiratory rate and blood pressure ...
Peirovifar Ali A Ali Peirovifar, Associate Professor of Anesthesiology, Fellowship of Critical Care Medicine, Faculty of Medicine, Anesthesiology Research Team, Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, - - 2013
To compare the postoperative complications between Laryngeal Mask Airway (LMA) and endotracheal tube (ETT) during low-flow anesthesia with controlled ventilation. Eighty adult Patients with ASA class I or II were randomly allocated into two forty-patient groups (ETT or LMA). Cuff pressure was monitored during anesthesia. After high uptake period, fresh ...
Bai Renren - - 2013
A series of novel hybrids of natural isochroman-4-one bearing isopropanolamine moiety were designed, synthesized and evaluated for their antihypertensive activity. It was found that compound IIId, prepared by hybridizing N-isopropyl substituted isopropanolamine functionality to a phenolic oxygen of isochroman-4-one, exhibited potent β1-adrenoceptor blocking effect comparable to the well-known antihypertensive drug ...
Bruins Benjamin B Department of Pediatrics, Washington University in St. Louis School of Medicine, Campus Box 8028, 5th Floor MPRB, 660 S. Euclid Ave., St. Louis, MO 63110. - - 2013
The effect of various sedatives and anesthetics on vasopressor modulation of cerebral blood flow (CBF) in children is unclear. In adults, isoflurane has been described to decrease CBF to a lesser extent than fentanyl and midazolam. Most large-animal models of neurocritical care use inhaled anesthetics for anesthesia. Investigations involving modulations ...
Wajima Zen'ichiro - - 2013
PURPOSE: A decrease in blood pressure is sometimes observed when a postsurgical patient is transferred to another bed after recovering from anesthesia. However, the mechanism behind this hypotension has not been completely elucidated. The purpose of this study was to investigate and compare changes in hemodynamic properties for possible causes ...
Miller Michele - - 2013
Forty free-ranging white rhinoceros (Ceratotherium simum) were anesthetized with etorphine, azaperone, and hyaluronidase in Kruger National Park, South Africa, between February and August 2009. Eighteen rhinoceros received butorphanol in the dart combination, and 22 rhinoceros had butorphanol administered intravenously within 15 min of darting. Body position, blood gas values, heart ...
Chohan Amandeep S - - 2013
Objective-To compare effects of isoflurane and sevoflurane on intracranial pressure and cardiovascular variables at 1.0, 1.5, and 2.0 times the minimum alveolar concentration (MAC) in mechanically ventilated normocapnic dogs. Animals-6 healthy male Beagles. Procedures-The individual MAC was determined for each agent with an electrical stimulus. After a minimum of 1 ...
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